Page last updated: 2024-09-04

naproxen and atb-346

naproxen has been researched along with atb-346 in 14 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(atb-346)
Trials
(atb-346)
Recent Studies (post-2010) (atb-346)
4,5511,0571,42918117

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (85.71)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Caliendo, G; Cirino, G; Santagada, V; Wallace, JL1
Blackler, R; Bolla, M; Ongini, E; Syer, S; Wallace, JL1
Ahmad, A; Campolo, M; Cuzzocrea, S; Di Paola, R; Esposito, E; Wallace, JL1
Blackler, RW; Elsheikh, W; Flannigan, KL; Wallace, JL1
Bilets'ka, LP; Bondarchuk, TI; Fomenko, IS; Panasiuk, NB; Skliarov, OIa1
Biletska, L; Bondarchuk, T; Fomenko, I; Panasyuk, N; Sklyarov, A; Wallace, JL1
Ahmad, A; Bruschetta, G; Campolo, M; Cordaro, M; Cuzzocrea, S; Di Paola, R; Esposito, E; Paterniti, I; Wallace, JL1
Gemici, B; Wallace, JL1
Bercik, P; Blackler, RW; Buret, AG; Da Silva, GJ; De Palma, G; Flannigan, KL; Manko, A; Surette, MG; Wallace, JL1
Agbor, TA; Chan, M; Cheadle, C; Devchand, P; Elsheikh, W; Flannigan, KL; Freydin, M; Ianaro, A; Kirkby, N; Mitchell, JA; Paul-Clark, M; Wallace, JL1
El Azhary, NM; Mostafa, DK; Nasra, RA1
de Nucci, G; Dicay, M; MacNaughton, WK; Vaughan, D; Wallace, JL1
Flint, JD; Gilroy, DW; Glanville, JRW; Hosin, AA; Jalali, P; Maini, AA; Patel, AA; Wallace, JL1
Caliendo, G; Corvino, A; Esposito, G; Fiorino, F; Frecentese, F; Magli, E; Migliaccio, M; Perissutti, E; Santagada, V; Scognamiglio, A; Severino, B; Sparaco, R1

Reviews

2 review(s) available for naproxen and atb-346

ArticleYear
Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic.
    Antioxidants & redox signaling, 2018, 06-01, Volume: 28, Issue:16

    Topics: Animals; Arthritis; Captopril; Cardiovascular Agents; Cardiovascular Diseases; Dose-Response Relationship, Drug; Humans; Hydrogen Sulfide; Naproxen

2018
H
    Biomolecules, 2021, 12-18, Volume: 11, Issue:12

    Topics: Animals; Benzenesulfonates; Chemistry, Pharmaceutical; Drug Discovery; Gasotransmitters; Humans; Hydrogen Sulfide; Morpholines; Naproxen; Organothiophosphorus Compounds

2021

Trials

1 trial(s) available for naproxen and atb-346

ArticleYear
Potent anti-inflammatory effects of an H
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Dinoprostone; Escherichia coli; Humans; Hydrogen Sulfide; Inflammation; Male; Middle Aged; Monocytes; Naproxen; Neutrophils; Pain; Phenotype; Solubility; Ultraviolet Rays; Vasoconstriction; Young Adult

2021

Other Studies

11 other study(ies) available for naproxen and atb-346

ArticleYear
Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346).
    British journal of pharmacology, 2010, Volume: 159, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gastric Mucosa; Hydrogen Sulfide; Hypertension; Intestinal Mucosa; Intestine, Small; Male; Mice; Molecular Structure; Naproxen; Rats; Rats, Wistar; Stomach Ulcer

2010
Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Drug Therapy, Combination; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Hypertension; Male; Naproxen; Nitrates; Obesity; Omeprazole; Pyrazoles; Rats; Rats, Inbred SHR; Rats, Wistar; Rats, Zucker; Sulfonamides

2012
A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:11

    Topics: Administration, Oral; Animals; Apoptosis; Cyclooxygenase Inhibitors; Cytokines; Hydrogen Sulfide; Locomotion; Male; Mice; Naproxen; Recovery of Function; Spinal Cord; Spinal Cord Injuries

2013
Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer.
    Nitric oxide : biology and chemistry, 2014, Sep-15, Volume: 41

    Topics: Aberrant Crypt Foci; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Colon; Colorectal Neoplasms; Dinoprostone; Male; Mice; Naproxen; Protective Agents; Rats; Thromboxane B2

2014
[Parameters of NO synthase system of gastric mucosa in rats under stress conditions and inhibition of cyclooxygenase].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2014, Volume: 60, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Female; Gastric Mucosa; Lipid Peroxidation; Naproxen; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stress, Physiological; Thiazolidines

2014
Effects of conventional and hydrogen sulfide-releasing non-steroidal anti-inflammatory drugs in rats with stress-induced and epinephrine-induced gastric damage.
    Stress (Amsterdam, Netherlands), 2014, Volume: 17, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Celecoxib; Disease Models, Animal; Epinephrine; Gastric Mucosa; Hydrogen Sulfide; Lipid Peroxidation; Male; Naproxen; Nitric Oxide; Nitric Oxide Synthase; Pyrazoles; Rats, Wistar; Restraint, Physical; Severity of Illness Index; Stomach Ulcer; Stress, Psychological; Sulfonamides

2014
Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice.
    Journal of neuroinflammation, 2014, Dec-04, Volume: 11

    Topics: Animals; Brain Injuries; Cerebral Cortex; Cyclooxygenase Inhibitors; Hydrogen Sulfide; Male; Mice; Motor Skills Disorders; Naproxen; Organ Size; Random Allocation

2014
Anti-inflammatory and cytoprotective properties of hydrogen sulfide.
    Methods in enzymology, 2015, Volume: 555

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Gastrointestinal Tract; Gene Expression Regulation; Humans; Hydrogen Sulfide; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Naproxen; Neurodegenerative Diseases; Pain; Protective Agents; Signal Transduction; Spinal Cord Injuries

2015
Deciphering the pathogenesis of NSAID enteropathy using proton pump inhibitors and a hydrogen sulfide-releasing NSAID.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Jun-15, Volume: 308, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hepatobiliary Elimination; Hydrogen Sulfide; Inflammation; Intestinal Diseases; Male; Naproxen; Proton Pump Inhibitors; Rats, Wistar; RNA, Ribosomal, 16S

2015
Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Adenomatous Polyposis Coli Protein; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Carcinogenesis; Chemoprevention; Colon; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hydrogen Sulfide; Intestinal Neoplasms; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Naproxen; Proto-Oncogene Proteins c-myc

2016
The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:7

    Topics: Allyl Compounds; Animals; Arginine; Cognitive Dysfunction; Hydrogen Sulfide; Inflammation; Inflammation Mediators; Male; Maze Learning; Naproxen; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Sulfides

2016