naltrexone and piperidines

naltrexone has been researched along with piperidines in 109 studies

Research

Studies (109)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (3.67)	18.7374
1990's	11 (10.09)	18.2507
2000's	46 (42.20)	29.6817
2010's	44 (40.37)	24.3611
2020's	4 (3.67)	2.80

Authors

Authors	Studies
Bilotta, JM; Brackeen, MF; Feldman, PL; James, MK; Leighton, HJ; Schuster, SV	1
Insel, TR; Winslow, JT	1
Linseman, MA	1
Brocklehurst, C; Devia, C; Faust, WB; Moerschbaecher, JM	1
Maas, CL; van Duin, CT; van Miert, AS	1
Herling, S; Solomon, RE; Woods, JH	1
Gates, CC; Haigh, JC	1
Shaw, WN	1
Barrett, TW; Chang, S; Ha, BK; Liu, Y; Saini, P; Whitlock, BB; Wolfe, SA	1
Fuentes, JA; Reche, I; Ruiz-Gayo, M	1
Brooks, DP; Rossi, NF	1
Ha, BK; Saini, P; Whitlock, BB; Wolfe, SA	1
Hough, LB; Li, BY; Nalwalk, JW	1
Maslov, LN; Naryzhnaya, NV; Tam, SW	1
Lowe, J; Mason, DJ; Welch, SP	1
Schwab, CA; Wright, DA	1
Dortch-Carnes, J; Potter, DE	1
Sareen, D	1
Berrendero, F; Maldonado, R	1
Delatte, MS; Moerschbaecher, JM; Winsauer, PJ	1
Kimura, R; Kusaka, T; Urayama, A; Watanabe, Y; Yamada, S	1
Bhardwaj, A; Chen, TY; Hurn, PD; Kirsch, JR; Koehler, RC; Toung, TJK; Traystman, RJ; Zhang, Z	1
Gallate, JE; Mallet, PE; McGregor, IS	1
Chen, RZ; Fong, TM; Huang, RR; MacNeil, DJ; Shen, CP	1
Cantrell, BE; Carroll, FI; Dersch, CM; Fix, SE; Mascarella, SW; Rothman, RB; Thomas, JB; Zimmerman, DM	1
Brown, CH; Leng, G; Ludwig, M	1
Holzer, P	2
Cox, ML; Welch, SP	1
Emmerson, PJ; McKinzie, JH; Mitch, CH; Statnick, MA; Surface, PL; Suter, TM	1
Dehpour, AR; Hajrasouliha, AR; Homayoun, H; Moezi, L; Sadeghipour, H; Samini, M; Shafaroodi, H; Tavakoli, S	1
Gallate, JE; McGregor, IS	1
Fantegrossi, WE; Koreeda, M; Kugle, KM; Valdes, LJ; Woods, JH	1
Gackenheimer, SL; Gehlert, DR; Mitch, CH; Pintar, JE; Quimby, SJ; Statnick, MA; Suter, TM; Wheeler, WJ	1
Mohan, S; Stevens, CW	1
Sinatra, RS	1
Carter, S	1
Saclarides, TJ	1
Dehaven-Hudkins, DL; Fukuda, H; Hicks, GA; Mantyh, CR; Pappas, TN; Suenaga, K; Takahashi, T; Tsuchida, D	1
Thompson, CA	1
Kordik, CP; Levin, ED; Overstreet, DH; Reitz, AB; Rezvani, AH; Rosenthal, DI; Vaidya, AH	1
Braida, D; Gori, E; Guerini-Rocco, C; Limonta, V; Pegorini, S; Sala, M; Zani, A	1
Beattie, DT; Cheruvu, M; Johnson-Rabidoux, S; Kaufman, E; Mai, N; O'Keefe, M; Peterson, C; Vickery, R	1
Chen, TY; Gomery, P; Israel, R; Rosow, CE; Stambler, N; Stefanovich, P	1
Deng, C; Huang, XF; South, T	1
Thomas, J	1
Dehpour, AR; Ghasemi, M; Shafaroodi, H	1
Jackson, KC; Neyens, R	1
Braida, D; Capurro, V; Fadda, P; Fratta, W; Gori, E; Limonta, V; Mascia, P; Parolaro, D; Rubino, T; Sala, M; Zani, A	1
DeHaven, RN; DeHaven-Hudkins, DL; Little, PJ; Techner, LM	1
Chen, Q; Dong, L; Fu, CY; Ni, JM; Wang, R; Zhao, YL	1
Boyce, D; Carr, DB; McNicol, ED; Schumann, R	1
Bahremand, A; Dehpour, AR; Ghasemi, M; Gholizadeh, S; Nasrabady, SE; Shafaroodi, H	1
Meerpohl, JJ; Timmer, A	1
Becker, G; Blum, HE	1
Bradbury, FA; Carroll, FI; Divin, MF; Traynor, JR	1
Fantegrossi, WE; Galuska, CM; Ko, MC; Prinssen, EP; Wichmann, J; Woods, JH	1
Delaney, CP; Stulberg, JJ; Zeinali, F	1
Braida, D; Capurro, V; Parolaro, D; Rubino, T; Sala, M; Viganò, D; Zani, A	1
Corley, G; Rawls, SM	1
Di Paolo, T; Grégoire, L; Lévesque, D; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P; Tamim, MK	1
Frost, EA	1
Irwin, MG; Jiang, LL; Li, R; Wong, GT	1
Calò, G; Guerrini, R; Hu, E; Ko, MC	1
Beardsley, PM; Carroll, FI; Howard, JL; Pollard, GT	1
Cabañero, D; Campillo, A; García-Nogales, P; Puig, MM; Romero, A	1
Fish, EW; Heilig, M; Krouse, MC; Malanga, CJ; Robinson, JE; Thorsell, A	1
Bell, RL; Dhaher, R; Hauser, SR; McBride, WJ; McKinzie, DL; Rodd, ZA; Toalston, JE	1
Brosnan, RJ; Ilkiw, JE; Pypendop, BH	1
Jeong, C; Jeong, H; Jeong, S; Kim, SJ; Lee, J; Lee, S; Yoo, KY	1
Bidlack, JM; Dean, RL; Deaver, DR; Eyerman, D; Todtenkopf, MS; Turncliff, RZ	1
Fleckenstein, J; Napadow, V; Nowak-Machen, M; Pfab, F	1
Magnuson, B; Thompson, M	1
Bakhle, YS; Camêlo, VM; Dos Reis, WG; Faraco, A; Francischi, JN; Paiva-Lima, P; Rezende, RM	1
Carroll, FI; Cherezov, V; Han, GW; Huang, XP; Katritch, V; Liu, W; Mascarella, SW; Mileni, M; Mosier, PD; Roth, BL; Stevens, RC; Thompson, AA; Vardy, E; Wacker, D; Westkaemper, RB; Wu, H	1
Devi, LA; Filizola, M	1
Béguin, C; Berry, LM; Carlezon, WA; Carroll, FI; Cohen, BM; Munro, TA; Van't Veer, A; Zhao, Z	1
Shi, C; Wang, S; Xie, X; Xue, G; Zhang, L; Zhang, R	1
Carlsson, A; Feltmann, K; Franck, J; Fredriksson, I; Holst, S; Schilström, B; Steensland, P	1
Arulselvan, P; Fakurazi, S; Hairuszah, I; Hidayat, MT; Moklas, MAM; Shamima, AR	1
Bloom, A; Gras, B; Lembo, A; Magge, S	1
Arduino, C; Benedetti, F; Blanchard, C; Thoen, W; Vighetti, S	1
Armstrong, SR; Beattie, DT; Campbell, CB; Hegde, SS; Long, DD; Richardson, CL; Tsuruda, PR; Vickery, RG	1
Armstrong, SR; Beattie, DT; Long, DD; Tsuruda, PR; Vickery, RG	1
Ahlstrand, R; Magnuson, A; Savilampi, J; Wattwil, M	1
Brenner, DM; Ford, AC; Schoenfeld, PS	1
McCarberg, BH	1
Béguin, C; Carlezon, WA; Carroll, FI; Cohen, BM; Colabufo, NA; Huang, XP; Inglese, C; Munro, TA; Perrone, MG; Roth, BL; Van't Veer, A	1
Bailey, SJ; Casal-Dominguez, JJ; Clark, MJ; Furkert, D; Husbands, SM; Ostovar, M; Teintang, L; Traynor, JR	1
Rodriguez, RW	1
Ko, MC; Lagorio, CH; Sukhtankar, DD	1
Hu, N; Li, Y; Shu, R; Wang, C; Wang, G; Wang, H; Xie, K; Yu, Y; Zhang, L	1
Ehrich, E; Sellers, EM; Shram, MJ; Silverman, B; Turncliff, R	1
Ahmedzai, SH; Boland, JW	1
Lindsey, AM; Prinssen, EP; Rice, KC; Saccone, PA; Sulima, A; Wichmann, J; Woods, JH; Zelenock, KA	1
Coggiano, M; Hiranita, T; Katz, JL; Mereu, M; Quarterman, JC; Tanda, G	1
Ciccocioppo, R; de Guglielmo, G; Journigan, VB; Kallupi, M; Shen, Q; Yasuda, D; Zaveri, NT	1
Bradberry, CW; Panlilio, LV; Schindler, CW; Secci, ME	1
Asahi, H; Inoue, SI; Kobayashi, F; Kunigo, K; Niikura, M; Sendo, F; Suzuki, Y	1
Murphy, JA; Sheridan, EA	1
Cottone, P; Mancino, S; Moore, CF; Sabino, V; Schlain, GS	1
Garcia, JM; Shamliyan, TA	1
Candy, B; Jones, L; Larkin, PJ; Stone, P; Vickerstaff, V	1
Amiri, S; Dehpour, AR; Ghasemi, M; Haj-Mirzaian, A; Hassanipour, M; Khoshnoodi, M; Ostadhadi, S; Shafaroodi, H; Sharifzadeh, M; Shirzadian, A	1
Bäckström, P; Carroll, FI; Eteläinen, T; Kiianmaa, K; Oinio, V; Piepponen, P; Raasmaja, A; Uhari-Väänänen, J	1
Baamonde, A; González-Rodríguez, S; Lastra, A; Machelska, H; Menéndez, L; Seitz, V; Stein, C	1
