naphthoquinones has been researched along with cyclopentenone* in 2 studies
2 other study(ies) available for naphthoquinones and cyclopentenone
| Article | Year |
|---|---|
Naphtoquinones and Sesquiterpene Cyclopentenones from the Sponge Smenospongia cerebriformis with Their Cytotoxic Activity.
Topics: Animals; Cell Line, Tumor; Circular Dichroism; Cyclopentanes; Humans; Magnetic Resonance Spectroscopy; Naphthoquinones; Porifera | 2017 |
Chemical constituents from Aphanamixis grandifolia.
(23E)-25-Methylcycloart-23-en-3β-ol (1), a cycloartane-type triterpenoid featuring an unusual skeleton of 31 carbon atoms, (17E)-cycloart-17,26-dien-3β-ol (2), a new cycloartane-type triterpenoid, and the other two new compounds 4R-hydroxy-4-(9S-hydroxy-12-methylhexan-6-yl)-3-methylcyclopent-2-enone (6) and 7-hydroxy-5-(2'-hydroxy-4',5'-dimethoxyphenyl)-2-methoxy-6-methyl-1,4-naphthoquinone (7), together with three known cycloart-3β-ol triterpenoids (3-5) were isolated from aerial parts of Aphanamixis grandifolia. Their structures were elucidated by spectroscopic analysis, and that of 1 was confirmed by single-crystal X-ray diffraction. The absolute configuration of two carbon stereocenters of compound 6 was determined to be 4R,9S by means of circular dichroism (CD) and auxiliary chiral α-methoxy-α-(trifluoromethyl)phenylacetic acid (MTPA) derivatives, respectively. The compound 3 exhibited significant cytotoxicities against HL-60, Hep G2 and HeLa, and compounds 1, 2, 5, 6 and 7 exhibited modest cytotoxicities. No activity of compound 4 could be due to the absence of the hydroxyl group at C-24. Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Circular Dichroism; Crystallography, X-Ray; Cyclopentanes; Humans; Magnetic Resonance Spectroscopy; Meliaceae; Models, Molecular; Naphthoquinones; Neoplasms; Triterpenes | 2010 |