naltrexone has been researched along with naloxone in 1434 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 657 (45.82) | 18.7374 |
1990's | 386 (26.92) | 18.2507 |
2000's | 222 (15.48) | 29.6817 |
2010's | 138 (9.62) | 24.3611 |
2020's | 31 (2.16) | 2.80 |
Authors | Studies |
---|---|
Berkowitz, DS; Loew, GH | 1 |
Dasher, WE; Klein, P; Nelson, WL | 1 |
Klein, P; Nelson, WL | 2 |
Klein, P; Nelson, WL; Olsen, LD; Simon, EJ; Yao, YH | 1 |
Galzi, JL; Goeldner, M; Hirth, C; Ilien, B; Mejean, A; Meunier, JC; Mollereau, C | 1 |
Burkard, WP; Eggstein-Aeppli, L; Schmidhammer, H; Smith, CF | 1 |
Cheney, BV | 1 |
Hahn, EF; Pasternak, GW | 1 |
Alreja, BD; Larson, DL; Portoghese, PS | 1 |
Carling, RW; Kobylecki, RJ; Lane, AC; Lord, JA; Smith, CF | 1 |
Portoghese, PS; Takemori, AE | 4 |
Bousquet, AR; Howes, JF; Kotick, MP; Polazzi, JO | 1 |
Archer, S; Gillan, MG; Kosterlitz, HW; Osei-Gyimah, P | 1 |
Befort, K; Bloch, B; Charron, G; Gavériaux-Ruff, C; Kieffer, B; Lannes, B; Mattéi, MG; Matthes, H; Micheletti, G; Simonin, F | 1 |
Cantrell, BE; Gidda, JS; Johnson, BG; Leander, JD; Schoepp, DD; Zimmerman, DM | 1 |
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
Bell, GI; Breder, CD; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yasuda, K | 1 |
Cantrell, BE; Johnson, BG; Leander, JD; Mendelsohn, LG; Mitch, CH; Reel, JK; Snoddy, J; Zimmerman, DM | 1 |
Cantrell, BE; Johnson, BG; Leander, JD; Mendelsohn, LG; Mitch, CH; Reel, JK; Shaw, WN; Snoddy, JD; Takemori, AE; Wong, DT | 1 |
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Belanger, S; DeHaven, RN; Dolle, RE; Goodman, AJ; Graczyk, TM; Herbertz, T; Le Bourdonnec, B; Michaut, M; Yap, GP; Ye, HF | 1 |
Belanger, S; DeHaven, RN; Dolle, RE; Goodman, AJ; Graczyk, TM; Le Bourdonnec, B; Seida, PR | 1 |
Hebbel, RP; Lunzer, MM; Portoghese, PS; Yekkirala, A | 1 |
Bidlack, JM; Knapp, BI; Neumeyer, JL; Peng, X | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Aceto, MD; Coop, A; Harris, LS; May, EL; Metcalf, MD; Traynor, JR; Woods, JH | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Bidlack, JM; Bu, Y; Cohen, DJ; Lou, R; Lu, Q; VanAlstine, MA; Wentland, MP | 1 |
Aschenbach, LC; Cassidy, MP; Chen, J; Dewey, WL; Gabra, BH; Li, G; Selley, DE; Stevens, DL; Westkaemper, RB; Zhang, Y | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Bittman, RW; Cheng, K; Dersch, CM; Jacobson, AE; Lee, YS; Rice, KC; Rothman, RB | 1 |
Burgman, M; Grinnell, S; Haselton, N; Majumdar, S; Ocampo, J; Pasternak, AR; Pasternak, GW | 1 |
Fujii, H; Hirayama, S; Koyano, K; Mochizuki, H; Nagase, H; Nakajima, M; Nakao, K; Nemoto, T; Wada, N; Watanabe, A | 1 |
Burgman, M; Grinnell, S; Haselton, N; Le Rouzic, V; Majumdar, S; Nagakura, K; Ocampo, J; Pan, YX; Pasternak, AR; Pasternak, GW; Polikar, L; Subrath, J | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Aschenbach, LC; Dewey, WL; Elbegdorj, O; Li, G; Scoggins, KL; Selley, DE; Stevens, DL; Yuan, Y; Zaidi, SA; Zhang, Y | 1 |
Coop, A; Cunningham, CW; Eddington, ND; Hassan, HE; Mercer, SL; Metcalf, MD; Rosicky, AD | 1 |
Briddon, SJ; Canals, M; Graham, B; Kellam, B; Scammells, PJ; Schembri, LS; Stoddart, LA | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Costa, E; Guidotti, A; Racagni, G; Zsilla, G | 1 |
Geller, I; Hartmann, RJ | 1 |
Capozza, RC; Schmitt, EE; Sendelbeck, LR | 1 |
Brodin, AF; Frank, SG | 1 |
Ahtee, L; Carlsson, A; Garcia-Sevilla, JA; Magnusson, T | 1 |
Carino, MA; Horita, A | 1 |
Resnick, RB; Volavka, J | 1 |
Greenstein, R; O'Brien, C | 1 |
Fishman, J; Foldes, FF; Hahn, EF; Ronai, AZ | 1 |
Caruso, TP; Larson, DL; Portoghese, PS; Takemori, AE | 3 |
Grabowski, J; Greenstein, R; McLellan, AT; O'Brien, CP; Ternes, J | 1 |
Julius, DA | 3 |
Ling, W | 1 |
Renault, PF | 2 |
Zimmering, S | 1 |
Ashcraft, SB; Bathala, MS; Batra, VK; Harrigan, SE; Jao, MY; Ludden, TM; Malspeis, L; McCarthy, DA; Morrison, BE; Reuning, RH; Sams, RA; Staubus, AE | 1 |
Aylsworth, CF; Hodson, CA; Meites, J | 1 |
Smith, JB | 2 |
Callahan, EJ; Glazer, M; Liberman, RP; Rawson, RA | 1 |
Mulé, SJ; Verebey, K | 2 |
Ellingboe, J; Kuehnle, J; Mello, NK; Mendelson, JH | 1 |
Grabowski, J; Greenstein, R; Long, M; O'Brien, CP; Steinberg-Donato, S; Ternes, J | 2 |
Calne, DB; Chase, TN; Eisler, T; Nutt, JG; Rosin, AJ | 1 |
Braude, M; Brockman, H; Brusick, D; Jagannath, D; Matheson, D | 1 |
Altman, JL; Meyer, RE; Mirin, SM | 1 |
Altman, JL; McNamee, HB; Meyer, RE; Mirin, SM | 3 |
Ary, M; Chesarek, W; Lomax, P; Sorensen, SM | 1 |
Terenius, L; Wahlstrom, A | 1 |
Goldstein, A | 2 |
Bell, J; Gilbert, P; Martin, W; Sloan, J; Thompson, J | 1 |
Julius, D | 1 |
Craviso, GL; Gascon, P; Musacchio, JM; Puig, MM | 1 |
Archer, S; Michne, WF | 1 |
Costa, E; Dill, RE | 1 |
Terenius, L | 2 |
Herz, A; Höllt, V | 1 |
Järbe, TU; Ohlin, GC | 1 |
Wikler, A | 2 |
Grandison, L; Guidotti, A | 1 |
Caruso, TP; Jiang, JB; Larson, DL; Portoghese, PS; Takemori, AE | 2 |
Abood, LG; Butler, M; MacNeil, M; Salem, N | 1 |
Bailey, B; Diaz, J; Frenk, H; Paul, L | 1 |
Akil, H; Barchas, JD; Berger, PA; Watson, SJ | 1 |
Martin, WR | 2 |
Greenstein, R; O'Brien, CP; Woody, GE | 1 |
Kestenbaum, RS; Resnick, RB; Thomas, MA; Washton, AM | 1 |
Willette, RE | 1 |
Ellingboe, J; Keuhnle, JC; Mello, NK; Mendelson, JH | 1 |
Frank, GB; Marwaha, J | 1 |
Bauman, J; Cho, D; Dornbush, R; James, B; Mallya, A; Pevnick, J; Reker, D; Volavka, J | 1 |
Iversen, LL; Reisine, TD; Rossor, M; Spokes, E; Yamamura, HI | 1 |
Mackay, AV | 1 |
Jukofsky, D; Mulé, SJ; Verebely, K | 1 |
Resnick, RB; Washton, AM | 1 |
Buchsbaum, MS; Bunney, WE; Davis, GC; van Kammen, DP | 1 |
Greenstein, R; O'Brien, CP; Ternes, J; Woody, GE | 1 |
Cicero, TJ; Meyer, ER; Schainker, BA | 1 |
Friesen, HG; Panerai, AE; Tannenbaum, GS | 1 |
Downs, DA; Harrigan, SE | 1 |
Kosterlitz, HW | 2 |
Katz, RJ | 1 |
Berkowitz, BA; Hynes, MD | 1 |
Järbe, TU; Loman, P; Swedberg, MD | 1 |
Baum, MJ; Myers, BM | 1 |
Kosterlitz, HW; Leslie, FM | 1 |
Fennessy, MR; Laska, FJ | 1 |
Bhargava, HN | 2 |
Amir, S; Amit, Z | 1 |
Gerber, N; Lynn, RK; Rodgers, RM; Taylor, SM | 2 |
Brahen, LS; Capone, T; Wojak, JC | 1 |
Amir, S; Amit, Z; Blair, R | 1 |
Lehman, TM; Peterson, GR; Pyati, P | 1 |
Frenk, H; Rosen, JB | 1 |
Harry, GJ; Rosecrans, JA | 1 |
Amir, S; Amit, Z; Galina, HZ | 1 |
Bajusz, S; Berzétei, I; Rónai, AZ | 1 |
Gilbert, PE; Martin, WR | 2 |
Cho, D; James, B; Mallya, A; Pevnick, J; Reker, D; Volavka, J | 1 |
Gellert, VF; Holtzman, SG | 1 |
Resnick, RB | 1 |
Gitlin, M; Rosenblatt, M | 1 |
Brodin, AF; Frank, SG; Kavaliunas, DR | 1 |
Hui, FW; Krikun, E; Smith, AA | 1 |
Misra, AL; Pontani, RB; Vadlamani, NL | 1 |
D'Mello, GD; Pilcher, CW; Stolerman, IP | 1 |
Brine, GA; Carroll, FI; Cone, EJ; Darwin, WD; Gorodetzky, CW; Welch, CD | 1 |
Blumberg, H; Ikeda, C | 1 |
Black, R; Hersch, RG; Lewis, DC; Mayer, J | 1 |
Järbe, TU | 1 |
Bondeson, VC; Brine, DR; Brine, GA; Carroll, FI; Welch, CD | 1 |
Brotman, R; Remine, DC; Suffet, F; Taleporos, E | 1 |
Brahen, LS; Capone, T; Heller, RC; Landy, HJ; Lewis, MJ; Linden, SL | 1 |
Charuvastra, VC; Jarvik, ME; Sideroff, SI | 1 |
Erickson, CK; Harris, RA | 1 |
Blatnick, RA; Lieberman, MM; Pace, NL; Parrish, RG; Wong, KC | 1 |
Charuvastra, VC; Gritz, ER; Jarvik, ME; Schlesinger, J; Shiffman, SM | 1 |
Landsberg, R; Taintor, Z; Wicks, N | 1 |
Howes, JF; Schwope, AD; Wise, DL | 3 |
Greenstein, R; Hanna, N; Mintz, J; O'Brien, C; Woody, G | 1 |
Arias, R; Callahan, E; Glazer, M; McCleave, B; Rawson, R | 1 |
Bradford, A; Dorrier, C; Golondzowski, O; Hurley, F | 1 |
Kaim, SC | 1 |
Gerwirtz, D; Hurzeler, M; Kleber, H | 1 |
Curran, S; Savage, C | 1 |
Blakis, M; Haas, N; Holmes, E; Ling, W; Litaker, M | 1 |
Keegan, J; Lavenduski, C; Schooff, K | 1 |
Crawford, J; De Gracia, C; Nelkupa, JV; Parwatikar, S | 1 |
Cooperstein, J; Harris, M; Hough, G; Kauders, F; Resnick, R; Thomas, M | 1 |
Brahen, L; Capone, T; Wiechert, V | 1 |
Black, R; Hersch, R; Lewis, D; Mayer, J | 1 |
Bathala, MS; Bhat, HB; Frank, SG; Ludden, TM; Malspeis, L; Morrison, BE; Reuning, RH; Sokoloski, TD | 1 |
Baggot, JD; Frank, SG; Ludden, TM; Malspeis, L; Reuning, RH; Sokoloski, TD | 1 |
Gehrmann, JE; Killam, KF | 1 |
Colombel, MC; Jacob, J; Tremblay, E | 1 |
Bathala, MS; Feller, DR; Ludden, TM; Malspeis, L; Morrison, BE; Reuning, RH | 1 |
Braude, MC; Morrison, JM | 1 |
Holtzman, SG; Shannon, HE | 1 |
Frank, S; Malspeis, L; Notari, RE; Reuning, RH | 1 |
Brocco, MJ; Killam, KF; Robinson, CA | 1 |
Bell, JA; Martin, WR | 1 |
Kestenbaum, RS; Poole, D; Resnick, RB; Washton, A | 1 |
Hollister, LE; Kasper, P; Schwin, RL | 1 |
Bhat, HB; Burce, GL; Sokoloski, T | 1 |
Hanson, RN; Jiang, JB; Portoghese, PS; Takemori, AE | 1 |
Kogan, MJ; Mule, SJ; Verebey, K | 1 |
Brahen, LS; Capone, T; Desiderio, D; Wiechert, V | 1 |
Gallant, DM; Mielke, DH | 1 |
Cash, C; King, LJ; Minnema, KH | 1 |
Bläsig, J; Herz, A; Höllt, V; Paschelke, G | 1 |
Ary, M; Lomax, P | 1 |
Mulé, SJ; Resnick, RB; Verebey, K; Volavka, J | 1 |
Foldes, FF; Knoll, J; Rich, J; Vizi, ES | 1 |
Kalkwarf, DR; Sullivan, MF | 1 |
Jhamandas, K; Sutak, M | 2 |
Malspeis, L; Sams, RA | 1 |
Brine, GA; Carroll, FI; Hart, CK; Kotchmar, DJ; Moreland, CG; Praskash, D | 1 |
Berkowitz, BA; Finck, AD; Ngai, SH | 1 |
Geller, I; Hartmann, RJ; Ross, D | 1 |
McNamee, HB; Meyer, RE; Mirin, SM | 1 |
Freedman, AM; Kestenbaum, RS; Resnick, RB; Volavka, J | 1 |
Amico, L; Landsberg, R; Plumb, M; Taintor, Z; Wicks, N | 1 |
Chen, RC; Ho, AK | 1 |
Aronoff, M; Hough, G; Kauders, F; Kestenbaum, R; Lonborg, G; Resnick, R; Washton, A | 1 |
Chedekel, MA; Mule, SJ; Rosenthal, D; Verebely, K | 1 |
Fishman, J; Hahn, EF; Norton, BI | 1 |
Dimaio, J; Nogrady, T | 1 |
Cicero, TJ; Meyer, ER; Michael, H; Wilcox, CE | 1 |
Greenstein, RA; Mintz, J; O'Brien, CP; Woody, GE | 1 |
Lewis, DC | 1 |
Schecter, A | 2 |
Kauders, F; Schecter, A | 1 |
Brahen, LS | 1 |
Kalkward, DR; Sullivan, MF | 1 |
Arnold, DL; Granchelli, FE; Nelsen, L; Sheth, SG; Sidman, KR; Steber, WD; Strong, P | 1 |
Thies, C | 1 |
DePace, A; Kogan, MJ; Mulé, SJ; Verebey, K | 1 |
Calesnick, B | 1 |
Chen, RP; Fishman, J; Gray, MI; Hahn, EF; Heilman, RD | 1 |
Berggren, A; Rubenson, A; Sillén, U | 1 |
Bourgoin, S; Cesselin, F; Collin, E; Ferhat, L; Hamon, M; Mantelet, S; Mauborgne, A | 1 |
Di Giulio, AM; Donadoni, ML; Finco, C; Germani, E; Gorio, A; Malosio, ML; Mantegazza, P; Tenconi, B | 1 |
al-Rodhan, NR; Kelly, PJ; Yaksh, TL | 1 |
Guillaumet, G; Jabbouri, S; Lazar, S; Maunier, JC; Noël-Hocquet, S; Ropars, C | 1 |
Benzel, EC; Fowler, MR; Khare, V | 1 |
Pinnock, RD | 2 |
Bourgoin, S; Cesselin, F; Collin, E; Ferhat, L; Hamon, M | 1 |
Robinson, SR; Smotherman, WP | 1 |
Broccardo, M; Improta, G | 2 |
Kamei, J; Kasuya, Y; Kawashima, N | 1 |
Holtzman, SG; Jones, DN | 1 |
Kamei, J; Kasuya, Y; Kawashima, N; Ohhashi, Y | 1 |
Dickenson, AH; Kalso, EA; McQuay, HJ; Sullivan, AF | 1 |
Dewey, WL; Smith, FL | 2 |
Barg, J; Belcheva, MM; Chuang, DM; Coscia, CJ; Gao, XM; Gloeckner, C | 1 |
Crook, TJ; Hill, RG; Kitchen, I | 1 |
Riley, AL; Smurthwaite, ST | 2 |
Bergasa, NV; Jones, EA | 1 |
Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Manda, S | 1 |
Leyton, M; Stewart, J | 1 |
Bansinath, M; Puig, MM; Tang, CK; Turndorf, H; Warner, W | 1 |
Caudle, RM; Chavkin, C; Wagner, JJ | 1 |
Fujimoto, JM; Holmes, BB | 2 |
Kastin, AJ; Kersh, D; Wyatt, A; Zadina, JE | 1 |
Griffin, IJ; Jackson, HC; Nutt, DJ | 1 |
Katafuchi, T; Koizumi, K; Nagatomo, I | 1 |
Larson, AA; Mousseau, DD; Sun, X | 1 |
Kleber, HD; Kosten, TR; Morgan, C | 1 |
Barney, CC; Morrison, CM; Renkema, LA; Vergoth, C | 1 |
Fournié-Zaluski, MC; Noble, F; Roques, BP; Turcaud, S | 1 |
de Zwaan, M; Mitchell, JE | 1 |
Melzack, R; Plamondon, H; Vaccarino, AL | 1 |
Ho, IK; Hoskins, B; Jaw, SP; Makimura, M; Oh, KW | 2 |
Geter, B; Kautz, MA; Riley, AL; Smurthwaite, ST | 1 |
Holtzman, SG; Paronis, CA | 1 |
Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mantelet, S | 1 |
Carboni, E; Di Chiara, G; Garau, L; Longoni, R; Melchiorri, P; Mulas, A; Spina, L | 1 |
Jackson, HC; Nutt, DJ | 1 |
Calenco-Choukroun, G; Daugé, V; Féger, J; Gacel, G; Roques, BP | 1 |
Chalmers, J; Drolet, G; Morilak, DA | 1 |
Isayama, T; McLaughlin, PJ; Zagon, IS | 1 |
Aleman, DO; Bak, TH; Carr, KD; Simon, EJ | 1 |
Kaneto, H; Kawasaki, K; Kobayashi, Y; Maeda, M; Shimokawa, K; Taguchi, T; Takahashi, M; Tokuyama, S; Watanabe, J; Yamamoto, Y | 1 |
Jang, Y; Yoburn, BC | 1 |
Botschev, C; Müller, N | 1 |
Bilotta, JM; Brackeen, MF; Feldman, PL; James, MK; Leighton, HJ; Schuster, SV | 1 |
Jessop, JJ; Taplits, MS | 1 |
Lu, CL; Shaikh, MB; Siegel, A | 1 |
Angelucci, F; Negri, L; Noviello, V | 1 |
Baumann, MH; Rabii, J | 1 |
Furuya, Y; Kaneko, T; Nakazawa, T; Yamatsu, K | 1 |
Shiotsu, G; Stein, L; Stevens, KE | 1 |
Gannon, RL; Terrian, DM | 1 |
Godin, C; Henry, JL; Rochford, J | 1 |
Duckles, SP; Li, YJ | 1 |
Bourgoin, S; Cesselin, F; Chantrel, D; Collin, E; Hamon, M; Mauborgne, A | 1 |
Amao, H; Aoki, S; Hokao, R; Saito, TR; Sugiyama, M; Takahashi, KW; Wakafuji, Y | 1 |
Bansinath, M; Goldfrank, LR; Shukla, VK; Turndorf, H | 1 |
Mahayni, H; Minor, JR | 1 |
Burks, TF; Davis, TP; Greene, DL; Hersh, LB; Hruby, VJ; Kramer, TH; Sharma, SD; Weber, SJ; Yamamura, HI | 1 |
Firman, JD; Volmert, RF | 1 |
Ayres, EA; Burks, TF; Fang, S; Hruby, VJ; Kramer, TH; Parkhurst, DN | 1 |
Fletcher, PJ | 1 |
Cappell, H; Lê, AD; Poulos, CX; Walker, MJ | 1 |
Pasternak, GW; Paul, D; Pick, CG | 1 |
Casati, O; De Filippi, G; Foresti, V; Scolari, N; Zubani, R | 1 |
Gold, MS; Liebeskind, JC; Morgan, MM; Stein, C | 1 |
Jacoby, HI; Martinez, RP; Raffa, RB; Schupsky, JJ | 1 |
Coen, KM; Corrigall, WA | 1 |
Bossut, DF; Huang, ZS; Mayer, DJ; Sun, SL | 1 |
Bossut, DF; Mayer, DJ | 1 |
Armario, A; Garvey, JS; Giralt, M; Hidalgo, J | 1 |
Lopez, J; Naujokat, P; Toledo-Pereyra, LH; Walters, W; Xavier, R | 2 |
Kirkham, TC | 1 |
Kaneto, H; Takahashi, M; Watanabe, J | 1 |
Hoffmann, P; Skarphedinsson, JO; Thorén, P | 1 |
Koehler, E; McLemore, GL; Rosella-Dampman, LM; Summy-Long, JY | 1 |
Kromer, W | 3 |
Brasch, H; Kaschube, M | 1 |
Lenz, K; Loimer, N; Presslich, O; Schmid, R | 1 |
Bilsky, EJ; Marglin, SH; Reid, LD | 1 |
Leander, JD; Mayer-Valkanover, K; Nussbaumer, C; Schmidhammer, H; Schmidt, C; Schoepp, DD; Schratz, A; Walla-Kugler, M | 1 |
Misawa, M; Suzuki, T | 1 |
Fukagawa, Y; Misawa, M; Nagase, H; Suzuki, T | 2 |
Bodnar, RJ; Islam, AK | 1 |
de Costa, BR; France, CP; Jacobson, AE; Rice, KC; Woods, JH | 1 |
Ling, W; Wesson, DR | 2 |
Członkowski, A; Herz, A; Parsons, CG; Stein, C | 1 |
Heijna, MH; Hogenboom, F; Mulder, AH; Padt, M; Portoghese, PS; Schoffelmeer, AN | 1 |
Song, ZH; Takemori, AE | 1 |
Fuentes, JA; Iglesias, T; Jiménez, I | 1 |
Leander, JD; Zimmerman, DM | 1 |
Herz, A; Parsons, CG | 1 |
Balfour, HH; Gekker, G; Peterson, PK; Portoghese, PS; Sannerud, K; Sharp, BM | 1 |
Ben-Zvi, Z; Hurwitz, A; Looney, G; Sullins, M | 1 |
Delle, M; Hoffmann, P; Thorén, P | 1 |
Lutfy, K; Sierra, V; Yoburn, BC | 1 |
Cowan, A; Murray, CW | 1 |
Fleshner, M; Thurston, CL; Watkins, LR | 1 |
Kamei, J; Kasuya, Y; Tanihara, H | 1 |
Sinclair, JD | 1 |
Charney, DS; Kleber, HD; Kosten, TR; Krystal, JH; Morgan, CH; Price, LH | 2 |
Canli, T; Cook, RG; Miczek, KA | 1 |
Goldberg, SR; Katz, JL; Schindler, CW; Su, TP; Wu, XZ | 1 |
Angel, L; Appelmans, N; Gioannini, TL; Koolpe, GA; Nelson, WL; Simon, EJ | 1 |
Archer, S; Corbett, AD; Kosterlitz, HW; McKnight, AT; Paterson, SJ; Seyed-Mozaffari, A; Ward, S | 1 |
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW | 1 |
Einarsson, M; Koman, A; Terenius, L | 1 |
Cherubini, E; North, RA; Tokimasa, T | 1 |
Sandman, CA | 1 |
Cheng, SW; North, WG; O'Connor, EF | 1 |
Murray, MJ; Offord, KP; Yaksh, TL | 1 |
Melzack, R; Tasker, RAR; Vaccarino, AL | 1 |
Kosenkova, NS; Poshivalov, VP | 1 |
Reid, RL; Vanvugt, DA; Webb, MY | 2 |
Calcagnetti, DJ; Fanselow, MS; Helmstetter, FJ | 1 |
Buckingham, JC; Cover, PO | 1 |
Belluzzi, JD; Stein, L; Trujillo, KA | 2 |
Kanda, A; Kimura, T; Koyanagawa, H; Musha, T; Satoh, S | 1 |
France, CP; Morse, WH | 1 |
Fiserová, M; Metys, J | 1 |
Gurll, NJ; Holaday, JW; Lechner, RB; Reynolds, DG | 1 |
Bak, TH; Carr, KD; Portoghese, PS; Simon, EJ | 1 |
Heyman, JS; Jiang, Q; Mosberg, HI; Porreca, F; Rothman, RB | 1 |
Ahmed, MS; Quarles, C; Schoof, T; Zhou, DH | 1 |
Evans, RG; Ludbrook, J; Van Leeuwen, AF | 1 |
Huidobro-Toro, JP; Li, CH; Valenzuela, R | 1 |
Bals-Kubik, R; Herz, A; Shippenberg, TS | 1 |
Candeletti, S; Cavicchini, E; Ferri, S; Spampinato, S | 1 |
Fujimoto, JM; Rady, JJ | 2 |
Albuquerque, EX; Madsen, BW | 1 |
Abdelhamid, EM; Archer, S; Koolpe, GA; Michael, J; Michael, M; Nelson, WL; Simon, EJ | 1 |
Chaumont, AJ; Kintz, P; Lugnier, AA; Mangin, P | 1 |
Barsan, WG; Bartlett, R; Bryan, C; Buncher, R; Danzl, DF; Ling, LJ; Seger, D | 1 |
Barrett, RP; Feinstein, C; Hole, WT | 1 |
Bardin, CW; Belhadj, H; de Besi, L; Thau, RB | 1 |
Castellano, C; Introini-Collison, IB; McGaugh, JL; Pavone, F | 1 |
DiBona, GF; Jones, SY; Kapusta, DR | 1 |
Field, EA; Kuhn, CM | 2 |
Gentle, MJ; Savory, CJ; Yeomans, MR | 1 |
Dunlap, CE; Rose, JC; Valego, NK | 1 |
Kotlińska, J; Langwiński, R | 1 |
Pasternak, GW; Recht, LD | 1 |
Liu-Chen, LY; Phillips, CA | 1 |
Kunos, G; Mosqueda-Garcia, R | 1 |
Bykov, V; Holaday, JW; Jacobson, AE; Lessor, RA; McLean, S; Rice, KC; Rothman, RB | 1 |
Duax, WL; Hua, DH; Kolb, VM | 1 |
Almeida, OF; Herz, A; Nikolarakis, KE; Webley, GE | 1 |
Bykov, V; Holaday, JW; Jacobson, AE; Long, JB; Rice, KC; Rothman, RB | 1 |
Landymore, KM; Wilkinson, M | 1 |
Frischknecht, HR; Siegfried, B | 1 |
Hayes, AG; Sheehan, MJ; Tyers, MB | 1 |
Di Chiara, G; Imperato, A | 1 |
Katoh, M; Kimura, T; Satoh, S | 1 |
Holtzman, SG | 3 |
Baskin, DS; Hosobuchi, Y; Kuroda, H; Lee, NM | 1 |
Baron, SA; Gintzler, AR; Testa, FM | 1 |
Martin, WR; Wettstein, JG | 1 |
O'Neill, KA; Valentino, D | 1 |
Bloom, FE; Chavkin, C | 1 |
Ding, XZ; Fan, SG; Han, JS | 1 |
Lipkowski, AW; Portoghese, PS; Takemori, AE | 1 |
McLean, S; Rothman, RB | 1 |
Laorden, ML; Miralles, FS; Puig, MM | 1 |
Egdahl, RH; Gerstein, L; Grasberger, R; McIntosh, TK; Palter, M; Vezina, R; Yeston, N | 1 |
Eskay, R; Kunos, G; Mosqueda-Garcia, R; Palkovits, M; Zamir, N | 1 |
Bardin, CW; Boitani, C; Chen, CL; Gerendai, I; Margioris, AN; Morris, PL | 1 |
de Jong, W; van Giersbergen, PL | 1 |
Gallagher, M | 2 |
Bedu, M; Caillaud, D; Coudert, J; Molina, C | 1 |
Koenig, JI; Krulich, L; Moss, RL; Wiesner, JB | 1 |
Gaspari, J; Kleber, HD; Kosten, TR; Topazian, M | 1 |
Gardner, EL; Tempel, A; Zukin, RS | 2 |
Fries, DS; Larson, DL; Portoghese, PS; Takemori, AE; Ward, SJ | 1 |
Dray, A; Nunan, L; Wire, W | 1 |
Nawiesniak, E; Schenk, S | 1 |
Hahn, EF | 2 |
Hayes, AG; Skingle, M; Tyers, MB | 1 |
Kameyama, T; Ukai, M | 1 |
Cho, TM; Nozaki, M | 1 |
Eisenberg, RM | 4 |
Cohen, AH; Goodman, RR; Inturrisi, CE; Pasternak, GW; Yoburn, BC | 1 |
Bolger, G; Michel, ME; Weissman, BA | 1 |
Holaday, JW; Robles, L; Tortella, FC | 1 |
Fishman, J; Hahn, EF | 1 |
Faris, PL; Komisaruk, BR; Mayer, AD; Rosenblatt, JS | 1 |
Crowley, TJ; Macdonald, M; Wagner, JE; Zerbe, G | 1 |
Corbett, AD; Kostelitz, HW; McKnight, AT; Paterson, SJ; Robson, LE | 1 |
Bennett, JM; Burke, TR; Channing, MA; Eckelman, WC; Rice, KC | 1 |
Hayes, AG; Stewart, BR | 1 |
Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
Laubie, M; Schmitt, H | 1 |
Cabib, S; Oliverio, A; Puglisi-Allegra, S | 1 |
Liu-Chen, LY; Nickolson, VJ; Tam, SW | 1 |
Greenberg, AH; Kraut, RP | 1 |
Tempel, A; Zukin, RS | 1 |
Mayer, DJ; Watkins, LR | 1 |
James, DW; LoPresti, D; Ward, SJ | 1 |
Blank, MS; Daugherty, DT; Mann, DR; Murphy, JR; Sridiran, R | 1 |
Liu-Chen, LY; Tam, SW | 1 |
Clark, MJ; Levenson, SD; Medzihradsky, F | 1 |
Gilbert, PE; Jasinski, DR; Martin, CD; Martin, WR | 1 |
Mosberg, HI; Robles, L; Tortella, FC | 1 |
Burke, TR; Ostrowski, NL; Pert, A; Pert, CB; Rice, KC | 1 |
Panksepp, J; Sahley, TL | 1 |
Cavicchini, E; Ferri, S; Murari, G; Romualdi, P; Speroni, E | 1 |
Beck, CA; Reents, SB | 1 |
Chapman, RW; Mauser, PJ | 1 |
Altman, DG; Barrowcliffe, MP; Jones, JG; Jordan, C; Konieczko, KM | 1 |
Cappell, H; Greeley, JD; Lê, AD; Poulos, CX | 1 |
Lee, YS; Liu, XL; Mok, CP; Wong, TM | 1 |
Zagon, IS | 1 |
Bruzzone, ME; Marusic, ET | 1 |
Dixon, R; Simpkins, JW; Smulkowski, M; Tuttle, R | 1 |
Fishman, J; Lustig, RH; Pfaff, DW | 1 |
France, CP; Woods, JH | 3 |
Kramer, P; Meijs-Roelofs, HM | 1 |
Ikebuchi, H; Kawanishi, T; Nagamatsu, K; Ohno, Y; Takanaka, A; Terao, T | 1 |
Bhargava, HN; Ramarao, P | 1 |
Frischknecht, HR; Riggio, G; Siegfried, B; Waser, PG | 2 |
Stevens, CW; Yaksh, TL | 1 |
Bernstein, GA; Hughes, JR; Mitchell, JE; Thompson, T | 1 |
Frey, HH | 1 |
Haddad, GG; Jeng, HJ; Lai, TL | 1 |
Bryant, HU; Si, EC; Yim, GK | 1 |
Fanselow, MS | 1 |
Maier, SF | 1 |
Bittle, JB; Givens, JR; Howes, JF; Karas, JG; Kitabchi, AE; Kurtz, BR; Mitchell, JA | 1 |
Blundell, JE; Kirkham, TC | 2 |
Kavaliers, M | 1 |
Iakimova, K | 1 |
Kouchich, FJ; Panek, RW; Quock, RM; Rosenthal, MA | 1 |
Denbow, DM; McCormack, JF | 1 |
Bohus, B; Cottrell, GA | 1 |
Arteau, C; Fujimoto, JM; Roerig, SC | 1 |
Fanselow, MS; Helmstetter, FJ | 1 |
Cherkin, A; Flood, JF; Morley, JE | 1 |
Florentino, A; Fuentes, JA; Jiménez, I; Naranjo, JR; Urdín, MC | 1 |
Bardin, CW; Gerendai, I; Gunsalus, GL; Shaha, C | 1 |
Borrell, J; Fuentes, JA; Naranjo, JR; Urdín, MC | 1 |
Baker, TB; Dahl, JL; Silva, BW; Tiffany, ST | 1 |
Gowans, GC; Grilly, DM | 1 |
Chou, CK; Guy, AW; Horita, A; Lai, H | 1 |
Eikelboom, R | 1 |
Court, MH; Dixon, R; Dodman, NH; Shuster, L | 1 |
de Feo, G; Mazzanti, G; Piccinelli, D | 2 |
Bardin, CW; Hahn, EF; Limonta, P; Thau, RB | 1 |
Fanselow, MS; Lester, LS | 1 |
Harris, LS; May, EL | 1 |
Ferreira, SH; Follenfant, RL; Smith, TW | 1 |
Bracco, EF; Hashim, SA; Kissileff, HR; Maggio, CA; Pfohl, DN; Presta, E; Vasselli, JR | 1 |
Carino, MA; Horita, A; Pae, YS | 1 |
Baskin, DS; Grevel, JC; Hosobuchi, Y | 1 |
Cowan, A; Gmerek, DE; Woods, JH | 1 |
Allen, DL; Luine, VN; Renner, KJ | 1 |
Garrett, ER | 1 |
Beckman, AL; Llados-Eckman, C | 1 |
Lowy, MT; Sangiah, S; Yim, GK | 1 |
McLaughlin, PJ; Zagon, IS | 9 |
Pittock, F; Randall, J; Rodgers, RJ | 1 |
Moerschbaecher, JM; Thompson, DM; Winsauer, PJ | 1 |
Dufau, ML; Kitchin, JD; Perez-Palacios, G; Rogol, AD; Stumpf, P; Veldhuis, JD | 1 |
Fries, DS; Kouchich, FJ; Quock, RM; Vaughn, LK | 1 |
Horita, A; Lai, H; Pae, YS | 1 |
Aliyu, SU; Badawy, AA | 1 |
Girardot, MN; Holloway, FA | 2 |
Fries, DS; Kouchich, FJ; Quock, RM | 1 |
Cowan, A; Gmerek, DE; Ryan, JP | 1 |
Dykstra, LA | 1 |
Gmerek, DE; Woods, JH | 1 |
Asdourian, D; Geula, C | 1 |
Adams, JU; France, CP; Woods, JH | 1 |
Michael, RP; Schaefer, GJ | 2 |
Bostock, E; Gallagher, M; King, R | 1 |
Levine, AS; Morley, JE; Plotka, ED; Seal, US | 1 |
Friedman, JG; Grossman, DJ; Schecter, AJ | 1 |
Jacobson, AE; Rice, KC; Sadée, W; Yu, VC | 1 |
Atkinson, RL | 1 |
Gold, MS; Pottash, AC; Washton, AM | 1 |
Ginzburg, HM; Glass, WJ | 1 |
Pert, CB; Rothman, RB; Schumacher, UK | 1 |
Larson, DL; Portoghese, PS; Sayre, LM; Takemori, AE | 1 |
Cicero, TJ; Meyer, ER; Owens, DP; Schmoeker, PF | 1 |
del Río, J; Fernández-Tomé, MP; González, Y; Sánchez-Franco, F | 1 |
Briski, K; Meites, J; Quigley, K | 1 |
North, RA; Williams, JT | 1 |
Holaday, JW; Tortella, FC | 1 |
Galizio, M; Smaltz, SC; Spencer, BA | 1 |
Rawson, RA; Resnick, RB; Tennant, FS; Washton, AM | 2 |
Bernardini, GL; Clark, WG; Pang, IH | 1 |
Bennett, JM; Burke, TR; Channing, MA; Danks, JA; Eckelman, WC; Larson, SM; Pert, CB; Rice, KC | 1 |
Nikolarakis, KE; Pfeiffer, A; Pfeiffer, DG | 1 |
Cooper, KE; Thornhill, JA; Veale, WL | 1 |
Harris, RA | 1 |
Dickinson, SL; Longman, DA; Slater, P | 1 |
Annitto, W; Gold, MS; Pottash, AL; Sternbach, HA | 1 |
Portoghese, PS; Takemori, AE; Ward, SJ | 2 |
Gintautas, JG; Kraynack, BJ | 1 |
Cerdeño Impuesto, V | 1 |
Freye, E; Hartung, E; Kaliebe, S | 1 |
Burks, TF; Galligan, JJ | 1 |
Huidobro-Toro, JP; Way, EL; Yoshimura, K | 1 |
Chavkin, C; Goldstein, A; James, IF | 1 |
Takemori, AE; Ward, SJ | 2 |
Drum, MA; Harrigan, SE; Macgregor, TR; Reuning, RH; Wiley, JN | 1 |
Chavkin, C; Cox, BM | 1 |
Hameroff, SR | 1 |
Fischli, W; Goldstein, A; James, IF | 1 |
Herz, A; Schulz, R; Wüster, M | 1 |
Bakharev, VD; Tikhomirov, SM | 1 |
Lawson, EE; Long, WA | 1 |
Billington, CJ; Gosnell, BA; Levine, AS; Morley, JE | 1 |
Jackson, HC; Sewell, RD | 1 |
Armstrong, MJ; Larson, AA | 1 |
Carroll-Buatti, M; Hahn, EF; Pasternak, GW | 1 |
Goldstein, DJ; Keiser, HR | 1 |
Giles, T; Merz, H; Sander, G | 1 |
Angel, L; Gioannini, TL; Koolpe, GA; Nelson, WL; Simon, EJ | 1 |
Bell, RD; Cicero, TJ; Meyer, ER; Wilcox, CE | 1 |
Simon, EJ; Smith, JR | 1 |
Clemens, JA; Shaar, CJ | 1 |
Cheng, RS; Pomeranz, BH | 1 |
Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD | 1 |
Chance, WT | 1 |
Hahnenberger, RW | 1 |
Smith, AA; Wassef, NM | 1 |
Barchas, JD; Davies, S; Grau, JW; Jackson, RL; Madden, J; Maier, SF; Morrison, DH; Moye, T | 1 |
Concannon, JT; Maloney, R; McKelvey, J; Riccio, DC | 1 |
Herling, S; Medzihradsky, F; Merz, H; Valentino, RJ; Woods, JH | 1 |
Larson, DL; Portoghese, PS; Takemori, AE | 1 |
Amir, S; Simantov, R | 1 |
Carrasco, MA; Dias, RD; Elisabetsky, E; Izquierdo, I; Perry, ML; Souza, DO | 1 |
Frenk, H; Urca, G; Yitzhaky, J | 1 |
Ayhan, IH; Portoghese, PS; Takemori, AE; Tulunay, FC | 1 |
Byrne, WL; Codd, EE | 1 |
Misra, AL | 1 |
Kosterlitz, HW; Paterson, SJ; Robson, LE | 1 |
Bohus, B; Csontos, KM; de Rotte, GA; de Wied, D; Gispen, WH; Greven, HM; Nijkamp, FP; Opmeer, FA; van Ree, JM; van Wimersma Greidanus, TB; Witter, A | 1 |
Blume, AJ; Fantozzi, R; Mullikin-Kilpatrick, D | 1 |
Clark, WG | 1 |
Luciano, M; Pert, CB; Recant, L; Voyles, NR | 1 |
Childers, SR; Dunn, AJ; Kramarcy, NR; Villiger, JW | 1 |
Volavka, J | 1 |
Buchweitz, E; Grandison, L; Weiss, HR | 1 |
Gurll, NJ; Lechner, R; Reynolds, DG; Vargish, T | 1 |
Oishi, R; Takemori, AE | 1 |
Castellano, C; Puglisi-Allegra, S | 1 |
Messing, RB; Portoghese, PS; Sparber, SB; Takemori, AE | 1 |
Fabre-Nys, C; Keverne, EB; Meller, RE | 1 |
Harris, RA; Snell, D | 2 |
Pasternak, GW | 1 |
De Wied, D; Fekete, M | 1 |
Gioannini, T; Gorissen, H; Maryanoff, BE; Simon, EJ | 1 |
Extein, I; Gold, MS; Kleber, HD; Martin, D; Pottash, AC | 1 |
Fitz-Syage, ML; Gardner, EL; Gintzler, AR; Sugarman, JR; Zukin, RS; Zukin, SR | 1 |
Cools, AR; Megens, AA | 1 |
Schadt, JC; York, DH | 1 |
Ashcraft, LJ; Drugan, RC; Grau, JW; Hyson, RL; Maier, SF | 1 |
Cooper, SJ | 5 |
Blume, AJ; Larsen, NE; Mullikin-Kilpatrick, D | 1 |
Hamann, SR; Myers, RD; Oeltgen, PR; Randall, DC; Spurrier, WA; Walsh, JW | 1 |
Brown, DR; Holtzman, SG; Locke, KW | 1 |
Retz, KC; Steele, WJ | 1 |
Bohus, B; De Wied, D; Drago, F; Fekete, M; Van Ree, JM; Wiegant, VM | 1 |
Herling, S | 3 |
Bersh, PJ; Margules, DL; Walker, J; Whitehouse, WG | 1 |
Fries, DS; Larson, DL; Portoghese, PS; Sayre, LM; Takemori, AE | 1 |
Grevel, J; Sadée, W | 1 |
Vaupel, DB | 1 |
Frantz, AG; Kreek, MJ; Ragavan, VV; Wardlaw, SL | 1 |
Amir, S | 3 |
Bardo, MT; Bhatnagar, RK; Gebhart, GF | 1 |
Martin, WR; McNicholas, LF | 1 |
Belenky, GL; Gelinas-Sorell, D; Holaday, JW; Kenner, JR | 1 |
D'Amato, RJ; Holaday, JW | 1 |
Herman, BH; Holtzman, SG | 1 |
Bowen, WD; Pert, CB; Rothman, RB; Schumacher, UK | 1 |
Cowan, A; Holaday, JW; Robles, LE; Tortella, FC | 1 |
Amit, Z; Blair, R; Holmes, L; Ng Cheong Ton, MJ | 1 |
Gioannini, TL; Hiller, JM; Howard, A; Simon, EJ | 1 |
Kizer, JS; Lipton, MA; McCubbin, JA | 1 |
Koenig, JI; Krulich, L; Mayfield, MA; McCann, SM | 1 |
Childress, AR; Ehrman, RN; McLellan, AT; O'Brien, CP; Ternes, J | 1 |
Herling, S; Solomon, RE; Valentino, RJ; Woods, JH | 1 |
Dackis, CA; Gold, MS; Washton, AM | 1 |
Carr, KD | 1 |
Cooper, SJ; McGivern, H | 1 |
Hoffman, PL; Kiianmaa, K; Tabakoff, B | 1 |
Evans, BD; Greenstein, RA; McLellan, AT; O'Brien, CP | 2 |
Messing, RB; Rigter, H; Rijk, H | 1 |
Ashcraft, SB; Downs, DA; Harrigan, SE; Liao, SH; Reuning, RH; Staubus, AE; Wiley, JN; Wise, DL | 1 |
Abbott, DH; Berman, M; Goy, RW; Holman, SD; Neff, DA | 1 |
Balmagiya, T; Gross, E; Marks-Kaufman, R | 1 |
Arndt, I; McLellan, AT; O'Brien, CP | 1 |
Rawson, RA; Tennant, FS | 1 |
Carino, MA; Fatherazi, S; Horita, A; Lai, H; Pae, YS | 1 |
Sonka, K | 1 |
Koek, W; Slangen, JL | 1 |
Rosenkrantz, H | 1 |
Lo, MW; Meyer, MC; Schary, WL; Straughn, AB; Whitney, CC | 1 |
Arndt, IC; Evans, B; Greenstein, RA; McLellan, AT; O'Brien, CP | 1 |
Kleber, HD; Kosten, TR | 2 |
Cohen, AJ; Mann, A; Rawson, RA; Tennant, FS | 1 |
Brahen, LS; Capone, T; Henderson, RK; Kordal, N | 1 |
Christian, MS | 1 |
Bigelow, GE; Sherman, MF; Singleton, EG | 1 |
Goldstein, A; Judson, BA | 1 |
Charney, DS; Galloway, MP; Heninger, GR; Kleber, HD; Murberg, M; Redmond, DE; Roth, RH | 1 |
Saunders, W; Thornhill, JA | 1 |
Barnett, G; Chiang, CN; Hollister, LE; Kishimoto, A | 1 |
Castellano, C; Filibeck, U; Pavone, F | 1 |
Asali, LA; Brown, KF | 1 |
Dixon, R; Hahn, E; Hsiao, J; Taaffe, W; Tuttle, R | 1 |
Greenstein, RA; Resnick, E; Resnick, RB | 1 |
Eldridge, FL; Klingler, LE; Millhorn, DE; Waldrop, TG; Wilson, BA | 1 |
Bodor, N; Katovich, MJ; Simpkins, JW; Song, IC; Tuttle, R | 1 |
Bardin, CW; Gerendai, I; Shaha, C; Thau, R | 1 |
Katz, RJ; Manik, CP | 1 |
Bohus, B; Cottrell, GA; Nyakas, C | 1 |
Borrell, J; Fuentes, JA; Naranjo, JR | 1 |
Wiesenfeld-Hallin, Z | 1 |
Amir, S; Harel, M | 2 |
Dresel, KM; Dyck, DG; Grant, D; Greenberg, AH; Pohajdak, B; Sandler, LS | 1 |
Baile, CA; McLaughlin, CL | 1 |
Beatty, WW | 1 |
Cooper, SJ; Holtzman, SG | 1 |
Ginzburg, HM | 1 |
Argentieri, TM; McArdle, JJ | 1 |
Carino, MA; Horita, A; Yamawaki, S | 1 |
Dixon, R; Hsiao, J | 1 |
Asali, LA; Brown, KF; Nation, RL | 1 |
Herling, S; Valentino, RJ; Woods, JH | 2 |
Anggård, E; Jones, AW; Neri, A | 1 |
Krystal, JH; Redmond, DE | 1 |
Brown, DR; Goldberg, LI; Robertson, MJ | 1 |
Burks, TF; Porreca, F | 1 |
Delander, GE; Takemori, AE | 1 |
Pivorun, EB; Tannenbaum, MG | 1 |
Bloom, FE; Ettenberg, A; Koob, GF; Pettit, HO | 1 |
Slater, P | 1 |
Derendorf, H; El-Din, A; El-Koussi, A; Garrett, ER | 1 |
Ortiz, E; Reyes, E; Saland, LC | 1 |
Shuster, L; Thompson, ML; Weiss, J | 1 |
Bell, RD; Cicero, TJ; Gerrity, M; Newman, KS; Schmoeker, PF | 1 |
Anderson, B; Koz, G; Volavka, J | 1 |
Altshuler, HL; Feinhandler, DA; Phillips, PE | 1 |
Resnick, RB; Stone-Washton, N; Washton, AM | 2 |
Brine, DR; Perez-Reyes, M; Wall, ME | 1 |
Verebey, K | 2 |
Licko, V | 1 |
Liao, SH; Reuning, RH; Staubus, AE | 1 |
Kincl, FA; Olsen, JL | 1 |
Ashcraft, SB; Morrison, BE; Reuning, RH | 1 |
Olsen, JL | 1 |
Archer, S | 1 |
Brine, DR; Wall, ME | 1 |
Perez-Reyes, M; Wall, ME | 1 |
Gerner, RH; Gitlin, MJ; Rosenblatt, M | 1 |
Domino, EF; Ruffing, DM | 1 |
Byrd, LD | 1 |
Critcher, EC; Lin, CI; Myers, RD; Patel, J | 1 |
Carr, KD; Simon, EJ | 1 |
Aroyewun, OO; Barr, GA | 1 |
Chee, O; Keil, LC; Rosella-Dampman, LM; Summy-Long, JY | 1 |
Mandel, P; Oliverio, A; Puglisi-Allegra, S | 1 |
Ban, T; Berney, S; Ragheb, M | 1 |
Carney, TM; Goldstein, A; Judson, BA | 1 |
Herling, S; Woods, JH; Young, AM | 1 |
Woods, JH; Young, AM | 1 |
Lowy, MT; Yim, GK | 2 |
Maas, CL | 1 |
Ellingboe, J; Kuehnle, JC; Mello, NK; Mendelson, JH; Veldhuis, JD | 1 |
Cochin, J; Miller, JM; Poulsen-Burke, J; Rosow, CE | 1 |
Berman, RF; Eggleton, CE; Stone, WS | 1 |
Erez, M; Portoghese, PS; Takemori, AE | 1 |
Bianchi, G; Fiocchi, R; Manara, L; Tavani, A | 1 |
Blumberg, H; Slovak, DM | 1 |
McCarthy, PS; Sanger, DJ | 1 |
Barnes, CD; Lang, IM; Lutherer, LO; Strahlendorf, HK; Strahlendorf, JC | 1 |
Braverman, P; Charney, DS; Heninger, GR; Kleber, HD; Murburg, M; Redmond, DE; Riordan, CE; Sternberg, DE | 1 |
Cicero, TJ; Meyer, ER; Schmoeker, PF | 1 |
Chance, WT; Finkelstein, JA; Fischer, JE; van Lammeren, FM | 1 |
Crowley, TJ; Hydinger-Macdonald, MJ; Mast, RT | 1 |
Fossom, LH; Sparber, SB | 1 |
Hughes, MJ; Lang, IM; McKown-Pulliam, R; Strahlendorf, HK; Strahlendorf, JC | 1 |
Malone, MH; Namba, MM; Quock, RM | 2 |
Bearden, LJ; Snead, OC | 1 |
Herbert, J; Keverne, EB; Meller, RE | 1 |
Bree, MP; Mello, NK; Mendelson, JH | 1 |
Bass, P; Goldberg, LI; Merz, H; Russell, J; Schuster, CR | 1 |
Altshuler, HL; Shippenberg, TS | 1 |
Schechter, MD | 1 |
Katz, RJ; Roth, KA; Schmaltz, K; Sibel, M | 1 |
Goldberg, DM; Goldberg, SR; Morse, WH | 1 |
Brown, DR; Holtzman, SG | 4 |
Deen, K; Keil, LC; Severs, WB; Summy-Long, JY | 1 |
Goldberg, SR; Kelleher, RT; Morse, WH; Spealman, RD | 1 |
Lucas, TS; Quock, RM | 1 |
Higuchi, T; Kawakami, M | 1 |
Apfelbaum, M; Mandenoff, A | 1 |
Johnson, JH; Mayer, DJ; Swajkoski, AR | 1 |
Boukhabza, D; Gillespie, HK; Hollister, LE; Johnson, K | 1 |
Barnes, CD; Lang, IM; Strahlendorf, HK; Strahlendorf, JC | 1 |
Advokat, C | 1 |
Anton, RF; Hogan, I; Jalali, B; Kleber, HD; Riordan, CE | 1 |
Ahmed, HH; Fanjul, LF; Meites, J; Ruiz de Galarreta, CM; Van Vugt, DA | 1 |
Coyle-Perkins, G; Grabowski, J; Greenstein, RA; Long, M; McLellan, AT; O'Brien, CP; Vittor, A; Woody, GE | 1 |
Goldstein, A; Himmelberger, DU; Judson, BA | 1 |
Ellingboe, J; Kuehnle, JC; Mendelson, JH | 1 |
Olds, ME; Williams, KN | 1 |
Ellingboe, J; Kuehnle, JC; Mello, NK; Mendelson, JH | 1 |
Kuehnle, JC; Mello, NK; Mendelson, JH; Sellers, MS | 1 |
Arias, R; Callahan, EJ; Glazer, M; Liberman, RP; McCleave, B; Rawson, RA | 1 |
Pilcher, CW | 1 |
Altshuler, HL; Applebaum, E; Shippenberg, TS | 1 |
Culpepper-Morgan, JA; Holt, PR; Kreek, MJ; LaRoche, D | 1 |
Laorden, ML; Llobell, F | 1 |
Crain, SM; Shen, KF | 2 |
Berzetei-Gurske, IP; DeCosta, BR; Pasternak, GW; Polgar, W; Toll, L; White, A | 1 |
Goettl, VM; Larson, AA | 1 |
Crain, SM | 1 |
Chen, L; Gu, Y; Huang, LY | 1 |
Goodman, M; Malmberg, AB; Ro, S; Schiller, P; Yaksh, TL | 1 |
Gates, CC; Haigh, JC | 1 |
Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M | 2 |
Bodnar, RJ; Cole, JL; Kirkham, TC; Leventhal, L | 1 |
Rault, B; Saiag, B; Shacoori, V | 1 |
Gamba, O; Gastaldi, M; Genazzani, AD; Genazzani, AR; Petraglia, F; Volpogni, C | 1 |
Han, JS; Jen, MF; Xue, JC; Yu, YX | 1 |
Billington, CJ; Briggs, J; Grace, MK; Kotz, CM; Levine, AS | 1 |
Bodnar, RJ; Bowen, WD; Cole, JL; Leventhal, L; Pasternak, GW | 1 |
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M; Saitoh, A; Suzuki, T | 1 |
Tripathi, A; Welch, SP | 1 |
Adler, MW; Bussiere, JL; Eisenstein, TK; Geller, EB; Meissler, JJ; Rogers, TJ | 1 |
Ulm, RR; Volpicelli, JR; Volpicelli, LA | 1 |
Bélisle, S; Bellabarba, D; Gallo-Payet, N; Lehoux, JG; Petit, A | 1 |
Bodnar, RJ; Glass, MJ; Koch, JE | 1 |
Diop, L; Junien, JL; Pascaud, X; Rivière, PJ | 1 |
Randić, M; Wang, RA | 1 |
Blommaert, A; Fournié-Zaluski, MC; Noble, F; Roques, BP | 1 |
Kuznetsov, A; Ma, GH; Miller, RJ; Philipson, LH | 1 |
Noble, F; Roques, BP | 1 |
Donatini, A; Ferri, S; Lesa, G; Romualdi, P | 1 |
Lewis, DV; Xie, CW | 1 |
Carpenter, JW; Leith, DE; Shaw, ML | 1 |
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T | 1 |
Aloyo, VJ; Pazdalski, PS | 1 |
Foss, JF; Moss, J; Yuan, CS | 1 |
Adams, JU; Li, S; Liu-Chen, LY; Yang, HH | 1 |
Briski, KP; Vogel, KL | 1 |
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M | 2 |
Elliott, J; Lambert, DG; Smart, D; Traynor, JR | 2 |
Thompson, DF; Welch, EB | 1 |
Bergsbaken, C; Law, PY | 1 |
Bodnar, RJ; Glass, MJ; Hahn, B; Joseph, A | 1 |
Dhawan, KN; Gupta, MB; Nath, C; Patnaik, GK | 1 |
Holtzman, S; White-Gbadebo, D | 1 |
Almeida, OF; Bartl, C; Shippenberg, TS; Spanagel, R | 1 |
Adler, MW; Eisenstein, TK; Guan, L; Rogers, TJ; Townsend, R | 1 |
Avidor-Reiss, T; Barg, J; Ezra, V; Levy, R; Matus-Leibovitch, N; Saya, D; Vogel, Z; Zippel, R | 1 |
Gillberg, C | 1 |
Planas, E; Pol, O; Puig, MM | 1 |
Bidlack, JM; Joseph, DB | 1 |
Búzás, B; Cox, BM; Izenwasser, S | 1 |
Goñalons, E; Jimenez, M; Martinez, V; Vergara, P | 1 |
Brent, PJ; Cantarell, PA; Chahl, LA; Kavanagh, C | 1 |
Aman, MG | 1 |
Connelly, CD; Martinez, RP; Porreca, F; Raffa, RB; Schupsky, JJ | 1 |
Chavkin, C; Terman, GW; Wagner, JJ | 1 |
Macdonald, RL; Moises, HC; Rusin, KI | 1 |
Freier, DO; Fuchs, BA | 1 |
Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A | 1 |
Cui, Y; Lee, T; Wang, LC | 1 |
Kwok, YN; McIntosh, C; Yago, V | 1 |
Noble, F; Roques, BP; Smadja, C | 1 |
Hitosugi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H | 1 |
Guy, AW; Horita, A; Lai, H | 1 |
Boersma, CJ; Pool, CW; Van Heerikhuize, JJ; Van Leeuwen, FW | 1 |
Bowen, WD; Miyamoto, Y; Portoghese, PS; Takemori, AE | 1 |
Bell, GI; Kong, H; Raynor, K; Reisine, T; Takeda, J; Yano, H | 1 |
Dassaud, M; Diop, L; Junien, JL; Pascaud, X; Rivière, PJ | 1 |
Randich, A; Robertson, JD; Willingham, T | 1 |
Glass, PS; Jhaveri, RM; Smith, LR | 1 |
Goodwin, GA; Molina, VA; Spear, LP | 1 |
Castellano, C; Introini-Collison, IB; McGaugh, JL | 1 |
Amin, HM; Camporesi, EM; Esposito, BF; Foss, JF; Roizen, MF; Sopchak, AM | 1 |
Lendvai, B; Sándor, A; Sándor, NT | 1 |
Kavaliers, M; Saucier, DM | 1 |
Carr, KD; Papadouka, V | 1 |
Akinbami, MA; Collins, DC; Mann, DR; Taylor, MF | 1 |
Holtzman, SG; White-Gbadebo, D | 1 |
Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
Cattaneo, I; Guilbaud, G; Kayser, V | 1 |
Colwell, DD; Kavaliers, M | 1 |
Bianchi, M; Panerai, AE | 1 |
Davis, T; Duttaroy, A; Shah, S; Yoburn, BC | 1 |
Bowen, WD; Holtzman, SG; Jones, DN; Portoghese, PS | 1 |
Casper, RF; Graves, GR; Kennedy, TG; Weick, RF | 1 |
Innes, DG; Kavaliers, M | 1 |
Caruso, A; Cucinelli, F; Fulghesu, AM; Lanzone, A; Mancuso, S | 1 |
Dewey, WL; Dombrowski, DS; Smith, FL; Welch, SP | 1 |
Cheng, PY; Decena, J; McCabe, S; Soong, Y; Szeto, HH; Wu, D | 1 |
Miyamoto, Y; Takemori, AE | 1 |
Miyamoto, Y; Portoghese, PS; Takemori, AE | 1 |
Bodnar, RJ; Koch, JE | 1 |
Nejat, RJ; Pasternak, GW; Pick, CG | 1 |
De Sarro, A; De Sarro, G; Masuda, Y; Sinopoli, S; Trimarchi, GR | 1 |
Bull, PM; Clarke, G; Douglas, AJ; MacMillan, SJ; McGrory, BG; Neumann, I; Russell, JA; Way, SA; Wright, DM | 1 |
Amico, MC; Morrone, LA; Romanelli, L; Valeri, P | 1 |
Kawabata, A; Takagi, H; Umeda, N | 1 |
Bianchi, M; Locatelli, L; Manfredi, B; Panerai, AE; Sacerdote, P; Veljic-Radulovic, J | 1 |
Welch, SP | 1 |
Bourgoin, S; Cesselin, F; Collin, E; Frechilla, D; Hamon, M; Le Bars, D; Pohl, M | 1 |
Henriksen, SJ; Koob, GF; Mattox, A; Negus, SS; Pasternak, GW; Portoghese, PS; Takemori, AE; Weinger, MB | 1 |
Plotsky, PM; Rivest, S; Rivier, C | 1 |
Tiseo, PJ; Yaksh, TL | 1 |
