naltrexone has been researched along with naltrindole benzofuran in 96 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 49 (51.04) | 18.2507 |
2000's | 30 (31.25) | 29.6817 |
2010's | 14 (14.58) | 24.3611 |
2020's | 3 (3.13) | 2.80 |
Authors | Studies |
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Portoghese, PS | 1 |
Lin, CE; MaloneyHuss, KE; Nagase, H; Portoghese, PS; Takemori, AE | 1 |
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
Strassburg, CP; Tukey, RH | 1 |
Fujii, H; Kobayashi, S; Miyata, Y; Nagase, H; Osa, Y; Takeuchi, T | 1 |
Iwata, S; Koyama, Y; Kutsumura, N; Miyata, Y; Nagase, H; Nagumo, Y; Nakajima, R; Saitoh, T; Yamamoto, N; Yoshida, N | 1 |
Nagase, H; Portoghese, PS; Sultana, M; Takemori, AE | 1 |
Portoghese, PS; Sofuoglu, M; Takemori, AE | 2 |
Freye, E; Latasch, L; Portoghese, PS | 1 |
Collins, KA; Portoghese, PS; Tsai, JH; Tseng, LF | 1 |
Froehlich, JC; Krishnan-Sarin, S; Li, TK; Portoghese, PS | 1 |
Hammond, DL; Littell, L; Stewart, PE | 1 |
Fujimoto, JM; Holmes, BB; Killian, P; Portoghese, PS; Takemori, AE | 1 |
Bergsbaken, C; Law, PY | 1 |
Funada, M; Misawa, M; Mori, T; Nagase, H; Suzuki, T | 1 |
Kamei, J; Misawa, M; Mizoguchi, H; Nagase, H; Suzuki, T; Yoshiike, M | 1 |
Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T | 1 |
Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M | 2 |
Crook, TJ; Hill, RG; Kitchen, I; Muhammad, BY | 1 |
Hammond, DL; Holper, EM; Stewart, PE | 1 |
Fujimoto, JM; Portoghese, PS; Rady, JJ; Takemori, AE | 1 |
Hammond, DL; Stewart, PE | 2 |
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T | 1 |
Portoghese, PS; Takemori, AE | 2 |
Bowen, WD; Carlisi, VJ; Hruby, VJ; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE; Wild, KD | 1 |
Miyamoto, Y; Portoghese, PS; Takemori, AE | 2 |
Collins, KA; Portoghese, PS; Tseng, LF | 1 |
Bhargava, HN; House, RV; Kozak, JT; Thomas, PT | 1 |
Kinter, CM; Lever, JR; Scheffel, U; Stathis, M | 1 |
Funada, M; Schutz, CG; Shippenberg, TS | 1 |
Mizoguchi, H; Nagase, H; Narita, M; Quock, RM; Suzuki, T; Tseng, LF | 1 |
Bhargava, HN; House, RV; Thomas, PT; Zhao, GM | 1 |
Baemmert, D; Fujimoto, JM; Portoghese, PS; Rady, JJ; Takemori, AE | 1 |
Hitosugi, H; Kamei, J; Kashiwazaki, T; Nagase, H | 1 |
Dawson-Basoa, M; Gintzler, AR | 2 |
Donahue, BB; Hammond, DL; Stewart, PE | 1 |
Mizoguchi, H; Nagase, H; Narita, M; Tseng, LF | 1 |
Hammond, DL; Thorat, SN | 1 |
Gross, GJ; Hsu, AK; Schultz, JE | 1 |
Inturrisi, CE; Jenab, S; Kao, B; Kest, B; Lee, CE | 1 |
Lever, JR; Scheffel, U | 1 |
Fujimoto, JM; Gorny, JM; Rady, JJ | 1 |
Fields, HL; Hirakawa, N; Tershner, SA | 1 |
Froehlich, JC; June, HL; Li, TK; McCane, SR; Portoghese, PS; Zink, RW | 1 |
Kamei, J; Nagase, H; Ohsawa, M; Onodera, K; Taki, K | 1 |
Fields, HL; Harasawa, I; Meng, ID | 1 |
Helmstetter, FJ; Tershner, SA | 1 |
Carl, K; Garrett, KM; Holloway, FA; Mhatre, MC | 1 |
Cho, KP; Kim, KW; Shin, BS; Son, Y | 1 |
Hammond, DL; Hurley, RW | 1 |
Fujimoto, JM; Holmes, BB; Rady, JJ; Tseng, LF | 1 |