Berghold, A; Horvath, K; Jeitler, K; Krenn, C; Semlitsch, T; Siebenhofer, A; Winterholer, S	1
Ballet, S; Bermudez, M; De Neve, J; Dumitrascuta, M; Spetea, M; Trovato, O; Wolber, G	1
Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S	1

Reviews

22 review(s) available for naltrexone and piperidines

Article	Year
Neuroprotective agents in acute ischemic stroke. The Journal of the Association of Physicians of India, 2002, Volume: 50 Topics: Acute Disease; Adult; Aged; Animals; Antioxidants; Calcium Channel Blockers; Chlormethiazole; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Forecasting; GABA Modulators; Guanidines; Humans; Imidazoles; Middle Aged; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Pipecolic Acids; Piperidines; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Stroke; Thiazoles	2002
Opioids and opioid receptors in the enteric nervous system: from a problem in opioid analgesia to a possible new prokinetic therapy in humans. Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3 Topics: Analgesics, Opioid; Animals; Constipation; Enteric Nervous System; Gastrointestinal Motility; Humans; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid	2004
Peripherally acting mu-opioid-receptor antagonists and the connection between postoperative ileus and pain management: The anesthesiologist's view and beyond. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2006, Volume: 21, Issue:2A Suppl Topics: Analgesia; Analgesics, Opioid; Anesthesia; Anesthesiology; Anti-Inflammatory Agents, Non-Steroidal; Attitude of Health Personnel; Blood-Brain Barrier; Clinical Trials, Phase III as Topic; Humans; Ileus; Length of Stay; Naltrexone; Narcotic Antagonists; Nurse's Role; Outcome Assessment, Health Care; Pain, Postoperative; Patient Satisfaction; Piperidines; Postanesthesia Nursing; Postoperative Care; Postoperative Complications; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Risk Factors	2006
The surgical team and outcomes management: focus on postoperative ileus. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2006, Volume: 21, Issue:2A Suppl Topics: Analgesics, Opioid; Causality; Cost of Illness; Hospital Costs; Humans; Ileus; Incidence; Laparotomy; Length of Stay; Naltrexone; Narcotic Antagonists; Nurse's Role; Outcome Assessment, Health Care; Pain, Postoperative; Patient Care Team; Patient Satisfaction; Piperidines; Postanesthesia Nursing; Postoperative Care; Postoperative Complications; Professional Role; Quaternary Ammonium Compounds; Time Factors; Total Quality Management	2006
Current choices--good or bad--for the proactive management of postoperative ileus: A surgeon's view. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2006, Volume: 21, Issue:2A Suppl Topics: Analgesia, Epidural; Analgesics, Opioid; Attitude of Health Personnel; Choice Behavior; Enteral Nutrition; Evidence-Based Medicine; General Surgery; Humans; Ileus; Intubation, Gastrointestinal; Laparoscopy; Laparotomy; Length of Stay; Naltrexone; Narcotic Antagonists; Outcome Assessment, Health Care; Patient Care Team; Patient Selection; Piperidines; Postoperative Care; Postoperative Complications; Practice Guidelines as Topic; Quaternary Ammonium Compounds; Risk Factors	2006
Cancer-related constipation. Current oncology reports, 2007, Volume: 9, Issue:4 Topics: Alprostadil; Constipation; Fatty Acids; Gastrointestinal Agents; Humans; Indoles; Lubiprostone; Naltrexone; Narcotic Antagonists; Neoplasms; Piperidines; Quaternary Ammonium Compounds; Serotonin Receptor Agonists	2007
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus. Journal of pain & palliative care pharmacotherapy, 2007, Volume: 21, Issue:2 Topics: Analgesics, Opioid; Gastrointestinal Transit; Humans; Ileus; Intestinal Diseases; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds	2007
The involvement of the mu-opioid receptor in gastrointestinal pathophysiology: therapeutic opportunities for antagonism at this receptor. Pharmacology & therapeutics, 2008, Volume: 117, Issue:1 Topics: Analgesics, Opioid; Animals; Clinical Trials as Topic; Drug Evaluation, Preclinical; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu	2008
Mu-opioid antagonists for opioid-induced bowel dysfunction. The Cochrane database of systematic reviews, 2008, Apr-16, Issue:2 Topics: Constipation; Defecation; Gastrointestinal Agents; Humans; Intestinal Diseases; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu	2008
[News from the cochrane library: mu opioid antagonists for opioid-induced bowel dysfunction]. Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:9 Topics: Analgesics, Opioid; Clinical Trials as Topic; Constipation; Gastrointestinal Transit; Humans; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu	2008
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus. Lancet (London, England), 2009, Apr-04, Volume: 373, Issue:9670 Topics: Analgesics, Opioid; Blood-Brain Barrier; Drug Approval; Europe; Humans; Ileus; Myocardial Infarction; Naltrexone; Narcotic Antagonists; Patient Selection; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds; Research Design; Safety; United States; United States Food and Drug Administration	2009
Opioid receptors in the gastrointestinal tract. Regulatory peptides, 2009, Jun-05, Volume: 155, Issue:1-3 Topics: Animals; Constipation; Gastrointestinal Tract; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid	2009
Pharmacological management of postoperative ileus. Canadian journal of surgery. Journal canadien de chirurgie, 2009, Volume: 52, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bisacodyl; Cathartics; Cisapride; Dihydroergotamine; Humans; Ileus; Inflammation; Naltrexone; Neostigmine; Parasympathomimetics; Piperidines; Postoperative Complications; Propranolol; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Serotonin Receptor Agonists	2009
Alternatives to prokinetics to move the pylorus and colon. Current opinion in clinical nutrition and metabolic care, 2012, Volume: 15, Issue:2 Topics: Acupuncture Therapy; Animals; Colon; Complementary Therapies; Enema; Gastrointestinal Agents; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Laxatives; Naltrexone; Narcotic Antagonists; Piperidines; Probiotics; Pylorus; Quaternary Ammonium Compounds	2012
