naphazoline and oxymetazoline

naphazoline has been researched along with oxymetazoline in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199020 (68.97)18.7374
1990's3 (10.34)18.2507
2000's4 (13.79)29.6817
2010's1 (3.45)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
de Jong, AP; van Dam, H1
Andrews, PR; Craik, DJ; Martin, JL1
Batink, H; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Timmermans, PB; van Zwieten, PA1
Berman, J; Bigham, EC; Bishop, MJ; Garrison, DT; Gobel, MJ; Hodson, SJ; Irving, PE; Liacos, JA; Minick, DJ; Navas, F; Saussy, DL; Speake, JD1
Bigham, EC; Bishop, MJ; Drewry, DH; Garrison, DT; Gobel, MJ; Hodson, SJ; Irving, PE; Liacos, JH; Navas, F; Saussy, DL; Speake, JD1
Agbaba, D; Filipic, S; Nikolic, K1
Kobinger, W; Pichler, L2
Cherry, JD; Dudley, JP1
Rolls, ET; Shaw, SG1
Endoh, M; Schümann, HJ1
Ruffolo, RR1
Chandranath, SI; Gokhale, SD; Sharif, SI1
Díaz-Toledo, A; Martí, MC1
Schmitt, H; Tsoucaris-Kupfer, D1
Reinhardt, D; Wagner, J1
Endo, M; Schümann, HJ; Wagner, J1
Furkert, K1
Starke, K1
Le Douarec, JC; Petillot, N; Schmitt, H1
Fénard, S; Schmitt, H1
Jones, DJ; McKenna, LF1
Large, WA1
Mauracher, E; Rybiczka, R1
Hofmann, T; Koidl, B; Wolf, G1
Mickenhagen, A; Neugebauer, P; Siefer, O; Stennert, E1
Chaumais, MC; Girerd, B; Guignabert, C; Günther, S; Humbert, M; Montani, D; O'Connell, C; Perrin, S; Savale, L; Simonneau, G; Sitbon, O1
Chen, YW; Chiu, CC; Chou, AK; Hung, CH; Wang, JJ; Zhu, GC1

Reviews

3 review(s) available for naphazoline and oxymetazoline

ArticleYear
alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:12

    Topics: Adipose Tissue; Animals; Blood Platelets; Central Nervous System; Humans; Islets of Langerhans; Melanocytes; Muscle, Smooth, Vascular; Nerve Endings; Norepinephrine; Parasympathetic Nervous System; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Serotonin; Synapses

1982
Fundamentals of receptor theory: basics for shock research.
    Circulatory shock, 1992, Volume: 37, Issue:2

    Topics: Binding, Competitive; Drug Design; Naphazoline; Oxymetazoline; Phentolamine; Phenylephrine; Receptors, Adrenergic; Research Design; Shock, Septic; Signal Transduction; Therapeutic Equivalency

1992
[Rhinologic agents. 14].
    Pharmazeutische Praxis, 1967, Volume: 9

    Topics: Acridines; Adrenal Cortex Hormones; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Boric Acids; Chloramphenicol; Dexamethasone; Diphenhydramine; Ephedrine; Epinephrine; Histamine H1 Antagonists; Humans; Hydrocortisone; Imidazoles; Methoxamine; Naphazoline; Nasal Decongestants; Neomycin; Nose Diseases; Oils, Volatile; Oxymetazoline; Pheniramine; Prednisolone; Prednisone; Triamcinolone; Tripelennamine

1967

Trials

1 trial(s) available for naphazoline and oxymetazoline

ArticleYear
Oxymetazoline ophthalmic solution versus naphazoline solution in non-infectious conjunctivitis.
    Pharmatherapeutica, 1983, Volume: 3, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Conjunctivitis; Double-Blind Method; Female; Humans; Imidazoles; Male; Middle Aged; Naphazoline; Ophthalmic Solutions; Oxymetazoline

1983

Other Studies

25 other study(ies) available for naphazoline and oxymetazoline

ArticleYear
Ultraviolet photoelectron spectroscopy of cyclic amidines. 1. Electronic structure of some alpha-adrenergic benzylimidazolines.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:11

    Topics: Adrenergic alpha-Agonists; Chemical Phenomena; Chemistry; Imidazoles; Naphazoline; Oxymetazoline; Quantum Theory; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1979
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cell Membrane; Clonidine; Kinetics; Prazosin; Quinazolines; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship; Vasoconstriction

