Page last updated: 2024-09-04

naproxen and dinoprost

naproxen has been researched along with dinoprost in 21 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(dinoprost)
Trials
(dinoprost)
Recent Studies (post-2010) (dinoprost)
4,5511,0571,42911,5549401,936

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)dinoprost (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.0025
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.0713
Prostaglandin G/H synthase 1Homo sapiens (human)0.14
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.3
Prostaglandin G/H synthase 2Homo sapiens (human)0.14
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)4.2
Prostaglandin F2-alpha receptorBos taurus (cattle)0.14
Prostaglandin F2-alpha receptorHomo sapiens (human)0.0139
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.216
Prostaglandin D2 receptorHomo sapiens (human)4.5
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.287

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199013 (61.90)18.7374
1990's3 (14.29)18.2507
2000's3 (14.29)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Paulsrud, JR; Tobias, LD; Vane, FM1
Bremme, K; Bygdeman, M; Eneroth, P; Gottlieb, C; Kindahl, H; Nilsson, B; Olsson, M; Svanborg, K1
Li, Y; Liu, YQ; Tang, DC; Wu, XR; Zhao, BR1
Chan, WY2
Christensen, P; Kamper, AL; Strandgaard, S; Svendsen, UG1
Bendvold, E; Bygdeman, M; Cai, QH; Eneroth, P; Gottlieb, C; Svanborg, K1
Chan, WY; Fuchs, F; Powell, AM1
Akerlund, M; Forsling, ML; Kindahl, H; Strömberg, P1
Akerlund, M; Kostrzewska, A; Laudański, T1
Kaihola, HL; Kangas, L; Nieminen, L; Pulkkinen, M; Túri, S1
Dubin, NH; Ghodgaonkar, RB; Henzl, MR; Hoffman, S; Jones, GS; Rosenwaks, Z1
Gemzell-Danielsson, K; Hamberg, M1
Bennegård-Edén, B; Hahlin, M; Kindahl, H1
Dharmarajan, AM; Endo, K; Wallach, EE; Zanagnolo, V1
Jurenka, RA; Stanley, DW; Tunaz, H1
Büyükgüzel, K; Putnam, SM; Stanley, D; Tunaz, H1
Baylas, H; Huseyinov, A; Vardar, S1
Bentley, JP; Brewer, CB; Day, LB; Waddell, DE1

Trials

4 trial(s) available for naproxen and dinoprost

ArticleYear
Effects of sulindac and naproxen in patients with chronic glomerular disease.
    Scandinavian journal of rheumatology. Supplement, 1986, Volume: 62

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Creatinine; Dinoprost; Dinoprostone; Female; Glomerulonephritis; Humans; Indenes; Kidney; Male; Middle Aged; Naproxen; Prostaglandins E; Prostaglandins F; Random Allocation; Sulindac

1986
Effects of naproxen sodium on menstrual prostaglandins and primary dysmenorrhea.
    Obstetrics and gynecology, 1983, Volume: 61, Issue:3

    Topics: Adult; Dinoprost; Dinoprostone; Dysmenorrhea; Female; Humans; Menstruation; Naproxen; Prostaglandins E; Prostaglandins F

1983
The effect of antiprogestin (RU 486) and prostaglandin biosynthesis inhibitor (naproxen) on uterine fluid prostaglandin F2 alpha concentrations.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:9

    Topics: Body Fluids; Dinoprost; Embryo Implantation; Female; Humans; Luteal Phase; Mifepristone; Naproxen; Time Factors; Uterus

1994
Effects of selective cyclooxygenase-2 inhibition on gingival tissue levels of prostaglandin E2 and prostaglandin F2alpha and clinical parameters of chronic periodontitis.
    Journal of periodontology, 2003, Volume: 74, Issue:1

    Topics: Adult; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dental Plaque Index; Dental Scaling; Dinoprost; Dinoprostone; Double-Blind Method; Female; Follow-Up Studies; Gingiva; Humans; Isoenzymes; Male; Matched-Pair Analysis; Membrane Proteins; Middle Aged; Naproxen; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Placebos; Prostaglandin-Endoperoxide Synthases; Root Planing; Statistics as Topic; Statistics, Nonparametric; Sulfonamides

2003

Other Studies

17 other study(ies) available for naproxen and dinoprost

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The biosynthesis of 1a, 1b-dihomo-PGF2 and 1a,1b-dihomo-PGF2 alpha from 7, 10, 13, 16-docosatetraenoic acid by an acetone-pentane powder of sheep vesicular gland microsomes.
    Prostaglandins, 1975, Volume: 10, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetone; Alkanes; Animals; Borohydrides; Chromatography, Gas; Chromatography, Thin Layer; Depression, Chemical; Dinoprost; Erucic Acids; Fatty Acids, Unsaturated; Male; Mass Spectrometry; Microsomes; Naproxen; Oxygen Consumption; Prostaglandins E; Prostaglandins F; Seminal Vesicles; Sheep

1975
15-Keto-13,14-dihydroprostaglandin E2- and F2 alpha-metabolite levels in blood from men and women given prostaglandin E2 orally.
    Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 37, Issue:3

    Topics: Administration, Oral; Adult; Dinoprost; Dinoprostone; Female; Humans; Male; Menstrual Cycle; Naproxen; Prostaglandins

