naphthoquinones has been researched along with zephiramine* in 2 studies
2 other study(ies) available for naphthoquinones and zephiramine
| Article | Year |
|---|---|
Study of the sensitization of tetradecyl benzyl dimethyl ammonium chloride for the color development reaction between lysine and sodium 1,2-naphthoquinone-4-sulfonate and the determination of lysine in pharmaceutical and biological samples.
A rapid, simple and sensitive method for the determination of lysine (Lys) using sodium 1,2-naphthoquinone-4-sulfonate (NQS) and tetradecyl benzyl dimethyl ammonium chloride (Zeph) is presented in this paper. The method is based on the russety product formed from Lys, NQS and Zeph in a buffer solution of pH 9.60, and the stoichiometric ratio of the product is 1:2:2. Beer's law is obeyed in a range of 0.09-18 microg ml(-1) of Lys at the maximum absorption of 474 nm (epsilon(474) is 8.1 x 10(5)l mol(-1)cm(-1)). The equation of linear regression is A=0.40427+0.06112C, with a linearly correlation coefficient of 0.9972. The limit of detection is 0.07 microg ml(-1), R.S.D. 0.8%, and average recovery rate in a range of 98.9-100.1%. This paper further optimizes the determination of Lys compared with the previous methods, and the reaction mechanism is studied intensively. The proposed method has been successfully applied to the determination of Lys in pharmaceutical and biological samples. The common components as nutritional additives in pharmaceuticals and other compounds in biological samples nearly do not interfere with the proposed method. Topics: Benzalkonium Compounds; Body Fluids; Buffers; Calibration; Colorimetry; Humans; Hydrogen-Ion Concentration; Lysine; Naphthoquinones; Pharmaceutical Preparations; Solutions; Solvents; Spectrum Analysis | 2007 |
Study of the sensitization of tetradecyl benzyl dimethyl ammonium chloride for spectrophotometric determination of dopamine hydrochloride using sodium 1,2-naphthoquinone-4-sulfonate as the chemical derivative chromogenic reagent.
A new method has been established for the determination of dopamine hydrochloride (DPH) using sodium 1,2-naphthoquinone-4-sulfonate (NQS) and tetradecyl benzyl dimethyl ammonium chloride (Zeph). This method is based on the formation of a pink compound from the reaction of DPH, sodium 1,2-naphthoquinone-4-sulfonate and Zeph. The condensation reaction proceeds quantitatively in pH 9.40 buffer solution. The maximum absorption wavelength and the value of epsilon491 were 491 nm, and 7.51x10(3) l mol(-1) cm(-1), respectively, when the stoichiometric ratio of the reaction was 1:1:1. Beer's law was obeyed in the range of 0.16-40 mg l(-1) of DPH. The data have been filled to a linear regression equation A=0.5781+0.0254 C (mg l(-1)), with a correlation coefficient of 0.9993. The detection limit is 0.12 mg l(-1), R.S.D. is 0.64% (40 mg l(-1), n=11), and average recovery is over 99.7%. This paper further improves the determination of DPH compared to the previous methods. The kinetic property and reaction mechanism have also been discussed. This proposed method has been successfully applied to the determination of DPH in injection and biological samples with satisfactory results. Topics: Benzalkonium Compounds; Chromogenic Compounds; Dopamine; Hydrogen-Ion Concentration; Indicators and Reagents; Naphthoquinones; Spectrophotometry | 2007 |