naproxen has been researched along with 6-methoxy-2-naphthylacetic acid in 10 studies
| Studies (naproxen) | Trials (naproxen) | Recent Studies (post-2010) (naproxen) | Studies (6-methoxy-2-naphthylacetic acid) | Trials (6-methoxy-2-naphthylacetic acid) | Recent Studies (post-2010) (6-methoxy-2-naphthylacetic acid) |
|---|---|---|---|---|---|
| 4,551 | 1,057 | 1,429 | 61 | 6 | 13 |
| Protein | Taxonomy | naproxen (IC50) | 6-methoxy-2-naphthylacetic acid (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 4.113 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 0.65 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 1.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freeman, PC; Gaster, LM; Goudie, AC; Hughes, BO; Lake, AW; Miller, D; Rose, CJ | 1 |
| David, KC; Delgado, P; Graff, G; Haggard, KS; Hellberg, MR; Kessler, TL; Namil, A; Nixon, JC | 1 |
| Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
| Adeniji, A; Marnett, LJ; Penning, TM; Tamae, D; Uddin, MJ; Wangtrakuldee, P; Zang, T | 1 |
| Barradas, MA; Dandona, P; Jeremy, JY; Kirk, RM; Mikhailidis, DP | 2 |
| Dandona, P; Jeremy, JY; Mikhailidis, DP; Thompson, CS | 1 |
| Clarke, GD; MacPherson, IS; Petrone, G; Spangler, RS | 1 |
| Goto, T; Matsumoto, H; Mikami, E; Nishida, M; Ohno, T | 1 |
| Eriksson, LA; Musa, KA | 1 |
10 other study(ies) available for naproxen and 6-methoxy-2-naphthylacetic acid
| Article | Year |
|---|---|
4-(6-Methoxy-2-naphthyl)butan-2-one and related analogues, a novel structural class of antiinflammatory compounds.
Topics: Animals; Anti-Inflammatory Agents; Female; Gossypium; Granuloma; Naphthalenes; Rats; Structure-Activity Relationship | 1978 |
Novel esters and amides of nonsteroidal antiinflammatory carboxylic acids as antioxidants and antiproliferative agents.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carboxylic Acids; Cattle; Cell Division; Cells, Cultured; Child, Preschool; DNA; Endothelium, Vascular; Esters; Female; Humans; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Molecular Structure | 1999 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Butyrates; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Structure; Naphthalenes; Structure-Activity Relationship | 2016 |
Effects of the prodrug nabumetone, and its active metabolite, 6-MNA, on human and rat gastric mucosal prostanoids and platelet function.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Butanones; Dinoprostone; Epoprostenol; Gastric Mucosa; Humans; Indomethacin; Male; Nabumetone; Naphthaleneacetic Acids; Naproxen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prodrugs; Rats; Rats, Inbred Strains | 1990 |
The effect of nabumetone and its principal active metabolite on in vitro human gastric mucosal prostanoid synthesis and platelet function.
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Butanones; Culture Techniques; Dinoprostone; Epoprostenol; Gastric Mucosa; Humans; Indomethacin; Nabumetone; Naphthaleneacetic Acids; Naproxen; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 1990 |
Effect of the antiinflammatory prodrug, nabumetone and its principal active metabolite on rat gastric mucosal, aortic and platelet eicosanoid synthesis, in vitro and ex vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Blood Platelets; Butanones; Eicosanoids; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Nabumetone; Naphthaleneacetic Acids; Naproxen; Prodrugs; Rats; Rats, Inbred Strains | 1990 |
Antinociceptive effects of non-steroidal anti-inflammatory drugs in a rat model of unilateral hindpaw inflammation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Inflammation; Injections, Intramuscular; Male; Naphthaleneacetic Acids; Naproxen; Pain; Rats; Rats, Wistar | 1994 |
Simultaneous analysis of naproxen, nabumetone and its major metabolite 6-methoxy-2-naphthylacetic acid in pharmaceuticals and human urine by high-performance liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Nabumetone; Naphthaleneacetic Acids; Naproxen; Reference Standards; Spectrophotometry, Ultraviolet | 2000 |
Theoretical study of the phototoxicity of naproxen and the active form of nabumetone.
Topics: Computer Simulation; Models, Chemical; Molecular Structure; Naphthaleneacetic Acids; Naproxen; Oxidation-Reduction; Photochemistry; Photosensitizing Agents; Quantum Theory | 2008 |