naltrexone and naltrindole benzofuran

naltrexone has been researched along with naltrindole benzofuran in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's49 (51.04)18.2507
2000's30 (31.25)29.6817
2010's14 (14.58)24.3611
2020's3 (3.13)2.80

Authors

AuthorsStudies
Portoghese, PS1
Lin, CE; MaloneyHuss, KE; Nagase, H; Portoghese, PS; Takemori, AE1
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L1
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A1
Strassburg, CP; Tukey, RH1
Fujii, H; Kobayashi, S; Miyata, Y; Nagase, H; Osa, Y; Takeuchi, T1
Iwata, S; Koyama, Y; Kutsumura, N; Miyata, Y; Nagase, H; Nagumo, Y; Nakajima, R; Saitoh, T; Yamamoto, N; Yoshida, N1
Nagase, H; Portoghese, PS; Sultana, M; Takemori, AE1
Portoghese, PS; Sofuoglu, M; Takemori, AE2
Freye, E; Latasch, L; Portoghese, PS1
Collins, KA; Portoghese, PS; Tsai, JH; Tseng, LF1
Froehlich, JC; Krishnan-Sarin, S; Li, TK; Portoghese, PS1
Hammond, DL; Littell, L; Stewart, PE1
Fujimoto, JM; Holmes, BB; Killian, P; Portoghese, PS; Takemori, AE1
Bergsbaken, C; Law, PY1
Funada, M; Misawa, M; Mori, T; Nagase, H; Suzuki, T1
Kamei, J; Misawa, M; Mizoguchi, H; Nagase, H; Suzuki, T; Yoshiike, M1
Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T1
Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M2
Crook, TJ; Hill, RG; Kitchen, I; Muhammad, BY1
Hammond, DL; Holper, EM; Stewart, PE1
Fujimoto, JM; Portoghese, PS; Rady, JJ; Takemori, AE1
Hammond, DL; Stewart, PE2
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T1
Portoghese, PS; Takemori, AE2
Bowen, WD; Carlisi, VJ; Hruby, VJ; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE; Wild, KD1
Miyamoto, Y; Portoghese, PS; Takemori, AE2
Collins, KA; Portoghese, PS; Tseng, LF1
Bhargava, HN; House, RV; Kozak, JT; Thomas, PT1
Kinter, CM; Lever, JR; Scheffel, U; Stathis, M1
Funada, M; Schutz, CG; Shippenberg, TS1
Mizoguchi, H; Nagase, H; Narita, M; Quock, RM; Suzuki, T; Tseng, LF1
Bhargava, HN; House, RV; Thomas, PT; Zhao, GM1
Baemmert, D; Fujimoto, JM; Portoghese, PS; Rady, JJ; Takemori, AE1
Hitosugi, H; Kamei, J; Kashiwazaki, T; Nagase, H1
Dawson-Basoa, M; Gintzler, AR2
Donahue, BB; Hammond, DL; Stewart, PE1
Mizoguchi, H; Nagase, H; Narita, M; Tseng, LF1
Hammond, DL; Thorat, SN1
Gross, GJ; Hsu, AK; Schultz, JE1
Inturrisi, CE; Jenab, S; Kao, B; Kest, B; Lee, CE1
Lever, JR; Scheffel, U1
Fujimoto, JM; Gorny, JM; Rady, JJ1
Fields, HL; Hirakawa, N; Tershner, SA1
Froehlich, JC; June, HL; Li, TK; McCane, SR; Portoghese, PS; Zink, RW1
Kamei, J; Nagase, H; Ohsawa, M; Onodera, K; Taki, K1
Fields, HL; Harasawa, I; Meng, ID1
