Compounds > naltrexone

naltrexone and salvinorin a

naltrexone has been researched along with salvinorin a in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (47.37)29.6817
2010's9 (47.37)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Azar, MR; Cashman, JR; Ghirmai, S1
Fantegrossi, WE; Koreeda, M; Kugle, KM; Valdes, LJ; Woods, JH1
McCurdy, CR; Nieto, MJ; Smith, GH; Sufka, KJ; Warnick, JE1
Erlichman, JS; French, LG; John, TF1
Butelman, ER; Kreek, MJ; Mandau, M; Prisinzano, TE; Tidgewell, K; Yuferov, V1
Braida, D; Gori, E; Guerini-Rocco, C; Limonta, V; Pegorini, S; Sala, M; Zani, A1
Braida, D; Capurro, V; Fadda, P; Fratta, W; Gori, E; Limonta, V; Mascia, P; Parolaro, D; Rubino, T; Sala, M; Zani, A1
Butelman, ER; Kreek, MJ; Prisinzano, TE; Rus, S; Simpson, DS; Wolf, A1
Braida, D; Capurro, V; Parolaro, D; Rubino, T; Sala, M; Viganò, D; Zani, A1
Chefer, VI; Shippenberg, TS; Tejeda, HA; Zapata, A1
Carlezon, WA; Chartoff, EH; Cohen, BM; Damez-Werno, D; Potter, DN1
Dicay, M; Fichna, J; Janecka, A; Lewellyn, K; MacNaughton, WK; Storr, MA; Zjawiony, JK1
Braida, D; Capurro, V; Donzelli, A; Martucci, R; Sala, M1
Do Rego, JC; Fichna, J; Grzywacz, D; Kamysz, W; Polepally, PR; Sałaga, M; Sibaev, A; Sobczak, M; Storr, M; Zjawiony, JK1
Addy, PH; Antonijoan, RM; Ballester, MR; Barker, S; Claramunt, J; Coimbra, J; Garrido, M; González, M; Griffiths, RR; Johnson, MW; Lomnicka, I; Maqueda, AE; Puntes, M; Riba, J; Valle, M; Waguespack, M1
Abel, T; Chen, C; Liang, X; Liu, R; Ma, J; Su, D; Xi, C1
Dong, HP; He, ZZ; Ma, XX; Wang, ZH; Zhou, W1
Colontonio, MM; Cornett, EM; Gennuso, SA; Kaye, AD; Kaye, AJ; Latimer, DR; Patil, SS; Urman, RD; Vadivelu, N1
Freeman, KB; Huskinson, SL; Naylor, JE; Prisinzano, TE; Townsend, EA; Zamarripa, CA1

Reviews

1 review(s) available for naltrexone and salvinorin a

ArticleYear
New opioid receptor modulators and agonists.
    Best practice & research. Clinical anaesthesiology, 2018, Volume: 32, Issue:2

    Topics: Analgesics, Opioid; Animals; Diterpenes, Clerodane; Humans; Indoles; Naltrexone; Receptors, Opioid; Spiro Compounds; Thiophenes

2018

Trials

1 trial(s) available for naltrexone and salvinorin a

ArticleYear
Naltrexone but Not Ketanserin Antagonizes the Subjective, Cardiovascular, and Neuroendocrine Effects of Salvinorin-A in Humans.
    The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:7

    Topics: Adult; Blood Pressure; Diterpenes, Clerodane; Double-Blind Method; Drug Interactions; Female; Hallucinogens; Healthy Volunteers; Humans; Hydrocortisone; Ketanserin; Male; Naltrexone; Narcotic Antagonists; Perception; Prolactin; Serotonin Antagonists; Young Adult

2016

Other Studies

17 other study(ies) available for naltrexone and salvinorin a

ArticleYear
Synthesis and pharmacological evaluation of 6-naltrexamine analogs for alcohol cessation.
    Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18

    Topics: Alcohol Deterrents; Alcoholism; Animals; Humans; Liver; Male; Mice; Naltrexone; Nociceptin Receptor; Protein Binding; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship

2009
Kappa-opioid receptor-mediated effects of the plant-derived hallucinogen, salvinorin A, on inverted screen performance in the mouse.
    Behavioural pharmacology, 2005, Volume: 16, Issue:8

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzeneacetamides; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Psychotropic Drugs; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil

2005
Antinociceptive profile of salvinorin A, a structurally unique kappa opioid receptor agonist.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Diterpenes; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Hot Temperature; Male; Mice; Muscle Contraction; Naltrexone; Nociceptors; Pain Measurement; Plant Leaves; Psychotropic Drugs; Reaction Time; Receptors, Opioid, kappa

2006
The antinociceptive effect of salvinorin A in mice.
    European journal of pharmacology, 2006, Sep-18, Volume: 545, Issue:2-3