Filliol, D; Gavériaux-Ruff, C; Kieffer, BL; Matthes, HW; Simonin, F | 1 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE | 1 |
Adler, MW; Cowan, A; Eisenstein, TK; Gaughan, J; Geller, EB; Meissler, JJ; Rahim, RT; Rogers, TJ | 1 |
Berzetei-Gurske, IP; Harris, HE; Klareskog, L; Schmidhammer, H; Spetea, M | 1 |
Liu, JG; Prather, PL | 1 |
Broom, DC; Nitsche, JF; Pintar, JE; Rice, KC; Traynor, JR; Woods, JH | 1 |
Caffrey, JL; Farias, M; Jackson, KE; Yoshishige, D | 1 |
Lunzer, MM; Portoghese, PS | 2 |
Brown, DR; Townsend, DW | 1 |
Laurito, CE; Lu, Y; Sweitzer, SM; Yeomans, DC | 1 |
Abe, K; Shirasaki, T; Soeda, F; Takahama, K | 1 |
Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Suzuki, T; Takada, K | 1 |
Agadjanov, MI; Agadjanova, EM; Batikyan, TB; Tadevosyan, YV; Vartanian, GS | 1 |
Kamei, J; Onodera, K; Saitoh, A; Yoshikawa, Y | 1 |
Castro, MS; Duarte, ID; Francischi, JN; Pacheco, DF; Perez, AC; Reis, GM | 1 |
Banoub, J; Cecchelli, R; El Aneed, A; Joly, N; Martin, P | 1 |
Kamei, J; Miyata, S; Saitoh, A; Takahashi, M | 1 |
Fushiki, T; Inoue, K; Matsumura, S; Mizushige, T; Tsuzuki, S; Yoneda, T | 1 |
Dimitrijević, M; Kovacević-Jovanović, V; Kustrimović, N; Miletić, T; Mitić, K; Stanojević, S; Vujić, V | 1 |
Ito, S; Mori, T; Sawaguchi, T | 1 |
Asehnoune, K; Beloeil, H; Benhamou, D; Bonnet, MP; Mazoit, JX | 1 |
Chefer, VI; Shippenberg, TS; Thompson, AC | 1 |
Billa, SK; Morón, JA; Xia, Y | 1 |
Barzakh, EI; Chernysheva, GA; Cybulnikov, SY; Krieg, T; Krylatov, AV; Lishmanov, AY; Maslov, LN; Solenkova, NV; Zhang, Y | 1 |
Milan-Lobo, L; Whistler, JL | 1 |
Fujii, H; Nagase, H; Nemoto, T; Oka, J; Saitoh, A; Sugiyama, A; Wada, K; Yamada, M | 1 |
Nagase, H; Oka, J; Saitoh, A; Sugiyama, A; Yamada, M | 1 |
Chubanov, V; Gudermann, T; Hofmann, T; Linseisen, M; Schäfer, S; Sytik, L | 1 |
Beaudry, H; Gendron, L; Morón, JA | 1 |
Chubanov, V; Ferioli, S; Gudermann, T; Hofmann, T; Schäfer, S; Zierler, S | 1 |
Benz, N; Buscaglia, P; Calvez, ML; Férec, C; Horgen, FD; Huguet, F; Kerbiriou, M; Le Hir, S; Mignen, O; Trouvé, P | 1 |
Feng, ZP; Rutka, JT; Sun, HS; Turlova, E; Wong, R | 1 |
Kang, Y; Kim, JH; Lee, PR; Oh, SB; Vang, H; Won, J | 1 |
Inoue, H; Konishi, M; Tashiro, M | 1 |
Maslov, LN; Naryzhnaya, NV; Nesterov, EA; Prokudina, ES; Tsibulnikov, SY | 1 |
DenBesten, P; Földes, A; Juhász, V; Kádár, K; Kató, E; Köles, L; Löchli, H; Rácz, R; Steward, MC; Varga, G; Zhang, Y; Zsembery, Á | 1 |
Cao, JL; Chen, R; Ding, L; Fei, YH; Guo, F; Jiang, Y; Liu, N; Liu, Y; Lu, C; Qi, J; Sui, Z; Wang, MM; Wang, W; Wang, X; Wang, Y; Wei, X; Wu, M; Xing, Y; Zhang, P; Zhang, Y | 1 |
1 review(s) available for naltrexone and naltrindole benzofuran
Article | Year |
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Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
95 other study(ies) available for naltrexone and naltrindole benzofuran
Article | Year |
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An approach to the design of receptor-type-selective non-peptide antagonists of peptidergic receptors: delta opioid antagonists.