Motility disorders of the colon and rectum. Current opinion in gastroenterology, 2013, Volume: 29, Issue:1 Topics: Constipation; Diet; Dipeptides; Diverticulosis, Colonic; Gastrointestinal Agents; Gastrointestinal Transit; Humans; Naltrexone; Narcotic Antagonists; Peptides; Piperidines; Quaternary Ammonium Compounds; Rectal Diseases; Thiazepines; Tryptophan Hydroxylase	2013
Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and meta-analysis. The American journal of gastroenterology, 2013, Volume: 108, Issue:10 Topics: Alprostadil; Analgesics, Opioid; Benzofurans; Constipation; Female; Gastrointestinal Agents; Humans; Lubiprostone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu	2013
Overview and treatment of opioid-induced constipation. Postgraduate medicine, 2013, Volume: 125, Issue:4 Topics: Analgesics, Opioid; Combined Modality Therapy; Constipation; Delayed-Action Preparations; Diet Therapy; Humans; Laxatives; Life Style; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds	2013
Constipation: opioid antagonists in people prescribed opioids. BMJ clinical evidence, 2015, Sep-11, Volume: 2015 Topics: Analgesics, Opioid; Constipation; Gastrointestinal Agents; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Treatment Outcome	2015
Evidence Based Review of Pharmacotherapy for Opioid-Induced Constipation in Noncancer Pain. The Annals of pharmacotherapy, 2018, Volume: 52, Issue:4 Topics: Analgesics, Opioid; Chronic Pain; Constipation; Evidence-Based Practice; Humans; Laxatives; Lubiprostone; Morphinans; Naltrexone; Narcotic Antagonists; Piperidines; Polyethylene Glycols; Quaternary Ammonium Compounds; Randomized Controlled Trials as Topic	2018
Management of Opioid-Induced Constipation in Patients with Malignancy. The American journal of medicine, 2018, Volume: 131, Issue:9 Topics: Analgesics, Opioid; Cancer Pain; Constipation; Enema; Gastrointestinal Agents; Gastrostomy; Humans; Laxatives; Morphinans; Naltrexone; Piperidines; Polyethylene Glycols; Practice Guidelines as Topic; Quaternary Ammonium Compounds	2018
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care. The Cochrane database of systematic reviews, 2018, 06-05, Volume: 6 Topics: Constipation; Defecation; Female; Gastrointestinal Agents; Humans; Intestinal Diseases; Male; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Neoplasms; Opioid-Related Disorders; Oxycodone; Palliative Care; Piperidines; Quaternary Ammonium Compounds; Randomized Controlled Trials as Topic; Receptors, Opioid, mu	2018
Long-term effects of weight-reducing drugs in people with hypertension. The Cochrane database of systematic reviews, 2021, 01-17, Volume: 1 Topics: Adult; Anti-Obesity Agents; Appetite Depressants; Bias; Blood Pressure; Body Weight; Bupropion; Diet, Reducing; Drug Combinations; Female; Fructose; Humans; Hypertension; Lactones; Male; Middle Aged; Naltrexone; Orlistat; Phentermine; Piperidines; Pyrazoles; Randomized Controlled Trials as Topic; Safety-Based Drug Withdrawals; Time; Topiramate	2021

Trials

5 trial(s) available for naltrexone and piperidines

Article	Year
Reversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexone. Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:1 Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Humans; Infusions, Intravenous; Male; Middle Aged; Miosis; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Remifentanil; Treatment Outcome; Urinary Bladder; Urinary Retention; Urination	2007
Use of naltrexone to antagonize high doses of remifentanil in cats: a dose-finding study. Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:6 Topics: Analgesics, Opioid; Animals; Cat Diseases; Cats; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Overdose; Female; Hyperkinesis; Naltrexone; Narcotic Antagonists; Piperidines; Prospective Studies; Remifentanil	2011
Pain as a reward: changing the meaning of pain from negative to positive co-activates opioid and cannabinoid systems. Pain, 2013, Volume: 154, Issue:3 Topics: Adult; Arm; Attitude to Health; Cannabinoid Receptor Antagonists; Culture; Double-Blind Method; Female; Humans; Ischemia; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Persuasive Communication; Physical Endurance; Piperidines; Pyrazoles; Receptors, Cannabinoid; Reward; Rimonabant; Suggestion; Time Factors; Young Adult	2013
Effects of remifentanil on the esophagogastric junction and swallowing. Acta anaesthesiologica Scandinavica, 2013, Volume: 57, Issue:8 Topics: Adult; Anesthetics, Intravenous; Cross-Over Studies; Data Interpretation, Statistical; Deglutition; Double-Blind Method; Esophagogastric Junction; Female; Humans; Male; Manometry; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Remifentanil; Stomach; Young Adult	2013
Use of Remifentanil in a Novel Clinical Paradigm to Characterize Onset and Duration of Opioid Blockade by Samidorphan, a Potent μ-Receptor Antagonist. Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:3 Topics: Adult; Analgesics, Opioid; Double-Blind Method; Female; Humans; Male; Middle Aged; Miosis; Naltrexone; Narcotic Antagonists; Piperidines; Receptors, Opioid, mu; Remifentanil; Visual Analog Scale; Young Adult	2015

Other Studies

82 other study(ies) available for naltrexone and piperidines

Article	Year
Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Alkylation; Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; Kinetics; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil; Vas Deferens	1991
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:1 Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal	1990
Central vs. peripheral mediation of opioid effects on alcohol consumption in free-feeding rats. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2 Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Loperamide; Male; Morphine; Naltrexone; Narcotic Antagonists; Piperidines; Polysorbates; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Time Factors	1989
Effects of kappa agonists and dexoxadrol on the acquisition of conditional discriminations in monkeys. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:2 Topics: Analgesics; Animals; Benzomorphans; Conditioning, Psychological; Cyclazocine; Dioxolanes; Dioxoles; Discrimination Learning; Dose-Response Relationship, Drug; Erythrocebus patas; Ethylketocyclazocine; Female; Macaca fascicularis; Male; Naltrexone; Piperidines; Receptors, Opioid; Receptors, Opioid, kappa	1987
