Page last updated: 2024-09-04

naproxen and cyclobenzaprine

naproxen has been researched along with cyclobenzaprine in 9 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(cyclobenzaprine)
Trials
(cyclobenzaprine)
Recent Studies (post-2010) (cyclobenzaprine)
4,5511,0571,4292314694

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)cyclobenzaprine (IC50)
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)10

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Felson, DT; Goldenberg, DL; Simms, RW1
Bijur, PE; Davitt, M; Dym, AA; Esses, D; Friedman, BW; Gallagher, EJ; Holden, L; Solorzano, C1
Frazer, K; Stevermer, JJ1
Kennedy, DJ; Kumbhare, D; Schneider, BJ1
Gottlieb, M; Njie, A1

Reviews

1 review(s) available for naproxen and cyclobenzaprine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for naproxen and cyclobenzaprine

ArticleYear
Development of preliminary criteria for response to treatment in fibromyalgia syndrome.
    The Journal of rheumatology, 1991, Volume: 18, Issue:10

    Topics: Amitriptyline; Double-Blind Method; Fibromyalgia; Humans; Naproxen; Regression Analysis

1991
Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial.
    JAMA, 2015, Oct-20, Volume: 314, Issue:15

    Topics: Acetaminophen; Acute Disease; Adult; Aged; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Low Back Pain; Male; Middle Aged; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Treatment Outcome

2015
Comparison of naproxen with cyclobenzaprine, oxycodone-acetaminophen, and placebo for the treatment of acute low back pain.
    CJEM, 2016, Volume: 18, Issue:6

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adult; Amitriptyline; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Emergency Service, Hospital; Female; Follow-Up Studies; Hospitals, Teaching; Humans; Low Back Pain; Male; Middle Aged; Naproxen; Oxycodone; Pain Measurement; Patient Satisfaction; Severity of Illness Index; Treatment Outcome; Young Adult

2016

Other Studies

5 other study(ies) available for naproxen and cyclobenzaprine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
PURLs: More isn't better with acute low back pain treatment.
    The Journal of family practice, 2016, Volume: 65, Issue:6

    Topics: Acetaminophen; Amitriptyline; Drug Combinations; Female; Humans; Low Back Pain; Male; Muscle Relaxants, Central; Naproxen; Oxycodone; Pain Measurement; Randomized Controlled Trials as Topic; Treatment Outcome

2016
Second-Order Peer Reviews of Clinically Relevant Articles for the Physiatrist: Naproxen with Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo to Treating Acute Low Back Pain: A Randomized Clinical Trial.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:6

    Topics: Acetaminophen; Amitriptyline; Humans; Low Back Pain; Naproxen; Oxycodone; Peer Review; Physiatrists

2017