naphthoquinones and diphosphoric-acid

naphthoquinones has been researched along with diphosphoric-acid* in 1 studies

Other Studies

1 other study(ies) available for naphthoquinones and diphosphoric-acid

Article	Year
β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner. Proceedings of the National Academy of Sciences of the United States of America, 2023, 08-22, Volume: 120, Issue:34 Inositol pyrophosphates (PP-InsPs) are energetic signaling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration, PP-InsPs are tightly connected to cellular energy homeostasis. Consequently, an increasing number of studies involve PP-InsPs in metabolic disorders, such as type 2 diabetes, aspects of tumorigenesis, and hyperphosphatemia. Research conducted in yeast suggests that the PP-InsP pathway is activated in response to reactive oxygen species (ROS). However, the precise modulation of PP-InsPs during cellular ROS signaling is unknown. Here, we report how mammalian PP-InsP levels are changing during exposure to exogenous (H Topics: Adenosine Triphosphate; Cell Line, Tumor; Diabetes Mellitus, Type 2; Diphosphates; Humans; Hydrogen Peroxide; Inositol; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Oxygen; Reactive Oxygen Species	2023

Article

Year

β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner.

Proceedings of the National Academy of Sciences of the United States of America, 2023, 08-22, Volume: 120, Issue:34

Inositol pyrophosphates (PP-InsPs) are energetic signaling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration, PP-InsPs are tightly connected to cellular energy homeostasis. Consequently, an increasing number of studies involve PP-InsPs in metabolic disorders, such as type 2 diabetes, aspects of tumorigenesis, and hyperphosphatemia. Research conducted in yeast suggests that the PP-InsP pathway is activated in response to reactive oxygen species (ROS). However, the precise modulation of PP-InsPs during cellular ROS signaling is unknown. Here, we report how mammalian PP-InsP levels are changing during exposure to exogenous (H

Topics: Adenosine Triphosphate; Cell Line, Tumor; Diabetes Mellitus, Type 2; Diphosphates; Humans; Hydrogen Peroxide; Inositol; NAD(P)H Dehydrogenase (Quinone); Naphthoquinones; Oxygen; Reactive Oxygen Species

2023