naproxen has been researched along with arachidonic acid in 36 studies
Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (arachidonic acid) | Trials (arachidonic acid) | Recent Studies (post-2010) (arachidonic acid) |
---|---|---|---|---|---|
4,551 | 1,057 | 1,429 | 19,295 | 486 | 3,040 |
Protein | Taxonomy | naproxen (IC50) | arachidonic acid (IC50) |
---|---|---|---|
60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
Fatty acid-binding protein, adipocyte | Homo sapiens (human) | 2.75 | |
10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
60 kDa chaperonin | Escherichia coli | 7.3 | |
10 kDa chaperonin | Escherichia coli | 7.3 | |
Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.0715 | |
Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.6026 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 15 (41.67) | 18.7374 |
1990's | 9 (25.00) | 18.2507 |
2000's | 7 (19.44) | 29.6817 |
2010's | 3 (8.33) | 24.3611 |
2020's | 2 (5.56) | 2.80 |
Authors | Studies |
---|---|
Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T | 1 |
Bendele, AM; Benslay, DN; Hom, JT; Lee, SJ; Lindstrom, TD; Naismith, RW; Ruterbories, KJ; Spaethe, SM | 1 |
Bachetti, T; Bucolo, C; Canossa, M; Mangiafico, S; Marino, A; Spampinato, S | 1 |
Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC | 1 |
Stokes, JB | 1 |
Boyle, EA; Crummey, A; Harper, GP; Mangan, FR | 1 |
Audette, CA; Burstein, SH; Doyle, SA; Hull, K; Hunter, SA; Latham, V | 1 |
Bennett, A; Capasso, F; Tavares, IA; Vine, ND | 1 |
Kothari, HV; Ku, EC; Lee, W; Scholer, DW | 1 |
Foidart, JB; Mahieu, P | 1 |
Griswold, DE; Hanna, N; Schwartz, L; Webb, E | 1 |
Gustafson, GT; Lerner, UH | 1 |
Delbridge, L; Handelsman, DJ; McLennan, S; Reeve, T; Turtle, JR; Yue, DK | 1 |
Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J | 1 |
Kimble, EF; Kothari, H; Ku, EC; Lee, W; Liauw, LH | 1 |
Chamberlain, PD; Nunn, B | 1 |
Ballaron, SJ; Bedord, CJ; De Young, LM; Spires, DA; Wagner, B; Young, JM | 1 |
Whittle, BJ | 1 |
Dunham, EW; Sakr, HM | 1 |
Breton, J; Griswold, DE; Marshall, PJ; Torphy, TJ; Webb, EF; White, JR | 1 |
Barbacane, RC; Bartle, L; Conti, P; Reale, M; Sipe, JD | 1 |
Fraser, L; Larkin, SW; Showell, HJ; Warren, JB; Williams, TJ | 1 |
Ogg, CL; Stanley-Samuelson, DW | 1 |
Mue, S; Ohuchi, K; Watanabe, M; Yamada, M | 1 |
Jurenka, RA; Stanley, DW; Tunaz, H | 1 |
Backhouse, N; Bórquez, J; Delporte, C; Loyola, A; Salinas, P; San-Martín, A | 1 |
Gross, GJ; Moore, J | 1 |
Guévremont, M; Laufer, S; Marcouiller, P; Martel-Pelletier, J; Pelletier, JP; Ranger, P; Reboul, P | 1 |
Bronckaers, A; Claeys, I; De Loof, A; Franssens, V; Simonet, G; Vanden Broeck, J | 1 |
Anzellotti, P; Capone, ML; Di Francesco, L; Di Gregorio, P; Merciaro, G; Patrignani, P; Sciulli, MG; Tacconelli, S | 1 |
Barrett, TD; Hong, TT; Huang, J; Lucchesi, BR | 1 |
Anzellotti, P; Bruno, A; Capone, ML; Di Francesco, L; Di Gregorio, P; Garcia Rodriguez, LA; Grossi, L; Jeyam, A; Merciaro, G; Patrignani, P; Price, TS; Renda, G; Tacconelli, S; Tontodonati, P | 1 |
Dong, L; Jurban, BJ; Sharma, NP; Smith, WL | 1 |
Alaseem, AM; Aldebeyan, SA; Antoniou, J; Madiraju, P; Mwale, F; Noorwali, H | 1 |
Barceló, D; López-Doval, JC; Rodríguez-Mozaz, S; Sabater, S; Serra-Compte, A | 1 |
Eleftheriou, P; Gavalas, A; Geronikaki, A; Haroun, M; Kamoutsis, C; Kochkar, H; Nair, AB; Paparisva, A; Petrou, A; Tratrat, C; Venugopala, KN | 1 |
3 trial(s) available for naproxen and arachidonic acid
Article | Year |
---|---|
Prolonged microvascular vasodilation induced by leukotriene B4 in human skin is cyclooxygenase independent.
