naltrexone has been researched along with saccharin in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.16) | 18.7374 |
| 1990's | 8 (21.05) | 18.2507 |
| 2000's | 10 (26.32) | 29.6817 |
| 2010's | 11 (28.95) | 24.3611 |
| 2020's | 4 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Geter, B; Kautz, MA; Riley, AL; Smurthwaite, ST | 1 |
| Calcagnetti, DJ; Calcagnetti, RL; Fanselow, MS | 1 |
| Liebeskind, JC; Lieblich, I; Yirmiya, R | 1 |
| Lieblich, I; Yirmiya, R | 1 |
| Bechara, A; Martin, GM; van der Kooy, D | 1 |
| DeVito, MJ; Wagner, GC | 1 |
| Cooper, SJ | 1 |
| Froehlich, JC; Jing, SL; Krishnan-Sarin, S; Kurtz, DL; Li, TK; Portoghese, PS; Zweifel, M | 1 |
| Keshet, GI; Weinstock, M | 1 |
| Beczkowska, IW; Bodnar, RJ; Bostock, ME; Koch, JE; Leibowitz, SF | 1 |
| Biggs, TA; Myers, RD | 1 |
| Chow, BL; Sellers, EM; Tomkins, DM | 1 |
| Campbell, UC; Carroll, ME; Cosgrove, KP; Rodefer, JS | 1 |
| McNally, GP; Westbrook, RF | 1 |
| Bandy, AL; Lee, AM; Middaugh, LD | 1 |
| Calderon, SN; Hutchinson, AC; Randall, JF; Rice, KC; Riley, AL; Simpson, GR; Zhang, X | 1 |
| Amit, Z; Babinska, I; Campisi, M; Goodwin, FL | 1 |
| Frisina, PG; Sclafani, A | 1 |
| Cummings, R; Eiler, WJ; Foster, KL; Garcia, M; Grey, C; Hawkins, SE; June, HL; Mason, D; McCane, S; McKay, PF; Seyoum, R | 1 |
| Bespalov, A; Danysz, W; Kashkin, V; Malyshkin, A; Neznanova, O; Sukhotina, I; Zakharova, E | 1 |
| Bakalkin, G; Kreek, MJ; Kuzmin, A; Liljequist, S | 1 |
| Gilpin, NW; Ji, D; Koob, GF; Richardson, HN; Rivier, CL | 1 |
| Anker, JJ; Avant, RA; Carroll, ME; Gosnell, BA; Levine, AS; Mitra, A | 1 |
| Brown, ML; Kellar, KJ; Levin, ED; Li, TK; Lumeng, L; McDowell, BE; Paige, MA; Petro, A; Rezvani, AH; Rose, JE; Slade, S; Wells, C; Xiao, Y | 1 |
| Acquas, E; Fois, GR; Muggironi, G; Peana, AT; Vinci, S; Zinellu, M | 1 |
| Nizhnikov, ME; Pautassi, RM; Rahmani, P; Spear, NE; Varlinskaya, EI | 1 |
| Badalia, A; Bodnar, RJ; Duenas, SM; Hossain, M; Rotella, FM; Saeed, S; Sclafani, A; Touzani, K | 1 |
| Banakos, T; Bernal, SY; Bodnar, RJ; Malkusz, DC; Malkusz, G; Mohamed, A; Vongwattanakit, T | 1 |
| Inui, T; Shimura, T | 1 |
| Augier, E; Dulman, RS; Flanigan, M; Heilig, M; Kejun, C; Pincus, A; Rice, KC; Schank, JR; Tapocik, JD | 1 |
| Bodnar, RJ; Huang, D; Kraft, TT; La Magna, S; Lolier, M; Natanova, E; Sclafani, A; Warshaw, D; Yakubov, Y | 1 |
| Anderson, SM; Brunzell, DH; Shelton, KL; Stafford, AM | 1 |
| Kreek, MJ; Zhou, Y | 1 |
| Font, L; Morales, I; Pastor, R; Rodríguez-Borillo, O | 1 |
| Alazzani, M; Alhusban, AY; Alzoubi, KH; Bawaane, A; Khabour, OF; Nuseir, KQ | 1 |
| Fletcher, PJ; Lê, AD; Li, Z; Tabbara, RI | 1 |
| Berglas, E; Bodnar, RJ; Carata, I; Castillo, A; Nashed, M; Pines, R; Roland, M; Sclafani, A | 1 |
38 other study(ies) available for naltrexone and saccharin
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Naloxone as a stimulus in drug discrimination learning: generalization to other opiate antagonists.
