naphthoquinones and squaric-acid

naphthoquinones has been researched along with squaric-acid* in 2 studies

Other Studies

2 other study(ies) available for naphthoquinones and squaric-acid

ArticleYear
Squaric acid ester-based total synthesis of echinochrome A.
    The Journal of organic chemistry, 2002, Mar-08, Volume: 67, Issue:5

    The total synthesis of echinochrome A is described. Both key intermediates 5 and 8 were efficiently prepared from diisopropyl squarate 7. Nucleophilic addition of aryllithium 8 to 5, followed by thermal ring-expansion/cyclization of the 1,2-adduct 4, furnished hydroquinone 3. Oxidation and full deprotection of 3 gave the title compound.

    Topics: Animals; Catalysis; Chromatography, Thin Layer; Cyclization; Cyclobutanes; Esters; Molecular Structure; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular; Sea Urchins

2002
Comparative study on cytogenetic effects by diplatinum complexes of the ligands of naphthazarine and squaric acid in human lymphocytes.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    The effect of diplatinum complexes of the binucleating ligands of naphthazarine and squaric acid on Sister Chromatid Exchange (SCE) rates and human lymphocyte proliferation kinetics was studied. Squarodicisplatinum complex I, naphthazarindicisplatinum and squarodicisplatinum complex II induce cytotoxic effects as can be deduced from the resulted induction of SCEs and the produced cell division delays. Squarodicisplatinum complex I was found to be on a molar basis the most effective in causing markedly increased SCE rates and cell division delays. Cis-diaminodichloride platinum was found to be next in order of effectiveness with naphthazarindicisplatinum and squarodicisplatinum complex II following. Naphthazarine and SQA were found to be ineffective on induction of SCEs.

    Topics: Adolescent; Adult; Antineoplastic Agents; Cell Division; Cisplatin; Cyclobutanes; Humans; In Vitro Techniques; Lymphocytes; Male; Naphthoquinones; Organoplatinum Compounds; Sister Chromatid Exchange

1989