Topics: Administration, Oral; Administration, Topical; Adult; Arachidonic Acid; Dose-Response Relationship, Drug; Erythema; Humans; Indoles; Indomethacin; Leukotriene B4; Male; Microcirculation; Naproxen; Oxindoles; Regional Blood Flow; Skin; Vasodilation | 1995 |
Human pharmacology of naproxen sodium.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Humans; Lipopolysaccharides; Monocytes; Naproxen; Platelet Aggregation; Thromboxane B2 | 2007 |
Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Naproxen; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Reference Values; Thromboxane B2; Young Adult | 2011 |
33 other study(ies) available for naproxen and arachidonic acid
Article | Year |
---|---|
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep | 1998 |
Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Experimental; Collagen; Diamines; Diclofenac; Dinoprostone; Disease Models, Animal; Female; Interleukin-1; Leukotriene B4; Male; Naproxen; Oxazines; Phenols; Piroxicam; Rats; Rats, Inbred Lew; Thromboxane B2 | 1992 |
Effects of sodium naproxen eye drops on rabbit ocular inflammation induced by sodium arachidonate.
Topics: Animals; Arachidonic Acid; Conjunctivitis; Dinoprostone; Eye; Eye Proteins; Intraocular Pressure; Iritis; Leukotriene B4; Male; Naproxen; Neutrophils; Ophthalmic Solutions; Rabbits | 1991 |
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E | 1990 |
Modulation of vasopressin-induced water permeability of the cortical collecting tubule by endogenous and exogenous prostaglandins.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Body Water; Cell Membrane Permeability; Epithelium; Kidney Cortex; Kidney Tubules; Kinetics; Meclofenamic Acid; Naproxen; Prostaglandins; Rabbits; Vasopressins | 1985 |
Inhibition of arachidonic acid-induced ear oedema as a model for assessing topical anti-inflammatory compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Edema; Free Radicals; Histamine Release; Indomethacin; Lipoxygenase Inhibitors; Mast Cells; Mathematics; Mice; Naproxen | 1987 |
Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cannabinoids; Dronabinol; Edema; Female; Hydroxyeicosatetraenoic Acids; Mice; Naproxen; Platelet Activating Factor; Structure-Activity Relationship | 1989 |
Effects of isoxicam and other non-steroidal anti-inflammatory drugs on arachidonic acid metabolism by rat peritoneal leucocytes.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Leukocytes; Male; Naproxen; Piroxicam; Prostaglandins; Rats; Rats, Inbred Strains; Thiazines | 1985 |
Effect of diclofenac sodium on the arachidonic acid cascade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides | 1986 |
Glomerular mesangial cell contractility in vitro is controlled by an angiotensin-prostaglandin balance.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Fluorescent Antibody Technique; Glomerular Mesangium; Indomethacin; Lipoxygenase Inhibitors; Microscopy, Phase-Contrast; Naproxen; Prostaglandins; Prostaglandins E; Pyrazoles; Rats; Receptors, Angiotensin | 1986 |
Arachidonic acid-induced inflammation: inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Ibuprofen; Imidazoles; Inflammation; Male; Masoprocol; Mice; Mice, Inbred BALB C; Naproxen; Peritonitis; Piroxicam; Pyrazoles; Thiazoles | 1987 |
Blood coagulation and bone metabolism: some characteristics of the bone resorptive effect of thrombin in mouse calvarial bones in vitro.
Topics: Adrenal Cortex Hormones; Animals; Arachidonic Acid; Arachidonic Acids; Bone and Bones; Bone Matrix; Bone Resorption; Calcitonin; Calcium; In Vitro Techniques; Indomethacin; Inflammation; Lactates; Lysosomes; Meclofenamic Acid; Mice; Naproxen; Phosphates; Rats; Thrombin | 1988 |
The effects of cyclooxygenase and lipoxygenase inhibitors on the collagen abnormalities of diabetic rats.
Topics: Acetaminophen; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Female; Indomethacin; Lipoxygenase Inhibitors; Naproxen; Rats; Rats, Inbred Strains | 1985 |
The effects of diclofenac sodium on arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides | 1985 |
Effects of diclofenac sodium on arachidonic acid metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Diclofenac; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Monocytes; Naproxen; Neutrophils; Piroxicam; SRS-A; Thiazines | 1985 |
Effect of nabumetone (BRL 14777), a new anti-inflammatory drug, on human platelet reactivity ex vivo: comparison with naproxen.
Topics: Adenosine Diphosphate; Adult; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Female; Humans; Male; Naproxen; Platelet Adhesiveness; Platelet Aggregation | 1982 |
The mouse ear inflammatory response to topical arachidonic acid.
