naltrexone has been researched along with nociceptin in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (35.48) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Kavaliers, M; Perrot-Sinal, TS | 1 |
| Butour, JL; Meunier, JC; Moisand, C; Mollereau, C; Parmentier, M | 1 |
| Cai, YC; Cheng, ZJ; Fan, GH; Jiang, LZ; Ma, L; Pei, G | 1 |
| Giuliani, S; Maggi, CA | 1 |
| Childers, SR; Sim, LJ | 1 |
| Bodnar, RJ; Leventhal, L; Mathis, JP; Pasternak, GW; Rossi, GC | 1 |
| Corbett, AD; McKnight, AT; Menzies, JR; Nicholson, JR; Paterson, SJ | 1 |
| Xie, CW; Yu, TP | 1 |
| Hao, S; Ogawa, H | 1 |
| Chu, XP; Li, P; Wang, JQ; Xu, NS | 1 |
| Dun, NJ; Hwang, BH; Mizoguchi, H; Nagase, H; Narita, M; Oji, DE; Tseng, LF | 1 |
| Hiramatsu, M; Inoue, K | 1 |
| Freeman, FM; Young, IG | 1 |
| Altememi, GF; Mandyam, CD; Standifer, KM | 1 |
| Lutfy, K; Maidment, NT | 1 |
| Gabriel, A; Grond, S; Huang, YH; Lu, JT; Meuser, T; Pierce Palmer, P; Pietruck, C; Yu, LC | 1 |
| Bastia, E; Bertorelli, R; Citterio, F; Corradini, L; Forlani, A; Ongini, E | 1 |
| Armstead, WM; Kulkarni, M | 1 |
| Ciccocioppo, R; Economidou, D; Heilig, M; Massi, M; Rimondini, R; Sommer, W | 1 |
| Egli, M; Heilig, M | 1 |
| Kennedy, RT; Ko, MC; Wei, H; Woods, JH | 1 |
| Auerbach, SB; Ma, Z; McCarley, RW; Tao, R; Thakkar, MM | 1 |
| Martin, KK; Stahlheber, BW; Stevens, CW | 1 |
| Gyires, K; Zádori, Z | 1 |
| Calò, G; Guerrini, R; Hu, E; Ko, MC | 1 |
| Lee, H | 1 |
| Ciccocioppo, R; Economidou, D; Heilig, M; Kinoshita, H; Kuriyama, M; Roberto, M; Stopponi, S; Teshima, K; Weiss, F | 1 |
| Burke, NN; Deaver, DR; Ferdousi, M; Finn, DP; Kelly, JP; Roche, M | 1 |
| Ballet, S; Bermudez, M; De Neve, J; Dumitrascuta, M; Spetea, M; Trovato, O; Wolber, G | 1 |
| Cami-Kobeci, G; Cippitelli, A; Husbands, SM; Martinez, M; Toll, L; Zribi, G | 1 |
| Billeci, D; Candeletti, S; Coluzzi, F; Losapio, LM; Rocco, M; Romualdi, P; Rullo, L; Scerpa, MS | 1 |
2 review(s) available for naltrexone and nociceptin
| Article | Year |
|---|---|
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Animals; Baclofen; Corticotropin-Releasing Hormone; Disease Models, Animal; Disulfiram; Fructose; Humans; Naltrexone; Neuropeptide Y; Nociceptin; Ondansetron; Opioid Peptides; Receptor, Cannabinoid, CB1; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Taurine; Topiramate | 2006 |
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation.
Topics: Analgesics, Opioid; Animals; Buprenorphine; Drug Tolerance; Humans; Isoquinolines; Naltrexone; Nociceptin; Opioid Peptides; Pain; Phenylpropionates; Receptors, Opioid, mu | 2022 |
29 other study(ies) available for naltrexone and nociceptin
| Article | Year |
|---|---|
Pronociceptive effects of the neuropeptide, nociceptin, in the land snail, Cepaea nemoralis.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Dynorphins; Hot Temperature; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptors; Opioid Peptides; Pain Measurement; Receptors, Opioid; Receptors, Opioid, kappa; Snails; Time Factors | 1996 |
Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Diprenorphine; Dynorphins; Etorphine; Fentanyl; Glutamine; Histamine; Humans; Kinetics; Ligands; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid | 1996 |
Functional expression, activation and desensitization of opioid receptor-like receptor ORL1 in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; GTP-Binding Proteins; Hybrid Cells; Naltrexone; Narcotic Antagonists; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pertussis Toxin; Receptors, Opioid; Receptors, Opioid, delta; Virulence Factors, Bordetella | 1997 |
Prejunctional modulation by nociceptin of nerve-mediated inotropic responses in guinea-pig left atrium.
