naltrexone has been researched along with spiradoline in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (44.00) | 18.2507 |
| 2000's | 8 (32.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, GI; Breder, CD; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yasuda, K | 1 |
| Kamei, J; Kasuya, Y; Tanihara, H | 2 |
| Holtzman, SG; Jones, DN | 1 |
| Archer, S; Glick, SD; Maisonneuve, IM; Raucci, J | 1 |
| Dykstra, LA; Pitts, RC | 1 |
| Hubbard, JI | 1 |
| Ingenito, AJ; Zhai, QZ | 1 |
| Maslov, LN; Naryzhnaya, NV; Tam, SW | 1 |
| Holtzman, SG; Powell, KR | 1 |
| Butelman, ER; Harris, TJ; Kreek, MJ | 1 |
| Sutherland, J; Walker, EA; Young, AM; Zhang, L | 1 |
| Holtzman, SG | 1 |
| Moore, TT; Potter, DE | 1 |
| Greene, JL; McClean, JM; Smith, MA | 1 |
| Platt, DM; Rowlett, JK; Rüedi-Bettschen, D; Spealman, RD; Valdez, GR | 1 |
| Baker, AJ; Bambino, T; Karliner, JS; Lovett, DH; McCloskey, DT; Nguyen, AP; Nissenson, RA; Turcato, S; Turnbull, L; Wang, GY; Zhu, BQ | 1 |
| Ballard, ME; Harmon, AC; Holtzman, SG; White, DA | 1 |
| Braida, D; Capurro, V; Parolaro, D; Rubino, T; Sala, M; Viganò, D; Zani, A | 1 |
| Platt, DM; Rowlett, JK; Rüedi-Bettschen, D; Spealman, RD | 1 |
| Climent, L; Horga, A; Horga, JF; Peiró, AM; Zapater, P | 1 |
| Dortch-Carnes, J; Russell-Randall, KR | 1 |
| Acevedo, MB; Nizhnikov, ME; Pautassi, RM; Spear, NE | 1 |
| Bordner, KA; Carter, JM; Landin, JD; Nizhnikov, ME; Pautassi, RM; Spear, NE; Varlinskaya, EI; Werner, DF | 1 |
| Copp, SW; Kaufman, MP; Stone, AJ; Yamauchi, K | 1 |
25 other study(ies) available for naltrexone and spiradoline
| Article | Year |
|---|---|
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Somatostatin; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution | 1993 |
Modulation of kappa-mediated antitussive activity in rats by a delta-agonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antitussive Agents; Cough; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Male; Morphinans; Naltrexone; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Reflex | 1992 |
Long term kappa-opioid receptor blockade following nor-binaltorphimine.
Topics: Analgesics; Animals; Male; Naltrexone; Pain Measurement; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa | 1992 |
Antitussive effects of two specific kappa-opioid agonists, U-50,488H and U-62,066E, in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antitussive Agents; Cisterna Magna; Cough; Injections; Ketanserin; Male; Methysergide; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Rats, Inbred Strains; Reflex | 1990 |
Kappa opioid inhibition of morphine and cocaine self-administration in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cocaine; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Morphine; Naltrexone; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration | 1995 |
Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.
Topics: Analgesics; Animals; Azocines; Benzeneacetamides; Benzofurans; Dose-Response Relationship, Drug; Male; Morphine; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Saimiri | 1994 |
Water transport in cultured cells from the rat inner medullary collecting duct.
Topics: Animals; Arginine Vasopressin; Biological Transport; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Kidney Medulla; Kidney Tubules, Collecting; Naltrexone; Narcotic Antagonists; Osmosis; Oxytocin; Pyrrolidines; Rats; Receptors, Opioid, kappa; Water | 1996 |
Comparative hypotensive actions of three nonpeptide kappa opioid agonists on hippocampus of SHRs and normotensive WKY rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Benzomorphans; Dose-Response Relationship, Drug; Hippocampus; Male; Naltrexone; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid, kappa | 1998 |
Ligands for opioid and sigma-receptors improve cardiac electrical stability in rat models of post-infarction cardiosclerosis and stress.
Topics: Animals; Anti-Arrhythmia Agents; beta-Endorphin; Disease Models, Animal; Dynorphins; Enkephalin, Leucine-2-Alanine; Heart; Immobilization; Ligands; Morphine; Myocardial Infarction; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Piperidines; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Stress, Physiological; Ventricular Fibrillation | 1999 |
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes | 1999 |
Effects of E-2078, a stable dynorphin A(1-8) analog, on sedation and serum prolactin levels in rhesus monkeys.
