Page last updated: 2024-09-04

naproxen and amoxicillin

naproxen has been researched along with amoxicillin in 37 studies

Compound Research Comparison

Studies
(naproxen)
Trials
(naproxen)
Recent Studies (post-2010)
(naproxen)
Studies
(amoxicillin)
Trials
(amoxicillin)
Recent Studies (post-2010) (amoxicillin)
4,5511,0571,42910,9152,6613,467

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.70)18.7374
1990's4 (10.81)18.2507
2000's6 (16.22)29.6817
2010's24 (64.86)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bourgeois, V; Depierreux, M; Ducobu, J; Dupont, P; Nortier, J1
Bourgeois, V; Depierreux, M; Dupont, P; Nortier, J1
Grossman, JE; Varsano, IB; Volovitz, BM1
Lapière, CM; Nusgens, BV; Paquet, P; Piérard, GE1
Schretter-Irschick, E; Yayan, J1
Acero, JL; Benitez, FJ; Real, FJ; Roldan, G1
Domínguez-Pérez, Á; Iribarren-Marín, Mdel A; Martín-García, C; Pérez-Vega, H1
Acero, JL; Benitez, FJ; Casas, F; Real, FJ; Roldan, G1
Escribano, E; Navarro, CR; Regué, JQ; Sala, XG; Salamanca, J1
Feo-Brito, F; Herreros, B; Méndez, Y; Urra, JM1
Cristina, RH; María Jesús, MV; Miguel Ángel, BL; Rut, FT1
Bello-López, MÁ; López-Pérez, G; Martín-Valero, MJ; Román-Hidalgo, C1
Horikoshi, Y; Miura, M; Uda, K1
Chen, Y; Li, L; Zheng, S1
Hassib, ST; Mostafa, EA; Sharf, MG; Taha, EA1
Banerjee, A; Castelletto, V; Chatterjee, A; Das, S; Gachhui, R; Hamley, IW; Hansda, B; Kumar, S; Majumder, J; Mondal, B; Sen, P1

Reviews

1 review(s) available for naproxen and amoxicillin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for naproxen and amoxicillin

ArticleYear
Effect of naproxen, a prostaglandin inhibitor, on acute otitis media and persistence of middle ear effusion in children.
    The Annals of otology, rhinology, and laryngology, 1989, Volume: 98, Issue:5 Pt 1

    Topics: Acute Disease; Amoxicillin; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Naproxen; Otitis Media with Effusion; Prostaglandin Antagonists; Random Allocation

1989

Other Studies

35 other study(ies) available for naproxen and amoxicillin

ArticleYear
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
    Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25

    Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship

1998
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Progression of a naproxen and amoxicillin induced acute interstitial nephritis with nephrotic syndrome: case report.
    Clinical nephrology, 1991, Volume: 35, Issue:5

    Topics: Adult; Amoxicillin; Biopsy; Humans; Kidney; Kidney Failure, Chronic; Male; Naproxen; Nephritis, Interstitial; Nephrotic Syndrome; Pneumonia

1991
Acute interstitial nephritis with nephrotic syndrome after intake of naproxen and amoxycillin.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1990, Volume: 5, Issue:12

    Topics: Adult; Amoxicillin; Humans; Male; Naproxen; Nephritis, Interstitial; Nephrotic Syndrome

1990
Gelatinases in drug-induced toxic epidermal necrolysis.
    European journal of clinical investigation, 1998, Volume: 28, Issue:7

    Topics: Adult; Aged; Amoxicillin; Biopsy; Blister; Child, Preschool; Collagenases; Enzyme Activation; Female; Gelatinases; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Middle Aged; Naproxen; Phenytoin; Piroxicam; Stevens-Johnson Syndrome

1998
Localized episcleritis-like lesions on both eyes in a patient with para nasal sinusitis.
    International ophthalmology, 2008, Volume: 28, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Maxillary Sinusitis; Naproxen; Scleritis

2008
Kinetics of aqueous chlorination of some pharmaceuticals and their elimination from water matrices.
    Water research, 2010, Volume: 44, Issue:14

    Topics: Amoxicillin; Fresh Water; Halogenation; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Naproxen; Pharmaceutical Preparations; Phenacetin; Water Pollutants, Chemical; Water Purification