Topics: Animals; Atrial Function; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Naloxone; Naltrexone; Neuromuscular Junction; Neurons, Afferent; Nociceptin; Opioid Peptides; Sensory Receptor Cells | 1997 |
Anatomical distribution of mu, delta, and kappa opioid- and nociceptin/orphanin FQ-stimulated [35S]guanylyl-5'-O-(gamma-thio)-triphosphate binding in guinea pig brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Autoradiography; Brain Chemistry; Cerebellum; Diencephalon; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Medulla Oblongata; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pons; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Telencephalon | 1997 |
Orphan opioid receptor antisense probes block orphanin FQ-induced hyperphagia.
Topics: Animals; Eating; Exons; Hyperphagia; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Oligonucleotides, Antisense; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1998 |
Pharmacological studies on the "orphan" opioid receptor in central and peripheral sites.
Topics: Animals; beta-Endorphin; Binding Sites; Brain; Cell Membrane; Choline; Guinea Pigs; Male; Myenteric Plexus; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rabbits; Radioligand Assay; Rats; Receptors, Opioid; Vas Deferens | 1998 |
Orphanin FQ/nociceptin inhibits synaptic transmission and long-term potentiation in rat dentate gyrus through postsynaptic mechanisms.
Topics: Action Potentials; Animals; Dentate Gyrus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; N-Methylaspartate; Naloxone; Naltrexone; Narcotic Antagonists; Neural Inhibition; Nociceptin; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Synapses; Synaptic Transmission; Tetrodotoxin | 1998 |
Naltrexone, but not atropine or yohimbine, antagonizes suppression of formalin-induced spinal sensitization by intrathecal nociceptin.
Topics: Animals; Atropine; Depression, Chemical; Formaldehyde; Injections, Spinal; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptors; Opioid Peptides; Pain Measurement; Parasympatholytics; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spine; Sympatholytics; Yohimbine | 1998 |
Endomorphin-1 and endomorphin-2, endogenous ligands for the mu-opioid receptor, inhibit electrical activity of rat rostral ventrolateral medulla neurons in vitro.
Topics: Animals; Electrophysiology; Enkephalin, Methionine; In Vitro Techniques; Ligands; Male; Medulla Oblongata; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Nociceptin; Oligopeptides; Opioid Peptides; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1999 |
Identification of the G-protein-coupled ORL1 receptor in the mouse spinal cord by [35S]-GTPgammaS binding and immunohistochemistry.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Autoradiography; Baclofen; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Haloperidol; Immunohistochemistry; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Propranolol; Receptors, Opioid; Somatostatin; Spinal Cord; Sulfur Radioisotopes; Yohimbine | 1999 |
Improvement by low doses of nociceptin on scopolamine-induced impairment of learning and/or memory.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Disease Models, Animal; Dizocilpine Maleate; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Nociceptin; Opioid Peptides; Psychomotor Performance; Rats; Scopolamine | 2000 |
Identification of the opioid receptors involved in passive-avoidance learning in the day-old chick during the second wave of neuronal activity.
Topics: Age Factors; Amnesia; Analgesics, Opioid; Animals; Anisomycin; Avoidance Learning; Brain Chemistry; Chickens; Chloramphenicol; Conditioning, Psychological; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Female; Male; Memory; Naltrexone; Narcotic Antagonists; Neurons; Nociceptin; Oligopeptides; Opioid Peptides; Protein Synthesis Inhibitors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vasodilator Agents | 2000 |
beta-Funaltrexamine inactivates ORL1 receptors in BE(2)-C human neuroblastoma cells.
