naltrexone and pentobarbital

naltrexone has been researched along with pentobarbital in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199021 (61.76)18.7374
1990's8 (23.53)18.2507
2000's3 (8.82)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carino, MA; Horita, A1
Bhargava, HN1
Gilbert, PE; Martin, WR1
Tang, RR; Tseng, LF1
Riley, AL; Smurthwaite, ST1
Inman, JG; Moss, IR; Segal, BS1
Grau, JW; King, RA; Meagher, MW1
Carino, MA; Chinn, C; Horita, A2
Bostwick, M; Martin, WR; Sloan, JW1
Brase, DA; Dewey, WL; Han, YH; Lux, F1
Hamada, T; Kameyama, T; Nakayama, S; Ukai, M1
Pechnick, RN; Terman, GW1
Liebeskind, JC; Pechnick, RN; Terman, GW1
Maier, SF1
Grau, JW1
Chapman, RW; Mauser, PJ1
Banks, WA; Galina, ZH; Haynes, HS; Johnson, BG; Kastin, AJ; Trentman, TL1
Fatherazi, S; Horita, A; Kazi, S; Lai, H1
Gintautas, JG; Kraynack, BJ1
Cannon, JT; Lewis, JW; Liebeskind, JC; Shavit, Y; Terman, GW1
Carino, MA; Horita, A; Yamawaki, S1
Herling, S; Solomon, RE; Woods, JH1
Shuster, L; Thompson, ML; Weiss, J1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH1
Collins, KA; Portoghese, PS; Tsai, JH; Tseng, LF1
Gewiss, MV; Goldberg, SR; Marley, RJ; Schindler, CW; Thorndike, EB1
Haile, CN; Jatlow, P; Kosten, TA1
Ali, JA; Rush, CR1
Endoh, T; Izumimoto, N; Kamei, J; Mizoguchi, H; Nagase, H; Narita, M; Saitoh, A; Suzuki, T; Tajima, A; Tseng, LF1
Dan, FJ; Hu, DY; Liu, LM; Lu, RQ; Pan, XK1

Reviews

1 review(s) available for naltrexone and pentobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for naltrexone and pentobarbital

ArticleYear
Naltrexone does not attenuate the acute behavioral effects of ethanol or pentobarbital in humans.
    Behavioural pharmacology, 1999, Volume: 10, Issue:4

    Topics: Adult; Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Double-Blind Method; Drug Interactions; Ethanol; Female; Humans; Hypnotics and Sedatives; Male; Memory; Naltrexone; Narcotic Antagonists; Pentobarbital; Psychomotor Performance; Sleep Stages; Surveys and Questionnaires

1999

Other Studies

32 other study(ies) available for naltrexone and pentobarbital

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Analeptic and antianaleptic effects of naloxone and naltrexone in rabbits.
    Life sciences, 1978, Oct-23, Volume: 23, Issue:16

    Topics: Amphetamine; Anesthesia; Animals; Central Nervous System Stimulants; Male; Motor Activity; Naloxone; Naltrexone; Pentobarbital; Rabbits; Reflex; Thyrotropin-Releasing Hormone; Time Factors

1978
Studies of the possible role of brain endorphins in pentobarbital anesthesia and toxicity in mice.
    Anesthesiology, 1979, Volume: 51, Issue:5

    Topics: Animals; Brain; Endorphins; Enkephalins; Leucine; Male; Mice; Morphine; Naloxone; Naltrexone; Pentobarbital; Phenylalanine

1979
Antagonism of the effects of pentobarbital in the chronic spinal dog by naltrexone.
    Life sciences, 1977, Apr-15, Volume: 20, Issue:8

    Topics: Animals; Body Temperature; Consciousness; Dogs; Heart Rate; Naloxone; Naltrexone; Pentobarbital; Reflex; Spinal Cord

1977
Pentobarbital attenuates antinociception induced by i.c.v. morphine but not beta-endorphin in the mouse.
    European journal of pharmacology, 1992, Apr-22, Volume: 214, Issue:2-3

    Topics: Animals; beta-Endorphin; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Narcotic Antagonists; Nociceptors; Pentobarbital; Receptors, Opioid

1992
Diprenorphine as a stimulus in drug discrimination learning.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:3

    Topics: Animals; Chlorides; Conditioning, Psychological; Diprenorphine; Discrimination Learning; Dose-Response Relationship, Drug; Female; Generalization, Psychological; Lithium; Lithium Chloride; Morphine; Nalorphine; Naloxone; Naltrexone; Pentobarbital; Rats

