naproxen has been researched along with danazol in 17 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (danazol) | Trials (danazol) | Recent Studies (post-2010) (danazol) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 2,402 | 288 | 279 |
| Protein | Taxonomy | naproxen (IC50) | danazol (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Glucocorticoid receptor | Homo sapiens (human) | 4.314 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.019 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 4.314 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 5.698 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 0.3 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.012 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 4.314 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 4.314 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 5.698 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 4.314 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 8.85 | |
| Cytochrome P450 2J2 | Homo sapiens (human) | 0.0317 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 6.842 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 11 (64.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Fraser, IS; McCarron, G | 1 |
| Duncan, KM; Hart, LL | 1 |
| Becker, JN; Broomall, CF; Crowl, CA; Elder, EJ; Evans, JC; Fransen, KL; Gillespie, IB; Hitt, JE; Kupperblatt, GB; Rogers, TL; Todd, C; Tucker, CJ; Wilson, DL | 1 |
| Brown, J; Farquhar, C | 1 |
| Bofill Rodriguez, M; Brown, J; Lethaby, A; Weterings, MA; Wise, MR | 1 |
4 review(s) available for naproxen and danazol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Nonsteroidal antiinflammatory drugs in menorrhagia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Danazol; Female; Humans; Ibuprofen; Mefenamic Acid; Menorrhagia; Naproxen | 1993 |
Oral contraceptive pill for heavy menstrual bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral; Danazol; Drug Therapy, Combination; Female; Humans; Mefenamic Acid; Menorrhagia; Naproxen | 2009 |
Combined hormonal contraceptives for heavy menstrual bleeding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Danazol; Drug Therapy, Combination; Female; Humans; Intrauterine Devices, Medicated; Levonorgestrel; Mefenamic Acid; Menorrhagia; Naproxen; Nausea; Placebos; Progestins; Randomized Controlled Trials as Topic | 2019 |
1 trial(s) available for naproxen and danazol
| Article | Year |
|---|---|
Randomized trial of 2 hormonal and 2 prostaglandin-inhibiting agents in women with a complaint of menorrhagia.
Topics: Contraceptives, Oral, Combined; Danazol; Drug Therapy, Combination; Female; Humans; Mefenamic Acid; Menorrhagia; Naproxen | 1991 |
12 other study(ies) available for naproxen and danazol
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development and characterization of a scalable controlled precipitation process to enhance the dissolution of poorly water-soluble drugs.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Danazol; Drug Compounding; Microscopy, Electron, Scanning; Microspheres; Naproxen; Particle Size; Pharmaceutical Preparations; Solubility; Solvents; X-Ray Diffraction | 2004 |