naltrexone and metyrapone

naltrexone has been researched along with metyrapone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ikebuchi, H; Kawanishi, T; Nagamatsu, K; Ohno, Y; Takanaka, A; Terao, T1
Barr, CS; Heilig, M; Kakko, J; Lidström, J; Svanborg, KD; von Wachenfeldt, J1

Reviews

1 review(s) available for naltrexone and metyrapone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for naltrexone and metyrapone

ArticleYear
Mood and neuroendocrine response to a chemical stressor, metyrapone, in buprenorphine-maintained heroin dependence.
    Biological psychiatry, 2008, Jan-15, Volume: 63, Issue:2

    Topics: Adult; Affect; Asparagine; Buprenorphine; DNA Mutational Analysis; Drug Interactions; Enzyme Inhibitors; Female; Heroin Dependence; Humans; Hypothalamo-Hypophyseal System; Male; Metyrapone; Middle Aged; Naltrexone; Narcotic Antagonists; Pituitary-Adrenal System; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Time Factors

2008

Other Studies

4 other study(ies) available for naltrexone and metyrapone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparative evaluation of different pathways for the liver toxicity of morphine using freshly isolated hepatocytes.
    Biochemical pharmacology, 1988, Jul-15, Volume: 37, Issue:14

    Topics: Animals; Glutathione; Liver; Male; Metyrapone; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains

1988