1992
Occlusion pressure response to inspiratory flow-resistive loading in anesthetized swine.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:5

    Topics: Airway Resistance; Anesthesia; Animals; Female; Male; Naltrexone; Pentobarbital; Pressure; Respiratory Mechanics; Swine; Swine, Miniature

1991
Role of supraspinal systems in environmentally induced antinociception: effect of spinalization and decerebration on brief shock-induced and long shock-induced antinociception.
    Behavioral neuroscience, 1990, Volume: 104, Issue:2

    Topics: Afferent Pathways; Animals; Arousal; Brain; Brain Mapping; Brain Stem; Cerebral Cortex; Electroshock; Male; Mesencephalon; Naltrexone; Neural Inhibition; Nociceptors; Pentobarbital; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Social Environment; Spinal Cord

1990
Fentanyl produces cholinergically-mediated analeptic and EEG arousal effects in rats.
    Neuropharmacology, 1989, Volume: 28, Issue:5

    Topics: Anesthesia; Animals; Atropine; Brain; Central Nervous System Stimulants; Choline; Electroencephalography; Fentanyl; Hippocampus; Injections; Male; Naltrexone; Parasympathetic Nervous System; Pentobarbital; Rats; Rats, Inbred Strains; Sleep; Stimulation, Chemical

1989
Mechanisms involved in the respiratory depressant actions of nicotine in anesthetized rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3

    Topics: Anesthesia; Animals; Female; Hexamethonium; Hexamethonium Compounds; Mecamylamine; Naltrexone; Nicotine; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Receptors, Opioid; Respiration; Urethane

1989
Studies on the mechanism of hypoglycemia induced by intrathecal morphine: dissociation from behavioral effects, effects of tolerance and depletion of liver glycogen.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3

    Topics: Animals; Behavior, Animal; Drug Interactions; Drug Tolerance; Female; Hypoglycemia; Injections, Spinal; Liver; Liver Glycogen; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Pentobarbital; Rats; Rats, Inbred Strains; Species Specificity; Strychnine

1989
Discriminative stimulus properties of the mixed agonist-antagonist pentazocine in the rat using two-choice discrete-trial avoidance paradigm.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2

    Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Rats; Rats, Inbred Strains

1989
The role of opiate receptors in the potentiation of pentobarbital sleeping time by the acute and chronic administration of opiates.
    Neuropharmacology, 1987, Volume: 26, Issue:11

    Topics: Animals; Dextrorphan; Drug Synergism; Levorphanol; Male; Naltrexone; Narcotics; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Opioid; Sleep; Stereoisomerism; Time Factors

1987
Potentiation of pentobarbital sleeping time by the acute and chronic administration of morphine.
    NIDA research monograph, 1987, Volume: 76

    Topics: Animals; Drug Synergism; Male; Morphine; Naltrexone; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Opioid; Sleep

1987
Codeine produces a cholinergically mediated analeptic effect in rats and rabbits.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1

    Topics: Animals; Brain; Central Nervous System Stimulants; Choline; Codeine; Diazepam; Drug Interactions; Male; Naltrexone; Pentobarbital; Rabbits; Rats; Rats, Inbred Strains; Synaptosomes

1988
Determinants of the nature of environmentally induced hypoalgesia.
    Behavioral neuroscience, 1989, Volume: 103, Issue:1

    Topics: Analgesia; Animals; Electroshock; Endorphins; Male; Naltrexone; Pain; Pentobarbital; Rats; Rats, Inbred Strains; Stress, Psychological

1989
The central representation of an aversive event maintains the opioid and nonopioid forms of analgesia.
    Behavioral neuroscience, 1987, Volume: 101, Issue:2

    Topics: Animals; Arousal; Attention; Avoidance Learning; Brain; Male; Mental Recall; Naltrexone; Neural Inhibition; Nociceptors; Pentobarbital; Rats; Receptors, Opioid; Spinal Cord; Synaptic Transmission

1987
Role of endogenous opioids on ventilation and chemical control of breathing in pentobarbitone-anesthetized rats.
    Pharmacology, 1987, Volume: 35, Issue:6

