Compounds > naproxen
Page last updated: 2024-09-04

naproxen and 1-methyl-3-isobutylxanthine

naproxen has been researched along with 1-methyl-3-isobutylxanthine in 5 studies

Compound Research Comparison

Studies
(naproxen)		Trials
(naproxen)		Recent Studies (post-2010)
(naproxen)		Studies
(1-methyl-3-isobutylxanthine)		Trials
(1-methyl-3-isobutylxanthine)		Recent Studies (post-2010) (1-methyl-3-isobutylxanthine)
4,5511,0571,4295,1485279

Protein Interaction Comparison

ProteinTaxonomynaproxen (IC50)1-methyl-3-isobutylxanthine (IC50)
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7AHomo sapiens (human)8.1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)31
Chain A, Phosphodiesterase 9AHomo sapiens (human)500
Chain A, Class I phosphodiesterase PDEB1Leishmania major580
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)698
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)40
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AHomo sapiens (human)117.2
Phosphodiesterase Bos taurus (cattle)9.9
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)4
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1667
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Bos taurus (cattle)9.9
Adenosine receptor A1Rattus norvegicus (Norway rat)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1AHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BBos taurus (cattle)9.9
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BHomo sapiens (human)3.4
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)0.242
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CHomo sapiens (human)3.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)7
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)0.1
Phosphodiesterase Rattus norvegicus (Norway rat)0.1

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stokes, JB1
Christensen, S; Dousa, TP; Homma, S; Kusano, E; Murayama, N; Werness, JL; Yusufi, AN1
Franki, N; Hays, RM; Mosenkis, B1
Hoch, BS; Lipner, HI; Louis, BM; Shahmehdi, SJ1
Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P1

Other Studies

5 other study(ies) available for naproxen and 1-methyl-3-isobutylxanthine

ArticleYear
Modulation of vasopressin-induced water permeability of the cortical collecting tubule by endogenous and exogenous prostaglandins.
    Mineral and electrolyte metabolism, 1985, Volume: 11, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Arachidonic Acids; Body Water; Cell Membrane Permeability; Epithelium; Kidney Cortex; Kidney Tubules; Kinetics; Meclofenamic Acid; Naproxen; Prostaglandins; Rabbits; Vasopressins

1985
Effects of calcium on the vasopressin-sensitive cAMP metabolism in medullary tubules.
    The American journal of physiology, 1985, Volume: 249, Issue:6 Pt 2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Arginine Vasopressin; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ibuprofen; Kidney Tubules; Kidney Tubules, Collecting; Male; Naproxen; Rats; Rats, Inbred Strains; Rotenone; Vasopressins

1985
Evidence that monensin inhibits vasopressin-stimulated water flow at an early step in the receptor-adenylate cyclase sequence.
    Biology of the cell, 1989, Volume: 66, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Body Water; Bufo marinus; Colforsin; In Vitro Techniques; Kinetics; Monensin; Naproxen; Receptors, Angiotensin; Receptors, Vasopressin; Urinary Bladder; Vasopressins

1989
Foscarnet alters antidiuretic hormone-mediated transport.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Antiviral Agents; Biological Transport, Active; Bufo marinus; Cyclooxygenase Inhibitors; Female; Foscarnet; In Vitro Techniques; Naproxen; Phosphodiesterase Inhibitors; Urinary Bladder; Vasopressins

1995
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors

2005