naphthoquinones has been researched along with cyclohexadienone* in 1 studies
1 other study(ies) available for naphthoquinones and cyclohexadienone
Article | Year |
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Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against
Quinones and quinols are secondary metabolites of higher plants that are associated with many biological activities. The oxidative dearomatization of phenols induced by hypervalent iodine(III) reagents has proven to be a very useful synthetic approach for the preparation of these compounds, which are also widely used in organic synthesis and medicinal chemistry. Starting from several substituted phenols and naphthols, a series of cyclohexadienone and naphthoquinone derivatives were synthesized using different hypervalent iodine(III) reagents and evaluated for their in vitro antiprotozoal activity. Antiprotozoal activity was assessed against Topics: Antiprotozoal Agents; Cyclohexenes; Humans; Hydroquinones; Indicators and Reagents; Iodine; Malaria, Falciparum; Naphthols; Naphthoquinones; Oxidative Stress; Parasitic Sensitivity Tests; Phenols; Plasmodium falciparum; Trypanosoma brucei rhodesiense | 2022 |