Topics: Amino Acid Sequence; Drug Design; Enkephalins; Indoles; Molecular Sequence Data; Morphinans; Naltrexone; Protein Conformation; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship | 1991 |
Role of spacer and address components in peptidomimetic delta opioid receptor antagonists related to naltrindole.
Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Indoles; Male; Mice; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship | 1991 |
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Opioid δ₁ receptor antagonist 7-benzylidenenaltrexone as an effective resistance reverser for chloroquine-resistant Plasmodium chabaudi.
Topics: Antimalarials; Benzylidene Compounds; Chloroquine; Drug Resistance; Molecular Structure; Naltrexone; Parasitic Sensitivity Tests; Plasmodium chabaudi; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2011 |
Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives.
Topics: Animals; Antitrichomonal Agents; Benzylidene Compounds; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Molecular Structure; Naltrexone; Receptors, Opioid, delta; Structure-Activity Relationship; Trichomonas vaginalis | 2017 |
Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone.
Topics: Animals; Indoles; Ligands; Male; Mice; Morphinans; Morpholines; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1992 |
delta-Opioid receptor binding in mouse brain: evidence for heterogeneous binding sites.
Topics: Animals; Binding, Competitive; Brain Chemistry; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Membranes; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta | 1992 |
The delta receptor is involved in sufentanil-induced respiratory depression--opioid subreceptors mediate different effects.
Topics: Animals; Carbon Dioxide; Dogs; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Indoles; Morphinans; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Nociceptors; Oxygen; Receptors, Opioid; Receptors, Opioid, delta; Respiration; Sufentanil | 1992 |
Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes.
Topics: Analgesia; Animals; Indoles; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta | 1991 |
Spinal delta 2-, but not delta 1-, mu-, or kappa-opioid receptors are involved in the tail-flick inhibition induced by beta-endorphin from nucleus raphe obscurus in the pentobarbital-anesthetized rat.
Topics: Amino Acid Sequence; Analgesia; Animals; Benzylidene Compounds; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pentobarbital; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1995 |
The delta 2-opioid receptor antagonist naltriben selectively attenuates alcohol intake in rats bred for alcohol preference.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Brain Chemistry; Male; Naltrexone; Quinine; Rats; Rats, Wistar; Receptors, Opioid, delta | 1995 |
Antinociception and delta-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1995 |
Cold water swim stress- and delta-2 opioid-induced analgesia are modulated by spinal gamma-aminobutyric acidA receptors.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naltrexone; Picrotoxin; Receptors, GABA-A; Receptors, Opioid, delta; Spinal Cord; Stress, Physiological; Swimming | 1995 |
Properties of delta opioid receptor in neuroblastoma NS20Y: receptor activation and neuroblastoma proliferation.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Division; Cyclic AMP; Humans; In Vitro Techniques; Mice; Naloxone; Naltrexone; Neuroblastoma; Pertussis Toxin; Receptors, Opioid, delta; Second Messenger Systems; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Attenuation of the discriminative stimulus properties of cocaine by delta-opioid receptor antagonists.