Topics: Animals; Cues; Diprenorphine; Discrimination Learning; Female; Generalization, Psychological; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saccharin | 1992 |
Centrally administered opioid antagonists, nor-binaltorphimine, 16-methyl cyprenorphine and MR2266, suppress intake of a sweet solution.
Topics: Animals; Benzomorphans; Drinking Behavior; Female; Glucose; Injections, Intraventricular; Morphinans; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Saccharin | 1990 |
Reduced saccharin preference in CXBK (opioid receptor-deficient) mice.
Topics: Animals; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Naltrexone; Receptors, Opioid; Saccharin; Taste; Taste Threshold | 1988 |
Naltrexone reverses a long term depressive effect of a toxic lithium injection on saccharin preference.
Topics: Animals; Chlorides; Female; Lithium; Lithium Chloride; Morphine; Naltrexone; Rats; Rats, Inbred Strains; Saccharin; Taste | 1987 |
Morphine preexposure attenuates the aversive properties of opiates without preexposure to the aversive properties.
Topics: Animals; Conditioning, Psychological; Male; Morphine; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Reference Values; Saccharin; Taste | 1988 |
Pargyline and naltrexone fail to antagonize the gustatory avoidance response induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Avoidance Learning; Food Preferences; Male; Naltrexone; Pargyline; Pyridines; Rats; Rats, Inbred Strains; Saccharin; Taste | 1986 |
Effects of opiate agonists and antagonists on fluid intake and saccharin choice in the rat.
Topics: Animals; Choice Behavior; Drinking Behavior; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Saccharin | 1983 |
The delta opioid receptor antagonist naltrindole attenuates both alcohol and saccharin intake in rats selectively bred for alcohol preference.
Topics: Alcohol Drinking; Animals; Drinking; Eating; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Saccharin | 1995 |
Maternal naltrexone prevents morphological and behavioral alterations induced in rats by prenatal stress.
Topics: Animals; Choice Behavior; Female; Infusion Pumps, Implantable; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Saccharin; Stress, Physiological | 1995 |
Central opioid receptor subtype antagonists differentially reduce intake of saccharin and maltose dextrin solutions in rats.
Topics: Animals; Drinking Behavior; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Saccharin | 1993 |
Naltrexone and amperozide modify chocolate and saccharin drinking in high alcohol-preferring P rats.
Topics: Alcohol Drinking; Animals; Body Weight; Cacao; Dose-Response Relationship, Drug; Eating; Male; Naltrexone; Narcotic Antagonists; Piperazines; Rats; Rats, Inbred Strains; Saccharin; Serotonin Antagonists; Sweetening Agents; Taste | 1998 |
Effect of naltrexone and its derivatives, nalmefene and naltrindole, on conditioned anticipatory behaviour and saccharin intake in rats.
Topics: Animals; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drinking Behavior; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Saccharin; Sweetening Agents; Taste | 1997 |
Naltrexone pretreatment decreases the reinforcing effectiveness of ethanol and saccharin but not PCP or food under concurrent progressive-ratio schedules in rhesus monkeys.
Topics: Animals; Behavior, Animal; Drug Administration Schedule; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; Food-Drug Interactions; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Phencyclidine; Reinforcement, Psychology; Saccharin; Self Administration | 1999 |
Acute exposure to saccharin reduces morphine analgesia in the the rat: evidence for involvement of N-methyl-D-aspartate and peripheral opioid receptors.
