Page last updated: 2024-09-04

naproxen and apixaban

naproxen has been researched along with apixaban in 3 studies

Compound Research Comparison

Studies (naproxen)	Trials (naproxen)	Recent Studies (post-2010) (naproxen)	Studies (apixaban)	Trials (apixaban)	Recent Studies (post-2010) (apixaban)
4,551	1,057	1,429	2,405	255	2,250

Protein Interaction Comparison

Protein	Taxonomy	naproxen (IC50)	apixaban (IC50)
Coagulation factor X	Homo sapiens (human)		0.22

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Balimane, PV; Frost, CE; Gan, J; Han, YH; He, K; Herbst, JJ; Humphreys, WG; Kolb, J; Shou, W; Wang, L; Zhang, D	1
Barrett, YC; Boyd, RA; Byon, W; Frost, C; Gandhi, MD; LaCreta, F; Pursley, J; Shenker, A; Wang, J; Zhang, D	1

Trials

1 trial(s) available for naproxen and apixaban

Article	Year
Evaluation of the effect of naproxen on the pharmacokinetics and pharmacodynamics of apixaban. British journal of clinical pharmacology, 2014, Volume: 78, Issue:4 Topics: Adult; Drug Interactions; Factor Xa Inhibitors; Female; Humans; International Normalized Ratio; Male; Naproxen; Pyrazoles; Pyridones	2014

Other Studies

2 other study(ies) available for naproxen and apixaban

Article	Year
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Characterization of efflux transporters involved in distribution and disposition of apixaban. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4 Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line, Transformed; Cell Membrane Permeability; Cyclosporine; Digoxin; Diketopiperazines; Dose-Response Relationship, Drug; Drug Interactions; Fibrinolytic Agents; Heterocyclic Compounds, 4 or More Rings; Humans; Ketoconazole; Male; Naproxen; Neoplasm Proteins; Pyrazoles; Pyridones; Rats	2013

Article

Year

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.

Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023

Characterization of efflux transporters involved in distribution and disposition of apixaban.

Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line, Transformed; Cell Membrane Permeability; Cyclosporine; Digoxin; Diketopiperazines; Dose-Response Relationship, Drug; Drug Interactions; Fibrinolytic Agents; Heterocyclic Compounds, 4 or More Rings; Humans; Ketoconazole; Male; Naproxen; Neoplasm Proteins; Pyrazoles; Pyridones; Rats

2013