Chuluyan, HE; Saphier, D; Welch, JE | 1 |
Bonavera, JJ; Kalra, PS; Kalra, SP | 1 |
Adams, ML; Cicero, TJ; Forman, JB; Meyer, ER; Sewing, B | 1 |
Desmeules, JA; Gacel, G; Guilbaud, G; Kayser, V; Roques, BP | 1 |
Andres-Trelles, F; Baamonde, A; Hidalgo, A; Menendez, L | 1 |
Cutler, R; Fishbain, DA; Rosomoff, HL | 1 |
Desmeules, JA; Guilbaud, G; Kayser, V | 1 |
Kitchen, I; Muhammad, BY | 1 |
Cheng, PY; Decena, JA; McCabe, S; Soong, Y; Szeto, HH; Wu, D | 1 |
Alcaraz, C; Milanés, MV; Vargas, ML | 1 |
Beczkowska, IW; Bodnar, RJ; Bostock, ME; Koch, JE; Leibowitz, SF | 1 |
Koob, GF; Negus, SS; Pasternak, GW; Weinger, MB | 1 |
Carino, MA; Guy, AW; Horita, A; Lai, H | 1 |
Rust, M | 1 |
Cobbe, SM; Hicks, MN; Oldroyd, KG | 1 |
Chaudhry, H; Hofmann, P; Loimer, N | 1 |
Deakin, A; Leehey, DJ; Reid, RW | 1 |
Fleshner, M; Grisel, JE; Maier, SF; Watkins, LR | 1 |
Osifchin, E; Veng-Pedersen, P; Waters, SJ; Wilhelm, JA; Zakszewski, TB | 2 |
Apfel, SC; Dormia, C; Kessler, JA; Newel, M | 1 |
Coderre, TJ; Fundytus, ME; Schiller, PW; Shapiro, M; Weltrowska, G | 1 |
Hansson, P; Lundeberg, T; Yu, LC | 1 |
Adler, MW; Chen, XH; Geller, EB | 1 |
Cowan, A; Hunter, JC; Kovelowski, CJ; Lai, J; Malan, TP; Ossipov, MH; Porreca, F; Wheeler-Aceto, H | 1 |
Bigelow, GE; Eissenberg, T; Greenwald, MK; Johnson, RE; Liebson, IA; Stitzer, ML | 1 |
Mendez, M; Miranda, HF; Pinardi, G; Sierralta, F | 1 |
Borgbjerg, FM; Frigast, C; Madsen, JB | 1 |
Negri, L; Noviello, L; Noviello, V | 1 |
Iwatsubo, K; Kawabata, A; Takagi, H; Takaya, S | 1 |
Karasawa, F; Kitani, Y; Kuribara, H; Morita, T; Sato, T; Uchihashi, Y | 1 |
Chahl, LA; Herdegen, T; Leah, J; Lynch-Frame, AM; Trueman, L | 1 |
Funada, M; Schutz, CG; Shippenberg, TS | 1 |
Kamei, J; Morita, K; Nagase, H; Saitoh, A; Suzuki, T | 1 |
Chao, CC; Gekker, G; Hu, S; Molitor, TW; Peterson, PK; Sheng, WS | 1 |
Potter, DE; Wang, D | 1 |
Girre, A; Lemay, V; Rault, B; Saïag, B; Shacoori, V | 1 |
Anacardio, R; Attila, M; Bryant, SD; Capasso, A; Guerrini, R; Lazarus, LH; Salvadori, S; Sorrentino, L | 1 |
Grouhel, A; Wettstein, JG | 1 |
Honkanen, A; Hyytiä, P; Korpi, ER; Sarviharju, M; Vilamo, L; Wegelius, K | 1 |
Bless, EP; Kelley, AE; Swanson, CJ | 1 |
Gergen, KA; Kastin, AJ; Paul, D; Zadina, JE | 1 |
Balian, H; Liebeskind, JC; Mogil, JS; Sadowski, B; Sternberg, WF | 1 |
Fernández-Guasti, A; Rodríguez-Manzo, G | 1 |
Spanagel, R | 2 |
Casares, F; Liu, U; Stefano, GB | 1 |
Bodnar, RJ; Cole, JL; Leventhal, L | 1 |
Cook, CD; Morgan, D; Negus, SS; Picker, MJ | 1 |
Feng, J; Kendig, JJ | 1 |
Fields, HL; Roychowdhury, SM | 1 |
Ahtee, L; Piepponen, TP | 1 |
Miranda, HF; Naquira, D; Pinardi, G; Sierralta, F | 1 |
Bartter, T; Gooberman, LL | 1 |
Coimbra, NC; Eichenberger, GC; Gorchinski, RT; Maisonnette, S | 1 |
Duncan, MJ; Elde, RP; Gurwell, JA; Hauser, KF; Maderspach, K; Stiene-Martin, A | 1 |
Feuerstein, TJ; Gleichauf, O; Jackisch, R; Landwehrmeyer, GB; Peckys, D; Scheremet, R | 1 |
Mokha, SS; Wang, XM; Yan, JQ; Zhang, KM | 1 |
Bodnar, RJ; Leventhal, L | 1 |
Berger, SP; Broderick, PA; Hsu, K; Reid, MS; Souza, KH | 1 |
Fournié-Zaluski, MC; Fuentes, JA; Hernando, F; Roques, BP; Ruiz-Gayo, M | 1 |
Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ | 1 |
Mattheij, JA; Roozendaal, MM; Swarts, JJ; van Maanen, JC; Wiegant, VM | 1 |
Laorden, ML; Llobel, F | 1 |
Breivogel, CS; Childers, SR; Selley, DE | 1 |
Ho, ST; Lee, SC; Tao, PL; Wang, JJ | 1 |
Cervós-Navarro, J; Dey, PK; Nyberg, F; Sharma, HS; Westman, J | 1 |
Bombelli, R; Cosentino, M; Ferrari, M; Frigo, G; Giaroni, C; Lecchini, S; Marino, F; Rasini, E | 1 |
Khan, S; Smith, ME | 1 |
McLaughlin, PJ; Wu, Y; Zagon, IS | 1 |
Freeman, J; Gent, JP; Goodchild, CS; Guo, Z | 1 |
Kamei, J; Nagase, H; Sodeyama, M; Suzuki, T; Tsuda, M | 1 |
Burden, HW; Davis, MC; Hodson, CA | 1 |
Manfredi, B; Mantegazza, P; Panerai, AE; Sacerdote, P | 1 |
Bartosz-Bechowski, H; Davis, P; Hruby, VJ; Kramer, TH; Porreca, F | 1 |
Lishmanov, YB; Maslov, LN; Smagin, GN; Ugdyzhekova, DS | 1 |
Lin, CE; Mello, NK; Negus, SS; Portoghese, PS | 1 |
Coulais, Y; Francés, B; Goeldner, M; Guiraud, R; Hirth, C; Méjean-Galzi, A; Tafani, JA; Zajac, JM | 1 |
Ahtee, L; Katajamäki, J; Kivastik, T; Piepponen, TP; Zharkovsky, A | 1 |
Lishmanov, IB; Maslov, LN; Ugdyzhekova, DS | 1 |
Abbruscato, TJ; Davis, TP; Hruby, VJ; Thomas, SA | 1 |
Chapman, I; Hope, PJ; Horowitz, M; Morley, JE; Wittert, GA | 1 |
Giuliani, S; Maggi, CA | 1 |
Gordon, FJ; Holtzman, SG; Patterson, AB | 1 |
Fekete, MI; Gergely, P; Murányi, A; Nagy, GM | 1 |
Dahl, SG; Diop, L; Friese, N; Lambert, C; Rivière, PJ | 1 |
Andrić, S; Kostić, T; Kovacević, R; Marić, D | 1 |
Alvarez, M; Cabré, L; Carrasco, G; Costa, J; Hernández, E; Molina, R; Puiggrós, A; Seoane, A; Sobrepere, G | 1 |
Civelek, AC; Dannals, RF; Dixon, RB; Joh, T; Kao, PF; Kim, S; Ravert, HT; Villemagne, VL; Wagner, HN | 1 |
Childers, SR; Sim, LJ | 1 |
Lysle, DT; Perez, L | 1 |
Picker, MJ | 1 |
Bicknell, RJ; Dye, S; Leng, G | 1 |
Sullivan, JR; Watson, A | 1 |
Józefowski, S; Płytycz, B | 1 |
Kosten, TR; O'Connor, PG | 1 |
Adams, DJ; Trequattrini, C | 1 |
Aasmundstad, TA; Alkana, RL; Grung, M; Handal, M; Mørland, J; Skurtveit, S | 1 |
Aimi, N; Matsumoto, K; Sakai, S; Takayama, H; Thongpradichote, S; Tohda, M; Watanabe, H | 1 |
Fujimoto, JM; Holmes, BB; Rady, JJ | 1 |
Büchele, W; Burkhardt, D; Bussello-Spieth, B; Reiss, J; Tretter, F; Walcher, S | 1 |
Brewer, C; Gastfriend, DR | 1 |
Gu, Y; Huang, LY; Lai, SL | 1 |
Kizawa, Y; Koike, K; Okayasu, A; Suzuki, T; Takayanagi, I | 1 |
Gray, AM; Sewell, RD; Spencer, PS | 1 |
Borsodi, A; Hosztafi, S; Nevin, ST; Rónai, AZ; Spetea, M; Tóth, G | 1 |
Collins, PD; Cook, TM | 1 |
Matsuzawa, S; Misawa, M; Nagase, H; Suzuki, T | 2 |
Xie, CW; Yu, TP | 1 |
Choleris, E; Colwell, DD; Kavaliers, M | 1 |
Brown, CH; Leng, G; Ludwig, M | 1 |
Borg, L; Gunduz, M; Ho, A; King, A; Kreek, MJ; Maniar, S; Perret, G; Porter, M; Schluger, JH | 1 |
Becker, A; Grecksch, G; Hoellt, V; Schroeder, H; Schroeder, U | 1 |
Carter, C; Cherian, E; Mendes, M; Pryor, SC | 1 |
Kameyama, T; Shinkai, N; Ukai, M | 1 |
Kita, H; Miura, T; Nozawa, Y; Shimamoto, K; Tanno, M; Tsuchida, A | 1 |
Borg, L; Gunduz, M; Ho, A; Kreek, MJ; Schluger, J | 1 |
Akil, H; Clark, MJ; Mansour, A; Medzihradsky, F; Remmers, AE; Woods, JH | 1 |
Fujimoto, JM; Gorny, JM; Rady, JJ | 1 |
Fan, XT; Kitamura, K; Oka, T; Taniguchi, T | 1 |
Gray, AM; Nevinson, MJ; Sewell, RD | 1 |
Liu, H; Mazarati, A; Wasterlain, C | 1 |
Arcaya, JL; Cano, G; Gómez, G; Maixner, W; Suárez-Roca, H | 1 |
Hirtl, C; Pfab, R; Zilker, T | 1 |
Minami, M; Nakagawa, T; Ozawa, T; Satoh, M; Watanabe, T | 1 |
Hallermann, S; Müller, W; Swandulla, D | 1 |
Deacon, M; Sluka, KA; Stibal, A; Strissel, S; Terpstra, A | 1 |
Chumpa, A | 1 |
Grigdesby, CF; March, PA; Suckow, MA; Terril, LA | 1 |
Fujimura, T; Kastin, AJ; Katsuyama, S; Murayama, K; Sakurada, S; Sakurada, T; Ueda, H; Yuki, M; Zadina, JE | 1 |
Gross, GJ; Liang, BT | 1 |
Calabro, JJ; Gaddis, GM; Gin-Shaw, SL; Harchelroad, FP; Kaplan, JL; Marx, JA; Spiller, JD; Spivey, WL; Zhao, N | 1 |
France, CP; Gauthier, CA | 1 |
Minami, M; Nakagawa, T; Ozawa, T; Satoh, M | 1 |
Fischer, A; Undem, BJ | 1 |
Maslov, LN; Naryzhnaya, NV; Tam, SW | 1 |
Benyhe, S; Borsodi, A; Medzihradszky, K; Orosz, G; Rónai, AZ; Sartania, N; Szatmári, I | 1 |
Aston-Jones, G; Delfs, JM; Druhan, J; Zhu, Y | 1 |
Gumułka, SW; Kolaric, S; Makulska-Nowak, HE; Mizerska, K | 1 |
Cheng, CH; Naylor, RJ; Ngan, MP; Rudd, JA; Wai, MK | 1 |
Amico, MC; Mattioli, F; Morrone, LA; Romanelli, L; Valeri, P | 1 |
Baamonde, A; Gutiérrez, M; Hidalgo, A; Menéndez, L; SanMartín, S | 1 |
Hölter, SM; Spanagel, R | 1 |
Chu, XP; Li, P; Wang, JQ; Xu, NS | 1 |
Fujii, T; Goto, T; Motoyama, Y; Ochi, T | 1 |
Froehlich, JC; June, HL; Li, TK; McCane, SR; Portoghese, PS; Zink, RW | 1 |
Cullen, DJ; Dwyer, MJ; Gold, CG; Gonzales, S; Houtmeyers, D | 1 |
Foldes, JK; Hauser, KF; Turbek, CS | 1 |
Lin, BC; Ni, X; Song, CY; Wang, CH | 1 |
Lundeberg, T; Yu, LC; Zhang, YP | 1 |
Cui, RY; Jiang, CL; Liu, XY; Lu, CL; Son, LX; Sun, LY; Wang, YX; You, ZD | 1 |
Bilecki, W; Höllt, V; Przewłocki, R | 1 |
Bocchi, C; Delsignore, R; Fontanesi, B; Gerra, G; Rustichelli, P; Timpano, M; Zaimovic, A; Zambelli, U | 1 |
Kamei, J; Nagase, H; Ohsawa, M; Zushida, K | 1 |
Castells, MT; Laorden, ML; Martínez, MD; Martínez, PJ; Milanés, MV | 1 |
Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, S; Tadano, T; Takahashi, N; Tan-No, K; Yonezawa, A | 1 |
Hayashi, T; Kisara, K; Kutsuwa, M; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeda, S; Tan-No, K; Yuki, M | 1 |
Hiramatsu, M; Inoue, K | 1 |
Baumer, F; Bodnar, RJ; Pasternak, GW; Rossi, GC; Stein, JA; Znamensky, V | 1 |
Berntsson, A; Eirefelt, M; Söderpalm, B; Svensson, AI | 1 |
Gyires, K; Müllner, K; Rónai, AZ | 1 |
Befort, K; Chluba, J; Dierich, A; Filliol, D; Gavériaux-Ruff, C; Ghozland, S; Kieffer, BL; LeMeur, M; Maldonado, R; Martin, M; Matthes, HW; Simonin, F; Valverde, O | 1 |
Arakawa, K; Saito, N; Sasaki, T; Shimada, K | 1 |
Newman, LC; Stevens, CW; Wallace, DR | 1 |
Ballet, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A | 1 |
Cheong, YP; Cho, KP; Kim, CJ; Kim, JK; Kim, KW; Kwun, J; Woo, RS | 1 |
Scholz, M | 1 |
Sadée, W; Surratt, CK; Wang, D | 1 |
Hirohashi, M; Kitano, Y; Komiyama, C; Makino, M; Takasuna, K | 1 |
Mello, NK; Negus, SS | 1 |
Abdel-Fattah, AM; Matsumoto, K; Watanabe, H | 1 |
Gibbons, N; Kapasi, AA; Mattana, J; Singhal, PC | 1 |
Arai, K; Furuta, S; Hayashi, T; Katsuyama, S; Kisara, K; Miyazaki, S; Onodera, K; Sakurada, S; Sato, T; Yonezawa, A | 1 |
Akil, H; Bonner, G; Meng, F | 1 |
Cañadas, F; Rice, KC; Riley, AL; Stevenson, GW; Zhang, X | 1 |
Azzolina, O; Barbieri, A; Collina, S; Ghislandi, V; Lanza, E; Sbacchi, M; Scheideler, MA; Vercesi, D | 1 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE | 1 |
Porter, SJ; Somogyi, AA; White, JM | 2 |
Kuzmin, A; Ogren, SO; Sandin, J; Terenius, L | 1 |
Boto, I; Gomes, PC; Henriques, V; Macedo, TR; Morgadinho, MT; Nunes, SV; Pacheco, F; Pinto, CM; Ramalheira, C; Relvas, J; Ruis, GR; Vale, LL; Ventura, M | 1 |
Chao, CC; Hegg, CC; Hu, S; Peterson, PK; Thayer, S | 1 |
Błaszczyk, JW; Lapo, I; Sadowski, B; Tajchert, K | 1 |
Lutfy, K; Maidment, NT | 1 |
Inagaki, N; Kawasaki, H; Nagai, H; Nagao, M; Nakamura, N | 1 |
Barr, GA; Jones, KL | 1 |
Dello Buono, FA; Friedman, JD | 1 |
Hyytiä, P; Kiianmaa, K | 1 |
Yui, K | 1 |
Oliveira, MA; Prado, WA | 1 |
Cho, KP; Kim, KW; Shin, BS; Son, Y | 1 |
Cavun, S; Evec, AD; Millington, WR; Rapacon-Baker, MM; Resch, GE | 1 |
Endoh, T; Izumimoto, N; Kamei, J; Mizoguchi, H; Nagase, H; Narita, M; Saitoh, A; Suzuki, T; Tajima, A; Tseng, LF | 1 |
Benowitz, NL; Levine, JD; Miao, FJ | 1 |
Boucher, M; Coudoré-Civiale, MA; Eschalier, A; Fournié-Zaluski, MC; Méen, M; Roques, BP | 1 |
Neilan, CL; Nguyen, TM; Pasternak, GW; Schiller, PW | 1 |
Alt, A; Fan, CD; McFadyen, IJ; Traynor, JR; Woods, JH | 1 |
Kalra, A; Sluka, KA; Urban, MO | 1 |
Liu, JG; Prather, PL | 2 |
Bilsky, EJ; Raehal, KM; Sadée, W; Wang, D | 1 |
Binder, W; Junien, JL; Machelska, H; Mousa, S; Rivière, PJ; Schäfer, M; Schmitt, T; Stein, C | 1 |
McPherson, BC; Yao, Z | 1 |
Bhandari, RN; Clarke, RW; Leggett, J | 1 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE | 1 |
Gekker, G; Lokensgard, JR; Peterson, PK | 1 |
Kieffer, BL; Maidment, NT; Matthes, HW; Skoubis, PD; Walwyn, WM | 1 |
David, S; Lancaster, T; Stead, LF | 1 |
Konopińska, D; Plech, A; Rykaczewska-Czerwińska, M | 1 |
Xu, K; Yang, G; Zhou, W | 1 |
Katoh, T; Mamiya, T; Ukai, M | 1 |
Chuang, LF; Chuang, RY; Chuang, TK; Doi, RH; Suzuki, S | 1 |
Amos, HE; Azain, MJ; Barb, CR; Edwards, GL; Froetschel, MA | 1 |
Castellan-Baldan, L; Coimbra, NC; Corrêa, SA; Da Silva, LA; Eichenberger, GC; Maruoka, RY; Osaki, MY; Resende, GC; Ribeiro, SJ | 1 |
Agarwal, SS; Dhar, MM; Haq, W; Narayan, P; Raghubir, R; Singh, VK; Tandon, R | 1 |
Lutz, EA; Shannon, HE | 1 |
Gross, GJ; Krylatov, AV; Lishmanov, IuB; Maslov, LN; Naryzhnaia, NV; Stephano, JB | 1 |
Kuraishi, Y; Miyamoto, T; Nakahashi, T; Nojima, H; Shinkado, T | 1 |
Cancela, LM; del Rosario Capriles, N | 1 |
Li, JJ; Li, Y; Yu, LC | 1 |
Hao, S; Iwasaki, H; Mamiya, K; Takahata, O | 1 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE | 1 |
McCormick, SE; Stoessl, AJ | 1 |
Gabriel, A; Grond, S; Huang, YH; Lu, JT; Meuser, T; Pierce Palmer, P; Pietruck, C; Yu, LC | 1 |
Imai, S; Itou, Y; Narita, M; Suzuki, T; Yajima, Y | 1 |
Bardo, MT; Gehrke, BJ; Phillips, SB; Rauhut, AS | 1 |
Bastia, E; Bertorelli, R; Citterio, F; Corradini, L; Forlani, A; Ongini, E | 1 |
Dimitrijević, M; Kovacević-Jovanović, V; Radulović, J; Stanojević, S; Vujić, V | 1 |
Ciccocioppo, R; Martin-Fardon, R; Weiss, F | 1 |
González-Maeso, J; Meana, JJ; Rodríguez-Puertas, R | 1 |
Schmidt, H; Trosko, O; Zemtsovski, MJ | 1 |
Ho, IK; Rockhold, RW; Sinchaisuk, S | 1 |
Arvidsson, U; Kela, J; Salmi, P; Wahlestedt, C | 1 |
Bardo, MT; Gehrke, BJ; Rauhut, AS; Shortridge, BE | 1 |
Hu, DY; Kai, L; Liu, LM; Shi, YL; Wang, ZF | 1 |
Qian, X; Soong, Y; Szeto, HH; Wu, D; Zhao, GM | 1 |
Holtzman, SG; White, DA | 1 |
Bujdosó, E; Farkas, J; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
Kamei, J; Morita, K; Nagase, H; Saitoh, A | 1 |
Baraban, JM; Reti, IM | 1 |
Ballachey, BE; McCormick, C; Monson, DH | 1 |
Chen, CJ; Chen, WY; Liao, SL; Raung, SL | 1 |
Cheung, YF; Li, GR; Wong, TM; Xiao, GS; Zhou, JJ | 1 |
Li, J; Li, QX; Qi, JJ; Ye, CY; Yu, XL; Zhang, DC | 1 |
Lundeberg, T; Yu, LC; Yu, SQ | 1 |
Raffa, RB; Stagliano, GW; Umeda, S | 1 |
Brillet, K; Bucher, B; Lecat, S; Pattus, F; Perret, BG; Rabut, G; Wagner, R | 1 |
Barrington, PL; Ellenberger, EA; Lucas, HL; Mueller, JL; Quock, RM; Russo, JM; Tseng, LF | 1 |
Brailoiu, GC; Dun, NJ; Ohtubo, Y; Wu, SY | 1 |
Darpolar, M; Kampine, JP; Leitermann, RJ; Sun, HS; Tseng, LF; Wu, HE | 1 |
Bédard, PJ; Grégoire, L; Samadi, P | 1 |
Law, PY; Loh, HH; Portoghese, PS | 1 |
Bennett, L; Ratka, A | 1 |
Tzschentke, TM | 1 |
Calvo, F; Carvalho, AD; Castellan-Baldan, L; Coimbra, NC; da Silva, LA; de Oliveira, R; Elias-Filho, DH; Felippotti, TT; Motta, V; Osaki, MY; Paschoalin-Maurin, T; Ubiali, WA | 1 |
Bogdanov, AI; Yarushkina, NI | 1 |
Gallate, JE; Mallet, PE; McGregor, IS | 1 |
Adair, ER; Cobb, BL; Jauchem, JR | 1 |
Bieber, A; Chung, E; Day, E; Ohgami, Y; Quock, RM | 1 |
Laurito, CE; Lu, Y; Sweitzer, SM; Yeomans, DC | 1 |
Hallmark, RA; Hunt, PS | 1 |
Fujimoto, JM; Leitermann, RJ; Sun, HS; Thompson, J; Tseng, LF; Wu, HE | 1 |
Albuquerque, EX; Almeida, LE; Camara, AL; Maelicke, A; Pereira, EF | 1 |
Cohen, E; Goodchild, CS; Nadeson, R | 1 |
Kotz, CM; Levine, AS; Sweet, DC | 1 |
Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Suzuki, T; Takada, K | 1 |
Chen, CM; Huang, EY; Tao, PL | 1 |
Gao, L; Yu, LC | 1 |
Cox, ML; Welch, SP | 1 |
Bespalov, A; Danysz, W; Kashkin, V; Malyshkin, A; Neznanova, O; Sukhotina, I; Zakharova, E | 1 |
Christophersen, AS; Frogopsahl, G; Mørland, J; Olsen, L; Waal, H | 1 |
Blum, HE; Kreisel, W; Opitz, OG; Thimme, R | 1 |
Fujimura, T; Ito, K; Kawamura, S; Mizoguchi, H; Murayama, K; Nakayama, D; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H | 1 |
Claude-Geppert, PA; Erickson-Herbrandson, LJ; Law, PY; Liu, J; Loh, HH; Solberg, J | 1 |
Gammie, SC; Garland, T; Girard, I; Li, G; Rhodes, JS | 1 |
Fürst, Z; Gyarmati, Z; Timár, J | 1 |
Lai, H | 1 |
Bilsky, EJ; Sadée, W; Wang, D | 1 |
Ambo, A; Bryant, SD; Fujita, Y; Jinsmaa, Y; Lazarus, LH; Li, T; Miyazaki, A; Okada, Y; Sasaki, Y; Shiotani, K; Tsuda, Y | 1 |
Bhamidipati, CM; Bilsky, EJ; Blair, JR; Lowery, JJ; Paolino, RM; Raehal, KM; Sadée, W; Wang, D | 1 |
Coimbra, NC; Freitas, RL; Kishi, R; Morato, S; Rebouças, EC; Savoldi, M; Segato, EN | 1 |
Amico, MC; Morrone, LA; Palmery, M; Romanelli, L; Tucci, P; Valeri, P | 1 |
Sterious, SN; Walker, EA | 1 |
Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Oi, Y; Suzuki, T; Takada, K | 1 |
Guen, SL; Kieffer, BL; Nieto, MM; Noble, F; Roques, BP | 1 |
Chang, WL; Lee, SS; Su, MJ | 1 |
Daniel, AM; Papini, MR; Pellegrini, S; Wood, M | 1 |
Cassel, JC | 1 |
R Jauchem, J | 1 |
Aimi, N; Horie, S; Ishikawa, H; Matsumoto, K; Murayama, T; Ponglux, D; Takayama, H; Watanabe, K | 1 |
Aragon, CM; Pastor, R | 1 |
Benabid, AL; Berger, F; Buggia, V; Gilbert, F; Lévesque, D; Sgambato-Faure, V | 1 |
Fantegrossi, WE; Koreeda, M; Kugle, KM; Valdes, LJ; Woods, JH | 1 |
Gackenheimer, SL; Gehlert, DR; Mitch, CH; Pintar, JE; Quimby, SJ; Statnick, MA; Suter, TM; Wheeler, WJ | 1 |
Farrell, PA; Loomis, JL; Rodd, DW | 1 |
Koseki, M; Matsumura, E; Sakaguchi, M; Wakamatsu, M | 1 |
Fan, GX; Tang, JS; Wang, JY; Yuan, YK; Zeng, XY | 1 |
Acquas, E; Di Chiara, G; Fenu, S; Pisanu, A | 1 |
Ali, R; Gowing, L; White, J | 1 |
Arita, H; Chiba, S; Hanaoka, K; Hayashida, M; Sekiyama, H; Shu, H | 1 |
Flau, K; Kathmann, M; Redmer, A; Schlicker, E; Tränkle, C | 1 |
Xiong, W; Yu, LC | 1 |
Guido, M; Lanzone, A; Romualdi, D | 1 |
Aydin, S; Beis, R; Herekman-Demir, T; Oztürk, Y | 1 |
Chugh, C; Jain, H; Mediratta, PK; Rathi, N; Reeta, Kh; Sharma, KK | 1 |
Ambo, A; Bryant, SD; Fujita, Y; Jinsmaa, Y; Lazarus, LH; Li, T; Marczak, E; Miyazaki, A; Okada, Y; Sasaki, Y; Shiotani, K; Tsuda, Y | 1 |
Gottheil, E; Mannelli, P; Van Bockstaele, EJ | 1 |
Augar, R; Berryman, N; Hansom, CJ; O'Mahony, ML; Palmer, RM; Rodgers, RJ; Stevens, A; Tallett, AJ | 1 |
Bagosi, Z; Bujdosó, E; Jászberényi, M; Szabó, G; Telegdy, G | 1 |
Agirregoitia, E; Carracedo, A; Casis, L; Gil, J; Irazusta, J; Ochoa, C; Subiran, N; Valdivia, A | 1 |
David, S; Evins, AE; Lancaster, T; Stead, LF | 1 |
Gu, XL; Yu, LC | 1 |
Adrian, R; Koob, GF; Solbrig, MV; Wechsler, SL | 1 |
Barzakh, EI; Lasukova, TV; Lishmanov, YB; Maslov, LN; Oeltgen, PR; Rice, KK | 1 |
Fushiki, T; Inoue, K; Matsumura, S; Mizushige, T; Tsuzuki, S; Yoneda, T | 1 |
Kamei, J; Nozaki, C | 1 |
Bigliardi, PL; Bigliardi-Qi, M; Büchner, S; Jost, G; Rufli, T; Stammer, H | 1 |
Baeva, TA; Gein, SV; Kichanova, OA | 1 |
Chen, TY; Gomery, P; Israel, R; Rosow, CE; Stambler, N; Stefanovich, P | 1 |
Garcia, JG; Moreno-Vinasco, L; Moss, J; Sammani, S; Singleton, PA; Wanderling, SL | 1 |
Lasukova, TV; Lishmanov, AIu; Maslov, LN; Platonov, AA | 1 |
Dinnebier, RE; Sugimoto, K; Zakrzewski, M | 1 |
Andoh, T; Kuraishi, Y; Nakashima, Y; Sasaki, A; Shiraki, K; Takasaki, I | 1 |
Gu, XL; Sun, YG; Yu, LC | 1 |
Alloui, A; Baron, A; Blondeau, N; Cupo, A; Diochot, S; Eschalier, A; Escoubas, P; Gélot, A; Heurteaux, C; Lazdunski, M; Mazzuca, M; Voilley, N; Zimmer, A; Zimmer, AM | 1 |
Honda, T; Katsura, M; Ohkuma, S; Shibasaki, M; Sumimoto, A; Torigoe, F; Tsujimura, A | 1 |
Burger, MC; Cramb, DT; Dahms, TE; Massotte, D; Swift, JL | 1 |
Howells, RD; Wannemacher, KM; Yadav, PN | 1 |
Ahn, DK; Han, SR; Jeon, HJ; Ju, JS; Kim, SK; Lee, MK; Lim, KH; Yang, GY; Yoon, YW | 1 |
Benturquia, N; Bilkei-Gorzo, A; Noble, F; Roques, BP; Zimmer, A | 1 |
Chen, Z; Li, T; Zhang, B | 1 |
Chen, Q; Dong, L; Fu, CY; Ni, JM; Wang, R; Zhao, YL | 1 |
Arout, CA; Inturrisi, CE; Juni, A; Kest, B; Klein, G; Waxman, AR | 1 |
Boyce, D; Carr, DB; McNicol, ED; Schumann, R | 1 |
Fogel, WA; Stasiak, A | 1 |
Huang, FS; Tang, JS; Wang, JY; Yuan, YK; Zhao, M | 1 |
Komatsu, T; Mizoguchi, H; Morimoto, M; Sakurada, S; Sakurada, T; Sato, T; Sawai, T; Watanabe, C; Watanabe, H; Yonezawa, A | 1 |
Brown, K; Coats, BD; Crysdale, NY; Harrison, JA; Hutchinson, MR; Maier, SF; Patel, SJ; Rice, KC; Sholar, PW; Shridhar, M; Watkins, LR; Zhang, Y | 1 |
Abrahao, KP; Quadros, IM; Souza-Formigoni, ML | 1 |
Meerpohl, JJ; Timmer, A | 1 |
Bagosi, Z; Jászberényi, M; Telegdy, G | 1 |
Beck, P; Bonacorso, HG; Drewes, C; Ferreira, J; Machado, P; Martins, MA; Mello, CF; Milano, J; Oliveira, SM; Rossato, MF; Rubin, MA; Zanatta, N | 1 |
Gyires, K; Zádori, Z | 1 |
Emel'yanova, TG; Guzevatikh, LS; Kolotilova, AB; Valujskikh, DV | 1 |
Brocardo, PS; Budni, J; Lobato, KR; Rodrigues, AL; Santos, AR | 1 |
Bradbury, FA; Carroll, FI; Divin, MF; Traynor, JR | 1 |
Achat-Mendes, C; Platt, DM; Rowlett, JK; Spealman, RD; Valdez, GR | 1 |
Matulonis, JE; Pan, YX; Pasternak, GW; Rossi, GC; Xu, J; Xu, M | 1 |
Holzer, P | 2 |
Arout, CA; Dahan, A; Kest, B; Kowalczyk, WJ; Morariu, AM; Sarton, EY; van Dorp, EL; Waxman, AR | 1 |
Morato, GS; Varaschin, RK | 1 |
Daniel, AM; Ortega, LA; Papini, MR | 1 |
Bing, G; Jang, CG; Kim, HC; Koo, KH; Nabeshima, T; Oh, CH; Oh, KW; Park, DH; Shin, EJ; Yamada, K | 1 |
Frishtick, R; Pick, CG; Rubovitch, V; Schreiber, S; Volis, I; Weizman, R | 1 |
Daali, Y; Dayer, P; Desmeules, J; Kanaan, M | 1 |
Nizhnikov, ME; Pautassi, RM; Spear, NE; Truxell, E | 1 |
Chen, YF; Chiang, HM; Tsai, HY; Tsai, YT | 1 |
Ali, R; Gowing, L; White, JM | 3 |
Bartolini, A; Bergonzi, MC; Bilia, AR; Galeotti, N; Ghelardini, C; Vivoli, E | 1 |
Cooper, PD; Cowlings, A; Dennis, SR; Donnelly, C; Woodman, JD | 1 |
Jin, WY; Liu, D; Liu, Z; Yu, LC | 1 |
Boyce, R; Leung, LS; Ma, J | 1 |
Bramness, J; Gossop, M; Lobmaier, P; Waal, H | 1 |
Kapoor, S | 1 |
Baker, JE; Falck, JR; Gross, GJ; Hsu, A; Nithipatikom, K; Wu, HE | 1 |
Ismayilova, N; Shoaib, M | 1 |
Howland, RH | 1 |
Bernhard, JD; Luger, TA; Phan, NQ; Ständer, S | 1 |
Beinborn, M; Ci, L; Fortin, JP; Goldstein, C; Huggins, GS; Kopin, AS; Montefusco, MC; Peter, I; Reis, SE; Schroeder, J | 1 |
Baiula, M; Bedini, A; De Marco, R; Gentilucci, L; Spampinato, S; Tolomelli, A | 1 |
Leppert, W | 1 |
Bonds, JA; Dalton, ND; Head, BP; Horikawa, YT; Panneerselvam, M; Patel, HH; Patel, PM; Roth, DM; Saldana, M; Tsutsumi, YM | 1 |
Blumell, BR; Hansen, DM; Park, JJ; Steffensen, SC; Wilcox, JD; Yang, CH; Yoon, SS | 1 |
Malek, S; Mottaghi, K; Safari, F; Salimi, A | 1 |
Salari, AA; Solati, J; Zarrindast, MR | 1 |
Chen, Q; Ge, WW; Lu, SS; Tian, XZ; Yang, AM; Yang, QZ | 1 |
Janssen, P; Pottel, H; Tack, J; Vos, R | 1 |
den Hollander, BR; Pattij, T; Schetters, D; Schoffelmeer, AN; van Es, IE; van Mourik, Y; Wiskerke, J | 1 |
Kim, JH; Kim, JI; Kim, TW; Kim, WY; Lee, YS; Min, TJ; Noh, KH; Park, YC | 1 |
Cabañero, D; Campillo, A; García-Nogales, P; Puig, MM; Romero, A | 1 |
Evans, CJ; Hales, TG; Lam, H; Maga, M; Maidment, NT; Pradhan, A; Walwyn, W | 1 |
De Castro E Silva, E; Ferreira, HS; Fregoneze, JB; Oliveira, EF; Ribeiro, VF | 1 |
Bagosi, Z; Csabafi, K; Jászberényi, M; Telegdy, G; Tóth, G; Wollemann, M | 1 |
Hagemann, TM; Miller, JL | 1 |
Acquas, E; Fois, GR; Muggironi, G; Peana, AT; Vinci, S; Zinellu, M | 1 |
Chen, Q; Ge, WW; Lu, SS; Mi, ZY; Su, SF; Yang, AM; Yang, SB | 1 |
Assreuy, AM; Benevides, RG; Cavada, BS; Celedônio, NR; Coelho-de-Souza, AN; de Freitas Pires, A; Leal-Cardoso, JH; Lopes, ÉA; Nagano, CS; Rodrigues, NV; Santos, CF; Soares, CE; Sousa, PL | 1 |
Goyal, R; Kumar, K; Mohan, A; Mudgal, A; Pasha, S | 1 |
Kuwabara, H; McCaul, ME; Wand, GS; Weerts, EM; Wong, DF; Xu, X | 1 |
Costantino, CM; Devi, LA; Gomes, I; Lim, MP; Stockton, SD | 1 |
Nassim, BE; Wang, ML | 1 |
Andoh, T; Kuraishi, Y; Lee, JB; Yoshida, T | 1 |
Aragona, BJ; Krzywosinski, T; Kuhnmuench, M; Resendez, SL | 1 |
Chen, Q; Lv, SY; Qin, YJ; Wang, HT; Xu, N; Yang, YJ | 1 |
Chen, Q; Lv, SY; Qin, YJ; Wang, NB; Yang, YJ | 1 |
Koob, GF; Misra, KK; Schlosburg, JE; Vendruscolo, LF; Wee, S | 1 |
Dong, S; Li, M; Ma, G; Zhou, L | 1 |
Law, F; Melichar, J; O'Shea, J; Praveen, KT | 1 |
Johanek, LM; King, EW; Sato, KL; Sluka, KA | 1 |
Arulselvan, P; Fakurazi, S; Hairuszah, I; Hidayat, MT; Moklas, MAM; Shamima, AR | 1 |
Bagetta, G; Katsuyama, S; Komatsu, T; Kuwahata, H; Mizoguchi, H; Nagaoka, K; Nakamura, H; Sakurada, S; Sakurada, T | 1 |
Hasson, A; Hillhouse, M; Lindblad, R; Ling, W; McCormack, J; Mooney, LJ; Nielsen, S; Saxon, A; Stablein, D; Thomas, C | 1 |
Cao, S; Dong, S; Li, M; Ma, G; Zhou, L | 1 |
Boeira, SP; de Gomes, MG; Del Fabbro, L; Filho, CB; Goes, AT; Jesse, CR; Souza, LC | 1 |
Bailey, A; Garg, N; Kumar, N | 1 |
Geĭn, SV; Sharav'eva, IL | 1 |
Ingram, SL; Lamberts, JT; Li, MH; Neubig, RR; Smith, CE; Traynor, JR | 1 |
Ise, Y; Katayama, S; Mori, T; Nagase, H; Suzuki, T | 1 |
Discala, JF; Gruber, RB; Lewis, SJ; May, WJ; McLaughlin, D; Palmer, LA; Young, AP | 1 |
Pergolizzi, JV; Porreca, F; Raffa, RB; Taylor, R | 1 |
Bach-Rojecky, L; Drinovac, V; Lacković, Z; Matak, I | 1 |
Hisa, H; Mutoh, J; Ohsawa, M | 1 |
Hahn, JH; Nguyen, TA; Strakowski, SM | 1 |
Hackel, D; Peng, F; Rittner, HL; Wang, Y | 1 |
Bezawada, P; Coop, A; Healy, JR; Jones, JW; Kane, MA; MacKerell, AD; Matsumoto, RR; Shim, J | 1 |
David, SP; Evins, AE; Lancaster, T; Prochaska, JJ; Stead, LF | 1 |
Brenner, DM; Ford, AC; Schoenfeld, PS | 1 |
McCarberg, BH | 1 |
Athayde, ML; Boligon, AA; Bonacorso, HG; Calixto, JB; Ferreira, J; Machado, P; Martins, MA; Oliveira, SM; Rosa, F; Rossato, MF; Rubin, MA; Silva, CR; Tonello, R; Trevisan, G; Walker, CI; Zanatta, N | 1 |
Ganno, ML; McLaughlin, JP; Patkar, KA; Rasakham, K; Ross, NC; Singh, HD; Toll, L; Wu, J | 1 |
Kiguchi, N; Kishioka, S; Ko, MC; Kobayashi, Y; Saika, F; Wakida, N; Woods, JH; Yamamoto, C | 1 |
Dobek, E; Górski, K; Misztal, T; Romanowicz, K | 1 |
Cervantes-Durán, C; Espinosa de los Monteros-Zuñiga, A; Godínez-Chaparro, B; Izquierdo, T; Lozada, MC | 1 |
Prado, WA; Silva, JR; Silva, ML | 1 |
Bilsky, EJ; Cain, JP; Hruby, VJ; Hu, J; Kumirov, VK; Lee, YS; Podolsky, AT; Sandweiss, A; Vanderah, TW; Vardanyan, RS | 1 |
Kon-No, T; Mizoguchi, H; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H; Yonezawa, A | 1 |
Badger, GJ; Brooklyn, JR; Dunn, KE; Heil, SH; Higgins, ST; Patrick, ME; Saulsgiver, K; Sigmon, SC | 1 |
Hamzah, AS; Kek, TL; Mansor, NS; Mohammat, MF; Salleh, MZ; Sani, MH; Shaameri, Z; Zakaria, ZA | 1 |
Anisimova, VA; Grechko, OIu; Shtareva, DM; Spasov, AA | 1 |
Barnett, V; Mihalyo, M; Twycross, R; Wilcock, A | 1 |
Duarte, ID; Pacheco, Dda F; Romero, TR | 1 |
Williams, JT | 1 |
Amato, L; Bellisario, C; Davoli, M; Minozzi, S | 1 |
Correa, FM; Fassini, A; Resstel, LB; Scopinho, AA | 1 |
Bregonzio, C; de Di Nasso, EG; Gamboa, DF; Pennacchio, GE; Soaje, M; Valdez, SR | 1 |
Bullmore, ET; Felici, A; Henderson, G; Kelly, E; Maltby, K; Mundell, SJ; Nathan, PJ; Roth, AL; Sava, A | 1 |
Ise, Y; Itoh, T; Komiya, S; Masukawa, D; Mizuo, K; Mori, T; Saeki, T; Shibasaki, M; Suzuki, T; Yoshizawa, K | 1 |
Bawor, M; Bonner, A; Daiter, J; Dennis, BB; Desai, D; Marsh, DC; Naji, L; Pare, G; Plater, C; Samaan, Z; Thabane, L; Varenbut, M; Worster, A | 1 |
Herrero, JF; Herrero-Zorita, C; Ramos-Zepeda, GA | 1 |
Adachi, S; Fushiki, T; Inoue, K; Matsumura, S; Okafuji, Y; Okahashi, T; Sakamoto, K; Tsuzuki, S | 1 |
Aranda-Fernández, PE; Chotro, MG; Gaztañaga, M | 1 |
Baeva, TA; Gein, SV; Nebogatikov, VO | 1 |
Hotta, H; Piché, M; Watanabe, N | 1 |
Farré-Albaladejo, M; Fernández-Nieva, Z; Gascón-Crespí, I; Hernández, RM; Igartua, M; Moreno-Vicente, R; Navarro, A; Pedraz, JL | 1 |
Goumon, Y; Khabbazi, S; Parat, MO | 1 |
Willyard, C | 1 |
Hosztafi, S; Mazák, K; Noszál, B | 1 |
de Groat, WC; Ferroni, MC; Kadow, BT; Kang, A; Lyon, TD; Roppolo, JR; Shen, B; Slater, RC; Tai, C; Wang, J; Xiao, Z; Zhang, Z | 1 |
Ahmedzai, SH; Boland, JW | 1 |
Higashi, Y; Nakamura, K; Saito, M; Shimizu, S; Shimizu, T; Taniuchi, K; Ueba, T; Yawata, T | 1 |
Badke, A; Rosielle, DA | 1 |
Hutchinson, MR; Peng, Y; Rice, KC; Wang, X; Watkins, LR; Yin, H; Zhang, Y | 1 |
Diana, M; Fois, GR | 1 |
Akatsu, R; Horie, S; Kato, S; Matsumoto, K; Mori, T; Saito, S; Shibasaki, M; Suzuki, T; Tashima, K; Umemoto, H | 1 |
Fanton, LE; Fischer, L; Macedo, CG; Tambeli, CH | 1 |
Coggiano, M; Hiranita, T; Katz, JL; Mereu, M; Quarterman, JC; Tanda, G | 1 |
Barnett, G; Bruner, A; Fishman, M; Sharma, B | 1 |
Can, ÖD; Kasap, M | 1 |
Pauwels, A; Rommel, N; Scarpellini, E; Tack, J; Vos, R | 1 |
Cami-Kobeci, G; Fichna, J; Husbands, S; Jarmuż, A; Wasilewski, A; Zielińska, M | 1 |
Allen, AR; Balleine, B; Carter, A; Clark, L; Dowling, NA; Gainsbury, SM; Goudriaan, AE; Grant, J; Hall, W; Hayes, A; Hodgins, D; Lattimore, R; Livingstone, C; Lorenzetti, V; Lubman, D; Murawski, C; Parkes, L; Petry, N; Room, R; Singh, B; Thomas, A; Townshend, P; van Holst, R; Youssef, G; Yücel, M | 1 |
Najafipour, H; Rostamzadeh, F; Yeganeh-Hajahmadi, M | 1 |
Gil, A; Guerri, C; Montesinos, J | 1 |
Kamei, C; Nakasone, T; Sugimoto, Y; Wakuda, H | 1 |
da Luz, SC; Nogueira, CW; Pesarico, AP; Rosa, SG; Tagliapietra, CF | 1 |
Joukar, S; Najafipour, H; Rostamzadeh, F; Yeganeh-Hajahmadi, M | 1 |
Abdossalami Asl, Y; Karami, M; Rezazadeh, M; Yamini, Y | 1 |
Becker, K; Diamant, AL; Ewing, B; Heinzerling, K; Hunter, SB; Lamp, K; Lind, M; Ober, AJ; Osilla, KC; Setodji, CM; Watkins, KE | 1 |
Bobrovskaya, L; Senthilkumaran, M | 1 |
Brenner, DM; Burr, NE; Ford, AC; Luthra, P | 1 |
Candy, B; Jones, L; Larkin, PJ; Stone, P; Vickerstaff, V | 2 |
Baamonde, A; Cernuda-Cernuda, R; Fernández-García, MT; Folgueras, AR; García-Domínguez, M; Hidalgo, A; Lastra, A; Menéndez, L | 1 |
Cutler, SJ; Hemby, SE; Leon, F; McCurdy, CR; McIntosh, S | 1 |
Arnelle, D; Bidlack, JM; Deaver, DR; Fern Toh, M; Knapp, BI; Namchuk, MN; Pin, SS; Plotnikava, M; Wonsey, AM | 1 |
Grahan, B | 1 |
Castañeda-Hernández, G; Chávez-Piña, AE; Landa-Juárez, AY; Ortiz, MI; Pérez-Severiano, F | 1 |
Katsuyama, S; Komatsu, T; Kubota, A; Morinaga, O; Ogawa, K; Okamura, T; Sakurada, C; Sakurada, T; Tabata, K; Takano, F; Tsuzuki, M | 1 |
Katz, JL; Tanda, G; Yue, K; Zanettini, C | 1 |
Heller, NM; Maher, DP; Walia, D | 1 |
Barnes, M; Montana, S; Patel, P; Sharma, P; Singh, R; Thakker, M | 1 |
Almada, RC; Calvo, F; Coimbra, NC; da Silva Soares, R; da Silva, JA; de Paiva, YB; Medeiros, P; Roncon, CM | 1 |
McCranor, BJ; Pierce, SA; Racine, MC; Sciuto, AM; Tressler, J; Tuet, WY; Wong, B | 1 |
Cannaert, A; Deventer, M; Fogarty, M; Mohr, ALA; Stove, CP | 1 |
Caliari, MV; de Almeida, DL; Duarte, IDG; Lima Romero, TR; Paiva-Lima, P; Petrocchi, JA; Queiroz-Junior, C | 1 |
Capim, SL; Côrtes, WDS; Gonçalves, GM; Laureano-Melo, R; Marinho, BG; Oliveira, PA; Vasconcellos, MLAA | 1 |
Bassani da Silva, B; Fernandes Magalhães, S; Gonçalves Dos Santos, G; Parada, CA; Tambeli, CH; Vendramini, PH; Vieira, WF | 1 |
Maslov, LN; Naryzhnaya, NV; Nesterov, EA; Prokudina, ES; Tsibulnikov, SY | 1 |
Annibale, P; Bock, A; Grushevskyi, EO; Heilemann, M; Isbilir, A; Karathanasis, C; Lohse, MJ; Möller, J; Osberg, B; Schütte, C; Sungkaworn, T; Sunkara, V | 1 |
Acevedo-Mackey, D; Acharjee, N; Akhtar, K; Al-Buriahi, MS; Amandi, A; An, Y; Anjum, NA; Asgari, Q; Badiei, B; Baez Vasquez, AY; Bagley, GD; Bahreini, MS; Bajelan, S; Baluja, MQ; Barbieri, MA; Batalha, MA; Bettiol, H; Bhattarai, U; Biset, JC; Bjerg, M; Björnsson, BT; Boag, AM; Borthwick, MS; Boukhris, I; Bragança, MLBM; Breves, JP; Britz-McKibbin, P; Broaddus, RR; Burnell, JE; Camargo, CA; Campo, M; Carlsen, KL; Catchpole, B; Cavalli, L; Chai, C; Chanakya, HN; Chang, AYH; Chantada, A; Chen, W; Chen, X; Chen, Y; Cheng, ZL; Chenoweth, DA; Chhetri, S; Coelho, CCNDS; Coker, ES; Cole, MA; Coniglio, A; Connor, TR; Corbishley, A; D'Arienzo, M; da Silva, AAM; Dai, Y; de Oliveira, BR; Dignac, MF; Dong, A; Dottino, JA; Duo, J; Einarsdottir, IE; Ekanayake, EMDNK; El Fels, L; El Hayany, B; El Shahawy, O; Elliott, RJR; Fabrizi, E; Farkas, K; Fellman, B; Fenoglio, D; Ferrario, M; Flögel, F; Fujiogi, M; Gamage, BD; Ganson, KT; Gao, X; Gärtner, S; Gautam, A; Gautam, S; Gaze, WH; Gosse, JA; Graham, DW; Graham, PA; Guastella, G; Guerrero, S; Gul, M; Guo, B; Guo, X; Gupta, VK; Hafidi, M; Halland, A; Han, W; Hardisty, M; Hasegawa, K; Hess, ST; Heydari, R; Hillary, LS; Holm, R; Huang, L; Jaleh, B; Jayasundara, JASB; Ji, X; Jiang, L; Jones, DL; Kac, G; Kebaili, I; Kelley, JB; Kelum, SHP; Kennedy, LJ; Khan, NA; Khazalpour, S; Khuntia, HK; Kinney, MS; Kommedal, Ø; Koomhin, P; Krawczyk, N; Kæstel, T; Lakmal, MAC; Li, H; Li, K; Li, R; Li, S; Li, W; Li, X; Li, Y; Liang, L; Lin, Y; Lippo, E; Liu, B; Liu, F; Liu, J; Liu, X; Liu, Y; Lodha, D; Loose, DS; López-Meza, P; Lu, F; Lu, KH; Lu, Y; Luo, Y; Ma, B; Malham, SK; Masood, A; Matan, N; McCormick, SD; McDonald, JE; McKenzie, LJ; Melendez, BD; Mikaeili, F; Mir, IR; Mirjalili, MH; Moreno, KP; Moura, IB; Müller, S; Nagata, JM; Nasri, A; Nasrollahzadeh, M; Navarro-Jiménez, E; Nie, E; Nielsen, CU; Nielsen, S; Nøhr, MK; Obeng, B; Odetayo, AA; Ortiz-Barrios, M; Ozgen, C; Pan, X; Parisi, ML; Paskavitz, AL; Patel, AK; Pedersen, M; Pontarollo, N; Potts, CM; Price, C; Pu, Y; Quénéa, K; Rahimi Khonakdari, M; Rather, BA; Raut, P; Regish, AM; Reible, DD; Rezadoost, H; Rizzati, M; Roviello, GN; Roviello, V; Rumpel, C; Sang, J; Sangroula, S; Saraiva, MDCP; Sarker, A; Sayyed, MI; Segoshi, A; Sehar, Z; Shao, X; Shaw, D; Shaw, L; Shekhawat, NS; Shim, JK; Shokouhimehr, M; Short, A; Soliman, PT; Songsamoe, S; Springer-Miller, RH; Stenstad, T; Strobl, E; Sun, R; Syme, H; Thai, L; Tian, G; Tofighi, B; Tonguc, B; Tuyiringire, D; Ulaganathan, N; Ulvestad, E; Varacca, A; Vergalli, S; Verma, DK; Villmones, HC; Wang, D; Wang, H; Wang, J; Wang, L; Wang, M; Wang, S; Wang, Y; Wang, Z; Weedon-Fekjær, H; Weller, SR; West, BE; Wilcox, MH; Wu, W; Wufuer, R; Xia, S; Xiang, H; Xu, H; Yan, L; Yang, RK; Yang, Y; Yates, MS; Ye, Q; Yin, H; Yin, Y; Yuan, Y; Yucesan, M; Yue, W; Zeng, W; Zhang, C; Zhang, D; Zhang, H; Zhang, L; Zhang, Q; Zhang, Y; Zhou, B; Zhou, Y; Zhu, Y; Zhu, Z | 1 |
Spitzberg, AJ; Urner, EM; Wirshing, WC | 1 |
Baamonde, A; González-Rodríguez, S; Lastra, A; Machelska, H; Menéndez, L; Seitz, V; Stein, C | 1 |
Baron, CA; Blinova, K; Johannesen, L; Patel, D; Randolph, AL; Ren, M; Sheng, J; Strauss, DG; Thiebaud, N; Tran, PN; Volpe, DA; Wu, M; Wu, WW | 1 |
Farnaghi, F; Gholami, N; Hassanian-Moghaddam, H; McDonald, R; Saberi, M; Zamani, N | 1 |
Jin, Z; Kim, K; Zhan, CG; Zhang, CH; Zheng, F | 1 |
Board, A; Guy, GP; Jones, CM | 1 |
Kim, SA; Kim, YJ; Lee, GJ; Oh, SB | 1 |
Cruz, JS; de Macedo, FHP; Duarte, IDG; Ferreira, RCM; Gonçalves, WA; Gualdron, M; Machado, FS; Mahecha, GAB; Perez, AC; Rezende, BM; Romero, TRL | 1 |
García, MC | 1 |
Amstislavskaya, TG; de Abreu, MS; Demin, KA; Galstyan, DS; Giacomini, ACVV; Kalueff, AV; Kolesnikova, TO; Petersen, EV; Strekalova, T; Zabegalov, KN | 1 |
Ballet, S; Bermudez, M; De Neve, J; Dumitrascuta, M; Spetea, M; Trovato, O; Wolber, G | 1 |
Hill, LG; Loera, LJ; Zagorski, CM | 1 |
Narayan, RJ; Papich, MG | 1 |
Asher, A; Board, A; Cremer, LJ; Guy, GP; Parker, EM; Schieber, L | 1 |
Daunert, S; Deo, S; Dikici, E; Peyravian, N; Sun, E; Toborek, M | 1 |
Chang, HF; Chang, YC; Chao, YS; Chen, CT; Ke, YY; Law, PY; Lin, SY; Loh, HH; Ou, LC; Shih, C; Tao, PL; Tien, YW; Ueng, SH; Xi, JH; Yeh, SH | 1 |
Eikemo, M; Frost, JJ; Haaker, J; Leknes, S; Trøstheim, M | 1 |
McKew, JC; Sadee, W | 1 |
DeGrado, JR; Dube, KM; Goodberlet, MZ; Habeeb, EA; Lupi, KE; Tran, LK | 1 |
Benéitez García, MC; Colmena Crespo, I; Díez-Orejas, RM; Gil-Alegre, ME; Girón Moreno, R; Goicoechea García, C; Martín Fontelles, MI; Sánchez-Robles, EM | 1 |
Barnett, ML; Chyn, D; Hardy, B; Huskamp, HA; Lewinson, T; Meara, E; Mehrotra, A; Morden, NE; Onsando, M | 1 |
Benito, A; Escamilla, I; Haro, G; Juan, N; Peñalva, C; Renau, J; Sánchez-Llorens, M | 1 |
81 review(s) available for naltrexone and naloxone
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
NIDA's naltrexone research program.
Topics: Clinical Trials as Topic; Conditioning, Psychological; Cyclazocine; Drug Evaluation; Euphoria; Heroin; Heroin Dependence; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Research; Research Support as Topic; United States; United States Substance Abuse and Mental Health Services Administration | 1976 |
Recent progress in research on narcotic antagonists.
Topics: Animals; Benzomorphans; Chemical Phenomena; Chemistry; Cyclazocine; Humans; In Vitro Techniques; Models, Biological; Morphinans; Morphine Derivatives; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Receptors, Opioid; Structure-Activity Relationship; Substance-Related Disorders; Thebaine | 1976 |
Some observations on the opiate peptides and schizophrenia.
Topics: Administration, Oral; Brain; Double-Blind Method; Endorphins; Forecasting; Humans; Naloxone; Naltrexone; Receptors, Opioid; Renal Dialysis; Schizophrenia | 1979 |
Methadone maintenance and narcotic blocking drugs. Appendix.
Topics: Administration, Oral; Cyclazocine; Drug Tolerance; Heroin Dependence; Humans; Injections, Subcutaneous; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Research; Substance Withdrawal Syndrome | 1977 |
Clinical pharmacology of narcotic antagonists.
Topics: Animals; Conditioning, Psychological; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Recurrence; Substance Withdrawal Syndrome; Substance-Related Disorders | 1978 |
Evolution of the National Academy of Sciences study of naltrexone.
Topics: Academies and Institutes; Clinical Trials as Topic; Cyclazocine; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Research Design; Research Support as Topic | 1976 |
Preclinical toxicity studies of naltrexone.
Topics: Administration, Oral; Animals; Body Weight; Colitis; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Fertility; Haplorhini; Injections, Subcutaneous; Lethal Dose 50; Male; Mice; Naloxone; Naltrexone; Rats; Reproduction; Rhinitis; Teratogens | 1976 |
Opiate antagonists and eating behavior in humans: a review.
Topics: Appetite Depressants; Dose-Response Relationship, Drug; Eating; Feeding and Eating Disorders; Feeding Behavior; Female; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Obesity | 1992 |
Drugs of abuse--opiates.
Topics: Central Nervous System; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Primary Health Care; Receptors, Opioid | 1990 |
Opioid antagonists: structure activity relationships.
Topics: Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Structure-Activity Relationship | 1990 |
Drug discrimination studies.
Topics: Analgesics, Opioid; Animals; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Stimulus; Macaca mulatta; Morphine; Nalorphine; Naloxone; Naltrexone; Pentazocine; Phenazocine; Phencyclidine; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
Behavioral significance of opioid peptides in relation to hippocampal function.
Topics: Animals; beta-Endorphin; Diprenorphine; Endorphins; Hippocampus; Learning; Memory; Naloxone; Naltrexone; Neurons, Afferent; Spatial Behavior | 1988 |
[Enkephalinergic regulation of cardiovascular centers].