Loperamide: evidence for a centrally mediated opioid effect on rumen motility in conscious goats and sheep. Journal of veterinary pharmacology and therapeutics, 1986, Volume: 9, Issue:1 Topics: Animals; Domperidone; Gastrointestinal Motility; Goats; Kinetics; Loperamide; Naltrexone; Narcotics; Piperidines; Rumen; Sheep	1986
Discriminative stimulus effects of dextrorphan in pigeons. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3 Topics: Animals; Bemegride; Binding Sites; Columbidae; Dextrorphan; Dioxolanes; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Generalization, Stimulus; Morphinans; Naltrexone; Pentobarbital; Piperidines; Stereoisomerism; Structure-Activity Relationship	1983
Capture of wood bison (Bison bison athabascae) using carfentanil-based mixtures. Journal of wildlife diseases, 1995, Volume: 31, Issue:1 Topics: Analgesics, Opioid; Animals; Bison; Diprenorphine; Drug Combinations; Female; Fentanyl; Hypnotics and Sedatives; Immobilization; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Northwest Territories; Piperidines; Tranquilizing Agents; Xylazine	1995
Long-term treatment of obese Zucker rats with LY255582 and other appetite suppressants. Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3 Topics: Albuterol; Animals; Appetite Depressants; Cyclohexanes; Dextroamphetamine; Drug Tolerance; Eating; Endorphins; Female; Fenfluramine; Injections, Subcutaneous; Male; Naltrexone; Obesity; Piperidines; Rats; Rats, Zucker; Weight Gain	1993
Initial characterization and autoradiographic localization of a novel sigma/opioid binding site in immune tissues. Journal of neuroimmunology, 1996, Volume: 67, Issue:2 Topics: Animals; Anticonvulsants; Autoradiography; Binding Sites; Binding, Competitive; Brain Chemistry; Cytochrome P-450 Enzyme System; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Monoamine Oxidase; Naltrexone; Narcotic Antagonists; Narcotics; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spleen; Tritium	1996
A role for central cannabinoid and opioid systems in peripheral delta 9-tetrahydrocannabinol-induced analgesia in mice. European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3 Topics: Analgesics; Animals; Central Nervous System; Dose-Response Relationship, Drug; Dronabinol; Dynorphins; Injections, Intravenous; Male; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Peripheral Nervous System; Piperidines; Pyrazoles; Reaction Time; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid; Rimonabant	1996
kappa-Opioid agonist inhibition of osmotically induced AVP release: preferential action at hypothalamic sites. The American journal of physiology, 1996, Volume: 270, Issue:2 Pt 1 Topics: Animals; Arginine Vasopressin; Culture Techniques; Hypothalamus; Male; Naltrexone; Narcotic Antagonists; Osmotic Pressure; Piperidines; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Receptors, Opioid, kappa	1996
Differential localization of three distinct binding sites for sigma receptor ligands in rat spleen. Journal of neuroimmunology, 1997, Volume: 72, Issue:1 Topics: Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Autoradiography; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Image Processing, Computer-Assisted; Ligands; Male; Naltrexone; Narcotic Antagonists; Pentazocine; Phenazocine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Spleen; Tritium	1997
Effects of naltrexone and histamine antagonists on the antinociceptive activity of the cimetidine analog SKF92374 in rats. Brain research, 1997, Feb-14, Volume: 748, Issue:1-2 Topics: Analgesics, Non-Narcotic; Animals; Cimetidine; Histamine Agonists; Histamine Antagonists; Male; Methylhistamines; Naltrexone; Narcotic Antagonists; Nociceptors; Piperidines; Rats; Rats, Sprague-Dawley; Stereoisomerism	1997
Ligands for opioid and sigma-receptors improve cardiac electrical stability in rat models of post-infarction cardiosclerosis and stress. Life sciences, 1999, Volume: 65, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; beta-Endorphin; Disease Models, Animal; Dynorphins; Enkephalin, Leucine-2-Alanine; Heart; Immobilization; Ligands; Morphine; Myocardial Infarction; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Piperidines; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Stress, Physiological; Ventricular Fibrillation	1999
Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception. European journal of pharmacology, 1999, Aug-13, Volume: 378, Issue:3 Topics: Analgesics; Animals; Cannabinoids; Cyclohexanols; Dimethyl Sulfoxide; Dronabinol; Dynorphins; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant	1999
Intraoperative high-dose remifentanil in a patient on naltrexone therapy. Anaesthesia and intensive care, 2000, Volume: 28, Issue:6 Topics: Aged; Analgesics, Opioid; Arteriovenous Fistula; Debridement; Female; Foot Ulcer; Humans; Intraoperative Complications; Naltrexone; Narcotic Antagonists; Piperidines; Remifentanil; Substance Withdrawal Syndrome	2000
Inhibition of cAMP accumulation by kappa-receptor activation in isolated iris-ciliary bodies: role of phosphodiesterase and protein kinase C. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Benzophenanthridines; Ciliary Body; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; In Vitro Techniques; Iris; Naltrexone; Narcotic Antagonists; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Protein Kinase C; Pyrrolidines; Rabbits; Receptors, Opioid, kappa; Rolipram	2002
Involvement of the opioid system in the anxiolytic-like effects induced by Delta(9)-tetrahydrocannabinol. Psychopharmacology, 2002, Volume: 163, Issue:1 Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Darkness; Dronabinol; Endorphins; Light; Male; Mice; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rimonabant	2002
Tolerance to the disruptive effects of Delta(9)-THC on learning in rats. Pharmacology, biochemistry, and behavior, 2002, Volume: 74, Issue:1 Topics: Animals; Color Perception; Conditioning, Operant; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Hallucinogens; Learning; Male; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Reinforcement Schedule; Rimonabant	2002
