naphthoquinones and hydrazine

naphthoquinones has been researched along with hydrazine* in 2 studies

Other Studies

2 other study(ies) available for naphthoquinones and hydrazine

Article	Year
Taurine protects against the cytotoxicity of hydrazine, 1,4-naphthoquinone and carbon tetrachloride in isolated rat hepatocytes. Biochemical pharmacology, 1993, Aug-17, Volume: 46, Issue:4 Exposure of rat hepatocytes to hydrazine, carbon tetrachloride or 1,4-naphthoquinone results in cytotoxicity determined as uptake of Trypan blue and leakage of lactate dehydrogenase (LDH). After exposure of hepatocytes to hydrazine and 1,4-naphthoquinone, ATP was also measured and was found to be depleted. Addition of the beta-amino acid taurine to the hepatocyte incubation buffer partially protects the cells against the cytotoxicity of these three different cytotoxic compounds, as indicated by Trypan blue uptake and LDH leakage. Taurine also reduces the depletion of ATP caused by 1,4-naphthoquinone but not hydrazine. It is suggested that taurine may have a cytoprotective effect in vitro and may be a useful tool for the investigation of mechanisms of cytotoxicity. Topics: Animals; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Hydrazines; L-Lactate Dehydrogenase; Liver; Male; Naphthoquinones; Rats; Rats, Sprague-Dawley; Taurine; Trypan Blue	1993
VOLATILE AMINE OXIDASE INHIBITOR FROM HYDRAZINE DERIVATIVES. Biochemical pharmacology, 1964, Volume: 13 Topics: Air; Aminohydrolases; Azides; Copper; Cyanides; Hydrazines; Iproniazid; Liver; Manometry; Mitochondria; Monoamine Oxidase Inhibitors; Naphthoquinones; Nitrogen; Oxidoreductases; Oxygen; Phenylhydrazines; Research; Sarcina; Spectrophotometry; Thiourea; Tyramine	1964

Article

Year

Taurine protects against the cytotoxicity of hydrazine, 1,4-naphthoquinone and carbon tetrachloride in isolated rat hepatocytes.

Biochemical pharmacology, 1993, Aug-17, Volume: 46, Issue:4

Exposure of rat hepatocytes to hydrazine, carbon tetrachloride or 1,4-naphthoquinone results in cytotoxicity determined as uptake of Trypan blue and leakage of lactate dehydrogenase (LDH). After exposure of hepatocytes to hydrazine and 1,4-naphthoquinone, ATP was also measured and was found to be depleted. Addition of the beta-amino acid taurine to the hepatocyte incubation buffer partially protects the cells against the cytotoxicity of these three different cytotoxic compounds, as indicated by Trypan blue uptake and LDH leakage. Taurine also reduces the depletion of ATP caused by 1,4-naphthoquinone but not hydrazine. It is suggested that taurine may have a cytoprotective effect in vitro and may be a useful tool for the investigation of mechanisms of cytotoxicity.

Topics: Animals; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Hydrazines; L-Lactate Dehydrogenase; Liver; Male; Naphthoquinones; Rats; Rats, Sprague-Dawley; Taurine; Trypan Blue

1993

VOLATILE AMINE OXIDASE INHIBITOR FROM HYDRAZINE DERIVATIVES.

Biochemical pharmacology, 1964, Volume: 13

Topics: Air; Aminohydrolases; Azides; Copper; Cyanides; Hydrazines; Iproniazid; Liver; Manometry; Mitochondria; Monoamine Oxidase Inhibitors; Naphthoquinones; Nitrogen; Oxidoreductases; Oxygen; Phenylhydrazines; Research; Sarcina; Spectrophotometry; Thiourea; Tyramine

1964