Helmstetter, FJ; Tershner, SA1
Carl, K; Garrett, KM; Holloway, FA; Mhatre, MC1
Cho, KP; Kim, KW; Shin, BS; Son, Y1
Hammond, DL; Hurley, RW1
Fujimoto, JM; Holmes, BB; Rady, JJ; Tseng, LF1
Filliol, D; Gavériaux-Ruff, C; Kieffer, BL; Matthes, HW; Simonin, F1
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE1
Adler, MW; Cowan, A; Eisenstein, TK; Gaughan, J; Geller, EB; Meissler, JJ; Rahim, RT; Rogers, TJ1
Berzetei-Gurske, IP; Harris, HE; Klareskog, L; Schmidhammer, H; Spetea, M1
Liu, JG; Prather, PL1
Broom, DC; Nitsche, JF; Pintar, JE; Rice, KC; Traynor, JR; Woods, JH1
Caffrey, JL; Farias, M; Jackson, KE; Yoshishige, D1
Lunzer, MM; Portoghese, PS2
Brown, DR; Townsend, DW1
Laurito, CE; Lu, Y; Sweitzer, SM; Yeomans, DC1
Abe, K; Shirasaki, T; Soeda, F; Takahama, K1
Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Suzuki, T; Takada, K1
Agadjanov, MI; Agadjanova, EM; Batikyan, TB; Tadevosyan, YV; Vartanian, GS1
Kamei, J; Onodera, K; Saitoh, A; Yoshikawa, Y1
Castro, MS; Duarte, ID; Francischi, JN; Pacheco, DF; Perez, AC; Reis, GM1
Banoub, J; Cecchelli, R; El Aneed, A; Joly, N; Martin, P1
Kamei, J; Miyata, S; Saitoh, A; Takahashi, M1
Fushiki, T; Inoue, K; Matsumura, S; Mizushige, T; Tsuzuki, S; Yoneda, T1
Dimitrijević, M; Kovacević-Jovanović, V; Kustrimović, N; Miletić, T; Mitić, K; Stanojević, S; Vujić, V1
Ito, S; Mori, T; Sawaguchi, T1
Asehnoune, K; Beloeil, H; Benhamou, D; Bonnet, MP; Mazoit, JX1
Chefer, VI; Shippenberg, TS; Thompson, AC1
Billa, SK; Morón, JA; Xia, Y1
Barzakh, EI; Chernysheva, GA; Cybulnikov, SY; Krieg, T; Krylatov, AV; Lishmanov, AY; Maslov, LN; Solenkova, NV; Zhang, Y1
Milan-Lobo, L; Whistler, JL1
Fujii, H; Nagase, H; Nemoto, T; Oka, J; Saitoh, A; Sugiyama, A; Wada, K; Yamada, M1
Nagase, H; Oka, J; Saitoh, A; Sugiyama, A; Yamada, M1
Chubanov, V; Gudermann, T; Hofmann, T; Linseisen, M; Schäfer, S; Sytik, L1
Beaudry, H; Gendron, L; Morón, JA1
Chubanov, V; Ferioli, S; Gudermann, T; Hofmann, T; Schäfer, S; Zierler, S1
Benz, N; Buscaglia, P; Calvez, ML; Férec, C; Horgen, FD; Huguet, F; Kerbiriou, M; Le Hir, S; Mignen, O; Trouvé, P1
Feng, ZP; Rutka, JT; Sun, HS; Turlova, E; Wong, R1
Kang, Y; Kim, JH; Lee, PR; Oh, SB; Vang, H; Won, J1
Inoue, H; Konishi, M; Tashiro, M1
Maslov, LN; Naryzhnaya, NV; Nesterov, EA; Prokudina, ES; Tsibulnikov, SY1
DenBesten, P; Földes, A; Juhász, V; Kádár, K; Kató, E; Köles, L; Löchli, H; Rácz, R; Steward, MC; Varga, G; Zhang, Y; Zsembery, Á1
Cao, JL; Chen, R; Ding, L; Fei, YH; Guo, F; Jiang, Y; Liu, N; Liu, Y; Lu, C; Qi, J; Sui, Z; Wang, MM; Wang, W; Wang, X; Wang, Y; Wei, X; Wu, M; Xing, Y; Zhang, P; Zhang, Y1