Topics: Animals; Benzylidene Compounds; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Naltrexone; Rats; Rats, Inbred F344; Receptors, Opioid, delta | 1994 |
Blockade of delta-opioid receptors prevents morphine-induced place preference in mice.
Topics: Analgesics; Animals; Benzylidene Compounds; Conditioning, Operant; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu | 1994 |
Involvement of delta-opioid receptors in the effects of morphine on locomotor activity and the mesolimbic dopaminergic system in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Dopamine; Homovanillic Acid; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Postural Balance; Reaction Time; Receptors, Opioid, delta | 1993 |
The role of delta-opioid receptor subtypes in cocaine- and methamphetamine-induced place preferences.
Topics: Animals; Benzylidene Compounds; Cocaine; Conditioning, Psychological; Male; Methamphetamine; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reinforcement, Psychology | 1994 |
Evidence that weaning stimulates the developmental expression of a delta-opioid receptor subtype in the rat.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Weaning | 1994 |
Delta antagonist and kappa agonist activity of Naltriben: evidence for differential kappa interaction with the delta 1 and delta 2 opioid receptor subtypes.
Topics: Animals; Male; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1994 |
Supraspinal delta receptor subtype activity of heroin and 6-monoacetylmorphine in Swiss Webster mice.
Topics: Animals; Benzylidene Compounds; Heroin; Male; Mice; Morphine Derivatives; Naltrexone; Pain; Receptors, Opioid, delta | 1994 |
Activation of spinal delta-1 or delta-2 opioid receptors reduces carrageenan-induced hyperalgesia in the rat.
Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Male; Naltrexone; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1994 |
Involvement of delta 1-opioid receptor antagonism in the antitussive effect of delta-opioid receptor antagonists.
Topics: Animals; Antitussive Agents; Benzylidene Compounds; Capsaicin; Cough; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta | 1994 |
Enkephalin antinociception in mice is mediated by delta 1- and delta 2-opioid receptors in the brain and spinal cord, respectively.
Topics: Animals; Benzylidene Compounds; beta-Endorphin; Brain; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naltrexone; Pain; Receptors, Opioid, delta; Spinal Cord | 1993 |
Evidence for a single functional opioid delta receptor subtype in the mouse isolated vas deferens.
Topics: Animals; Benzylidene Compounds; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Morphinans; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Thiocyanates; Vas Deferens | 1993 |
Involvement of delta 2 opioid receptors in the development of morphine dependence in mice.
Topics: Animals; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphinans; Morphine Dependence; Naloxone; Naltrexone; Receptors, Opioid, delta; Substance Withdrawal Syndrome; Thiocyanates | 1993 |
Spinal delta 2 but not delta 1 opioid receptors are involved in intracerebroventricular beta-endorphin-induced antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzylidene Compounds; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Pyrrolidines; Receptors, Opioid, delta; Spinal Cord | 1993 |
Involvement of delta 2 opioid receptors in acute dependence on morphine in mice.
Topics: Animals; Drug Interactions; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphine; Naltrexone; Receptors, Opioid, delta; Substance-Related Disorders; Thiocyanates | 1993 |
Evidence for delta opioid receptor subtypes in rat spinal cord: studies with intrathecal naltriben, cyclic[D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Reflex; Spinal Cord | 1993 |
The mixed antinociceptive agonist-antagonist activity of beta-endorphin(1-27) in mice.
Topics: Animals; Benzylidene Compounds; beta-Endorphin; Male; Mice; Naltrexone; Narcotic Antagonists; Nociceptors; Peptide Fragments; Receptors, Opioid | 1993 |
Suppression of immune function by non-peptidic delta opioid receptor antagonists.
Topics: Animals; B-Lymphocytes; Female; Immunosuppressive Agents; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Spleen; T-Lymphocytes, Helper-Inducer | 1995 |
In vivo labeling of delta opioid receptors in mouse brain by [3H]benzylidenenaltrexone, a ligand selective for the delta 1 subtype.