In vitro and ex vivo effects of a selective nociceptin/orphanin FQ (N/OFQ) peptide receptor antagonist, CompB, on specific binding of [3H]N/OFQ and [35S]GTPgammaS in rat brain and spinal cord. British journal of pharmacology, 2003, Volume: 139, Issue:8 Topics: Animals; Benzimidazoles; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Guanosine Triphosphate; Injections, Intravenous; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord	2003
Kappa-opioid receptor selectivity for ischemic neuroprotection with BRL 52537 in rats. Anesthesia and analgesia, 2003, Volume: 97, Issue:6 Topics: Animals; Behavior, Animal; Cerebral Cortex; Cranial Nerves; Functional Laterality; Gait; Hemodynamics; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Male; Middle Cerebral Artery; Muscle Tonus; Naltrexone; Neuroprotective Agents; Pain; Piperidines; Putamen; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Weight Loss	2003
Combined low dose treatment with opioid and cannabinoid receptor antagonists synergistically reduces the motivation to consume alcohol in rats. Psychopharmacology, 2004, Volume: 173, Issue:1-2 Topics: Alcohol Drinking; Animals; Cannabinoids; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Male; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Rimonabant	2004
Synergistic effects of cannabinoid inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice. Brain research, 2004, Mar-05, Volume: 999, Issue:2 Topics: Animals; Appetite Regulation; Body Weight; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Drug Synergism; Homeostasis; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Obesity; Opioid Peptides; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1	2004
Importance of phenolic address groups in opioid kappa receptor selective antagonists. Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4 Topics: Animals; Binding, Competitive; Brain; In Vitro Techniques; Naltrexone; Phenols; Piperidines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Tetrahydroisoquinolines	2004
Temporal dissociation of the feedback effects of dendritically co-released peptides on rhythmogenesis in vasopressin cells. Neuroscience, 2004, Volume: 124, Issue:1 Topics: Action Potentials; Animals; Antidiuretic Hormone Receptor Antagonists; Dendrites; Dynorphins; Feedback, Physiological; Female; Naltrexone; Narcotic Antagonists; Periodicity; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Supraoptic Nucleus; Vasopressins	2004
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat. European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3 Topics: Animals; Arthritis, Experimental; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Dronabinol; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Freund's Adjuvant; Injections, Intradermal; Injections, Intraperitoneal; Male; Morphine; Mycobacterium; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid; Rimonabant	2004
Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists. European journal of pharmacology, 2004, Jun-28, Volume: 494, Issue:2-3 Topics: Animals; Appetite Depressants; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cyclohexanes; Diprenorphine; Dose-Response Relationship, Drug; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Naltrexone; Narcotic Antagonists; Piperidines; Radioligand Assay; Rats; Rats, Zucker; Receptors, Opioid; Receptors, Opioid, delta; Sodium	2004
The interaction of cannabinoids and opioids on pentylenetetrazole-induced seizure threshold in mice. Neuropharmacology, 2004, Volume: 47, Issue:3 Topics: Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentylenetetrazole; Piperidines; Pyrazoles; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Opioid; Seizures; Statistics, Nonparametric; Time Factors	2004
Rats on the grog: novel pharmacotherapies for alcohol craving. Addictive behaviors, 2004, Volume: 29, Issue:7 Topics: Alcoholism; Animals; Baclofen; Beer; Behavior, Addictive; Cannabinoid Receptor Antagonists; Corticotropin-Releasing Hormone; Humans; Models, Animal; Naltrexone; Narcotic Antagonists; Neuropeptide Y; Piperidines; Pyrazoles; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, GABA-B; Research Design; Rimonabant	2004
Kappa-opioid receptor-mediated effects of the plant-derived hallucinogen, salvinorin A, on inverted screen performance in the mouse. Behavioural pharmacology, 2005, Volume: 16, Issue:8 Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzeneacetamides; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Psychotropic Drugs; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil	2005
Localization of opioid receptor antagonist [3H]-LY255582 binding sites in mouse brain: comparison with the distribution of mu, delta and kappa binding sites. Neuropeptides, 2005, Volume: 39, Issue:6 Topics: Animals; Autoradiography; Binding Sites; Brain; Cyclohexanes; Mice; Mice, Knockout; Molecular Structure; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium	2005
Systemic and spinal administration of the mu opioid, remifentanil, produces antinociception in amphibians. European journal of pharmacology, 2006, Mar-18, Volume: 534, Issue:1-3 Topics: Acetic Acid; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Injections, Subcutaneous; Models, Animal; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Piperidines; Rana pipiens; Receptors, Opioid, mu; Remifentanil; Time Factors	2006
The selective mu opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats. Brain research, 2006, Aug-02, Volume: 1102, Issue:1 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Transit; Ileus; Laparotomy; Male; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley	2006
Pain management research goes beyond the obvious. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2006, Dec-01, Volume: 63, Issue:23 Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Constipation; Humans; Naltrexone; Narcotic Antagonists; Pain; Piperidines; Pyridines; Quaternary Ammonium Compounds; Receptors, Opioid, mu	2006
Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats. Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:1 Topics: Acute Disease; Alcohol Drinking; Animals; Anti-Anxiety Agents; Chronic Disease; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Injections, Intraperitoneal; Male; Naltrexone; Narcotic Antagonists; Piperidines; Pyridines; Rats	2007
