Page last updated: 2024-09-04

naproxen and estrone

naproxen has been researched along with estrone in 13 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(estrone)
Trials
(estrone)
Recent Studies (post-2010) (estrone)
4,5511,0571,42910,2664321,372

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)estrone (IC50)
Estrogen receptorHomo sapiens (human)0.1261
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.589
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.4134
Sodium-dependent serotonin transporterHomo sapiens (human)5.301
Estrogen receptor betaHomo sapiens (human)0.3743
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's7 (53.85)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bidault, R; Haumont, M; Herber, R; Magdalou, J; Siest, G; van Es, H1
Boyd, GR; Grimm, DA1
Ademollo, N; Capri, S; Patrolecco, L1
Kirchler, CG; Meischl, F; Rainer, M; Stuppner, SE1
Bila, DM; da Fonseca, EM; da Silva de Freitas, A; de Oliveira Santos, AD; do Nascimento, MTL; Dos Santos, RF; Felix, LC; Hauser-Davis, RA; Neto, JAB; Sanson, AL1

Reviews

2 review(s) available for naproxen and estrone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for naproxen and estrone

ArticleYear
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Glucuronidation of 3'-azido-3'-deoxythymidine in human liver microsomes: enzyme inhibition by drugs and steroid hormones.
    Biochimica et biophysica acta, 1992, Jun-09, Volume: 1139, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Estrone; Ethinyl Estradiol; Flurbiprofen; Glucuronosyltransferase; Humans; Microsomes, Liver; Naproxen; Phenylpropionates; Probenecid; Testosterone; Zidovudine

1992
Occurrence of pharmaceutical contaminants and screening of treatment alternatives for southeastern Louisiana.
    Annals of the New York Academy of Sciences, 2001, Volume: 948

    Topics: Animals; Carbon; Clofibric Acid; Drug-Related Side Effects and Adverse Reactions; Environmental Monitoring; Estrone; Gas Chromatography-Mass Spectrometry; Louisiana; Naproxen; Thermodynamics; Water Pollutants, Chemical

2001
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:8

    Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical

2015
Comparative study of substituted poly(4-vinylbenzyl chloride/ethylene glycol dimethacrylate) sorbents for enrichment of selected pharmaceuticals and estrogens from aqueous samples.
    Journal of hazardous materials, 2018, 08-05, Volume: 355

    Topics: Adsorption; Antipyrine; Carbamazepine; Estradiol; Estriol; Estrogens; Estrone; Ibuprofen; Methacrylates; Naproxen; Polyethylene Glycols; Polymerization; Polyvinyls; Water Pollutants, Chemical; Water Purification

2018
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
    Marine pollution bulletin, 2022, Volume: 184

    Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical

2022