naltrexone has been researched along with morphine-6-glucuronide in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 11 (61.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Brune, K; Geisslinger, G; Schmidt, N | 1 |
| Karasawa, F; Kitani, Y; Kuribara, H; Morita, T; Sato, T; Uchihashi, Y | 1 |
| Brown, GP; Chang, A; King, MA; Leventhal, L; Pasternak, GW; Rossi, GC; Yang, K | 1 |
| Aasmundstad, TA; Alkana, RL; Grung, M; Handal, M; Mørland, J; Skurtveit, S | 1 |
| Easterling, KW; Holtzman, SG | 1 |
| Izzo, E; King, M; Koob, GF; Pasternak, GW; Walker, JR | 1 |
| Chieng, B; Christie, MJ; Osborne, PB | 1 |
| Carrigan, KA; Lysle, DT | 1 |
| Izenwasser, S; Platt, DM; Rowlett, JK; Spealman, RD | 1 |
| Antonilli, L; Badiani, A; Caprioli, D; Nencini, P; Petecchia, E | 1 |
| Antonilli, L; Badiani, A; Brusadin, V; Graziani, M; Nencini, P; Togna, AR; Togna, G; Viola, S | 1 |
| Dahan, A; Mousavi Gourabi, B; Teppema, LJ; van Dorp, E; van Kleef, JW | 1 |
| Arout, CA; Dahan, A; Kest, B; Kowalczyk, WJ; Morariu, AM; Sarton, EY; van Dorp, EL; Waxman, AR | 1 |
| Baud, FJ; Chevillard, L; Mégarbane, B; Risède, P | 1 |
| Bergeron, A; Dicaire, C; Furtado, M; Garofolo, F; Mess, JN | 1 |
1 review(s) available for naltrexone and morphine-6-glucuronide
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
17 other study(ies) available for naltrexone and morphine-6-glucuronide
| Article | Year |
|---|---|
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Opioid receptor agonist potencies of morphine and morphine-6-glucuronide in the guinea-pig ileum.
Topics: Amino Acid Sequence; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Molecular Sequence Data; Morphine; Morphine Derivatives; Muscle Contraction; Muscle, Smooth; Naltrexone; Peptide Fragments; Peptides; Receptors, Opioid; Receptors, Opioid, mu; Somatostatin | 1994 |
Differential effects of morphine-6-glucuronide, an active metabolite of morphine, and morphine on locomotor activity in mice: involvement of the opioid receptor.
Topics: Animals; Injections, Subcutaneous; Locomotion; Male; Mice; Mice, Inbred Strains; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1996 |
3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist.
Topics: Analgesia; Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Heroin; Male; Mice; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Transfection; Tritium | 1997 |
Morphine-6-glucuronide-induced locomotor stimulation in mice: role of opioid receptors.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Derivatives; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1998 |
Comparison of the discriminative and antinociceptive effects of morphine and its glucuronide metabolites after central or systemic administration in the rat.
Topics: Analgesics, Opioid; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Morphine Derivatives; Naltrexone; Rats; Rats, Sprague-Dawley | 1998 |
Antagonism of heroin and morphine self-administration in rats by the morphine-6beta-glucuronide antagonist 3-O-methylnaltrexone.
Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Heroin; Injections, Subcutaneous; Male; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Rats, Wistar; Self Administration | 1999 |
Morphine-6 beta-glucuronide has a higher efficacy than morphine as a mu-opioid receptor agonist in the rat locus coeruleus.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Locus Coeruleus; Male; Membrane Potentials; Morphine; Morphine Derivatives; Naltrexone; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2000 |
Morphine-6beta-glucuronide modulates the expression of inducible nitric oxide synthase.
Topics: Animals; Dose-Response Relationship, Drug; Lipopolysaccharides; Liver; Lung; Male; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Inbred Lew; Spleen; Tissue Distribution | 2001 |
Opioid partial agonist effects of 3-O-methylnaltrexone in rhesus monkeys.
Topics: Adenylyl Cyclases; Animals; Cocaine; Discrimination Learning; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heroin; Heroin Dependence; Macaca mulatta; Male; Morphine; Morphine Derivatives; Naltrexone; Narcotics; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Self Administration | 2004 |
Effect of repeated administrations of heroin, naltrexone, methadone, and alcohol on morphine glucuronidation in the rat.
Topics: Animals; Ethanol; Heroin; Heroin Dependence; Male; Methadone; Microsomes, Liver; Morphine; Morphine Derivatives; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2005 |
Non-opioid induction of morphine-6-glucuronide synthesis is elicited by prolonged exposure of rat hepatocytes to heroin.
Topics: Analgesics, Opioid; Animals; Cell Separation; Cells, Cultured; Chromatography, High Pressure Liquid; Half-Life; Hepatocytes; Heroin; In Vitro Techniques; Male; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley | 2008 |
Differential effect of morphine and morphine-6-glucuronide on the control of breathing in the anesthetized cat.
Topics: Analgesics, Opioid; Anesthesia; Animals; Blood-Brain Barrier; Carbon Dioxide; Cats; Female; Male; Morphine; Morphine Derivatives; Naltrexone; Respiration | 2008 |
Morphine-6beta-glucuronide rapidly increases pain sensitivity independently of opioid receptor activity in mice and humans.
Topics: Adolescent; Adult; Animals; Dizocilpine Maleate; Female; Humans; Hyperalgesia; Male; Mice; Mice, Knockout; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Young Adult | 2009 |
Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats.
Topics: Animals; Blood Gas Analysis; Buprenorphine; Catheterization; Fentanyl; Lactic Acid; Male; Methadone; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Plethysmography, Whole Body; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Respiratory Insufficiency; Respiratory Mechanics | 2009 |
Impact of organic solvent additive on the integrity of plasma samples in bioanalysis by LC-MS/MS.
Topics: Chromatography, High Pressure Liquid; Humans; Lipids; Morphine; Morphine Derivatives; Naltrexone; Organic Chemicals; Pharmaceutical Preparations; Quality Control; Reference Standards; Solvents; Tandem Mass Spectrometry | 2013 |