Topics: Brain Neoplasms; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Neuroblastoma; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, mu; Tumor Cells, Cultured | 2000 |
Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, mu; Somatostatin | 2000 |
Involvement of endogenous opioid systems in nociceptin-induced spinal antinociception in rats.
Topics: Animals; Endorphins; Hindlimb; Hot Temperature; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptors; Opioid Peptides; Pain; Pain Measurement; Peptide Fragments; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord | 2002 |
Lack of the nociceptin receptor does not affect acute or chronic nociception in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Male; Mice; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Pain; Receptors, Opioid; Time Factors; Vas Deferens | 2002 |
Relationship between NOC/oFQ, dynorphin, and COX-2 activation in impaired NMDA cerebrovasodilation after brain injury.
Topics: Animals; Animals, Newborn; Brain Injuries; Cyclooxygenase 2; Dynorphins; Enzyme Activation; Female; Glutamic Acid; Indomethacin; Isoenzymes; Male; N-Methylaspartate; Naltrexone; Nitrobenzenes; Nociceptin; Opioid Peptides; Pia Mater; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Superoxides; Swine; Vasodilation | 2002 |
Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Behavior, Animal; Buprenorphine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Administration Routes; Drug Interactions; Eating; Ethanol; Exploratory Behavior; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Receptors, Opioid; Receptors, Opioid, mu; Time Factors | 2007 |
Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies.
Topics: Analgesics; Animals; Behavior, Animal; Female; Injections, Spinal; Macaca mulatta; Male; Mass Spectrometry; Naltrexone; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spinal Cord | 2006 |
Nociceptin/orphanin FQ decreases serotonin efflux in the rat brain but in contrast to a kappa-opioid has no antagonistic effect on mu-opioid-induced increases in serotonin efflux.
Topics: Animals; Dose-Response Relationship, Drug; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Nociceptin; Nucleus Accumbens; Opioid Peptides; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin | 2007 |
Nociceptin produces antinociception after spinal administration in amphibians.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Injections, Spinal; Naltrexone; Nociceptin; Opioid Peptides; Pain Threshold; Peptide Fragments; Rana pipiens | 2009 |
[Analysis of central mechanisms involved in gastric mucosal integrity].
Topics: Animals; Arachidonic Acids; beta-Endorphin; Clonidine; Endocannabinoids; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; Excitatory Amino Acids; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nociceptin; Oligopeptides; Opioid Peptides; Oxazoles; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Opioid; Rilmenidine; Stomach Ulcer | 2008 |
Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112.
Topics: Analgesics; Animals; Benzimidazoles; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Macaca mulatta; Male; Morphine; Naltrexone; Nociceptin; Opioid Peptides; Pain Measurement; Pain Threshold; Piperidines | 2010 |
Effects of co-administration of intrathecal nociceptin/orphanin FQ and opioid antagonists on formalin-induced pain in rats.
Topics: Analgesics; Animals; Formaldehyde; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 2013 |
Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat.
Topics: Acenaphthenes; Alcohol Deterrents; Alcohol Drinking; Animals; Benzimidazoles; Choice Behavior; Dose-Response Relationship, Drug; Drug-Seeking Behavior; HEK293 Cells; Humans; Male; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid; Stress, Psychological; Substance Withdrawal Syndrome | 2014 |
Locomotor and anti-immobility effects of buprenorphine in combination with the opioid receptor modulator samidorphan in rats.
Topics: Amygdala; Animals; Behavior, Animal; Buprenorphine; Depression; Hippocampus; Male; Motor Activity; Naltrexone; Nociceptin; Opioid Peptides; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; RNA, Messenger; Swimming | 2019 |
Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Docking.
Topics: Acute Pain; Analgesics; Animals; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Cycloheptanes; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Mice; Models, Molecular; Molecular Docking Simulation; Morphine; Movement; Naloxone; Naltrexone; Nociceptin; Oligopeptides; Opioid Peptides; Pain Management; Piperidines; Receptors, Opioid, mu | 2021 |
PPL-138 (BU10038): A bifunctional NOP/mu partial agonist that reduces cocaine self-administration in rats.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Isoquinolines; Male; Naltrexone; Nociceptin; Opioid Peptides; Phenylpropionates; Rats; Receptors, Opioid; Receptors, Opioid, mu; Self Administration | 2022 |