Topics: Animals; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cats; Dextromoramide; Dogs; Enkephalin, Methionine; Enkephalins; Heart Rate; Medulla Oblongata; Naloxone; Naltrexone; Nervous System Physiological Phenomena; Pressoreceptors; Rats; Receptors, Opioid; Reflex; Reticular Formation; Sympathetic Nervous System; Vagus Nerve; Vasomotor System | 1985 |
Neurochemical correlates of opiate receptor regulation.
Topics: Animals; Brain Chemistry; Cells, Cultured; Endorphins; Ganglia, Spinal; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid | 1986 |
Multiple endogenous opiate and non-opiate analgesia systems: evidence of their existence and clinical implications.
Topics: Acupuncture Therapy; Analgesia; Animals; Cholecystokinin; Conditioning, Classical; Desipramine; Dimethyl Sulfoxide; Drug Interactions; Electroshock; Endorphins; Enkephalin, Leucine; Mecamylamine; Morphine; N-Methylscopolamine; Naloxone; Naltrexone; Norepinephrine; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Scopolamine; Scopolamine Derivatives; Serotonin; Spinal Cord | 1986 |
Stressor controllability and stress-induced analgesia.
Topics: Analgesia; Animals; Avoidance Learning; Electroshock; Injections, Spinal; Morphine; Naloxone; Naltrexone; Pain; Rats; Restraint, Physical; Sensory Thresholds; Stress, Physiological; Time Factors | 1986 |
Endocrine and metabolic effects of opiate antagonists.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Eating; Endocrine Glands; Female; Follicle Stimulating Hormone; Hormones; Humans; Hydrocortisone; Luteinizing Hormone; Male; Mice; Naloxone; Naltrexone; Rats; Vasopressins | 1984 |
[Narcotic withdrawal syndrome. Therapeutic methods].
Topics: Acupuncture Therapy; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Analgesia; Brain; Central Nervous System Agents; Clonidine; Endorphins; Humans; Methadone; Naloxone; Naltrexone; Narcotics; Receptors, Opioid; Substance Withdrawal Syndrome; Substance-Related Disorders | 1982 |
Opiate receptor pharmacology: mixed agonist/antagonist narcotics.
Topics: Analgesics, Opioid; Buprenorphine; Butorphanol; Endorphins; Humans; Nalbuphine; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Pentazocine; Receptors, Opioid | 1983 |
[Neuropeptide role in the etiology, pathogenesis and clinical aspects of mental diseases].
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Depressive Disorder; Drug Therapy, Combination; Endorphins; Enkephalins; Humans; Mental Disorders; Naloxone; Naltrexone; Nerve Tissue Proteins; Pituitary Hormones; Psychotropic Drugs; Schizophrenia; Substance-Related Disorders; Vasopressins | 1984 |
Autoanalgesia: opiate and non-opiate mechanisms.
Topics: Animals; Central Nervous System; Conditioning, Classical; Diazepam; Electroshock; Emotions; Endorphins; Fear; Hypophysectomy; Hypothalamus; Male; Mice; Naloxone; Naltrexone; Norepinephrine; Pain; Raphe Nuclei; Rats; Reaction Time; Receptors, Opioid; Serotonin; Spinal Cord | 1980 |
The role of narcotic antagonists in the rehabilitation of opiate addicts: a review of naltrexone.
Topics: Clinical Trials as Topic; Double-Blind Method; Endorphins; Humans; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Receptors, Opioid | 1980 |
The role of opioid peptides in memory and learning.
Topics: Amnesia; Animals; beta-Endorphin; Brain; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Humans; Learning; Memory; Naloxone; Naltrexone; Norepinephrine; Rats | 1980 |
Current status of preclinical research on disposition, pharmacokinetics, and metabolism of naltrexone.
Topics: Animals; Biotransformation; Humans; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Tissue Distribution | 1981 |
New and experimental therapeutic roles for naloxone and related opioid antagonists.
Topics: Alcohol Deterrents; Animals; Bipolar Disorder; Blood Pressure; Brain Ischemia; Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Respiration; Schizophrenia; Shock; Spinal Injuries | 1984 |
Minireview. Benzodiazepine-opiate antagonist interactions in relation to feeding and drinking behavior.
Topics: Animals; Benzodiazepines; Corpus Striatum; Drinking Behavior; Enkephalins; Feeding Behavior; Food Deprivation; Humans; Hyperphagia; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Reward; Thirst | 1983 |
The sequential use of clonidine and naltrexone in the treatment of opiate addicts.
Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1984 |
The physiology of opiate hedonic effects and the role of opioids in motivated behavior.
Topics: Animals; Conditioning, Operant; Electric Stimulation; Electroshock; Emotions; Endorphins; Feeding Behavior; Humans; Hypothalamus; Medial Forebrain Bundle; Morphine; Motivation; Naloxone; Naltrexone; Narcotics; Rats; Reward; Self Stimulation; Substance-Related Disorders | 1984 |
A review of parenteral sustained-release naltrexone systems.
Topics: Biodegradation, Environmental; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Drug Implants; Drug Industry; Naloxone; Naltrexone | 1981 |
Limitations on the antagonistic actions of opioid antagonists.
Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Cyclazocine; Macaca mulatta; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saimiri | 1982 |
Opiates and alcohol self-administration in animals.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Ethanol; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Receptors, Opioid; Reinforcement, Psychology; Self Administration | 1995 |
Opiate antagonists for the treatment of schizophrenia.
Topics: Hallucinations; Humans; Naloxone; Naltrexone; Schizophrenia | 1994 |
Efficacy of psychotropic drugs for reducing self-injurious behavior in the developmental disabilities.
Topics: Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Female; Humans; Intellectual Disability; Lithium Carbonate; Male; Naloxone; Naltrexone; Receptors, Dopamine; Self-Injurious Behavior; Treatment Outcome | 1993 |
Opiate detoxification protocols. A clinical manual.
Topics: Administration, Cutaneous; Clinical Protocols; Clonidine; Codeine; Female; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Psychiatric Status Rating Scales; Receptors, Opioid; Substance Withdrawal Syndrome | 1993 |
[Prevention of undesirable effects during the use of opiate antagonists].
Topics: Humans; Naloxone; Naltrexone; Narcotic Antagonists | 1993 |
Naltrexone: a case report of pruritus from an antipruritic.
Topics: Female; Humans; Injections, Subcutaneous; Middle Aged; Mycosis Fungoides; Naloxone; Naltrexone; Narcotic Antagonists; Pruritus; Skin Neoplasms | 1997 |
Rapid and ultrarapid opioid detoxification techniques.
Topics: Clinical Trials as Topic; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Research Design; Substance Withdrawal Syndrome | 1998 |
Nalmefene hydrochloride.
Topics: Clinical Trials as Topic; Drug Overdose; Half-Life; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics | 1999 |
Interactions between kappa opioid agonists and cocaine. Preclinical studies.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Discrimination Learning; Humans; Naloxone; Naltrexone; Receptors, Opioid, kappa; Self Administration | 2000 |
Opioid antagonists in the treatment of opioid-induced constipation and pruritus.
Topics: Clinical Trials as Topic; Constipation; Humans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pruritus; Quaternary Ammonium Compounds | 2001 |
Opioid antagonists for smoking cessation.
Topics: Buprenorphine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Smoking; Smoking Cessation | 2001 |
[Opioid detoxication under general anesthesia].
Topics: Anesthesia, General; Evidence-Based Medicine; Humans; Inactivation, Metabolic; Infusions, Intravenous; Monitoring, Physiologic; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic | 2002 |
[Cholestatic liver diseases].
Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruritics; Autoimmune Diseases; Bile Ducts; Cholagogues and Choleretics; Cholangiography; Cholangitis; Cholangitis, Sclerosing; Cholestasis; Cholestyramine Resin; Clinical Enzyme Tests; Diagnosis, Differential; Hepatitis, Autoimmune; Humans; Immunosuppression Therapy; Inflammatory Bowel Diseases; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Transplantation; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Plasmapheresis; Ursodeoxycholic Acid | 2004 |
Basal opioid receptor activity, neutral antagonists, and therapeutic opportunities.
Topics: Animals; Brain Chemistry; Calmodulin; Humans; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu; Signal Transduction | 2005 |
Opioid antagonists with minimal sedation for opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic | 2006 |
Role of opioid antagonists in the treatment of women with glucoregulation abnormalities.
Topics: Clinical Trials as Topic; Endorphins; Female; Humans; Hyperinsulinism; Insulin Resistance; Menopause; Naloxone; Naltrexone; Narcotic Antagonists; Obesity; Polycystic Ovary Syndrome | 2006 |
Antagonist treatment of opioid withdrawal translational low dose approach.
Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome | 2006 |
Opioid antagonists for smoking cessation.
Topics: Buprenorphine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Smoking; Smoking Cessation | 2006 |
Mu-opioid antagonists for opioid-induced bowel dysfunction.
Topics: Constipation; Defecation; Gastrointestinal Agents; Humans; Intestinal Diseases; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu | 2008 |
[News from the cochrane library: mu opioid antagonists for opioid-induced bowel dysfunction].
Topics: Analgesics, Opioid; Clinical Trials as Topic; Constipation; Gastrointestinal Transit; Humans; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu | 2008 |
Opioid receptors in the gastrointestinal tract.
Topics: Animals; Constipation; Gastrointestinal Tract; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid | 2009 |
Opioid antagonists with minimal sedation for opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome | 2009 |
Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal.
Topics: Anesthetics; Humans; Hypnotics and Sedatives; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome | 2010 |
The pharmacological treatment of opioid addiction--a clinical perspective.
Topics: Adrenergic Agonists; Analgesics, Opioid; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Social Support; Substance Withdrawal Syndrome | 2010 |
Antipruritic treatment with systemic μ-opioid receptor antagonists: a review.
Topics: Administration, Oral; Antipruritics; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Naloxone; Naltrexone; Pruritus; Randomized Controlled Trials as Topic; Receptors, Opioid, mu; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2010 |
The role of opioid receptor antagonists in the treatment of opioid-induced constipation: a review.
Topics: Analgesics, Opioid; Clinical Trials as Topic; Constipation; Delayed-Action Preparations; Drug Combinations; Humans; Laxatives; Naloxone; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds | 2010 |
Use of pure opioid antagonists for management of opioid-induced pruritus.
Topics: Adult; Analgesics, Opioid; Child; Humans; Infusions, Intravenous; Naloxone; Naltrexone; Narcotic Antagonists; Pruritus; Quality of Life; Quaternary Ammonium Compounds | 2011 |
Opioid receptor heteromers in analgesia.
Topics: Analgesia; Analgesics; Animals; Drug Antagonism; Drug Overdose; Humans; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Protein Multimerization; Protein Structure, Quaternary; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; United States | 2012 |
Opioid antagonists for pain.
Topics: Animals; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Pain | 2013 |
Pharmacotherapies for treating opioid use disorder.
Topics: Age Factors; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Prevalence; United States | 2013 |
Opioid antagonists for smoking cessation.
Topics: Buprenorphine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Smoking; Smoking Cessation; Tobacco Use Cessation Devices | 2013 |
Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and meta-analysis.
Topics: Alprostadil; Analgesics, Opioid; Benzofurans; Constipation; Female; Gastrointestinal Agents; Humans; Lubiprostone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperidines; Quaternary Ammonium Compounds; Receptors, Opioid, mu | 2013 |
Overview and treatment of opioid-induced constipation.
Topics: Analgesics, Opioid; Combined Modality Therapy; Constipation; Delayed-Action Preparations; Diet Therapy; Humans; Laxatives; Life Style; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds | 2013 |
Opioid antagonists.
Topics: Hospice Care; Humans; Internet; Naloxone; Naltrexone; Narcotic Antagonists; Palliative Care; Quaternary Ammonium Compounds | 2014 |
Detoxification treatments for opiate dependent adolescents.
Topics: Adolescent; Buprenorphine; Clonidine; Humans; Maintenance Chemotherapy; Naloxone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Dropouts; Randomized Controlled Trials as Topic | 2014 |
Constipation: opioid antagonists in people prescribed opioids.
Topics: Analgesics, Opioid; Constipation; Gastrointestinal Agents; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Treatment Outcome | 2015 |
Opioid Use Disorders.
Topics: Adolescent; Analgesics, Opioid; Buprenorphine; Drug Overdose; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders | 2016 |
Neuroscience in gambling policy and treatment: an interdisciplinary perspective.
Topics: Administrative Personnel; Appetite Depressants; Decision Making; Diagnostic and Statistical Manual of Mental Disorders; Disruptive, Impulse Control, and Conduct Disorders; Gambling; Harm Reduction; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neurosciences; Public Health | 2017 |
Opioid antagonists with minimal sedation for opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Clonidine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Non-Randomized Controlled Trials as Topic; Opioid-Related Disorders; Prospective Studies; Randomized Controlled Trials as Topic; Severity of Illness Index; Substance Withdrawal Syndrome | 2017 |
Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis.
Topics: Analgesics, Opioid; Gastrointestinal Agents; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Induced Constipation; Randomized Controlled Trials as Topic | 2019 |
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.
Topics: Constipation; Defecation; Female; Gastrointestinal Agents; Humans; Intestinal Diseases; Male; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Neoplasms; Opioid-Related Disorders; Oxycodone; Palliative Care; Piperidines; Quaternary Ammonium Compounds; Randomized Controlled Trials as Topic; Receptors, Opioid, mu | 2018 |
Naloxone and Maintenance Naltrexone as Novel and Effective Therapies for Immunotherapy-Induced Pruritus: A Case Report and Brief Literature Review.
Topics: Aged; Antibodies, Monoclonal, Humanized; Anus Neoplasms; Carcinoma, Squamous Cell; Female; Humans; Immunotherapy; Naloxone; Naltrexone; Narcotic Antagonists; Prognosis; Pruritus; Rectal Neoplasms | 2019 |
Topics: Acyclic Monoterpenes; Adipose Tissue; Adolescent; Adult; Aged; Aged, 80 and over; Air Pollutants; Air Pollutants, Occupational; Amino Acid Transport Systems; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Arthrobacter; Bacteria; Bacteriological Techniques; Benzaldehydes; Biodegradation, Environmental; Biofilms; Biological Transport; Biomarkers; Biomass; Bioreactors; Body Composition; Body Mass Index; Brassica; Brazil; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Caco-2 Cells; Cadmium; Calcium; Calcium Carbonate; Calcium Channels; Catalysis; Cell Degranulation; Cell Line; Cell Membrane; Chitosan; Chromatography, High Pressure Liquid; Chromium; Cobalt; Cohort Studies; Colony Count, Microbial; Composting; Copper; COVID-19; Cross-Sectional Studies; Cytoplasm; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diarrhea; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Drug Implants; Drug Stability; Drug Synergism; Electroplating; Endometrial Neoplasms; Endometrium; Environmental Monitoring; Environmental Restoration and Remediation; Estradiol; Estrogens; Feces; Female; Food Microbiology; Food Preservation; Fruit and Vegetable Juices; Gasotransmitters; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Glutathione; Gold; Graphite; Growth Hormone; Harm Reduction; Hot Temperature; Humans; Hydrocortisone; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydrogen-Ion Concentration; Ileum; Imidazoles; Injections, Intraperitoneal; Insecticides; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor I; Intestinal Absorption; Light; Lignin; Liver; Magnetics; Male; Manganese; Mast Cells; Melanoma; Membrane Potentials; Metals; Methadone; Microbial Viability; Microplastics; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Middle Aged; Mitochondrial Swelling; Molecular Dynamics Simulation; Monophenol Monooxygenase; Morocco; Naloxone; Naltrexone; Nanocomposites; Nanomedicine; Nanoparticles; Narcotic Antagonists; Neonicotinoids; Nitric Oxide; Nitro Compounds; Nitrogen; Nitrogen Compounds; Obesity; Obesity, Abdominal; Occupational Exposure; Ontario; Opiate Substitution Treatment; Opioid-Related Disorders; Oryza; Overweight; Oxidative Stress; Oxides; Oxygen; Perception; Photoelectron Spectroscopy; Plants; Plastics; Point Mutation; Polychlorinated Biphenyls; Polycyclic Aromatic Hydrocarbons; Potassium; Premenopause; Prodrugs; Prospective Studies; Protons; Pyrolysis; Qualitative Research; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resins, Synthetic; Rhodamines; Risk Factors; ROC Curve; Salmo salar; SARS-CoV-2; Seawater; Severity of Illness Index; Sewage; Social Media; Soil; Soil Microbiology; Soil Pollutants; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Staining and Labeling; Stainless Steel; Steel; Stress, Physiological; Substance Abuse Treatment Centers; Symporters; T-Lymphocytes; Toluene; Triclosan; Ultraviolet Rays; Waist Circumference; Waste Disposal, Fluid; Wastewater; Water Purification; Welding; X-Ray Diffraction; Young Adult | 2020 |
[Treatment of borderline personality disorder with opioid antagonists: buprenorphine, nalmefene, naloxone and naltrexone in the treatment of dissociative symptoms, self-mutilation and suicidal behavior].
Topics: Borderline Personality Disorder; Buprenorphine; Dissociative Disorders; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Observational Studies as Topic; Self Mutilation; Suicidal Ideation | 2020 |
Unconventional anxiety pharmacology in zebrafish: Drugs beyond traditional anxiogenic and anxiolytic spectra.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Aspirin; Behavior, Animal; Disease Models, Animal; Humans; Lysergic Acid Diethylamide; Motor Activity; Naloxone; Naltrexone; Nicotine; Zebrafish | 2021 |
Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.
Topics: Adult; Analgesics, Opioid; Child; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neoplasms; Opioid-Induced Constipation; Oxycodone; Palliative Care; Quaternary Ammonium Compounds; Substance Withdrawal Syndrome | 2022 |
Ligand-Free Signaling of G-Protein-Coupled Receptors: Relevance to μ Opioid Receptors in Analgesia and Addiction.
Topics: Analgesia; Analgesics, Opioid; Humans; Ligands; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Pain; Receptors, Opioid, mu | 2022 |
Treatment of dissociative symptoms with opioid antagonists: a systematic review.
Topics: Dissociative Disorders; Humans; Naloxone; Naltrexone; Narcotic Antagonists | 2023 |
65 trial(s) available for naltrexone and naloxone
Article | Year |
---|---|
Effect of an opiate antagonist on movement disorders.
Topics: Adult; Aged; Clinical Trials as Topic; Enkephalins; Humans; Huntington Disease; Middle Aged; Naloxone; Naltrexone; Parkinson Disease | 1978 |
NIDA's naltrexone research program.
Topics: Clinical Trials as Topic; Conditioning, Psychological; Cyclazocine; Drug Evaluation; Euphoria; Heroin; Heroin Dependence; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Research; Research Support as Topic; United States; United States Substance Abuse and Mental Health Services Administration | 1976 |
Effects of naltrexone on mood and neuroendocrine function in normal adult males.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Emotions; Humans; Libido; Luteinizing Hormone; Male; Naloxone; Naltrexone; Receptors, Opioid | 1978 |
Clinical evaluation of naltrexone treatment of opiate-dependent individuals. Report of the National Research Council Committee on Clinical Evaluation of Narcotic Antagonists.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Heroin; Heroin Dependence; Humans; Male; Methadone; Motivation; Naloxone; Naltrexone; Patient Compliance; Placebos; Research Design; Social Adjustment | 1978 |
The double-blind crossover trial design: how good is it for psychoactive drugs?
Topics: Adult; Cyclazocine; Double-Blind Method; Humans; Male; Naloxone; Naltrexone; Opioid-Related Disorders | 1979 |
EEG and other effects of naltrexone and heroin in man.
Topics: Auditory Threshold; Circadian Rhythm; Electroencephalography; Electrooculography; Heroin; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Time Factors | 1979 |
Controlled clinical study of naltrexone side effects comparing first-day doses and maintenance regimens.
Topics: Administration, Oral; Adolescent; Adult; Double-Blind Method; Drug Administration Schedule; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Naltrexone; Placebos; Self-Assessment | 1978 |
Naltrexone: physiological and psychological effects of single doses.
Topics: Blood Pressure; Body Temperature; Clinical Trials as Topic; Heart Rate; Humans; Male; Naloxone; Naltrexone; Placebos; Psychological Tests; Pupil; Respiration; Time Factors | 1976 |
Experiences with Naltrexone in Buffalo.
Topics: Administration, Oral; Clinical Trials as Topic; Consumer Behavior; Female; Heroin Dependence; Hospitalization; Humans; Male; Motivation; Naloxone; Naltrexone; New York; Outpatient Clinics, Hospital; Patient Dropouts | 1975 |
Narcotic antagonists: naltrexone progress report: introduction.
Topics: Clinical Trials as Topic; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Research | 1976 |
Clinical experience with naltrexone in a behavioral research study: an interim report.
Topics: Adult; Behavior; Clinical Trials as Topic; Counseling; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Illicit Drugs; Male; Middle Aged; Motivation; Naloxone; Naltrexone; Outpatient Clinics, Hospital; Patient Compliance; Patient Dropouts; Substance-Related Disorders | 1976 |
Comparison of two naltrexone treatment programs: naltrexone alone versus naltrexone plus behavior therapy.
Topics: Adult; Behavior Therapy; Black or African American; Black People; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Employment; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Narcotics; Patient Compliance; Spain; Students | 1976 |
Interim report on clinic intake and safety data collected from 17 NIDA-funded naltrexone studies.
Topics: Clinical Trials as Topic; Drug Administration Schedule; Humans; Naloxone; Naltrexone; Patient Dropouts; Statistics as Topic; Substance-Related Disorders | 1976 |
Evolution of the National Academy of Sciences study of naltrexone.
Topics: Academies and Institutes; Clinical Trials as Topic; Cyclazocine; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Research Design; Research Support as Topic | 1976 |
Varying clinical contexts for administering naltrexone.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Humans; Male; Middle Aged; Naloxone; Naltrexone; Patient Compliance; Patient Dropouts; Research Design; Statistics as Topic; Substance-Related Disorders; Time Factors | 1976 |
Patient response to naltrexone: issues of acceptance, treatment effects, and frequency of administration.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Patient Acceptance of Health Care; Patient Dropouts; Substance-Related Disorders; Time Factors | 1976 |
Naltrexone in methadone maintenance patients electing to become "drug free".
Topics: Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Patient Dropouts; Research Design | 1976 |
Comments and findings from a naltrexone double blind study.
Topics: Clinical Trials as Topic; Humans; Methadone; Naloxone; Naltrexone; Research Design; Statistics as Topic; Substance-Related Disorders | 1976 |
Factors influencing success in an antagonistic treatment program.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Patient Compliance; Patient Dropouts; Research Design | 1976 |
Clinical experiences with naltrexone in 370 detoxified addicts.
Topics: Clinical Trials as Topic; Cyclazocine; Drug Administration Schedule; Humans; Methadone; Naloxone; Naltrexone; Patient Compliance; Physicians; Placebos; Research Personnel; Substance-Related Disorders | 1976 |
Narcotic antagonist treatment of the criminal justice patient-institutional vs outpatient-including a 24 hour detox naltrexone induction regimen with oral medication.
Topics: Adolescent; Adult; Clinical Trials as Topic; Counseling; Drug Administration Schedule; Drug Evaluation; Female; Halfway Houses; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Outpatient Clinics, Hospital; Prisoners; Rehabilitation, Vocational; Research Design; Social Adjustment; Substance-Related Disorders | 1976 |
Use of narcotic antagonists (naltrexone) in an addiction treatment program.
Topics: Adolescent; Adult; Attitude; Clinical Trials as Topic; Drug Evaluation; Humans; Male; Middle Aged; Naloxone; Naltrexone; Patient Compliance; Personality Inventory; Self Medication; Substance-Related Disorders; Time Factors | 1976 |
Naltrexone and cyclazocine. A controlled treatment study.
Topics: Administration, Oral; Adult; Cyclazocine; Double-Blind Method; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Placebos; Self-Assessment | 1977 |
Phase II clinical trials of buprenorphine: detoxification and induction onto naltrexone.
Topics: Adult; Blood Pressure; Buprenorphine; Double-Blind Method; Female; Humans; Male; Methadone; Methoxyhydroxyphenylglycol; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1992 |
Antiretroviral activity of naloxone and naltrexone.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; HIV-1; Humans; Killer Cells, Natural; Naloxone; Naltrexone | 1991 |
Opioid antagonist challenges in buprenorphine maintained patients.
Topics: Administration, Sublingual; Adult; Buprenorphine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Infusions, Intravenous; Male; Methadone; Naloxone; Naltrexone; Substance Withdrawal Syndrome | 1990 |
Beta-endorphin disregulation in autistic and self-injurious behavior: a neurodevelopmental hypothesis.
Topics: Adult; Autistic Disorder; beta-Endorphin; Clinical Trials as Topic; Developmental Disabilities; Homeostasis; Humans; Male; Naloxone; Naltrexone | 1988 |
Duration of antagonistic effects of nalmefene and naloxone in opiate-induced sedation for emergency department procedures.
Topics: Adolescent; Adult; Aged; Attention; Consciousness; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Meperidine; Middle Aged; Multicenter Studies as Topic; Naloxone; Naltrexone; Random Allocation | 1989 |
Effects of naloxone and naltrexone on self-injury: a double-blind, placebo-controlled analysis.
Topics: Autistic Disorder; Child; Clinical Trials as Topic; Conditioning, Operant; Double-Blind Method; Extinction, Psychological; Female; Half-Life; Humans; Naloxone; Naltrexone; Reinforcement Schedule; Self Mutilation | 1989 |
Rapid detoxification from opioid dependence.
Topics: Buprenorphine; Clinical Trials as Topic; Double-Blind Method; Humans; Naloxone; Naltrexone; Opioid-Related Disorders; Placebos; Substance Withdrawal Syndrome | 1989 |
Nontolerance to the opioid antagonism of naltrexone.
Topics: Adult; Arousal; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Euphoria; Female; Heart Rate; Heroin Dependence; Humans; Male; Middle Aged; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1985 |
Naltrexone-induced dysphoria in former opioid addicts.
Topics: Adult; Affective Symptoms; Ejaculation; Emotions; Humans; Libido; Male; Motor Activity; Naloxone; Naltrexone; Opioid-Related Disorders; Receptors, Opioid | 1985 |
Antagonism of morphine-induced respiratory depression with nalmefene.
Topics: Adult; Carbon Dioxide; Depression, Chemical; Humans; Male; Middle Aged; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Partial Pressure; Respiration; Time Factors | 1988 |
Reduction of hyperinsulinemia and insulin resistance by opiate receptor blockade in the polycystic ovary syndrome with acanthosis nigricans.
Topics: Acanthosis Nigricans; Adolescent; Adult; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Naloxone; Naltrexone; Narcotic Antagonists; Polycystic Ovary Syndrome | 1987 |
Naltrexone and human eating behavior: a dose-ranging inpatient trial in moderately obese men.
Topics: Adult; Basal Metabolism; Body Weight; Clinical Trials as Topic; Drug Administration Schedule; Energy Intake; Feeding Behavior; Humans; Male; Naloxone; Naltrexone; Obesity | 1985 |
The role of the National Institute on Drug Abuse in the development of naltrexone.
Topics: Aftercare; Animals; Carcinogens; Clinical Trials as Topic; Clonidine; Drug Administration Schedule; Drug and Narcotic Control; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Motivation; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Compliance; Rats; United States; United States Substance Abuse and Mental Health Services Administration | 1984 |
The role of narcotic antagonists in the rehabilitation of opiate addicts: a review of naltrexone.
Topics: Clinical Trials as Topic; Double-Blind Method; Endorphins; Humans; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Receptors, Opioid | 1980 |
Action of naloxone and naltrexone in different types of psychoses.
Topics: Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Endorphins; Humans; Naloxone; Naltrexone; Psychotic Disorders; Receptors, Opioid; Schizophrenia | 1981 |
New and experimental therapeutic roles for naloxone and related opioid antagonists.
Topics: Alcohol Deterrents; Animals; Bipolar Disorder; Blood Pressure; Brain Ischemia; Clinical Trials as Topic; Humans; Lung Diseases, Obstructive; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Respiration; Schizophrenia; Shock; Spinal Injuries | 1984 |
Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: evidence for noradrenergic hyperactivity.
Topics: Adult; Blood Pressure; Brain; Female; Humans; Kinetics; Male; Methadone; Methoxyhydroxyphenylglycol; Naloxone; Naltrexone; Narcotics; Norepinephrine; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Naloxone and naltrexone in mental illness and tardive dyskinesia.
Topics: Animals; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Endorphins; Humans; Mood Disorders; Naloxone; Naltrexone; Rats; Schizophrenia | 1982 |
Assessment of naltrexone in the treatment of schizophrenia.
Topics: Adult; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Male; Naloxone; Naltrexone; Schizophrenia | 1981 |
Naltrexone in chronic schizophrenia. Results of a clinical trial.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Psychiatric Status Rating Scales; Schizophrenia | 1980 |
Naltrexone treatment of heroin addiction: efficacy and safety in a double-blind dosage comparison.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Naltrexone | 1981 |
Clonidine and naltrexone. A safe, effective, and rapid treatment of abrupt withdrawal from methadone therapy.
Topics: Adult; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1982 |
Aversive effects of naltrexone in subjects not dependent on opiates.
Topics: Adult; Affect; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Motivation; Naloxone; Naltrexone | 1981 |
Operant analysis of human heroin self-administration and the effects of naltrexone.
Topics: Adult; Conditioning, Operant; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Placebos; Self Administration | 1981 |
Naltrexone treatment restores menstrual cycles in patients with weight loss-related amenorrhea.
Topics: Administration, Oral; Amenorrhea; Body Mass Index; Dose-Response Relationship, Drug; Estrogen Replacement Therapy; Estrogens; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Menstrual Cycle; Naloxone; Naltrexone; Narcotic Antagonists; Progestins; Weight Loss | 1995 |
Comparison of potency and duration of action of nalmefene and naloxone.
Topics: Adult; Double-Blind Method; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Reference Values; Time Factors | 1994 |
Efficacy of methylnaltrexone versus naloxone for reversal of morphine-induced depression of hypoxic ventilatory response.
Topics: Adult; Double-Blind Method; Humans; Hypoxia; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Respiration | 1994 |
Efficacy and safety of two new methods of rapid intravenous detoxification in heroin addicts previously treated without success.
Topics: Adult; Conscious Sedation; Critical Care; Heroin Dependence; Humans; Inactivation, Metabolic; Infusions, Intravenous; Length of Stay; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Recurrence; Substance Withdrawal Syndrome; Treatment Failure | 1997 |
Longer occupancy of opioid receptors by nalmefene compared to naloxone as measured in vivo by a dual-detector system.
Topics: Adult; Analgesics, Opioid; Brain; Carbon Radioisotopes; Cross-Over Studies; Female; Fentanyl; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Time Factors; Tomography, Emission-Computed | 1997 |
Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Dynorphins; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Prolactin; Receptors, Dopamine; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Characteristics; Time Factors | 1999 |
Opiate detoxification under anesthesia: no apparent benefit but suppression of thyroid hormones and risk of pulmonary and renal failure.
Topics: Acute Kidney Injury; Adult; Anesthesia; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Respiratory Insufficiency; Substance Withdrawal Syndrome; Thyroid Hormones | 1999 |
Double-blind, randomized study of nalmefene and naloxone in emergency department patients with suspected narcotic overdose.
Topics: Adult; Double-Blind Method; Drug Overdose; Emergency Treatment; Humans; Injections, Intravenous; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neurologic Examination; Respiration; Time Factors; Treatment Outcome | 1999 |
Rapid opioid detoxification during general anesthesia: a review of 20 patients.
Topics: Adult; Anesthesia, General; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1999 |
Rapid opiate detoxication in outpatient treatment: relationship with naltrexone compliance.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; GABA Agents; Heroin Dependence; Humans; Inactivation, Metabolic; Ketoprofen; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxazepam; Patient Compliance; Substance Withdrawal Syndrome; Treatment Outcome | 2000 |
Plasma catecholamines during an ultrarapid heroin detoxification.
Topics: Adult; Analysis of Variance; Catecholamines; Drug Administration Routes; Drug Therapy, Combination; Female; Heroin; Heroin Dependence; Humans; Inactivation, Metabolic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome; Systole; Treatment Outcome | 2000 |
Influence of opioids in hypothalamic nuclei on cold thermogenesis of lean and obese LA/N-cp rats.
Topics: Animals; Cold Temperature; Enkephalin, Leucine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Obesity; Opioid Peptides; Oxygen Consumption; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Stress, Physiological; Thermogenesis | 1994 |
Treatment of pruritus with topically applied opiate receptor antagonist.
Topics: Administration, Topical; Adult; Aged; Cross-Over Studies; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Pilot Projects; Prospective Payment System; Pruritus | 2007 |
Reversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexone.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Humans; Infusions, Intravenous; Male; Middle Aged; Miosis; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Quaternary Ammonium Compounds; Remifentanil; Treatment Outcome; Urinary Bladder; Urinary Retention; Urination | 2007 |
Cocaine use reduction with buprenorphine (CURB): rationale, design, and methodology.
Topics: Administration, Sublingual; Adolescent; Adult; Aged; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Treatment Outcome; Young Adult | 2013 |
A randomized, double-blind evaluation of buprenorphine taper duration in primary prescription opioid abusers.
Topics: Adult; Buprenorphine; Cognitive Behavioral Therapy; Combined Modality Therapy; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Psychiatric Status Rating Scales; Severity of Illness Index; Time Factors; Treatment Outcome; Young Adult | 2013 |
Effect of methylnaltrexone and naloxone on esophageal motor function in man.
Topics: Adolescent; Adult; Cross-Over Studies; Esophageal pH Monitoring; Esophageal Sphincter, Lower; Female; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Single-Blind Method; Young Adult | 2017 |
Naloxone and nalmefene absorption delivered by hollow microneedles compared to intramuscular injection.
Topics: Analgesics, Opioid; Animals; Cross-Over Studies; Dogs; Humans; Injections, Intramuscular; Naloxone; Naltrexone; Narcotic Antagonists | 2022 |
1292 other study(ies) available for naltrexone and naloxone
Article | Year |
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Quantum chemical studies of N-substituent variation in the oxymorphone series of opiate narcotics.
Topics: Analgesics, Opioid; Animals; Hydromorphone; In Vitro Techniques; Mice; Molecular Conformation; Oxymorphone; Quantum Theory; Rats; Structure-Activity Relationship; Swine; Thermodynamics | 1978 |
Electrophilic opioid ligands. Oxygen tethered alpha-methylene-gamma-lactone, acrylate, isothiocyanate, and epoxide derivatives of 6 beta-naltrexol.
Topics: Acrylates; Animals; Binding Sites; Brain; Endorphins; Epoxy Compounds; Guinea Pigs; Lactones; Ligands; Naltrexone; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Thiocyanates | 1992 |
O3-(2-carbomethoxyallyl) ethers of opioid ligands derived from oxymorphone, naltrexone, etorphine, diprenorphine, norbinaltorphimine, and naltrindole. Unexpected O3-dealkylation in the opioid radioligand displacement assay.
Topics: Alkylation; Animals; Brain; Diprenorphine; Drug Stability; Ethers; Etorphine; Guinea Pigs; Indoles; Methacrylates; Molecular Structure; Morphinans; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Phenols; Radioligand Assay; Receptors, Opioid; Tritium | 1992 |
Electrophilic gamma-lactone kappa-opioid receptor probes. Analogues of 2'-hydroxy-2-tetrahydrofurfuryl-5,9-dimethyl-6,7-benzomorphan diastereomers.
Topics: Animals; Benzomorphans; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Guinea Pigs; Molecular Conformation; Molecular Structure; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism; Structure-Activity Relationship | 1991 |
Conjugate addition ligands of opioid antagonists. Methacrylate esters and ethers of 6 alpha- and 6 beta-naltrexol.
Topics: Animals; Benzomorphans; Binding, Competitive; Cattle; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Esters; Ethers; In Vitro Techniques; Ligands; Methacrylates; Naltrexone; Receptors, Opioid; Structure-Activity Relationship | 1990 |
Photoactivatable opiate derivatives as irreversible probes of the mu-opioid receptor.
Topics: Affinity Labels; Animals; Azides; Azo Compounds; Binding Sites; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, mu; Structure-Activity Relationship | 1990 |
Synthesis and biological evaluation of 14-alkoxymorphinans. 2. (-)-N-(cyclopropylmethyl)-4,14-dimethoxymorphinan-6-one, a selective mu opioid receptor antagonist.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Mice; Morphinans; Narcotic Antagonists; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1989 |
Structure-activity relationships for drugs binding to the agonist and antagonist states of the primary morphine receptor.
Topics: Algorithms; Animals; Kinetics; Models, Molecular; Narcotic Antagonists; Narcotics; Protein Conformation; Rats; Receptors, Opioid; Structure-Activity Relationship | 1988 |
Long-acting opiate agonists and antagonists: 14-hydroxydihydromorphinone hydrazones.
Topics: Analgesics, Opioid; Animals; Brain; Delayed-Action Preparations; Hydrazones; Hydromorphone; In Vitro Techniques; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oxymorphone; Rats; Receptors, Opioid | 1980 |
Allylprodine analogues as receptor probes. Evidence that phenolic and nonphenolic ligands interact with different subsites on identical opioid receptors.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Phenols; Piperidines; Reaction Time; Receptors, Opioid; Structure-Activity Relationship | 1981 |
Common anionic receptor site hypothesis: its relevance to the antagonist action of naloxone.
Topics: Animals; Anions; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotics; Rats; Receptors, Opioid | 1982 |
Different receptor sites mediate opioid agonism and antagonism.
Topics: Animals; Binding Sites; Kinetics; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Structure-Activity Relationship | 1983 |
Analgesic narcotic antagonists. 9. 6-Methylene-8 beta-alkyl-N-(cycloalkylmethyl)-3-hydroxy- or -methoxymorphinans.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Haplorhini; Humans; Mice; Morphinans; Morphine Dependence; Narcotic Antagonists; Rats; Reaction Time; Substance Withdrawal Syndrome | 1981 |
Some 14 beta-substituted analogues of N-(cyclopropylmethyl)normorphine.
Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Morphine Derivatives; Muscle, Smooth; Vas Deferens | 1981 |
kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system.
Topics: Adenylyl Cyclases; Aged; Amino Acid Sequence; Base Sequence; Central Nervous System; Chromosome Mapping; Chromosomes, Human, Pair 8; Cloning, Molecular; DNA, Complementary; Exons; Genomic Library; Humans; In Situ Hybridization; Ligands; Middle Aged; Molecular Sequence Data; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Tissue Distribution | 1995 |
Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.
Topics: Animals; Diarrhea; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Intestinal Diseases; Male; Mice; Piperidines; Radioligand Assay; Receptors, Opioid, mu; Structure-Activity Relationship | 1994 |
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Somatostatin; RNA, Messenger; Sequence Homology, Amino Acid; Substrate Specificity; Tissue Distribution | 1993 |
Structure-activity relationships of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine antagonists for mu- and kappa-opioid receptors.
Topics: Analgesia; Animals; Diuresis; Furans; Male; Mice; Molecular Structure; Morphine; Piperidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 1993 |
3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity.
Topics: Analgesia; Animals; Appetite Depressants; Cyclohexanes; Diuresis; Eating; Endorphins; Guinea Pigs; Male; Mice; Molecular Structure; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Zucker; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 1993 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Elucidation of the bioactive conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine class of mu-opioid receptor antagonists.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Molecular Conformation; Piperidines; Radioligand Assay; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2006 |
Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Molecular Structure; Pyrazines; Pyridines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2006 |
Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia.
Topics: Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; Animals; Chemokine CCL5; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Transgenic; Morphine; Naloxone; Pain; Pain Measurement; Receptors, CCR5 | 2007 |
Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; CHO Cells; Cricetinae; Cricetulus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Morphinans; Nalbuphine; Naloxone; Naltrexone; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
The influence of esters and carboxylic acids as the N-substituent of opioids. Part 1: Benzomorphans.
Topics: Analgesics, Opioid; Benzomorphans; Carboxylic Acids; Esters; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.
Topics: Amides; Analgesics, Opioid; Humans; Protein Binding; Receptors, Opioid; Structure-Activity Relationship; Tramadol | 2009 |
Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists.
Topics: Amino Acid Sequence; Analgesics; Analgesics, Opioid; Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Drug Design; Ligands; Models, Molecular; Molecular Sequence Data; Morphinans; Morphine; Naltrexone; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sequence Alignment; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in enantiomeric 5-(3-hydroxyphenyl)morphans.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Cyclopropanes; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Magnetic Resonance Spectroscopy; Morphinans; Receptors, Opioid, mu; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Structure-Activity Relationship | 2011 |
Generation of novel radiolabeled opiates through site-selective iodination.
Topics: Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Iodine Radioisotopes; Molecular Structure; Neurotransmitter Agents; Oxymorphone; Radioligand Assay; Receptors, Opioid | 2011 |
Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. Part 2: Synthesis of novel triplet drugs with the epoxymethano structure (capped homotriplet).
Topics: Analgesics, Opioid; Animals; Bridged-Ring Compounds; Mice; Models, Molecular; Nitriles; Nociception; Nociceptive Pain; Pain Measurement; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sesquiterpenes; Tosyl Compounds | 2011 |
Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.
Topics: Amides; Analgesics; Animals; Behavior, Animal; Brain; Cell Line; Chemistry Techniques, Synthetic; Exons; Male; Mice; Opiate Alkaloids; Protein Isoforms; Protein Structure, Tertiary; Receptors, Opioid, mu; Structure-Activity Relationship | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivity.
Topics: Animals; Behavior, Animal; Chemistry Techniques, Synthetic; CHO Cells; Cricetinae; Cricetulus; Drug Design; Male; Mice; Models, Molecular; Naltrexone; Protein Conformation; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substrate Specificity | 2013 |
Opioids and efflux transporters. Part 4: influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Conformation; Morphinans; Structure-Activity Relationship | 2014 |
Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor.
Topics: Animals; Binding, Competitive; Buprenorphine; CHO Cells; Cricetulus; Fluorescent Dyes; HEK293 Cells; Humans; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Radioligand Assay; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2015 |
Accumulation of cGMP in striatum of rats injected with narcotic analgesics: antagonism by naltrexone.
Topics: Analgesics, Opioid; Animals; Corpus Striatum; Cyclic GMP; Isomerism; Kinetics; Male; Naloxone; Naltrexone; Rats; Time Factors | 1976 |
Behavioral effects of narcotic analgesics administered alone or in combination with narcotic antagonists.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; Drug Interactions; Electroshock; Haplorhini; Macaca fascicularis; Methadone; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Time Factors | 1976 |
Development of Chronomers for narcotic antagonists.
Topics: Animals; Biodegradation, Environmental; Drug Implants; Hydrogen-Ion Concentration; Kinetics; Morphine; Naloxone; Naltrexone; Polymers; Rats; Reaction Time | 1975 |
Drug release from o/w/o multiple emulsion systems.
Topics: Emulsions; Hydrogen-Ion Concentration; Naloxone; Naltrexone; Technology, Pharmaceutical; Thymol | 1978 |
Opiate-receptor mediated changes in monoamine synthesis in rat brain.
Topics: Animals; Behavior, Animal; Biogenic Amines; Brain; Catalepsy; Endorphins; Humans; Injections, Intraventricular; Male; Morphine; Naloxone; Naltrexone; Rats; Receptors, Opioid; Time Factors | 1978 |
Analeptic and antianaleptic effects of naloxone and naltrexone in rabbits.
Topics: Amphetamine; Anesthesia; Animals; Central Nervous System Stimulants; Male; Motor Activity; Naloxone; Naltrexone; Pentobarbital; Rabbits; Reflex; Thyrotropin-Releasing Hormone; Time Factors | 1978 |
Letter: Treatment of accidental naltrexone-induced withdrawal.
Topics: Adult; Humans; Hydromorphone; Male; Methadone; Naloxone; Naltrexone; Substance Withdrawal Syndrome | 1976 |
Naltrexone in a behavioral treatment program.
Topics: Behavior; Conditioning, Psychological; Extinction, Psychological; Humans; Hydromorphone; Injections; Naloxone; Naltrexone; Remission, Spontaneous; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1976 |
Orientation of the oxygen atom at C-6 as a determinant of agonistic activity in the oxymorphone series.
Topics: Animals; Guinea Pigs; Hydromorphone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxygen; Oxymorphone; Structure-Activity Relationship | 1977 |
Chloroxymorphamine, and opioid receptor site-directed alkylating agent having narcotic agonist activity.
Topics: Alkylating Agents; Animals; Chlorambucil; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Hydromorphone; In Vitro Techniques; Morphine; Naloxone; Naltrexone; Nitrogen Mustard Compounds; Norepinephrine; Oxymorphone; Phenoxybenzamine; Receptors, Opioid | 1979 |
Unreinforced self-injections: effects on rituals and outcome in heroin addicts.
Topics: Extinction, Psychological; Follow-Up Studies; Heroin Dependence; Humans; Hydromorphone; Male; Naloxone; Naltrexone; Reinforcement, Psychology; Research Design; Self Administration | 1979 |
Historical trends in naltrexone research.
Topics: Heroin Dependence; History, 20th Century; Humans; Naloxone; Naltrexone; Research; United States | 1978 |
Naltrexone: the clinical investigator's dilemma.
Topics: Adolescent; Adult; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Patient Dropouts; Research Design; Social Adjustment; United States | 1978 |
The future of naltrexone.
Topics: Adolescent; Adult; Endorphins; Female; Forecasting; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Patient Compliance; United States | 1978 |
Evidence for a mutagenic effect of the narcotic antagonist, naltrexone, in germ cells of Drosophila.
Topics: Animals; Drosophila melanogaster; Drug Evaluation, Preclinical; Female; Genes, Lethal; Genes, Recessive; Male; Mutagens; Naloxone; Naltrexone; Spermatozoa; X Chromosome | 1979 |
Plasma naltrexone kinetics after intravenous bolus administration in dogs and monkeys.
Topics: Animals; Chromatography, Gas; Dogs; Female; Haplorhini; Hydrolysis; Injections, Intravenous; Kinetics; Male; Mass Spectrometry; Models, Biological; Naloxone; Naltrexone | 1979 |
Opiate antagonists can inhibit mammary tumor growth in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Endorphins; Female; Mammary Neoplasms, Experimental; Naloxone; Naltrexone; Rats | 1979 |
Prevention by naltrexone of tolerance to the rate-decreasing effects of morphine on schedule-controlled responding in the pigeon.
Topics: Animals; Columbidae; Conditioning, Operant; Drug Tolerance; Male; Morphine; Naloxone; Naltrexone; Reinforcement Schedule; Time Factors | 1979 |
Naltrexone and behavior therapy for heroin addiction.
Topics: Adult; Behavior Therapy; California; Dose-Response Relationship, Drug; Ethnicity; Follow-Up Studies; Heroin; Heroin Dependence; Humans; Naloxone; Naltrexone | 1979 |
Naltrexone, 6 beta-naltrexol and 2-hydroxy-3-methoxy-6 beta-naltrexol plasma levels in schizophrenic patients after large oral doses of naltrexone.
Topics: Humans; Middle Aged; Naloxone; Naltrexone; Schizophrenia | 1979 |
Heroin and naltrexone effects on pituitary-gonadal hormones in man: tolerance and supersensitivity.
Topics: Adult; Heroin; Heroin Dependence; Humans; Luteinizing Hormone; Male; Naloxone; Naltrexone; Prolactin; Testosterone | 1979 |
Modification of treatment compliance as a function of contingent payment manipulations.
Topics: Adult; Heroin Dependence; Humans; Naloxone; Naltrexone; Patient Compliance; Reinforcement, Psychology | 1979 |
Genetic screening of compounds used in drug abuse treatment. I. Naltrexone hydrochloride.
Topics: Animals; Bacteria; Bone Marrow Cells; Cells, Cultured; In Vitro Techniques; Mice; Mice, Inbred ICR; Microsomes, Liver; Mutagens; Naloxone; Naltrexone; Neurospora crassa; Rats; Yeasts | 1978 |
The clinical usefulness of narcotic antagonists: implications of behavioral research.
Topics: Aftercare; Behavior Therapy; Conditioning, Operant; Cyclazocine; Extinction, Psychological; Heroin; Heroin Dependence; Hospitalization; Humans; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Patient Dropouts; Reinforcement, Psychology; Research Design; Self-Assessment | 1975 |
Analysis and modification of opiate reinforcement.
Topics: Adult; Aftercare; Behavior Therapy; Boston; Cyclazocine; Follow-Up Studies; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Patient Dropouts; Reinforcement, Psychology; Token Economy | 1976 |
Opiate antagonists and the modification of heroin self-administration behavior in man: an experimental study.
Topics: Adult; Aftercare; Behavior Therapy; Boston; Conditioning, Operant; Evaluation Studies as Topic; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Research Design; Satiation; Token Economy | 1976 |
Naltrexone-induced hypothermia in the rat.
Topics: Animals; Body Temperature Regulation; Dose-Response Relationship, Drug; Humans; Hypothermia; Morphine; Naloxone; Naltrexone; Placebos; Rats; Receptors, Opioid; Substance Withdrawal Syndrome; Substance-Related Disorders | 1976 |
A method for site selectivity analysis applied to opiate receptors.
Topics: Animals; In Vitro Techniques; Morphine Derivatives; Naloxone; Naltrexone; Rats; Receptors, Opioid | 1976 |
Naltrexone in the management of heroin addiction: critique of the rationale.
Topics: Conditioning, Psychological; Heroin Dependence; Humans; Impulsive Behavior; Motivation; Naloxone; Naltrexone; Peptides; Receptors, Opioid | 1976 |
The effects of naltrexone in the chronic spinal dog and acute spinal cat; possible interaction with naturally-occurring morphine-like agonists.
Topics: Animals; Brain; Cats; Cyclazocine; Dogs; Drug Interactions; Morphine Derivatives; Nalorphine; Naloxone; Naltrexone; Receptors, Opioid; Spinal Cord | 1976 |
Endogenous opiate receptor ligand: electrically induced release in the guinea pig ileum.
Topics: Electric Stimulation; Ileum; Ligands; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nerve Tissue Proteins; Neuromuscular Junction; Peptides; Receptors, Opioid; Stereoisomerism | 1977 |
Behavioural dissociation of the enkephalinergic systems of nucleus accumbens and nucleus caudatus.
Topics: Animals; Brain; Caudate Nucleus; Enkephalins; Globus Pallidus; Male; Morphine; Naloxone; Naltrexone; Olfactory Bulb; Oligopeptides; Rats; Receptors, Opioid; Stereotaxic Techniques | 1977 |
Opioid peptides and opiates differ in receptor selectivity.
Topics: Animals; Brain; Dextrorphan; Endorphins; Enkephalins; Isomerism; Levorphanol; Methadone; Morphine; Naloxone; Naltrexone; Rats; Receptors, Opioid | 1977 |
[Receptor occupation and pharmacological activity as demonstrated on opiates (author's transl)].
Topics: Animals; Binding Sites; Endorphins; Mice; Naloxone; Naltrexone; Receptors, Opioid; Tritium | 1977 |
Stimulus effects of delta(9)-THC and its interaction with naltrexone and catecholamine blockers in rats.
Topics: Animals; Catecholamines; Columbidae; Dronabinol; Drug Interactions; Injections, Intraperitoneal; Male; Naloxone; Naltrexone; Rats; Receptors, Adrenergic, alpha | 1977 |
Methadone maintenance and narcotic blocking drugs.
Topics: Aftercare; Cyclazocine; Extinction, Psychological; Heroin Dependence; Hospitalization; Humans; Levallorphan; Methadone; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Psychotherapy; Receptors, Opioid | 1977 |
Regulation of prolactin release by endogenous opiates.
Topics: Animals; Endorphins; Female; Hypothalamus; Male; Naloxone; Naltrexone; Pituitary Gland; Prolactin; Rats; Receptors, Opioid | 1977 |
6beta-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan(chlornaltrexamine) a potent opioid receptor alkylating agent with ultralong narcotic antagonist actitivty.
Topics: Alkylating Agents; Analgesia; Binding, Competitive; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nitrogen Mustard Compounds; Receptors, Opioid | 1978 |
Phospholipid changes in synaptic membranes by lipolytic enzymes and subsequent restoration of opiate binding with phosphatidylserine.
Topics: Animals; Carboxy-Lyases; Dihydromorphine; Naloxone; Naltrexone; Phosphatidylethanolamines; Phosphatidylserines; Phospholipases; Phospholipids; Rats; Receptors, Opioid; Structure-Activity Relationship; Synaptic Membranes | 1978 |
Permanent alterations of central opiate systems as a result of chronic opiate antagonism during infancy in rats.
Topics: Animals; Animals, Newborn; Drinking Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid; Time Factors | 1978 |
Synthesis and pharmacologic characterization of an alkylating analogue (chlornaltrexamine) of naltrexone with ultralong-lasting narcotic antagonist properties.
Topics: Alkylating Agents; Analgesics; Animals; Humans; In Vitro Techniques; Male; Mice; Molecular Conformation; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Nitrogen Mustard Compounds; Rats; Receptors, Opioid; Time Factors | 1979 |
A history of the development of narcotic antagonists for the treatment of narcotic addiction.
Topics: Animals; Cyclazocine; Drug Tolerance; Euphoria; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Substance-Related Disorders | 1978 |
Update of naltrexone treatment.
Topics: Adult; Conditioning, Psychological; Female; Humans; Male; Methadone; Naloxone; Naltrexone; Narcotics; Receptors, Opioid; Social Adjustment; Substance Withdrawal Syndrome; Substance-Related Disorders | 1978 |
Naltrexone in the treatment of opiate dependence.
Topics: Adolescent; Adult; Follow-Up Studies; Forecasting; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Narcotics; New York City; Psychotherapy; Receptors, Opioid; Recurrence; Substance Withdrawal Syndrome; Substance-Related Disorders | 1978 |
The development of sustained action preparations of narcotic antagonists.
Topics: Animals; Delayed-Action Preparations; Drug Implants; Humans; Naloxone; Naltrexone; Narcotics; Receptors, Opioid; Research Design; Substance-Related Disorders | 1978 |
Naloxone and naltrexone: actions and interactions at an opiate drug receptor on frog skeletal muscle fibers.
Topics: Action Potentials; Animals; Anura; Electrodes; In Vitro Techniques; Membrane Potentials; Muscles; Naloxone; Naltrexone; Potassium; Rana pipiens; Receptors, Opioid | 1979 |
Research and development of naltrexone: a new narcotic antagonist.
Topics: Financing, Government; Heroin Dependence; Humans; Legislation, Drug; Naloxone; Naltrexone; Receptors, Opioid; Research; United States | 1979 |
Hormonal and other effects of naltrexone in normal men.
Topics: Adrenocorticotropic Hormone; Adult; Body Temperature; Humans; Hydrocortisone; Luteinizing Hormone; Male; Naloxone; Naltrexone; Pain; Prolactin; Respiration; Testosterone | 1979 |
Alterations in brain opiate receptors in Parkinson's disease.
Topics: Aged; Caudate Nucleus; Corpus Striatum; Dopamine; Humans; Middle Aged; Naloxone; Naltrexone; Parkinson Disease; Putamen; Receptors, Dopamine; Receptors, Opioid | 1979 |
Psychiatric implications of endorphin research.
Topics: Animals; Avoidance Learning; Behavior, Animal; Chronic Disease; Endorphins; Humans; Mental Disorders; Naloxone; Naltrexone; Rats; Receptors, Opioid; Schizophrenia | 1979 |
A gas-liquid chromatographic method for the determination of naltrexone and beta-naltrexol in human urine.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Etorphine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Naloxone; Naltrexone; Solvents | 1975 |
Clinical outcome with naltrexone.
Topics: Follow-Up Studies; Humans; Male; Naloxone; Naltrexone; Substance-Related Disorders; Time Factors | 1978 |
Analgesia to pain stimuli in schizophrenics and its reversal by naltrexone.
Topics: Adult; Electric Stimulation; Evoked Potentials; Female; Humans; Male; Naloxone; Naltrexone; Pain; Schizophrenia | 1979 |
Endogenous opioids participate in the regulation of the hypothalamus-pituitary-luteinizing hormone axis and testosterone's negative feedback control of luteinizing hormone.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Morphine; Naloxone; Naltrexone; Pituitary Gland; Rats; Testosterone | 1979 |
Failure of beta-endorphin antiserum, naloxone, and naltrexone to alter physiologic growth hormone and insulin secretion.
Topics: Animals; Antibodies; Camelus; Endorphins; Growth Hormone; Immune Sera; Insulin; Insulin Secretion; Male; Naloxone; Naltrexone; Rats; Time Factors | 1979 |
Continuous intravenous naltrexone effects on morphine self-administration in rhesus monkeys.
Topics: Animals; Dose-Response Relationship, Drug; Haplorhini; Infusions, Parenteral; Macaca mulatta; Morphine; Naloxone; Naltrexone; Self Administration; Time Factors | 1978 |
Withdrawal from endogenous opiates.
Topics: Endorphins; Humans; Naloxone; Naltrexone; Schizophrenia; Substance Withdrawal Syndrome | 1979 |
Endogenous opioid peptides and the control of pain.
Topics: Analgesia; Animals; Cats; Central Nervous System; Endorphins; Humans; Naloxone; Naltrexone; Pain; Spinal Cord; Substance P; Swine | 1979 |
Naltrexone antagonism of exploration in the rat.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Endorphins; Exploratory Behavior; Male; Motor Activity; Naloxone; Naltrexone; Rats | 1979 |
Nitrous oxide stimulation of locomotor activity: evidence for an opiate-like behavioral effect.
Topics: Adaptation, Psychological; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotics; Nitrous Oxide | 1979 |
Evidence supporting lack of discriminative stimulus properties of a combination of naltrexone and morphine.
Topics: Animals; Discrimination, Psychological; Drug Interactions; Generalization, Stimulus; Gerbillinae; Male; Morphine; Naloxone; Naltrexone | 1979 |
Facilitation by opiate antagonists of sexual performance in the male rat.
Topics: Animals; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Time Factors | 1979 |
Comparison of binding of [3H]-methionine-enkephalin, [3H]-naltrexone and [3H]-dihydromorphine in the mouse vas deferens and the myenteric plexus and brain of the ginea pig.
Topics: Animals; Brain; Dihydromorphine; Endorphins; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Mice; Morphine Derivatives; Myenteric Plexus; Naloxone; Naltrexone; Organ Specificity; Stereoisomerism; Vas Deferens | 1979 |
Acute effects of opiate agonists, partial agonists and antagonists on brain monoamines in the rat.
Topics: Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Cyclazocine; Dextrorphan; Female; Levallorphan; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pentazocine; Rats | 1979 |
Studies of the possible role of brain endorphins in pentobarbital anesthesia and toxicity in mice.
Topics: Animals; Brain; Endorphins; Enkephalins; Leucine; Male; Mice; Morphine; Naloxone; Naltrexone; Pentobarbital; Phenylalanine | 1979 |
Enhanced analgesic effects of stress following chronic administration of naltrexone in rats.
Topics: Analgesia; Animals; Male; Naloxone; Naltrexone; Rats; Reaction Time; Stress, Physiological; Time Factors | 1979 |
Plasma and semen kinetics of naltrexone in the rabbit.
Topics: Animals; Half-Life; Kinetics; Male; Naloxone; Naltrexone; Rabbits; Semen | 1979 |
Increased amphetamine potency following chronic naltrexone administration in rats.
Topics: Animals; Apomorphine; Dextroamphetamine; Drug Synergism; Male; Motor Activity; Naloxone; Naltrexone; Rats; Time Factors | 1979 |
Inhibition of drug metabolism by chronically administered naltrexone.
Topics: Animals; Cytochrome P-450 Enzyme System; Depression, Chemical; Drug Implants; Liver; Male; Mice; Mixed Function Oxygenases; Naloxone; Naltrexone; Pharmaceutical Preparations; Time Factors | 1979 |
Suppressant effects of naltrexone on water intake in rats.
Topics: Animals; Body Weight; Depression, Chemical; Drinking Behavior; Female; Naloxone; Naltrexone; Pain; Quinine; Rats; Self Administration; Sensory Thresholds; Time Factors; Water Deprivation | 1979 |
Effects of contingent payment on compliance with a naltrexone regimen.