Reviews

1 review(s) available for naltrexone and naltrindole benzofuran

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

95 other study(ies) available for naltrexone and naltrindole benzofuran

ArticleYear
An approach to the design of receptor-type-selective non-peptide antagonists of peptidergic receptors: delta opioid antagonists.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:6

    Topics: Amino Acid Sequence; Drug Design; Enkephalins; Indoles; Molecular Sequence Data; Morphinans; Naltrexone; Protein Conformation; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship

1991
Role of spacer and address components in peptidomimetic delta opioid receptor antagonists related to naltrindole.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Indoles; Male; Mice; Morphinans; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship

1991
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software

1994
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
    NIDA research monograph, 1998, Volume: 178

    Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders

1998
Opioid δ₁ receptor antagonist 7-benzylidenenaltrexone as an effective resistance reverser for chloroquine-resistant Plasmodium chabaudi.
    Bioorganic & medicinal chemistry letters, 2011, Aug-15, Volume: 21, Issue:16

    Topics: Antimalarials; Benzylidene Compounds; Chloroquine; Drug Resistance; Molecular Structure; Naltrexone; Parasitic Sensitivity Tests; Plasmodium chabaudi; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship

2011
Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives.
    Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16

    Topics: Animals; Antitrichomonal Agents; Benzylidene Compounds; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Molecular Structure; Naltrexone; Receptors, Opioid, delta; Structure-Activity Relationship; Trichomonas vaginalis

2017
Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone.
    Life sciences, 1992, Volume: 50, Issue:20

    Topics: Animals; Indoles; Ligands; Male; Mice; Morphinans; Morpholines; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa

1992
delta-Opioid receptor binding in mouse brain: evidence for heterogeneous binding sites.
    European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2

    Topics: Animals; Binding, Competitive; Brain Chemistry; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Membranes; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta

1992
The delta receptor is involved in sufentanil-induced respiratory depression--opioid subreceptors mediate different effects.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:6

    Topics: Animals; Carbon Dioxide; Dogs; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Indoles; Morphinans; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Nociceptors; Oxygen; Receptors, Opioid; Receptors, Opioid, delta; Respiration; Sufentanil

1992
Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:2

    Topics: Analgesia; Animals; Indoles; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta

1991
Spinal delta 2-, but not delta 1-, mu-, or kappa-opioid receptors are involved in the tail-flick inhibition induced by beta-endorphin from nucleus raphe obscurus in the pentobarbital-anesthetized rat.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Amino Acid Sequence; Analgesia; Animals; Benzylidene Compounds; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pentobarbital; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail

1995
The delta 2-opioid receptor antagonist naltriben selectively attenuates alcohol intake in rats bred for alcohol preference.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:1

    Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Brain Chemistry; Male; Naltrexone; Quinine; Rats; Rats, Wistar; Receptors, Opioid, delta

1995
Antinociception and delta-1 opioid receptors in the rat spinal cord: studies with intrathecal 7-benzylidenenaltrexone.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord

1995
Cold water swim stress- and delta-2 opioid-induced analgesia are modulated by spinal gamma-aminobutyric acidA receptors.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naltrexone; Picrotoxin; Receptors, GABA-A; Receptors, Opioid, delta; Spinal Cord; Stress, Physiological; Swimming

1995
Properties of delta opioid receptor in neuroblastoma NS20Y: receptor activation and neuroblastoma proliferation.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:1

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Division; Cyclic AMP; Humans; In Vitro Techniques; Mice; Naloxone; Naltrexone; Neuroblastoma; Pertussis Toxin; Receptors, Opioid, delta; Second Messenger Systems; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella

1995
Attenuation of the discriminative stimulus properties of cocaine by delta-opioid receptor antagonists.
    European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2

    Topics: Animals; Benzylidene Compounds; Cocaine; Discrimination Learning; Dose-Response Relationship, Drug; Male; Naltrexone; Rats; Rats, Inbred F344; Receptors, Opioid, delta

1994
Blockade of delta-opioid receptors prevents morphine-induced place preference in mice.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:1

    Topics: Analgesics; Animals; Benzylidene Compounds; Conditioning, Operant; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu

1994
Involvement of delta-opioid receptors in the effects of morphine on locomotor activity and the mesolimbic dopaminergic system in mice.
    Psychopharmacology, 1993, Volume: 111, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Dopamine; Homovanillic Acid; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Postural Balance; Reaction Time; Receptors, Opioid, delta

1993
The role of delta-opioid receptor subtypes in cocaine- and methamphetamine-induced place preferences.
    Life sciences, 1994, Volume: 55, Issue:17

    Topics: Animals; Benzylidene Compounds; Cocaine; Conditioning, Psychological; Male; Methamphetamine; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reinforcement, Psychology

1994
Evidence that weaning stimulates the developmental expression of a delta-opioid receptor subtype in the rat.
    Brain research. Developmental brain research, 1994, Mar-18, Volume: 78, Issue:1

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Female; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Weaning

1994
Delta antagonist and kappa agonist activity of Naltriben: evidence for differential kappa interaction with the delta 1 and delta 2 opioid receptor subtypes.
    Life sciences, 1994, Volume: 55, Issue:4

    Topics: Animals; Male; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa

1994
Supraspinal delta receptor subtype activity of heroin and 6-monoacetylmorphine in Swiss Webster mice.
    Life sciences, 1994, Volume: 55, Issue:8

    Topics: Animals; Benzylidene Compounds; Heroin; Male; Mice; Morphine Derivatives; Naltrexone; Pain; Receptors, Opioid, delta

1994
Activation of spinal delta-1 or delta-2 opioid receptors reduces carrageenan-induced hyperalgesia in the rat.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2

    Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Male; Naltrexone; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord

1994
Involvement of delta 1-opioid receptor antagonism in the antitussive effect of delta-opioid receptor antagonists.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: Animals; Antitussive Agents; Benzylidene Compounds; Capsaicin; Cough; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta

1994
Enkephalin antinociception in mice is mediated by delta 1- and delta 2-opioid receptors in the brain and spinal cord, respectively.
    European journal of pharmacology, 1993, Sep-28, Volume: 242, Issue:2

    Topics: Animals; Benzylidene Compounds; beta-Endorphin; Brain; Enkephalin, Leucine; Enkephalin, Methionine; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naltrexone; Pain; Receptors, Opioid, delta; Spinal Cord

1993
Evidence for a single functional opioid delta receptor subtype in the mouse isolated vas deferens.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Animals; Benzylidene Compounds; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Morphinans; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Thiocyanates; Vas Deferens

1993
Involvement of delta 2 opioid receptors in the development of morphine dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: Animals; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphinans; Morphine Dependence; Naloxone; Naltrexone; Receptors, Opioid, delta; Substance Withdrawal Syndrome; Thiocyanates

1993
Spinal delta 2 but not delta 1 opioid receptors are involved in intracerebroventricular beta-endorphin-induced antinociception in the mouse.
    Life sciences, 1993, Volume: 52, Issue:19

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzylidene Compounds; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Pyrrolidines; Receptors, Opioid, delta; Spinal Cord

1993
Involvement of delta 2 opioid receptors in acute dependence on morphine in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

    Topics: Animals; Drug Interactions; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphine; Naltrexone; Receptors, Opioid, delta; Substance-Related Disorders; Thiocyanates

1993
Evidence for delta opioid receptor subtypes in rat spinal cord: studies with intrathecal naltriben, cyclic[D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Reflex; Spinal Cord

1993
The mixed antinociceptive agonist-antagonist activity of beta-endorphin(1-27) in mice.
    Life sciences, 1993, Volume: 53, Issue:13

    Topics: Animals; Benzylidene Compounds; beta-Endorphin; Male; Mice; Naltrexone; Narcotic Antagonists; Nociceptors; Peptide Fragments; Receptors, Opioid

1993
Suppression of immune function by non-peptidic delta opioid receptor antagonists.
    Neuroscience letters, 1995, Sep-29, Volume: 198, Issue:2

    Topics: Animals; B-Lymphocytes; Female; Immunosuppressive Agents; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Spleen; T-Lymphocytes, Helper-Inducer

1995
In vivo labeling of delta opioid receptors in mouse brain by [3H]benzylidenenaltrexone, a ligand selective for the delta 1 subtype.
    Life sciences, 1996, Volume: 58, Issue:21

    Topics: Animals; Benzylidene Compounds; Corpus Striatum; Male; Mice; Naltrexone; Radioligand Assay; Receptors, Opioid, delta; Tritium

1996
Role of delta-opioid receptors in mediating the aversive stimulus effects of morphine withdrawal in the rat.
    European journal of pharmacology, 1996, Apr-04, Volume: 300, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substance Withdrawal Syndrome

1996
Use of antisense oligodeoxynucleotide to determine delta-opioid receptor involvement in [D-Ala2]deltorphin II-induced locomotor hyperactivity.
    Life sciences, 1996, Volume: 59, Issue:4

    Topics: Amino Acid Sequence; Analysis of Variance; Animals; Base Sequence; Benzylidene Compounds; Cerebral Ventricles; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Motor Activity; Naltrexone; Narcotic Antagonists; Oligonucleotides, Antisense; Oligopeptides; Receptors, Opioid, delta; Somatostatin; Thionucleotides

1996
Effects of chronic administration of 7-benzylidene-7-dehydronaltrexone and naltriben on the antinociceptive actions of delta 1- and delta 2-opioid receptor agonists.
    European journal of pharmacology, 1996, Sep-12, Volume: 311, Issue:2-3

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Enkephalins; Female; Membranes; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Receptors, Opioid; Receptors, Opioid, delta

1996
Spinal delta opioid receptor subtype activity of 6-monoacetylmorphine in Swiss Webster mice.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:2

    Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; beta-Endorphin; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Spinal Cord

1997
The role of spinal delta1-opioid receptors in inhibiting the formalin-induced nociceptive response in diabetic mice.
    European journal of pharmacology, 1997, May-12, Volume: 326, Issue:1

    Topics: Analgesics; Animals; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Formaldehyde; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Spinal Cord

1997
Involvement of spinal cord delta opiate receptors in the antinociception of gestation and its hormonal simulation.
    Brain research, 1997, May-16, Volume: 757, Issue:1