Topics: Analgesia; Analgesics, Opioid; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Saccharin; Sweetening Agents | 2000 |
Ethanol reinforcement in nondeprived mice: effects of abstinence and naltrexone.
Topics: Animals; Ethanol; Food Deprivation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Reinforcement, Psychology; Reward; Saccharin; Self Administration; Solutions; Sucrose; Water Deprivation | 2000 |
Assessment of SNC 80 and naltrindole within a conditioned taste aversion design.
Topics: Animals; Avoidance Learning; Benzamides; Conditioning, Operant; Dose-Response Relationship, Drug; Female; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Rats; Rats, Long-Evans; Receptors, Opioid, delta; Saccharin; Sweetening Agents; Taste | 2000 |
Effects of naltrexone on the intake of ethanol and flavored solutions in rats.
Topics: Alcohol Drinking; Animals; Beverages; Drinking; Drug Combinations; Ethanol; Male; Naltrexone; Narcotic Antagonists; Quinine; Rats; Rats, Long-Evans; Rats, Wistar; Saccharin; Solutions | 2001 |
Naltrexone suppresses the late but not early licking response to a palatable sweet solution: opioid hedonic hypothesis reconsidered.
Topics: Animals; Dose-Response Relationship, Drug; Feeding Behavior; Female; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Reinforcement, Psychology; Saccharin; Sucrose; Sweetening Agents; Taste; Time Factors | 2002 |
Central opioid receptors differentially regulate the nalmefene-induced suppression of ethanol- and saccharin-reinforced behaviors in alcohol-preferring (P) rats.
Topics: Animals; Behavior, Addictive; Brain; Central Nervous System Depressants; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Female; Functional Laterality; Microinjections; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Reinforcement, Psychology; Saccharin | 2004 |
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats.
Topics: Acamprosate; Animals; Choice Behavior; Ethanol; Male; Memantine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taurine | 2004 |
The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking.
Topics: Alcohol Drinking; Alcohols; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Rats; Rats, Wistar; Receptors, Opioid; Saccharin; Self Administration; Spiro Compounds; Sweetening Agents | 2007 |
Effects of naltrexone, duloxetine, and a corticotropin-releasing factor type 1 receptor antagonist on binge-like alcohol drinking in rats.
Topics: Alcohol Deterrents; Animals; Behavior, Addictive; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Ethanol; Male; Naltrexone; Pyrimidines; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Saccharin; Self Administration; Sweetening Agents; Thiophenes | 2008 |
Operant responding for sucrose by rats bred for high or low saccharin consumption.
Topics: Animals; Behavior, Addictive; Conditioning, Operant; Dose-Response Relationship, Drug; Food Preferences; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Rats; Reinforcement Schedule; Saccharin; Self Administration; Sucrose; Sweetening Agents | 2010 |
Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats.
Topics: Animals; Azetidines; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethanol; Male; Naltrexone; Narcotic Antagonists; Nicotine; Nicotinic Agonists; Pyridines; Rats; Receptors, Nicotinic; Reward; Saccharin; Self Administration | 2010 |
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens.
Topics: Acetaldehyde; Animals; Enzyme Activation; Ethanol; Extracellular Signal-Regulated MAP Kinases; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Wistar; Receptors, Opioid, mu; Reinforcement, Psychology; Saccharin; Self Administration | 2011 |
Ontogenetic differences in ethanol's motivational properties during infancy.
Topics: Age Factors; Animals; Animals, Newborn; Avoidance Learning; Conditioning, Operant; Conditioning, Psychological; Ethanol; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Saccharin | 2012 |
Role of NMDA, opioid and dopamine D1 and D2 receptor signaling in the acquisition of a quinine-conditioned flavor avoidance in rats.
