Page last updated: 2024-09-04

naproxen and arginine

naproxen has been researched along with arginine in 13 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(arginine)
Trials
(arginine)
Recent Studies (post-2010) (arginine)
4,5511,0571,42946,3881,68811,176

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)arginine (IC50)
Cationic amino acid transporter 3Homo sapiens (human)283

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's5 (38.46)29.6817
2010's7 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barzoi, G; De Santis, D; Finco, G; Gilli, E; Gottin, L; Ischia, S; Polati, E; Salgarelli, A1
Cirri, M; Maestrelli, F; Mura, P1
Davies, C; DeVoss, JJ; Gillam, EM; Graham, SE; Pearson, A; Scott, JR; Witham, K1
Bettinetti, GP; Catenacci, L; Cirri, M; Maestrelli, F; Mura, P; Sorrenti, M1
Berti, F; Brini, AT; Clement, MG; De Gennaro Colonna, V; Manfredi, B; Polvani, G; Rossoni, G1
Ain-Ai, A; Gupta, PK1
El Azhary, NM; Mostafa, DK; Nasra, RA1
Dengale, S; Grohganz, H; Kasten, G; Löbmann, K; Lobo, L; Rades, T1
Grohganz, H; Leopold, CS; Löbmann, K; Petry, I; Rades, T1

Reviews

1 review(s) available for naproxen and arginine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for naproxen and arginine

ArticleYear
[Management of postoperative pain in stomatology with ibuprofen L-arginine and naproxen].
    Minerva stomatologica, 1998, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Female; Humans; Ibuprofen; Informed Consent; Male; Middle Aged; Molar, Third; Naproxen; Pain, Postoperative; Tooth Extraction

1998

Other Studies

11 other study(ies) available for naproxen and arginine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Ternary systems of naproxen with hydroxypropyl-beta-cyclodextrin and aminoacids.
    International journal of pharmaceutics, 2003, Jul-24, Volume: 260, Issue:2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Amino Acids; Anti-Inflammatory Agents; Arginine; beta-Cyclodextrins; Calorimetry, Differential Scanning; Cyclodextrins; Hydrogen-Ion Concentration; Isoleucine; Lysine; Microscopy, Electron, Scanning; Naproxen; Solubility; Valine

2003
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4

    Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity

2004
Solid-state characterization and dissolution properties of naproxen-arginine-hydroxypropyl-beta-cyclodextrin ternary system.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2005, Volume: 59, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Arginine; beta-Cyclodextrins; Chemistry, Pharmaceutical; Naproxen; Solubility; X-Ray Diffraction

2005
Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats.
    Pharmacological research, 2006, Volume: 53, Issue:4

    Topics: Animals; Arginine; Arrhythmias, Cardiac; Cardiotonic Agents; Creatine Kinase; Epoprostenol; Isosorbide Dinitrate; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Naproxen; Nitric Oxide; Peroxidase; Polydeoxyribonucleotides; Random Allocation; Rats; Rats, Wistar; Thromboxane B2

2006
Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound.
    International journal of pharmaceutics, 2008, Mar-03, Volume: 351, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cellulose; Drug Stability; Drug Storage; Excipients; Freeze Drying; Nanoparticles; Naproxen; Particle Size; Solubility; Suspensions; Time Factors

2008
The hydrogen sulfide releasing compounds ATB-346 and diallyl trisulfide attenuate streptozotocin-induced cognitive impairment, neuroinflammation, and oxidative stress in rats: involvement of asymmetric dimethylarginine.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:7

    Topics: Allyl Compounds; Animals; Arginine; Cognitive Dysfunction; Hydrogen Sulfide; Inflammation; Inflammation Mediators; Male; Maze Learning; Naproxen; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Sulfides

2016
In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 132

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Male; Naproxen; Rats; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Transition Temperature; Vitrification; X-Ray Diffraction

2018
In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium - A proof of concept study.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 133

    Topics: Arginine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Citric Acid; Furosemide; Hydrolysis; Indomethacin; Methylmethacrylates; Naproxen; Proof of Concept Study; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; X-Ray Diffraction

2018