    Topics: Animals; Benzylidene Compounds; Female; Humans; Injections, Spinal; Male; Naltrexone; Narcotic Antagonists; Pain; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Sensory Thresholds; Sex Characteristics; Spinal Cord; Time Factors

1997
The role of delta-opioid receptors in the discriminative stimulus properties of a low dose of methamphetamine.
    European journal of pharmacology, 1997, Jul-16, Volume: 331, Issue:1

    Topics: Animals; Benzylidene Compounds; Central Nervous System Stimulants; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Methamphetamine; Naltrexone; Quinolines; Rats; Rats, Inbred F344; Receptors, Opioid, delta

1997
Role of spinal delta1 and delta2 opioid receptors in the antinociception produced by microinjection of L-glutamate in the ventromedial medulla of the rat.
    Brain research, 1997, Aug-08, Volume: 765, Issue:1

    Topics: Analgesics; Animals; Benzylidene Compounds; Glutamic Acid; Isothiocyanates; Male; Medulla Oblongata; Microinjections; Naltrexone; Narcotic Antagonists; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord

1997
Use of antisense oligodeoxynucleotide to delta-opioid receptor mRNA in the study of turnover of delta-opioid receptors in the spinal cord of the mouse.
    Psychopharmacology, 1997, Volume: 133, Issue:4

    Topics: Animals; Enkephalin, Methionine; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligonucleotides, Antisense; Oligopeptides; Pain Measurement; Protease Inhibitors; Receptors, Opioid, delta; RNA, Messenger; Spinal Cord; Thiorphan

1997
Modulation of nociception by microinjection of delta-1 and delta-2 opioid receptor ligands in the ventromedial medulla of the rat.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3

    Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Medulla Oblongata; Microinjections; Naltrexone; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta

1997
Ischemic preconditioning in the intact rat heart is mediated by delta1- but not mu- or kappa-opioid receptors.
    Circulation, 1998, Apr-07, Volume: 97, Issue:13

    Topics: Animals; Benzylidene Compounds; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1998
Chronic naltrexone differentially affects supraspinal delta-opioid receptor-mediated antinociception.
    European journal of pharmacology, 1998, Mar-12, Volume: 345, Issue:1

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Naltrexone; Narcotic Antagonists; Oligopeptides; Reaction Time; Receptors, Opioid, delta; Spinal Cord; Up-Regulation

1998
Gestational and ovarian sex steroid antinociception: synergy between spinal kappa and delta opioid systems.
    Brain research, 1998, May-25, Volume: 794, Issue:1

    Topics: Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Estrogens; Female; Naltrexone; Narcotic Antagonists; Ovary; Pain Threshold; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Spinal Cord

1998
Selective in vivo binding of [3H]naltriben to delta-opioid receptors in mouse brain.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: Animals; Binding, Competitive; Brain; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta

1998
Heroin antinociception changed from mu to delta receptor in streptozotocin-treated mice.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:4

    Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heroin; Injections, Intraventricular; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu; Streptozocin; Time Factors

1998
Highly delta selective antagonists in the RVM attenuate the antinociceptive effect of PAG DAMGO.
    Neuroreport, 1999, Oct-19, Volume: 10, Issue:15

    Topics: Analgesics; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Medulla Oblongata; Naltrexone; Narcotic Antagonists; Neural Pathways; Oligopeptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Tetrahydroisoquinolines

1999
The delta 2-opioid receptor antagonist naltriben reduces motivated responding for ethanol.
    Psychopharmacology, 1999, Volume: 147, Issue:1

    Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous System Depressants; Conditioning, Operant; Ethanol; Female; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Reinforcement Schedule

1999
Involvement of spinal delta 1-opioid receptors in forced walking stress-induced antinociception in the tail-flick test in mice.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:9

    Topics: Analgesics; Animals; Benzylidene Compounds; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Stress, Physiological; Time Factors; Walking

1999
Delta opioid receptor mediated actions in the rostral ventromedial medulla on tail flick latency and nociceptive modulatory neurons.
    Pain, 2000, Volume: 85, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Extracellular Space; Male; Medulla Oblongata; Naltrexone; Narcotic Antagonists; Neurons; Nociceptors; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, delta

2000
Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray.
    Brain research, 2000, May-19, Volume: 865, Issue:1

    Topics: Amygdala; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Neurotensin; Nociceptors; Pain; Peptides; Periaqueductal Gray; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Opioid, delta; Receptors, Opioid, mu; Time Factors; Valine

2000
Opiate delta-2-receptor antagonist naltriben does not alter discriminative stimulus effects of ethanol.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:4

