naphthoquinones has been researched along with ferric-chloride* in 2 studies
2 other study(ies) available for naphthoquinones and ferric-chloride
| Article | Year |
|---|---|
Iron(III) Chloride Catalyzed Formation of 3,4-Dihydro-2H-pyrans from α-Alkylated 1,3-Dicarbonyls. Selective Synthesis of α- and β-Lapachone.
A mild, catalytic method for the synthesis of 3,4-dihydro-2H-pyrans is described. The FeCl3-catalyzed transformation of aryl- and alkyl β-diketones enables synthetic access to functionalized pyran core structures incorporated in many natural products and biologically active target structures. The method represents a mild alternative to currently available reaction protocols relying on stoichiometric reagents and harsh reaction conditions. This FeCl3-catalyzed transformation has enabled the selective synthesis of α-lapachone in two synthetic transformations and subsequently β-lapachone in three synthetic transformations, which is currently undergoing clinical trials as a potent anticancer agent. Topics: Catalysis; Chlorides; Combinatorial Chemistry Techniques; Ferric Compounds; Humans; Ketones; Molecular Structure; Naphthoquinones; Pyrans | 2016 |
Efficient generation of ortho-naphthoquinone methides from 1,4-epoxy-1,4-dihydronaphthalenes and their annulation with allyl silanes.
Topics: Catalysis; Chlorides; Cycloaddition Reaction; Ferric Compounds; Naphthalenes; Naphthoquinones; Silanes; Stereoisomerism | 2013 |