Topics: Animals; Benzylidene Compounds; Corpus Striatum; Male; Mice; Naltrexone; Radioligand Assay; Receptors, Opioid, delta; Tritium | 1996 |
Role of delta-opioid receptors in mediating the aversive stimulus effects of morphine withdrawal in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substance Withdrawal Syndrome | 1996 |
Use of antisense oligodeoxynucleotide to determine delta-opioid receptor involvement in [D-Ala2]deltorphin II-induced locomotor hyperactivity.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; Base Sequence; Benzylidene Compounds; Cerebral Ventricles; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Motor Activity; Naltrexone; Narcotic Antagonists; Oligonucleotides, Antisense; Oligopeptides; Receptors, Opioid, delta; Somatostatin; Thionucleotides | 1996 |
Effects of chronic administration of 7-benzylidene-7-dehydronaltrexone and naltriben on the antinociceptive actions of delta 1- and delta 2-opioid receptor agonists.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Enkephalins; Female; Membranes; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Receptors, Opioid; Receptors, Opioid, delta | 1996 |
Spinal delta opioid receptor subtype activity of 6-monoacetylmorphine in Swiss Webster mice.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; beta-Endorphin; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Spinal Cord | 1997 |
The role of spinal delta1-opioid receptors in inhibiting the formalin-induced nociceptive response in diabetic mice.
Topics: Analgesics; Animals; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Formaldehyde; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Spinal Cord | 1997 |
Involvement of spinal cord delta opiate receptors in the antinociception of gestation and its hormonal simulation.
Topics: Animals; Benzylidene Compounds; Female; Humans; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Pain; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Sensory Thresholds; Sex Characteristics; Spinal Cord; Time Factors | 1997 |
The role of delta-opioid receptors in the discriminative stimulus properties of a low dose of methamphetamine.
Topics: Animals; Benzylidene Compounds; Central Nervous System Stimulants; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Naltrexone; Quinolines; Rats; Rats, Inbred F344; Receptors, Opioid, delta | 1997 |
Role of spinal delta1 and delta2 opioid receptors in the antinociception produced by microinjection of L-glutamate in the ventromedial medulla of the rat.
Topics: Analgesics; Animals; Benzylidene Compounds; Glutamic Acid; Isothiocyanates; Male; Medulla Oblongata; Microinjections; Naltrexone; Narcotic Antagonists; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1997 |
Use of antisense oligodeoxynucleotide to delta-opioid receptor mRNA in the study of turnover of delta-opioid receptors in the spinal cord of the mouse.
Topics: Animals; Enkephalin, Methionine; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligonucleotides, Antisense; Oligopeptides; Pain Measurement; Protease Inhibitors; Receptors, Opioid, delta; RNA, Messenger; Spinal Cord; Thiorphan | 1997 |
Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Medulla Oblongata; Microinjections; Naltrexone; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 1997 |
Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors.
Topics: Animals; Benzylidene Compounds; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1998 |
Chronic naltrexone differentially affects supraspinal delta-opioid receptor-mediated antinociception.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Naltrexone; Narcotic Antagonists; Oligopeptides; Reaction Time; Receptors, Opioid, delta; Spinal Cord; Up-Regulation | 1998 |
Gestational and ovarian sex steroid antinociception: synergy between spinal kappa and delta opioid systems.
Topics: Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Estrogens; Female; Naltrexone; Narcotic Antagonists; Ovary; Pain Threshold; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Spinal Cord | 1998 |
Selective in vivo binding of [3H]naltriben to delta-opioid receptors in mouse brain.
Topics: Animals; Binding, Competitive; Brain; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta | 1998 |
Heroin antinociception changed from mu to delta receptor in streptozotocin-treated mice.
Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heroin; Injections, Intraventricular; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu; Streptozocin; Time Factors | 1998 |
Highly delta selective antagonists in the RVM attenuate the antinociceptive effect of PAG DAMGO.
Topics: Analgesics; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Medulla Oblongata; Naltrexone; Narcotic Antagonists; Neural Pathways; Oligopeptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Tetrahydroisoquinolines | 1999 |
The delta 2-opioid receptor antagonist naltriben reduces motivated responding for ethanol.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous System Depressants; Conditioning, Operant; Ethanol; Female; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Reinforcement Schedule | 1999 |
Involvement of spinal delta 1-opioid receptors in forced walking stress-induced antinociception in the tail-flick test in mice.