Topics: Adult; Behavior Therapy; Consumer Behavior; Heroin Dependence; Humans; Length of Stay; Male; Naloxone; Naltrexone; Patient Compliance; Reinforcement Schedule | 1979 |
Behavioral effects of perinatal naltrexone exposure: a preliminary investigation.
Topics: Analgesics; Animals; Animals, Newborn; Behavior, Animal; Conditioning, Operant; Electroshock; Emotions; Female; Morphine; Motor Activity; Naloxone; Naltrexone; Pregnancy; Rats; Reaction Time | 1979 |
Chronic naltrexone administration reverses the suppressive effect of crowding on body weight gain in rats.
Topics: Animals; Body Weight; Crowding; Male; Naloxone; Naltrexone; Rats; Time Factors | 1979 |
Differentiation between opioid peptides by naltrexone.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Naloxone; Naltrexone; Peptides; Vas Deferens | 1977 |
The pharmacology of thebaine in the chronic spinal dog.
Topics: Animals; Dogs; Humans; Naloxone; Naltrexone; Spinal Cord; Substance Withdrawal Syndrome; Substance-Related Disorders; Thebaine; Time Factors | 1978 |
The effects of naltrexone on the development of physical dependence on morphine.
Topics: Animals; Behavior, Animal; Body Temperature; Brain; Drug Implants; Humans; Male; Mice; Morphine; Morphine Dependence; Naloxone; Naltrexone; Time Factors | 1978 |
Discriminative stimulus effects of naltrexone in the morphine-dependent rat.
Topics: Animals; Generalization, Stimulus; Humans; Male; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Prejudice; Rats; Substance Withdrawal Syndrome; Time Factors | 1979 |
Prospects, problems, side effects, and safety of narcotic antagonists.
Topics: Cyclazocine; Delayed-Action Preparations; Humans; Naloxone; Naltrexone; Psychotherapy; Reinforcement, Social | 1977 |
Possible withdrawal from endogeneous opiates in schizophrenics.
Topics: Female; Humans; Male; Naloxone; Naltrexone; Schizophrenia; Substance Withdrawal Syndrome; Time Factors | 1978 |
Prlonged drug release from multiple emulsions.
Topics: Delayed-Action Preparations; Emulsions; Half-Life; Naloxone; Naltrexone; Technology, Pharmaceutical | 1978 |
Inhibition by d,l-methadone of RNA and protein synthesis in neonatal mice: antagonism by naloxone or naltrexone.
Topics: Animals; Animals, Newborn; Depression, Chemical; Liver; Methadone; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Protein Biosynthesis; RNA; Time Factors | 1978 |
Plasma corticosteroid levels in rats maintained on a long-acting naltrexone delivery system.
Topics: Adrenal Cortex Hormones; Animals; Drug Implants; Male; Morphine; Naloxone; Naltrexone; Rats; Reaction Time; Time Factors | 1978 |
Stereospecific aversive property of narcotic antagonists in morphine-free rats.
Topics: Animals; Avoidance Learning; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Stereoisomerism; Structure-Activity Relationship | 1978 |
The identification and measurement of two new metabolites of naltrexone in human urine.
Topics: Animals; Chromatography, Gas; Half-Life; Humans; Male; Mass Spectrometry; Naloxone; Naltrexone; Rats | 1978 |
Naltrexone, morphine and cocaine interactions in mice and rats.
Topics: Animals; Cocaine; Drug Interactions; Lethal Dose 50; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Reaction Time; Reflex | 1978 |
Effects of repeated injections of naltrexone on antagonism of rate decreases by morphine in the pigeon.
Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Male; Morphine; Naloxone; Naltrexone; Time Factors | 1978 |
Narcotic antagonist treatment: clinical experience with naltrexone.
Topics: Adolescent; Adult; Attitude; Drug Evaluation; Emotions; Employment; Follow-Up Studies; Heroin Dependence; Humans; Male; Middle Aged; Naloxone; Naltrexone; Patient Compliance; Psychiatric Status Rating Scales; Time Factors | 1978 |
Discriminative effects of morphine in the pigeon.
Topics: Animals; Columbidae; Dextrorphan; Discrimination, Psychological; Generalization, Psychological; Humans; Levorphanol; Morphine; Naloxone; Naltrexone; Time Factors | 1978 |
Carbon-13 nuclear magnetic resonance identification of 2-hydroxy-3-O-methyl-6beta-naltrexol as a minor naltrexone metabolite.
Topics: Adult; Humans; Magnetic Resonance Spectroscopy; Male; Naloxone; Naltrexone | 1978 |
Naltrexone and conventionality.
Topics: Adolescent; Adult; Crime; Drug Evaluation; Economics; Employment; Heroin Dependence; Humans; Life Style; Male; Marriage; Middle Aged; Naloxone; Naltrexone; Patient Compliance; Residence Characteristics; Social Conformity | 1978 |
Craving in heroin addicts maintained on the opiate antagonist naltrexone.
Topics: Heroin Dependence; Humans; Naloxone; Naltrexone; Patient Dropouts | 1978 |
Alteration of ethanol effects by opiate antagonists.
Topics: Animals; Body Temperature; Calcium; Drug Interactions; Ethanol; Fasting; Female; Lethal Dose 50; Male; Mice; Motor Activity; Naloxone; Naltrexone; Rats; Reflex; Sleep; Species Specificity | 1979 |
Pharmacokinetics of naloxone and naltrexone in the dog.
Topics: Animals; Dogs; Female; Half-Life; Kinetics; Male; Naloxone; Naltrexone; Radioimmunoassay | 1979 |
Development of polylactic/glycolic acid delivery systems for use in treatment of narcotic addiction.
Topics: Animals; Drug Implants; Foreign-Body Reaction; Lactates; Male; Mice; Morphine; Naloxone; Naltrexone; Polyglycolic Acid; Polymers; Reaction Time; Time Factors | 1976 |
Naltrexone bibliography.
Topics: Bibliographies as Topic; Naloxone; Naltrexone | 1976 |
Metabolic reduction of naltrexone. I. Synthesis, separation and characterization of naloxone and naltrexone reduction products and qualitative assay of urine and bile following administration of naltrexone, alpha-naltrexol, or beta-naltrexol.
Topics: Animals; Bile; Chromatography, Gas; Chromatography, Thin Layer; Circular Dichroism; Dogs; Guinea Pigs; Haplorhini; Humans; Magnetic Resonance Spectroscopy; Mice; Naloxone; Naltrexone; Optical Rotation; Oxidation-Reduction; Rats; Stereoisomerism | 1975 |
Tritiated naltrexone binding in plasma from several species and tissue distribution in mice.
Topics: Animals; Dogs; Female; Guinea Pigs; Haplorhini; Humans; Macaca mulatta; Male; Mice; Naloxone; Naltrexone; Rats; Species Specificity; Time Factors | 1976 |
Assessment of CNS drug activity in rhesus monkeys by analysis of the EEG.
Topics: Amobarbital; Animals; Brain; Clorazepate Dipotassium; Codeine; Computers; Electroencephalography; Glutethimide; Haplorhini; Macaca mulatta; Morphine; Nalbuphine; Naloxone; Naltrexone | 1976 |
[Precipitation and prevention of abstinence in acutely morphinized rats and mice: comparisons between naloxone, naltrexone, and diprenorphine (author's transl)].
Topics: Animals; Diprenorphine; Humans; Male; Mice; Morphinans; Morphine; Morphine Dependence; Naloxone; Naltrexone; Rats; Substance Withdrawal Syndrome; Time Factors | 1976 |
Metabolic reduction of naltrexone II. In vitro studies using liver from guinea pig, monkey and rat.
Topics: Animals; Guinea Pigs; Haplorhini; In Vitro Techniques; Isomerism; Liver; Macaca mulatta; Male; Naloxone; Naltrexone; Oxidation-Reduction; Rats; Species Specificity; Subcellular Fractions | 1976 |
Blockade of the discriminative effects of morphine in the rat by naltrexone and naloxone.
Topics: Administration, Oral; Animals; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Morphine; Naloxone; Naltrexone; Rats; Time Factors | 1976 |
Testing of drug delivery systems for use in the treatment of narcotic addiction.
Topics: Animals; Blood Proteins; Dogs; Drug Implants; Guinea Pigs; Haplorhini; Humans; Kinetics; Mice; Morphine; Naloxone; Naltrexone; Protein Binding; Rats; Reaction Time; Species Specificity; Substance-Related Disorders | 1975 |
Evaluation of narcotic and narcotic antagonist interactions in primates.
Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration | 1976 |
The effect of the narcotic antagonists naloxone, naltrexone and nalorphine on spinal cord C-fiber reflexes evoked by electrical stimulation or radiant heat.
Topics: Action Potentials; Animals; Cats; Decerebrate State; Electric Stimulation; Hot Temperature; Nalorphine; Naloxone; Naltrexone; Reflex; Spinal Cord; Time Factors | 1977 |
Naloxone-precipitated withdrawal: a method for rapid induction onto naltrexone.
Topics: Adult; Drug Administration Schedule; Drug Therapy, Combination; Heroin Dependence; Humans; Male; Methadone; Methods; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders | 1977 |
Antagonism of the effects of pentobarbital in the chronic spinal dog by naltrexone.
Topics: Animals; Body Temperature; Consciousness; Dogs; Heart Rate; Naloxone; Naltrexone; Pentobarbital; Reflex; Spinal Cord | 1977 |
Naltrexone treatment of opiate-dependent persons.
Topics: Adult; Humans; Male; Methadone; Middle Aged; Naloxone; Naltrexone; Narcotics; Substance-Related Disorders | 1977 |
Quantitative determination of naltrexone and naltrexone prodrugs by electron-capture gas-liquid chromatography.
Topics: Chromatography, Gas; Esters; Ethers; Hydrolysis; Naloxone; Naltrexone; Solutions | 1977 |
Stereochemical studies on medicinal agents. 23. Synthesis and biological evaluation of 6-amino derivatives of naloxone and naltrexone.
Topics: Amination; Analgesics; Animals; Binding, Competitive; In Vitro Techniques; Male; Mice; Morphine; Naloxone; Naltrexone; Stereoisomerism | 1977 |
Estimation of the systemic availability and other pharmacokinetic parameters of naltrexone in man after acute and chronic oral administration.
Topics: Administration, Oral; Biological Availability; Half-Life; Humans; Kinetics; Naloxone; Naltrexone; Time Factors | 1977 |
An oral opiate antagonist in chronic schizophrenia: a pilot study.
Topics: Administration, Oral; Adult; Drug Evaluation; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Pilot Projects; Schizophrenia | 1977 |
Effects of acute and chronic morphine and narcotic antagonists on brain energy metabolism.
Topics: Animals; Brain; Citrates; Energy Metabolism; Glucose; Malates; Male; Mice; Morphine; Naloxone; Naltrexone; Pyruvates | 1977 |
Comparison of withdrawal precipitating properties of various morphine antagonists and partial agonists in relation to their stereospecific binding to brain homogenates.
Topics: Benzomorphans; Binding Sites; Brain; Humans; Levallorphan; Morphine Dependence; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Pentazocine; Receptors, Drug; Sodium; Stereoisomerism; Subcellular Fractions; Substance Withdrawal Syndrome | 1976 |
A behavioral paradigm for the evaluation of narcotic antagonists.
Topics: Adult; Cyclazocine; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Research Design | 1976 |
Reinstatement of precipitated narcotic withdrawal hypothermia in the rat.
Topics: Animals; Body Temperature; Female; Humans; Morphine; Naloxone; Naltrexone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1976 |
Naltrexone: disposition, metabolism, and effects after acute and chronic dosing.
Topics: Adult; Drug Administration Schedule; Half-Life; Heroin; Humans; Kinetics; Male; Naloxone; Naltrexone; Pupil; Respiration; Time Factors | 1976 |
The structure-action relationship and kinetics of some naloxone and naltrexone derivatives.
Topics: Animals; Cyclazocine; Guinea Pigs; Ileum; Kinetics; Morphine; Morphine Derivatives; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Structure-Activity Relationship; Time Factors | 1976 |
Sustained release of naltrexone from glyceride implants.
Topics: Animals; Delayed-Action Preparations; Drug Implants; Glycerides; Male; Mice; Morphine; Naloxone; Naltrexone; Reaction Time; Time Factors | 1976 |
Morphine-naloxone interaction in the central cholinergic system: the influence of subcortical lesioning and electrical stimulation.
Topics: Acetylcholine; Animals; Brain; Cerebral Cortex; Drug Interactions; Electric Stimulation; In Vitro Techniques; Morphine; Naloxone; Naltrexone; Parasympathetic Nervous System; Rats; Time Factors | 1976 |
Determination of naloxone and naltrexone as perfluoroalkyl ester derivatives by electron-capture gas-liquid chromatography.
Topics: Anhydrides; Chromatography, Gas; Chromatography, Liquid; Mass Spectrometry; Naloxone; Naltrexone | 1976 |
Ring C conformation of 6beta-naltrexol and 6alpha-naltrexol. Evidence from proton and carbon-13 nuclear magnetic resonance.
Topics: Magnetic Resonance Spectroscopy; Molecular Conformation; Naloxone; Naltrexone | 1976 |
Nitrous oxide "analgesia": resemblance to opiate action.
Topics: Analgesia; Animals; Drug Tolerance; Mice; Morphine; Naloxone; Naltrexone; Nitrous Oxide | 1976 |
Ethanol preference in the hamster: effects of morphine sulfate and naltrexone, a long-acting morphine antagonist.
Topics: Alcohol Drinking; Animals; Choice Behavior; Cricetinae; Decision Making; Dextrorphan; Levorphanol; Morphine; Naloxone; Naltrexone; Time Factors | 1976 |
Psychopathology and mood during heroin use: acute vs chronic effects.
Topics: Acute Disease; Adult; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emotions; Euphoria; Heroin; Heroin Dependence; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Naltrexone; Psychopathology | 1976 |
Short-term effects of naltrexone in 155 heroin ex-addicts.
Topics: Abdomen; Administration, Oral; Blood Pressure; Brain; Dose-Response Relationship, Drug; Drug Evaluation; Heart; Heroin Dependence; Humans; Naloxone; Naltrexone; Pain; Respiration; Substance-Related Disorders; Time Factors | 1976 |
An analysis of naltrexone use--its efficacy, safety and potential.
Topics: Adult; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Methadone; Middle Aged; MMPI; Naloxone; Naltrexone; Outpatient Clinics, Hospital; Patient Compliance; Patient Dropouts; Personality Inventory; Substance-Related Disorders | 1976 |
Interactions of narcotics, narcotic antagonists, and ethanol during acute, chronic, and withdrawal states.
Topics: Alcohol Drinking; Animals; Animals, Newborn; Dextrorphan; Drug Interactions; Ethanol; Humans; Levorphanol; Male; Methadone; Methadyl Acetate; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1976 |
Clinical efficacy of naltrexone: a one year follow up.
Topics: Adult; Follow-Up Studies; Heroin Dependence; Humans; Naloxone; Naltrexone; Time Factors | 1976 |
Treatment of heroin dependence with naltrexone.
Topics: Heroin Dependence; Humans; Naloxone; Naltrexone | 1975 |
Isolation and identification of a new metabolite of naltrexone in human blood and urine.
Topics: Adult; Biological Availability; Chromatography, Gas; Chromatography, Thin Layer; Erythrocytes; Humans; Hydroxylation; Mass Spectrometry; Naloxone; Naltrexone; Time Factors | 1975 |
Comparative in vivo distribution of opiate agonists and antagonists by means of double isotope techniques.
Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Dose-Response Relationship, Drug; Liver; Male; Morphine; Naloxone; Naltrexone; Rats; Time Factors; Tritium | 1975 |
Acetylcholine storage and its stabilization by morphine.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Morphine; Naloxone; Naltrexone; Sodium Chloride; Spectrometry, Fluorescence; Synaptosomes | 1975 |
Influence of catecholaminergic agents on narcotic binding in brain.
Topics: Animals; Brain; Catecholamines; Dopamine; In Vitro Techniques; Kinetics; Male; Naloxone; Naltrexone; Norepinephrine; Rats | 1975 |
On the role of chemotherapy in the treatment of heroin addiction.
Topics: Heroin Dependence; Humans; Methadone; Methadyl Acetate; Motivation; Naloxone; Naltrexone; Substance-Related Disorders | 1975 |
Naltrexone pharmacology, pharmacokinetics, and metabolism: current status.
Topics: Administration, Oral; Animals; Biological Availability; Biotransformation; Chickens; Delayed-Action Preparations; Dogs; Drug Evaluation, Preclinical; Guinea Pigs; Half-Life; Heroin Dependence; Humans; Injections, Intravenous; Injections, Subcutaneous; Kinetics; Mice; Naloxone; Naltrexone; Rats; Species Specificity; Time Factors | 1975 |
Clinical experience with naltrexone.
Topics: Administration, Oral; Adult; Female; Heroin Dependence; Hospitalization; Humans; Male; Methadone; Middle Aged; Morphine; Naloxone; Naltrexone; Outpatient Clinics, Hospital; Patient Dropouts; Placebos; Time Factors | 1975 |
The clinical usefulness of narcotic antagonists: preliminary findings on the use of naltrexone.
Topics: Adult; Alcoholism; Boston; Cannabis; Depression; Emotions; Follow-Up Studies; Heroin Dependence; Humans; Internal-External Control; Male; Naloxone; Naltrexone; Patient Acceptance of Health Care; Patient Dropouts; Psychotherapy; Self Concept; Sleep | 1975 |
Clinical use of naltrexone (EN 1639 A). Part II: experience with the first 50 patients in a New York City treatment clinic.
Topics: Administration, Oral; Ambulatory Care; Educational Status; Employment; Ethnicity; Female; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; New York City; Patient Dropouts | 1975 |
Patient deaths in a narcotic antagonist (naltrexone) and l-alpha-acetylmethadol program.
Topics: Adult; Heroin Dependence; Homicide; Humans; Male; Methadone; Methadyl Acetate; Naloxone; Naltrexone; Psychotropic Drugs; Substance-Related Disorders; Suicide | 1975 |
Naltrexone study guidelines: good vehicle--wrong destination.
Topics: Drug Evaluation; Heroin Dependence; Humans; Motivation; Naloxone; Naltrexone; Research Design | 1975 |
Sustained release of naltrexone from glyceride implants.
Topics: Animals; Biodegradation, Environmental; Chemistry, Pharmaceutical; Drug Implants; Glycerides; Histocompatibility; Mice; Morphine; Naloxone; Naltrexone; Reaction Time; Time Factors | 1975 |
Use of synthetic polypeptides in the preparation of biodegradable delivery vehicles for narcotic antagonists.
Topics: Animals; Biodegradation, Environmental; Drug Implants; Glutamates; Leucine; Mice; Morphine; Naloxone; Naltrexone; Peptides; Reaction Time; Time Factors | 1975 |
Lactic/glycolic acid polymers as narcotic antagonist delivery systems.
Topics: Animals; Behavior, Animal; Drug Implants; Glycolates; Humans; In Vitro Techniques; Lactates; Male; Mice; Naloxone; Naltrexone; Polymers; Structure-Activity Relationship; Substance-Related Disorders | 1975 |
Development of polylactic/glycolic acid delivery systems for use in treatment of narcotic addiction.
Topics: Animals; Biodegradation, Environmental; Drug Implants; Humans; Lactates; Male; Mice; Naloxone; Naltrexone; Polyglycolic Acid; Polymers; Substance-Related Disorders; Time Factors | 1975 |
Development of injectable microcapsules for use in the treatment of narcotic addiction.
Topics: Animals; Capsules; Delayed-Action Preparations; Humans; Injections; Lactates; Mice; Microspheres; Naloxone; Naltrexone; Polyglycolic Acid; Polymers; Substance-Related Disorders | 1975 |
Quantitative determination of naltrexone and beta-naltrexol in human plasma using electron detection.
Topics: Chromatography, Gas; Dose-Response Relationship, Drug; Humans; Naloxone; Naltrexone | 1976 |
Use of narcotic (opiate) antagonists.
Topics: Cyclazocine; Humans; Naloxone; Naltrexone; Narcotic Antagonists | 1976 |
An evaluation of the hot plate technique to study narcotic antagonists.
Topics: Animals; Male; Methods; Mice; Models, Biological; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Reaction Time; Time Factors | 1976 |
Involvement of opioid mechanisms in peripheral motor control of detrusor muscle.
Topics: Animals; Electric Stimulation; Enkephalins; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Humans; Indoles; Male; Morphinans; Morphine; Muscle Contraction; Muscles; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance P; Sympatholytics | 1992 |
Kappa-/mu-receptor interactions in the opioid control of the in vivo release of substance P-like material from the rat spinal cord.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kinetics; Male; Models, Neurological; Naloxone; Naltrexone; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance P | 1992 |
Perinatal morphine exposure alters peptidergic development in the striatum.
Topics: Animals; Blotting, Northern; Body Weight; Corpus Striatum; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Growth; Immunohistochemistry; In Situ Hybridization; Morphine; Naloxone; Naltrexone; Protein Precursors; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Substance P | 1992 |
Comparison of the neurochemistry of the endogenous opioid systems in two brainstem pain-processing centers.
Topics: Animals; Brain Stem; Dipeptides; Dose-Response Relationship, Drug; Medulla Oblongata; Microinjections; Naloxone; Naltrexone; Neprilysin; Pain; Periaqueductal Gray; Rats | 1992 |
Erythrocytes as carriers of new anti-opioid prodrugs: in vitro studies.
Topics: Drug Carriers; Drug Stability; Erythrocyte Membrane; Hemolysis; Humans; In Vitro Techniques; Molecular Structure; Naloxone; Naltrexone; Plasma; Prodrugs | 1992 |
Effects of naloxone and nalmefene in rat spinal cord injury induced by the ventral compression technique.
Topics: Animals; Drug Evaluation, Preclinical; Intervertebral Disc Displacement; Naloxone; Naltrexone; Nerve Crush; Paralysis; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord Injuries; Spinal Fractures | 1992 |
A highly selective kappa-opioid receptor agonist, CI-977, reduces excitatory synaptic potentials in the rat locus coeruleus in vitro.
Topics: Amino Acids; Analgesics; Animals; Benzofurans; Benzomorphans; Bicuculline; Depression, Chemical; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Ligands; Locus Coeruleus; Membrane Potentials; Naloxone; Naltrexone; Picrotoxin; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1992 |
Kappa-opioid receptor stimulation abolishes mu- but not delta-mediated inhibitory control of spinal Met-enkephalin release.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Indoles; Injections, Spinal; Male; Morphinans; Naloxone; Naltrexone; Neurons; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1992 |
Kappa opioid mediation of fetal responses to milk.
Topics: Aging; Animals; Arousal; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Fetal Movement; Gestational Age; Morphine; Motor Activity; Naloxone; Naltrexone; Pregnancy; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Sucking Behavior; Taste; Touch | 1992 |
Hypothermic effect of D-Ala-deltorphin II, a selective delta opioid receptor agonist.
Topics: Animals; Body Temperature; Indoles; Injections, Intraventricular; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1992 |
Naloxone-induced analgesia in diabetic mice.
Topics: Analgesia; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Indoles; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1992 |
Interaction between opioid antagonists and amphetamine: evidence for mediation by central delta opioid receptors.
Topics: Amphetamine; Analgesia; Animals; Brain; Indoles; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1992 |
Effects of diabetes on stress-induced analgesia in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Physical Exertion; Receptors, Opioid, mu; Sensory Thresholds; Stress, Physiological | 1992 |
Spinal antinociception by Tyr-D-Ser(otbu)-Gly-Phe-Leu-Thr, a selective delta-opioid receptor agonist.
Topics: Amino Acid Sequence; Analgesics; Animals; Dose-Response Relationship, Drug; Indoles; Injections, Spinal; Male; Molecular Sequence Data; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1992 |
Evidence that endogenous opioids mediate the antinociceptive effects of intrathecally administered calcium in mice.
Topics: Analgesia; Animals; Calcium; Drug Interactions; Endorphins; Indoles; Injections, Spinal; Male; Mice; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1992 |
Antagonist-induced transient down-regulation of delta-opioid receptors in NG108-15 cells.
Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Concanavalin A; Down-Regulation; Enkephalin, Leucine-2-Alanine; Glioma; Kinetics; Lysosomes; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Subcellular Fractions; Tritium; Tumor Cells, Cultured | 1992 |
Effects of the delta-opioid receptor antagonist naltrindole on antinociceptive responses to selective delta-agonists in post-weanling rats.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, delta | 1992 |
Diprenorphine as a stimulus in drug discrimination learning.
Topics: Animals; Chlorides; Conditioning, Psychological; Diprenorphine; Discrimination Learning; Dose-Response Relationship, Drug; Female; Generalization, Psychological; Lithium; Lithium Chloride; Morphine; Nalorphine; Naloxone; Naltrexone; Pentobarbital; Rats | 1992 |
The pruritus of cholestasis and the opioid system.
Topics: Cholangitis, Sclerosing; Female; Humans; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Pruritus; Receptors, Opioid | 1992 |
Opioid receptor antagonist affinity ligands: 6 beta-bromoacetamido-6-desoxynaltrexone and 6 beta-thioglycolamido-6-desoxynaltrexone.
Topics: Affinity Labels; Analgesia; Animals; Brain; Cattle; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Quinuclidinyl Benzilate; Receptors, Opioid | 1992 |
The stimulation of central kappa opioid receptors decreases male sexual behavior and locomotor activity.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Body Temperature; Injections; Male; Motor Activity; Naloxone; Naltrexone; Nucleus Accumbens; Preoptic Area; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Sexual Behavior, Animal; Tegmentum Mesencephali | 1992 |
On the mechanism of the interaction of ketamine and halothane in vitro.
Topics: Animals; Drug Interactions; GTP-Binding Proteins; Guinea Pigs; Halothane; Ileum; In Vitro Techniques; Ketamine; Muscle, Smooth; Muscle, Smooth, Vascular; Myenteric Plexus; Naloxone; Naltrexone; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella | 1992 |
Kappa-opioids decrease excitatory transmission in the dentate gyrus of the guinea pig hippocampus.
Topics: Action Potentials; Animals; Benzeneacetamides; Diprenorphine; Dynorphins; Electrophysiology; Endorphins; Guinea Pigs; Hippocampus; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1992 |
Naloxone and norbinaltorphimine administered intracerebroventricularly antagonize spinal morphine-induced antinociception in mice through the antianalgesic action of spinal dynorphin A (1-17).
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone | 1992 |
Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Animals; Benzofurans; Bicuculline; Bombesin; Cholecystokinin; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Naloxone; Naltrexone; Neurons; Picrotoxin; Prazosin; Pyrrolidines; Quinoxalines; Raphe Nuclei; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Synapses; Tetrodotoxin | 1992 |
Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Hemoglobins; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Morphine; MSH Release-Inhibiting Hormone; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1992 |
Endogenous opioids may be involved in idazoxan-induced food intake.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Eating; Endorphins; Idazoxan; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains | 1992 |
Effects of the opiates on the paraventricular nucleus in genetically polydipsic mice.
Topics: Animals; Dynorphins; Female; In Vitro Techniques; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Microinjections; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Paraventricular Hypothalamic Nucleus; Quaternary Ammonium Compounds; Synapses; Thirst | 1992 |
Identification of a novel receptor mediating substance P-induced behavior in the mouse.
Topics: Analysis of Variance; Animals; Behavior, Animal; Binding Sites; Indoles; Injections, Spinal; Male; Mice; Morphinans; Naloxone; Naltrexone; Peptide Fragments; Substance P | 1992 |
Opioid modulation of thermal dehydration-induced thirst in rats.
Topics: Animals; Dehydration; Dose-Response Relationship, Drug; Hot Temperature; Injections, Intraperitoneal; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Thirst | 1992 |
Repeated systemic administration of the mixed inhibitor of enkephalin-degrading enzymes, RB101, does not induce either antinociceptive tolerance or cross-tolerance with morphine.
Topics: Analgesics; Animals; Disulfides; Dose-Response Relationship, Drug; Drug Tolerance; Indoles; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Phenylalanine; Prodrugs; Reaction Time | 1992 |
Analgesic and aversive effects of naloxone in BALB/c mice.
Topics: Analgesia; Animals; Choice Behavior; Dose-Response Relationship, Drug; Formaldehyde; Mice; Mice, Inbred BALB C; Naloxone; Naltrexone; Pain | 1992 |
Effects of beta-funaltrexamine on butorphanol dependence.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Butorphanol; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Reinforcement Schedule; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
Naloxone as a stimulus in drug discrimination learning: generalization to other opiate antagonists.
Topics: Animals; Cues; Diprenorphine; Discrimination Learning; Female; Generalization, Psychological; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saccharin | 1992 |
Apparent pA2 value of naltrexone is not changed in rats following continuous exposure to morphine or naloxone.
Topics: Analysis of Variance; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Fentanyl; Male; Morphine; Naloxone; Naltrexone; Pain Measurement; Rats; Rats, Inbred Strains | 1992 |
Feedback inhibition of met-enkephalin release from the rat spinal cord in vivo.
Topics: Animals; Calcitonin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Feedback; Indoles; Injections, Spinal; Leucine; Male; Morphinans; Naloxone; Naltrexone; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan | 1992 |
(D-Ala2)deltorphin II: D1-dependent stereotypies and stimulation of dopamine release in the nucleus accumbens.
Topics: Animals; Brain; Caudate Nucleus; Cerebral Ventricles; Dopamine; Endorphins; Functional Laterality; Indoles; Infusions, Parenteral; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereotyped Behavior | 1991 |
Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; gamma-Aminobutyric Acid; Indoles; Male; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Phenytoin; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1991 |
Opioid delta agonists and endogenous enkephalins induce different emotional reactivity than mu agonists after injection in the rat ventral tegmental area.
Topics: Animals; Anxiety; Emotions; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Exploratory Behavior; Indoles; Injections; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tegmentum Mesencephali | 1991 |
Endogenous opioids tonically inhibit the depressor neurones in the caudal ventrolateral medulla of rabbits: mediation through delta- and kappa-receptors.
Topics: Amino Acid Sequence; Animals; Endorphins; Enkephalin, Leucine; Hemodynamics; Male; Medulla Oblongata; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1991 |
Endogenous opioids regulate cell proliferation in the retina of developing rat.
Topics: Animals; Animals, Newborn; Autoradiography; Cell Division; DNA Replication; Endorphins; Enkephalin, Methionine; Female; Iodine Radioisotopes; Male; Mitotic Index; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Retina; Retinal Ganglion Cells; Thymidine | 1991 |
Effects of parabrachial opioid antagonism on stimulation-induced feeding.
Topics: Animals; Electric Stimulation; Feeding Behavior; Hypothalamus; Infusions, Parenteral; Male; Microinjections; Naloxone; Naltrexone; Pons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values | 1991 |
The opioid activity and receptor selectivity of fluorinated Leu5 enkephalin analogues in vitro and in vivo.
Topics: Analgesics; Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred Strains; Morphinans; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1991 |
Evaluation of receptor mechanism mediating fentanyl analgesia and toxicity.
Topics: Analgesics; Animals; Brain; Drug Tolerance; Fentanyl; Lethal Dose 50; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1991 |
Opiate receptor antagonists for delusions of parasitosis.
Topics: Delusions; Female; Fentanyl; Fluspirilene; Humans; Middle Aged; Myiasis; Naloxone; Naltrexone; Narcotic Antagonists | 1991 |
Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues.
Topics: Alkylation; Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; Kinetics; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil; Vas Deferens | 1991 |
In vitro effect of high doses of morphine on Con A induced lymphokine production.
Topics: Animals; beta-Endorphin; Cell Survival; Cells, Cultured; Clone Cells; Colforsin; Concanavalin A; Cyclic AMP; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Enkephalins; Female; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Protein Biosynthesis; Receptors, Opioid; Spleen; T-Lymphocytes, Helper-Inducer | 1991 |
An enkephalinergic mechanism involved in amygdaloid suppression of affective defence behavior elicited from the midbrain periaqueductal gray in the cat.
Topics: Affect; Aggression; Amygdala; Animals; Cats; Electric Stimulation; Enkephalin, Leucine; Enkephalins; Female; Fluorescent Dyes; Homocysteine; Immunohistochemistry; Male; Naloxone; Naltrexone; Narcotic Antagonists; Periaqueductal Gray; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereotyped Behavior; Stilbamidines | 1991 |
Behavioural effects of deltorphins in rats.
Topics: Analgesics; Animals; Behavior, Animal; Indoles; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Social Behavior; Stereotyped Behavior | 1991 |
Inhibition of suckling-induced prolactin release by mu- and kappa-opioid antagonists.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Lactation; Luteinizing Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1991 |
Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1991 |
Hippocampal mu-receptors mediate opioid reinforcement in the CA3 region.
Topics: Animals; Dynorphins; Enkephalin, Leucine; Hippocampus; Kinetics; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Reference Values; Reinforcement, Psychology; Self Administration | 1991 |
U-50,488H inhibits dynorphin and glutamate release from guinea pig hippocampal mossy fiber terminals.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcium; Dynorphins; Enkephalin, Leucine; Glutamates; Guinea Pigs; Hippocampus; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Endings; Potassium Chloride; Pyrrolidines; Synaptosomes | 1991 |
Intrathecal administration of dynorphin A and its fragments increase heart rate and arterial pressure in the urethane anesthetized rat: mediation by a nonopioid mechanism.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Anesthesia, General; Animals; Antihypertensive Agents; Blood Pressure; Diastole; Dynorphins; Heart Rate; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Injections, Spinal; Male; Naloxone; Naltrexone; Peptide Fragments; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Reference Values; Systole | 1991 |
Effect of opioid receptor antagonists on vasodilator nerve actions in the perfused rat mesentery.
Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanethidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Vasodilation | 1991 |
In vivo tonic inhibition of spinal substance P (-like material) release by endogenous opioid(s) acting at delta receptors.
Topics: Amino Acid Sequence; Animals; Depression, Chemical; Indoles; Injections, Spinal; Male; Molecular Sequence Data; Morphinans; Naloxone; Naltrexone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Secretory Rate; Spinal Cord; Substance P | 1991 |
Effects of naloxone and naltrexone on receptive and proceptive behaviors in female rats.
Topics: Animals; Female; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Stimulation, Chemical | 1992 |
Antagonism of acute cocaine toxicity by buprenorphine.
Topics: Analysis of Variance; Animals; Buprenorphine; Cocaine; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Male; Mice; Naloxone; Naltrexone | 1991 |
Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration.
Topics: Analgesics; Animals; Binding, Competitive; Drug Stability; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Naltrexone; Neprilysin; Tissue Distribution; Tritium | 1991 |
Research note: naloxone inhibits drinking in the chick induced by angiotensin II.
Topics: Angiotensin II; Animals; Chickens; Dose-Response Relationship, Drug; Drinking; Injections, Intramuscular; Injections, Subcutaneous; Male; Naloxone; Naltrexone | 1991 |
Antinociceptive and gastrointestinal transit effects of cholecystokinin (CCK-8) and related analogs of CCK-8 in the mouse.
Topics: Amino Acid Sequence; Analgesics; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Gastric Emptying; Gastrointestinal Transit; Indoles; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Peptides; Phenylurea Compounds; Reaction Time; Receptors, Cholecystokinin; Sincalide | 1991 |
Opiate antagonists inhibit feeding induced by 8-OH-DPAT: possible mediation in the nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Eating; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Quaternary Ammonium Compounds; Raphe Nuclei; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1991 |
Chronic selective blockade of mu opioid receptors produces analgesia and augmentation of the effects of a kappa agonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrrolidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereotaxic Techniques | 1991 |
Comparison of naloxonazine and beta-funaltrexamine antagonism of mu 1 and mu 2 opioid actions.
Topics: Animals; Drug Administration Schedule; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Subcutaneous; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
[Naloxone and naltrexone in the therapy of advanced COPD].
Topics: Humans; Lung Diseases, Obstructive; Male; Middle Aged; Naloxone; Naltrexone; Pulmonary Emphysema; Tomography, X-Ray Computed | 1991 |
Periaqueductal gray stimulation produces a spinally mediated, opioid antinociception for the inflamed hindpaw of the rat.
Topics: Analysis of Variance; Animals; Electric Stimulation; Freund's Adjuvant; Hindlimb; Inflammation; Male; Mycobacterium; Naloxone; Naltrexone; Pain; Periaqueductal Gray; Rats; Rats, Inbred Strains; Spinal Cord | 1991 |
Endothelin-1-induced nociception.
Topics: Animals; Endothelins; Male; Mice; Morphine; Naloxone; Naltrexone; Pain; Pain Measurement | 1991 |
Opiate antagonists reduce cocaine but not nicotine self-administration.
Topics: Animals; Cocaine; Conditioning, Operant; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Reinforcement Schedule; Self Administration | 1991 |
Electroacupuncture in rats: evidence for naloxone and naltrexone potentiation of analgesia.
Topics: Aging; Analgesia; Analysis of Variance; Animals; China; Electroacupuncture; Female; Male; Naloxone; Naltrexone; Pain; Pain Management; Rats; Rats, Inbred Strains; Sensory Thresholds; Sex Characteristics; Species Specificity; United States | 1991 |
Electroacupuncture analgesia in rats: naltrexone antagonism is dependent on previous exposure.
Topics: Analgesia; Analysis of Variance; Animals; China; Electroacupuncture; Male; Naloxone; Naltrexone; Pain; Pain Management; Rats; Rats, Inbred Strains; Species Specificity; Time Factors; United States | 1991 |
Effect of morphine administration on rat liver metallothionein and zinc metabolism.
Topics: Animals; Immobilization; Injections, Subcutaneous; Liver; Male; Metallothionein; Mifepristone; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Zinc | 1991 |
Role of opioid antagonists in the rat liver ischemia model.
Topics: Animals; Calcium Channel Blockers; Hepatic Artery; Ischemia; Liver; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Portal Vein; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Protective effect of nalmefene and naloxone on the ischemically damaged small bowel.
Topics: Animals; Intestine, Small; Ischemia; Mesenteric Arteries; Naloxone; Naltrexone; Narcotic Antagonists; Necrosis; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Opioids and feeding reward.
Topics: Animals; Appetite Regulation; Endorphins; Feeding Behavior; Naloxone; Naltrexone; Rats; Reward | 1991 |
The opioid receptor selectivity for trimebutine in isolated tissues experiments and receptor binding studies.
Topics: Animals; Drug Tolerance; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Rabbits; Receptors, Opioid; Trimebutine; Vas Deferens | 1990 |
Electric muscle stimulation in the spontaneously hypertensive rat induces a post-stimulatory reduction in activity: role of different opioid receptors.
Topics: Animals; Benzomorphans; Electric Stimulation; Hypertension; Male; Motor Activity; Muscles; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Receptors, Opioid | 1990 |
Kappa opiate receptors inhibit release of oxytocin from the magnocellular system during dehydration.
Topics: Animals; Benzomorphans; Dehydration; Dynorphins; Endorphins; Hypertonic Solutions; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Osmolar Concentration; Oxytocin; Peptide Fragments; Pituitary Gland, Posterior; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Vasopressins | 1990 |
Reflex peristalsis in the guinea pig isolated ileum is endogenously controlled by kappa opioid receptors.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peristalsis; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Somatostatin | 1990 |
Negative chronotropic but no antiarrhythmic effect of (+)- and (-)-naloxone in rats and guinea pigs.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Depression, Chemical; Guinea Pigs; Heart Rate; Male; Naloxone; Naltrexone; Ouabain; Rats; Stereoisomerism | 1991 |
Technique for greatly shortening the transition from methadone to naltrexone maintenance of patients addicted to opiates.
Topics: Adult; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methadone; Midazolam; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1991 |
Using antagonists to assess neurochemical coding of a drug's ability to establish a conditioned place preference.
Topics: Analgesics; Animals; Brain Chemistry; Conditioning, Operant; Flumazenil; Habituation, Psychophysiologic; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Scopolamine | 1990 |
5-Methylated naloxone, naltrexone, oxymorphone, and their 14-O-methyl ethers.
Topics: Animals; Ethers; In Vitro Techniques; Methylation; Naloxone; Naltrexone; Narcotic Antagonists; Oxymorphone; Quaternary Ammonium Compounds; Receptors, Opioid; Structure-Activity Relationship | 1990 |
Physical dependence on morphine using the mu receptor deficient CXBK mouse.
Topics: Animals; Mice; Mice, Inbred C57BL; Morphine Dependence; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, mu; Species Specificity; Substance Withdrawal Syndrome | 1990 |
Effects of chronic treatment with specific antagonists on analgesia and physical dependence on morphine in rats.
Topics: Analgesics; Animals; Indoles; Male; Morphinans; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Weight Loss | 1990 |
Selective opioid receptor antagonist effects upon intake of a high-fat diet in rats.
Topics: Animals; Dietary Fats; Dose-Response Relationship, Drug; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid | 1990 |
Apparent affinity of opioid antagonists in morphine-treated rhesus monkeys discriminating between saline and naltrexone.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Female; Indoles; Macaca mulatta; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu | 1990 |
Peripheral opioid receptors mediating antinociception in inflammation. Activation by endogenous opioids and role of the pituitary-adrenal axis.
Topics: Adrenalectomy; Analysis of Variance; Animals; Cold Temperature; Dose-Response Relationship, Drug; Endorphins; Foot; Hypophysectomy; Inflammation; Male; Naloxone; Naltrexone; Nociceptors; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming | 1990 |
Opioid receptor-mediated inhibition of dopamine and acetylcholine release from slices of rat nucleus accumbens, olfactory tubercle and frontal cortex.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Animals; Benzomorphans; Cerebral Cortex; Corpus Striatum; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ergolines; In Vitro Techniques; Male; Naloxone; Naltrexone; Nucleus Accumbens; Olfactory Bulb; Oxymetazoline; Pyrrolidines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Opioid; Septal Nuclei | 1990 |
Involvement of spinal kappa opioid receptors in the antinociception produced by intrathecally administered corticotropin-releasing factor in mice.
Topics: Animals; Corticotropin-Releasing Hormone; Drug Interactions; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Receptors, Opioid; Receptors, Opioid, kappa | 1990 |
Stereoselectivity and subtype of the opiate receptor involved in stress-induced hypertension.
Topics: Animals; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hypertension; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Social Isolation; Stereoisomerism; Stress, Psychological | 1990 |
"Paradoxical" analgesia and aggravated morphine dependence induced by opioid antagonists.
Topics: Animals; Body Weight; Indoles; Male; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1990 |
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress.
Topics: Analgesia; Animals; Dioxolanes; Dipeptides; Enkephalins; Inflammation; Leucine; Male; Naloxone; Naltrexone; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological; Swimming; Thiorphan | 1990 |
Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell cocultures.
Topics: Cells, Cultured; Gene Products, gag; HIV Core Protein p24; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Viral Core Proteins | 1990 |
Hepatobiliary effects of morphine are mediated in the brain.
Topics: Animals; Biliary Tract; Brain; Female; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Liver; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Sulfobromophthalein | 1990 |
Role of opioid receptors in the long-lasting blood pressure depression after electric muscle stimulation in the hind leg of the rat.
Topics: Animals; Benzomorphans; Blood Pressure; Electric Stimulation; Enkephalin, Leucine; Heart Rate; Hindlimb; Male; Naloxone; Naltrexone; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Receptors, Opioid; Regional Blood Flow | 1990 |
Simultaneous development of opioid tolerance and opioid antagonist-induced receptor upregulation.
Topics: Analgesia; Animals; Brain; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Male; Mice; Morphine; Naloxone; Naltrexone; Pain; Receptors, Opioid; Reference Values; Up-Regulation | 1990 |
[D-Pen2, D-Pen5]enkephalin, the standard delta opioid agonist, induces morphine-like behaviors in mice.
Topics: Analgesics; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Muscle Tonus; Naloxone; Naltrexone; Narcotic Antagonists; Stereotyped Behavior | 1990 |
Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases.
Topics: Adrenal Glands; Analgesics; Animals; Arginine Vasopressin; Blood Pressure; Corticosterone; Dexamethasone; Endocrine Glands; Heart Rate; Male; Monitoring, Physiologic; Naloxone; Naltrexone; Neural Pathways; Phenylephrine; Rats; Rats, Inbred Strains; Spinal Cord; Vasopressins | 1990 |
Antitussive effects of two specific kappa-opioid agonists, U-50,488H and U-62,066E, in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antitussive Agents; Cisterna Magna; Cough; Injections; Ketanserin; Male; Methysergide; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Rats, Inbred Strains; Reflex | 1990 |
Drugs to decrease alcohol drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Extinction, Psychological; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Inbred Strains | 1990 |
Opiate antagonists enhance the working memory of rats in the radial maze.
Topics: Animals; Male; Memory; Memory, Short-Term; Naloxone; Naltrexone; Rats; Retention, Psychology | 1990 |
Enhanced sensitivity to behavioral effects of naltrexone in rats.
Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Rats; Salivation | 1990 |
Opioid agonists and antagonists. 6-Desoxy-6-substituted lactone, epoxide, and glycidate ester derivatives of naltrexone and oxymorphone.
Topics: Animals; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Circular Dichroism; Epoxy Compounds; Ethers, Cyclic; Hydromorphone; Lactones; Male; Naloxone; Naltrexone; Oxymorphone; Propionates; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship | 1985 |
10-Ketonaltrexone and 10-ketooxymorphone.
Topics: Animals; Biological Assay; Brain; Chemical Phenomena; Chemistry; Guinea Pigs; Hydromorphone; Ileum; Male; Mice; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship; Vas Deferens | 1985 |
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones.
Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship | 1985 |
Agonist-antagonist properties of fluorescent opioid probes in the guinea-pig myenteric plexus-longitudinal muscle preparation.
Topics: Animals; Chemical Phenomena; Chemistry; Depression, Chemical; Fluorescent Dyes; Guinea Pigs; Hydromorphone; Ileum; In Vitro Techniques; Male; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Stereoisomerism; Stimulation, Chemical | 1985 |
Action of naloxone on myenteric neurons removed from morphine-treated guinea pigs.
Topics: Acetylcholine; Action Potentials; Animals; Endorphins; Guinea Pigs; Ileum; In Vitro Techniques; Magnesium; Morphine; Muscle Contraction; Myenteric Plexus; Naloxone; Naltrexone; Substance P | 1988 |
Simultaneous extraction and chromatographic analysis of morphine, dilaudid, naltrexone and naloxone in biological fluids by high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Chromatography, High Pressure Liquid; Electrochemistry; Hydromorphone; Male; Morphine; Naloxone; Naltrexone; Rats | 1989 |
Physiologic and plasma hormone correlates of survival in endotoxic dogs: effects of opiate antagonists.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Blood Pressure; Cardiac Output; Dogs; Endotoxins; Epinephrine; Male; Naloxone; Naltrexone; Norepinephrine; Receptors, Opioid; Salmonella typhimurium; Shock, Septic | 1989 |
Analgesia produced by normal doses of opioid antagonists alone and in combination with morphine.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Naltrexone; Pain Measurement; Receptors, Opioid | 1989 |
[Effect of opiate receptor agonists and antagonists on maternal aggression in rats].
Topics: Aggression; Animals; Depression, Chemical; Female; Lactation; Maternal Behavior; Naloxone; Naltrexone; Narcotic Antagonists; Pregnancy; Rats; Receptors, Opioid; Stimulation, Chemical | 1989 |
Naloxone antagonism of corticotropin-releasing hormone stimulation of prolactin secretion in rhesus monkeys.
Topics: Animals; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; Female; Macaca mulatta; Naloxone; Naltrexone; Narcotic Antagonists; Ovariectomy; Prolactin; Receptors, Opioid; Time Factors | 1989 |
Modulation of appetitively and aversively motivated behavior by the kappa opioid antagonist MR2266.
Topics: Animals; Appetitive Behavior; Arousal; Avoidance Learning; Benzomorphans; Brain; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Fear; Female; Injections, Intraventricular; Morphinans; Motivation; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1989 |
Effects of selective opioid-receptor blockade on the hypothalamo-pituitary-adrenocortical responses to surgical trauma in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Benzomorphans; Corticosterone; Dose-Response Relationship, Drug; Enkephalin, Leucine; Hypothalamo-Hypophyseal System; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological | 1989 |
Effects of opiate antagonists and their quaternary analogues on nucleus accumbens self-stimulation.
Topics: Animals; Brain Mapping; Male; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oxymorphone; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Opioid; Self Stimulation; Septal Nuclei | 1989 |
Inhibition of vagal transmission by cardiac sympathetic nerve stimulation in the dog: possible involvement of opioid receptor.
Topics: Blood Pressure; Electric Stimulation; Enkephalin, Leucine; Heart; Heart Rate; Methacholine Chloride; Methacholine Compounds; Naloxone; Naltrexone; Norepinephrine; Prazosin; Receptors, Opioid; Sympathetic Nervous System; Synaptic Transmission; Vagus Nerve; Yohimbine | 1989 |
Pharmacological characterization of supersensitivity to naltrexone in squirrel monkeys.
Topics: Animals; Azocines; Behavior, Animal; Benzomorphans; Diprenorphine; Drug Administration Schedule; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Saimiri | 1989 |
Effects of opioid receptor antagonists on morphine-induced stupor in rabbits.
Topics: Animals; Coma; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rabbits; Receptors, Opioid | 1989 |
The therapeutic efficacy of opiate antagonists in hemorrhagic shock.
Topics: Animals; Dogs; Endorphins; Hemodynamics; Morphinans; Nalbuphine; Naloxone; Naltrexone; Shock, Hemorrhagic | 1989 |
Effects of the selective kappa opioid antagonist, nor-binaltorphimine, on electrically-elicited feeding in the rat.
Topics: Animals; Brain; Eating; Electric Stimulation; Hypothalamus; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1989 |
Modulation of mu-mediated antinociception by delta agonists: characterization with antagonists.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Kappa opioid receptors of human placental villi modulate acetylcholine release.
Topics: Acetylcholine; Chorionic Villi; Diltiazem; Female; Humans; In Vitro Techniques; Kinetics; Morphine; Naloxone; Naltrexone; Pregnancy; Receptors, Opioid; Receptors, Opioid, kappa | 1989 |
Role of central opiate receptor subtypes in the circulatory responses of awake rabbits to graded caval occlusions.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzomorphans; Blood Circulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Hemodynamics; Hemorrhage; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Rabbits; Receptors, Opioid; Vena Cava, Inferior | 1989 |
Lack of mixed agonist-antagonist properties of [Gln8-Gly31]-beta h-EP-Gly-Gly-NH2 and [Arg9,19,24,28,29]-beta h-EP in the rat vas deferens neuroeffector junction: studies with naloxone, beta-funaltrexamine and ICI 174,864.
Topics: Animals; beta-Endorphin; Endorphins; Enkephalin, Leucine; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Neuroeffector Junction; Rats; Rats, Inbred Strains; Vas Deferens | 1989 |
Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Brain; Conditioning, Operant; Enkephalin, Leucine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Somatostatin | 1989 |
Hypothermia elicited by some prodynorphin-derived peptides: opioid and non-opioid actions.
Topics: Animals; Benzomorphans; Body Temperature; Dynorphins; Endorphins; Hypothermia; Kinetics; Male; Motor Activity; Naloxone; Naltrexone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid | 1989 |
Intracerebroventricular physostigmine-induced analgesia: enhancement by naloxone, beta-funaltrexamine and nor-binaltorphimine and antagonism by dynorphin A (1-17).
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Physostigmine; Time Factors | 1989 |
The narcotic antagonist naltrexone has a biphasic effect on the nicotinic acetylcholine receptor.
Topics: Acetylcholine; Animals; Electric Conductivity; Ion Channels; Naloxone; Naltrexone; Rats; Receptors, Cholinergic | 1985 |
Chloroacryloyl amides and alpha-methylenelactones from naltrexone, oxymorphone and fentanyl.
Topics: Acrylates; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Fentanyl; Hydromorphone; In Vitro Techniques; Membranes; Naloxone; Naltrexone; Oxymorphone; Rats; Stereoisomerism | 1985 |
Simultaneous identification and quantification of several opiates and derivatives by capillary gas chromatography and nitrogen selective detection.
Topics: Chromatography, Gas; Humans; Nalorphine; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders | 1989 |
The implication of opiates in the glucocorticoid-mediated inhibition of LH secretion in rats.
Topics: Animals; Corticosterone; Dexamethasone; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Orchiectomy; Pituitary Hormone-Releasing Hormones; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1989 |
Comparison of the duration of action of nalmefene and naloxone on the hypothalamic-pituitary axis of the rhesus monkey.
Topics: Animals; Female; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Macaca mulatta; Naloxone; Naltrexone; Prolactin; Time Factors | 1989 |
Effects of naloxone and naltrexone on memory consolidation in CD1 mice: involvement of GABAergic mechanisms.
Topics: Animals; Avoidance Learning; Bicuculline; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Naltrexone; Picrotoxin | 1989 |
Opioids in the systemic hemodynamic and renal responses to stress in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Consciousness; Endorphins; Hemodynamics; Hypertension; Kidney; Male; Naloxone; Naltrexone; Narcotic Antagonists; Natriuresis; Quaternary Ammonium Compounds; Rats; Rats, Inbred SHR; Stress, Physiological | 1989 |
Delayed suppression of serum luteinizing hormone after naloxone treatment in neonatal female rats.
Topics: Animals; Animals, Newborn; Female; Luteinizing Hormone; Morphine; Naloxone; Naltrexone; Pain; Rats; Rats, Inbred Strains; Secretory Rate; Time Factors | 1989 |
Opiate antagonist treatment reinstates estrous cycles in middle-aged persistent-estrous rats.
Topics: Aging; Animals; Endorphins; Estrus; Female; Luteinizing Hormone; Naloxone; Naltrexone; Rats | 1989 |
Opiate antagonists and self-stimulation: extinction-like response patterns suggest selective reward deficit.
Topics: Animals; Endorphins; Male; Naloxone; Naltrexone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Stimulation; Septal Nuclei | 1989 |
Opioid modulation of feeding and drinking in fowls.
Topics: Animals; Chickens; Drinking; Eating; Enkephalin, Methionine; Female; Injections, Intramuscular; Injections, Intravenous; Injections, Intraventricular; Naloxone; Naltrexone; Time Factors | 1989 |
Comparison of high-dose opioid antagonist effects on ovine fetal cardiovascular function.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Fetus; Gestational Age; Heart Rate; Levallorphan; Naloxone; Naltrexone; Sheep | 1989 |
Does the blockade of opioid receptors influence the development of ethanol dependence?
Topics: Alcoholism; Animals; Diprenorphine; Female; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures; Substance Withdrawal Syndrome | 1987 |
Effects of beta-funaltrexamine on radiolabeled opioid binding.
Topics: Animals; Binding, Competitive; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1987 |
Covalent labeling of mu opioid binding site by [3H]beta-funaltrexamine.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, Affinity; Corpus Striatum; Electrophoresis, Polyacrylamide Gel; Kinetics; Ligands; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Temperature; Time Factors | 1987 |
Opiate receptors and the endorphin-mediated cardiovascular effects of clonidine in rats: evidence for hypertension-induced mu-subtype to delta-subtype changes.
Topics: Animals; Blood Pressure; Clonidine; Endorphins; Enkephalin, Leucine; Heart Rate; Hypertension; Male; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Chronic morphine upregulates a mu-opiate binding site labeled by [3H]cycloFOXY: a novel opiate antagonist suitable for positron emission tomography.
Topics: Alkylating Agents; Animals; Binding, Competitive; Drug Tolerance; Enkephalin, Leucine; In Vitro Techniques; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tomography, Emission-Computed | 1987 |
Stereochemistry of novel delta selective opiate antagonists.
Topics: Estrone; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Naloxone; Naltrexone; Pregnenolone; Receptors, Opioid; Receptors, Opioid, delta; X-Ray Diffraction | 1986 |
Opioid components of the clockwork that governs luteinizing hormone and prolactin release in male rats.
Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Endorphins; Ligands; Luteinizing Hormone; Male; Naloxone; Naltrexone; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1988 |
beta-FNA binds irreversibly to the opiate receptor complex: in vivo and in vitro evidence.
Topics: Animals; Binding Sites; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1988 |
Influence of neonatal opioid blockade or injections of gonadotrophin-releasing hormone on the timing of puberty in female rats: correlation of opioid effects with occupation of hypothalamic mu-opioid receptors.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Hypothalamus; Naloxone; Naltrexone; Pituitary Hormone-Releasing Hormones; Rats; Receptors, Opioid; Receptors, Opioid, mu; Sexual Maturation; Time Factors | 1988 |
Emergence and development of stress-induced analgesia and concomitant behavioral changes in mice exposed to social conflict.
Topics: Aggression; Agonistic Behavior; Animals; Arousal; Brain; Conflict, Psychological; Escape Reaction; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Naloxone; Naltrexone; Nociceptors; Receptors, Opioid; Social Environment | 1988 |
Lack of evidence for epsilon-opioid receptors in the rat vas deferens.
Topics: Animals; Calcium; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Vas Deferens | 1988 |
Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.
Topics: Animals; Benzomorphans; Caudate Nucleus; Dopamine; Male; Methadone; Morphine; Motor Activity; Naloxone; Naltrexone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Septal Nuclei | 1988 |
Inhibition by opioid agonists and enhancement by antagonists of the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation: evidence for the functional role of opioid receptors.
Topics: Adrenal Glands; Animals; Catecholamines; Dogs; Electric Stimulation; Enkephalin, Leucine; Female; Male; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Splanchnic Nerves | 1988 |
Treatment of stroke with opiate antagonists--effects of exogenous antagonists and dynorphin 1-13.
Topics: Acute Disease; Animals; Brain Ischemia; Cats; Dynorphins; Enkephalin, Leucine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments | 1985 |
Simultaneous quantitation of norepinephrine, dopamine and serotonin in brain during and following chronic naltrexone administration.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Female; Naloxone; Naltrexone; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Time Factors | 1985 |
An analysis of naltrexone and naloxone's possible agonistic actions in the dog.
Topics: Analgesics, Opioid; Animals; Cyclazocine; Dogs; Drug Synergism; Electroencephalography; Ethylketocyclazocine; Evoked Potentials; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Reaction Time; Reflex; Reflex, Pupillary | 1985 |
Chronic desipramine attenuates morphine analgesia.
Topics: Analgesics, Opioid; Animals; Desipramine; Drug Interactions; Male; Mice; Morphine; Naloxone; Naltrexone; Propranolol; Reaction Time | 1986 |
Opiate antagonists do not alter neuronal responses to stimulation of opioid-containing pathways in rat hippocampus.
Topics: Animals; Dynorphins; Endorphins; Evoked Potentials; Hippocampus; In Vitro Techniques; Naloxone; Naltrexone; Peptide Fragments; Rats; Synaptic Transmission | 1986 |
[Frequency as the cardinal determinant for electroacupuncture analgesia to be reversed by opioid antagonists].
Topics: Acupuncture Therapy; Animals; beta-Endorphin; Dynorphins; Electric Stimulation Therapy; Endorphins; Enkephalins; Naloxone; Naltrexone; Pain; Rats; Sensory Thresholds; Transcutaneous Electric Nerve Stimulation | 1986 |
Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Chemical Phenomena; Chemistry; Cyclazocine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa | 1987 |
An examination of the opiate receptor subtypes labeled by [3H]cycloFOXY: an opiate antagonist suitable for positron emission tomography.
Topics: Animals; Autoradiography; Brain; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Membranes; Tomography, Emission-Computed | 1988 |
High doses of L-naloxone but neither D-naloxone nor beta-funaltrexamine prevent hyperthermia-induced seizures in rat pups.
Topics: Animals; Body Temperature; Hyperthermia, Induced; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism | 1988 |
Endorphins in primate hemorrhagic shock: beneficial action of opiate antagonists.
