Compounds > naproxen
Page last updated: 2024-09-04

naproxen and avapro

naproxen has been researched along with avapro in 8 studies

Compound Research Comparison

Studies
(naproxen)		Trials
(naproxen)		Recent Studies (post-2010)
(naproxen)		Studies
(avapro)		Trials
(avapro)		Recent Studies (post-2010) (avapro)
4,5511,0571,4291,369385495

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)avapro (IC50)
Bile salt export pumpHomo sapiens (human)7.3067
Type-1 angiotensin II receptorHomo sapiens (human)0.0099
Type-2 angiotensin II receptorHomo sapiens (human)0.003

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Baekelandt, S; Beghin, M; Gillet, M; Kestemont, P; Mandiki, SNM; Nott, K; Robert, C; Ronkart, S; Schmitz, M1
Baekelandt, S; Beghin, M; Betoulle, S; Gillet, E; Kestemont, P; Mandiki, SNM; Nott, K; Palluel, O; Porcher, JM; Robert, C; Ronkart, S; Schmitz, M1

Reviews

1 review(s) available for naproxen and avapro

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for naproxen and avapro

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Environmentally-relevant mixture of pharmaceutical drugs stimulates sex-steroid hormone production and modulates the expression of candidate genes in the ovary of juvenile female rainbow trout.
    Aquatic toxicology (Amsterdam, Netherlands), 2018, Volume: 205

    Topics: Acetaminophen; Animals; Belgium; Carbamazepine; Diclofenac; Endocrine Disruptors; Female; Gene Expression Regulation; Gonadal Steroid Hormones; Irbesartan; Naproxen; Oncorhynchus mykiss; Ovary; Testosterone; Water Pollutants, Chemical

2018
Integrated multi-biomarker responses of juvenile rainbow trout (Oncorhynchus mykiss) to an environmentally relevant pharmaceutical mixture.
    Ecotoxicology and environmental safety, 2021, Sep-15, Volume: 221

    Topics: Acetaminophen; Animals; Belgium; Biomarkers; Brain; Carbamazepine; Diclofenac; Irbesartan; Liver; Lysosomes; Naproxen; Neurotoxicity Syndromes; Oncorhynchus mykiss; Rivers; Serotonin; Water Pollutants, Chemical

2021