    Topics: Animals; Central Nervous System Depressants; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Self Administration

2000
Pharmacological effects of naltriben as a ligand for opioid mu and kappa receptors in rat cerebral cortex.
    Life sciences, 2001, Feb-02, Volume: 68, Issue:11

    Topics: Animals; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Ligands; Male; Naloxone; Naltrexone; Narcotic Antagonists; Norepinephrine; Peptide Fragments; Peptides; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Tritium

2001
Contribution of endogenous enkephalins to the enhanced analgesic effects of supraspinal mu opioid receptor agonists after inflammatory injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-01, Volume: 21, Issue:7

    Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Inflammation; Male; Microinjections; Naltrexone; Pain; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin

2001
Inverse agonist action of Leu-enkephalin at delta(2)-opioid receptors mediates spinal antianalgesia.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:2

    Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Cholecystokinin; Drug Tolerance; Enkephalin, Leucine; Excitatory Amino Acid Agonists; Male; Mice; Morphine; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Spinal Cord

2001
Immunosuppression by delta-opioid antagonist naltrindole: delta- and triple mu/delta/kappa-opioid receptor knockout mice reveal a nonopioid activity.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:3

    Topics: Animals; Benzylidene Compounds; Cell Division; Concanavalin A; Dipeptides; Immunosuppressive Agents; Interleukin-2; Lymphocyte Culture Test, Mixed; Lymphocytes; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, sigma; T-Lymphocytes; Tetrahydroisoquinolines

2001
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
    European journal of pharmacology, 2001, Sep-21, Volume: 427, Issue:3

    Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors

2001
Administration of mu-, kappa- or delta2-receptor agonists via osmotic minipumps suppresses murine splenic antibody responses.
    International immunopharmacology, 2001, Volume: 1, Issue:11

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Antibody Formation; Depression, Chemical; Dose-Response Relationship, Drug; Female; Immunosuppressive Agents; Infusion Pumps; Mice; Mice, Inbred C3H; Morphine; Naltrexone; Neuroimmunomodulation; Oligopeptides; Osmosis; Peptide Fragments; Peptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spleen

2001
Binding, pharmacological and immunological profiles of the delta-selective opioid receptor antagonist HS 378.
    Life sciences, 2001, Aug-31, Volume: 69, Issue:15

    Topics: Animals; Brain; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Immunosuppressive Agents; Lymphocyte Activation; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; T-Lymphocytes

2001
Chronic agonist treatment converts antagonists into inverse agonists at delta-opioid receptors.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cell Line; Cell Membrane; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Receptors, Opioid, delta; Receptors, Opioid, mu

2002
Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Benzylidene Compounds; Convulsants; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Male; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Opioid, delta

2002
Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Vagus Nerve

2003
Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Animals; Benzylidene Compounds; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Immune Sera; Mice; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord

2003
Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa.
    British journal of pharmacology, 2003, Volume: 140, Issue:4

    Topics: Amphibian Proteins; Animals; Anions; Benzamides; Benzylidene Compounds; Biological Transport, Active; Carrier Proteins; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Gastrointestinal Motility; Ileum; Intestinal Mucosa; Male; Naltrexone; Neurons, Afferent; Oligopeptides; Piperazines; Quinolines; Receptors, Opioid, delta; Receptors, Opioid, mu; Swine; Tritium

2003
Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Analgesics, Opioid; Animals; Electric Stimulation; Female; Hot Temperature; Injections, Spinal; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Pathways; Nociceptors; Raphe Nuclei; Rats; Rats, Sprague-Dawley

2004
delta-Opioid receptor antagonists inhibit GIRK channel currents in acutely dissociated brainstem neurons of rat.
    Brain research, 2004, May-01, Volume: 1006, Issue:2

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guanosine 5'-O-(3-Thiotriphosphate); Ionophores; Locus Coeruleus; Naltrexone; Narcotic Antagonists; Neurons; Norepinephrine; Nystatin; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Raphe Nuclei; Rats; Serotonin; Thermolysin

2004
Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms.
    European journal of pharmacology, 2004, Apr-26, Volume: 491, Issue:1

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Tetrodotoxin; Time Factors

2004
Possible role of the phosphoinositide pathway for signal transduction in changes in the sensitivity of delta-opiate receptors during diabetes mellitus.
    Bulletin of experimental biology and medicine, 2004, Volume: 137, Issue:2

    Topics: Benzylidene Compounds; Diabetes Mellitus; Diglycerides; Humans; In Vitro Techniques; Lymphocytes; Naltrexone; Oligopeptides; Phosphatidylinositols; Receptors, Opioid, delta; Signal Transduction