Topics: Animals; beta-Endorphin; Disease Models, Animal; Dose-Response Relationship, Drug; Endorphins; Female; Hemodynamics; Naloxone; Naltrexone; Narcotic Antagonists; Papio; Shock, Hemorrhagic; Time Factors | 1986 |
Opioid-mediated cardiovascular effects of clonidine in spontaneously hypertensive rats: elimination by neonatal treatment with monosodium glutamate.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Enkephalin, Leucine; Glutamates; Heart Rate; Hemodynamics; Hypertension; Medulla Oblongata; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Glutamate | 1986 |
Pro-opiomelanocortin-derived peptides in the testis: evidence for a possible role in Leydig and Sertoli cell function.
Topics: Animals; beta-Endorphin; Castration; Cell Differentiation; Chromatography, High Pressure Liquid; Endorphins; Hypophysectomy; Leydig Cells; Male; Naloxone; Naltrexone; Pro-Opiomelanocortin; Progesterone; Rats; Rats, Inbred Strains; RNA, Messenger | 1986 |
Antagonism by naltrexone of the hypotension and bradycardia induced by alpha-methyldopa in conscious normotensive rats.
Topics: Animals; beta-Endorphin; Bradycardia; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Immune Sera; Male; Methyldopa; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1988 |
[Naloxone and naltrexone in the treatment of chronic obstructive bronchopneumopathies].
Topics: Humans; Lung Diseases, Obstructive; Male; Middle Aged; Naloxone; Naltrexone | 1988 |
Possible delta receptor mediation of the effect of beta-endorphin on luteinizing hormone (LH) release, but not on prolactin (PRL) release, in the ovariectomized rat.
Topics: Animals; beta-Endorphin; Castration; Endorphins; Enkephalin, Leucine; Female; Kinetics; Luteinizing Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Neurochemical and functional correlates of naltrexone-induced opiate receptor up-regulation.
Topics: Animals; Brain Chemistry; Guanosine Triphosphate; Male; Morphine; Naloxone; Naltrexone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1985 |
TENA, a selective kappa opioid receptor antagonist.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Azocines; Benzomorphans; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1985 |
Opioid receptor binding characteristics of the non-equilibrium mu antagonist, beta-funaltrexamine (beta-FNA).
Topics: Animals; Brain; Enkephalin, Methionine; In Vitro Techniques; Ligands; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium | 1985 |
Prolonged in vivo antagonism of central mu- and delta-opioid receptor activity by beta-funal trexamine.
Topics: Animals; Female; Injections, Intraventricular; Injections, Spinal; Muscle Contraction; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Urinary Bladder | 1985 |
Chronic naltrexone treatment increases the heroin-produced facilitation of self-stimulation.
Topics: Animals; Drug Synergism; Heroin; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Self Stimulation; Time Factors | 1985 |
Effect of sodium chloride on opiate receptor binding in spontaneously hypertensive rats: dependence on age.
Topics: Animals; Blood Pressure; Brain; Drug Implants; Female; Hypertension; Male; Naloxone; Naltrexone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid; Sodium Chloride | 1985 |
Effects of opiates on urine output in the water-loaded rat and reversal by beta-funaltrexamine.
Topics: Animals; Diuresis; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
Multi-dimensional analyses of behavior in mice treated with naltrexone.
Topics: Animals; Brain; Male; Mice; Mice, Inbred Strains; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid | 1985 |
Effects of 5,5'-dithiobis-(2-nitrobenzoic acid) on opiate binding to both the membrane-bound receptor and the partially purified opiate receptor.
Topics: Animals; Butorphanol; Cell Membrane; Dihydromorphine; Diprenorphine; Dithionitrobenzoic Acid; Dithiothreitol; Etorphine; Morphine; Nalorphine; Naloxone; Naltrexone; Nitrobenzoates; Oxymorphone; Rats; Receptors, Opioid | 1985 |
Plasma corticosterone changes in response to central or peripheral administration of kappa and sigma opiate agonists.
Topics: Animals; Brain; Corticosterone; Cyclazocine; Ethylketocyclazocine; Humans; Hypothalamo-Hypophyseal System; Male; Morphine; Naloxone; Naltrexone; Opioid-Related Disorders; Phenazocine; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1985 |
Increased analgesic potency of morphine and increased brain opioid binding sites in the rat following chronic naltrexone treatment.
Topics: Animals; Binding, Competitive; Brain; Drug Implants; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Morphine; Naloxone; Naltrexone; Pain; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Time Factors | 1985 |
Binding of a new opiate antagonist, nalmefene, to rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; In Vitro Techniques; Kinetics; Membranes; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1985 |
The anticonvulsant effects of DADLE are primarily mediated by activation of delta opioid receptors: interactions between delta and mu receptor antagonists.
Topics: Animals; Anticonvulsants; Cerebral Ventricles; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1985 |
Castration affects male rat brain opiate receptor content.
Topics: Animals; Brain; Castration; Filtration; Male; Naloxone; Naltrexone; Radioligand Assay; Rats; Receptors, Opioid | 1985 |
Opiate antagonism reduces placentophagia and pup cleaning by parturient rats.
Topics: Animals; Drug Tolerance; Feeding Behavior; Female; Labor, Obstetric; Maternal Behavior; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Opioid; Time Factors | 1985 |
Pre-incubation of guinea-pig myenteric plexus with beta-funaltrexamine: discrepancy between binding assays and bioassays.
Topics: Animals; Binding, Competitive; Brain; Cricetinae; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Narcotic Antagonists; Rabbits; Rats; Receptors, Opioid | 1985 |
Radiosynthesis of [18F]3-acetylcyclofoxy: a high affinity opiate antagonist.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorine; Indicators and Reagents; Isotope Labeling; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Radioisotopes; Receptors, Opioid | 1985 |
Effect of mu and kappa opioid receptor agonists on rat plasma corticosterone levels.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Benzomorphans; Corticosterone; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1985 |
Receptors for opioid peptides in the guinea-pig ileum.
Topics: Alkylation; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 1985 |
Analgesic effects of mu antagonists after naloxone non-reversible stress-induced analgesia.
Topics: Analgesics; Animals; Diprenorphine; Electroshock; Male; Nalorphine; Naloxone; Naltrexone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Stress, Physiological | 1985 |
Pharmacological evidence for a protective role of the endogenous opioid system on electroshock-induced seizures in the mouse.
Topics: Animals; Electroshock; Endorphins; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seizures; Time Factors | 1985 |
[3H]beta-funaltrexamine binds covalently to brain opioid receptors.
Topics: Animals; Binding Sites; Cattle; Corpus Striatum; Guinea Pigs; Male; Naloxone; Naltrexone; Receptors, Opioid; Time Factors | 1985 |
Effects of endogenous and exogenous opioids on splenic natural killer cell activity.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cytotoxicity Tests, Immunologic; Electric Stimulation; Endorphins; Female; Injections, Intraperitoneal; Killer Cells, Natural; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Poly I-C; Spleen | 1986 |
Activity of mu- and delta-selective opioid agonists in the guinea pig ileum preparation: differentiation into peptide and nonpeptide classes with beta-funaltrexamine.
Topics: Animals; Endorphins; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Nalorphine; Naloxone; Naltrexone; Narcotics; Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 1986 |
Central, stereoselective receptors mediate the acute effects of opiate antagonists on luteinizing hormone secretion.
Topics: Animals; Brain; Injections, Intraventricular; Luteinizing Hormone; Male; Naloxone; Naltrexone; Quaternary Ammonium Compounds; Rats; Receptors, Opioid; Stereoisomerism | 1986 |
Reversible and irreversible binding of beta-funaltrexamine to mu, delta and kappa opioid receptors in guinea pig brain membranes.
Topics: Animals; Brain; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Ethylmaleimide; Guinea Pigs; Kinetics; Male; Membranes; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Chloride | 1986 |
Evidence for coupling of the kappa opioid receptor to brain GTPase.
Topics: Alkylation; Animals; Brain; Cell Membrane; Cerebellum; Endorphins; GTP Phosphohydrolases; Guinea Pigs; Macaca mulatta; Naloxone; Naltrexone; Phosphoric Monoester Hydrolases; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
An analysis of naltrexone precipitated abstinence in morphine-dependent chronic spinal dogs.
Topics: Animals; Behavior, Animal; Cordotomy; Dogs; Dose-Response Relationship, Drug; Female; Morphine Dependence; Naloxone; Naltrexone; Receptors, Opioid; Substance Withdrawal Syndrome | 1987 |
Evidence for mu opioid receptor mediation of enkephalin-induced electroencephalographic seizures.
Topics: Animals; Electroencephalography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1987 |
The pattern of [3H]cyclofoxy retention in rat brain after in vivo injection corresponds to the in vitro opiate receptor distribution.
Topics: Animals; Autoradiography; Brain; Cerebellum; Densitometry; Image Processing, Computer-Assisted; Injections; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Tissue Distribution; Tritium | 1987 |
Brain opioids and autism: an updated analysis of possible linkages.
Topics: Autistic Disorder; Brain; Brain Damage, Chronic; Child; Emotions; Endorphins; Humans; Language Development Disorders; Naloxone; Naltrexone; Receptors, Opioid; Serotonin; Social Behavior | 1987 |
Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L.
Topics: Analgesics; Animals; Benzomorphans; Cannabis; Dose-Response Relationship, Drug; Enkephalin, Leucine; Haplorhini; Hydroxydopamines; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oxidopamine; Plant Extracts; Rats; Rats, Inbred Strains | 1986 |
Naloxone and naltrexone. Application in COPD.
Topics: Aged; Carbon Dioxide; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Naloxone; Naltrexone; Oxygen | 1988 |
Role of endogenous opioids on ventilation and chemical control of breathing in pentobarbitone-anesthetized rats.
Topics: Anesthesia; Animals; Blood Gas Analysis; Carbon Dioxide; Endorphins; Hydrogen-Ion Concentration; Hypoxia; Injections, Intraventricular; Male; Naloxone; Naltrexone; Pentobarbital; Rats; Respiration; Respiratory Function Tests | 1987 |
"Paradoxical" analgesia induced by naloxone and naltrexone.
Topics: Analgesics; Animals; Behavior, Animal; Delayed-Action Preparations; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1988 |
Evaluation of the anti-arrhythmic potency of naltrexone in the isolated ischaemic rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Disease; Female; In Vitro Techniques; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1988 |
Endogenous opioid systems and neural cancer: transmission and scanning electron microscopic studies of murine neuroblastoma in tissue culture.
Topics: Enkephalin, Methionine; Male; Microscopy, Electron, Scanning; Naloxone; Naltrexone; Neuroblastoma; Time Factors; Tumor Cells, Cultured | 1988 |
Effects of opioid peptides on aldosterone production: stimulatory effect of leu-enkephalin.
Topics: Adrenal Cortex; Aldosterone; Animals; Cattle; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Naloxone; Naltrexone; Perfusion | 1988 |
Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates.
Topics: Animals; Colon; Constipation; Diarrhea; Dose-Response Relationship, Drug; Glucuronates; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Skin Temperature; Substance-Related Disorders | 1988 |
Opioidergic modulation of the oestradiol-induced LH surge in the rat: roles of ovarian steroids.
Topics: Animals; Diestrus; Estradiol; Female; Luteinizing Hormone; Naloxone; Naltrexone; Ovariectomy; Proestrus; Progesterone; Rats; Rats, Inbred Strains | 1988 |
Acute supersensitivity to the discriminative stimulus effects of naltrexone in pigeons.
Topics: Animals; Binding Sites; Columbidae; Diprenorphine; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Stimulus; Morphine; Nalorphine; Naloxone; Naltrexone; Opioid-Related Disorders | 1988 |
Effects of treatment with the opioid antagonists naloxone and naltrexone on LH secretion and on sexual maturation in immature female rats.
Topics: Animals; Animals, Newborn; Female; Luteinizing Hormone; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Sexual Maturation; Time Factors | 1988 |
Comparative evaluation of different pathways for the liver toxicity of morphine using freshly isolated hepatocytes.
Topics: Animals; Glutathione; Liver; Male; Metyrapone; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1988 |
Evidence for the involvement of central opioidergic systems in L-tyrosine methyl ester-induced analgesia in the rat.
Topics: Analgesia; Animals; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Long-term analgesic reaction in attacked mice.
Topics: Aggression; Analgesia; Animals; Bites and Stings; Endorphins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Naloxone; Naltrexone; Narcotic Antagonists | 1987 |
Chronic antagonist infusion does not increase morphine antinociception in rat spinal cord.
Topics: Animals; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord | 1987 |
Effects of narcotic antagonists on self-injurious behavior: a single case study.
Topics: Adolescent; Humans; Male; Naloxone; Naltrexone; Self Mutilation | 1987 |
Endogenous opioids and post-ictal increase in seizure threshold in Mongolian gerbils.
Topics: Animals; Electric Stimulation; Endorphins; Gerbillinae; Morphine; Naloxone; Naltrexone; Pentylenetetrazole; Seizures | 1987 |
Effect of endorphins on heart rate and blood pressure in adult dogs.
Topics: Animals; Atropine; Blood Pressure; Consciousness; Dogs; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Heart; Heart Rate; Naloxone; Naltrexone | 1986 |
Opioid and non-opioid components of insulin-induced feeding.
Topics: Animals; Blood Glucose; Brain; Drug Interactions; Endorphins; Feeding Behavior; Insulin; Male; Mice; Naloxone; Naltrexone | 1986 |
Conditioned fear-induced opiate analgesia: a competing motivational state theory of stress analgesia.
Topics: Analgesia; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Endorphins; Fear; Formaldehyde; Models, Biological; Motor Activity; Naloxone; Naltrexone; Nociceptors; Sensory Thresholds; Shock; Stress, Physiological | 1986 |
Effects of naloxone and naltrexone on meal patterns of freely-feeding rats.
Topics: Animals; Circadian Rhythm; Feeding Behavior; Male; Naloxone; Naltrexone; Rats; Time Factors | 1987 |
Evidence for opioid and non-opioid forms of stress-induced analgesia in the snail, Cepaea nemoralis.
Topics: Animals; Cold Temperature; Endorphins; Enkephalin, Leucine; Hot Temperature; Naloxone; Naltrexone; Pain; Reaction Time; Snails; Stress, Physiological | 1987 |
[Effects of the opiate antagonists naloxone and naltrexone on the body temperature of rats].
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Drug Interactions; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Nitrous oxide-induced hypothermia in the rat.
Topics: Animals; Body Temperature; Chloral Hydrate; Dose-Response Relationship, Drug; Drug Tolerance; Kinetics; Male; Morphine; Naloxone; Naltrexone; Nitrous Oxide; Rats | 1987 |
The effects of opioid antagonists on ingestive behavior in the domestic fowl.
Topics: Animals; Chickens; Drinking Behavior; Feeding Behavior; Naloxone; Naltrexone | 1987 |
Immediate and long-term effects of opiate antagonists on postictal behaviour following amygdala kindling in the rat.
Topics: Amygdala; Animals; Behavior, Animal; Electric Stimulation; Kindling, Neurologic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Seizures | 1987 |
Antagonism by nalmefene of systemic and intrathecal morphine-induced analgesia in mice.
Topics: Analgesia; Animals; Injections, Intravenous; Injections, Spinal; Male; Mice; Morphine; Naloxone; Naltrexone; Time Factors | 1987 |
Strain differences in reversal of conditional analgesia by opioid antagonists.
Topics: Analgesia; Animals; Conditioning, Psychological; Female; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Species Specificity | 1987 |
Antagonism of endogenous opioids modulates memory processing.
Topics: Animals; Anisomycin; Avoidance Learning; Dose-Response Relationship, Drug; Electroshock; Endorphins; Learning; Male; Memory; Mice; Naloxone; Naltrexone; Scopolamine | 1987 |
Hypotensive effect of naloxone on high blood pressure induced by stress in the rat.
Topics: Acoustic Stimulation; Animals; Blood Pressure; Cold Temperature; Electroshock; Hypertension; Male; Naloxone; Naltrexone; Photic Stimulation; Rats; Rats, Inbred Strains; Social Isolation; Stress, Physiological; Stress, Psychological | 1987 |
The effects of opioid receptor antagonists suggest that testicular opiates regulate Sertoli and Leydig cell function in the neonatal rat.
Topics: Androgen-Binding Protein; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Endorphins; Hypertrophy; Leydig Cells; Male; Naloxone; Naltrexone; Orchiectomy; Rats; Rats, Inbred Strains; Sertoli Cells; Testis; Testosterone | 1986 |
Evidence for a central but not adrenal, opioid mediation in hypertension induced by brief isolation in the rat.
Topics: Adrenalectomy; Animals; Blood Pressure; Corticosterone; Endorphins; Gastrointestinal Motility; Male; Morphine; Nalorphine; Naloxone; Naltrexone; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Social Isolation; Stress, Physiological | 1986 |
Endogenous analgesia in the pregnant rat: an artifact of weight-dependent measures?
Topics: Animals; Body Weight; Endorphins; Female; Naloxone; Naltrexone; Pain; Postpartum Period; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Sensory Thresholds | 1986 |
Comparison of the effects of morphine and immobilization stress on discrimination performance of rats.
Topics: Animals; Arousal; Attention; Conditioning, Operant; Discrimination, Psychological; Electroshock; Male; Morphine; Naloxone; Naltrexone; Orientation; Psychomotor Performance; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Psychological | 1986 |
Effect of naloxone and naltrexone on the development of satiation measured in the runway: comparisons with d-amphetamine and d-fenfluramine.
Topics: Animals; Dextroamphetamine; Endorphins; Feeding Behavior; Fenfluramine; Male; Naloxone; Naltrexone; Rats; Reaction Time; Satiation | 1986 |
Low-level microwave irradiations affect central cholinergic activity in the rat.
Topics: Animals; Brain; Choline; Frontal Lobe; Hippocampus; Male; Microwaves; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Sodium | 1987 |
Naloxone, naltrexone and body temperature.
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Kinetics; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1987 |
Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse.
Topics: Animals; Behavior, Animal; Female; Horses; Male; Naloxone; Naltrexone; Narcotic Antagonists | 1987 |
[Naloxone and naltrexone antagonism of various central effects of morphine].
Topics: Animals; Behavior, Animal; Central Nervous System; Female; Male; Mice; Morphine; Naloxone; Naltrexone; Pain Measurement; Rats; Substance Withdrawal Syndrome | 1986 |
[Activity of naloxone and naltrexone on the development of the morphine withdrawal syndrome].
Topics: Animals; Behavior, Animal; Female; Male; Mice; Morphine Dependence; Naloxone; Naltrexone; Rats; Substance Withdrawal Syndrome | 1986 |
Unexpected effects of nalmefene, a new opiate antagonist, on the hypothalamic-pituitary-gonadal axis in the male rat.
Topics: Animals; Dose-Response Relationship, Drug; Feedback; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Naloxone; Naltrexone; Rats; Testosterone; Time Factors | 1985 |
Exposure to a cat produces opioid analgesia in rats.
Topics: Animals; Endorphins; Fear; Female; Naloxone; Naltrexone; Nervous System; Pain; Rats; Rats, Inbred Strains; Reaction Time | 1985 |
Historical introduction and review of chemistry.
Topics: Analgesics; Chemistry; History, 20th Century; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Phenazocine | 1985 |
Antinociceptive models displaying peripheral opioid activity.
Topics: Analgesics; Animals; Carrageenan; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Epoprostenol; Female; Indomethacin; Mice; Morphine; Movement; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists | 1985 |
Blockade by naloxone and naltrexone of the TRH-induced stimulation of colonic transit in the rabbit.
Topics: Animals; Colon; Gastrointestinal Motility; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rabbits; Serotonin; Thyrotropin-Releasing Hormone | 1985 |
Effects of morphine, naltrexone, and dextrorphan in untreated and morphine-treated pigeons.
Topics: Animals; Behavior, Animal; Body Weight; Columbidae; Conditioning, Operant; Dextrorphan; Dose-Response Relationship, Drug; Drug Tolerance; Morphinans; Morphine; Naloxone; Naltrexone; Stereoisomerism | 1985 |
Treatment of experimental stroke with opiate antagonists. Effects on neurological function, infarct size, and survival.
Topics: Animals; Brain Ischemia; Cats; Cerebrovascular Disorders; Consciousness; Diprenorphine; Disease Models, Animal; Male; Morphinans; Movement; Naloxone; Naltrexone; Pupil; Sensation | 1986 |
Independent central and peripheral mediation of morphine-induced inhibition of gastrointestinal transit in rats.
Topics: Analgesia; Animals; Brain; Gastrointestinal Motility; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Naloxone; Naltrexone; Peripheral Nerves; Rats; Rats, Inbred Strains | 1986 |
Naltrexone for opioid addiction.
Topics: Drug Interactions; Humans; Kinetics; Naloxone; Naltrexone; Opioid-Related Disorders; Socioeconomic Factors | 1985 |
Naltrexone facilitation of sexual receptivity in the rat.
Topics: Adrenalectomy; Animals; Anisomycin; Castration; Drug Interactions; Endorphins; Female; Naloxone; Naltrexone; Pargyline; Posture; Rats; Sexual Behavior, Animal | 1985 |
Pharmacokinetics of morphine and its surrogates V: Naltrexone and naltrexone conjugate pharmacokinetics in the dog as a function of dose.
Topics: Animals; Bile; Body Fluids; Chromatography, High Pressure Liquid; Dogs; Kidney; Kinetics; Liver; Morphine; Naloxone; Naltrexone | 1985 |
Antagonism of brain opioid peptide action reduces hibernation bout duration.
Topics: Animals; Endorphins; Hibernation; Injections, Intraventricular; Injections, Subcutaneous; Naloxone; Naltrexone; Sciuridae | 1985 |
Naltrexone fails to suppress spontaneous locomotor activity in hamsters.
Topics: Animals; Cricetinae; Environment; Exploratory Behavior; Male; Mesocricetus; Mice; Motor Activity; Naloxone; Naltrexone; Rats; Species Specificity; Time Factors | 1985 |
Naltrexone's influence on neurobehavioral development.
Topics: Animals; Behavior, Animal; Body Weight; Female; Male; Motor Activity; Naloxone; Naltrexone; Nervous System; Nociceptors; Psychomotor Performance; Rats; Rats, Inbred Strains; Reflex; Time Factors; Weaning | 1985 |
Hot-plate learning in mice is unaltered by immediate post-training administration of naloxone, naltrexone or morphine.
Topics: Animals; Endorphins; Hot Temperature; Learning; Male; Memory; Mice; Morphine; Naloxone; Naltrexone; Pain | 1985 |
Opioid antagonist-induced regulation of organ development.
Topics: Animals; Animals, Suckling; Female; Growth; Male; Naloxone; Naltrexone; Organ Size; Organ Specificity; Rats; Rats, Inbred Strains; Sex Factors | 1985 |
Effects of opioids and phencyclidine in combination with naltrexone on the acquisition and performance of response sequences in monkeys.
Topics: Animals; Cyclazocine; Dose-Response Relationship, Drug; Erythrocebus patas; Female; Heroin; Methadone; Naloxone; Naltrexone; Narcotics; Phencyclidine; Reinforcement Schedule; Serial Learning | 1985 |
Endogenous opiates participate in the regulation of pulsatile luteinizing hormone release in an unopposed estrogen milieu: studies in estrogen-replaced, gonadectomized patients with testicular feminization.
Topics: Adolescent; Adult; Androgen-Insensitivity Syndrome; Castration; Endorphins; Estradiol; Estrogens; Female; Humans; Luteinizing Hormone; Naloxone; Naltrexone | 1985 |
Narcotic antagonist-induced hypotension in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stereoisomerism | 1985 |
Discriminative stimulus effects of morphine withdrawal in the dependent rat: suppression by opiate and nonopiate drugs.
Topics: Animals; Body Weight; Clonidine; Haloperidol; Humans; Male; Morphine Dependence; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Stereoisomerism; Substance Withdrawal Syndrome | 1985 |
Hyperthermia in the rat from handling stress blocked by naltrexone injected into the preoptic-anterior hypothalamus.
Topics: Animals; Body Temperature; Brain; Handling, Psychological; Humans; Hypothalamic Area, Lateral; Hypothalamus, Anterior; Injections; Injections, Intraperitoneal; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Stress, Psychological | 1985 |
Effects of naloxone and other opiate antagonists on blood-ethanol concentration in acutely-ethanol-intoxicated rats.
Topics: Alcoholic Intoxication; Animals; Benzomorphans; Ethanol; Humans; Male; Morphinans; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Naltrexone antagonizes the biobehavioral adaptation to cold water stress in rats.
Topics: Adaptation, Physiological; Animals; Body Temperature; Central Nervous System; Cold Temperature; Endorphins; Male; Naloxone; Naltrexone; Neuronal Plasticity; Pain; Rats; Rats, Inbred Strains; Reaction Time; Stress, Physiological | 1985 |
Narcotic antagonist potentiation of apomorphine drug effect: a stereospecific, centrally mediated drug action.
Topics: Animals; Apomorphine; Drug Synergism; Exploratory Behavior; Humans; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Stereoisomerism; Stereotyped Behavior | 1985 |
Cross-tolerance between morphine- and bombesin-induced inhibition of intestinal transit in rats.
Topics: Animals; Bombesin; Drug Tolerance; Gastrointestinal Motility; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1985 |
Effects of buprenorphine on shock titration in squirrel monkeys.
Topics: Animals; Buprenorphine; Conditioning, Operant; Diprenorphine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Male; Morphinans; Morphine; Naloxone; Naltrexone; Saimiri | 1985 |
Effects of beta-funaltrexamine in normal and morphine-dependent rhesus monkeys: observational studies.
Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Macaca mulatta; Morphine; Muscle Relaxation; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1985 |
Antagonistic and rate-suppressing effects of opioid antagonists in the pigeon.
Topics: Animals; Azocines; Benzomorphans; Buprenorphine; Columbidae; Conditioning, Operant; Diprenorphine; Dose-Response Relationship, Drug; Morphine; Naloxone; Naltrexone; Narcotic Antagonists | 1985 |
Asymmetric behavior induced by enkephalinergic agents in the basal ganglia.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Ganglia, Spinal; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1985 |
Intracerebroventricular drug administration in pigeons.
Topics: Animals; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Injections, Intramuscular; Injections, Intraventricular; Morphine; Naloxone; Naltrexone; Pharmaceutical Preparations | 1985 |
Effects of opioid antagonists and their quaternary derivatives on locomotor activity and fixed ratio responding for brain self-stimulation in rats.
Topics: Animals; Brain Mapping; Conditioning, Operant; Male; Mesencephalon; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Reinforcement Schedule; Self Stimulation | 1985 |
Effects of opiate antagonists on spatial memory in young and aged rats.
Topics: Age Factors; Aging; Animals; Diprenorphine; Male; Memory; Naloxone; Naltrexone; Rats; Space Perception; Stimulation, Chemical | 1985 |
Effects of opiate antagonists on feeding and spontaneous locomotion in deer.
Topics: Animals; Brain; Deer; Endorphins; Feeding Behavior; Female; Male; Motor Activity; Naloxone; Naltrexone; Seasons | 1985 |
Clinical use of naltrexone (EN-1639A): Part I: Safety and efficacy in pilot studies.
Topics: Adult; Ambulatory Care; Drug Evaluation; Female; Heroin Dependence; Humans; Legislation, Drug; Male; Middle Aged; Naloxone; Naltrexone; Nausea; New York City; Pilot Projects; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; United States | 1974 |
Stereospecificity of 4,5-epoxymorphinan binding to the lambda site in rat brain.
Topics: Animals; Binding, Competitive; Brain; In Vitro Techniques; Male; Morphinans; Morphine; Naloxone; Naltrexone; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism | 1984 |
Duration of opiate receptor blockade determines tumorigenic response in mice with neuroblastoma: a role for endogenous opioid systems in cancer.
Topics: Analgesia; Animals; Cell Line; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Neuroblastoma; Receptors, Opioid | 1984 |
Naltrexone in addicted business executives and physicians.
Topics: Administrative Personnel; Adult; Aftercare; Ambulatory Care; Clonidine; Commerce; Female; Hospitalization; Humans; Male; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Compliance; Physician Impairment | 1984 |
Effect of beta-FNA on opiate delta receptor binding.
Topics: Animals; Brain; Cell Membrane; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Naloxone; Naltrexone; Oligopeptides; Protein Conformation; Rats; Receptors, Opioid | 1984 |
Design and synthesis of naltrexone-derived affinity labels with nonequilibrium opioid agonist and antagonist activities. Evidence for the existence of different mu receptor subtypes in different tissues.
Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Male; Mice; Morphine; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, mu; Structure-Activity Relationship; Vas Deferens | 1984 |
Enhancement of opiate-induced depressions in serum luteinizing hormone levels by the prior administration of naloxone in the male rat.
Topics: Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Male; Morphine; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Antagonism of diazepam-induced feeding in rats by antisera to opioid peptides.
Topics: Animals; beta-Endorphin; Dexamethasone; Diazepam; Endorphins; Enkephalin, Methionine; Feeding Behavior; Immune Sera; Male; Naloxone; Naltrexone; Pituitary Gland; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1984 |
Counteraction by naltrexone of stress-induced inhibition of TSH release: role of noradrenergic system.
Topics: Animals; Ditiocarb; Kinetics; Male; Morphine; Naloxone; Naltrexone; Norepinephrine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Stress, Physiological; Thyrotropin | 1984 |
Cold water stress analgesia in rats: differential effects of naltrexone.
Topics: Animals; Arousal; Body Temperature Regulation; Cold Temperature; Male; Naloxone; Naltrexone; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Stress, Physiological | 1984 |
Naltrexone modulates body and brain development in rats: a role for endogenous opioid systems in growth.
Topics: Aging; Animals; Body Weight; Brain; Female; Male; Naloxone; Naltrexone; Organ Size; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Opiate-receptor interactions on single locus coeruleus neurones.
Topics: Action Potentials; Animals; Enkephalin, Methionine; In Vitro Techniques; Locus Coeruleus; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Rats; Receptors, Opioid | 1984 |
Mu and delta opioid receptor interactions in a rat model of drug induced seizures.
Topics: Animals; Disease Models, Animal; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1984 |
Effects of ethanol and naltrexone on free-operant avoidance behavior in rats.
Topics: Animals; Avoidance Learning; Conditioning, Operant; Drug Combinations; Ethanol; Food Deprivation; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Clonidine hydrochloride detoxification from methadone treatment--the value of naltrexone aftercare.
Topics: Adult; Aftercare; Attitude to Health; Clonidine; Female; Follow-Up Studies; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1984 |
Hyperthermic response of the cat to intraventricular injection of the opioid delta-receptor agonist D-Ala2-D-Leu5-enkephalin.
Topics: Animals; Body Temperature; Body Temperature Regulation; Cats; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta | 1984 |
Comparative antagonism by naltrexone and naloxone of mu, kappa, and delta agonists.
Topics: Animals; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
3-[18F]Acetylcyclofoxy: a useful probe for the visualization of opiate receptors in living animals.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Cell Membrane; Fluorine; Naloxone; Naltrexone; Radioisotopes; Rats; Receptors, Opioid; Tissue Distribution | 1984 |
Chronic naloxone increases opiate binding in SHR and WKY rats.
Topics: Aging; Animals; Blood Pressure; Brain; Female; Kinetics; Male; Naloxone; Naltrexone; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid | 1984 |
Chronic blockade of opiate receptors: influence on reproduction and body weight in female rats.
Topics: Animals; Body Weight; Estrus; Female; Luteinizing Hormone; Naloxone; Naltrexone; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Opioid; Reproduction | 1984 |
Core temperature changes following administration of naloxone and naltrexone to rats exposed to hot and cold ambient temperatures. Evidence for the physiological role of endorphins in hot and cold acclimatization.
Topics: Animals; Body Temperature Regulation; Cold Temperature; Endorphins; Hot Temperature; Male; Naloxone; Naltrexone; Rats | 1980 |
Interactions between narcotic agonists, partial agonists and antagonists evaluated by schedule-controlled behavior.
Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Drug Interactions; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Reaction Time; Reinforcement Schedule | 1980 |
Effects of naltrexone and prolyl-leucyl-glycinamide on drug-induced tremor and rigidity in the rat.
Topics: Animals; Female; Injections, Intraventricular; Morphine; MSH Release-Inhibiting Hormone; Muscle Rigidity; Muscle Tonus; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Time Factors; Tremor; Tremorine | 1981 |
Anorexic effects of naltrexone in man.
Topics: Adolescent; Adult; Anorexia; Body Weight; Feeding and Eating Disorders; Female; Humans; Male; Naloxone; Naltrexone | 1982 |
Pharmacological characterization in vivo of the novel opiate, beta-funaltrexamine.
Topics: Acetates; Acetic Acid; Analgesics, Opioid; Animals; Drug Interactions; Female; Male; Mice; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotics; Pain; Reaction Time | 1982 |
Naloxone: analeptic action unrelated to opiate receptor antagonism?
Topics: Animals; Central Nervous System Stimulants; Halothane; Injections, Intraventricular; Ketamine; Male; Naloxone; Naltrexone; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Opioid; Sleep | 1982 |
Prevention of late fentanyl-induced respiratory depression after the injection of opiate antagonists naltrexone and S-20682: comparison with naloxone.
Topics: Animals; Carbon Dioxide; Depression, Chemical; Dogs; Electroencephalography; Fentanyl; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oxygen; Partial Pressure; Respiration; Time Factors | 1983 |
Opioid peptides inhibit intestinal transit in the rat by a central mechanism.
Topics: Animals; beta-Endorphin; Central Nervous System; Diarrhea; Dynorphins; Endorphins; Female; Gastrointestinal Motility; Intestine, Small; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1982 |
Application of an irreversible opiate antagonist (beta-FNA, beta-funal-trexamine) to demonstrate dynorphin selectivity for K-opioid sites.
Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Dynorphins; Electric Stimulation; Endorphins; Guinea Pigs; Morphine Derivatives; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Time Factors | 1982 |
Preparation of brain membranes containing a single type of opioid receptor highly selective for dynorphin.
Topics: Animals; Brain Chemistry; Cell Membrane; Dynorphins; Endorphins; Guinea Pigs; Ligands; Naloxone; Naltrexone; Receptors, Opioid | 1982 |
Relative involvement of mu, kappa and delta receptor mechanisms in opiate-mediated antinociception in mice.
Topics: Acetates; Acetic Acid; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Hot Temperature; Male; Mice; Naloxone; Naltrexone; Pain; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1983 |
Naltrexone metabolism and sustained release following administration of an insoluble complex to rhesus monkeys and guinea-pigs.
Topics: Animals; Biotransformation; Chromatography, Thin Layer; Delayed-Action Preparations; Female; Guinea Pigs; Hydrolysis; Macaca mulatta; Male; Naloxone; Naltrexone; Species Specificity; Time Factors | 1983 |
Comparison of dynorphin-selective Kappa receptors in mouse vas deferens and guinea pig ileum. Spare receptor fraction as a determinant of potency.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Guinea Pigs; Ileum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Structure-Activity Relationship; Vas Deferens | 1983 |
Opioid receptor selectivity of dynorphin gene products.
Topics: Animals; Dynorphins; Endorphins; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Peptide Fragments; Protein Precursors; Receptors, Opioid | 1984 |
Receptor preference of dynorphin A fragments in the mouse vas deferens determined by different techniques.
Topics: Animals; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fentanyl; Male; Mice; Naloxone; Naltrexone; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vas Deferens | 1984 |
Neurotransmitters and biphasic respiratory response to hypoxia.
Topics: Adenosine; Aminophylline; Animals; Animals, Newborn; Endorphins; Hyperventilation; Hypoxia; Naloxone; Naltrexone; Neurotransmitter Agents; Phrenic Nerve; Respiration; Swine | 1984 |
Which opioid receptor mechanism modulates feeding?
Topics: Animals; Azocines; Diprenorphine; Dynorphins; Endorphins; Feeding Behavior; Humans; Mice; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma | 1984 |
The role of opioid receptor sub-types in tifluadom-induced feeding.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Convulsants; Eating; Enkephalin, Leucine; Flumazenil; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism | 1984 |
Morphine analgesia after intrathecal administration of a narcotic agonist, chloroxymorphamine and antagonist, chlornaltrexamine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Hydromorphone; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Oxymorphone; Rats | 1980 |
Pharmacological studies with an alkylating narcotic agonist, chloroxymorphamine, and antagonist, chlornaltrexamine.
Topics: Analgesics; Animals; Brain; Hydromorphone; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nitrogen Mustard Compounds; Oxymorphone | 1980 |
Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines.
Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Drug Stability; Hydromorphone; Kinetics; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship | 1982 |
A case of episodic flushing and organic psychosis: reversal by opiate antagonists.
Topics: Adult; Anxiety Disorders; Female; Histamine Release; Humans; Mast Cells; Naloxone; Naltrexone; Neurocognitive Disorders; Pain; Skin; Vasodilator Agents | 1983 |
Quaternary opiate antagonists lower blood pressure and inhibit leucine-enkephalin responses.
Topics: Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Enkephalin, Leucine; Heart Rate; Hydromorphone; Naloxone; Naltrexone; Oxymorphone; Quaternary Ammonium Compounds | 1983 |
Diastereomeric 6-desoxy-6-spiro-alpha-methylene-gamma-butyrolactone derivatives of naltrexone and oxymorphone. Selective irreversible inhibition of naltrexone binding in an opioid receptor preparation by a conformationally restricted michael acceptor liga
Topics: Animals; Brain; Cell Membrane; Chromatography, Thin Layer; Hydromorphone; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Molecular Conformation; Naloxone; Naltrexone; Narcotic Antagonists; Optical Rotation; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship | 1984 |
Naloxone-induced increases in serum luteinizing hormone in the male: mechanisms of action.
Topics: Animals; Binding, Competitive; Castration; Dihydrotestosterone; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Luteinizing Hormone; Male; Naloxone; Naltrexone; Pituitary Gland, Anterior; Rats; Receptors, Androgen; Receptors, Opioid; Steroids | 1980 |
Selective protection of stereospecific enkephalin and opiate binding against inactivation by N-ethylmaleimide: evidence for two classes of opiate receptors.
Topics: Animals; Binding, Competitive; Brain; Endorphins; Enkephalins; Ethylmaleimide; Kinetics; Ligands; Male; Morphine; Naloxone; Naltrexone; Rats; Receptors, Opioid | 1980 |
Opiate receptors: problems of definition and characterization.
Topics: Animals; Binding Sites; Brain; Caudate Nucleus; Cyclazocine; Endorphins; Enkephalins; Hippocampus; Humans; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1980 |
The effects of opiate agonists on growth hormone and prolactin release in rats.
Topics: Animals; Apomorphine; Enkephalins; Growth Hormone; Male; Methadone; Morphine; Naloxone; Naltrexone; Parasympathomimetics; Prolactin; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Opioid; Secretory Rate | 1980 |
Electroacupuncture analgesia is mediated by stereospecific opiate receptors and is reversed by antagonists of type I receptors.
Topics: Acupuncture Therapy; Analgesia; Animals; Cyclazocine; Diprenorphine; Electric Stimulation; Female; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Stereoisomerism; Time Factors | 1980 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine | 1980 |
Influence of morphine and naltrexone on the intraocular pressure of conscious cynomolgus monkeys (Macaca fascicularis).
Topics: Animals; Drug Combinations; Intraocular Pressure; Macaca; Macaca fascicularis; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1980 |
Inhibition of growth in young mice treated with pentazocine: reversal by naltrexone.
Topics: Animals; Body Weight; Brain; Dose-Response Relationship, Drug; Growth; Liver; Mice; Muscle Proteins; Naloxone; Naltrexone; Pentazocine; Protein Biosynthesis; Receptors, Opioid | 1980 |
Opioid peptides and their receptors.
Topics: Animals; Brain; Dogs; Endorphins; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Receptors, Opioid; Vas Deferens | 1980 |
Opiate antagonists and long-term analgesic reaction induced by inescapable shock in rats.
Topics: Animals; Dose-Response Relationship, Drug; Electroshock; Humans; Naloxone; Naltrexone; Nociceptors; Rats; Reaction Time; Receptors, Opioid; Stress, Physiological | 1980 |
Isolation of selective 3H-chlornaltrexamine-bound complexes, possible opioid receptor components in brains of mice.
Topics: Animals; Brain; Chromatography, Gel; Dextrorphan; In Vitro Techniques; Mice; Naloxone; Naltrexone; Nitrogen Mustard Compounds; Receptors, Opioid | 1980 |
ACTH mediation of learned fear: blockade by naloxone and naltrexone.
Topics: Adrenocorticotropic Hormone; Animals; Avoidance Learning; Conditioning, Psychological; Drug Antagonism; Fear; Male; Naloxone; Naltrexone; Rats | 1980 |
Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists.
Topics: Animals; Brain; Columbidae; Discrimination, Psychological; Etorphine; Macaca mulatta; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid | 1981 |
The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone.
Topics: Affinity Labels; Animals; Ileum; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship | 1981 |
Chronic lithium administration alters the interaction between opiate antagonists and opiate receptors in vivo.
Topics: Animals; Behavior, Animal; Lithium; Male; Membranes; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Reaction Time; Receptors, Opioid; Time Factors | 1981 |
Different opioid systems may participate in post-electro-convulsive shock (ECS) analgesia and catalepsy.
Topics: Animals; Drug Tolerance; Electroshock; Male; Morphine; Motor Activity; Naloxone; Naltrexone; Nociceptors; Rats; Receptors, Opioid | 1981 |
Antagonism by chlornaltrexamine of some effects of delta 9-tetrahydrocannabinol in rats.
Topics: Analgesia; Animals; Dronabinol; Drug Tolerance; Humans; Hypothermia; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nitrogen Mustard Compounds; Rats; Receptors, Opioid; Substance-Related Disorders | 1981 |
Seasonal variation in the apparent number of binding sites for 3H-opioid agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Dihydromorphine; Endorphins; Enkephalin, Methionine; Enkephalins; Female; Kinetics; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Seasons | 1981 |
Characterization of the kappa-subtype of the opiate receptor in the guinea-pig brain.
Topics: Animals; Benzomorphans; Binding Sites; Binding, Competitive; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Guinea Pigs; Naloxone; Naltrexone; Narcotics; Phenoxybenzamine; Receptors, Opioid | 1981 |
Gamma-melanotropin and brain function.
Topics: Adrenocorticotropic Hormone; Animals; Behavior, Animal; beta-Endorphin; Biological Assay; Brain; Endorphins; Guinea Pigs; Melanocyte-Stimulating Hormones; Muscle Contraction; Naloxone; Naltrexone; Pituitary Hormones, Anterior; Pro-Opiomelanocortin; Protein Precursors; Rats; Receptors, Opioid | 1981 |
Irreversible inactivation of the opiate receptors in the neuroblastoma x glioma hybrid NG108-15 by chlornaltrexamine.
Topics: Animals; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Glioma; Hybrid Cells; Mice; Naloxone; Naltrexone; Neoplasms, Experimental; Neuroblastoma; Nitrogen Mustard Compounds; Prostaglandins E, Synthetic; Rats; Receptors, Opioid | 1981 |
Effects of opioid peptides on thermoregulation.
Topics: Animals; beta-Endorphin; Body Temperature Regulation; Cats; Cattle; Endorphins; Enkephalin, Methionine; Enkephalins; Mice; Naloxone; Naltrexone; Narcotics; Rats; Structure-Activity Relationship | 1981 |
Naltrexone reduces weight gain, alters "beta-endorphin", and reduces insulin output from pancreatic islets of genetically obese mice.
Topics: Animals; beta-Endorphin; Body Weight; Endorphins; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Obese; Naloxone; Naltrexone; Obesity; Pituitary Gland; Receptors, Opioid | 1980 |
ACTH-induced grooming involves high-affinity opiate receptors.
Topics: Adrenocorticotropic Hormone; Animals; Grooming; Muridae; Naloxone; Naltrexone; Receptors, Opioid | 1981 |
Effect of naltrexone on regional brain oxygen consumption in the cat.
Topics: Animals; Brain; Cats; Cerebrovascular Circulation; Female; Male; Naloxone; Naltrexone; Oxygen Consumption; Receptors, Opioid | 1982 |
Naltrexone improves survival rate and cardiovascular function in canine hemorrhagic shock.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hemodynamics; Male; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Shock, Hemorrhagic | 1982 |
Stereospecific accumulation of dihydromorphine and naltrexone by corpus striatal slices of morphine-dependent mice.
Topics: Animals; Binding, Competitive; Corpus Striatum; Dihydromorphine; Humans; In Vitro Techniques; Male; Mice; Morphine Dependence; Morphine Derivatives; Naloxone; Naltrexone; Receptors, Opioid; Stereoisomerism; Substance Withdrawal Syndrome | 1982 |
Effects of naloxone and naltrexone on locomotor activity in C57BL/6 and DBA/2 mice.
Topics: Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid; Species Specificity | 1982 |
Antagonism of morphine-induced behavioral suppression by opiate receptor alkylators.
Topics: Amphetamine; Animals; Brain; Conditioning, Operant; Exploratory Behavior; Male; Morphine; Muridae; Naloxone; Naltrexone; Nitrogen Mustard Compounds; Nociceptors; Receptors, Opioid | 1982 |
Opiate antagonists stimulate affiliative behaviour in monkeys.
Topics: Animals; Behavior, Animal; Cercopithecidae; Eating; Female; Grooming; Hydrocortisone; Luteinizing Hormone; Male; Motor Activity; Naloxone; Naltrexone; Prolactin; Receptors, Opioid; Social Behavior; Stimulation, Chemical; Sulpiride; Testosterone | 1982 |
Stimulus properties of opioids with mixed agonist and antagonist activity.
Topics: Animals; Conditioning, Psychological; Cyclazocine; Dogs; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phencyclidine; Rats; Receptors, Opioid; Saimiri | 1982 |
Interactions between narcotic agonists, partial agonists andd antagonists evaluated by punished an unpunished behavior in the rat.
Topics: Animals; Conditioning, Psychological; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenazocine; Punishment; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Pharmacological profiles of beta-funaltrexamine (beta-FNA) and beta-chlornaltrexamine (beta-CNA) on the mouse vas deferens preparation.
Topics: Animals; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Vas Deferens | 1982 |
Opiate, enkephalin, and endorphin analgesia: relations to a single subpopulation of opiate receptors.
Topics: Analgesia; Animals; Humans; Lethal Dose 50; Morphine; Muridae; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Respiration; Respiratory Insufficiency | 1981 |
Naltrexone-insensitive facilitation and naltrexone-sensitive inhibition of passive avoidance behavior of the ACTH-(4-9) analog (ORG 2766) are located in two different parts of the molecule.
Topics: Adrenocorticotropic Hormone; Animals; Avoidance Learning; Drug Interactions; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Peptide Fragments; Rats; Rats, Inbred Strains | 1982 |
Potential affinity labels for the opiate receptor based on fentanyl and related compounds.
Topics: Affinity Labels; Animals; Chemical Phenomena; Chemistry; Fentanyl; In Vitro Techniques; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Methadone-induced endorphin dysfunction in addicts.
Topics: Adrenocorticotropic Hormone; Brain; Endorphins; Humans; Hydrocortisone; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Receptors, Opioid; Substance Withdrawal Syndrome | 1982 |
Naltrexone-induced opiate receptor supersensitivity.
Topics: Animals; Brain; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Female; Guanosine Triphosphate; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Intraseptally injected opiate agents: effects on morphine-induced behaviour of cats.
Topics: Animals; Behavior, Animal; beta-Endorphin; Cats; Endorphins; Enkephalin, Methionine; Fentanyl; Morphine; Naloxone; Naltrexone; Narcotics; Receptors, Opioid; Septal Nuclei; Septum Pellucidum | 1982 |
Involvement of both adrenergic and cholinergic receptors in the cardiovascular effects of naloxone during hemorrhagic hypotension in the conscious rabbit.
Topics: Adrenergic Fibers; Animals; Atropine; Blood Pressure; Efferent Pathways; Heart Rate; Hemodynamics; Hemorrhage; Hypotension; Male; Naloxone; Naltrexone; Parasympathetic Nervous System; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Opioid | 1982 |
Extent and control of shock affects naltrexone sensitivity of stress-induced analgesia and reactivity to morphine.
Topics: Animals; Dose-Response Relationship, Drug; Electroshock; Helplessness, Learned; Humans; Male; Morphine; Naloxone; Naltrexone; Nociceptors; Rats; Receptors, Opioid; Sensory Thresholds; Stress, Physiological | 1982 |
Enhancement of osmotic- and hypovolemic-induced drinking by chlordiazepoxide in rats is blocked by naltrexone.
Topics: Animals; Chlordiazepoxide; Dose-Response Relationship, Drug; Drinking; Male; Muridae; Naloxone; Naltrexone; Polyethylene Glycols; Receptors, Opioid; Saline Solution, Hypertonic; Water-Electrolyte Balance | 1982 |
Protection of opiate receptors in NG108-15 against modification by N-ethylmaleimide.
Topics: Animals; Cell Line; Dithiothreitol; Enkephalin, Methionine; Ethylmaleimide; Glioma; Hybrid Cells; Kinetics; Mice; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid; Sulfhydryl Reagents | 1983 |
Hibernation "trigger": opioid-like inhibitory action on brain function of the monkey.
Topics: Animals; Body Temperature Regulation; Brain; Eating; Heart Rate; Hibernation; Injections, Intraventricular; Macaca mulatta; Male; Marmota; Naloxone; Naltrexone; Peptides; Proteins; Receptors, Opioid | 1982 |
Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey.
Topics: Animals; Buprenorphine; Cyclazocine; Diazepam; Diprenorphine; Drinking; Ethylketocyclazocine; Etorphine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Taste | 1982 |
Naloxone enhancement of memory processes: effects of other opiate antagonists.
Topics: Animals; Avoidance Learning; Diprenorphine; Female; Male; Memory; Mental Recall; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Retention, Psychology | 1982 |
Blockade of morphine dependence-related enhancement of secretory protein synthesis in the pons-medulla and striatum-septum by naltrexone.
Topics: Animals; Body Temperature; Body Weight; Brain; Corpus Striatum; Humans; Male; Medulla Oblongata; Morphine Dependence; Naloxone; Naltrexone; Nerve Tissue Proteins; Pons; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Determination of the relative involvement of mu-opioid receptors in opioid-induced depression of respiratory rate by use of beta-funaltrexamine.
Topics: Analgesics; Animals; Depression, Chemical; Drug Interactions; Female; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotics; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu; Respiration | 1983 |
Naltrexone-sensitive behavioral actions of the ACTH 4-9 analog (Org 2766).
Topics: Adrenocorticotropic Hormone; Animals; Avoidance Learning; Behavior, Animal; beta-Endorphin; Electric Stimulation; Endorphins; Enkephalin, Methionine; Grooming; Male; Naloxone; Naltrexone; Oligopeptides; Peptide Fragments; Rats; Rats, Inbred Strains; Self Stimulation | 1983 |
Naltrexone blocks the response-latency increasing effects but not the discriminative effects of diazepam in rats.
Topics: Animals; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Naltrexone; Rats; Rats, Inbred F344; Reaction Time; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Opiate antagonists overcome the learned helplessness effect but impair competent escape performance.
Topics: Animals; Dose-Response Relationship, Drug; Electroshock; Escape Reaction; Helplessness, Learned; Humans; Male; Muridae; Naloxone; Naltrexone; Reaction Time; Receptors, Opioid | 1983 |
Importance of C-6 chirality in conferring irreversible opioid antagonism to naltrexone-derived affinity labels.
Topics: Affinity Labels; Animals; Guinea Pigs; Ileum; Male; Mice; Naloxone; Naltrexone; Receptors, Opioid; Stereoisomerism; Vas Deferens | 1983 |
An opiate binding site in the rat brain is highly selective for 4,5-epoxymorphinans.
Topics: Animals; Brain Chemistry; Dihydromorphine; Diprenorphine; Morphine; Nalorphine; Naloxone; Naltrexone; Rats; Receptors, Opioid; Sodium; Tissue Distribution | 1983 |
Naltrexone fails to antagonize the sigma effects of PCP and SKF 10,047 in the dog.
Topics: Animals; Body Temperature; Dogs; Female; Heart Rate; Morphine; Naloxone; Naltrexone; Paraplegia; Phenazocine; Phencyclidine; Receptors, Opioid; Receptors, sigma; Reflex | 1983 |
Effect of chronic naltrexone and methadone administration on brain immunoreactive beta-endorphin in the rat.
Topics: Animals; beta-Endorphin; Brain Chemistry; Endorphins; Hypothalamus; Male; Methadone; Naloxone; Naltrexone; Radioimmunoassay; Rats; Rats, Inbred Strains | 1983 |
Morphine exacerbates anaphylactic shock in mice by stimulating central opiate receptors.
Topics: Anaphylaxis; Animals; Azocines; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1983 |
Naltrexone modulates growth in infant rats.
Topics: Animals; Animals, Newborn; Body Weight; Ear, External; Eye; Female; Growth; Hair; Male; Motor Activity; Naloxone; Naltrexone; Organ Size; Rats; Receptors, Opioid | 1983 |
Chronic naltrexone increases opiate binding in brain and produces supersensitivity to morphine in the locus coeruleus of the rat.
Topics: Animals; Brain; Etorphine; Locus Coeruleus; Male; Morphine; Naloxone; Naltrexone; Narcotics; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission; Yohimbine | 1983 |
Evidence for delta-receptor involvement in the post-ictal antinociceptive responses to electroconvulsive shock in rats.
Topics: Animals; Electroshock; Enkephalin, Leucine; Escape Reaction; Hot Temperature; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1983 |
Multiple opioid receptors: evidence for mu-delta binding site interactions in endotoxic shock.
Topics: Animals; Blood Pressure; Enkephalin, Leucine; Heart Rate; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pulse; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Shock, Septic | 1983 |
Repeated administration of naltrexone and diprenorphine decreases food intake and body weight in squirrel monkeys.
Topics: Animals; Body Weight; Diprenorphine; Dose-Response Relationship, Drug; Drinking; Eating; Female; Humans; Male; Morphinans; Naloxone; Naltrexone; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Saimiri; Salivation | 1984 |
Effect of beta-FNA on opiate receptor binding: preliminary evidence for two types of mu receptors.
Topics: Animals; Brain; In Vitro Techniques; Naloxone; Naltrexone; Oxymorphone; Rats; Receptors, Opioid; Receptors, Opioid, mu | 1983 |
ICI 154,129, a delta-opioid receptor antagonist raises seizure threshold in rats.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Seizures | 1984 |
Effects of chronic naltrexone on amphetamine locomotor activity.
Topics: Amphetamine; Animals; Drug Interactions; Male; Motor Activity; Naloxone; Naltrexone; Noise; Rats; Receptors, Opioid; Stress, Physiological | 1983 |
Affinity chromatography of solubilized opioid binding sites using CH-Sepharose modified with a new naltrexone derivative.
Topics: Animals; Bufo marinus; Cattle; Cell Membrane; Chromatography, Affinity; Corpus Striatum; Diprenorphine; Female; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sepharose | 1984 |
Naltrexone prevents footshock-induced performance deficit in rats.
Topics: Analgesia; Animals; Avoidance Learning; Electroshock; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Visualization of opiate receptor upregulation by light microscopy autoradiography.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Brain Mapping; Enkephalin, Methionine; Male; Naloxone; Naltrexone; Rats; Receptors, Opioid | 1984 |
Differential role of the opioid mu and delta receptors in the activation of prolactin (PRL) and growth hormone (GH) secretion by morphine in the male rat.
Topics: Animals; Drug Interactions; Enkephalin, Leucine; Growth Hormone; Injections, Intraventricular; Male; Morphine; Naloxone; Naltrexone; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Use of naltrexone to extinguish opioid-conditioned responses.
Topics: Adult; Combined Modality Therapy; Conditioning, Classical; Extinction, Psychological; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Recurrence; Relaxation Therapy | 1984 |
Narcotic discrimination in pigeons: antagonism by naltrexone.
Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Meperidine; Morphine; Naloxone; Naltrexone; Narcotics | 1984 |
Effects of naloxone and naltrexone on the increased water intake and drinking duration in phenobarbitone-treated rats.
Topics: Animals; Drinking Behavior; Drug Synergism; Male; Naloxone; Naltrexone; Phenobarbital; Rats; Time Factors | 1983 |
Antagonism of the behavioral effects of ethanol by naltrexone in BALB/c, C57BL/6, and DBA/2 mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Naloxone; Naltrexone | 1983 |
Predictors of favorable outcome following naltrexone treatment.
Topics: Employment; Humans; Morphine; Naloxone; Naltrexone; Opioid-Related Disorders; Time Factors | 1983 |
Facilitation of hot-plate response learning by pre- and posttraining naltrexone administration.
Topics: Animals; Learning; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Reaction Time | 1983 |
Pharmacokinetic quantitation of naltrexone controlled release from a copolymer delivery system.
Topics: Animals; Delayed-Action Preparations; Female; Haplorhini; Kinetics; Male; Naloxone; Naltrexone | 1983 |
Effects of opiate antagonists on hormones and behavior of male and female rhesus monkeys.
Topics: Aggression; Animals; Castration; Female; Follicle Stimulating Hormone; Hydrocortisone; Luteinizing Hormone; Macaca mulatta; Male; Naloxone; Naltrexone; Sexual Behavior, Animal; Social Environment; Testosterone | 1984 |
Modifications in food intake and energy metabolism in rats as a function of chronic naltrexone infusions.
Topics: Adipose Tissue; Animals; Body Temperature; Body Weight; Carbon Dioxide; Drinking Behavior; Energy Metabolism; Feeding Behavior; Infusions, Parenteral; Male; Naloxone; Naltrexone; Oxygen Consumption; Rats; Rats, Inbred Strains | 1984 |
Abstinence treatments for opiate addicts: therapeutic community or naltrexone?
Topics: Follow-Up Studies; Humans; Male; Naloxone; Naltrexone; Opioid-Related Disorders; Substance-Related Disorders; Therapeutic Community | 1984 |
Five-year follow-up of opiate addicts with naltrexone and behavior therapy.
Topics: Adult; Behavior Therapy; Combined Modality Therapy; Follow-Up Studies; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Recurrence | 1984 |
Naloxone and naltrexone block the gastrointestinal effects of TRH and MK-212.
Topics: Animals; Digestive System; Male; Naloxone; Naltrexone; Pyrazines; Rabbits; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1984 |
[Opiate antagonists].
Topics: Endorphins; Humans; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Thyrotropin-Releasing Hormone | 1984 |
Acute effects of naloxone and naltrexone, but lack of delayed effects, on exploratory behavior in the rat.
Topics: Animals; Exploratory Behavior; Male; Motor Activity; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Physiologic and morphologic changes and incidence of neoplasms in mice and rats fed naltrexone HCl for 24 months.
Topics: Administration, Oral; Animals; Behavior, Animal; Carcinogens; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eating; Female; Growth; Lethal Dose 50; Male; Mice; Naloxone; Naltrexone; Neoplasms, Experimental; Rats; Rats, Inbred F344; Sex Factors; Species Specificity | 1984 |
Bioequivalence, dose-proportionality, and pharmacokinetics of naltrexone after oral administration.
Topics: Administration, Oral; Adult; Dosage Forms; Dose-Response Relationship, Drug; Half-Life; Humans; Kinetics; Male; Naloxone; Naltrexone; Nausea; Tablets; Therapeutic Equivalency | 1984 |
Naltrexone: a clinical perspective.
Topics: Adult; Alcohol Drinking; Ambulatory Care; Follow-Up Studies; Heroin Dependence; Hospitalization; Humans; Middle Aged; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Dropouts; Social Support; Substance Withdrawal Syndrome | 1984 |
Naltrexone induction: psychologic and pharmacologic strategies.
Topics: Ambulatory Care; Behavior Therapy; Clonidine; Counseling; Drug Administration Schedule; Drug Therapy, Combination; Family Therapy; Hospitalization; Humans; Illicit Drugs; Injections, Intramuscular; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Dropouts; Research Design | 1984 |
Clinical experience with naltrexone in suburban opioid addicts.
Topics: Adult; Ambulatory Care; Combined Modality Therapy; Female; Guanabenz; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Dropouts; Psychotherapy; Suburban Population; Time Factors | 1984 |
Naltrexone treatment for addicted health-care professionals: a collaborative private practice experience.
Topics: Adult; Age Factors; Aged; Female; Health Occupations; Humans; Male; Middle Aged; Naloxone; Naltrexone; Opioid-Related Disorders; Outcome and Process Assessment, Health Care; Physician Impairment; Private Practice; Time Factors | 1984 |
Naltrexone treatment in a jail work-release program.