Topics: Analgesics; Animals; Benzylidene Compounds; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Stress, Physiological; Time Factors; Walking | 1999 |
Delta opioid receptor mediated actions in the rostral ventromedial medulla on tail flick latency and nociceptive modulatory neurons.
Topics: Animals; Dose-Response Relationship, Drug; Extracellular Space; Male; Medulla Oblongata; Naltrexone; Narcotic Antagonists; Neurons; Nociceptors; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, delta | 2000 |
Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray.
Topics: Amygdala; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Neurotensin; Nociceptors; Pain; Peptides; Periaqueductal Gray; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Valine | 2000 |
Opiate delta-2-receptor antagonist naltriben does not alter discriminative stimulus effects of ethanol.
Topics: Animals; Central Nervous System Depressants; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Self Administration | 2000 |
Pharmacological effects of naltriben as a ligand for opioid mu and kappa receptors in rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Ligands; Male; Naloxone; Naltrexone; Narcotic Antagonists; Norepinephrine; Peptide Fragments; Peptides; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Tritium | 2001 |
Contribution of endogenous enkephalins to the enhanced analgesic effects of supraspinal mu opioid receptor agonists after inflammatory injury.
Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Inflammation; Male; Microinjections; Naltrexone; Pain; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2001 |
Inverse agonist action of Leu-enkephalin at delta(2)-opioid receptors mediates spinal antianalgesia.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Cholecystokinin; Drug Tolerance; Enkephalin, Leucine; Excitatory Amino Acid Agonists; Male; Mice; Morphine; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Spinal Cord | 2001 |
Immunosuppression by delta-opioid antagonist naltrindole: delta- and triple mu/delta/kappa-opioid receptor knockout mice reveal a nonopioid activity.
Topics: Animals; Benzylidene Compounds; Cell Division; Concanavalin A; Dipeptides; Immunosuppressive Agents; Interleukin-2; Lymphocyte Culture Test, Mixed; Lymphocytes; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, sigma; T-Lymphocytes; Tetrahydroisoquinolines | 2001 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors | 2001 |
Administration of mu-, kappa- or delta2-receptor agonists via osmotic minipumps suppresses murine splenic antibody responses.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Antibody Formation; Depression, Chemical; Dose-Response Relationship, Drug; Female; Immunosuppressive Agents; Infusion Pumps; Mice; Mice, Inbred C3H; Morphine; Naltrexone; Neuroimmunomodulation; Oligopeptides; Osmosis; Peptide Fragments; Peptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spleen | 2001 |
Binding, pharmacological and immunological profiles of the delta-selective opioid receptor antagonist HS 378.
Topics: Animals; Brain; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Immunosuppressive Agents; Lymphocyte Activation; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; T-Lymphocytes | 2001 |
Chronic agonist treatment converts antagonists into inverse agonists at delta-opioid receptors.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cell Line; Cell Membrane; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Receptors, Opioid, delta; Receptors, Opioid, mu | 2002 |
Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Benzylidene Compounds; Convulsants; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Male; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Opioid, delta | 2002 |
Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Vagus Nerve | 2003 |
Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.
Topics: Animals; Benzylidene Compounds; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Immune Sera; Mice; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord | 2003 |
Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa.
Topics: Amphibian Proteins; Animals; Anions; Benzamides; Benzylidene Compounds; Biological Transport, Active; Carrier Proteins; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Gastrointestinal Motility; Ileum; Intestinal Mucosa; Male; Naltrexone; Neurons, Afferent; Oligopeptides; Piperazines; Quinolines; Receptors, Opioid, delta; Receptors, Opioid, mu; Swine; Tritium | 2003 |
Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus.