    Topics: Analgesics; Animals; Diterpenes; Diterpenes, Clerodane; Injections, Spinal; Male; Mice; Naltrexone

2006
Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:1

    Topics: Amino Acid Sequence; Animals; Benzeneacetamides; Biomarkers; Cloning, Molecular; Diterpenes; Diterpenes, Clerodane; Female; Hallucinogens; Humans; Macaca mulatta; Male; Molecular Sequence Data; Naltrexone; Prolactin; Pyrrolidines; Receptors, Opioid, kappa; Sex Characteristics

2007
Hallucinatory and rewarding effect of salvinorin A in zebrafish: kappa-opioid and CB1-cannabinoid receptor involvement.
    Psychopharmacology, 2007, Volume: 190, Issue:4

    Topics: Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Psychological; Diterpenes; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Hallucinogens; Models, Animal; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Reinforcement, Psychology; Reproducibility of Results; Reward; Rimonabant; Swimming; Time Factors; Zebrafish

2007
Involvement of kappa-opioid and endocannabinoid system on Salvinorin A-induced reward.
    Biological psychiatry, 2008, Feb-01, Volume: 63, Issue:3

    Topics: Analysis of Variance; Animals; Antioxidants; Behavior, Animal; Cannabinoid Receptor Modulators; Conditioning, Operant; Diterpenes; Diterpenes, Clerodane; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Endocannabinoids; Male; Microdialysis; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reward; Rimonabant; Self Administration

2008
The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1

    Topics: Animals; Biomarkers; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Female; Furans; Loperamide; Macaca mulatta; Male; Naltrexone; Prolactin; Pyrones; Receptors, Opioid, mu

2008
Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia divinorum, in rodents.
    British journal of pharmacology, 2009, Volume: 157, Issue:5

    Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Binding, Competitive; Brain; Cyclohexanols; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Emotions; Injections, Subcutaneous; Male; Mice; Models, Animal; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Salvia; Swimming

2009
The effects of kappa-opioid receptor ligands on prepulse inhibition and CRF-induced prepulse inhibition deficits in the rat.
    Psychopharmacology, 2010, Volume: 210, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzeneacetamides; Corticotropin-Releasing Hormone; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Ligands; Male; Naltrexone; Neural Inhibition; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reflex, Startle

2010
Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity.
    Biological psychiatry, 2011, Oct-15, Volume: 70, Issue:8

    Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Diterpenes, Clerodane; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Male; Naltrexone; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Self Stimulation; Signal Transduction; Time Factors

2011
Salvinorin A has antiinflammatory and antinociceptive effects in experimental models of colitis in mice mediated by KOR and CB1 receptors.
    Inflammatory bowel diseases, 2012, Volume: 18, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Blotting, Western; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Diterpenes, Clerodane; Gastrointestinal Motility; Male; Mice; Naltrexone; Pain; Peroxidase; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid, kappa; Salvia; Trinitrobenzenesulfonic Acid

2012
Learning and memory impairment induced by salvinorin A, the principal ingredient of Salvia divinorum, in wistar rats.
    International journal of toxicology, 2011, Volume: 30, Issue:6

    Topics: Animals; Attention; Avoidance Learning; Diterpenes, Clerodane; Hallucinogens; Inhibition, Psychological; Learning; Male; Maze Learning; Memory, Long-Term; Motor Activity; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, kappa; Recognition, Psychology; Salvia

2011
Novel orally available salvinorin A analog PR-38 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 350, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Diarrhea; Disease Models, Animal; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Exploratory Behavior; Gastrointestinal Motility; Injections, Intraperitoneal; Irritable Bowel Syndrome; Male; Mice; Motor Activity; Naltrexone; Receptors, Opioid, kappa; Receptors, Opioid, mu

2014
The Role of κ Opioid Receptor in Brain Ischemia.
    Critical care medicine, 2016, Volume: 44, Issue:12

    Topics: Animals; Apoptosis; Blotting, Western; Brain Ischemia; Disease Models, Animal; Diterpenes, Clerodane; Male; Mice; Mice, Inbred C57BL; Naltrexone; Receptors, Opioid, kappa; Reperfusion Injury

2016
Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018, Mar-15, Volume: 51, Issue:5

    Topics: Animals; Brain Ischemia; Cerebral Arteries; Chromones; Cyclic GMP; Disease Models, Animal; Diterpenes, Clerodane; Male; Morpholines; Naltrexone; NG-Nitroarginine Methyl Ester; Phosphatidylinositol 3-Kinases; Pia Mater; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction

2018
Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys.
    Psychopharmacology, 2020, Volume: 237, Issue:5

    Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Cocaine; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Macaca mulatta; Male; Morphinans; Naltrexone; Narcotic Antagonists; Oxycodone; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration; Spiro Compounds

2020