Topics: Adolescent; Adult; Ambulatory Care; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; New York; Opioid-Related Disorders; Outcome and Process Assessment, Health Care; Prisoners; Psychological Tests; Psychotherapy | 1984 |
Reproductive toxicity and teratology evaluations of naltrexone.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estrus; Female; Fertility; Fetus; Humans; Male; Maternal-Fetal Exchange; Naloxone; Naltrexone; Pregnancy; Rabbits; Rats; Reproduction; Sex Factors; Sexual Behavior, Animal; Teratogens | 1984 |
The index of choice: indications of methadone patients' selection of naltrexone treatment.
Topics: Adult; Attitude; Humans; Internal-External Control; Male; Methadone; Motivation; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Acceptance of Health Care; Prospective Studies; Self Concept; Social Environment | 1984 |
Strategies to improve compliance with narcotic antagonists.
Topics: Combined Modality Therapy; Humans; Life Style; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Compliance; Patient Dropouts; Research; Social Support; Substance Withdrawal Syndrome | 1984 |
Naltrexone treatment of heroin addiction: one-year follow-up.
Topics: Adult; Age Factors; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadyl Acetate; Motivation; Naloxone; Naltrexone | 1984 |
Ventromedial and lateral hypothalamic injections of naloxone or naltrexone suppress the acute food intake of food-deprived rats.
Topics: Animals; Anorexia; Eating; Food Deprivation; Hypothalamic Area, Lateral; Injections; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Ventromedial Hypothalamic Nucleus | 1984 |
Kinetics of a naltrexone sustained-release preparation.
Topics: Absorption; Adult; Biological Availability; Delayed-Action Preparations; Drug Implants; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Naloxone; Naltrexone | 1984 |
Naltrexone-reversible effects of flunitrazepam on locomotor activity and passive avoidance behaviour in mice.
Topics: Animals; Avoidance Learning; Flunitrazepam; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Naloxone; Naltrexone | 1984 |
Naloxone protein binding in adult and foetal plasma.
Topics: Adult; Blood Proteins; Female; Fetal Blood; Humans; Male; Naloxone; Naltrexone; Pregnancy; Protein Binding; Serum Albumin | 1984 |
Nalmefene: radioimmunoassay for a new opioid antagonist.
Topics: Humans; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Radioimmunoassay | 1984 |
Methadone and naltrexone in the treatment of heroin dependence.
Topics: Heroin Dependence; Humans; Methadone; Naloxone; Naltrexone; Psychotherapy; Substance Withdrawal Syndrome; Time Factors | 1984 |
Effects of centrally administered naloxone on phrenic nerve activity.
Topics: Animals; Cats; Central Nervous System; Endorphins; Injections, Intravenous; Injections, Intraventricular; Naloxone; Naltrexone; Phrenic Nerve; Respiration | 1984 |
Effects of naltrexone on plasma corticosterone in opiate-naive rats: a central action.
Topics: Animals; Corticosterone; Dose-Response Relationship, Drug; Humans; Hypothalamo-Hypophyseal System; Male; Morphine Dependence; Naloxone; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Inbred Strains | 1984 |
A rapid, quantitative in vivo assay for narcotic antagonists.
Topics: Animals; Dose-Response Relationship, Drug; Female; Humans; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Skin Temperature; Tail; Time Factors | 1984 |
Do testicular opiates regulate Leydig cell function?
Topics: Androgen-Binding Protein; Animals; Chorionic Gonadotropin; Endorphins; Epididymis; Leydig Cells; Male; Naloxone; Naltrexone; Organ Size; Rats; Rats, Inbred Strains; Testosterone | 1984 |
Endogenous opiates and stress. Behavioral activation elicited in the rat and effects of naltrexone, diprenorphine and morphine.
Topics: Animals; Behavior, Animal; Diprenorphine; Endorphins; Humans; Male; Morphinans; Morphine; Naloxone; Naltrexone; Noise; Rats; Rats, Inbred Strains; Receptors, Drug; Stress, Psychological; Time Factors | 1984 |
The behavioural depression of hippocampal kindled rats is attenuated by subcutaneous and intracerebroventricular naltrexone.
Topics: Amygdala; Animals; Depression; Humans; Injections, Intraventricular; Injections, Subcutaneous; Kindling, Neurologic; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1984 |
Opioid involvement in hypertension induced by short-term isolation.
Topics: Adrenalectomy; Animals; Clonidine; Endorphins; Humans; Hypertension; Male; Naloxone; Naltrexone; Psychophysiologic Disorders; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Social Isolation | 1984 |
The effects of intrathecal morphine and naltrexone on autotomy in sciatic nerve sectioned rats.
Topics: Animals; Behavior, Animal; Differential Threshold; Disease Models, Animal; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Nociceptors; Pain; Rats; Rats, Inbred Strains; Sciatic Nerve; Time Factors | 1984 |
Endorphins in endotoxin-induced hyperglycemia in mice.
Topics: Animals; Endorphins; Endotoxins; Hyperglycemia; Male; Mice; Mice, Inbred C3H; Morphine; Naloxone; Naltrexone; Quaternary Ammonium Compounds | 1983 |
Neurohormonal modulation of natural resistance to a murine lymphoma.
Topics: Animals; Corticosterone; Electroshock; Handling, Psychological; Hydrocortisone; Immunity, Innate; Lymphoma; Mice; Mice, Inbred DBA; Naloxone; Naltrexone | 1984 |
Increased brain size and cellular content in infant rats treated with an opiate antagonist.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Cerebellum; Morphine; Naloxone; Naltrexone; Neuroglia; Organ Size; Rats; Rats, Inbred Strains; Somatosensory Cortex | 1983 |
Role of endorphins in endotoxin-induced hyperglycaemia in mice.
Topics: Animals; Blood Glucose; Drug Tolerance; Endorphins; Endotoxins; Hyperglycemia; Male; Mice; Mice, Inbred C3H; Morphine; Naloxone; Naltrexone | 1983 |
Nalmefene decreases meal size, food and water intake and weight gain in Zucker rats.
Topics: Animals; Appetite; Appetite Depressants; Body Weight; Drinking; Energy Intake; Female; Male; Naloxone; Naltrexone; Obesity; Rats; Rats, Zucker; Time Factors | 1983 |
Opiate antagonists, morphine and spatial memory in rats.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Male; Memory; Morphine; Naloxone; Naltrexone; Rats; Retention, Psychology | 1983 |
Patterns of drinking in the rat following the administration of opiate antagonists.
Topics: Animals; Depression, Chemical; Diprenorphine; Drinking Behavior; Male; Morphinans; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Water Deprivation | 1983 |
Naltrexone and clonidine: alternatives to methadone.
Topics: Clonidine; Humans; Naloxone; Naltrexone; Opioid-Related Disorders | 1983 |
Interaction of the opiate antagonist, naltrexone methyl bromide, with the acetylcholine receptor system of the motor end-plate.
Topics: Animals; Female; Membrane Potentials; Motor Endplate; Naloxone; Naltrexone; Neuromuscular Junction; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1983 |
Opioid antagonists inhibit the growth of metastatic murine neuroblastoma.
Topics: Animals; Cell Line; Male; Mice; Naloxone; Naltrexone; Neoplasm Transplantation; Neuroblastoma; Probability; Time Factors | 1983 |
Morphine antagonizes pentobarbital-induced anesthesia.
Topics: Anesthesia; Animals; Atropine; Behavior, Animal; Electroencephalography; Male; Morphine; Naloxone; Naltrexone; Pentobarbital; Rabbits; Seizures | 1983 |
Predictors of favorable outcome following naltrexone treatment.
Topics: Employment; Follow-Up Studies; Humans; Male; Marriage; Naloxone; Naltrexone; Opioid-Related Disorders; Patient Acceptance of Health Care; Regression Analysis; Social Support; Time Factors | 1983 |
Inhibition of morphine-induced analgesia and locomotor activity in strains of mice: a comparison of long-acting opiate antagonists.
Topics: Animals; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Motor Activity; Naloxone; Naltrexone; Pain; Species Specificity | 1983 |
Nalmefene: quantitation of a new narcotic antagonist in human plasma using high performance-liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Kinetics; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Time Factors | 1983 |
Determination of naloxone in blood by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infant, Premature; Naloxone; Naltrexone | 1983 |
Discriminative stimulus effects of naltrexone in narcotic-naive and morphine-treated pigeons.
Topics: Animals; Columbidae; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Humans; Morphine Dependence; Naloxone; Naltrexone | 1983 |
Prolonged excretion of morphine in rats during protracted abstinence: lack of effect of naltrexone.
Topics: Animals; Body Weight; Gas Chromatography-Mass Spectrometry; Humans; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1983 |
A preliminary description of acute physical dependence on morphine in the vervet monkey.
Topics: Animals; Behavior, Animal; Catheterization; Chlorocebus aethiops; Humans; Male; Morphine; Morphine Dependence; Naloxone; Naltrexone; Substance Withdrawal Syndrome | 1983 |
Reversal of morphine-induced catalepsy in the rat by narcotic antagonists and their quaternary derivatives.
Topics: Animals; Catalepsy; Humans; Injections, Intraventricular; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains | 1983 |
Use of the novel irreversible opiate antagonist, beta-chlornaltrexamine, in the estimation of the normorphine affinity constant in naive and morphine tolerant guinea-pig ilea.
Topics: Animals; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists | 1983 |
Spinal antagonism of tolerance and dependence induced by systemically administered morphine.
Topics: Animals; Drug Tolerance; Humans; Male; Morphine; Morphine Dependence; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Reaction Time; Spinal Cord | 1983 |
Effect of naltrexone on food intake and hoarding in white-footed mice (Peromyscus).
Topics: Animals; Eating; Feeding Behavior; Female; Injections, Intraperitoneal; Male; Naloxone; Naltrexone; Peromyscus | 1984 |
Opiate antagonists reverse the hypoactivity associated with systemic anaphylaxis in mice.
Topics: Anaphylaxis; Animals; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists | 1984 |
Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Heroin; Male; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Administration; Time Factors | 1984 |
Pharmacological profile of wet-dog shaking induced by electrical stimulation of the fornix in rats.
Topics: Adenosine; Aminooxyacetic Acid; Animals; Atropine; Behavior, Animal; Dopamine; Electric Stimulation; Electrodes, Implanted; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Limbic System; Naloxone; Naltrexone; Neural Pathways; Physostigmine; Picrotoxin; Propranolol; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Naloxone improves, and morphine exacerbates, experimental shock induced by release of endogenous histamine by compound 48/80.
Topics: Animals; Central Nervous System; Endorphins; Histamine; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; p-Methoxy-N-methylphenethylamine; Shock | 1984 |
Electrochemical chromatographic determinations of morphine antagonists in biological fluids, with applications.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Erythrocytes; Humans; In Vitro Techniques; Morphine; Naloxone; Naltrexone; Protein Binding; Ultracentrifugation | 1984 |
Naltrexone effects on pituitary neurointermediate lobe and median eminence.
Topics: Animals; Axons; Cytoplasm; Dose-Response Relationship, Drug; Ependyma; Male; Median Eminence; Microscopy, Electron; Naloxone; Naltrexone; Norepinephrine; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains | 1984 |
Effects of naloxone and naltrexone on drug-induced hypothermia in mice.
Topics: Animals; Apomorphine; Body Temperature; Body Temperature Regulation; Dopamine; Haloperidol; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotics; Pentobarbital | 1984 |
Ethanol inhibits the naloxone-induced release of luteinizing hormone-releasing hormone from the hypothalamus of the male rat.
Topics: Animals; Cell Membrane; Dose-Response Relationship, Drug; Drug Antagonism; Ethanol; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Male; Naloxone; Naltrexone; Pituitary Gland; Rats; Rats, Inbred Strains | 1982 |
Alteration of ethanol self-administration by naltrexone.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Haplorhini; Macaca mulatta; Male; Naloxone; Naltrexone; Reinforcement, Psychology; Self Administration | 1980 |
Clonidine hydrochloride detoxification from methadone treatments: the value of naltrexone aftercare.
Topics: Adolescent; Clonidine; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Opium; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1981 |
Psychotherapy and naltrexone in opioid dependence.
Topics: Adult; Humans; Naloxone; Naltrexone; Opioid-Related Disorders; Opium; Psychotherapy; Time Factors | 1981 |
Narcotic antagonists: naltrexone pharmacochemistry and sustained-release preparations.
Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Humans; Naloxone; Naltrexone; Narcotic Antagonists | 1981 |
The metabolism of naltrexone in man.
Topics: Administration, Oral; Biotransformation; Erythrocytes; Feces; Humans; Injections, Intravenous; Injections, Subcutaneous; Naloxone; Naltrexone | 1981 |
The clinical pharmacology of naltrexone: pharmacology and pharmacodynamics.
Topics: Animals; Biotransformation; Feces; Humans; Naloxone; Naltrexone; Opioid-Related Disorders; Time Factors; Tissue Distribution | 1981 |
Overview of human pharmacokinetics of naltrexone.
Topics: Humans; Kinetics; Male; Naloxone; Naltrexone | 1981 |
Pharmacokinetic quantitation of naltrexone release from several sustained-release delivery systems.
Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Haplorhini; Humans; Injections; Injections, Subcutaneous; Kinetics; Naloxone; Naltrexone | 1981 |
An electron-capture gas chromatographic assay for naltrexone in biological fluids.
Topics: Chromatography, Gas; Humans; Naloxone; Naltrexone | 1981 |
Solid solutions as long-acting naltrexone delivery systems.
Topics: Analgesics; Animals; Chemistry, Pharmaceutical; Drug Implants; Naloxone; Naltrexone; Rats; Solubility | 1981 |
Historical perspective on the chemistry and development of naltrexone.
Topics: Animals; Benzomorphans; Heroin Dependence; History, 20th Century; Humans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists | 1981 |
Quantitative determination of naltrexone, 6 beta-naltrexol and 2-hydroxy-3-methoxy-6 beta-naltrexol (HMN) in human plasma, red blood cells, saliva and urine by gas liquid chromatography.
Topics: Biotransformation; Chromatography, Gas; Erythrocytes; Humans; Hydrolysis; Naloxone; Naltrexone; Saliva | 1981 |
Analytical methods for quantitative and qualitative analysis of naltrexone and metabolites in biological fluids.
Topics: Body Fluids; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Naloxone; Naltrexone | 1981 |
A comparative study of the oral, intravenous, and subcutaneous administration of 3H-naltrexone to normal male volunteers.
Topics: Administration, Oral; Feces; Humans; Injections, Intravenous; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Time Factors | 1981 |
Threshold differences for naloxone and naltrexone in the hypothalamus and midbrain using fixed ratio brain self-stimulation in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Electrodes, Implanted; Hypothalamus; Male; Mesencephalon; Morphine; Naloxone; Naltrexone; Rats; Reinforcement Schedule; Self Stimulation | 1981 |
Effects of selected opioid agonists and antagonists on DMT- and LSD-25-induced disruption of food-rewarded bar pressing behavior in the rat.
Topics: Animals; Conditioning, Operant; Drug Interactions; Drug Synergism; Lysergic Acid Diethylamide; Male; Methadone; Morphine; N,N-Dimethyltryptamine; Naloxone; Naltrexone; Narcotics; Rats; Reinforcement, Psychology; Tryptamines | 1981 |
Naltrexone and psychotherapy.
Topics: Heroin Dependence; Humans; Naloxone; Naltrexone; Psychotherapy | 1982 |
Cardiovascular effects of naloxone, naltrexone and morphine in the squirrel monkey.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Male; Morphine; Naloxone; Naltrexone; Saimiri | 1983 |
Stereospecific enhancement of evoked release of brain acetylcholine by narcotic antagonists.
Topics: Acetylcholine; Animals; Brain; Electric Stimulation; Enkephalins; Hypophysectomy; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Stereoisomerism | 1983 |
Attenuation of alcohol drinking in tetrahydroisoquinoline-treated rats by morphine and naltrexone.
Topics: Alcohol Drinking; Animals; Body Weight; Drinking Behavior; Feeding Behavior; Isoquinolines; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines | 1983 |
Effects of naloxone and its quarternary analogue on stimulation-induced feeding.
Topics: Animals; Electric Stimulation; Feeding Behavior; Hypothalamus; Male; Naloxone; Naltrexone; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains | 1983 |
Effects of opiate agonists and antagonists on fluid intake and saccharin choice in the rat.
Topics: Animals; Choice Behavior; Drinking Behavior; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Saccharin | 1983 |
Effects of chronic antenatal and postnatal administration of narcotics on naloxone-induced anorexia in preweanling rats.
Topics: Aging; Animals; Animals, Suckling; Body Weight; Drug Interactions; Feeding Behavior; Female; Motor Activity; Naloxone; Naltrexone; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1983 |
Naltrexone modulates tumor response in mice with neuroblastoma.
Topics: Animals; Dose-Response Relationship, Drug; Endorphins; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Neoplasm Transplantation; Neoplasms, Experimental; Neuroblastoma | 1983 |
Naltrexone effects on plasma vasopressin concentration elevated and lowered by various stimuli.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Hematocrit; Male; Naloxone; Naltrexone; Nicotine; Rats; Rats, Inbred Strains; Sodium; Stress, Physiological; Water-Electrolyte Balance | 1983 |
Effects of opiate antagonists on social and aggressive behavior of isolated mice.
Topics: Aggression; Analysis of Variance; Animals; Humans; Male; Mice; Mice, Inbred DBA; Naloxone; Naltrexone; Social Behavior; Social Isolation | 1982 |
Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Cyclazocine; Discrimination, Psychological; Ethylketocyclazocine; Humans; Macaca; Macaca mulatta; Morphine; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Reinforcement, Psychology; Self Administration | 1982 |
Drinking, but not feeding, is opiate-sensitive in hamsters.
Topics: Animals; Anorexia; Cricetinae; Deoxyglucose; Dexamethasone; Drinking; Eating; Feeding Behavior; Food Deprivation; Insulin; Male; Mesocricetus; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1982 |
Opiate antagonists stimulate ruminal motility of conscious goats.
Topics: Animals; Female; Goats; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Rumen | 1982 |
Effect of endogenous opioid blockade on the amplitude and frequency of pulsatile luteinizing hormone secretion in normal men.
Topics: Adult; Endorphins; Humans; Luteinizing Hormone; Male; Naloxone; Naltrexone | 1982 |
Opiates and thermoregulation in mice. II. Effects of opiate antagonists.
Topics: Animals; Body Temperature Regulation; Dose-Response Relationship, Drug; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Time Factors | 1982 |
Opiate modification of amygdaloid-kindled seizures in rats.
Topics: Amygdala; Animals; Electroencephalography; Kindling, Neurologic; Male; Morphine; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains | 1982 |
Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites.
Topics: Animals; Chemical Phenomena; Chemistry; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Ligands; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists | 1982 |
Quaternary narcotic antagonists' relative ability to prevent antinociception and gastrointestinal transit inhibition in morphine-treated rats as an index of peripheral selectivity.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Gastrointestinal Motility; Male; Morphine; Nalorphine; Naloxone; Naltrexone; Pain; Rats; Structure-Activity Relationship | 1982 |
Effects of yohimbine and naltrexone in counteraction of the morphine Straub tail and the amphetamine-potentiated morphine Straub tail in mice.
Topics: Amphetamine; Animals; Male; Mice; Morphine; Naloxone; Naltrexone; Phentolamine; Tail; Yohimbine | 1982 |
A comparison of the effects of opiate antagonists on operant and ingestive behavior.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking; Eating; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1982 |
The effects of chronic administration of naltrexone on appetite and water exchange in rats.
Topics: Animals; Appetite; Drinking; Eating; Kidney Concentrating Ability; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Water-Electrolyte Balance | 1982 |
Development of tolerance to the effects of morphine on luteinizing hormone secretion as a function of castration in the male rat.
Topics: Analgesics; Animals; Brain; Castration; Dose-Response Relationship, Drug; Drug Tolerance; Luteinizing Hormone; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Testosterone | 1982 |
Effects of opiate antagonists and of morphine on chlordiazepoxide-induced hyperdipsia in the water-deprived rat.
Topics: Analysis of Variance; Animals; Chlordiazepoxide; Drinking; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Thirst; Water Deprivation | 1982 |
Analysis of the interaction of naltrexone with eating following adrenergic and cholinergic stimulation of the hypothalamus.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Feeding Behavior; Hypothalamus; Male; Naloxone; Naltrexone; Norepinephrine; Rats; Rats, Inbred Strains | 1982 |
Data acquisition system used in studying naltrexone and behavior of primates.
Topics: Animals; Computers; Data Collection; Female; Macaca radiata; Methods; Motor Activity; Naloxone; Naltrexone; Social Behavior | 1982 |
Potentiation by naltrexone of d-amphetamine-induced behavioral suppression and its reversal by clonidine.
Topics: Animals; Clonidine; Conditioning, Operant; Dextroamphetamine; Drug Interactions; Male; Naloxone; Naltrexone; Pimozide; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1982 |
Palatability-induced drinking after administration of morphine, naltrexone and diazepam in the non-deprived rat.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drinking; Male; Morphine; Muridae; Naloxone; Naltrexone; Taste | 1982 |
Chronic administration of naltrexone alters central catecholamine levels but not the development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain Chemistry; Catecholamines; Heart Rate; Hypertension; Male; Naloxone; Naltrexone; Norepinephrine; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Narcotic antagonist potentiation of L-DOPA in the reversal of reserpine induced catalepsy.
Topics: Animals; Catalepsy; Drug Synergism; Humans; Levodopa; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Reserpine; Time Factors | 1980 |
Naloxone overcomes the dopaminergic, EEG, and behavioral effects of gamma-hydroxybutyrate.
Topics: 4-Butyrolactone; Animals; Behavior, Animal; Catalepsy; Corpus Striatum; Dopamine; Electroencephalography; Epinephrine; Furans; Humans; Male; Naloxone; Naltrexone; Rats | 1980 |
Behavioural and endocrine effects of naltrexone in male talapoin monkeys.
Topics: Aggression; Animals; Cercopithecidae; Hormones; Humans; Male; Naloxone; Naltrexone; Sexual Behavior, Animal; Social Behavior | 1980 |
The relationship between the acute behavioral effects of narcotic antagonists and the narcotic-dependent state [proceedings].
Topics: Animals; Behavior, Animal; Columbidae; Cyclazocine; Humans; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists | 1981 |
Effects of narcotic antagonists on L-dopa reversal of reserpine-induced catalepsy and blepharoptosis in mice.
Topics: Animals; Blepharoptosis; Catalepsy; Drug Antagonism; Drug Synergism; Humans; Kinetics; Levodopa; Male; Mice; Naloxone; Naltrexone; Reserpine | 1981 |
Naltrexone effects on morphine and food self-administration in morphine-dependent rhesus monkeys.
Topics: Animals; Conditioning, Operant; Food; Humans; Macaca mulatta; Male; Morphine; Morphine Dependence; Naloxone; Naltrexone; Self Administration; Substance Withdrawal Syndrome | 1981 |
Antagonism of gut, but not central effects of morphine with quaternary narcotic antagonists.
Topics: Animals; Central Nervous System; Diarrhea; Digestive System; Dogs; Female; Humans; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Rats; Rats, Inbred Strains; Species Specificity; Substance Withdrawal Syndrome | 1982 |
Tetrahydroisoquinoline and opioid substrates of alcohol actions.
Topics: Alcoholism; Animals; Disease Models, Animal; Ethanol; Humans; Isoquinolines; Macaca mulatta; Male; Naloxone; Naltrexone; Narcotics; Rats; Rats, Inbred Strains; Self Administration; Tetrahydroisoquinolines | 1982 |
Lack of effect of choline and narcotic antagonists upon apomorphine discrimination.
Topics: Animals; Apomorphine; Choline; Discrimination Learning; Haloperidol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Dopamine | 1980 |
Reduced behavioral activity due to opiate blockade: relations to stress.
Topics: Animals; Endorphins; Male; Motor Activity; Naloxone; Naltrexone; Rats; Stress, Physiological; Time Factors | 1981 |
Acute and chronic effects of naltrexone and naloxone on schedule-controlled behavior of squirrel monkeys and pigeons.
Topics: Animals; Behavior, Animal; Columbidae; Conditioning, Psychological; Dose-Response Relationship, Drug; Food; Male; Morphine; Naloxone; Naltrexone; Saimiri; Time Factors | 1981 |
Effects of naltrexone dose and history of naltrexone exposure on food- and codeine-maintained responding in rhesus monkeys.
Topics: Animals; Codeine; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Macaca mulatta; Naloxone; Naltrexone; Reaction Time | 1981 |
Suppression of drinking by naloxone in the rat: a further characterization.
Topics: Angiotensin II; Animals; Depression, Chemical; Drinking; Isoproterenol; Male; Naloxone; Naltrexone; Rats; Reinforcement Schedule | 1981 |
Opiate regulation of angiotensin-induced drinking and vasopressin release.
Topics: Angiotensin II; Animals; Drinking; Endorphins; Enkephalin, Leucine; Enkephalins; Male; Naloxone; Naltrexone; Rats; Saralasin; Vasopressins | 1981 |
Narcotic antagonists attenuate drinking induced by water deprivation in a primate.
Topics: Animals; Diprenorphine; Dose-Response Relationship, Drug; Drinking Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saimiri; Water Deprivation | 1981 |
Supersensitivity to the behavioral effects of opiate antagonists [proceedings].
Topics: Animals; Behavior, Animal; Guinea Pigs; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saimiri | 1981 |
Enhancement of apomorphine-induced climbing in mice by reversible and irreversible narcotic antagonist drugs.
Topics: Animals; Apomorphine; Behavior, Animal; Drug Synergism; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nitrogen Mustard Compounds; Time Factors | 1981 |
Naltrexone-induced LH release in ovariectomized estrogen-primed rats.
Topics: Afferent Pathways; Animals; Castration; Dose-Response Relationship, Drug; Estrogens; Female; Hypothalamus; Luteinizing Hormone; Naloxone; Naltrexone; Rats | 1981 |
Opiate antagonists: central sites of action in suppressing water intake of the rat.
Topics: Animals; Dose-Response Relationship, Drug; Drinking Behavior; Male; Naloxone; Naltrexone; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains | 1981 |
The anorexic effect of naltrexone is independent of its suppressant effect on water intake.
Topics: Animals; Appetite Depressants; Drinking; Food Deprivation; Male; Naloxone; Naltrexone; Rats; Water Deprivation | 1981 |
Suppression of drinking by naloxone in rats homo- and heterozygous for diabetes insipidus.
Topics: Animals; Diabetes Insipidus; Drinking Behavior; Heterozygote; Homozygote; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Naltrexone suppresses hyperphagia induced in the rat by a highly palatable diet.
Topics: Animals; Benzamides; DEET; Feeding Behavior; Male; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Taste | 1981 |
Blockade by naltrexone of analgesia produced by stimulation of the dorsal raphe nucleus.
Topics: Analgesia; Animals; Brain Stem; Dose-Response Relationship, Drug; Electric Stimulation; Male; Naloxone; Naltrexone; Raphe Nuclei; Rats; Rats, Inbred Strains | 1981 |
Effects of chronic administration of naltrexone on appetitive behaviors of rats.
Topics: Analgesia; Animals; Appetitive Behavior; Body Weight; Drinking Behavior; Food Deprivation; Kinetics; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1981 |
Naltrexone and the tail flick reflex.
Topics: Analgesics; Animals; Drug Interactions; Drug Tolerance; Male; Morphine; Naloxone; Naltrexone; Nociceptors; Rats; Rats, Inbred Strains; Reflex | 1981 |
Multiple family therapy and naltrexone in the treatment of opiate dependence.
Topics: Adolescent; Adult; Data Collection; Family Therapy; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotics; Retrospective Studies; Statistics as Topic; Substance-Related Disorders | 1981 |
Naltrexone effects on food-and codeine-maintained responding in rhesus monkeys.
Topics: Animals; Behavior, Animal; Codeine; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Macaca mulatta; Naloxone; Naltrexone; Reinforcement, Psychology; Self Administration | 1981 |
Naltrexone partially inhibits the estrogen-induced increase in prolactin secretion and anterior pituitary weight.
Topics: Animals; Castration; Estradiol; Female; Male; Naloxone; Naltrexone; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains | 1981 |
Naltrexone: a short-term treatment for opiate dependence.
Topics: Adult; Employment; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Opioid-Related Disorders; Outcome and Process Assessment, Health Care; Patient Dropouts; Substance Withdrawal Syndrome; Time Factors | 1981 |
The naloxone test for opiate dependence.
Topics: Humans; Injections, Intramuscular; Injections, Intravenous; Methadyl Acetate; Naloxone; Naltrexone; Narcotics; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1980 |
The seminal excretion, plasma elimination, tissue distribution and metabolism of naltrexone in the rabbit.
Topics: Animals; Biotransformation; Countercurrent Distribution; Gas Chromatography-Mass Spectrometry; Half-Life; Injections, Intravenous; Kinetics; Male; Naloxone; Naltrexone; Rabbits; Semen; Tissue Distribution | 1980 |
Effects of heroin and naltrexone on plasma prolactin levels in man.
Topics: Adult; Heroin; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Prolactin | 1980 |
Self-administration of D-Ala2-Met-enkephalinamide at hypothalamic self-stimulation sites.
Topics: Animals; Dextrorphan; Dose-Response Relationship, Drug; Electric Stimulation; Endorphins; Enkephalins; Hypothalamus; Levallorphan; Levorphanol; Male; Morphine; Naloxone; Naltrexone; Rats; Self Stimulation | 1980 |
Naltrexone influence on hibernation.
Topics: Acclimatization; Animals; Hibernation; Naloxone; Naltrexone; Rodentia; Sleep | 1980 |
Heroin and naltrexone effects on pituitary-gonadal hormones in man: interaction of steroid feedback effects, tolerance and supersensitivity.
Topics: Adult; Drug Tolerance; Feedback; Heroin Dependence; Humans; Luteinizing Hormone; Male; Naloxone; Naltrexone; Testosterone; Time Factors | 1980 |
Interactions between naltrexone and non-opiate drugs evaluated by schedule-controlled behavior.
Topics: Animals; Conditioning, Operant; Dopamine; Drug Interactions; Ethanol; Male; Naloxone; Naltrexone; Rats; Reinforcement Schedule | 1980 |
The treatment of heroin addiction: naltrexone alone and with behavior therapy.
Topics: Adult; Behavior Therapy; Extinction, Psychological; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Outcome and Process Assessment, Health Care; Patient Dropouts | 1980 |
Repeated administration of naltrexone produces tolerance to naloxone-induced hyperalgesia.
Topics: Animals; Drug Tolerance; Male; Mice; Naloxone; Naltrexone; Pain | 1980 |
The effects of opiate antagonists on the discriminative stimulus properties of ethanol.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Generalization, Psychological; Male; Naloxone; Naltrexone; Narcotic Antagonists; Prejudice; Rats | 1981 |
Orally administered opioid antagonists reverse both mu and kappa opioid agonist delay of gastrointestinal transit in the guinea pig.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Gastrointestinal Transit; Guinea Pigs; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Characterization of the opioid receptor subtypes mediating the negative inotropic effects of DAMGO, DPDPE and U-50, 488H in isolated human right atria strips.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Aged; Analgesics; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Heart Atria; Humans; Male; Middle Aged; Myocardial Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Receptors, Opioid | 1995 |
Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment.
Topics: Analgesia; Analgesics, Opioid; Animals; Behavior, Animal; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Electrophysiology; Ganglia, Spinal; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Pain Measurement; Substance Withdrawal Syndrome; Substance-Related Disorders | 1995 |
The in vitro pharmacological characterization of naloxone benzoylhydrazone.
Topics: Animals; Benzeneacetamides; Binding, Competitive; Computer Simulation; Cyclohexanes; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Myenteric Plexus; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Activity at phencyclidine and mu opioid sites mediates the hyperalgesic and antinociceptive properties of the N-terminus of substance P in a model of visceral pain.
Topics: Animals; Biological Assay; Disease Models, Animal; Dizocilpine Maleate; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peptide Fragments; Phencyclidine; Receptors, Opioid, mu; Spinal Cord; Substance P | 1994 |
Neurotrophic factors in diabetic neuropathy.
Topics: Animals; Cells, Cultured; Diabetic Neuropathies; Ganglia, Spinal; Naloxone; Naltrexone; Nerve Growth Factors; Paclitaxel | 1995 |
The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dynorphins; In Vitro Techniques; Ion Channels; Naloxone; Naltrexone; Neurons; Patch-Clamp Techniques; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Structure-Activity Relationship; Trigeminal Nerve | 1995 |
Characterization of the spinal antinociceptive activity of constrained peptidomimetic opioids.
Topics: Amino Acid Sequence; Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Injections, Spinal; Male; Mice; Molecular Sequence Data; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Structure-Activity Relationship; Vas Deferens | 1995 |
Capture of wood bison (Bison bison athabascae) using carfentanil-based mixtures.
Topics: Analgesics, Opioid; Animals; Bison; Diprenorphine; Drug Combinations; Female; Fentanyl; Hypnotics and Sedatives; Immobilization; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Northwest Territories; Piperidines; Tranquilizing Agents; Xylazine | 1995 |
Effect of naltrindole on the development of physical dependence on morphine in mice: a behavioral and biochemical study.
Topics: Animals; Behavior, Animal; Body Weight; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Sodium Chloride; Time Factors | 1995 |
Selective actions of central mu and kappa opioid antagonists upon sucrose intake in sham-fed rats.
Topics: Animals; Cerebral Ventricles; Eating; Enkephalin, Leucine-2-Alanine; Infusions, Parenteral; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sucrose | 1995 |
Melatonin modifies prolactin release induced by opiate antagonists in male rats.
Topics: Animals; Injections, Subcutaneous; Male; Melatonin; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Quaternary Ammonium Compounds; Rats; Rats, Wistar | 1995 |
Comparative study of the analgesic and paralytic effects induced by intrathecal dynorphin a in rats.
Topics: Analgesics; Animals; Dynorphins; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Paralysis; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Spinal Cord; Vocalization, Animal | 1995 |
Effects of opioid antagonists naloxone and naltrexone on neuropeptide Y-induced feeding and brown fat thermogenesis in the rat. Neural site of action.
Topics: Adipose Tissue, Brown; Animals; Brain; Energy Metabolism; Feeding Behavior; Male; Naloxone; Naltrexone; Neuropeptide Y; Obesity; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 1995 |
Reductions in body weight following chronic central opioid receptor subtype antagonists during development of dietary obesity in rats.
Topics: Animals; Body Weight; Dietary Fats; Eating; Male; Naloxone; Naltrexone; Narcotic Antagonists; Obesity; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Modification of mu-opioid agonist-induced locomotor activity and development of morphine dependence by diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid, mu; Streptozocin | 1995 |
Blockade of the antinociceptive activity of centrally administered ketorolac by nor-binaltorphimine.
Topics: Analgesia; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Benzoquinones; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Ketorolac Tromethamine; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tolmetin; Tromethamine | 1995 |
Mouse strain differences in in vivo and in vitro immunosuppressive effects of opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Erythrocytes; Female; Immunosuppressive Agents; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Opioid Peptides; Pyrrolidines; Species Specificity; Spleen | 1995 |
The modulation of placental lactogen release by opioids: a role for extracellular calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Analgesics; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Ethylketocyclazocine; Gene Expression Regulation; Humans; Ionomycin; Naloxone; Naltrexone; Narcotics; Pertussis Toxin; Placental Lactogen; Pyrrolidines; Time Factors; Trophoblasts; Virulence Factors, Bordetella | 1993 |
Analysis of central opioid receptor subtype antagonism of hypotonic and hypertonic saline intake in water-deprived rats.
Topics: Animals; Enkephalin, Leucine-2-Alanine; Hypotonic Solutions; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saline Solution, Hypertonic; Water Deprivation | 1995 |
Peripheral kappa-opioid receptors mediate the antinociceptive effect of fedotozine (correction of fetodozine) on the duodenal pain reflex inrat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Benzyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Duodenum; Injections, Intravenous; Injections, Intraventricular; Male; Morphine; Naloxone; Naltrexone; Pain; Propylamines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reflex | 1994 |
Activation of mu-opioid receptor modulates GABAA receptor-mediated currents in isolated spinal dorsal horn neurons.
Topics: Action Potentials; Amino Acid Sequence; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Sequence Data; Muscimol; Naloxone; Naltrexone; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Spinal Cord | 1994 |
A selective CCKB receptor antagonist potentiates, mu-, but not delta-opioid receptor-mediated antinociception in the formalin test.
Topics: Analgesics; Animals; Disulfides; Enkephalins; Formaldehyde; Indoles; Male; Meglumine; Mice; Morphine; Naloxone; Naltrexone; Pain Measurement; Phenylalanine; Receptors, Cholecystokinin; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
kappa-Opioid receptor activates an inwardly rectifying K+ channel by a G protein-linked mechanism: coexpression in Xenopus oocytes.
Topics: Animals; Benzeneacetamides; Cloning, Molecular; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Gene Expression; GTP-Binding Proteins; In Vitro Techniques; Mice; Naloxone; Naltrexone; Oocytes; Pertussis Toxin; Potassium Channels; Pyrrolidines; Receptors, Opioid, kappa; RNA, Complementary; Virulence Factors, Bordetella; Xenopus | 1995 |
Assessment of endogenous enkephalins efficacy in the hot plate test in mice: comparative study with morphine.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalins; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Receptors, Opioid, mu | 1995 |
Long-term exposure to opioid antagonists up-regulates prodynorphin gene expression in rat brain.
Topics: Animals; Brain; Enkephalins; Gene Expression; Male; Naloxone; Naltrexone; Narcotic Antagonists; Protein Precursors; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Endogenous opioids regulate long-term potentiation of synaptic inhibition in the dentate gyrus of rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bicuculline; Electric Stimulation; GABA-A Receptor Antagonists; Hippocampus; Homeostasis; In Vitro Techniques; Long-Term Potentiation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Opioid Peptides; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Time Factors | 1995 |
Complications with the use of carfentanil citrate and xylazine hydrochloride to immobilize domestic horses.
Topics: Analgesics, Opioid; Animals; Animals, Domestic; Fentanyl; Horse Diseases; Horses; Hypertension; Immobilization; Naloxone; Naltrexone; Pulmonary Edema; Tachycardia; Xylazine | 1995 |
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline | 1995 |
Antinociceptive effect of dihydroetorphine in diabetic mice.
Topics: Analgesia; Analgesics, Opioid; Animals; Binding, Competitive; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Evidence that beta-endorphin is an agonist at bovine pineal delta-opioid receptors.
Topics: Animals; beta-Endorphin; Binding, Competitive; Cattle; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; In Vitro Techniques; Naloxone; Naltrexone; Pineal Gland; Receptors, Opioid, delta | 1995 |
Effects of methylnaltrexone on morphine-induced inhibition of contraction in isolated guinea-pig ileum and human intestine.
Topics: Adult; Aged; Animals; Gastrointestinal Motility; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Intestine, Small; Middle Aged; Morphine; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds | 1995 |
Effect of intracerebroventricular beta-funaltrexamine on mu opioid receptors in the rat brain: consideration of binding condition.
Topics: Analgesics; Animals; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tritium | 1995 |
Role of endogenous opioid peptides in central glucocorticoid receptor (GR)-induced decreases in circulating LH in the male rat.
Topics: Androstanols; Animals; Arcuate Nucleus of Hypothalamus; Depression, Chemical; Dexamethasone; Gonadotropin-Releasing Hormone; Injections; Injections, Intraventricular; Injections, Subcutaneous; Luteinizing Hormone; Male; Naloxone; Naltrexone; Neurons; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Opioid; Secretory Rate | 1995 |
Effect of diabetes on the morphine-induced inhibition of gastrointestinal transit.
Topics: Animals; Depression, Chemical; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gastrointestinal Transit; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone | 1995 |
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured | 1994 |
Properties of delta opioid receptor in neuroblastoma NS20Y: receptor activation and neuroblastoma proliferation.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Division; Cyclic AMP; Humans; In Vitro Techniques; Mice; Naloxone; Naltrexone; Neuroblastoma; Pertussis Toxin; Receptors, Opioid, delta; Second Messenger Systems; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Effects of diabetes on the morphine-induced Straub tail reaction in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Reference Values; Tail | 1994 |
Central opioid receptor subtype mediation of isoproterenol-induced drinking in rats.
Topics: Animals; Drinking; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu | 1994 |
Morphine-induced straub tail response: mediated by central mu2-opioid receptor.
Topics: Analgesia; Animals; Female; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid, mu; Tail | 1994 |
Naloxone pretreatment blocks acute morphine-induced sensitization to naltrexone.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Reinforcement Schedule | 1994 |
Effect of selective mu 1, mu 2 and delta 2 opioid receptor agonists on gastric functions in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Acid; Gastric Emptying; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach | 1994 |
Endogenous kappa-opioid systems in opiate withdrawal: role in aversion and accompanying changes in mesolimbic dopamine release.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Conditioning, Operant; Dopamine; Injections, Intraventricular; Limbic System; Male; Microdialysis; Morphine Dependence; Naloxone; Naltrexone; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement, Psychology; Substance Withdrawal Syndrome | 1994 |
Both T cells and macrophages are targets of kappa-opioid-induced immunosuppression.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antibody Formation; Cell Separation; Cells, Cultured; Depression, Chemical; Lymphocyte Activation; Lymphocyte Cooperation; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Naloxone; Naltrexone; Neuroimmunomodulation; Pyrrolidines; Receptors, Opioid, kappa; Rosette Formation; Specific Pathogen-Free Organisms; T-Lymphocytes | 1994 |
kappa-Opioid receptor-transfected cell lines: modulation of adenylyl cyclase activity following acute and chronic opioid treatments.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Benzeneacetamides; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Etorphine; GTP-Binding Proteins; Naloxone; Naltrexone; Opioid Peptides; Pertussis Toxin; Pyrrolidines; Receptors, Opioid, kappa; Virulence Factors, Bordetella | 1995 |
Endogenous opioids and opiate antagonists in autism: brief review of empirical findings and implications for clinicians.
Topics: Autistic Disorder; Brain; Endorphins; Humans; Infant, Newborn; Melatonin; Naloxone; Naltrexone; Self-Injurious Behavior; Serotonin | 1995 |
Peripheral effects of naloxone in mice with acute diarrhea associated with intestinal inflammation.
Topics: Acute Disease; Animals; Benzomorphans; Croton Oil; Diarrhea; Enteritis; Gastrointestinal Motility; Male; Mice; Naloxone; Naltrexone; Quaternary Ammonium Compounds; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1995 |
The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Benzeneacetamides; Cell Membrane; Down-Regulation; In Vitro Techniques; Mice; Naloxone; Naltrexone; Pertussis Toxin; Pyrrolidines; Receptors, Opioid, kappa; Thymoma; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin | 1993 |
Mechanism of action of CCK in avian gastroduodenal motility: evidence for nitric oxide involvement.
Topics: Animals; Arginine; Atropine; Chickens; Duodenum; Electromyography; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Male; Membrane Potentials; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phentolamine; Propranolol; Sincalide; Stomach; Vagotomy | 1993 |
The kappa-opioid receptor agonist U50,488H induces acute physical dependence in guinea-pigs.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Behavior, Animal; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Dependence; Motor Activity; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Inhibiting a spinal dynorphin A component enhances intrathecal morphine antinociception in mice.
Topics: Analgesics; Animals; Cerebral Ventricles; Dynorphins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Spine | 1993 |
Dynorphin A(1-17) mediates midazolam antagonism of morphine antinociception in mice.
Topics: Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Dynorphins; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Midazolam; Morphine; Naloxone; Naltrexone; Pain Measurement; Reaction Time; Spinal Cord | 1993 |
Etonitazene-induced antinociception in mu1 opioid receptor deficient CXBK mice: evidence for a role for mu2 receptors in supraspinal antinociception.
Topics: Animals; Benzimidazoles; Cerebral Ventricles; Dose-Response Relationship, Drug; Enkephalin, Leucine; Hot Temperature; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Receptors, Opioid, mu; Spinal Cord | 1994 |
Kappa opioids inhibit induction of long-term potentiation in the dentate gyrus of the guinea pig hippocampus.
Topics: Animals; Benzeneacetamides; Dynorphins; Electric Stimulation; Guinea Pigs; Hippocampus; Long-Term Potentiation; Male; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Synaptic Transmission | 1994 |
Mu- and kappa-opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons.
Topics: Analgesics; Animals; Benzeneacetamides; Calcium; Calcium Channels; Dynorphins; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reference Values; Sensitivity and Specificity | 1994 |
A mechanism of action for morphine-induced immunosuppression: corticosterone mediates morphine-induced suppression of natural killer cell activity.
Topics: Animals; Cells, Cultured; Corticosterone; Female; Immunosuppressive Agents; Killer Cells, Natural; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Spleen | 1994 |
Nalorphine as a stimulus in drug discrimination learning: assessment of the role of mu- and kappa-receptor subtypes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Diprenorphine; Discrimination Learning; Dose-Response Relationship, Drug; Female; Generalization, Stimulus; Nalorphine; Naloxone; Naltrexone; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1994 |
Morphine reduces the release of met-enkephalin-like material from the rat spinal cord in vivo by acting at delta opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1994 |
Species difference in the modulatory effect of kappa agonist on 5-HT release from ground squirrel and rat hippocampus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Aging; Animals; Dose-Response Relationship, Drug; Female; Hippocampus; In Vitro Techniques; Male; Naloxone; Naltrexone; Potassium; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sciuridae; Serotonin; Species Specificity; Tetrodotoxin | 1994 |
Beta-funaltrexamine blockade of opioid-induced inhibition of somatostatin secretion from rat stomach.
Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gastric Inhibitory Polypeptide; Gastric Mucosa; In Vitro Techniques; Male; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin | 1994 |
Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.
Topics: Amino Acid Sequence; Analgesia; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Naloxone; Naltrexone; Oligopeptides; Peptide Fragments; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide | 1994 |
Streptozotocin-induced diabetes selectively reduces antinociception mediated by mu 1-opioid receptors, but not that mediated by mu 2-opioid receptors.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid, mu; Spinal Cord | 1994 |
Microwave irradiation affects radial-arm maze performance in the rat.
Topics: Analysis of Variance; Animals; Learning; Male; Memory; Microwaves; Naloxone; Naltrexone; Physostigmine; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors | 1994 |
Characterization of opioid binding sites in the neural and intermediate lobe of the rat pituitary gland by quantitative receptor autoradiography.
Topics: Amino Acid Sequence; Analgesics; Animals; Autoradiography; Benzomorphans; Binding, Competitive; Densitometry; Enkephalins; Ligands; Male; Molecular Sequence Data; Naloxone; Naltrexone; Pituitary Gland; Pituitary Gland, Posterior; Protein Precursors; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, kappa | 1994 |
TRIMU-5, a mu 2-opioid receptor agonist, stimulates the hypothalamo-pituitary-adrenal axis.
Topics: Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Kinetics; Male; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1994 |
Lack of involvement of delta-1 opioid receptors in the development of physical dependence on morphine in mice.
Topics: Affinity Labels; Animals; Diarrhea; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Injections, Spinal; Isothiocyanates; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid, delta; Substance-Related Disorders | 1994 |
Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Base Sequence; Benzeneacetamides; Binding Sites; Cell Line; Chlorocebus aethiops; Cloning, Molecular; Colforsin; Cyclic AMP; Enkephalin, Leucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Naltrexone; Oligodeoxyribonucleotides; Protein Structure, Secondary; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Recombinant Fusion Proteins; Recombinant Proteins; Transfection | 1994 |
Involvement of kappa-opioid receptors in opioid dependence/withdrawal: studies using butorphanol.
Topics: Animals; Butorphanol; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
Role of vagal afferents in the antinociception produced by morphine and U-50,488H in the colonic pain reflex in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Blood Pressure; Colon; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Neurons, Afferent; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Vagotomy; Vagus Nerve | 1994 |
The use of specific opioid agonists and antagonists to delineate the vagally mediated antinociceptive and cardiovascular effects of intravenous morphine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analysis of Variance; Animals; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heart Rate; Hexamethonium; Hexamethonium Compounds; Indoles; Injections, Intravenous; Male; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors; Vagotomy; Vagus Nerve | 1993 |
Endogenous dynorphin modulates calcium-mediated antinociception in mice.
Topics: Animals; Calcium; Dynorphins; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Nociceptors; Peptide Fragments; Phenobarbital | 1993 |
Repeated exposure of rat pups to isolation attenuates isolation-induced ultrasonic vocalization rates: reversal with naltrexone.
Topics: Animals; Arousal; Dose-Response Relationship, Drug; Female; Habituation, Psychophysiologic; Male; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Social Isolation; Vocalization, Animal | 1994 |
Interaction of beta-endorphin and GABAergic drugs in the regulation of memory storage.
Topics: Animals; Avoidance Learning; beta-Endorphin; Bicuculline; Conditioning, Classical; Dose-Response Relationship, Drug; Electroshock; Fear; Injections, Intraperitoneal; Male; Mice; Muscimol; Naloxone; Naltrexone; Picrotoxin; Reaction Time; Receptors, GABA; Receptors, Opioid; Retention, Psychology | 1993 |
Characterization of the mu-opioid receptors on SH-SY5Y cells using beta-funaltrexamine (beta-FNA) and naloxonazine.
Topics: Analgesics; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid, mu; Tumor Cells, Cultured | 1993 |
Influence of selective opiate antagonists on striatal acetylcholine and dopamine release.
Topics: Acetylcholine; Animals; Corpus Striatum; Dopamine; Electric Stimulation; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxidopamine; Rats; Rats, Wistar | 1993 |
Antagonistic effects of the selective, competitive N-methyl-D-aspartate (NMDA) receptor antagonist, NPC 12626, on kappa opiate-induced analgesia in male deer mice.
Topics: Amino Acids; Analgesics; Animals; Benzeneacetamides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Nociceptors; Pain Measurement; Peromyscus; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1994 |
The role of multiple opioid receptors in the maintenance of stimulation-induced feeding.
Topics: Amino Acid Sequence; Animals; Differential Threshold; Dose-Response Relationship, Drug; Eating; Electric Stimulation; Hypothalamic Area, Lateral; Male; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1994 |
Effect of a peripheral and a central acting opioid antagonist on the testicular response to stress in rats.
Topics: Aldehyde-Lyases; Animals; Corticosterone; Cytochrome P-450 Enzyme System; Immobilization; Kinetics; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Steroid 17-alpha-Hydroxylase; Stress, Psychological; Testis; Testosterone | 1994 |
Acute sensitization to opioid antagonists.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reinforcement Schedule; Stereoisomerism | 1994 |
Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in mice.
Topics: Analgesics; Animals; Body Weight; Drug Tolerance; Etorphine; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Substance-Related Disorders | 1993 |
Differential effects of specific delta and kappa opioid receptor antagonists on the bidirectional dose-dependent effect of systemic naloxone in arthritic rats, an experimental model of persistent pain.
Topics: Analysis of Variance; Animals; Arthritis; Benzomorphans; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Vocalization, Animal | 1993 |
Multiple opioid system involvement in the mediation of parasitic-infection induced analgesia.
Topics: Analgesia; Animals; Coccidiosis; Endorphins; Enkephalin, Leucine; Host-Parasite Interactions; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists | 1993 |
Naloxone-induced analgesia: involvement of kappa-opiate receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; Benzomorphans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1993 |
Opioid antagonist-induced receptor upregulation: effects of concurrent agonist administration.
Topics: Animals; Brain; Drug Combinations; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Fentanyl; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Up-Regulation | 1994 |
Delta-opioid receptor antagonists attenuate motor activity induced by amphetamine but not cocaine.
Topics: Amphetamine; Animals; Cocaine; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 1993 |
The effect of nalmefene on pulsatile secretion of luteinizing hormone and prolactin in men.
Topics: Adult; Endorphins; Humans; Luteinizing Hormone; Male; Naloxone; Naltrexone; Prolactin; Secretory Rate | 1993 |
Sex differences in the antinociceptive effects of the enkephalinase inhibitor, SCH 34826.
Topics: Analgesia; Analgesics; Animals; Dioxolanes; Dipeptides; Enkephalin, Leucine; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Peromyscus; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Restraint, Physical; Sex Characteristics; Stress, Psychological | 1993 |
Long-term naltrexone treatment reduces the exaggerated insulin secretion in patients with polycystic ovary disease.
Topics: Adult; Endorphins; Female; Glucose Tolerance Test; Gonadal Steroid Hormones; Humans; Hyperinsulinism; Insulin; Naloxone; Naltrexone; Obesity; Polycystic Ovary Syndrome; Time Factors | 1993 |
The role of endogenous opioids as mediators of the hypothermic effects of intrathecally administered calcium and calcitonin gene-related peptide in mice.
Topics: Animals; Body Temperature Regulation; Calcitonin Gene-Related Peptide; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Hypothalamus; Hypothermia, Induced; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Time Factors | 1993 |
Opioid-induced stimulation of fetal respiratory activity by [D-Ala2]deltorphin I.
Topics: Animals; Dose-Response Relationship, Drug; Electromyography; Female; Fetus; Indoles; Injections, Intraventricular; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pregnancy; Receptors, Opioid, delta; Respiration; Sheep | 1993 |
Relative involvement of supraspinal and spinal mu opioid receptors in morphine dependence in mice.
Topics: Animals; Brain; Cerebral Ventricles; Diarrhea; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine Dependence; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome | 1993 |
Involvement of delta 2 opioid receptors in the development of morphine dependence in mice.
Topics: Animals; Enkephalin, Leucine; Isothiocyanates; Male; Mice; Morphinans; Morphine Dependence; Naloxone; Naltrexone; Receptors, Opioid, delta; Substance Withdrawal Syndrome; Thiocyanates | 1993 |
Involvement of mu1 and mu2 opioid receptor subtypes in tail-pinch feeding in rats.
Topics: Animals; Arousal; Enkephalin, Leucine-2-Alanine; Feeding Behavior; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1993 |
Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains.
Topics: Analgesia; Animals; Brain Stem; Drug Administration Routes; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid, mu; Species Specificity; Spinal Cord | 1993 |
Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anticonvulsants; Epilepsy; Female; Male; Mice; Mice, Inbred DBA; Motor Activity; Naloxone; Naltrexone; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid, kappa; Serine | 1993 |
Effects of the kappa-opioid agonist U50,488 on parturition in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Female; Infusions, Intravenous; Injections, Intravenous; Labor, Obstetric; Male; Morphine; Naloxone; Naltrexone; Oxytocin; Pregnancy; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Opioid, kappa; Uterine Contraction | 1993 |
Withdrawal contractures of guinea-pig isolated ileum after acute activation of kappa-opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Nifedipine; Pyrrolidines; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1993 |
L-arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Brain; Cyclic GMP; Endorphins; Enkephalin, Methionine; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain Measurement; Spinal Cord | 1993 |
Evidence for an opioid inhibitory effect on T cell proliferation.
Topics: Adult; Animals; beta-Endorphin; Cell Division; Concanavalin A; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotics; Phytohemagglutinins; Rats; Rats, Sprague-Dawley; Receptors, Opioid; T-Lymphocytes | 1993 |
Blockade of cannabinoid-induced antinociception by norbinaltorphimine, but not N,N-diallyl-tyrosine-Aib-phenylalanine-leucine, ICI 174,864 or naloxone in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Dronabinol; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Infusions, Intravenous; Injections, Spinal; Mice; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta | 1993 |
Opioid control of the release of calcitonin gene-related peptide-like material from the rat spinal cord in vivo.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcitonin Gene-Related Peptide; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Spinal; Iodine Radioisotopes; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1993 |
Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats.
Topics: Animals; Heroin; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration | 1993 |
CRF alters the infundibular LHRH secretory system from the medial preoptic area of female rats: possible involvement of opioid receptors.
Topics: Animals; Corticotropin-Releasing Hormone; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Luteinizing Hormone; Naloxone; Naltrexone; Ovariectomy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1993 |
Dose-dependent antagonism of spinal opioid receptor agonists by naloxone and naltrindole: additional evidence for delta-opioid receptor subtypes in the rat.
Topics: Analgesics; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; In Vitro Techniques; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1993 |
Alpha-interferon inhibits adrenocortical secretion via mu 1-opioid receptors in the rat.
Topics: Animals; Corticosterone; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Injections, Intraventricular; Interferon-alpha; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Swimming | 1993 |
Mode of action of interleukin-1 in suppression of pituitary LH release in castrated male rats.
Topics: Animals; Corticotropin-Releasing Hormone; Depression, Chemical; Hypothalamus; Injections, Intraventricular; Interleukin-1; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Orchiectomy; Pituitary Gland; Rats; Receptors, Opioid | 1993 |
Opioid-induced suppression of rat testicular function.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Extracellular Space; Gonadotropins; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Male; Morphine; Naloxone; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Testis; Testosterone; Time Factors | 1993 |
The highly selective delta agonist BUBU induces an analgesic effect in normal and arthritic rat and this action is not affected by repeated administration of low doses of morphine.
Topics: Analgesics; Animals; Arthritis, Experimental; Drug Administration Schedule; Drug Interactions; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Reference Values; Vocalization, Animal | 1993 |
Involvement of spinal kappa opioid receptors in a type of footshock induced analgesia in mice.
Topics: Analgesia; Animals; Cerebral Ventricles; Electroshock; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Receptors, Opioid, kappa; Spinal Cord; Stress, Psychological | 1993 |
Selective opioid receptor agonists modulate mechanical allodynia in an animal model of neuropathic pain.
Topics: Analgesics; Animals; Benzeneacetamides; Benzomorphans; Disease Models, Animal; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vocalization, Animal | 1993 |
DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.
Topics: Analgesics; Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Male; Naloxone; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1993 |
Effect of delayed weaning on opioid receptor control of swim stress-induced antinociception in the developing rat.
Topics: Alfentanil; Analgesia; Animals; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stress, Psychological; Swimming; Weaning | 1993 |
Role of mu 1- and delta-opioid receptors in modulation of fetal EEG and respiratory activity.
Topics: Animals; Electroencephalography; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fetal Movement; Fetus; Morphine; Naloxone; Naltrexone; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Sheep | 1993 |
Chronic kappa opioid receptor antagonism produces supersensitivity to U-50,488H at the hypothalamo-pituitary-adrenocortical (HPA) axis level.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Body Weight; Corticosterone; Dose-Response Relationship, Drug; Hyperalgesia; Hypothalamo-Hypophyseal System; Male; Naloxone; Naltrexone; Pituitary-Adrenal System; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sensitivity and Specificity; Sodium Chloride | 1993 |
Central opioid receptor subtype antagonists differentially reduce intake of saccharin and maltose dextrin solutions in rats.
Topics: Animals; Drinking Behavior; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Saccharin | 1993 |
Antagonist effects of beta-funaltrexamine and naloxonazine on alfentanil-induced antinociception and muscle rigidity in the rat.
Topics: Alfentanil; Analgesia; Animals; Electromyography; Male; Muscle Rigidity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar | 1993 |
Effects of a 60 Hz magnetic field on central cholinergic systems of the rat.
Topics: Animals; Brain; Choline; Electromagnetic Fields; Male; Naloxone; Naltrexone; Parasympathetic Nervous System; Rats; Rats, Sprague-Dawley | 1993 |
Influence of hyperkalaemia and ischaemia on non-receptor-mediated cardiac electrophysiological effects of naloxone.
Topics: Action Potentials; Animals; Culture Techniques; Dose-Response Relationship, Drug; Electrophysiology; Heart Conduction System; Hyperkalemia; Morphine; Myocardial Ischemia; Naloxone; Naltrexone; Narcotic Antagonists; Rabbits; Refractory Period, Electrophysiological | 1993 |
Ultrashort noninvasive opiate detoxification.
Topics: Adult; Heroin Dependence; Humans; Male; Midazolam; Naloxone; Naltrexone; Ondansetron; Substance Withdrawal Syndrome; Time Factors | 1993 |
Measurement of naloxone in plasma using high-performance liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Naloxone; Naltrexone; Oxidation-Reduction; Reference Values; Reproducibility of Results; Sensitivity and Specificity | 1993 |
Opioid and nonopioid interactions in two forms of stress-induced analgesia.