Topics: Administration, Topical; Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; DNA; Dose-Response Relationship, Drug; Ear, External; Edema; Erythema; Female; Inflammation; Mice; Naproxen; Prostaglandin-Endoperoxide Synthases; Skin; Vasodilation | 1984 |
Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Digestive System; Flurbiprofen; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Ketoprofen; Naproxen; Prostaglandins; Rats | 1981 |
Enhanced renal vasoconstriction in rats fed essential fatty acid-deficient diet.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Fatty Acids, Essential; Indomethacin; Kidney; Male; Naproxen; Norepinephrine; Rats; Rats, Inbred Strains; Regional Blood Flow; Vascular Resistance; Vasoconstriction | 1982 |
Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Ear, External; Eicosanoids; Histamine Release; Humans; Imidazoles; Inflammation; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Monocytes; Nadolol; Naproxen; Neutrophils; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrazoles; Pyrrolidinones; Receptors, Adrenergic, beta; Rolipram; SRS-A; Thiazoles | 1993 |
The down-regulation of IL-6-stimulated fibrinogen steady state mRNA and protein levels by human recombinant IL-1 is not PGE2-dependent: effects of IL-1 receptor antagonist (IL-1RA).
Topics: Arachidonic Acid; Carcinoma, Hepatocellular; Dinoprostone; Down-Regulation; Fibrinogen; Gene Expression; Humans; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Naproxen; Phospholipases A; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Tumor Cells, Cultured | 1995 |
Prostaglandin biosynthesis by fat body from the tobacco hornworm, Manduca sexta.
Topics: Animals; Arachidonic Acid; Fat Body; Hydroxyeicosatetraenoic Acids; Indomethacin; Larva; Microsomes; Moths; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins A; Temperature | 1994 |
Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Ibuprofen; Indomethacin; Macrophages, Peritoneal; Male; Naproxen; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Fat Body; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Indomethacin; Microsomes; Moths; Naproxen; Prostaglandin D2; Prostaglandins; Prostaglandins A; Temperature | 2001 |
Pharmaco-toxicological study of diterpenoids.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apiaceae; Arachidonic Acid; Chile; Diterpenes; Dose-Response Relationship, Drug; Edema; Female; Indicators and Reagents; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Molecular Conformation; Naproxen; Pain Measurement; Plants, Medicinal; Structure-Activity Relationship; Sulfonamides; Tetradecanoylphorbol Acetate | 2003 |
Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine.
Topics: Acetylcholine; Animals; Arachidonic Acid; Blood Pressure; Coronary Circulation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Isoenzymes; Lipopolysaccharides; Male; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2; Vasodilation; Vasodilator Agents | 2004 |
Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
Topics: Acetates; Aged; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipopolysaccharides; Male; Masoprocol; Naproxen; Osteoarthritis, Knee; Pyrroles; Signal Transduction; Synovial Membrane | 2005 |
Eicosanoids mediate the laminarin-induced nodulation response in larvae of the flesh fly, Neobellieria bullata.
Topics: Animals; Arachidonic Acid; Bacillus thuringiensis; Dexamethasone; Diptera; Dose-Response Relationship, Drug; Eicosanoids; Escherichia coli; Glucans; Immunity, Innate; Larva; Microscopy; Naproxen; Polysaccharides; Saccharomyces cerevisiae; Umbelliferones | 2005 |
Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.
Topics: Acetylcholine; Animals; Arachidonic Acid; Benzofurans; Carotid Arteries; Coronary Circulation; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Epoprostenol; Inflammation; Ligation; Lipopolysaccharides; Naproxen; Platelet Aggregation; Propionates; Pyrazoles; Receptors, Epoprostenol; Sulfonamides; Thrombosis; Time Factors; Vasodilation; Vasodilator Agents | 2008 |
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides | 2013 |
Naproxen induces type X collagen expression in human bone-marrow-derived mesenchymal stem cells through the upregulation of 5-lipoxygenase.
Topics: Aged; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bone Marrow Cells; Collagen Type X; Core Binding Factor Alpha 1 Subunit; Enzyme Activation; Female; Humans; Male; Mesenchymal Stem Cells; Middle Aged; Mitogen-Activated Protein Kinases; Models, Biological; Naproxen; Osteoarthritis; Phosphorylation; Protein Kinase Inhibitors; Up-Regulation | 2015 |
Diet quality and NSAIDs promote changes in formation of prostaglandins by an aquatic invertebrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Diclofenac; Diet; Ibuprofen; Invertebrates; Ketoprofen; Lipid Metabolism; Naproxen; Prostaglandins | 2020 |
New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Female; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Molecular Docking Simulation; Naproxen; Structure-Activity Relationship; Triazoles | 2021 |