Hallucinatory and rewarding effect of salvinorin A in zebrafish: kappa-opioid and CB1-cannabinoid receptor involvement. Psychopharmacology, 2007, Volume: 190, Issue:4 Topics: Animals; Behavior, Addictive; Behavior, Animal; Conditioning, Psychological; Diterpenes; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Hallucinogens; Models, Animal; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Reinforcement, Psychology; Reproducibility of Results; Reward; Rimonabant; Swimming; Time Factors; Zebrafish	2007
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone. Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:3 Topics: Analgesics, Opioid; Animals; Benzeneacetamides; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Piperidines; Pyrrolidines; Quaternary Ammonium Compounds; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; Transfection	2007
AM 251 and beta-Funaltrexamine reduce fat intake in a fat-preferring strain of mouse. Behavioural brain research, 2007, Jul-19, Volume: 181, Issue:1 Topics: Analysis of Variance; Animals; Choice Behavior; Dietary Fats; Eating; Energy Intake; Food Preferences; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Phenotype; Piperidines; Pyrazoles	2007
Elevation of pentylenetetrazole-induced seizure threshold in cholestatic mice: interaction between opioid and cannabinoid systems. Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:7 Pt 2 Topics: Animals; Anticonvulsants; Bile Ducts; Cannabinoid Receptor Modulators; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Ligation; Male; Mice; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pentylenetetrazole; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid; Seizures; Time Factors	2008
Involvement of kappa-opioid and endocannabinoid system on Salvinorin A-induced reward. Biological psychiatry, 2008, Feb-01, Volume: 63, Issue:3 Topics: Analysis of Variance; Animals; Antioxidants; Behavior, Animal; Cannabinoid Receptor Modulators; Conditioning, Operant; Diterpenes; Diterpenes, Clerodane; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Endocannabinoids; Male; Microdialysis; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reward; Rimonabant; Self Administration	2008
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4-11), mammalian tachykinin peptides, on the modulation of pain in mice. Brain, behavior, and immunity, 2008, Volume: 22, Issue:6 Topics: Analgesics; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Humans; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Tachykinins; Tropanes	2008
The cannabinoid anticonvulsant effect on pentylenetetrazole-induced seizure is potentiated by ultra-low dose naltrexone in mice. Epilepsy research, 2008, Volume: 81, Issue:1 Topics: Animals; Anticonvulsants; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoids; Convulsants; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Injections, Intraperitoneal; Male; Mice; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Piperidines; Pyrazoles; Seizures	2008
Neutral antagonist activity of naltrexone and 6beta-naltrexol in naïve and opioid-dependent C6 cells expressing a mu-opioid receptor. British journal of pharmacology, 2009, Volume: 156, Issue:7 Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Line; Cell Line, Tumor; Cyclic AMP; Drug Inverse Agonism; Drug Partial Agonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Morphine; Naloxone; Naltrexone; Peptide Fragments; Piperidines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin	2009
Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:9 Topics: Alfentanil; Analgesics, Opioid; Animals; Behavior, Animal; Benzimidazoles; Capsaicin; Central Nervous System Agents; Dose-Response Relationship, Drug; Female; Hot Temperature; Imidazoles; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Pain; Piperidines; Pruritus; Receptors, Opioid; Receptors, Opioid, mu; Reinforcement, Psychology; Respiratory Insufficiency; Spiro Compounds	2009
Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia divinorum, in rodents. British journal of pharmacology, 2009, Volume: 157, Issue:5 Topics: Amidohydrolases; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Binding, Competitive; Brain; Cyclohexanols; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Emotions; Injections, Subcutaneous; Male; Mice; Models, Animal; Motor Activity; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Salvia; Swimming	2009
Opioid, cannabinoid CB1 and NOP receptors do not mediate APAP-induced hypothermia in rats. Pharmacology, biochemistry, and behavior, 2009, Volume: 92, Issue:3 Topics: Acetaminophen; Aminoquinolines; Animals; Benzamides; Body Temperature; Hypothermia, Induced; Male; Naltrexone; Nociceptin Receptor; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid; Rimonabant	2009
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides. Neuropharmacology, 2010, Volume: 58, Issue:1 Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors	2010
Preventing paralytic ileus: can the anesthesiologist help. Middle East journal of anaesthesiology, 2009, Volume: 20, Issue:2 Topics: Analgesics, Opioid; Anesthetics; Gastrointestinal Agents; Humans; Intestinal Pseudo-Obstruction; Intubation, Gastrointestinal; Naltrexone; Piperidines; Postoperative Complications; Preoperative Care; Quaternary Ammonium Compounds	2009
Remifentanil post-conditioning attenuates cardiac ischemia-reperfusion injury via kappa or delta opioid receptor activation. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:4 Topics: Analgesics, Opioid; Animals; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil; Somatostatin	2010
Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112. Pain, 2010, Volume: 148, Issue:1 Topics: Analgesics; Animals; Benzimidazoles; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Macaca mulatta; Male; Morphine; Naltrexone; Nociceptin; Opioid Peptides; Pain Measurement; Pain Threshold; Piperidines	2010
Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diure Psychopharmacology, 2010, Volume: 210, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cocaine-Related Disorders; Diuresis; Dose-Response Relationship, Drug; Male; Naltrexone; Pain; Piperidines; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Self Administration; Tetrahydroisoquinolines	2010