Topics: Analgesia; Animals; Body Temperature; Cold Temperature; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Reaction Time; Skin Temperature; Social Behavior; Stress, Psychological | 1993 |
Duration of opioid antagonism by nalmefene and naloxone in the dog: an integrated pharmacokinetic/pharmacodynamic comparison.
Topics: Animals; Blood Gas Monitoring, Transcutaneous; Dogs; Female; Fentanyl; Infusions, Intravenous; Models, Biological; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Respiration | 1995 |
Kappa opioid receptors participate in nerve growth factor-induced hyperalgesia.
Topics: Animals; Female; Humans; Hyperalgesia; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Growth Factors; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins | 1995 |
Discriminative stimulus properties of morphine mediated by mu 1-opioid receptors.
Topics: Analgesics, Opioid; Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred F344; Receptors, Opioid, mu | 1995 |
Attenuation of morphine tolerance and dependence with the highly selective delta-opioid receptor antagonist TIPP[psi].
Topics: Animals; Behavior, Animal; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Receptors, Opioid, delta; Substance Withdrawal Syndrome; Tetrahydroisoquinolines | 1995 |
Duration of opioid antagonism by nalmefene and naloxone in the dog. A nonparametric pharmacodynamic comparison based on generalized cross-validated spline estimation.
Topics: Analysis of Variance; Animals; Carbon Dioxide; Computer Simulation; Cross-Over Studies; Dogs; Drug Tolerance; Fentanyl; Injections, Intravenous; Male; Models, Statistical; Naloxone; Naltrexone; Narcotic Antagonists; Respiratory Insufficiency; Time Factors | 1995 |
Opioid antagonists naloxone, beta-funaltrexamine and naltrindole, but not nor-binaltorphimine, reverse the increased hindpaw withdrawal latency in rats induced by intrathecal administration of the calcitonin gene-related peptide antagonist CGRP8-37.
Topics: Animals; Calcitonin Gene-Related Peptide; Hindlimb; Hot Temperature; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Stress, Mechanical | 1995 |
Electrical stimulation at traditional acupuncture sites in periphery produces brain opioid-receptor-mediated antinociception in rats.
Topics: Acupuncture Therapy; Analgesia; Animals; Brain; Electric Stimulation; Male; Naloxone; Naltrexone; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin | 1996 |
Opioid antagonists and antisera to endogenous opioids increase the nociceptive response to formalin: demonstration of an opioid kappa and delta inhibitory tone.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Formaldehyde; Immune Sera; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1996 |
Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans.
Topics: Adult; Analgesics, Opioid; Buprenorphine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1996 |
Interaction of opioids with antidepressant-induced antinociception.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clomipramine; Drug Combinations; Female; Imipramine; Male; Maprotiline; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Random Allocation; Selective Serotonin Reuptake Inhibitors; Zimeldine | 1995 |
Tonic endogenous opioid inhibition of visceral noxious information in rabbits.
Topics: Age Factors; Animals; Benzomorphans; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Injections, Intramuscular; Injections, Spinal; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Rabbits; Receptors, Opioid | 1996 |
Antinociceptive and behavioral effects of synthetic deltorphin analogs.
Topics: Analysis of Variance; Animals; Catalepsy; Dose-Response Relationship, Drug; Injections, Intraventricular; Locomotion; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Central antinociceptive effect of L-ornithine, a metabolite of L-arginine, in rats and mice.
Topics: Analgesia; Animals; Arginine; Carrageenan; Citrulline; Dipeptides; Dose-Response Relationship, Drug; Excipients; Hyperalgesia; Injections, Intraventricular; Leucine; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Ornithine; Pain Measurement; Protease Inhibitors; Rats | 1996 |
Differential effects of morphine-6-glucuronide, an active metabolite of morphine, and morphine on locomotor activity in mice: involvement of the opioid receptor.
Topics: Animals; Injections, Subcutaneous; Locomotion; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1996 |
Distribution of c-Fos in guinea-pig brain following morphine withdrawal.
Topics: Analgesics, Opioid; Animals; Brain Chemistry; Female; Guinea Pigs; Locomotion; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Proto-Oncogene Proteins c-fos; Substance Withdrawal Syndrome | 1996 |
Role of delta-opioid receptors in mediating the aversive stimulus effects of morphine withdrawal in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Substance Withdrawal Syndrome | 1996 |
Antinociceptive and antitussive effects of morphine in the DA-bg/bg (beige) rat.
Topics: Analgesics, Opioid; Animals; Capsaicin; Cough; Female; Male; Morphine; Naloxone; Naltrexone; Pain; Rats; Rats, Inbred Strains; Species Specificity | 1996 |
Morphine stimulates phagocytosis of Mycobacterium tuberculosis by human microglial cells: involvement of a G protein-coupled opiate receptor.
Topics: Adjuvants, Immunologic; Brain; Cells, Cultured; Cholera Toxin; GTP-Binding Proteins; Humans; Microglia; Morphine; Mycobacterium tuberculosis; Naloxone; Naltrexone; Narcotic Antagonists; Neuroimmunomodulation; Pertussis Toxin; Phagocytosis; Receptors, Opioid; Signal Transduction; Virulence Factors, Bordetella | 1995 |
Ocular action of an opioid peptide, DPDPE.
Topics: Administration, Topical; Analgesics; Animals; Ciliary Body; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Injections, Intravenous; Intraocular Pressure; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rabbits | 1996 |
Effects of melatonin in vivo upon luteinizing hormone and prolactin releases induced by opiate receptor antagonists in adult male rats.
Topics: Animals; Luteinizing Hormone; Male; Melatonin; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Quaternary Ammonium Compounds; Rats; Rats, Wistar | 1996 |
Opioid receptor selectivity alteration by single residue replacement: synthesis and activity profile of [Dmt1]deltorphin B.
Topics: Animals; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Rabbits; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Opioid antagonist profile of SC nor-binaltorphimine in the formalin paw assay.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1996 |
Alcohol drinking is reduced by a mu 1- but not by a delta-opioid receptor antagonist in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking; Eating; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraperitoneal; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Investigation of the effects of opiate antagonists infused into the nucleus accumbens on feeding and sucrose drinking in rats.
Topics: Animals; Drinking Behavior; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Satiation; Sucrose | 1996 |
Intrathecal Tyr-W-MIF-1 produces potent, naloxone-reversible analgesia modulated by alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Desipramine; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Molecular Sequence Data; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-2; Yohimbine | 1996 |
Opioid and nonopioid swim stress-induced analgesia: a parametric analysis in mice.
Topics: Analgesia; Animals; Body Temperature; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Measurement; Stress, Psychological; Swimming | 1996 |
Opioid antagonists and the sexual satiation phenomenon.
Topics: Animals; Copulation; Ejaculation; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Satiety Response; Sexual Behavior, Animal | 1995 |
The influence of opioid antagonists on the discriminative stimulus effects of ethanol.
Topics: Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar | 1996 |
Naltrindole sensitive delta 2 opioid receptor mediates invertebrate immunocyte activation.
Topics: Animals; Bivalvia; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Humans; Immune System; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta | 1995 |
Reductions in locomotor activity following central opioid receptor subtype antagonists in rats.
Topics: Animals; Enkephalins; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley | 1996 |
Effects of the delta opioid against BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure.
Topics: Analgesics; Animals; Benzamides; Benzomorphans; Columbidae; Discrimination, Psychological; Female; Fentanyl; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Receptors, Opioid, delta | 1996 |
The NMDA receptor antagonist MK-801 differentially modulates mu and kappa opioid actions in spinal cord in vitro.
Topics: Analgesics; Animals; Animals, Newborn; Benzeneacetamides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; In Vitro Techniques; Membrane Potentials; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1996 |
Endogenous opioids acting at a medullary mu-opioid receptor contribute to the behavioral antinociception produced by GABA antagonism in the midbrain periaqueductal gray.
Topics: Animals; Bicuculline; Brain Mapping; GABA Antagonists; Male; Medulla Oblongata; Mesencephalon; Microinjections; Models, Neurological; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Time Factors | 1996 |
Effects of selective opioid receptor antagonists on morphine-induced changes in striatal and limbic dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
alpha-Adrenoceptor and opioid receptor modulation of clonidine-induced antinociception.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Prazosin; Receptors, Opioid; Yohimbine | 1996 |
Rapid opiate detoxification.
Topics: Adult; Anesthetics, Intravenous; Critical Care; Female; Heroin Dependence; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Neuromuscular Nondepolarizing Agents; Propofol; Respiration, Artificial; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome; Vecuronium Bromide | 1996 |
Effects of the blockade of opioid receptor on defensive reactions elicited by electrical stimulation within the deep layers of the superior colliculus and DPAG.
Topics: Animals; Brain Mapping; Electric Stimulation; Escape Reaction; Male; Naloxone; Naltrexone; Narcotic Antagonists; Periaqueductal Gray; Rats; Rats, Wistar; Superior Colliculi | 1996 |
kappa-opioid receptor expression defines a phenotypically distinct subpopulation of astroglia: relationship to Ca2+ mobilization, development, and the antiproliferative effect of opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Astrocytes; Benzeneacetamides; Bromodeoxyuridine; Calcium; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Immunohistochemistry; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nifedipine; Phenotype; Pyrrolidines; Receptors, Opioid, kappa; Thapsigargin; Time Factors | 1996 |
Opioid receptor-mediated control of acetylcholine release in human neocortex tissue.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetylcholine; Adolescent; Adult; Aged; Analgesics; Analysis of Variance; Baclofen; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; GABA Agonists; Humans; Male; Middle Aged; Muscimol; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, delta; Tetrodotoxin | 1996 |
Role of opioid receptors (mu, delta 1, delta 2) in modulating responses of nociceptive neurons in the superficial and deeper dorsal horn of the medulla (trigeminal nucleus caudalis) in the rat.
Topics: Animals; Benzylidene Compounds; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons; Nociceptors; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Trigeminal Caudal Nucleus | 1996 |
Different central opioid receptor subtype antagonists modify maltose dextrin and deprivation-induced water intake in sham feeding and sham drinking rats.
Topics: Animals; Dose-Response Relationship, Drug; Drinking; Eating; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Deprivation | 1996 |
Neuropharmacological characterization of local ibogaine effects on dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Ibogaine; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 1996 |
Antidepressant-like effects of CCK(B) receptor antagonists: involvement of the opioid system.
Topics: Animals; Antidepressive Agents; Benzodiazepinones; Devazepide; Disulfides; Endorphins; Male; Mice; Naloxone; Naltrexone; Phenylalanine; Phenylurea Compounds; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1996 |
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1997 |
Inhibition of the LH surge in cyclic rats by stress is not mediated by opioids.
Topics: Animals; Female; Luteinizing Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Proestrus; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological | 1997 |
Effects of mu-, delta- and kappa-opioid antagonists in atrial preparations from nonfailing and failing human hearts.
Topics: Adult; Aged; Depression, Chemical; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Heart Valve Diseases; Humans; In Vitro Techniques; Male; Middle Aged; Mitral Valve; Myocardial Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Acute and chronic effects of opioids on delta and mu receptor activation of G proteins in NG108-15 and SK-N-SH cell membranes.
Topics: Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hybrid Cells; Membrane Proteins; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neuroblastoma; Protein Binding; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes; Time Factors | 1997 |
Nalbuphine coadministered with morphine prevents tolerance and dependence.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Male; Morphine; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Pyrrolidines; Rats; Rats, Sprague-Dawley | 1997 |
Opioid receptor antagonists attenuate heat stress-induced reduction in cerebral blood flow, increased blood-brain barrier permeability, vasogenic edema and cell changes in the rat.
Topics: Animals; Blood-Brain Barrier; Body Temperature; Brain; Brain Edema; Cerebrovascular Circulation; Heat Stress Disorders; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar | 1997 |
Modulation of neurotransmitter release by opioid mu- and kappa-receptors from adrenergic terminals in the myenteric plexus of the guinea-pig colon: effect of alpha 2-autoreceptor blockade.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Myenteric Plexus; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Norepinephrine; Pyrrolidines; Receptors, Adrenergic, alpha-2; Receptors, Opioid, kappa; Receptors, Opioid, mu; Yohimbine | 1997 |
Actions of beta-endorphin peptides on the contractions of mouse diaphragm muscle.
Topics: Animals; Benzylidene Compounds; beta-Endorphin; Diaphragm; Dipeptides; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Mice; Mice, Inbred C57BL; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neostigmine; Oligopeptides; Peptide Fragments | 1997 |
Opioid growth factor is present in human and mouse gastrointestinal tract and inhibits DNA synthesis.
Topics: Animals; Cells, Cultured; Circadian Rhythm; DNA; DNA Replication; Enkephalin, Methionine; Esophagus; Gastric Mucosa; Growth Substances; Homeostasis; Humans; Intestinal Mucosa; Intestine, Large; Intestine, Small; Kinetics; Male; Mice; Mice, Inbred C57BL; Mitotic Index; Mucous Membrane; Naloxone; Naltrexone; Receptors, Opioid; Thymidine; Time Factors | 1997 |
5-HT spinal antinociception involves mu opioid receptors: cross tolerance and antagonist studies.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Hot Temperature; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, mu; Serotonin; Serotonin Antagonists; Spinal Cord | 1997 |
Antinociceptive effect of buprenorphine in mu1-opioid receptor deficient CXBK mice.
Topics: Animals; Buprenorphine; Male; Mice; Mice, Inbred C57BL; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Species Specificity | 1997 |
Effect of prior nicotine treatment on drug induced changes in serum LH concentrations in rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Gonadotropin-Releasing Hormone; Haloperidol; Luteinizing Hormone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1997 |
Antinociceptive and immunosuppressive effects of opiate drugs: a structure-related activity study.
Topics: Animals; Cell Division; Codeine; Hydromorphone; Immune System; Immunosuppression Therapy; Interleukin-2; Male; Mice; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotics; Oxycodone; Structure-Activity Relationship | 1997 |
Extraordinary potency of a novel delta opioid receptor agonist is due in part to increased efficacy.
Topics: Animals; Biological Assay; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Peptides, Cyclic; Receptors, Opioid, delta; Vas Deferens | 1997 |
Participation of central kappa-opioid receptor in arrhythmogenesis.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Arrhythmias, Cardiac; Dynorphins; Epinephrine; Hexamethonium; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa | 1997 |
Effects of kappa opioids on cocaine self-administration by rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Circadian Rhythm; Cocaine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Female; Macaca mulatta; Male; Naloxone; Naltrexone; Pyrrolidines; Receptors, Opioid, kappa; Self Administration; Substance-Related Disorders | 1997 |
In vivo binding of [125I]NH2-carfentanil to mu opioid receptors in mouse brain.
Topics: Animals; Autoradiography; Brain; Fentanyl; Injections, Intraperitoneal; Iodine Radioisotopes; Logistic Models; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Radioligand Assay; Receptors, Opioid, mu | 1994 |
Involvement of opioid mu 1 receptors in morphine-induced conditioned place preference in rats.
Topics: Analgesics, Opioid; Animals; Body Temperature; Catalepsy; Conditioning, Operant; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, mu | 1997 |
[Central K1-opiate receptors and mechanisms of arrhythmogenesis].
Topics: Animals; Arrhythmias, Cardiac; Blood-Brain Barrier; Brain; Dynorphins; Ganglionic Blockers; Heart; Hexamethonium; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Parasympathetic Nervous System; Rats; Rats, Wistar; Receptors, Opioid, kappa | 1997 |
Brain and spinal cord distribution of biphalin: correlation with opioid receptor density and mechanism of CNS entry.
Topics: Analgesics; Animals; Binding, Competitive; Brain; Enkephalins; Iodine Radioisotopes; Kinetics; Models, Chemical; Naloxone; Naltrexone; Narcotic Antagonists; Organ Specificity; Peptides; Radioisotope Dilution Technique; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Tissue Distribution | 1997 |
Food intake and food choice: the role of the endogenous opioid peptides in the marsupial Sminthopsis crassicaudata.
Topics: Animals; Diet; Eating; Endorphins; Energy Intake; Food Preferences; Male; Marsupialia; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Prejunctional modulation by nociceptin of nerve-mediated inotropic responses in guinea-pig left atrium.
Topics: Animals; Atrial Function; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Naloxone; Naltrexone; Neuromuscular Junction; Neurons, Afferent; Nociceptin; Opioid Peptides; Sensory Receptor Cells | 1997 |
Naltrindole, a selective delta-opioid receptor antagonist, potentiates the lethal effects of cocaine by a central mechanism of action.
Topics: Animals; Blood Pressure; Central Nervous System; Cisterna Magna; Cocaine; Drug Synergism; Heart Rate; Infusions, Intravenous; Injections; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Seizures | 1997 |
The possible role of protein phosphatase 2A in the sodium sensitivity of the receptor binding of opiate antagonists naloxone and naltrindole.
Topics: Animals; Corpus Striatum; Enzyme Activation; Enzyme Inhibitors; Male; Marine Toxins; Naloxone; Naltrexone; Narcotic Antagonists; Oxazoles; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylase a; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Rats, Wistar; Receptors, Opioid; Sensitivity and Specificity; Sodium Chloride; Substrate Specificity; Tritium | 1997 |
Antinociceptive effects of morphine and U-50,488H on vaginal distension in the anesthetized rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Animals; Blood Pressure; Cardiovascular System; Estrus; Female; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Vaginal Diseases | 1997 |
The effect of opioid antagonists in local regulation of testicular response to acute stress in adult rats.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Injections; Male; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Testis; Testosterone | 1997 |
Anatomical distribution of mu, delta, and kappa opioid- and nociceptin/orphanin FQ-stimulated [35S]guanylyl-5'-O-(gamma-thio)-triphosphate binding in guinea pig brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Animals; Autoradiography; Brain Chemistry; Cerebellum; Diencephalon; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Medulla Oblongata; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pons; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Telencephalon | 1997 |
Conditioned immunomodulation: investigations of the role of endogenous activity at mu, kappa, and delta opioid receptor subtypes.
Topics: Animals; Avoidance Learning; Cell Division; Conditioning, Classical; Electroshock; Immune System; Killer Cells, Natural; Lipopolysaccharides; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Lew; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spleen | 1997 |
Discriminative stimulus effects of the mixed-opioid agonist/antagonist dezocine: cross-substitution by mu and delta opioid agonists.
Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Columbidae; Cycloparaffins; Discrimination Learning; Female; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, mu; Tetrahydronaphthalenes | 1997 |
Kappa-opioid restraint of oxytocin secretion: plasticity through pregnancy.
Topics: Animals; Basal Metabolism; Cholecystokinin; Female; Naloxone; Naltrexone; Oxytocin; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Secretory Rate | 1997 |
Characterization of opiate binding sites on the goldfish (Carassius auratus L.) pronephric leukocytes.
Topics: Animals; Binding Sites; Goldfish; Leukocytes; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, mu | 1997 |
Opioid receptor-mediated inhibition of omega-conotoxin GVIA-sensitive calcium channel currents in rat intracardiac neurons.
Topics: Acetylcholine; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Benzomorphans; Calcium; Calcium Channels; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Heart Conduction System; Ion Channel Gating; Ion Transport; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; omega-Conotoxin GVIA; Parasympathetic Nervous System; Patch-Clamp Techniques; Peptides; Pertussis Toxin; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Virulence Factors, Bordetella | 1998 |
Morphine-6-glucuronide-induced locomotor stimulation in mice: role of opioid receptors.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Derivatives; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1998 |
Identification of opioid receptor subtypes in antinociceptive actions of supraspinally-administered mitragynine in mice.
Topics: Analgesics; Animals; Drug Synergism; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Receptors, Opioid; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids | 1998 |
Supraspinal flumazenil inhibits the antianalgesic action of spinal dynorphin A (1-17).
Topics: Analgesia; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Physostigmine | 1998 |
Clinical experience with antagonist-induced opiate withdrawal under anaesthesia.
Topics: Anesthesia; Hospitalization; Humans; Inactivation, Metabolic; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders | 1998 |
Rapid opioid detoxification.
Topics: Adult; Drug Implants; Fentanyl; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders | 1998 |
Dynorphin uses a non-opioid mechanism to potentiate N-methyl-D-aspartate currents in single rat periaqueductal gray neurons.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Action Potentials; Analgesics, Non-Narcotic; Animals; Drug Synergism; Dynorphins; N-Methylaspartate; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Patch-Clamp Techniques; Peptide Fragments; Periaqueductal Gray; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1998 |
Beta-funaltrexamine discriminates between two subtypes of mu2-opioid receptors in electrically stimulated longitudinal muscle of guinea pig ileum.
Topics: Acetylcholine; Animals; Binding, Competitive; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Endings; Receptors, Opioid, mu; Tetrodotoxin | 1998 |
The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds.
Topics: Abdominal Muscles; Acetic Acid; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cyclobutanes; Dothiepin; Male; Maprotiline; Mice; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Neurotransmitter Uptake Inhibitors; Opioid Peptides; Pain Measurement; Paroxetine; Protease Inhibitors; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Thiorphan | 1998 |
Affinity profiles of novel delta-receptor selective benzofuran derivatives of non-peptide opioids.
Topics: Animals; Benzeneacetamides; Benzofurans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Naltrexone; Oligopeptides; Oxycodone; Oxymorphone; Pyrrolidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tritium | 1998 |
Rapid opioid detoxification under anaesthesia.
Topics: Adult; Anesthesia, General; Atracurium; Drug Therapy, Combination; Follow-Up Studies; Gastrointestinal Agents; Humans; Hypnotics and Sedatives; Male; Midazolam; Naloxone; Naltrexone; Narcotic Antagonists; Nicotinic Antagonists; Octreotide; Opioid-Related Disorders; Propofol | 1998 |
Involvement of mu- and delta-opioid receptors in the ethanol-associated place preference in rats exposed to foot shock stress.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Ethanol; Exploratory Behavior; Foot; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Naloxone; Naltrexone; Narcotics; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1998 |
Orphanin FQ/nociceptin inhibits synaptic transmission and long-term potentiation in rat dentate gyrus through postsynaptic mechanisms.
Topics: Action Potentials; Animals; Dentate Gyrus; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; N-Methylaspartate; Naloxone; Naltrexone; Narcotic Antagonists; Neural Inhibition; Nociceptin; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Synapses; Synaptic Transmission; Tetrodotoxin | 1998 |
Sex differences in opioid and N-methyl-D-aspartate mediated non-opioid biting fly exposure induced analgesia in deer mice.
Topics: Amino Acids; Analgesia; Analysis of Variance; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Female; Houseflies; Insect Bites and Stings; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Peromyscus; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Sex Characteristics; Stress, Physiological | 1998 |
kappa-opioid regulation of neuronal activity in the rat supraoptic nucleus in vivo.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Cells, Cultured; Dendrites; Down-Regulation; Dynorphins; Electrophysiology; Female; Injections, Intravenous; Membrane Potentials; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Supraoptic Nucleus; Vasopressins | 1998 |
Nalmefene causes greater hypothalamic-pituitary-adrenal axis activation than naloxone in normal volunteers: implications for the treatment of alcoholism.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Alcoholism; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Infusions, Intravenous; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Pituitary-Adrenal System; Treatment Outcome | 1998 |
The effect of pentylenetetrazol kindling on synaptic mechanisms of interacting glutamatergic and opioid system in the hippocampus of rats.
Topics: Animals; Convulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Opioid; Seizures; Synapses | 1998 |
Opioid involvement in behavior modifications of mice infected with the parasitic nematode, Nippostrongylus brasiliensis.
Topics: Animals; Behavior, Animal; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Nippostrongylus; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu; Receptors, sigma; Strongylida Infections | 1998 |
Ameliorative effects of tachykinins on scopolamine-induced impairment of spontaneous alternation performance in mice.
Topics: Animals; Male; Mice; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin A; Peptide Fragments; Psychomotor Performance; Scopolamine; Substance P; Tachykinins | 1998 |
Time window for the contribution of the delta-opioid receptor to cardioprotection by ischemic preconditioning in the rat heart.
Topics: Animals; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Time Factors | 1998 |
Opioid efficacy in a C6 glioma cell line stably expressing the human kappa opioid receptor.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Rats; Receptors, Opioid, kappa; Stereoisomerism; Transfection; Tritium; Tumor Cells, Cultured | 1999 |
Heroin antinociception changed from mu to delta receptor in streptozotocin-treated mice.
Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heroin; Injections, Intraventricular; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu; Streptozocin; Time Factors | 1998 |
Effects of peptidase inhibitors on the enkephalin-induced anti-nociception in rats.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enkephalin, Methionine; Glycopeptides; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Peptides; Protease Inhibitors; Rats; Rats, Wistar | 1998 |
The involvement of opioidergic and noradrenergic mechanisms in nefopam antinociception.
Topics: Abdominal Pain; Acetic Acid; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Non-Narcotic; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nefopam; Pain Measurement; Receptors, Adrenergic; Receptors, Opioid | 1999 |
Opioid peptide pharmacology and immunocytochemistry in an animal model of self-sustaining status epilepticus.
Topics: Action Potentials; Analgesics; Analgesics, Opioid; Animals; Disease Models, Animal; Dynorphins; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Immunohistochemistry; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Opioid Peptides; Peptide Fragments; Perforant Pathway; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Status Epilepticus | 1999 |
Dynorphin A increases substance P release from trigeminal primary afferent C-fibers.
Topics: Animals; Animals, Newborn; Capsaicin; Dizocilpine Maleate; Dynorphins; Enkephalin, Leucine; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
Different roles of mu-, delta- and kappa-opioid receptors in ethanol-associated place preference in rats exposed to conditioned fear stress.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Psychological; Ethanol; Fear; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Psychological | 1999 |
[A molecular mechanism for supersensitization of adenylyl cyclase system in cloned opioid receptor-transfected cells following sustained opioid treatment].
Topics: Adenylyl Cyclases; Analgesics; Animals; Atropine; Benzeneacetamides; Carbachol; CHO Cells; Clone Cells; Cricetinae; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP Phosphohydrolases; Morphine; Muscarinic Agonists; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Transfection | 1998 |
Opioidergic modulation of voltage-activated K+ currents in magnocellular neurons of the supraoptic nucleus in rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ion Channel Gating; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Supraoptic Nucleus | 1999 |
Spinal blockade of opioid receptors prevents the analgesia produced by TENS in arthritic rats.
Topics: Animals; Arthritis; Behavior, Animal; Carrageenan; Injections, Intra-Articular; Kaolin; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Transcutaneous Electric Nerve Stimulation | 1999 |
Evaluation of hypothermia-induced analgesia and influence of opioid antagonists in leopard frogs (Rana pipiens).
Topics: Analgesia; Analgesics, Opioid; Animals; Evaluation Studies as Topic; Hypothermia, Induced; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rana pipiens | 1999 |
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain; Receptors, Opioid, mu; Time Factors | 1999 |
Direct preconditioning of cardiac myocytes via opioid receptors and KATP channels.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Anti-Arrhythmia Agents; Benzylidene Compounds; Cells, Cultured; Chick Embryo; Decanoic Acids; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Morphine; Muscle Fibers, Skeletal; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Potassium Channels; Receptors, Opioid | 1999 |
The discriminative stimulus effects of naloxone and naltrexone in morphine-treated rhesus monkeys: comparison of oral and subcutaneous administration.
Topics: Animals; Discrimination Learning; Female; Macaca mulatta; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics | 1999 |
Supersensitization of the adenylyl cyclase system in Chinese hamster ovary cells co-expressing cloned opioid receptors and Gz, a PTX-insensitive G protein.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Benzeneacetamides; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Activation; Female; GTP-Binding Protein alpha Subunits; Heterotrimeric GTP-Binding Proteins; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pertussis Toxin; Pyrrolidines; Receptors, Opioid; Virulence Factors, Bordetella | 1999 |
Naloxone blocks endomorphin-1 but not endomorphin-2 induced inhibition of tachykinergic contractions of guinea-pig isolated bronchus.
Topics: Analgesics, Opioid; Animals; Bronchi; Capsaicin; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin A; Oligopeptides; Receptors, Opioid, mu; Tachykinins | 1999 |
Ligands for opioid and sigma-receptors improve cardiac electrical stability in rat models of post-infarction cardiosclerosis and stress.
Topics: Animals; Anti-Arrhythmia Agents; beta-Endorphin; Disease Models, Animal; Dynorphins; Enkephalin, Leucine-2-Alanine; Heart; Immobilization; Ligands; Morphine; Myocardial Infarction; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Piperidines; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Stress, Physiological; Ventricular Fibrillation | 1999 |
Irreversible labelling of the opioid receptors by a melphalan-substituted [Met5]enkephalin-Arg-Phe derivative.
Topics: Affinity Labels; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Brain; Enkephalin, Methionine; Female; Guinea Pigs; Male; Melphalan; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Radioligand Assay; Rats; Receptors, Opioid | 1999 |
The bed nucleus of the stria terminalis. A target site for noradrenergic actions in opiate withdrawal.
Topics: Amygdala; Animals; Axonal Transport; Caudate Nucleus; Male; Microinjections; Morphine Dependence; Naloxone; Naltrexone; Neurons; Norepinephrine; Oxidopamine; Propranolol; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Thalamus; Tyrosine 3-Monooxygenase | 1999 |
Paradoxical effects of intracerebroventricular low-dose opioid antagonists in SHR with chronic pain.
Topics: Analgesia; Animals; Arteries; Blood Pressure; Body Temperature; Body Weight; Brain; Chronic Disease; Hypertension; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Quaternary Ammonium Compounds; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Modulation of emesis by fentanyl and opioid receptor antagonists in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Female; Fentanyl; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Receptors, Opioid; Shrews; Vomiting | 1999 |
Interactions between cholecystokinin and opioids in the isolated guinea-pig ileum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphinans; Muscle Contraction; Naloxone; Naltrexone; Oligopeptides; Opioid Peptides; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Receptors, Opioid; Sincalide; Substance Withdrawal Syndrome | 1999 |
Effects of diethylstilbestrol on mouse hippocampal evoked potentials in vitro.
Topics: Animals; Binding, Competitive; Dactinomycin; Diethylstilbestrol; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estrogens; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Pyramidal Cells; Receptors, Opioid; Receptors, Opioid, mu | 1999 |
Effects of opiate antagonist treatment on the alcohol deprivation effect in long-term ethanol-experienced rats.
Topics: Alcoholism; Animals; Ethanol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Self Administration | 1999 |
Endomorphin-1 and endomorphin-2, endogenous ligands for the mu-opioid receptor, inhibit electrical activity of rat rostral ventrolateral medulla neurons in vitro.
Topics: Animals; Electrophysiology; Enkephalin, Methionine; In Vitro Techniques; Ligands; Male; Medulla Oblongata; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Nociceptin; Oligopeptides; Opioid Peptides; Perfusion; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1999 |
Antinociceptive properties of FR140423 mediated through spinal delta-, but not mu- and kappa-, opioid receptors.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Binding, Competitive; Diarrhea; Injections, Intraventricular; Injections, Spinal; Male; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pyrazoles; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sulfoxides | 1999 |
Nalmefene. JF 1, nalmetrene, NIH 10365, ORF 11676, Arthrene, Cervene, Incystene, Revex.
Topics: Animals; Drug Overdose; Drugs, Investigational; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rabbits; Stroke | 1999 |
The delta 2-opioid receptor antagonist naltriben reduces motivated responding for ethanol.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous System Depressants; Conditioning, Operant; Ethanol; Female; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Reinforcement Schedule | 1999 |
Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons.
Topics: Analgesics, Opioid; Animals; Calcium; Cell Survival; Dizocilpine Maleate; Dynorphins; Embryo, Mammalian; Kynurenic Acid; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Neurotoxins; Peptide Fragments; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Valine | 1999 |
Is there a pharmacological basis for therapy with rapid opioid detoxification?
Topics: Anesthesia, General; Animals; Conscious Sedation; Cyclic AMP Response Element-Binding Protein; Heroin Dependence; Humans; Mice; Mice, Knockout; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Signal Transduction; Substance Withdrawal Syndrome; Treatment Outcome | 1999 |
Dynorphin A enhances mitogen-induced proliferative response and interleukin-2 production of rat splenocytes.
Topics: Analgesics, Opioid; Animals; Cells, Cultured; Concanavalin A; Dynorphins; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spleen | 1999 |
An interaction of opioids and galanin in dorsal horn of the spinal cord in mononeuropathic rats.
Topics: Animals; Galanin; Hindlimb; Injections, Spinal; Male; Mononeuropathies; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 2000 |
Analgesic effect of interferon-alpha via mu opioid receptor in the rat.
Topics: Analgesia; Animals; Antibodies, Monoclonal; Cell Line; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Leucine; Injections, Intraventricular; Interferon Type I; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Recombinant Proteins | 2000 |
Acute delta-opioid receptor activation induces CREB phosphorylation in NG108-15 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Analgesics, Opioid; Blotting, Western; Calmodulin; Cell Line; Cyclic AMP Response Element-Binding Protein; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; Humans; Isoquinolines; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Receptors, Opioid, delta; Time Factors | 2000 |
The antinociceptive effects of endomorphin-1 and endomorphin-2 in diabetic mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Activation of c-fos expression in hypothalamic nuclei by mu- and kappa-receptor agonists: correlation with catecholaminergic activity in the hypothalamic paraventricular nucleus.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Male; Methoxyhydroxyphenylglycol; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Norepinephrine; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Suprachiasmatic Nucleus; Supraoptic Nucleus | 2000 |
Inhibitory effect of intracerebroventricularly-administered [D-Arg(2), beta-Ala(4)]-dermorphin (1-4) on gastrointestinal transit.
Topics: Analgesics; Animals; Charcoal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Gastrointestinal Transit; Injections, Intraventricular; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides | 2000 |
Selective antagonism by naloxonazine of antinociception by Tyr-D-Arg-Phe-beta-Ala, a novel dermorphin analogue with high affinity at mu-opioid receptors.
Topics: Analgesics; Analgesics, Opioid; Animals; Drug Antagonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Pain Measurement; Receptors, Opioid, mu; Time Factors | 2000 |
Improvement by low doses of nociceptin on scopolamine-induced impairment of learning and/or memory.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Disease Models, Animal; Dizocilpine Maleate; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neuroprotective Agents; Nociceptin; Opioid Peptides; Psychomotor Performance; Rats; Scopolamine | 2000 |
Mercaptoacetate induces feeding through central opioid-mediated mechanisms in rats.
Topics: Animals; Antisense Elements (Genetics); Cloning, Molecular; Eating; Exons; Feeding Behavior; Injections, Intraperitoneal; Injections, Intraventricular; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereotyped Behavior; Thioglycolates | 2000 |
Naloxone antagonizes GABA(A)/benzodiazepine receptor function in rat corticohippocampal synaptoneurosomes.
Topics: Amobarbital; Animals; Cerebral Cortex; Chlorine; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Radioisotopes; Rats; Rats, Sprague-Dawley; Synaptosomes | 2000 |
Functional evidence that gastroprotection can be induced by activation of central alpha(2B)-adrenoceptor subtypes in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Clonidine; Enkephalin, Leucine-2-Alanine; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2 | 2000 |
Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses.
Topics: Animals; Anxiety; Binding Sites; Darkness; Depression; Electroshock; Female; Gene Deletion; Light; Male; Mice; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Threshold; Phenotype; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Characteristics; Swimming | 2000 |
The effects of highly selective opioid receptor antagonists on the release of arginine vasotocin induced by hyperosmotic stimulation and angiotensin II injection.
Topics: Angiotensin II; Animals; Chickens; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saline Solution, Hypertonic; Vasotocin | 2000 |
Selective opioid receptor agonist and antagonist displacement of [3H]naloxone binding in amphibian brain.
Topics: Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Radioligand Assay; Rana pipiens; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium | 2000 |
Altered opioid-mediated control of the spinal release of dynorphin and met-enkephalin in polyarthritic rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Animals; Arthritis; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Iodine Radioisotopes; Ligands; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 2000 |
Receptor selectivity of Met-enkephalin-Arg6-Phe7, an endogenous opioid peptide, in cerebral cortex of human and rat.
Topics: Adult; Animals; Benzeneacetamides; Benzomorphans; Binding Sites; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Ethylketocyclazocine; Female; Humans; Male; Naloxone; Naltrexone; Norepinephrine; Oligopeptides; Peptide Fragments; Peptides; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2000 |
Managing constipation that's opioid-induced.
Topics: Administration, Oral; Adult; Analgesics, Opioid; Breast Neoplasms; Chemistry, Pharmaceutical; Constipation; Female; Humans; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Quaternary Ammonium Compounds | 2000 |
Calmodulin regulation of basal and agonist-stimulated G protein coupling by the mu-opioid receptor (OP(3)) in morphine-pretreated cell.
Topics: Amino Acid Substitution; Animals; Calmodulin; Cell Line; Cell Membrane; Chickens; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kidney; Kinetics; Morphine; Mutagenesis, Site-Directed; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Recombinant Proteins; Transfection | 2000 |
Involvement of central opioid systems in human interferon-alpha induced immobility in the mouse forced swimming test.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Interferon-alpha; Interferon-beta; Interferon-gamma; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Swimming; Time Factors | 2000 |
Antinociceptive effects of Nigella sativa oil and its major component, thymoquinone, in mice.
Topics: Analgesics, Non-Narcotic; Animals; Benzoquinones; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Naltrexone; Plant Oils; Plants, Medicinal | 2000 |
Morphine stimulates mesangial cell TNF-alpha and nitrite production.
Topics: Animals; Antibodies, Monoclonal; Cell Line, Transformed; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Heroin Dependence; HIV Envelope Protein gp120; HIV Infections; Lipopolysaccharides; Macrophages; Mice; Morphine; Muscle, Smooth, Vascular; Naloxone; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitrites; Tumor Necrosis Factor-alpha | 2000 |
Differential involvement of opioid receptors in stress-induced antinociception caused by repeated exposure to forced walking stress in mice.
Topics: Animals; Formaldehyde; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid; Stress, Physiological; Walking | 2000 |
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
Topics: Amino Acid Substitution; Animals; Benzamides; Benzomorphans; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes | 2000 |
Morphine discriminative control is mediated by the mu opioid receptor: assessment of delta opioid substitution and antagonism.
Topics: Animals; Benzamides; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Generalization, Response; Methadone; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Piperazines; Rats; Rats, Long-Evans; Receptors, Opioid, delta; Receptors, Opioid, mu | 2000 |
Synthesis and antinociceptive activity of pyrrolidinylnaphthalenes.
Topics: Analgesics; Animals; Drug Design; Male; Mice; Molecular Structure; Motor Activity; Naloxone; Naltrexone; Naphthalenes; Narcotic Antagonists; Pyrrolidines; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2000 |
Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heroin; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Receptors, Opioid, mu | 2000 |
Kinetics and inhibition of the formation of 6beta-naltrexol from naltrexone in human liver cytosol.
Topics: Adult; Aged; Analgesics, Opioid; Benzodiazepines; Chromatography, High Pressure Liquid; Corticosterone; Cytosol; Dihydrotestosterone; Enzyme Inhibitors; Humans; Kinetics; Liver; Microsomes, Liver; Middle Aged; Naloxone; Naltrexone; Oxidoreductases; Oxycodone; Reproducibility of Results; Substrate Specificity; Testosterone; Vitamin K | 2000 |
Dose- and time-dependent bimodal effects of kappa-opioid agonists on locomotor activity in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetamides; Animals; Benzomorphans; Dose-Response Relationship, Drug; Isothiocyanates; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid, kappa; Time Factors | 2000 |
Morphine inhibits human microglial cell production of, and migration towards, RANTES.
Topics: Brain; Calcium; Cells, Cultured; Chemokine CCL5; Chemotaxis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fetus; Humans; Interleukin-1; Lipopolysaccharides; Microglia; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Recombinant Proteins | 2000 |
Acoustic startle and open-field behavior in mice bred for magnitude of swim analgesia.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Brain; Female; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid; Reflex, Startle; Sex Factors; Spatial Behavior; Swimming | 2000 |
Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, mu; Somatostatin | 2000 |
Inhibition of passive cutaneous anaphylaxis-associated scratching behavior by mu-opioid receptor antagonists in ICR mice.
Topics: Animals; Behavior, Animal; Capillary Permeability; Female; Histamine; Humans; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Pruritus; Receptors, Opioid, mu | 2000 |
Injections of an opioid antagonist into the locus coeruleus and periaqueductal gray but not the amygdala precipitates morphine withdrawal in the 7-day-old rat.
Topics: Age Factors; Amygdala; Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Locus Coeruleus; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid-Related Disorders; Periaqueductal Gray; Quaternary Ammonium Compounds; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome | 2001 |
Suppression of ethanol responding by centrally administered CTOP and naltrindole in AA and Wistar rats.
Topics: Alcohol Drinking; Amygdala; Animals; Central Nervous System Depressants; Conditioning, Operant; Ethanol; Genotype; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Somatostatin | 2001 |
[Evolution and update of detoxification techniques for opiate addicts].
Topics: Animals; Buprenorphine; Humans; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome | 2000 |
Role of PAG in the antinociception evoked from the medial or central amygdala in rats.
Topics: Adrenergic beta-Antagonists; Amygdala; Anesthetics, Local; Animals; Atropine; Electric Stimulation; Ganglionic Blockers; Lidocaine; Male; Mecamylamine; Methysergide; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Threshold; Parasympatholytics; Periaqueductal Gray; Propranolol; Rats; Rats, Wistar; Serotonin Antagonists | 2001 |
Pharmacological effects of naltriben as a ligand for opioid mu and kappa receptors in rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Ligands; Male; Naloxone; Naltrexone; Narcotic Antagonists; Norepinephrine; Peptide Fragments; Peptides; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Tritium | 2001 |
Blockade of delta opioid receptors in the ventrolateral periaqueductal gray region inhibits the fall in arterial pressure evoked by hemorrhage.
Topics: Animals; beta-Endorphin; Blood Pressure; Hemorrhage; Homocysteine; Male; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 2001 |
TRK-820, a selective kappa-opioid agonist, produces potent antinociception in cynomolgus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Macaca fascicularis; Morphinans; Morphine; Naloxone; Naltrexone; Pain Measurement; Pentazocine; Pentobarbital; Receptors, Opioid, kappa; Spiro Compounds | 2001 |
Endogenous opioids suppress activation of nociceptors by sub-nanomolar nicotine.
Topics: Adrenal Medulla; Analysis of Variance; Animals; Animals, Newborn; Bradykinin; Capsaicin; Dose-Response Relationship, Drug; Hexamethonium; Inflammation; Knee Joint; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Nicotine; Nociceptors; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid; Sciatic Nerve; Time Factors | 2001 |
Enhancement of the effects of a complete inhibitor of enkephalin-catabolizing enzymes, RB 101, by a cholecystokinin-B receptor antagonist in diabetic rats.
Topics: Aminopeptidases; Animals; Diabetes Mellitus, Experimental; Disulfides; Drug Synergism; Indoles; Male; Meglumine; Naloxone; Naltrexone; Neprilysin; Pain; Pain Measurement; Phenylalanine; Pressure; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Time Factors; Vocalization, Animal; Weight Loss | 2001 |
Pharmacological characterization of the dermorphin analog [Dmt(1)]DALDA, a highly potent and selective mu-opioid peptide.
Topics: Analgesics; Animals; Drug Tolerance; Humans; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Opioid Peptides; Pain Measurement; Receptors, Opioid, mu; Time Factors | 2001 |
Stimulation of guanosine-5'-o-(3-[35S]thio)triphosphate binding in digitonin-permeabilized C6 rat glioma cells: evidence for an organized association of mu-opioid receptors and G protein.
Topics: Analgesics, Opioid; Animals; Digitonin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Tumor Cells, Cultured | 2001 |
Blockade of opioid receptors in rostral ventral medulla prevents antihyperalgesia produced by transcutaneous electrical nerve stimulation (TENS).
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hot Temperature; Hyperalgesia; Male; Medulla Oblongata; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Transcutaneous Electric Nerve Stimulation | 2001 |
Chronic exposure to mu-opioid agonists produces constitutive activation of mu-opioid receptors in direct proportion to the efficacy of the agonist used for pretreatment.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics, Opioid; Animals; Binding Sites; Cells, Cultured; Cyclic AMP; Down-Regulation; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, mu; Sulfur Radioisotopes; Transfection; Virulence Factors, Bordetella | 2001 |
Inverse agonists and neutral antagonists at mu opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence.
Topics: Analgesics, Opioid; Animals; Benzylidene Compounds; Cell Line; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kidney; Magnesium; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Receptors, Opioid, mu; Signal Transduction; Substance Withdrawal Syndrome; Sulfur Radioisotopes; Transfection; Tritium | 2001 |
Analgesic and antiinflammatory effects of two novel kappa-opioid peptides.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Dose-Response Relationship, Drug; Inflammation; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Threshold; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa | 2001 |
Signal transduction of opioid-induced cardioprotection in ischemia-reperfusion.
Topics: Animals; ATP-Binding Cassette Transporters; Benzamides; Benzylidene Compounds; Cell Survival; Chick Embryo; Decanoic Acids; Free Radicals; Hydroxy Acids; KATP Channels; Myocardial Reperfusion Injury; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxidative Stress; Piperazines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Opioid, delta; Signal Transduction | 2001 |
Opioid and GABA receptors involved in mediation and modulation of tonic and stimulus-evoked inhibition of a spinal reflex in the decerebrated and spinalized rabbit.
Topics: Animals; Bicuculline; Conditioning, Classical; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Methionine; Female; GABA Antagonists; Male; Muscle Tonus; Naloxone; Naltrexone; Narcotic Antagonists; Organophosphorus Compounds; Rabbits; Receptors, GABA; Receptors, Opioid; Receptors, Opioid, mu; Receptors, sigma; Reflex | 2001 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors | 2001 |
Naltrexone potentiates anti-HIV-1 activity of antiretroviral drugs in CD4+ lymphocyte cultures.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Drug Combinations; Drug Synergism; HIV-1; Humans; Indinavir; Naloxone; Naltrexone; Narcotic Antagonists; Zidovudine | 2001 |
Naloxone fails to produce conditioned place aversion in mu-opioid receptor knock-out mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Avoidance Learning; Brain; Conditioning, Psychological; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Opioid Peptides; Phenotype; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Synaptic Transmission | 2001 |
The effect of the leucopyrokinin analogue: [2-8]-leucopyrokinin on central opioid receptors in rats.
Topics: Analgesia; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tail; Time Factors | 2001 |
[The combined use of scopolamine, naltrexone and naloxone as a rapid, safe and effective detoxification treatment for heroin addicts].
Topics: Adult; Drug Therapy, Combination; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Scopolamine | 1999 |
Endomorphin-1 improves scopolamine-induced impairment of short-term memory via mu1-opioid receptor in mice.
Topics: Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Receptors, Opioid, mu; Scopolamine | 2001 |
Morphine upregulates kappa-opioid receptors of human lymphocytes.
Topics: Animals; Cell Line; Humans; Hybrid Cells; Immunosuppressive Agents; Lymphocytes; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2001 |
Opioid and cholecystokinin antagonists alleviate gastric inhibition of food intake by premeal loads of casein in meal-fed rats.
Topics: Amino Acids; Animals; Blood Glucose; Caseins; Cholecystokinin; Diet; Dietary Proteins; Eating; Feces; Insulin; Insulin-Like Growth Factor I; Intestines; Male; Naloxone; Naltrexone; Narcotic Antagonists; Proglumide; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Soybean Proteins; Stomach | 2001 |
Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited by electrical and chemical stimulation of the deep layers of the superior colliculus and dorsal
Topics: Aggression; Animals; Bicuculline; Electric Stimulation; Fear; GABA Antagonists; Immunohistochemistry; Male; Mesencephalon; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA; Receptors, Opioid; Stimulation, Chemical; Superior Colliculi | 2002 |
Immunomodulation by opioid peptidomimetic compound.
Topics: Animals; Cells, Cultured; Humans; Leukocytes, Mononuclear; Macrophages; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neuroimmunomodulation; Nitric Oxide; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Necrosis Factor-alpha | 2001 |
Comparison of the peripheral and central effects of the opioid agonists loperamide and morphine in the formalin test in rats.
Topics: Analgesics, Opioid; Animals; Antidiarrheals; Cisterna Magna; Dose-Response Relationship, Drug; Formaldehyde; Injections; Injections, Subcutaneous; Loperamide; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2002 |
[Role of delta opioid receptors and their ligands in the development of adaptive heart protection against arrhythmogenesis].
Topics: Adaptation, Physiological; Animals; Arrhythmias, Cardiac; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Ligands; Male; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Tetrahydroisoquinolines; Thiorphan | 2001 |
Itch-associated response induced by experimental dry skin in mice.
Topics: Animals; Behavior, Animal; Blood-Air Barrier; Male; Mast Cells; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pruritus; Skin; Skin Diseases; Water Loss, Insensible | 2002 |
Motivational effects mu- and kappa-opioid agonists following acute and chronic restraint stress: involvement of dopamine D(1) and D(2) receptors.
Topics: Acute Disease; Animals; Behavior, Animal; Benzomorphans; Chronic Disease; Conditioning, Operant; Injections, Intraventricular; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Psychological | 2002 |
In vivo and in vitro potency studies of 6beta-naltrexol, the major human metabolite of naltrexone.
Topics: Animals; Culture Techniques; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guinea Pigs; Ileum; Isometric Contraction; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain Threshold; Receptors, Opioid, mu | 2002 |
Anti-nociceptive effect of neuropeptide Y in the nucleus accumbens of rats: an involvement of opioid receptors in the effect.
Topics: Animals; Catheterization; Dose-Response Relationship, Drug; Hot Temperature; Male; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Neuropeptide Y; Nucleus Accumbens; Pain Measurement; Peptide Fragments; Physical Stimulation; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Receptors, Opioid | 2002 |
Sevoflurane suppresses noxious stimulus-evoked expression of Fos-like immunoreactivity in the rat spinal cord via activation of endogenous opioid systems.
Topics: Analgesics; Anesthetics, Inhalation; Animals; Formaldehyde; Male; Methyl Ethers; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sevoflurane; Spinal Cord | 2002 |
Differential antagonism of endomorphin-1 and endomorphin-2 supraspinal antinociception by naloxonazine and 3-methylnaltrexone.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Quaternary Ammonium Compounds; Reflex; Time Factors | 2002 |
Blockade of nigral and pallidal opioid receptors suppresses vacuous chewing movements in a rodent model of tardive dyskinesia.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Dyskinesia, Drug-Induced; Fluphenazine; Globus Pallidus; Male; Mastication; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Substantia Nigra | 2002 |
Involvement of endogenous opioid systems in nociceptin-induced spinal antinociception in rats.
Topics: Animals; Endorphins; Hindlimb; Hot Temperature; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptors; Opioid Peptides; Pain; Pain Measurement; Peptide Fragments; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord | 2002 |
Possible involvement of mu1-opioid receptors in the fentanyl- or morphine-induced antinociception at supraspinal and spinal sites.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, mu; Spinal Cord | 2002 |
Effects of opioid antagonists on unconditioned and conditioned hyperactivity to morphine.
Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Hyperkinesis; Male; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2002 |
Chronic agonist treatment converts antagonists into inverse agonists at delta-opioid receptors.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cell Line; Cell Membrane; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Receptors, Opioid, delta; Receptors, Opioid, mu | 2002 |
Lack of the nociceptin receptor does not affect acute or chronic nociception in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Male; Mice; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Pain; Receptors, Opioid; Time Factors; Vas Deferens | 2002 |
Different effects of methionine-enkephalin on paw edema in two inbred rat strains.
Topics: Animals; Dexamethasone; Dose-Response Relationship, Drug; Edema; Enkephalin, Methionine; Glucocorticoids; Inflammation; Kinetics; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Species Specificity; Time Factors | 2002 |
Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Cues; Discrimination, Psychological; Ethanol; Extinction, Psychological; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration | 2002 |
Quantitative stoichiometry of G-proteins activated by mu-opioid receptors in postmortem human brain.
Topics: Alkylation; Analgesics, Opioid; Baclofen; Binding, Competitive; Brain Chemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Ethylmaleimide; GABA Agonists; GTP-Binding Protein Regulators; GTP-Binding Proteins; Humans; In Vitro Techniques; Kinetics; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Signal Transduction | 2002 |
Focal kappa-opioid receptor-mediated dependence and withdrawal in the nucleus paragigantocellularis.
Topics: Animals; Basal Ganglia; Butorphanol; Diffusion; Electric Stimulation; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Stereotaxic Techniques; Stereotyped Behavior; Substance Withdrawal Syndrome | 2002 |
Functional interactions between delta- and mu-opioid receptors in rat thermoregulation.
Topics: Animals; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Opioid, delta; Receptors, Opioid, mu | 2003 |
Effects of beta-funaltrexamine and naloxonazine on single-trial morphine-conditioned place preference and locomotor activity.
Topics: Animals; Conditioning, Psychological; Male; Morphine; Motor Activity; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2003 |
Opioid receptor antagonists modulate Ca2+-activated K+ channels in mesenteric arterial smooth muscle cells of rats in hemorrhagic shock.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Down-Regulation; Electrophysiology; Kinetics; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naloxone; Naltrexone; Narcotic Antagonists; Potassium Channels; Rats; Rats, Wistar; Shock, Hemorrhagic | 2003 |
Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.
Topics: Analgesics, Opioid; Animals; Antibodies, Blocking; Cloning, Molecular; Dynorphins; Endorphins; Enkephalin, Methionine; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Radioligand Assay; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey.
Topics: Animals; Benzeneacetamides; Conditioning, Operant; Dextrorphan; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Levorphanol; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Receptors, Opioid; Saimiri; Substance Withdrawal Syndrome | 2003 |
Behavioral and neuroendocrine actions of the Met-enkephalin-related peptide MERF.
Topics: Analysis of Variance; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Dopamine; Enkephalin, Methionine; Exploratory Behavior; Haloperidol; Hormone Antagonists; Hypothalamo-Hypophyseal System; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neostriatum; Organ Culture Techniques; Peptide Fragments; Pituitary-Adrenal System | 2003 |
The antitussive effects of endomorphin-1 and endomorphin-2 in mice.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
Opiate withdrawal induces Narp in the extended amygdala.
Topics: Amygdala; Analgesics; Animals; C-Reactive Protein; Cell Count; Clonidine; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Septal Nuclei; Substance Withdrawal Syndrome | 2003 |
Chemical anesthesia of northern sea otters (Enhydra lutris): results of past field studies.
Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Azaperone; Body Temperature; Diazepam; Female; Fentanyl; Heart Rate; Hypnotics and Sedatives; Immobilization; Logistic Models; Male; Naloxone; Naltrexone; Narcotic Antagonists; Otters; Respiration; Seizures; Time Factors; Tremor | 2001 |
Neuroprotection of naloxone against ischemic injury in rats: role of mu receptor antagonism.
Topics: Animals; Carotid Artery, Common; Cerebral Infarction; Coronary Disease; Functional Laterality; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Time Factors | 2003 |
Effects of U50,488H on transient outward and ultra-rapid delayed rectifier K+ currents in young human atrial myocytes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adolescent; Child; Child, Preschool; Delayed Rectifier Potassium Channels; Female; Heart Atria; Humans; Infant; Male; Myocytes, Cardiac; Naloxone; Naltrexone; Narcotic Antagonists; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Tandem Pore Domain; Potassium Channels, Voltage-Gated; Receptors, Opioid, kappa | 2003 |
[Dual regulation by delta opioid receptor agonists on the delayed rectified potassium channels in NG108-15 cells].
Topics: Animals; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Glioma; Hybrid Cells; Mice; Naloxone; Naltrexone; Neuroblastoma; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Opioid, delta; Tumor Cells, Cultured | 2003 |
Involvement of oxytocin in spinal antinociception in rats with inflammation.
Topics: Analgesics; Animals; Carrageenan; Hot Temperature; Inflammation; Injections, Spinal; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxytocin; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Vasotocin | 2003 |
kappa-Opioid withdrawal in Planaria.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adaptation, Physiological; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Osmolar Concentration; Planarians; Reaction Time; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 2003 |
Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors.
Topics: Animals; Binding, Competitive; Blotting, Western; Cell Line; Cloning, Molecular; Colforsin; Copper Sulfate; Cyclic AMP; Diprenorphine; DNA, Complementary; Drosophila; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression; Genetic Vectors; Green Fluorescent Proteins; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Luminescent Proteins; Metallothionein; Microscopy, Confocal; Morphine; Naloxone; Naltrexone; Oligopeptides; Opioid Peptides; Pertussis Toxin; Polymerase Chain Reaction; Protein Binding; Receptors, G-Protein-Coupled; Receptors, Opioid, mu; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Thermodynamics | 2003 |
An opioid basis for early-phase isoflurane-induced hypotension in rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Antibodies, Blocking; beta-Endorphin; Blood Pressure; Endorphins; Enkephalin, Methionine; Hot Temperature; Hypotension; Injections, Intraventricular; Isoflurane; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Urethane | 2003 |
Effects of endomorphin on substantia gelatinosa neurons in rat spinal cord slices.
Topics: Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Postsynaptic Potentials; Female; Male; Membrane Potentials; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Substantia Gelatinosa; Tetrodotoxin; Time Factors | 2003 |
Dynorphinergic mechanism mediating endomorphin-2-induced antianalgesia in the mouse spinal cord.
Topics: Analgesics, Opioid; Animals; Antibodies, Blocking; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dynorphins; Excitatory Amino Acid Antagonists; Injections, Spinal; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Reaction Time; Receptors, Opioid; Spinal Cord | 2003 |
Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzazepines; Dopamine; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Endorphins; Female; Levodopa; Macaca fascicularis; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission | 2003 |
Effect of opioid receptor ligands on the mu-S196A knock-in and mu knockout mouse vas deferens.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine-2-Alanine; In Vitro Techniques; Ligands; Male; Mice; Mice, Knockout; Mice, Transgenic; Morphine; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Vas Deferens | 2003 |
Delta opioid receptors are involved in morphine-induced inhibition of luteinizing hormone releasing hormone in SK-N-SH cells.
Topics: Analgesics, Opioid; Cell Line, Tumor; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormone; Humans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid, delta; Somatostatin | 2003 |
Reassessment of buprenorphine in conditioned place preference: temporal and pharmacological considerations.
Topics: Animals; Buprenorphine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Nociceptin Receptor; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa; Time Factors | 2004 |
Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of mu(1)- and kappa-opioid receptor blockade on escape behavior induced by electrical stimulation of the inferior colliculus.
Topics: Animals; Biotin; Dextrans; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Fear; Inferior Colliculi; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Periaqueductal Gray; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
Mechanisms of the effects of adrenocorticotropic hormone on pain sensitivity in rats.
Topics: Adrenocorticotropic Hormone; Animals; Drug Interactions; Hydrocortisone; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Combined low dose treatment with opioid and cannabinoid receptor antagonists synergistically reduces the motivation to consume alcohol in rats.
Topics: Alcohol Drinking; Animals; Cannabinoids; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Male; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Rimonabant | 2004 |
Radial arm maze performance of rats following repeated low level microwave radiation exposure.
Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Resistance; Male; Maze Learning; Microwaves; Naloxone; Naltrexone; Physostigmine; Psychotropic Drugs; Radiation Dosage; Radiation Tolerance; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Task Performance and Analysis; Whole-Body Irradiation | 2004 |
Differential antinociceptive effects of L-arginine and 3-morpholinosydoimine.
Topics: Analgesics; Animals; Arginine; Dose-Response Relationship, Drug; Dynorphins; Injections, Intraventricular; Male; Mice; Molsidomine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement | 2003 |
Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus.
Topics: Analgesics, Opioid; Animals; Electric Stimulation; Female; Hot Temperature; Injections, Spinal; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Pathways; Nociceptors; Raphe Nuclei; Rats; Rats, Sprague-Dawley | 2004 |
Social learning about ethanol in preweanling rats: role of endogenous opioids.
Topics: Animals; Animals, Newborn; Behavior, Animal; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Ethanol; Learning; Naloxone; Naltrexone; Narcotic Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Social Behavior; Weaning | 2004 |
Nonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord.