2010
[Spondylodiscitis caused by Streptococcus pneumonia associated with an infected abdominal aortic aneurysm].
    Enfermedades infecciosas y microbiologia clinica, 2011, Volume: 29, Issue:4

    Topics: Alcoholism; Amoxicillin; Aneurysm, Infected; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aortic Aneurysm, Abdominal; Aortitis; Blood Vessel Prosthesis Implantation; Combined Modality Therapy; Discitis; Disease Susceptibility; Humans; Lumbar Vertebrae; Male; Middle Aged; Naproxen; Pneumococcal Infections; Psoas Abscess; Pulmonary Disease, Chronic Obstructive; Rifampin; Tomography, X-Ray Computed

2011
Bromination of selected pharmaceuticals in water matrices.
    Chemosphere, 2011, Volume: 85, Issue:9

    Topics: Amoxicillin; Halogenation; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Naproxen; Pharmaceutical Preparations; Phenacetin; Water Pollutants, Chemical

2011
Single-pass intestinal perfusion to establish the intestinal permeability of model drugs in mouse.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Amoxicillin; Animals; Furosemide; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Models, Animal; Naproxen; Perfusion; Permeability; Pharmaceutical Preparations; Piroxicam; Ranitidine; Rats

2012
Usefulness of basophil activation test for the diagnosis of IgE mediated hypersensitivity to tetanus toxoid vaccine.
    Journal of immunological methods, 2018, Volume: 454

    Topics: Aged, 80 and over; Allergens; Amoxicillin; Anaphylaxis; Basophils; Cell Degranulation; Cells, Cultured; Diagnosis, Differential; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Immunologic Tests; Male; Naproxen; Tetanus Toxoid; Wounds, Stab

2018
Use of Polymer Inclusion Membranes (PIMs) as support for electromembrane extraction of non-steroidal anti-inflammatory drugs and highly polar acidic drugs.
    Talanta, 2018, Mar-01, Volume: 179

    Topics: Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Electrochemical Techniques; Hippurates; Ibuprofen; Ketoprofen; Membranes, Artificial; Naproxen; Niacin; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Salicylic Acid

2018
Chitosan tailor-made membranes as biopolymeric support for electromembrane extraction.
    Talanta, 2019, Jul-01, Volume: 199

    Topics: Amoxicillin; Biopolymers; Chitosan; Electrochemical Techniques; Hippurates; Humans; Ibuprofen; Ketoprofen; Naproxen; Niacin; ortho-Aminobenzoates; Salicylic Acid

2019
Prolonged PR interval in a patient with acute rheumatic fever.
    QJM : monthly journal of the Association of Physicians, 2019, Oct-01, Volume: 112, Issue:10

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Atrioventricular Block; Child, Preschool; Electrocardiography; Humans; Male; Naproxen; Rheumatic Fever; Rheumatic Heart Disease; Treatment Outcome

2019
Stevens-Johnson syndrome and acute vanishing bile duct syndrome after the use of amoxicillin and naproxen in a child.
    The Journal of international medical research, 2019, Volume: 47, Issue:9

    Topics: Amoxicillin; Bile Ducts; Child; Humans; Liver; Male; Naproxen; Stevens-Johnson Syndrome; Syndrome

2019
RP-HPLC-DAD Method Development and Validation for Simultaneous Determination of Lansoprazole, Tinidazole, Amoxicillin, and Naproxen in Their Raw Materials and Combined Dosage Form: DOE Approach for Optimization of the Proposed Method.
    Journal of AOAC International, 2022, Apr-27, Volume: 105, Issue:3

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Metronidazole; Naproxen; Omeprazole; Research Design; Tinidazole

2022
Histidine-Containing Amphiphilic Peptide-Based Non-Cytotoxic Hydrogelator with Antibacterial Activity and Sustainable Drug Release.
    Langmuir : the ACS journal of surfaces and colloids, 2023, 05-30, Volume: 39, Issue:21

    Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Drug Liberation; Escherichia coli; Histidine; Hydrogels; Mice; Naproxen; Peptides; Staphylococcus aureus

2023