Topics: Animals; Avoidance Learning; Benzazepines; Conditioning, Psychological; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Fructose; Male; Naltrexone; Narcotic Antagonists; Quinine; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Saccharin; Signal Transduction; Taste | 2014 |
Evaluation of saccharin intake and expression of fructose-conditioned flavor preferences following opioid receptor antagonism in the medial prefrontal cortex, amygdala or lateral hypothalamus in rats.
Topics: Amygdala; Animals; Conditioning, Psychological; Drinking Behavior; Food Preferences; Fructose; Hypothalamus; Male; Naltrexone; Narcotic Antagonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Saccharin | 2014 |
Delta-opioid receptor blockade in the ventral pallidum increases perceived palatability and consumption of saccharin solution in rats.
Topics: Animals; Avoidance Learning; Basal Forebrain; Conditioning, Psychological; Dose-Response Relationship, Drug; Drinking; Eating; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptors, Opioid, delta; Saccharin; Taste Perception | 2014 |
Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Ethanol; Male; Motivation; Naltrexone; Rats; Rats, Wistar; Reinforcement, Psychology; Reward; Saccharin; Self Administration; Sucrose; Water Deprivation | 2014 |
Dopamine D1 and opioid receptor antagonist-induced reductions of fructose and saccharin intake in BALB/c and SWR inbred mice.
Topics: Animals; Benzazepines; Dietary Carbohydrates; Dose-Response Relationship, Drug; Fructose; Male; Mice, Inbred BALB C; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Receptors, Dopamine D1; Receptors, Opioid; Saccharin; Species Specificity; Sweetening Agents | 2015 |
Oral operant ethanol self-administration in the absence of explicit cues, food restriction, water restriction and ethanol fading in C57BL/6J mice.
Topics: Administration, Oral; Alcohol Drinking; Animals; Conditioning, Operant; Cues; Ethanol; Food Deprivation; Male; Mice; Mice, Inbred C57BL; Naltrexone; Reinforcement, Psychology; Saccharin; Self Administration; Water | 2015 |
Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Drug Evaluation, Preclinical; Drug Tolerance; Female; Male; Mice, Inbred C57BL; Morphinans; Naltrexone; Receptors, Opioid, kappa; Saccharin; Spiro Compounds; Sucrose | 2019 |
Effects of naltrexone on alcohol, sucrose, and saccharin binge-like drinking in C57BL/6J mice: a study with a multiple bottle choice procedure.
Topics: Animals; Behavior, Addictive; Binge Drinking; Binge-Eating Disorder; Ethanol; Male; Mice; Mice, Inbred C57BL; Models, Animal; Naltrexone; Narcotic Antagonists; Saccharin; Self Administration; Sucrose | 2020 |
Saccharin and naltrexone prevent increased pain sensitivity and impaired long-term memory induced by repetitive neonatal noxious stimulation: role of BDNF and enkephalin.
Topics: Analgesics; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Enkephalins; Hippocampus; Male; Maze Learning; Memory, Long-Term; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Rats; Rats, Wistar; Saccharin | 2021 |
The serotonin 2C receptor agonist lorcaserin, alone and in combination with the opioid receptor antagonist naltrexone, attenuates binge-like ethanol drinking.
Topics: Animals; Benzazepines; Binge Drinking; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred C57BL; Models, Animal; Naltrexone; Narcotic Antagonists; Receptor, Serotonin, 5-HT2C; Saccharin; Self Administration; Serotonin 5-HT2 Receptor Agonists | 2021 |
Differential patterns of opioid and dopamine D1 receptor antagonism on nutritive and non-nutritive sweetener intakes in C57BL/6:129 hybrid mice relative to inbred C57BL/6 and 129 mice.
Topics: Analgesics, Opioid; Animals; Dopamine Antagonists; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Non-Nutritive Sweeteners; Receptors, Dopamine D1; Saccharin; Sucrose; Sweetening Agents | 2023 |