naphazoline and nafimidone

naphazoline has been researched along with nafimidone in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Boddy, AV; Kerr, BM; Levy, RH; Moreland, TA1
Alexander, OF; Dow, RJ; Graham, DJ; Hall, DJ; Kurz, L; Rush, WR; Tokes, L1
Caccia, S; Conti, I; Fracasso, C; Salmona, M; Testa, R1
Caliş, U; Dalkara, S; Ertan, M; Sunal, R1
Gunawan, S; Treiman, DM2
Durham, DG; Reid, R; Shivji, AS; Taylor, RB1
Beedle, EE; Krushinski, JH; Leander, JD; Rathbun, RC; Robertson, DW; Wong, DT1
Eadie, J; Graham, DJ; Leadbetter, BM; Metcalf, R1
Javitt, NB; Lee, C; Martin, KO1
Dalkara, S; Karakurt, A; Kendi, E; Ozalp, M; Ozbey, S; Stables, JP1
Alagöz, MA; Calış, U; Dalkara, S; Karakurt, A; Sayoğlu, B1
Acar, MF; Dalkara, S; Sari, S1
Avci, A; Barut, B; Koçak Aslan, E; Marcinkowska, M; Özel, A; Sabuncuoğlu, S; Sari, S; Siwek, A1

Other Studies

14 other study(ies) available for naphazoline and nafimidone

ArticleYear
Pharmacokinetic consequences of product stereoselectivity in the metabolism of nafimidone: estimation of fraction metabolized.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:8

    Topics: Animals; Biotransformation; Haplorhini; Naphazoline; Stereoisomerism

1991
The metabolism of nafimidone hydrochloride in the dog, primates and man.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:1

    Topics: Adult; Animals; Anticonvulsants; Dogs; Haplorhini; Humans; Imidazoles; Male; Mass Spectrometry; Middle Aged; Naphazoline

1990
Interaction of the anticonvulsants, denzimol and nafimidone, with liver cytochrome P450 in the rat.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:1

    Topics: Animals; Anticonvulsants; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme System; Diazepam; Imidazoles; In Vitro Techniques; Liver; Male; Microsomes, Liver; Naphazoline; Rats; Rats, Inbred Strains; Sleep; Time Factors

1988
The significance of the imidazole ring in anticonvulsant activity of (arylalkyl)imidazoles.
    Archiv der Pharmazie, 1988, Volume: 321, Issue:12

    Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Imidazoles; Male; Mice; Naphazoline

1988
High-performance liquid chromatographic determination of nafimidone and its major metabolite nafimidone alcohol in human plasma and urine.
    Journal of chromatography, 1987, Mar-06, Volume: 414, Issue:2

    Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Humans; Imidazoles; Kinetics; Naphazoline

1987
Pharmacokinetics of nafimidone in patients with chronic intractable epilepsy.
    Clinical pharmacokinetics, 1987, Volume: 12, Issue:6

    Topics: Adult; Anticonvulsants; Chronic Disease; Epilepsy; Female; Half-Life; Humans; Imidazoles; Kinetics; Male; Middle Aged; Naphazoline

1987
Development of a stability-indicating assay for nafimidone [1-(2-naphthoylmethyl)imidazole hydrochloride] by high-performance liquid chromatography.
    Journal of chromatography, 1986, Feb-26, Volume: 353

    Topics: Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Imidazoles; Naphazoline; Temperature

1986
Structure-activity relationships of (arylalkyl)imidazole anticonvulsants: comparison of the (fluorenylalkyl)imidazoles with nafimidone and denzimol.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Anticonvulsants; Cerebral Cortex; Chemical Phenomena; Chemistry; Drug Synergism; Female; Flunitrazepam; Hexobarbital; Imidazoles; Mice; Naphazoline; Rats; Rats, Inbred F344; Seizures; Sleep; Structure-Activity Relationship

1986
Simultaneous determination of nafimidone [1-(2-naphthoylmethyl)imidazole], a new anticonvulsant agent, and a major metabolite in plasma by high-performance liquid chromatography.
    Journal of chromatography, 1983, Jun-10, Volume: 275, Issue:1

    Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Dogs; Haplorhini; Humans; Imidazoles; Male; Naphazoline; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1983
Bile acid synthesis: 7 alpha-hydroxylation of intermediates in the sterol 27-hydroxylase metabolic pathway.
    Journal of lipid research, 1996, Volume: 37, Issue:6

    Topics: Animals; Bile Acids and Salts; Cell Fractionation; Cholestanetriol 26-Monooxygenase; Cholesterol; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Hydroxycholesterols; Kinetics; Male; Mesocricetus; Microsomes, Liver; Naphazoline; Steroid Hydroxylases; Substrate Specificity

1996
Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities.
    European journal of medicinal chemistry, 2001, Volume: 36, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Bacteria; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Electroshock; Ethers; Fungi; Humans; Isomerism; Mice; Microbial Sensitivity Tests; Molecular Conformation; Naphazoline; Oximes; Pentylenetetrazole; Rats; Reflex; Seizures; Structure-Activity Relationship

2001
Synthesis of some novel 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime ester derivatives and evaluation of their anticonvulsant activity.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Animals; Anticonvulsants; Electroshock; Esters; Imidazoles; Isomerism; Mice; Motor Activity; Naphazoline; Neuropsychological Tests; Oximes; Seizures; Structure-Activity Relationship

2012
Synthesis, in vivo anticonvulsant testing, and molecular modeling studies of new nafimidone derivatives.
    Drug development research, 2019, Volume: 80, Issue:5

    Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Imidazoles; Injections, Intraperitoneal; Male; Mice; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Naphazoline; Rats; Receptors, GABA-A; Seizures; Structure-Activity Relationship

2019
Potential of nafimidone derivatives against co-morbidities of epilepsy: In vitro, in vivo, and in silico investigations.
    Drug development research, 2022, Volume: 83, Issue:1

    Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Epilepsy; Mice; Molecular Docking Simulation; Morbidity; Naphazoline

2022