1984
2-(Anilinomethyl)imidazolines as alpha(1)-adrenoceptor agonists: the identification of alpha(1A) subtype selective 2'-carboxylic acid esters and amides.
    Bioorganic & medicinal chemistry letters, 2001, Nov-05, Volume: 11, Issue:21

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Amides; Carboxylic Acids; Esters; Imidazoles; Structure-Activity Relationship

2001
2-(anilinomethyl)imidazolines as alpha1A adrenergic receptor agonists: 2'-heteroaryl and 2'-oxime ether series.
    Bioorganic & medicinal chemistry letters, 2002, Feb-25, Volume: 12, Issue:4

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Calcium Signaling; Cell Line; Cloning, Molecular; Heterocyclic Compounds; Humans; Imidazoles; Oximes; Phenylephrine; Protein Binding; Rats; Receptors, Adrenergic, alpha-1

2002
QSAR study of imidazoline antihypertensive drugs.
    Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15

    Topics: Antihypertensive Agents; Binding Sites; Imidazoline Receptors; Imidazolines; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship

2008
Investigation into some imidazoline compounds, with respect to peripheral alpha-adrenoceptor stimulation and depression of cardiovascular centers.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 291, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Atropine; Blood Pressure; Brain; Cats; Clonidine; Dogs; Female; Heart Rate; Imidazoles; Imidazolidines; Male; Naphazoline; Oxymetazoline; Pressoreceptors; Rats; Receptors, Adrenergic; Reflex; Vagotomy; Vagus Nerve; Vasomotor System; Xylazine

1975
Effects of topical nasal decongestants on the cilia of a chicken embryo tracheal organ culture system.
    The Laryngoscope, 1978, Volume: 88, Issue:1 Pt 1

    Topics: Animals; Chick Embryo; Cilia; In Vitro Techniques; Naphazoline; Nasal Decongestants; Oxymetazoline; Phenylephrine; Trachea

1978
Is the release of noradrenaline necessary for self-stimulation of the brain?
    Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:4

    Topics: Amphetamine; Animals; Benserazide; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Clonidine; Disulfiram; Levodopa; Male; Naphazoline; Nerve Endings; Norepinephrine; Oxymetazoline; Phenylephrine; Rats; Receptors, Drug; Reserpine; Self Stimulation

1976
Frequency-dependence of the positive inotropic effect of methoxamine and naphazoline mediated by alpha-Adrenoceptors in the isolated rabbit papillary muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; In Vitro Techniques; Methoxamine; Myocardial Contraction; Naphazoline; Oxymetazoline; Papaverine; Papillary Muscles; Phentolamine; Rabbits; Receptors, Adrenergic; Stimulation, Chemical

1975
Proceedings: Central nervous cardiovascular depression, a potential action of alpha-adrenoceptors stimulating imidazoline derivatives.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287 Suppl

    Topics: Animals; Cardiovascular System; Cats; Clonidine; Dogs; Imidazoles; Medulla Oblongata; Naphazoline; Oxymetazoline

1975
Pharmacological characterization of the postjunctional alpha-adrenoceptors of the rat isolated seminal vesicle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Naphazoline; Norepinephrine; Oxymetazoline; Phenoxybenzamine; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Seminal Vesicles; Yohimbine

1990
Relationship between alpha-adrenoceptor occupancy and contractile response in rat vas deferens. Experimental and theoretical analysis.
    European journal of pharmacology, 1988, Nov-08, Volume: 156, Issue:3

    Topics: Animals; Dibenzylchlorethamine; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Male; Models, Biological; Muscle Contraction; Naphazoline; Norepinephrine; Oxymetazoline; Rats; Receptors, Adrenergic, alpha; Vas Deferens

1988
Hypothermic effect of alpha-sympathomimetic agents and their antagonism by adrenergic and cholinergic blocking drugs.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aniline Compounds; Animals; Body Temperature; Cerebral Ventricles; Clonidine; Dose-Response Relationship, Drug; Hypothalamus; Injections; Injections, Intraperitoneal; Naphazoline; Oxazoles; Oxymetazoline; Parasympatholytics; Rats; Stereotaxic Techniques; Sympatholytics; Thiazines; Time Factors; Toluidines; Xylenes

