naproxen has been researched along with bw-755c in 7 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (bw-755c) | Trials (bw-755c) | Recent Studies (post-2010) (bw-755c) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 462 | 0 | 0 |
| Protein | Taxonomy | naproxen (IC50) | bw-755c (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 3 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 2.4237 | |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | 5 | |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 5 | |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | 5 | |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | 5 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 5.5 | |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | 5 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 5.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kreft, AF; Musser, JH | 1 |
| Calhoun, W; Carlson, RP; Crossley, R; Datko, LJ; Dietrich, S; Heatherington, K; Marshall, LA; Meade, PJ; Opalko, A; Shepherd, RG | 1 |
| Besser, GM; Faria, MS; Grossman, AB; Navarra, P; Rees, LH; Tsagarakis, S | 1 |
| Kopeć, M; Maśliński, S; Stachurska, J; Wojtecka-Lukasik, E | 1 |
| Chaudhuri, G; Hayden, B; Soderberg, R; Zarem, H | 1 |
| Johnson, EA; Schwender, CF; Sircar, JC | 1 |
| Colombo, C; DiPasquale, G; Fryer, LR; Greenspan, PD; Haston, W; Healy, C; Kotyuk, B; Pastor, G; Pellas, TC; Raychaudhuri, A | 1 |
1 review(s) available for naproxen and bw-755c
| Article | Year |
|---|---|
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Diseases; Neutrophils; Quinolines | 1992 |
6 other study(ies) available for naproxen and bw-755c
| Article | Year |
|---|---|
Synthesis and antiinflammatory activity of certain 5,6,7,8-tetrahydroquinolines and related compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Male; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar | 1995 |
Interleukins-1 and -6 stimulate the release of corticotropin-releasing hormone-41 from rat hypothalamus in vitro via the eicosanoid cyclooxygenase pathway.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenocorticotropic Hormone; Animals; Benzeneacetamides; Corticotropin-Releasing Hormone; Cytokines; Eicosanoids; Hydroxamic Acids; Hypothalamus; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-6; Kinetics; Lipoxygenase Inhibitors; Male; Naproxen; Pituitary Gland; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Recombinant Proteins | 1991 |
Anti-inflammatory drugs modulate histamine release from mast cells induced by fibrinogen degradation products.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acetylcarnitine; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auranofin; Cells, Cultured; Dose-Response Relationship, Drug; Fibrin Fibrinogen Degradation Products; Guanidines; Histamine Release; Male; Mast Cells; Naproxen; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
Salvage of ischemic rabbit ear by BW-755C and steroids, but not by indomethacin.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Ear; Indomethacin; Ischemia; Methylprednisolone; Naproxen; Necrosis; Pyrazoles; Rabbits | 1987 |
Soybean lipoxygenase inhibition by nonsteroidal antiinflammatory drugs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Glycine max; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Naproxen; Piroxicam; Plants; Pyrazoles; Structure-Activity Relationship; Thiazines | 1983 |
LTB4-induced transient neutropenia in the rat: a model for evaluating efficacy and bioavailability of LTB4 receptor antagonists.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Dexamethasone; Hydroxyurea; Indomethacin; Leukocyte Count; Leukotriene B4; Male; Models, Biological; Naproxen; Neutropenia; Neutrophils; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene B4 | 1993 |