Delayed postoperative latent pain sensitization revealed by the systemic administration of opioid antagonists in mice. European journal of pharmacology, 2011, Apr-25, Volume: 657, Issue:1-3 Topics: Animals; Dizocilpine Maleate; Dynorphins; Hyperalgesia; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Piperidines; Postoperative Complications; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Remifentanil; Spinal Cord	2011
Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism. Psychopharmacology, 2012, Volume: 220, Issue:1 Topics: Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Male; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Reinforcement, Psychology; Reward; Substance P	2012
Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats. Alcohol (Fayetteville, N.Y.), 2012, Volume: 46, Issue:1 Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Conditioning, Operant; Cyclohexanes; Drug-Seeking Behavior; Ethanol; Extinction, Psychological; Female; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Secondary Prevention	2012
Neuroprotective effects of remifentanil against transient focal cerebral ischemia in rats. Journal of neurosurgical anesthesiology, 2012, Volume: 24, Issue:1 Topics: Anesthetics, Intravenous; Animals; Blood Pressure; Blotting, Western; Carbon Dioxide; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Interleukin-6; Ischemic Attack, Transient; Male; Mitogen-Activated Protein Kinases; Naltrexone; Narcotic Antagonists; Nervous System Diseases; Neuroprotective Agents; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Reperfusion Injury; Tumor Necrosis Factor-alpha	2012
Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats. Pharmacology, biochemistry, and behavior, 2012, Volume: 100, Issue:3 Topics: Administration, Oral; Alcohol Deterrents; Alcohol Drinking; Animals; Animals, Outbred Strains; Baclofen; Behavior, Animal; Drug Synergism; Drug Therapy, Combination; GABA-B Receptor Agonists; Loperamide; Male; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Receptors, Opioid, mu	2012
Management of postoperative ileus. Orthopedics, 2012, Volume: 35, Issue:3 Topics: Combined Modality Therapy; Exercise Therapy; Gastrointestinal Agents; Humans; Ileus; Naltrexone; Narcotic Antagonists; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds	2012
Endogenous opioid and cannabinoid mechanisms are involved in the analgesic effects of celecoxib in the central nervous system. Pharmacology, 2012, Volume: 89, Issue:3-4 Topics: Analgesics; Animals; Carrageenan; Celecoxib; Central Nervous System; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Inflammation; Male; Naltrexone; Pain; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfonamides	2012
Structure of the human κ-opioid receptor in complex with JDTic. Nature, 2012, Mar-21, Volume: 485, Issue:7398 Topics: Binding Sites; Crystallography, X-Ray; Diterpenes, Clerodane; Guanidines; Humans; Models, Molecular; Morphinans; Mutagenesis, Site-Directed; Naltrexone; Piperidines; Protein Conformation; Receptors, Adrenergic, beta-2; Receptors, CXCR4; Receptors, Opioid, kappa; Structure-Activity Relationship; Tetrahydroisoquinolines	2012
Structural biology: How opioid drugs bind to receptors. Nature, 2012, May-16, Volume: 485, Issue:7398 Topics: Animals; Biomimetic Materials; Humans; Morphinans; Naltrexone; Nociceptin Receptor; Opioid Peptides; Piperidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spiro Compounds; Tetrahydroisoquinolines	2012
Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity. BMC pharmacology, 2012, May-29, Volume: 12 Topics: Animals; Biological Transport; Brain; Guanidines; Hydrophobic and Hydrophilic Interactions; Injections, Intraperitoneal; LLC-PK1 Cells; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Permeability; Piperidines; Receptors, Opioid, kappa; Swine; Tetrahydroisoquinolines	2012
Novel object recognition as a facile behavior test for evaluating drug effects in AβPP/PS1 Alzheimer's disease mouse model. Journal of Alzheimer's disease : JAD, 2012, Volume: 31, Issue:4 Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Donepezil; Drug Evaluation, Preclinical; Female; Humans; Indans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naltrexone; Pattern Recognition, Visual; Piperidines; Presenilin-1; Random Allocation	2012
The monoamine stabilizer (-)-OSU6162 attenuates voluntary ethanol intake and ethanol-induced dopamine output in nucleus accumbens. Biological psychiatry, 2012, Nov-15, Volume: 72, Issue:10 Topics: Alcohol Drinking; Animals; Behavioral Symptoms; Cues; Disease Models, Animal; Dopamine; Drug Discovery; Ethanol; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Piperidines; Rats; Reward; Secondary Prevention; Substance Withdrawal Syndrome	2012
Antinociceptive action of isolated mitragynine from Mitragyna Speciosa through activation of opioid receptor system. International journal of molecular sciences, 2012, Volume: 13, Issue:9 Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Male; Mice; Mice, Inbred ICR; Mitragyna; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Opioid; Secologanin Tryptamine Alkaloids	2012
The in vivo pharmacodynamics of the novel opioid receptor antagonist, TD-1211, in models of opioid-induced gastrointestinal and CNS activity. Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:6 Topics: Administration, Oral; Analgesics, Opioid; Animals; Benzamides; Central Nervous System; Dogs; Female; Gastrointestinal Tract; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pain; Piperidines; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tropanes	2013
The in vitro pharmacological profile of TD-1211, a neutral opioid receptor antagonist. Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:6 Topics: Animals; Benzamides; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Humans; In Vitro Techniques; Male; Mesocricetus; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tropanes	2013
Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. PloS one, 2013, Volume: 8, Issue:8 Topics: Allosteric Regulation; Biological Transport; Caco-2 Cells; Calcium; Guanidines; Humans; Kinetics; Morphinans; Naltrexone; Narcotic Antagonists; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Protein Binding; Receptors, Adrenergic, alpha; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrahydroisoquinolines	2013