1972
Characterization of the adrenoceptors mediating the positive ino- and chronotropic effect of phenylephrine on isolated atria from guinea pigs and rabbits by means of adrenolytic drugs.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methoxamine; Naphazoline; Oxymetazoline; Perfusion; Phentolamine; Phenylephrine; Pindolol; Rabbits; Receptors, Adrenergic; Reserpine; Stimulation, Chemical

1974
Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by alpha- and beta-adrenoceptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 284, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Depression, Chemical; Epinephrine; Heart; In Vitro Techniques; Isoproterenol; Methoxamine; Muscles; Naphazoline; Norepinephrine; Oxymetazoline; Papaverine; Papillary Muscles; Phentolamine; Phenylephrine; Phosphodiesterase Inhibitors; Pindolol; Rabbits; Receptors, Adrenergic; Reserpine; Stimulation, Chemical; Theophylline

1974
Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart.
    Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 274, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Cocaine; Drug Interactions; Electric Stimulation; Ergotamine; Female; Heart; Male; Naphazoline; Nerve Endings; Norepinephrine; Oxymetazoline; Parasympathetic Nervous System; Perfusion; Phenylephrine; Rabbits; Receptors, Drug; Sympathomimetics; Synaptic Transmission

1972
Antinociceptive effects of some alpha-sympathomimetic agents.
    Neuropharmacology, 1974, Volume: 13, Issue:5

    Topics: Analgesics; Aniline Compounds; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Imidazoles; Injections, Intraperitoneal; Naphazoline; Naphthalenes; Oxazoles; Oxymetazoline; Rats; Reaction Time; Reflex, Startle; Sympathomimetics; Tetrazoles; Thiazines; Toluidines; Vocalization, Animal

1974
[Effect of sympathomimetics on the vasomotor centers].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 190, Issue:2

    Topics: Animals; Blood Pressure; Bradycardia; Cats; Hemodynamics; Hypertension; Hypotension; Isoproterenol; Naphazoline; Norepinephrine; Oxymetazoline; Phenylephrine; Splanchnic Nerves; Sympathomimetics; Vasomotor System

1971
Alpha adrenergic receptor mediated formation of cyclic AMP in rat spinal cord.
    Journal of cyclic nucleotide research, 1980, Volume: 6, Issue:2

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Cyclic AMP; Male; Methoxamine; Naphazoline; Oxymetazoline; Phenylephrine; Rats; Spinal Cord

1980
Membrane potential responses to ionophoretically applied alpha-adrenoceptor agonists in the mouse anococcygeus muscle.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; In Vitro Techniques; Iontophoresis; Kinetics; Membrane Potentials; Mice; Muscles; Naphazoline; Norepinephrine; Oxymetazoline; Temperature

1983
[In vitro studies of the effect of vasoconstrictor nose drops on ciliary epithelium of human nasal mucosa].
    Laryngo- rhino- otologie, 1995, Volume: 74, Issue:9

    Topics: Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Mucociliary Clearance; Naphazoline; Nasal Decongestants; Nasal Mucosa; Oxymetazoline; Phenylephrine

1995
[The influence of different alpha-sympathomimetic drugs and benzalkoniumchlorid on the ciliary beat frequency of in vitro cultured human nasal mucosa cells].
    Laryngo- rhino- otologie, 2008, Volume: 87, Issue:1

    Topics: Adrenergic alpha-Agonists; Anti-Infective Agents, Local; Benzalkonium Compounds; Cilia; Dose-Response Relationship, Drug; Equipment Design; Fourier Analysis; Humans; Imidazoles; In Vitro Techniques; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Mucociliary Clearance; Naphazoline; Nasal Mucosa; Oxymetazoline; Signal Processing, Computer-Assisted; Software; Video Recording

2008
Nasal decongestant exposure in patients with pulmonary arterial hypertension: a pilot study.
    The European respiratory journal, 2015, Volume: 46, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amines; Amphetamines; Case-Control Studies; Female; Humans; Hypertension, Pulmonary; Inflammation; Male; Middle Aged; Naphazoline; Nasal Decongestants; Oxymetazoline; Phenylpropanolamine; Pilot Projects; Pseudoephedrine; Young Adult

2015
Naphazoline and oxymetazoline are superior to epinephrine in enhancing the cutaneous analgesia of lidocaine in rats.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:2

    Topics: Adrenergic Agonists; Analgesia; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Epinephrine; Lidocaine; Naphazoline; Oxymetazoline; Pain; Rats; Rats, Sprague-Dawley

2023