naphthoquinones has been researched along with ethyl-acetate* in 2 studies
2 other study(ies) available for naphthoquinones and ethyl-acetate
| Article | Year |
|---|---|
Three new naphthoquinones from the tubers of
Three new naphthoquinones, 5,6,7-trimethoxydunnione ( Topics: Antioxidants; Ethanol; Hexanes; Lamiales; Naphthoquinones; Plant Extracts | 2023 |
Cytotoxic Naphthoquinone and Azaanthraquinone Derivatives from an Endophytic Fusarium solani.
Bioactivity-guided fractionation of the ethyl acetate extract obtained from the culture of the endophytic fungus Fusarium solani resulted in the isolation of one new naphthoquinone, 9-desmethylherbarine (1), and two azaanthraquinone derivatives, 7-desmethylscorpinone (2) and 7-desmethyl-6-methylbostrycoidin (3), along with four known compounds. Their structures were elucidated by spectral analysis, as well as a direct comparison of spectral data with those of known compounds. Azaanthraquinones 2 and 3 showed cytotoxic activity against four human tumor cell lines, MDA MB 231, MIA PaCa2, HeLa, and NCI H1975. A molecular docking study suggested DNA interactions as the mode of action of these naphthoquinones and azaanthraquinones. Topics: Acetates; Anthraquinones; Antineoplastic Agents; Aza Compounds; Drug Screening Assays, Antitumor; Fusarium; HeLa Cells; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Nuclear Magnetic Resonance, Biomolecular | 2017 |