1989
Influence of naproxen on uterine PGF2 alpha and the antifertility effect of IUDs in rats.
    Eicosanoids, 1989, Volume: 2, Issue:1

    Topics: Animals; Dinoprost; Embryo Implantation; Female; Fertility; Intrauterine Devices; Naproxen; Rats; Rats, Inbred Strains; Uterus

1989
Enhanced prostaglandin synthesis in the parturient rat uterus and its effects on myometrial oxytocin receptor concentrations.
    Prostaglandins, 1987, Volume: 34, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Dinoprostone; Female; Labor, Obstetric; Microsomes; Myometrium; Naproxen; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Oxytocin; Thromboxane B2; Uterine Contraction; Uterus

1987
Renal prostaglandins and natriuretic action of oxytocin and vasopressin in rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:2

    Topics: Animals; Dinoprost; Dinoprostone; Electrolytes; Kidney; Male; Naproxen; Natriuresis; Oxytocin; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred Strains; Vasopressins

1988
The effect of naproxen on the concentration of prostaglandins in human seminal fluid.
    Fertility and sterility, 1985, Volume: 43, Issue:6

    Topics: Alprostadil; Dinoprost; Humans; Male; Naproxen; Prostaglandins; Prostaglandins E; Prostaglandins F; Semen; Sperm Count; Sperm Motility

1985
Involvement of prostaglandins in vasopressin stimulation of the human uterus.
    British journal of obstetrics and gynaecology, 1983, Volume: 90, Issue:4

    Topics: Adult; Arginine Vasopressin; Dinoprost; Female; Humans; Lypressin; Menstruation; Naproxen; Pressure; Prostaglandins; Prostaglandins F; Uterus; Vasopressins

1983
Interaction of vasopressin and prostaglandins in the nonpregnant human uterus.
    Prostaglandins, 1984, Volume: 27, Issue:3

    Topics: Arginine Vasopressin; Arteries; Dinoprost; Dinoprostone; Female; Humans; In Vitro Techniques; Indomethacin; Lypressin; Myometrium; Naproxen; Prostaglandins E; Prostaglandins F; Regional Blood Flow; Uterus

1984
The effect of antidiuretic hormone, indomethacin and naproxen on prostaglandin synthesis of experimentally infected and healthy kidneys.
    International urology and nephrology, 1982, Volume: 14, Issue:3

    Topics: Animals; Arginine Vasopressin; Deamino Arginine Vasopressin; Dinoprost; Escherichia coli Infections; Female; Indomethacin; Kidney; Naproxen; Nephritis; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains

1982
Naproxen sodium, aspirin, and placebo in primary dysmenorrhea. Reduction of pain and blood levels of prostaglandin F2-alpha metabolite.
    American journal of obstetrics and gynecology, 1981, Jul-01, Volume: 140, Issue:5

    Topics: Activities of Daily Living; Adolescent; Adult; Aspirin; Dinoprost; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Humans; Naproxen; Placebos; Prostaglandins F

1981
Interaction between oxytocin and prostaglandin F2 alpha in human corpus luteum?
    Human reproduction (Oxford, England), 1995, Volume: 10, Issue:9

    Topics: Adult; Corpus Luteum; Cyclooxygenase Inhibitors; Dinoprost; Drug Interactions; Female; Humans; Kinetics; Luteal Phase; Naproxen; Ovary; Oxytocin; Progesterone

1995
Effects of acetylsalicylic acid (aspirin) and naproxen sodium (naproxen) on ovulation, prostaglandin, and progesterone production in the rabbit.
    Fertility and sterility, 1996, Volume: 65, Issue:5

    Topics: Animals; Aspirin; Chorionic Gonadotropin; Dinoprost; Female; Naproxen; Ovarian Follicle; Ovary; Ovulation; Progesterone; Prostaglandins; Rabbits

1996
Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta.
    Insect biochemistry and molecular biology, 2001, Mar-15, Volume: 31, Issue:4-5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Fat Body; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Indomethacin; Microsomes; Moths; Naproxen; Prostaglandin D2; Prostaglandins; Prostaglandins A; Temperature

2001
Prostaglandin biosynthesis by midgut tissue isolated from the tobacco hornworm, Manduca sexta.
    Insect biochemistry and molecular biology, 2002, Volume: 32, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Culture Techniques; Cyclooxygenase Inhibitors; Digestive System; Dinoprost; Dinoprostone; Hydrogen-Ion Concentration; Indomethacin; Insect Proteins; Manduca; Molecular Structure; Moths; Naproxen; Prostaglandin D2; Prostaglandins; Prostaglandins A; Prostaglandins B; Subcellular Fractions; Temperature; Time Factors

2002
Resistance exercise and naproxen sodium: effects on a stable PGF2α metabolite and morphological adaptations of the upper body appendicular skeleton.
    Inflammopharmacology, 2015, Volume: 23, Issue:6

    Topics: Adaptation, Physiological; Adult; Bones of Upper Extremity; Cyclooxygenase Inhibitors; Dinoprost; Double-Blind Method; Exercise; Humans; Inflammation; Male; Naproxen; Prostaglandin-Endoperoxide Synthases; Resistance Training; Young Adult

2015