Topics: Analgesics, Opioid; Animals; Electric Stimulation; Female; Hot Temperature; Injections, Spinal; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Pathways; Nociceptors; Raphe Nuclei; Rats; Rats, Sprague-Dawley | 2004 |
delta-Opioid receptor antagonists inhibit GIRK channel currents in acutely dissociated brainstem neurons of rat.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guanosine 5'-O-(3-Thiotriphosphate); Ionophores; Locus Coeruleus; Naltrexone; Narcotic Antagonists; Neurons; Norepinephrine; Nystatin; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Raphe Nuclei; Rats; Serotonin; Thermolysin | 2004 |
Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Tetrodotoxin; Time Factors | 2004 |
Possible role of the phosphoinositide pathway for signal transduction in changes in the sensitivity of delta-opiate receptors during diabetes mellitus.
Topics: Benzylidene Compounds; Diabetes Mellitus; Diglycerides; Humans; In Vitro Techniques; Lymphocytes; Naltrexone; Oligopeptides; Phosphatidylinositols; Receptors, Opioid, delta; Signal Transduction | 2004 |
Role of delta-opioid receptor subtypes in anxiety-related behaviors in the elevated plus-maze in rats.
Topics: Animals; Anxiety; Benzamides; Benzylidene Compounds; Blood Specimen Collection; Corticosterone; Male; Maze Learning; Naltrexone; Piperazines; Rats; Rats, Inbred Lew; Receptors, Opioid, delta | 2005 |
delta-Opioid receptor agonist SNC80 elicits peripheral antinociception via delta(1) and delta(2) receptors and activation of the l-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzamides; Benzylidene Compounds; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Hyperalgesia; Male; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Rats; Receptors, Opioid, delta | 2005 |
Structural determination of the novel fragmentation routes of morphine opiate receptor antagonists using electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
Topics: Mesylates; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Spectrometry, Mass, Electrospray Ionization | 2005 |
Involvement of delta1-opioid receptors in the spatial learning impairment in streptozotocin-induced diabetic mice.
Topics: Animals; Benzylidene Compounds; Diabetes Mellitus, Experimental; Enkephalins; Escape Reaction; Mice; Naltrexone; Reaction Time; Receptors, Opioid, delta; Space Perception | 2005 |
Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway.
Topics: Animals; Appetite Regulation; Corn Oil; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides, Bacterial; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction | 2006 |
Selectivity of delta- and kappa-opioid ligands depends on the route of central administration in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzylidene Compounds; Enkephalin, D-Penicillamine (2,5)-; Injections, Intraventricular; Injections, Spinal; Ligands; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa | 2007 |
Methionine-enkephalin modulation of hydrogen peroxide (H2O2) release by rat peritoneal macrophages involves different types of opioid receptors.
Topics: Animals; Benzylidene Compounds; Carcinogens; Dose-Response Relationship, Drug; Enkephalin, Methionine; Hydrogen Peroxide; Macrophages, Peritoneal; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate | 2008 |
Dopamine-independent psychostimulant activity of a delta-agonist.
Topics: Animals; Benzamides; Brain; Central Nervous System Stimulants; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, delta | 2008 |
The mu opioid receptor mediates morphine-induced tumor necrosis factor and interleukin-6 inhibition in toll-like receptor 2-stimulated monocytes.
Topics: Cell Separation; Cells, Cultured; Cytokines; Humans; Inflammation; Interleukin-6; Monocytes; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha | 2008 |
Delta-opioid receptor antagonists prevent sensitization to the conditioned rewarding effects of morphine.
Topics: Analysis of Variance; Animals; Association Learning; Behavior, Animal; Benzylidene Compounds; Conditioning, Classical; Disease Models, Animal; Male; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Statistics, Nonparametric | 2009 |
Disruption of morphine-conditioned place preference by a delta2-opioid receptor antagonist: study of mu-opioid and delta-opioid receptor expression at the synapse.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Classical; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Subcellular Fractions; Synapses | 2010 |
Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ₂-opioid receptors, protein kinase C, and K(ATP) channels.
Topics: Animals; Benzophenanthridines; Benzylidene Compounds; Decanoic Acids; Glyburide; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Naltrexone; Oligopeptides; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Receptors, Opioid, delta | 2010 |
Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor trafficking.