Topics: Analgesia; Animals; beta-Endorphin; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Male; Mice; Morphine; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Substance P | 2004 |
Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation.
Topics: Cell Line; Gene Expression; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Sensitivity and Specificity; Smoking Cessation; Structure-Activity Relationship; Time Factors; Up-Regulation | 2004 |
Supraspinal and spinal cord opioid receptors are responsible for antinociception following intrathecal morphine injections.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Models, Animal; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Pain Threshold; Random Allocation; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid; Spinal Cord; Tail | 2004 |
Functional opioid pathways are necessary for hypocretin-1 (orexin-A)-induced feeding.
Topics: Animals; Appetite Regulation; Carrier Proteins; Eating; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Naloxone; Naltrexone; Neuropeptides; Orexins; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley | 2004 |
Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Tetrodotoxin; Time Factors | 2004 |
Opioid growth factor (OGF) inhibits anchorage-independent growth in human cancer cells.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cell Adhesion; Cell Division; Colonic Neoplasms; Colony-Forming Units Assay; Enkephalin, Methionine; Head and Neck Neoplasms; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Pancreatic Neoplasms; Receptors, Opioid; Transplantation, Heterologous; Tumor Cells, Cultured | 2004 |
Supraspinal anti-allodynic and rewarding effects of endomorphins in rats.
Topics: Analgesics, Opioid; Animals; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Compression Syndromes; Oligopeptides; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley | 2004 |
Involvement of opioid receptors in the oxytocin-induced antinociception in the central nervous system of rats.
Topics: Animals; Central Nervous System; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2004 |
The antinociceptive effect of Delta9-tetrahydrocannabinol in the arthritic rat.
Topics: Animals; Arthritis, Experimental; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Dronabinol; Dynorphins; Enkephalin, Leucine; Enkephalin, Methionine; Freund's Adjuvant; Injections, Intradermal; Injections, Intraperitoneal; Male; Morphine; Mycobacterium; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid; Rimonabant | 2004 |
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats.
Topics: Acamprosate; Animals; Choice Behavior; Ethanol; Male; Memantine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taurine | 2004 |
Plasma concentrations during naltrexone implant treatment of opiate-dependent patients.
Topics: Adult; Drug Implants; Female; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders | 2004 |
A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu | 2005 |
Antagonist efficacy in MORS196L mutant is affected by the interaction between transmembrane domains of the opioid receptor.
Topics: Animals; Cyclic AMP; Diprenorphine; Electrophysiology; Mutagenesis, Site-Directed; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Oocytes; Patch-Clamp Techniques; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Fusion Proteins; RNA, Complementary; Xenopus | 2005 |
Opioid-mediated pain sensitivity in mice bred for high voluntary wheel running.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Breeding; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Pain Threshold; Reaction Time; Running; Selection, Genetic; Species Specificity; Time Factors | 2004 |
The development of tolerance to locomotor effects of morphine and the effect of various opioid receptor antagonists in rats chronically treated with morphine.
Topics: Animals; Behavior, Animal; Drug Interactions; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar; Time Factors | 2005 |
Comment on "Radial arm maze performance of rats following repeated low level microwave radiation exposure".
Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Resistance; Male; Maze Learning; Microwaves; Naloxone; Naltrexone; Physostigmine; Psychotropic Drugs; Radiation Dosage; Radiation Tolerance; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Task Performance and Analysis; Whole-Body Irradiation | 2005 |
Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouse.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hot Temperature; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Nociceptors; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu; Tail; Time Factors | 2005 |
In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice.
Topics: Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders | 2005 |
Effect of the blockade of mu1-opioid and 5HT2A-serotonergic/alpha1-noradrenergic receptors on sweet-substance-induced analgesia.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesia; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Methysergide; Naloxone; Naltrexone; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Serotonin Antagonists; Sucrose; Taste | 2005 |
Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Cholecystokinin; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Receptor, Adenosine A1; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Theophylline | 2005 |
Opioid antagonists differ according to negative intrinsic efficacy in a mouse model of acute dependence.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Diprenorphine; Dose-Response Relationship, Drug; Male; Mice; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome; Tremor | 2005 |
Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin | 2005 |
Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; Emotions; Enkephalins; Enzyme Inhibitors; Exploratory Behavior; Freezing Reaction, Cataleptic; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Phenylalanine; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu; Swimming; Time Factors | 2005 |
Attenuation of post-ischemia reperfusion injury by thaliporphine and morphine in rat hearts.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Antioxidants; Aporphines; Creatine Kinase; Dose-Response Relationship, Drug; Heart; Male; Mitochondria; Morphine; Myocardial Ischemia; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Peroxidase; Plant Extracts; Potassium; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Risk; Time Factors | 2005 |
Opioid receptors modulate recovery from consummatory successive negative contrast.
Topics: Animals; Conditioning, Operant; Consummatory Behavior; Inhibition, Psychological; Male; Naloxone; Naltrexone; Narcotic Antagonists; Random Allocation; Rats; Rats, Long-Evans; Receptors, Opioid; Reinforcement, Psychology | 2005 |
Letter to the editor concerning "Radial arm maze performance of rats following repeated low-level microwave radiation exposure" by Cobb et al. [BEMS, 2004, 25:49-57] and "letter to the editor" by Lai [BEMS, 2005, 26:81].
Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Resistance; Male; Maze Learning; Microwaves; Naloxone; Naltrexone; Physostigmine; Psychotropic Drugs; Radiation Dosage; Radiation Tolerance; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Task Performance and Analysis; Whole-Body Irradiation | 2005 |
Letter to the editor concerning Lai's letter on "Radial arm maze performance of rats following repeated low level microwave radiation exposure" [Bioelectromagnetics 25:49-57 (2004)].
Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Resistance; Male; Maze Learning; Microwaves; Naloxone; Naltrexone; Physostigmine; Psychotropic Drugs; Radiation Dosage; Radiation Tolerance; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Task Performance and Analysis; Whole-Body Irradiation | 2005 |
Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa.
Topics: Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Subcutaneous; Male; Mice; Mitragyna; Models, Molecular; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Reaction Time; Secologanin Tryptamine Alkaloids; Substance Withdrawal Syndrome; Thailand | 2005 |
The role of opioid receptor subtypes in the development of behavioral sensitization to ethanol.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Somatostatin; Time Factors | 2006 |
Coordinated and spatial upregulation of arc in striatonigral neurons correlates with L-dopa-induced behavioral sensitization in dyskinetic rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic Agents; AIDS-Related Complex; Amphetamine; Analgesics, Non-Narcotic; Animals; Antiparkinson Agents; Behavior, Animal; Carrier Proteins; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Functional Laterality; Homer Scaffolding Proteins; Immunohistochemistry; In Situ Hybridization; Levodopa; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oxidopamine; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation | 2005 |
Kappa-opioid receptor-mediated effects of the plant-derived hallucinogen, salvinorin A, on inverted screen performance in the mouse.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzeneacetamides; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Psychotropic Drugs; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil | 2005 |
Localization of opioid receptor antagonist [3H]-LY255582 binding sites in mouse brain: comparison with the distribution of mu, delta and kappa binding sites.
Topics: Animals; Autoradiography; Binding Sites; Brain; Cyclohexanes; Mice; Mice, Knockout; Molecular Structure; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tritium | 2005 |
Effects of systemic administration of beta-casomorphin-5 on learning and memory in mice.
Topics: Analgesics; Animals; Avoidance Learning; Cattle; Dose-Response Relationship, Drug; Endorphins; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Memory; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid, mu; Scopolamine | 2006 |
mu- but not delta- and kappa-opioid receptor mediates the nucleus submedius interferon-alpha-evoked antinociception in the rat.
Topics: Animals; Escape Reaction; Interferon-alpha; Male; Mediodorsal Thalamic Nucleus; Microinjections; Naloxone; Naltrexone; Pain; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2006 |
Modulation of Delta(9)-THC-induced increase of cortical and hippocampal acetylcholine release by micro opioid and D(1) dopamine receptors.
Topics: Acetylcholine; Animals; Behavior, Animal; Benzazepines; Dopamine Antagonists; Dronabinol; Drug Interactions; Hippocampus; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Opioid, mu; Time Factors | 2006 |
Inhibition of morphine tolerance by processed Aconiti tuber is mediated by kappa-opioid receptors.
Topics: Aconitum; Analgesics, Opioid; Animals; Cinnamates; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Drugs, Chinese Herbal; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Plant Tubers; Receptors, Opioid, kappa; Time Factors | 2006 |
Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.
Topics: Allosteric Regulation; Analgesics, Opioid; Animals; Cannabidiol; Cerebral Cortex; Dose-Response Relationship, Drug; Dronabinol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 2006 |
Involvements of mu- and kappa-opioid receptors in morphine-induced antinociception in the nucleus accumbens of rats.
Topics: Analgesics, Opioid; Animals; Male; Morphine; Naloxone; Naltrexone; Nucleus Accumbens; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2006 |
The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine.
Topics: Analgesics; Animals; Antidepressive Agents; Desipramine; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Trimipramine | 2006 |
Role of kappa- and delta-opioid receptors in the antinociceptive effect of oxytocin in formalin-induced pain response in mice.
Topics: Analgesics; Animals; Behavior; Calcium Channel Blockers; Dose-Response Relationship, Drug; Formaldehyde; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Nimodipine; Oxytocin; Pain; Random Allocation; Receptors, Opioid, delta; Receptors, Opioid, kappa | 2006 |
Potent in vivo antinociception and opioid receptor preference of the novel analogue [Dmt1]endomorphin-1.
Topics: Analgesia; Animals; Brain; Guinea Pigs; Ileum; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Tail; Vas Deferens | 2006 |
Atypical anxiolytic-like response to naloxone in benzodiazepine-resistant 129S2/SvHsd mice: role of opioid receptor subtypes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Drug Resistance; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naloxone; Naltrexone; Opioid Peptides; Receptors, Opioid; Species Specificity | 2006 |
The effects of endomorphins and diprotin A on striatal dopamine release induced by electrical stimulation-an in vitro superfusion study in rats.
Topics: Animals; Corpus Striatum; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dopamine; Electric Stimulation; Infusion Pumps; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Oligopeptides; Organ Culture Techniques; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Wistar; Substantia Nigra; Synaptic Transmission | 2006 |
Expression and localization of delta-, kappa-, and mu-opioid receptors in human spermatozoa and implications for sperm motility.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adult; Analgesics, Opioid; Humans; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sperm Motility; Spermatozoa; Tissue Distribution | 2006 |
Involvement of opioid receptors in oxytocin-induced antinociception in the nucleus accumbens of rats.
Topics: Analgesics; Animals; Hot Temperature; Male; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oxytocin; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2007 |
Activators of potassium M currents have anticonvulsant actions in two rat models of encephalitis.
Topics: Aminopyridines; Analgesics; Animals; Anticonvulsants; Borna Disease; Encephalitis, Viral; Herpes Simplex; Herpesvirus 1, Human; Male; Naloxone; Naltrexone; Narcotic Antagonists; Potassium; Rats; Rats, Inbred Lew; Receptors, Opioid, delta; Seizures; Substance Withdrawal Syndrome | 2007 |
Negative inotropic and chronotropic effects of delta-opioid receptor antagonists are mediated via non-opioid receptors.
Topics: Animals; Blood Pressure; Cardiotonic Agents; Ligands; Myocardial Contraction; Myocardium; Naloxone; Naltrexone; Perfusion; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Ventricular Dysfunction, Left | 2006 |
Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway.
Topics: Animals; Appetite Regulation; Corn Oil; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides, Bacterial; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction | 2006 |
Involvement of mu1-opioid receptor on oxycodone-induced antinociception in diabetic mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oxycodone; Receptors, Opioid, mu; Streptozocin | 2007 |
Effect of beta-endorphin on production of antibodies and IL-4 under conditions of opioid receptor blockade.
Topics: Animals; Antibody Formation; beta-Endorphin; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Interleukin-4; Lymphocyte Activation; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Phytohemagglutinins | 2006 |
Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.
Topics: Analgesics, Opioid; Animals; Capillary Permeability; Cells, Cultured; Electrophysiology; Endothelial Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Protein Serine-Threonine Kinases; Quaternary Ammonium Compounds; Receptors, Lysosphingolipid; Receptors, Opioid, mu; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Thrombin; Transcriptional Activation | 2007 |
[Role of kappa-opioid receptors in the regulation of cardiac resistance to arrhythmogenic effects of ischemia and reperfusion].
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Myocardial Reperfusion Injury; Myocardium; Naloxone; Naltrexone; Piperazines; Pyrrolidines; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Opioid, kappa | 2006 |
Structural characterization of anhydrous naloxone- and naltrexone hydrochloride by high resolution laboratory X-ray powder diffraction and thermal analysis.
Topics: Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Desiccation; Differential Thermal Analysis; Hydrogen Bonding; Models, Molecular; Molecular Structure; Naloxone; Naltrexone; Narcotic Antagonists; Powder Diffraction; Technology, Pharmaceutical; Temperature; Water | 2007 |
Effects of loperamide on mechanical allodynia induced by herpes simplex virus type-1 in mice.
Topics: Analgesics, Opioid; Animals; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Tolerance; Female; Foot; Herpes Simplex; Herpesvirus 1, Human; Injections; Injections, Subcutaneous; Loperamide; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Physical Stimulation | 2007 |
The neural pathway of galanin in the hypothalamic arcuate nucleus of rats: activation of beta-endorphinergic neurons projecting to periaqueductal gray matter.
Topics: Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Fluorescent Antibody Technique; Galanin; Hindlimb; Hot Temperature; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Neurons; Pain; Periaqueductal Gray; Physical Stimulation; Rats; Rats, Wistar | 2007 |
A tarantula peptide against pain via ASIC1a channels and opioid mechanisms.
Topics: Acid Sensing Ion Channels; Analgesics; Animals; Area Under Curve; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalins; Membrane Proteins; Mice; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Pain; Pain Measurement; Peptides; Protein Precursors; Reaction Time; Sodium Channels; Spider Venoms; Spinal Cord; Time Factors | 2007 |
Increase in diazepam binding inhibitor expression by sustained morphine exposure is mediated via mu-opioid receptors in primary cultures of mouse cerebral cortical neurons.
Topics: Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Diazepam Binding Inhibitor; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2007 |
Two-photon excitation fluorescence cross-correlation assay for ligand-receptor binding: cell membrane nanopatches containing the human micro-opioid receptor.
Topics: Animals; Cell Line; Cell Membrane; Cross-Linking Reagents; Enkephalin, Leucine; Fluorescein; Humans; Ligands; Molecular Structure; Naloxone; Naltrexone; Nanostructures; Narcotic Antagonists; Photons; Quantum Dots; Receptors, Opioid; Solutions; Spodoptera; Titrimetry | 2007 |
Naloxone rapidly evokes endogenous kappa opioid receptor-mediated hyperalgesia in naïve mice pretreated briefly with GM1 ganglioside or in chronic morphine-dependent mice.
Topics: Analgesics, Opioid; Animals; Chronic Disease; Dipeptides; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; G(M1) Ganglioside; Hyperalgesia; Male; Mice; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 2007 |
A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells.
Topics: Animals; Benzeneacetamides; Brefeldin A; Cells, Cultured; Cycloheximide; Diprenorphine; Humans; Ligands; Naloxone; Naltrexone; Pyrrolidines; Rats; Receptors, Opioid, kappa; RNA, Messenger; Transfection; Up-Regulation | 2007 |
Intramuscular administration of morphine reduces mustard-oil-induced craniofacial-muscle pain behavior in lightly anesthetized rats.
Topics: Analgesics; Anesthesia, General; Animals; Inflammation; Injections; Injections, Intramuscular; Male; Masseter Muscle; Morphine; Mustard Plant; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Plant Oils; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Single-Blind Method; Somatostatin | 2008 |
Use of preproenkephalin knockout mice and selective inhibitors of enkephalinases to investigate the role of enkephalins in various behaviours.
Topics: Analysis of Variance; Animals; Behavior, Animal; CD13 Antigens; Disulfides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Injections, Intravenous; Mice; Mice, Inbred DBA; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Protein Precursors; Swimming | 2008 |
Morphine postconditioning protects against reperfusion injury in the isolated rat hearts.
Topics: Analgesics, Opioid; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Decanoic Acids; Dose-Response Relationship, Drug; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Morphine; Myocardial Infarction; Naloxone; Naltrexone; Narcotic Antagonists; Potassium Channels; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2008 |
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4-11), mammalian tachykinin peptides, on the modulation of pain in mice.
Topics: Analgesics; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Humans; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Tachykinins; Tropanes | 2008 |
Acute and chronic heroin dependence in mice: contribution of opioid and excitatory amino acid receptors.
Topics: Acute Disease; Animals; Behavior, Animal; Benzylidene Compounds; Chronic Disease; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heroin Dependence; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Time Factors | 2008 |
High voluntary alcohol consumption, in experimental liver cirrhosis is hardly responsive to opioid antagonist treatment.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Bilirubin; Brain; Disease Models, Animal; Drinking; Liver Cirrhosis; Male; Naloxone; Naltrexone; Narcotic Antagonists; Prothrombin Time; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, mu; Thioacetamide; Time Factors | 2008 |
Mu-opioid receptor in the nucleus submedius: involvement in opioid-induced inhibition of mirror-image allodynia in a rat model of neuropathic pain.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Enkephalin, Leucine-2-Alanine; Hyperalgesia; Ligation; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neuralgia; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Nerves; Thalamic Nuclei | 2008 |
Possible involvement of dynorphin A release via mu1-opioid receptor on supraspinal antinociception of endomorphin-2.
Topics: Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Immune Sera; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4).
Topics: Animals; Behavior, Animal; Biomarkers; Cell Line; Humans; Injections, Spinal; Male; Microglia; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4 | 2008 |
Morphine attenuates the expression of sensitization to ethanol, but opioid antagonists do not.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Brain; Central Nervous System Depressants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Protein Binding; Rats; Rats, Wistar; Tritium | 2008 |
The effects of endomorphins on striatal [3H]GABA release induced by electrical stimulation: an in vitro superfusion study in rats.
Topics: Animals; Corpus Striatum; Dipeptidyl-Peptidase IV Inhibitors; Electric Stimulation; gamma-Aminobutyric Acid; Male; Naloxone; Naltrexone; Oligopeptides; Perfusion; Rats; Rats, Wistar; Receptors, Opioid, mu; Tritium | 2009 |
Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dipyrone; Freund's Adjuvant; Indomethacin; Inflammation; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain, Postoperative; Postural Balance; Pyrazoles; Stomach Ulcer | 2008 |
[Analysis of central mechanisms involved in gastric mucosal integrity].
Topics: Animals; Arachidonic Acids; beta-Endorphin; Clonidine; Endocannabinoids; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; Excitatory Amino Acids; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nociceptin; Oligopeptides; Opioid Peptides; Oxazoles; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Opioid; Rilmenidine; Stomach Ulcer | 2008 |
Role of opioid system in modulation of pain sensitivity under conditons of low and high environmental temperature.
Topics: Analgesics, Opioid; Animals; Cold Temperature; Hot Temperature; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain Threshold; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
Evidence for the involvement of the opioid system in the antidepressant-like effect of folic acid in the mouse forced swimming test.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Drug Combinations; Excitatory Amino Acid Antagonists; Exploratory Behavior; Folic Acid; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Swimming | 2009 |
Neutral antagonist activity of naltrexone and 6beta-naltrexol in naïve and opioid-dependent C6 cells expressing a mu-opioid receptor.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Line; Cell Line, Tumor; Cyclic AMP; Drug Inverse Agonism; Drug Partial Agonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Morphine; Naloxone; Naltrexone; Peptide Fragments; Piperidines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 2009 |
Intravenous self-administration of etonitazene alone and combined with cocaine in rhesus monkeys: comparison with heroin and antagonism by naltrexone and naloxonazine.
Topics: Animals; Benzimidazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Female; Heroin; Injections, Intravenous; Macaca mulatta; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Substance Abuse, Intravenous | 2009 |
Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions.
Topics: Alternative Splicing; Analgesia; Animals; Exons; Gastrointestinal Transit; Gene Targeting; Heroin; Heterozygote; Mice; Mice, Knockout; Morphine; Mutation; Naloxone; Naltrexone; Receptors, Opioid, mu | 2009 |
Morphine-6beta-glucuronide rapidly increases pain sensitivity independently of opioid receptor activity in mice and humans.
Topics: Adolescent; Adult; Animals; Dizocilpine Maleate; Female; Humans; Hyperalgesia; Male; Mice; Mice, Knockout; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Young Adult | 2009 |
Selective mu- and kappa-opioid receptor antagonists administered into the nucleus accumbens interfere with rapid tolerance to ethanol in rats.
Topics: Animals; Drug Tolerance; Ethanol; Male; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2009 |
Role of the opioid system in incentive downshift situations.
Topics: Analgesics, Opioid; Animals; Conditioning, Classical; Dietary Sucrose; Drinking Behavior; Enkephalin, D-Penicillamine (2,5)-; Extinction, Psychological; Feeding Behavior; Female; Goals; Male; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Random Allocation; Rats; Rats, Long-Evans; Receptors, Opioid, mu; Taste Perception; Time Factors | 2009 |
Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Area Under Curve; Blotting, Western; Dopamine; Enkephalins; Gene Expression; Genes, fos; Mice; Mice, Knockout; Microdialysis; Motor Activity; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Protein Precursors; Receptors, Opioid, kappa; Reverse Transcriptase Polymerase Chain Reaction; Substance Withdrawal Syndrome | 2009 |
The antinociceptive properties of reboxetine in acute pain.
Topics: Adrenergic Antagonists; Analgesics; Animals; Antidepressive Agents; Clonidine; Disease Models, Animal; Drug Interactions; Male; Mice; Mice, Inbred ICR; Morphine; Morpholines; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Reboxetine; Receptors, Opioid, mu | 2009 |
P-glycoprotein is not involved in the differential oral potency of naloxone and naltrexone.
Topics: Acridines; Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Blotting, Western; Caco-2 Cells; Electric Impedance; Humans; Microscopy, Electron, Transmission; Molecular Structure; Naloxone; Naltrexone; Narcotic Antagonists; Tetrahydroisoquinolines | 2009 |
Opioid antagonists block the acquisition of ethanol-mediated conditioned tactile preference in infant rats.
Topics: Alcohol Drinking; Alcoholic Intoxication; Animals; Animals, Newborn; Conditioning, Classical; Ethanol; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Touch | 2009 |
Association of increased pain threshold by noise with central opioid neurons.
Topics: Analgesia; Animals; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Noise; Opioid Peptides; Pain Measurement; Pain Threshold; Receptors, Opioid, delta; Receptors, Opioid, mu; Stress, Physiological | 2009 |
A prolonged protein kinase C-mediated, opioid-related antinociceptive effect of st John's Wort in mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Compounding; Hypericum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Perylene; Phorbol Esters; Phytotherapy; Protein Kinase C; Quercetin; Somatostatin; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric; Time Factors | 2010 |
Effect of opioid compounds on feeding and activity of the cockroach, Periplaneta americana.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cockroaches; Eating; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Loss, Insensible | 2010 |
Antinociceptive effects of galanin in the central nucleus of amygdala of rats, an involvement of opioid receptors.
Topics: Amygdala; Animals; Galanin; Hindlimb; Hot Temperature; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors | 2010 |
Nucleus accumbens mu opioid receptors mediate immediate postictal decrease in locomotion after an amygdaloid kindled seizure in rats.
Topics: Amygdala; Animals; Epilepsy; Kindling, Neurologic; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Opioid, mu; Seizures | 2010 |
Emerging new therapeutic options for the management of opioid induced constipation.
Topics: Alprostadil; Analgesics, Opioid; Constipation; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Laxatives; Lubiprostone; Naloxone; Naltrexone; Narcotic Antagonists; Oxycodone; Quaternary Ammonium Compounds | 2010 |
Evidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts.
Topics: 8,11,14-Eicosatrienoic Acid; Analgesics, Opioid; Animals; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin | 2010 |
Alteration of intravenous nicotine self-administration by opioid receptor agonist and antagonists in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nicotine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration; Tobacco Use Disorder | 2010 |
The diverse clinical uses of opioid receptor drugs.
Topics: Analgesics, Opioid; Buprenorphine; Drug Combinations; Humans; Methadone; Naloxone; Naltrexone; Narcotic Antagonists | 2010 |
The μ-opioid receptor variant N190K is unresponsive to peptide agonists yet can be rescued by small-molecule drugs.
Topics: Amino Acid Substitution; Black or African American; Cell Line; Cholesterol, HDL; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Genes, Reporter; Genotype; Humans; Luciferases; Mutagenesis, Site-Directed; Mutation, Missense; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Peptides; Polymorphism, Single Nucleotide; Protein Isoforms; Protein Transport; Radioligand Assay; Receptors, Opioid, mu; Signal Transduction; White People | 2010 |
Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model.
Topics: Analgesics; Animals; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Peptides, Cyclic; Receptors, Opioid, mu | 2010 |
Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation.
Topics: Animals; Cacao; Catechin; Decanoic Acids; Dose-Response Relationship, Drug; Hydroxy Acids; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Potassium Channel Blockers; Receptors, Cell Surface; Receptors, Opioid, delta | 2010 |
Acupuncture inhibits GABA neuron activity in the ventral tegmental area and reduces ethanol self-administration.
Topics: Action Potentials; Acupuncture Therapy; Animals; Drug Interactions; Electric Stimulation; Ethanol; gamma-Aminobutyric Acid; Male; Naloxone; Naltrexone; Neurons; Rats; Rats, Wistar; Self Administration; Sucrose; Tail; Ventral Tegmental Area | 2010 |
Effect of ultra-rapid opiate detoxification on withdrawal syndrome.
Topics: Adult; Anesthesia, General; Female; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome | 2010 |
Dorsal hippocampal opioidergic system modulates anxiety-like behaviors in adult male Wistar rats.
Topics: Analgesics, Opioid; Animals; Anxiety; CA1 Region, Hippocampal; Disease Models, Animal; Enkephalin, D-Penicillamine (2,5)-; Male; Maze Learning; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 2010 |
The antidepressant-like effect of human opiorphin via opioid-dependent pathways in mice.
Topics: Animals; Antidepressive Agents; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Humans; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Salivary Proteins and Peptides; Signal Transduction | 2011 |
Endogenously released opioids mediate meal-induced gastric relaxation via peripheral mu-opioid receptors.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Eating; Female; Food; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Satiation; Stomach | 2011 |
μ-Opioid receptors in the nucleus accumbens shell region mediate the effects of amphetamine on inhibitory control but not impulsive choice.
Topics: Amphetamine; Analgesics, Opioid; Animals; Attention; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Impulsive Behavior; Inhibition, Psychological; Male; Motivation; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Peptides; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, mu; Reinforcement Schedule | 2011 |
Morphine postconditioning attenuates ICAM-1 expression on endothelial cells.
Topics: Animals; Benzophenanthridines; Endothelial Cells; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Protein Isoforms; Protein Kinase C; Receptors, Opioid; Reperfusion Injury; Signal Transduction; Umbilical Veins | 2011 |
Delayed postoperative latent pain sensitization revealed by the systemic administration of opioid antagonists in mice.
Topics: Animals; Dizocilpine Maleate; Dynorphins; Hyperalgesia; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Piperidines; Postoperative Complications; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Remifentanil; Spinal Cord | 2011 |
Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2.
Topics: Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Electrophysiology; Female; Ganglia, Spinal; Male; Mice; Mice, Mutant Strains; Naloxone; Naltrexone; Pain Measurement; Peptide Fragments; Receptors, Opioid, mu; Somatostatin | 2011 |
Multiple opioid receptors mediate the hypotensive response induced by central 5-HT(3) receptor stimulation.
Topics: Animals; Biguanides; Blood Pressure; Heart Rate; Hypotension; Male; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists | 2011 |
The action of a synthetic derivative of Met5-enkephalin-Arg6-Phe7 on behavioral and endocrine responses.
Topics: Animals; Behavior, Animal; Enkephalin, Methionine; Enkephalins; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System | 2011 |
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens.
Topics: Acetaldehyde; Animals; Enzyme Activation; Ethanol; Extracellular Signal-Regulated MAP Kinases; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Wistar; Receptors, Opioid, mu; Reinforcement, Psychology; Saccharin; Self Administration | 2011 |
Central administration of neuronostatin induces antinociception in mice.
Topics: Acute Pain; Analgesics; Animals; Dose-Response Relationship, Drug; Immunohistochemistry; Infusions, Intraventricular; Male; Melanocyte-Stimulating Hormones; Mice; Models, Animal; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Peptide Hormones; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Receptor, Melanocortin, Type 3; Receptor, Melanocortin, Type 4 | 2011 |
Opioid-like antinociceptive effects of oral administration of a lectin purified from the seeds of Canavalia brasiliensis.
Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Canavalia; Mice; Morphinans; Naloxone; Naltrexone; Nociception; Pain Measurement; Plant Lectins; Receptors, Opioid, delta; Receptors, Opioid, kappa; Seeds | 2013 |
YFa and analogs: investigation of opioid receptors in smooth muscle contraction.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Cholinergic Agonists; Dynorphins; Enkephalin, Methionine; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Oligopeptides; Receptors, Opioid; Vas Deferens | 2011 |
The relationship between naloxone-induced cortisol and delta opioid receptor availability in mesolimbic structures is disrupted in alcohol-dependent subjects.
Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Area Under Curve; Case-Control Studies; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Ligands; Limbic System; Linear Models; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Pituitary-Adrenal System; Positron-Emission Tomography; Receptors, Opioid, delta; Stress, Psychological; Young Adult | 2013 |
Synthesis and biological evaluation of naloxone and naltrexone-derived hybrid opioids.
Topics: Amino Acid Sequence; Analgesics, Opioid; Binding Sites; Inhibitory Concentration 50; Microscopy, Electron, Scanning; Molecular Sequence Data; Molecular Structure; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Protein Binding; Receptors, Opioid; Solid-Phase Synthesis Techniques | 2012 |
Cathepsin E induces itch-related response through the production of endothelin-1 in mice.
Topics: Animals; Behavior, Animal; Cathepsin E; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Histamine Release; Keratinocytes; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pepstatins; Peptides, Cyclic; Protease Inhibitors; Pruritus; Receptor, PAR-2; RNA, Messenger; Skin | 2012 |
κ-Opioid receptors within the nucleus accumbens shell mediate pair bond maintenance.
Topics: Aggression; Animals; Arvicolinae; Autoradiography; Brain; Corticosterone; Dose-Response Relationship, Drug; Female; Male; Microinjections; Naloxone; Naltrexone; Nucleus Accumbens; Pair Bond; Peptide Fragments; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sex Characteristics; Somatostatin; Testosterone | 2012 |
Centrally administered apelin-13 induces depression-like behavior in mice.
Topics: Amino Acid Sequence; Animals; Apelin Receptors; Corticotropin-Releasing Hormone; Depression; Injections; Injections, Intraventricular; Intercellular Signaling Peptides and Proteins; Male; Mice; Motor Activity; Naloxone; Naltrexone; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptors, Corticotropin-Releasing Hormone; Receptors, G-Protein-Coupled; Receptors, Opioid, kappa; Rotarod Performance Test; Single-Blind Method | 2012 |
Supraspinal antinociceptive effect of apelin-13 in a mouse visceral pain model.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Drug Synergism; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Intercellular Signaling Peptides and Proteins; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Visceral Pain | 2012 |
Non-analgesic effects of opioids: management of opioid-induced constipation by peripheral opioid receptor antagonists: prevention or withdrawal?
Topics: Age Factors; Analgesics, Opioid; Constipation; Defecation; Drug Combinations; Gastrointestinal Tract; Humans; Laxatives; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Predictive Value of Tests; Prevalence; Quaternary Ammonium Compounds; Receptors, Opioid; Risk Factors | 2012 |
A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence.
Topics: Animals; Buprenorphine; Cocaine; Cocaine-Related Disorders; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2012 |
Analgesic properties of chimeric peptide based on morphiceptin and PFRTic-amide.
Topics: Analgesia; Analgesics, Opioid; Animals; Arginine; Dose-Response Relationship, Drug; Endorphins; Guinea Pigs; Male; Mice; Morphinans; Naloxone; Naltrexone; Neuropeptides; Opioid Peptides; Proline; Receptors, Neuropeptide; Tetrahydroisoquinolines; Time Factors | 2012 |
Opioid dependence.
Topics: Buprenorphine; Clonidine; Evidence-Based Medicine; Humans; Inactivation, Metabolic; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Prognosis; Risk Factors; Substance Withdrawal Syndrome; Time Factors | 2012 |
Spinal cord stimulation reduces hypersensitivity through activation of opioid receptors in a frequency-dependent manner.
Topics: Analgesics, Opioid; Animals; Hyperalgesia; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neuralgia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord; Spinal Cord Stimulation | 2013 |
Antinociceptive action of isolated mitragynine from Mitragyna Speciosa through activation of opioid receptor system.
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Male; Mice; Mice, Inbred ICR; Mitragyna; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Opioid; Secologanin Tryptamine Alkaloids | 2012 |
Involvement of peripheral cannabinoid and opioid receptors in β-caryophyllene-induced antinociception.
Topics: Animals; Cannabinoids; Endorphins; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Pain; Pain Measurement; Polycyclic Sesquiterpenes; Receptor, Cannabinoid, CB2; Sesquiterpenes | 2013 |
The cardiovascular effects of a chimeric opioid peptide based on morphiceptin and PFRTic-NH2.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Bradycardia; Endorphins; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar | 2013 |
Kappa-opioid receptors mediate the antidepressant-like activity of hesperidin in the mouse forced swimming test.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Hesperidin; Male; Mice; Naloxone; Naltrexone; Receptors, Opioid, kappa; Receptors, Purinergic P1; Swimming | 2013 |
Opiate receptor antagonists for treatment of severe pruritus associated with advanced cholestatic liver disease.
Topics: Aged, 80 and over; Cholestasis; Comorbidity; Humans; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pruritus; Quality of Life; Quaternary Ammonium Compounds | 2013 |
[Effect of opioid receptor blockade on antibody response and proliferative response under stress conditions].
Topics: Animals; Antibody Formation; B-Lymphocytes; Cell Proliferation; Immobilization; Immunity, Humoral; Lymphocyte Count; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Rotation; Spleen; Stress, Physiological | 2013 |
Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive Gαo protein.
Topics: Analgesics, Opioid; Animals; Brain; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Humans; Hyperalgesia; Inhibitory Postsynaptic Potentials; Isotopes; Male; Methadone; Mice; Mice, Transgenic; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Pain Measurement; Patch-Clamp Techniques; Pertussis Toxin; Protein Binding; Reaction Time; RGS Proteins; Signal Transduction; Spinal Cord | 2013 |
Rewarding effects of ethanol combined with low doses of morphine through dopamine D1 receptors.
Topics: Analgesics, Opioid; Animals; Benzazepines; Central Nervous System Depressants; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward | 2013 |
Co-activation of μ- and δ-opioid receptors elicits tolerance to morphine-induced ventilatory depression via generation of peroxynitrite.
Topics: Analysis of Variance; Animals; Antidotes; Drug Tolerance; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Penicillamine; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiratory Insufficiency; Time Factors | 2013 |
Involvement of μ-opioid receptors in antinociceptive action of botulinum toxin type A.
Topics: Analgesics; Animals; Botulinum Toxins, Type A; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Naltrexone; Narcotic Antagonists; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Receptors, Opioid, mu | 2013 |
Effect of naloxone on ischemic acute kidney injury in the mouse.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Hypothalamus, Anterior; Injections, Intraperitoneal; Injections, Intraventricular; Kidney; Male; Mice; Mice, Inbred ICR; Molecular Targeted Therapy; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; Receptors, Opioid, mu; Renal Insufficiency; Reperfusion Injury | 2013 |
Long-term antinociception by electroacupuncture is mediated via peripheral opioid receptors in free-moving rats with inflammatory hyperalgesia.
Topics: Acupuncture Analgesia; Acupuncture Points; Animals; Disease Models, Animal; Electroacupuncture; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Naloxone; Naltrexone; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid; Time | 2013 |
Synthesis, modeling, and pharmacological evaluation of UMB 425, a mixed μ agonist/δ antagonist opioid analgesic with reduced tolerance liabilities.
Topics: Analgesics, Opioid; Animals; CHO Cells; Computer Simulation; Cricetulus; Drug Evaluation, Preclinical; Drug Tolerance; Humans; Male; Mice; Models, Chemical; Molecular Structure; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptive Pain; Pain Measurement; Protein Binding; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Thebaine; Transfection | 2013 |
A novel, potent, oral active and safe antinociceptive pyrazole targeting kappa opioid receptors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Benzofurans; Diterpenes; Drug Administration Routes; Drug Evaluation, Preclinical; Idazoxan; Male; Mice; Molecular Structure; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrazoles; Pyrrolidines; Radioligand Assay; Receptors, Opioid, kappa; Tritium; TRPV Cation Channels | 2013 |
Physical presence of nor-binaltorphimine in mouse brain over 21 days after a single administration corresponds to its long-lasting antagonistic effect on κ-opioid receptors.
Topics: Analgesics; Animals; Benzeneacetamides; Brain; Chromatography, High Pressure Liquid; Hot Temperature; Injections, Intraventricular; Membranes; Mice; Mice, Inbred C57BL; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrrolidines; Receptors, Opioid, kappa; Reference Standards; Tandem Mass Spectrometry; Time Factors | 2013 |
Pharmacokinetic evidence for the long-lasting effect of nor-binaltorphimine, a potent kappa opioid receptor antagonist, in mice.
Topics: Animals; Brain; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Time Factors | 2013 |
Different types of opioid receptors involved in the suppression of LH secretion in lactating sheep.
Topics: Animals; Female; Gene Expression Regulation; Guanidines; Lactation; Luteinizing Hormone; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Sheep | 2013 |
Mechanisms underlying the antinociceptive effect of mangiferin in the formalin test.
Topics: Analgesics; Animals; Capsaicin; Formaldehyde; Glyburide; Male; Naloxone; Naltrexone; NG-Nitroarginine Methyl Ester; Nociception; Quinoxalines; Rats; Rats, Wistar; Serotonin; Xanthones | 2013 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the anterior pretectal nucleus.
Topics: Analgesia; Animals; Atropine; Bicuculline; Electroacupuncture; GABA-A Receptor Antagonists; Male; Mesencephalon; Methiothepin; Methysergide; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Pain Management; Rats; Rats, Wistar; Serotonin Antagonists; Somatostatin | 2013 |
Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.
Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enkephalins; Fentanyl; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 2013 |
Involvement of spinal release of α-neo-endorphin on the antinociceptive effect of TAPA.
Topics: Analgesia; Analgesics, Opioid; Animals; Endorphins; Gene Expression; Immune Sera; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Tail | 2013 |
Antinociceptive activity of a synthetic oxopyrrolidine-based compound, ASH21374, and determination of its possible mechanisms.
Topics: Analgesics; Analgesics, Opioid; Animals; Aspirin; Capsaicin; Cyclic GMP; Glutamic Acid; Male; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Naloxone; Naltrexone; Nitric Oxide; Pyrrolidines; Rats, Sprague-Dawley; Receptors, Opioid | 2013 |
[Analgesic properties of morpholinoethylimidazobenzimidazole derivative RU-1205].
Topics: Analgesics; Animals; Animals, Outbred Strains; Benzimidazoles; Butorphanol; Male; Mice; Morpholines; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Pain; Pain Measurement; Rats; Receptors, Opioid, kappa | 2013 |
Central antinociception induced by ketamine is mediated by endogenous opioids and μ- and δ-opioid receptors.
Topics: Aminopeptidases; Analgesics; Animals; Brain; Cinnamates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hot Temperature; Ketamine; Leucine; Male; Mice; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptive Pain; Opioid Peptides; Pain Perception; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2014 |
Desensitization of functional µ-opioid receptors increases agonist off-rate.
Topics: Analgesics, Opioid; Animals; Brain; Enkephalins; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Kinetics; Ligands; Naloxone; Naltrexone; Photolysis; Potassium; Rats; Receptors, Opioid, mu | 2014 |
Opioid receptors in the prelimbic cortex modulate restraint stress-induced cardiovascular responses in the rat.
Topics: Animals; Arterial Pressure; Body Temperature; Cerebral Cortex; Dose-Response Relationship, Drug; Heart Rate; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptors, Opioid; Restraint, Physical; Stress, Psychological; Tachycardia | 2014 |
Opioid modulation of prolactin secretion induced by stress during late pregnancy. Role of ovarian steroids.
Topics: Analgesics, Opioid; Animals; Estradiol; Female; Mifepristone; Naloxone; Naltrexone; Narcotic Antagonists; Ovary; Pregnancy; Progesterone; Prolactin; Rats; Rats, Wistar; Steroids; Tamoxifen | 2014 |
The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours.
Topics: Analgesics, Opioid; Animals; CHO Cells; Compulsive Behavior; Cricetinae; Cricetulus; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Indans; Ligands; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Protein Binding; Receptors, Opioid, mu; Reward; Treatment Outcome; Triazoles | 2015 |
Involvement of μ- and δ-opioid receptor function in the rewarding effect of (±)-pentazocine.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Isomerism; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Pentazocine; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Reward | 2015 |
The effectiveness of opioid substitution treatments for patients with opioid dependence: a systematic review and multiple treatment comparison protocol.
Topics: Buprenorphine; Buprenorphine, Naloxone Drug Combination; Heroin; Humans; Methadone; Naloxone; Naltrexone; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Research Design; Systematic Reviews as Topic | 2014 |
Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and κ-opioid receptors in rat spinal cord nociceptive reflexes.
Topics: Adenosine; Animals; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fentanyl; Inflammation; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord | 2014 |
The opioid system majorly contributes to preference for fat emulsions but not sucrose solutions in mice.
Topics: Administration, Oral; Animals; Behavior, Animal; Choice Behavior; Dietary Fats; Eating; Emulsions; Food Preferences; Male; Mice; Mice, Inbred BALB C; Naloxone; Naltrexone; Narcotic Antagonists; Phospholipids; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Soybean Oil; Sucrose | 2015 |
Prenatal exposure to vanilla or alcohol induces crawling after these odors in the neonate rat: The role of mu and kappa opioid receptor systems.
Topics: Analysis of Variance; Animals; Animals, Newborn; Drug-Seeking Behavior; Ethanol; Female; Locomotion; Maternal Exposure; Naloxone; Naltrexone; Odorants; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Vanilla | 2015 |
Effects of β-endorphin on functional activity of mouse splenocytes under conditions of in vivo blockade of μ,δ-opioid receptors.
Topics: Animals; beta-Endorphin; Concanavalin A; Interferon-gamma; Interleukin-2; Interleukin-4; Male; Mice; Naloxone; Naltrexone; Receptors, Opioid, delta; Spleen | 2015 |
Types of skin afferent fibers and spinal opioid receptors that contribute to touch-induced inhibition of heart rate changes evoked by noxious cutaneous heat stimulation.
Topics: Analgesics, Opioid; Animals; Heart Rate; Hot Temperature; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Management; Rats, Wistar; Receptors, Opioid; Reflex; Skin; Spinal Cord; Touch | 2015 |
Development and validation of a bioanalytical method for the simultaneous determination of heroin, its main metabolites, naloxone and naltrexone by LC-MS/MS in human plasma samples: Application to a clinical trial of oral administration of a heroin/naloxo
Topics: Administration, Oral; Calibration; Chromatography, Liquid; Codeine; Formates; Healthy Volunteers; Heroin; Humans; Hydrogen-Ion Concentration; Limit of Detection; Morphine; Naloxone; Naltrexone; Quality Control; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry | 2015 |
Morphine Modulates Interleukin-4- or Breast Cancer Cell-induced Pro-metastatic Activation of Macrophages.
Topics: Animals; Arginase; Bone Marrow Cells; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Coculture Techniques; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-4; Macrophage Activation; Macrophages; Mammary Glands, Animal; Matrix Metalloproteinase 9; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Quaternary Ammonium Compounds; Receptors, Cell Surface; Receptors, Immunologic; Signal Transduction | 2015 |
Pharmacotherapy: Quest for the quitting pill.
Topics: Animals; Behavior, Addictive; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clinical Trials as Topic; Cocaine-Related Disorders; Counseling; Dopamine; Drug Discovery; Drug Industry; Humans; Ibogaine; Lobeline; Molecular Targeted Therapy; Naloxone; Naltrexone; Oligopeptides; Opioid-Related Disorders; Pleasure; Rats; Receptors, Nicotinic; Reward; Substance-Related Disorders; Tobacco Use Disorder; Vaccines; Vesicular Monoamine Transport Proteins | 2015 |
Species-specific lipophilicity of morphine antagonists.
Topics: 1-Octanol; Hydrogen-Ion Concentration; Naloxone; Naltrexone; Narcotic Antagonists; Oxymorphone; Potentiometry; Water | 2015 |
Role of µ, κ, and δ opioid receptors in tibial inhibition of bladder overactivity in cats.
Topics: Acetic Acid; Animals; Cats; Female; Male; Morphinans; Naloxone; Naltrexone; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tibial Nerve; Transcutaneous Electric Nerve Stimulation; Urinary Bladder, Overactive | 2015 |
Brain opioid and nociceptin receptors are involved in regulation of bombesin-induced activation of central sympatho-adrenomedullary outflow in the rat.
Topics: Adrenal Medulla; Animals; Bombesin; Brain; Catecholamines; Morphinans; Naloxone; Naltrexone; Nociceptin Receptor; Rats; Receptors, Opioid; Sympathetic Nervous System | 2016 |
Opioid-Induced Constipation Part 2: Newer Therapies #295.
Topics: Analgesics, Opioid; Constipation; Humans; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Polyethylene Glycols; Quaternary Ammonium Compounds | 2015 |
Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4.
Topics: Animals; Cell Line; Cells, Cultured; Interferon-beta; Interleukin-1beta; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Microglia; Naloxone; Naltrexone; Narcotic Antagonists; Nitric Oxide; Phagocytosis; Rats, Sprague-Dawley; Reactive Oxygen Species; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Opioid antagonists block acetaldehyde-induced increments in dopamine neurons activity.
Topics: Acetaldehyde; Alcoholism; Animals; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Ventral Tegmental Area | 2016 |
Differences in the morphine-induced inhibition of small and large intestinal transit: Involvement of central and peripheral μ-opioid receptors in mice.
Topics: Analgesics, Opioid; Animals; Central Nervous System; Dose-Response Relationship, Drug; Gastrointestinal Transit; Injections, Intraventricular; Intestine, Large; Intestine, Small; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Peripheral Nervous System; Receptors, Opioid, mu | 2016 |
Coactivation of μ- and κ-Opioid Receptors May Mediate the Protective Effect of Testosterone on the Development of Temporomandibular Joint Nociception in Male Rats.
Topics: Animals; Brain Stem; Facial Pain; Formaldehyde; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Nociceptive Pain; Orchiectomy; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Temporomandibular Joint; Temporomandibular Joint Disorders; Testosterone; Trigeminal Caudal Nucleus | 2016 |
Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids.
Topics: Analgesics, Opioid; Anesthetics; Animals; Brain; Cocaine; Conditioning, Operant; Discrimination, Psychological; Dopamine; Extinction, Psychological; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Remifentanil; Self Administration; Time Factors | 2016 |
Opioid system mediated anti-nociceptive effect of agomelatine in mice.
Topics: Acetamides; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Naltrexone; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rotarod Performance Test | 2016 |
Methyl-orvinol-Dual activity opioid receptor ligand inhibits gastrointestinal transit and alleviates abdominal pain in the mouse models mimicking diarrhea-predominant irritable bowel syndrome.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdominal Pain; Analgesics; Analgesics, Opioid; Animals; Colon; Diarrhea; Disease Models, Animal; Gastrointestinal Motility; Gastrointestinal Transit; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Receptors, Opioid; Thebaine | 2017 |
The differential effects of low and high doses of apelin through opioid receptors on the blood pressure of rats with renovascular hypertension.
Topics: Animals; Antihypertensive Agents; Apelin; Benzophenanthridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Hypertension, Renovascular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Protein Kinase C; Rats; Rats, Wistar; Receptors, Opioid | 2017 |
Nalmefene Prevents Alcohol-Induced Neuroinflammation and Alcohol Drinking Preference in Adolescent Female Mice: Role of TLR4.
Topics: Alcohol Drinking; Alcohol-Related Disorders; Animals; Astrocytes; Cell Death; Chemokines; Drug Evaluation, Preclinical; Ethanol; Female; Membrane Microdomains; Mice, Inbred C57BL; Mice, Knockout; Myelin Sheath; Naloxone; Naltrexone; Narcotic Antagonists; Primary Cell Culture; Toll-Like Receptor 4 | 2017 |
Effects of ICI204,448, naloxone methiodide and levocetirizine on the scratching behavior induced by a κ-opioid antagonist, nor-BNI, in ICR mice.
Topics: Animals; Behavior, Animal; Cetirizine; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pyrrolidines; Quaternary Ammonium Compounds | 2017 |
Opioid system contribution to the antidepressant-like action of m-trifluoromethyl-diphenyl diselenide in mice: A compound devoid of tolerance and withdrawal syndrome.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Organosilicon Compounds; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Swimming | 2017 |
Opioid receptors mediate inotropic and depressor effects of apelin in rats with 2K1C-induced chronic renovascular hypertension.
Topics: Animals; Apelin; Blood Pressure; Gene Expression Regulation; Hypertension; Intercellular Signaling Peptides and Proteins; Kidney Diseases; Male; Myocardial Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid | 2018 |
On-chip pulsed electromembrane extraction as a new concept for analysis of biological fluids in a small device.
Topics: Blood Chemical Analysis; Codeine; Electrochemistry; Electrodes; Humans; Limit of Detection; Liquid-Liquid Extraction; Membranes, Artificial; Naloxone; Naltrexone; Solvents; Urinalysis | 2017 |
Assessing and improving organizational readiness to implement substance use disorder treatment in primary care: findings from the SUMMIT study.
Topics: Adult; Alcohol-Related Disorders; Attitude of Health Personnel; Buprenorphine; Cognitive Behavioral Therapy; Delayed-Action Preparations; Delivery of Health Care; Feasibility Studies; Female; Financing, Government; Humans; Los Angeles; Male; Middle Aged; Motivational Interviewing; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Primary Health Care; United States | 2017 |
The effects of recurrent hypoglycaemia and opioid antagonists on the adrenal catecholamine synthetic capacity in a rat model of HAAF.
Topics: Animals; Blood Glucose; Disease Models, Animal; Epinephrine; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Naloxone; Naltrexone; Narcotic Antagonists; Pure Autonomic Failure; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Serine; Tyrosine 3-Monooxygenase | 2018 |
The Chemokine CCL4 (MIP-1β) Evokes Antinociceptive Effects in Mice: a Role for CD4
Topics: Analgesics; Animals; CD4-Positive T-Lymphocytes; Chemokine CCL4; Enkephalin, Methionine; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Pain; Pain Measurement | 2019 |
Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Mitragyna; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids; Self Administration | 2019 |
In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment of Major Depressive Disorder.
Topics: Animals; beta-Arrestins; Buprenorphine; Cell Line; CHO Cells; Cricetulus; Depressive Disorder, Major; Drug Combinations; GTP-Binding Proteins; HEK293 Cells; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, mu | 2018 |
Tackling addiction in primary care.
Topics: Alcoholism; Buprenorphine; Drug Combinations; Humans; Illicit Drugs; Interdisciplinary Communication; Intersectoral Collaboration; Mass Screening; Minnesota; Naloxone; Naltrexone; Opioid-Related Disorders; Prescription Drugs; Primary Health Care; Referral and Consultation; Substance-Related Disorders | 2017 |
The antihyperalgesic effect of docosahexaenoic acid in streptozotocin-induced neuropathic pain in the rat involves the opioidergic system.
Topics: Analgesics; Analgesics, Opioid; Animals; Diabetic Neuropathies; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Gabapentin; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma; Streptozocin | 2019 |
Possible involvement of the μ opioid receptor in the antinociception induced by sinomenine on formalin-induced nociceptive behavior in mice.
Topics: Administration, Oral; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morphinans; Naloxone; Naltrexone; Nociception; Receptors, Opioid, mu; Spinal Cord | 2019 |
A further assessment of a role for Toll-like receptor 4 in the reinforcing and reinstating effects of opioids.
Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Heroin; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Toll-Like Receptor 4 | 2020 |
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol | 2019 |
The Blockade of µ1- and κ-Opioid Receptors in the Inferior Colliculus Decreases the Expression of Panic Attack-Like Behaviours Induced by Chemical Stimulation of the Dorsal Midbrain.
Topics: Animals; Behavior, Animal; Bicuculline; Exploratory Behavior; GABA-A Receptor Antagonists; Inferior Colliculi; Male; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Panic; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2019 |
Changes in murine respiratory dynamics induced by aerosolized carfentanil inhalation: Efficacy of naloxone and naltrexone.
Topics: Administration, Inhalation; Aerosols; Analgesics, Opioid; Animals; Computer Simulation; Dose-Response Relationship, Drug; Fentanyl; Humans; Lung; Male; Mice; Models, Biological; Naloxone; Naltrexone; Narcotic Antagonists; Plethysmography, Whole Body; Respiration; Respiratory Insufficiency; Risk Assessment | 2019 |
Hide and Seek: Overcoming the Masking Effect of Opioid Antagonists in Activity-Based Screening Tests.
Topics: Analgesics, Opioid; Animals; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Abuse Detection | 2019 |
Peripheral antinociception induced by ketamine is mediated by the endogenous opioid system.
Topics: Analgesics; Animals; Cinnamates; Dinoprostone; Ketamine; Male; Mice; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu | 2019 |
Pharmacological evaluation underlying the antinociceptive activity of two new hybrids NSAIDs tetrahydropyran derivatives.
Topics: Adenosine Triphosphate; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Formaldehyde; Glyburide; Humans; Male; Mice; Naloxone; Naltrexone; NG-Nitroarginine Methyl Ester; Pain; Pain Measurement; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2020 |
Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Carrageenan; Dipyrone; Hydrolysis; Hyperalgesia; Indoles; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Opioid, kappa; Somatostatin | 2020 |
The Role of Cardiac Opioid Receptors in the Cardioprotective Effect of Continuous Normobaric Hypoxia.
Topics: Adaptation, Physiological; Animals; Benzylidene Compounds; Creatine Kinase; Hypoxia; Male; Myocardial Reperfusion Injury; Myocardium; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Organ Culture Techniques; Peptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrahydroisoquinolines | 2020 |
Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors.
Topics: Animals; beta-Arrestins; CHO Cells; Cricetulus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fluorescence Resonance Energy Transfer; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Phosphorylation; Protein Multimerization; Receptors, Opioid, mu; Single Molecule Imaging | 2020 |
Naloxone-Induced Acute Opioid Withdrawal in a Stabilized Extended-Release Naltrexone-Treated Patient.
Topics: Analgesics, Opioid; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Substance Withdrawal Syndrome | 2020 |
A low pKa ligand inhibits cancer-associated pain in mice by activating peripheral mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cancer Pain; Cell Line, Tumor; Fentanyl; Hydrogen-Ion Concentration; Hyperalgesia; Ligands; Male; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Receptors, Opioid, mu | 2020 |
Mechanisms of QT prolongation by buprenorphine cannot be explained by direct hERG channel block.
Topics: Buprenorphine; Electrocardiography; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Ion Channel Gating; Methadone; Myocytes, Cardiac; Naloxone; Naltrexone; Potassium Channel Blockers; Receptors, Opioid; Time Factors | 2020 |
A study of the effectiveness of naltrexone in preventing recurrence of methadone poisoning in opioid-naive children.
Topics: Adolescent; Aftercare; Analgesics, Opioid; Child; Child, Preschool; Female; Hospitalization; Humans; Infant; Intensive Care Units; Iran; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neoplasms; Patient Discharge; Poisoning; Recurrence; Retrospective Studies | 2021 |
Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone.
Topics: Analgesics, Opioid; Heroin; Morphine; Naloxone; Naltrexone | 2021 |
Comparing actual and forecasted numbers of unique patients dispensed select medications for opioid use disorder, opioid overdose reversal, and mental health, during the COVID-19 pandemic, United States, January 2019 to May 2020.
Topics: Analgesics, Opioid; Angiotensin Receptor Antagonists; Antidepressive Agents; Benzodiazepines; Buprenorphine; COVID-19; Drug Utilization; Forecasting; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Naloxone; Naltrexone; Opiate Overdose; Opioid-Related Disorders; Pandemics; SARS-CoV-2; United States | 2021 |
Naloxone-induced analgesia mediated by central kappa opioid system in chronic inflammatory pain.
Topics: Analgesia; Analgesics, Opioid; Animals; Chronic Pain; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa | 2021 |
Endogenous opioid and cannabinoid systems modulate the muscle pain: A pharmacological study into the peripheral site.
Topics: Animals; Arachidonic Acids; Carrageenan; Cinnamates; Endocannabinoids; Hyperalgesia; Male; Monoacylglycerol Lipases; Morphine Derivatives; Myalgia; Naloxone; Naltrexone; Pain Measurement; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2021 |
Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Docking.
Topics: Acute Pain; Analgesics; Animals; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Cycloheptanes; Humans; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Mice; Models, Molecular; Molecular Docking Simulation; Morphine; Movement; Naloxone; Naltrexone; Nociceptin; Oligopeptides; Opioid Peptides; Pain Management; Piperidines; Receptors, Opioid, mu | 2021 |
Increasingly powerful opioid antagonists are not necessary.
Topics: Humans; Naloxone; Naltrexone; Narcotic Antagonists | 2022 |
Trends in pharmacy-based dispensing of buprenorphine, extended-release naltrexone, and naloxone during the COVID-19 pandemic by age and sex - United States, March 2019 - December 2020.
Topics: Adult; Analgesics, Opioid; Buprenorphine; COVID-19; Female; Humans; Male; Middle Aged; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Pandemics; Pharmacy; SARS-CoV-2; United States; Young Adult | 2022 |
Opioid Antagonist Nanodrugs Successfully Attenuate the Severity of Ischemic Stroke.
Topics: Analgesics, Opioid; Animals; Ischemic Stroke; Mice; Morphine; Naloxone; Naltrexone; Nanoparticles; Narcotic Antagonists; Opioid-Related Disorders; Oxycodone; Stroke; Tight Junction Proteins | 2022 |
Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone.
Topics: Analgesics, Opioid; Imidazoles; Naloxone; Naltrexone; Receptors, Opioid; Sulfonamides; Thiophenes | 2022 |
Opioid antagonism in humans: a primer on optimal dose and timing for central mu-opioid receptor blockade.
Topics: Analgesics, Opioid; Animals; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu | 2023 |
Naloxone Versus Methylnaltrexone for Opioid-Induced Constipation in Critically Ill Patients.
Topics: Adult; Analgesics, Opioid; Constipation; Critical Illness; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Opioid-Induced Constipation; Pain; Prospective Studies; Quaternary Ammonium Compounds; Retrospective Studies | 2023 |
Promising biomedical subcutaneous delivery system in opioid disaccustom process: In vitro/in vivo evaluation of naloxone microparticles on antagonist effect of morphine.
Topics: Analgesics, Opioid; Animals; Guinea Pigs; Humans; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma | 2023 |
In brief: Over-the-counter Narcan nasal spray.
Topics: Analgesics, Opioid; Buprenorphine; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Nasal Sprays; Opiate Substitution Treatment; Opioid-Related Disorders | 2023 |
Racial Inequality in Receipt of Medications for Opioid Use Disorder.
Topics: Aged; Analgesics, Opioid; Benzodiazepines; Black or African American; Buprenorphine; Healthcare Disparities; Hispanic or Latino; Humans; Medicare; Naloxone; Naltrexone; Narcotic Antagonists; Opiate Overdose; Opioid-Related Disorders; United States; White | 2023 |
Nalmefene nasal spray (Opvee) for reversal of opioid overdose.
Topics: Analgesics, Opioid; Drug Overdose; Humans; Naloxone; Naltrexone; Narcotic Antagonists; Nasal Sprays; Opiate Overdose | 2023 |