2004
Role of delta-opioid receptor subtypes in anxiety-related behaviors in the elevated plus-maze in rats.
    Psychopharmacology, 2005, Volume: 182, Issue:3

    Topics: Animals; Anxiety; Benzamides; Benzylidene Compounds; Blood Specimen Collection; Corticosterone; Male; Maze Learning; Naltrexone; Piperazines; Rats; Rats, Inbred Lew; Receptors, Opioid, delta

2005
delta-Opioid receptor agonist SNC80 elicits peripheral antinociception via delta(1) and delta(2) receptors and activation of the l-arginine/nitric oxide/cyclic GMP pathway.
    Life sciences, 2005, Nov-19, Volume: 78, Issue:1

    Topics: Analgesics; Animals; Arginine; Benzamides; Benzylidene Compounds; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Hyperalgesia; Male; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Rats; Receptors, Opioid, delta

2005
Structural determination of the novel fragmentation routes of morphine opiate receptor antagonists using electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2005, Volume: 19, Issue:21

    Topics: Mesylates; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Spectrometry, Mass, Electrospray Ionization

2005
Involvement of delta1-opioid receptors in the spatial learning impairment in streptozotocin-induced diabetic mice.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2005, Volume: 25, Issue:5

    Topics: Animals; Benzylidene Compounds; Diabetes Mellitus, Experimental; Enkephalins; Escape Reaction; Mice; Naltrexone; Reaction Time; Receptors, Opioid, delta; Space Perception

2005
Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway.
    Biomedical research (Tokyo, Japan), 2006, Volume: 27, Issue:6

    Topics: Animals; Appetite Regulation; Corn Oil; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides, Bacterial; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction

2006
Selectivity of delta- and kappa-opioid ligands depends on the route of central administration in mice.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzylidene Compounds; Enkephalin, D-Penicillamine (2,5)-; Injections, Intraventricular; Injections, Spinal; Ligands; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa

2007
Methionine-enkephalin modulation of hydrogen peroxide (H2O2) release by rat peritoneal macrophages involves different types of opioid receptors.
    Neuropeptides, 2008, Volume: 42, Issue:2

    Topics: Animals; Benzylidene Compounds; Carcinogens; Dose-Response Relationship, Drug; Enkephalin, Methionine; Hydrogen Peroxide; Macrophages, Peritoneal; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetradecanoylphorbol Acetate

2008
Dopamine-independent psychostimulant activity of a delta-agonist.
    Behavioural pharmacology, 2008, Volume: 19, Issue:2

    Topics: Animals; Benzamides; Brain; Central Nervous System Stimulants; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Male; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Piperazines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, delta

2008
The mu opioid receptor mediates morphine-induced tumor necrosis factor and interleukin-6 inhibition in toll-like receptor 2-stimulated monocytes.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:4

    Topics: Cell Separation; Cells, Cultured; Cytokines; Humans; Inflammation; Interleukin-6; Monocytes; Morphine; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha

2008
Delta-opioid receptor antagonists prevent sensitization to the conditioned rewarding effects of morphine.
    Biological psychiatry, 2009, Jan-15, Volume: 65, Issue:2

    Topics: Analysis of Variance; Animals; Association Learning; Behavior, Animal; Benzylidene Compounds; Conditioning, Classical; Disease Models, Animal; Male; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Statistics, Nonparametric

2009
Disruption of morphine-conditioned place preference by a delta2-opioid receptor antagonist: study of mu-opioid and delta-opioid receptor expression at the synapse.
    The European journal of neuroscience, 2010, Volume: 32, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Classical; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Subcellular Fractions; Synapses

2010
Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ₂-opioid receptors, protein kinase C, and K(ATP) channels.
    Bulletin of experimental biology and medicine, 2010, Volume: 149, Issue:5

    Topics: Animals; Benzophenanthridines; Benzylidene Compounds; Decanoic Acids; Glyburide; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Naltrexone; Oligopeptides; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Receptors, Opioid, delta

2010
Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor trafficking.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:3

    Topics: Animals; Calcium; Endocytosis; HEK293 Cells; Humans; Ligands; Methadone; Mice; Naltrexone; Protein Transport; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction

2011
The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions.
    Behavioural brain research, 2011, Oct-01, Volume: 223, Issue:2

    Topics: Analgesics; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzamides; Depression; Dopamine Antagonists; Imipramine; Male; Mice; Mice, Inbred ICR; Morphinans; Motor Activity; Naltrexone; Narcotic Antagonists; Pain Measurement; Piperazines; Receptors, Opioid, delta; Seizures; Swimming