    Topics: Anesthesia; Animals; Blood Gas Analysis; Carbon Dioxide; Endorphins; Hydrogen-Ion Concentration; Hypoxia; Injections, Intraventricular; Male; Naloxone; Naltrexone; Pentobarbital; Rats; Respiration; Respiratory Function Tests

1987
Mediation of serotonin-induced analgesia by the 5HT2 receptor in the pentobarbital anesthetized mouse model.
    Brain research bulletin, 1988, Volume: 21, Issue:6

    Topics: Analgesics; Anesthesia; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Naltrexone; Pentobarbital; Receptors, Serotonin; Serotonin; Time Factors

1988
Intraseptal morphine potentiates pentobarbital narcosis and hypothermia in the rat.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:4

    Topics: Anesthesia; Animals; Body Temperature; Cerebral Cortex; Drug Synergism; Injections; Male; Morphine; Naltrexone; Pentobarbital; Rats; Rats, Inbred Strains; Sleep; Time Factors

1985
Naloxone: analeptic action unrelated to opiate receptor antagonism?
    Anesthesiology, 1982, Volume: 56, Issue:4

    Topics: Animals; Central Nervous System Stimulants; Halothane; Injections, Intraventricular; Ketamine; Male; Naloxone; Naltrexone; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Opioid; Sleep

1982
Intrinsic mechanisms of pain inhibition: activation by stress.
    Science (New York, N.Y.), 1984, Dec-14, Volume: 226, Issue:4680

    Topics: Adaptation, Physiological; Adrenalectomy; Anesthesia; Animals; Brain Stem; Conditioning, Psychological; Electroshock; Endorphins; Histamine; Humans; Hypophysectomy; Immunosuppression Therapy; Naltrexone; Neoplasms; Nociceptors; Pain; Pentobarbital; Rats; Stress, Physiological

1984
Morphine antagonizes pentobarbital-induced anesthesia.
    Neuropharmacology, 1983, Volume: 22, Issue:10

    Topics: Anesthesia; Animals; Atropine; Behavior, Animal; Electroencephalography; Male; Morphine; Naloxone; Naltrexone; Pentobarbital; Rabbits; Seizures

1983
Discriminative stimulus effects of dextrorphan in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3

    Topics: Animals; Bemegride; Binding Sites; Columbidae; Dextrorphan; Dioxolanes; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Generalization, Stimulus; Morphinans; Naltrexone; Pentobarbital; Piperidines; Stereoisomerism; Structure-Activity Relationship

1983
Effects of naloxone and naltrexone on drug-induced hypothermia in mice.
    Neuropharmacology, 1984, Volume: 23, Issue:5

    Topics: Animals; Apomorphine; Body Temperature; Body Temperature Regulation; Dopamine; Haloperidol; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotics; Pentobarbital

1984
Narcotic discrimination in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity

1980
Spinal delta 2-, but not delta 1-, mu-, or kappa-opioid receptors are involved in the tail-flick inhibition induced by beta-endorphin from nucleus raphe obscurus in the pentobarbital-anesthetized rat.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Amino Acid Sequence; Analgesia; Animals; Benzylidene Compounds; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pentobarbital; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail

1995
GABA receptor-linked chloride channels and the behavioral effects of naltrexone in rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3

    Topics: Animals; Behavior, Animal; Chloride Channels; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Ion Channel Gating; Male; Naltrexone; Pentobarbital; Picrotoxin; Rats; Receptors, GABA; Reinforcement Schedule

1994
Naltrexone and morphine alter the discrimination and plasma levels of ethanol.
    Behavioural pharmacology, 1999, Volume: 10, Issue:1

    Topics: Animals; Central Nervous System Depressants; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Hypnotics and Sedatives; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pentobarbital; Rats; Rats, Inbred Lew

1999
TRK-820, a selective kappa-opioid agonist, produces potent antinociception in cynomolgus monkeys.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Macaca fascicularis; Morphinans; Morphine; Naloxone; Naltrexone; Pain Measurement; Pentazocine; Pentobarbital; Receptors, Opioid, kappa; Spiro Compounds

2001
Subclass opioid receptors associated with the cardiovascular depression after traumatic shock and the antishock effects of its specific receptor antagonists.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:5

    Topics: Animals; Blood Pressure; Cardiovascular System; Enkephalin, Leucine; Femur; Free Radicals; GABA Modulators; Hemodynamics; Models, Statistical; Naltrexone; Narcotic Antagonists; Pentobarbital; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Shock; Time Factors

2005