Topics: Animals; Calcium; Endocytosis; HEK293 Cells; Humans; Ligands; Methadone; Mice; Naltrexone; Protein Transport; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction | 2011 |
The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions.
Topics: Analgesics; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzamides; Depression; Dopamine Antagonists; Imipramine; Male; Mice; Mice, Inbred ICR; Morphinans; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Receptors, Opioid, delta; Seizures; Swimming | 2011 |
DOR(2)-selective but not DOR(1)-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzylidene Compounds; Exploratory Behavior; Formaldehyde; Male; Maze Learning; Morphinans; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Nociception; Rats; Rats, Wistar; Receptors, Opioid, delta | 2014 |
Activation of TRPM7 channels by small molecules under physiological conditions.
Topics: Action Potentials; Animals; HEK293 Cells; Humans; Magnesium; Mice; Naltrexone; Phosphatidylinositol 4,5-Diphosphate; Small Molecule Libraries; TRPM Cation Channels | 2014 |
Implication of delta opioid receptor subtype 2 but not delta opioid receptor subtype 1 in the development of morphine analgesic tolerance in a rat model of chronic inflammatory pain.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Freund's Adjuvant; Hindlimb; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats, Sprague-Dawley; Receptors, Opioid, delta | 2015 |
Mibefradil represents a new class of benzimidazole TRPM7 channel agonists.
Topics: 1-Naphthylamine; Animals; Calcium; Calcium Channel Blockers; HEK293 Cells; Humans; Magnesium; Mibefradil; Mice; Naltrexone; TRPM Cation Channels | 2016 |
Function and regulation of TRPM7, as well as intracellular magnesium content, are altered in cells expressing ΔF508-CFTR and G551D-CFTR.
Topics: Adenosine Triphosphate; Calcium; Chloride Channels; Cymenes; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fura-2; Gene Expression Regulation; HeLa Cells; Humans; Kinetics; Magnesium; Monoterpenes; Mutagenesis, Site-Directed; Naltrexone; Patch-Clamp Techniques; Protein Interaction Maps; Protein Serine-Threonine Kinases; RNA, Messenger; TRPM Cation Channels | 2016 |
Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells.
Topics: Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Immunoblotting; Matrix Metalloproteinase 2; Membrane Potentials; Naltrexone; Neoplasm Invasiveness; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TRPM Cation Channels | 2017 |
TRPM7 Mediates Mechanosensitivity in Adult Rat Odontoblasts.
Topics: Animals; Fingolimod Hydrochloride; Gadolinium; Immunohistochemistry; Ionomycin; Male; Mechanotransduction, Cellular; Naltrexone; Odontoblasts; Radiometry; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Thapsigargin; Transient Receptor Potential Channels; TRPM Cation Channels | 2018 |
Modulation of Mg
Topics: 1-Naphthylamine; Animals; Calcium; Cell Line; Cytoplasm; HEK293 Cells; Humans; Magnesium; Male; Myocytes, Cardiac; Naltrexone; Rats; Rats, Wistar; TRPM Cation Channels | 2019 |
The Role of Cardiac Opioid Receptors in the Cardioprotective Effect of Continuous Normobaric Hypoxia.
Topics: Adaptation, Physiological; Animals; Benzylidene Compounds; Creatine Kinase; Hypoxia; Male; Myocardial Reperfusion Injury; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Organ Culture Techniques; Peptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrahydroisoquinolines | 2020 |
TRPM7-Mediated Calcium Transport in HAT-7 Ameloblasts.
Topics: Ameloblasts; Anilides; Animals; Calcium; Cell Line; Humans; Hydrogen-Ion Concentration; Incisor; Ion Channel Gating; Ion Transport; Mibefradil; Mice; Models, Biological; Naltrexone; Rats; Thiadiazoles; TRPM Cation Channels | 2021 |
Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy.
Topics: Apoptosis; Autophagosomes; Autophagy; Cell Proliferation; Clozapine; Humans; Lysosomes; Naltrexone; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Protein Serine-Threonine Kinases; R-SNARE Proteins; Signal Transduction; TRPM Cation Channels; Zinc | 2022 |