Topics: Animals; Azocines; Dose-Response Relationship, Drug; Dynorphins; Female; Hypnotics and Sedatives; Injections, Subcutaneous; Macaca mulatta; Male; Motor Activity; Muscle Relaxation; Naltrexone; Narcotic Antagonists; Peptide Fragments; Prolactin; Pyrrolidines; Receptors, Opioid, kappa; Time Factors | 1999 |
Discriminative stimulus effects of two doses of fentanyl in rats: pharmacological selectivity and effect of training dose on agonist and antagonist effects of mu opioids.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Fentanyl; Male; Methadone; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Further characterization of the discriminative stimulus effects of spiradoline.
Topics: Analgesics, Non-Narcotic; Animals; Benzeneacetamides; Discrimination Learning; Drug Interactions; Male; Morphine; Naltrexone; Narcotic Antagonists; Nicotinic Antagonists; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Tetrahydronaphthalenes | 2000 |
Kappa opioid agonist-induced changes in IOP: correlation with 3H-NE release and cAMP accumulation.
Topics: Analysis of Variance; Animals; Ciliary Body; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulation; Intraocular Pressure; Male; Naltrexone; Norepinephrine; Pupil; Pyrrolidines; Rabbits; Radioimmunoassay; Receptors, Opioid, kappa | 2001 |
Enhanced sensitivity to the antinociceptive effects of kappa opioids in naltrexone-treated rats: dose- and time-dependent effects.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pentazocine; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, Opioid, kappa | 2003 |
Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms.
Topics: Animals; Behavior, Addictive; Benzofurans; Clonidine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Male; Naltrexone; Norepinephrine; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri; Self Administration; Stress, Psychological | 2007 |
Expression of a Gi-coupled receptor in the heart causes impaired Ca2+ handling, myofilament injury, and dilated cardiomyopathy.
Topics: Actin Cytoskeleton; Animals; Calcium; Cardiomyopathy, Dilated; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Matrix Metalloproteinase 2; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, G-Protein-Coupled; Receptors, Opioid, kappa; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Time Factors; Ventricular Function, Left | 2008 |
Acute delta- and kappa-opioid agonist pretreatment potentiates opioid antagonist-induced suppression of water consumption.
Topics: Analgesics, Opioid; Animals; Benzamides; Benzomorphans; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Deprivation | 2008 |
Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia divinorum, in rodents.
Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Binding, Competitive; Brain; Cyclohexanols; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Emotions; Injections, Subcutaneous; Male; Mice; Models, Animal; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Salvia; Swimming | 2009 |
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys: kappa opioid and serotonergic mechanisms.
Topics: Animals; Benzofurans; Citalopram; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Fluoxetine; Ligands; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Saimiri; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin; Serotonin 5-HT1 Receptor Agonists | 2010 |
Ketanserin potentiates morphine-induced antinociception mediated by kappa-receptor activation.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Ketanserin; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Pain; Pain Measurement; Pain Threshold; Prazosin; Pyrrolidines; Receptors, Adrenergic, alpha-1; Receptors, Opioid, kappa; Receptors, Serotonin, 5-HT2; Serotonin Antagonists | 2011 |
Kappa opioid receptor localization and coupling to nitric oxide production in cells of the anterior chamber.
Topics: Analgesics; Animals; Cells, Cultured; Ciliary Body; Endothelium, Corneal; Enzyme Inhibitors; Estradiol; Humans; Intraocular Pressure; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrrolidines; Rabbits; Receptors, Opioid, kappa; Trabecular Meshwork | 2011 |
Early role of the κ opioid receptor in ethanol-induced reinforcement.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Depressants; Conditioning, Classical; Dose-Response Relationship, Drug; Ethanol; Female; Guanidines; Male; Morphinans; Motor Activity; Naltrexone; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement, Psychology | 2012 |
Brief prenatal ethanol exposure alters behavioral sensitivity to the kappa opioid receptor agonist (U62,066E) and antagonist (Nor-BNI) and reduces kappa opioid receptor expression.
Topics: Alcohol Drinking; Animals; Brain Chemistry; Conditioning, Psychological; Ethanol; Female; Gene Expression; Male; Naltrexone; Pregnancy; Prenatal Exposure Delayed Effects; Pyrrolidines; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 2014 |
Effects of peripheral and spinal κ-opioid receptor stimulation on the exercise pressor reflex in decerebrate rats.
Topics: Animals; Decerebrate State; Femoral Artery; Injections, Intra-Arterial; Injections, Spinal; Ligation; Male; Models, Animal; Naltrexone; Peripheral Nerves; Physical Conditioning, Animal; Pressoreceptors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Spinal Nerves | 2014 |