Characterization of BU09059: a novel potent selective κ-receptor antagonist. ACS chemical neuroscience, 2014, Mar-19, Volume: 5, Issue:3 Topics: Animals; Cell Line, Tumor; CHO Cells; Cricetulus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Guanidines; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Isoquinolines; Male; Mice; Mice, Inbred Strains; Molecular Structure; Morphinans; Naltrexone; Narcotic Antagonists; Nociception; Piperidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrahydroisoquinolines; Vas Deferens	2014
Off-label uses of alvimopan and methylnaltrexone. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, Sep-01, Volume: 71, Issue:17 Topics: Analgesics, Opioid; Constipation; Gastrointestinal Agents; Humans; Ileus; Naltrexone; Narcotic Antagonists; Off-Label Use; Piperidines; Postoperative Complications; Quaternary Ammonium Compounds	2014
Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats. European journal of pharmacology, 2014, Dec-15, Volume: 745 Topics: Animals; Azabicyclo Compounds; Benzimidazoles; Dose-Response Relationship, Drug; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu; Reinforcement, Psychology; Remifentanil; Self Administration; Substance-Related Disorders	2014
Inhibition of DOR prevents remifentanil induced postoperative hyperalgesia through regulating the trafficking and function of spinal NMDA receptors in vivo and in vitro. Brain research bulletin, 2015, Volume: 110 Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Hot Temperature; Hyperalgesia; Lumbar Vertebrae; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Pain, Postoperative; Piperidines; Posterior Horn Cells; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Remifentanil; Spinal Cord; Tissue Culture Techniques; Touch	2015
Characterization of the Discriminative Stimulus Effects of a NOP Receptor Agonist Ro 64-6198 in Rhesus Monkeys. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:1 Topics: Analgesics, Opioid; Animals; Benzimidazoles; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Fentanyl; GABA Modulators; Imidazoles; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Pain Measurement; Piperidines; Receptors, Opioid; Spiro Compounds	2016
Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:11 Topics: Analgesics, Opioid; Anesthetics; Animals; Brain; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine; Extinction, Psychological; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Remifentanil; Self Administration; Time Factors	2016
Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption. Addiction biology, 2018, Volume: 23, Issue:2 Topics: Animals; Behavior, Animal; Buprenorphine; Cocaine; Conditioning, Operant; Cycloheptanes; Dopamine Uptake Inhibitors; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Piperidines; Rats; Receptors, Opioid; Receptors, Opioid, mu; Self Administration	2018
Choice between delayed food and immediate opioids in rats: treatment effects and individual differences. Psychopharmacology, 2017, Volume: 234, Issue:22 Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Choice Behavior; Conditioning, Operant; Delay Discounting; Dose-Response Relationship, Drug; Feeding Behavior; Individuality; Injections, Intravenous; Male; Naltrexone; Oxycodone; Piperidines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Remifentanil; Reward; Self Administration; Time Factors	2017
Profiling molecular factors associated with pyknosis and developmental arrest induced by an opioid receptor antagonist and dihydroartemisinin in Plasmodium falciparum. PloS one, 2017, Volume: 12, Issue:9 Topics: Antimalarials; Artemisinins; Benzylidene Compounds; Camphanes; Cannabinoid Receptor Antagonists; Cell Death; Chromatin; Dose-Response Relationship, Drug; Gene Expression Profiling; Glutathione; Naltrexone; Narcotic Antagonists; Oxidation-Reduction; Piperidines; Plasmodium falciparum; Pyrazoles; Rimonabant; Transcriptome	2017
A behavioral and pharmacological characterization of palatable diet alternation in mice. Pharmacology, biochemistry, and behavior, 2017, Volume: 163 Topics: Animals; Body Weight; Diet; Energy Intake; Feeding Behavior; Male; Mice; Mice, Inbred C57BL; Naltrexone; Piperazines; Piperidines; Pyrazoles; Rimonabant; Taste	2017
Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and cannabinoids. Epilepsy & behavior : E&B, 2018, Volume: 87 Topics: Analgesics, Opioid; Animals; Cannabinoid Receptor Antagonists; Convulsants; Disease Models, Animal; Electroshock; Male; Mice; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Piperidines; Pyrazoles; Receptors, Cannabinoid; Seizures; Stress, Psychological	2018
The selective κ-opioid receptor antagonist JDTic attenuates the alcohol deprivation effect in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019, Volume: 29, Issue:12 Topics: Alcohol Abstinence; Alcohol Deterrents; Alcohol Drinking; Animals; Ethanol; Male; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Self Administration; Tetrahydroisoquinolines	2019
A low pKa ligand inhibits cancer-associated pain in mice by activating peripheral mu-opioid receptors. Scientific reports, 2020, 10-29, Volume: 10, Issue:1 Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cancer Pain; Cell Line, Tumor; Fentanyl; Hydrogen-Ion Concentration; Hyperalgesia; Ligands; Male; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Receptors, Opioid, mu	2020
Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Docking. Molecules (Basel, Switzerland), 2021, 05-28, Volume: 26, Issue:11 Topics: Acute Pain; Analgesics; Animals; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Cycloheptanes; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Mice; Models, Molecular; Molecular Docking Simulation; Morphine; Movement; Naloxone; Naltrexone; Nociceptin; Oligopeptides; Opioid Peptides; Pain Management; Piperidines; Receptors, Opioid, mu	2021
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K Toxicology and applied pharmacology, 2022, 11-01, Volume: 454 Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Glyburide; Mice; Models, Theoretical; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Pentylenetetrazole; Piperidines; Potassium Channel Blockers; Potassium Channels; Pyridines; Receptors, Opioid; Seizures; Stroke; Sumatriptan; Tumor Necrosis Factor-alpha	2022