2011
DOR(2)-selective but not DOR(1)-selective antagonist abolishes anxiolytic-like effects of the δ opioid receptor agonist KNT-127.
    Neuropharmacology, 2014, Volume: 79

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzylidene Compounds; Exploratory Behavior; Formaldehyde; Male; Maze Learning; Morphinans; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Nociception; Rats; Rats, Wistar; Receptors, Opioid, delta

2014
Activation of TRPM7 channels by small molecules under physiological conditions.
    Pflugers Archiv : European journal of physiology, 2014, Volume: 466, Issue:12

    Topics: Action Potentials; Animals; HEK293 Cells; Humans; Magnesium; Mice; Naltrexone; Phosphatidylinositol 4,5-Diphosphate; Small Molecule Libraries; TRPM Cation Channels

2014
Implication of delta opioid receptor subtype 2 but not delta opioid receptor subtype 1 in the development of morphine analgesic tolerance in a rat model of chronic inflammatory pain.
    The European journal of neuroscience, 2015, Volume: 41, Issue:7

    Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Freund's Adjuvant; Hindlimb; Inflammation; Male; Morphine; Naltrexone; Narcotic Antagonists; Rats, Sprague-Dawley; Receptors, Opioid, delta

2015
Mibefradil represents a new class of benzimidazole TRPM7 channel agonists.
    Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:4

    Topics: 1-Naphthylamine; Animals; Calcium; Calcium Channel Blockers; HEK293 Cells; Humans; Magnesium; Mibefradil; Mice; Naltrexone; TRPM Cation Channels

2016
Function and regulation of TRPM7, as well as intracellular magnesium content, are altered in cells expressing ΔF508-CFTR and G551D-CFTR.
    Cellular and molecular life sciences : CMLS, 2016, Volume: 73, Issue:17

    Topics: Adenosine Triphosphate; Calcium; Chloride Channels; Cymenes; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fura-2; Gene Expression Regulation; HeLa Cells; Humans; Kinetics; Magnesium; Monoterpenes; Mutagenesis, Site-Directed; Naltrexone; Patch-Clamp Techniques; Protein Interaction Maps; Protein Serine-Threonine Kinases; RNA, Messenger; TRPM Cation Channels

2016
Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Immunoblotting; Matrix Metalloproteinase 2; Membrane Potentials; Naltrexone; Neoplasm Invasiveness; Patch-Clamp Techniques; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TRPM Cation Channels

2017
TRPM7 Mediates Mechanosensitivity in Adult Rat Odontoblasts.
    Journal of dental research, 2018, Volume: 97, Issue:9

    Topics: Animals; Fingolimod Hydrochloride; Gadolinium; Immunohistochemistry; Ionomycin; Male; Mechanotransduction, Cellular; Naltrexone; Odontoblasts; Radiometry; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Thapsigargin; Transient Receptor Potential Channels; TRPM Cation Channels

2018
Modulation of Mg
    The journal of physiological sciences : JPS, 2019, Volume: 69, Issue:1

    Topics: 1-Naphthylamine; Animals; Calcium; Cell Line; Cytoplasm; HEK293 Cells; Humans; Magnesium; Male; Myocytes, Cardiac; Naltrexone; Rats; Rats, Wistar; TRPM Cation Channels

2019
The Role of Cardiac Opioid Receptors in the Cardioprotective Effect of Continuous Normobaric Hypoxia.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:6

    Topics: Adaptation, Physiological; Animals; Benzylidene Compounds; Creatine Kinase; Hypoxia; Male; Myocardial Reperfusion Injury; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Organ Culture Techniques; Peptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrahydroisoquinolines

2020
TRPM7-Mediated Calcium Transport in HAT-7 Ameloblasts.
    International journal of molecular sciences, 2021, Apr-13, Volume: 22, Issue:8

    Topics: Ameloblasts; Anilides; Animals; Calcium; Cell Line; Humans; Hydrogen-Ion Concentration; Incisor; Ion Channel Gating; Ion Transport; Mibefradil; Mice; Models, Biological; Naltrexone; Rats; Thiadiazoles; TRPM Cation Channels

2021
Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy.
    Cancer letters, 2022, 01-28, Volume: 525

    Topics: Apoptosis; Autophagosomes; Autophagy; Cell Proliferation; Clozapine; Humans; Lysosomes; Naltrexone; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Protein Serine-Threonine Kinases; R-SNARE Proteins; Signal Transduction; TRPM Cation Channels; Zinc

2022