naltrexone has been researched along with methyldopa in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| de Jong, W; Sweep, CG; van Duinkerken, E; van Giersbergen, PL; van Ree, JM; Wiegant, VM | 1 |
| de Jong, W; de Lang, H; Roording, P; Van Giersbergen, PL | 1 |
| de Jong, W; van Giersbergen, PL | 1 |
| Nijkamp, FP; Sitsen, JM | 1 |
| Farsang, C; Kunos, G; Mucci, L; Ramirez-Gonzalez, MD | 1 |
| Kunos, G; Mosqueda Garcia, R; Ramirez-Gonzalez, MD; Tchakarov, L | 1 |
| Johnson, ML; Rogol, AD; Veldhuis, JD; Williams, FA | 1 |
| Dackis, CA; Gold, MS; Washton, AM | 1 |
2 review(s) available for naltrexone and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The sequential use of clonidine and naltrexone in the treatment of opiate addicts.
Topics: Adult; Baclofen; Clonidine; Drug Therapy, Combination; Electric Stimulation Therapy; Endorphins; Ethanol; Female; Humans; Locus Coeruleus; Male; Methyldopa; Naloxone; Naltrexone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1984 |
15 other study(ies) available for naltrexone and methyldopa
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Alpha-methyldopa induces a naltrexone-insensitive antinociception and hypomotility in rats.
Topics: Analgesics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endorphins; Male; Methyldopa; Motor Activity; Naltrexone; Radioimmunoassay; Rats; Rats, Inbred Strains; Reaction Time | 1990 |
Participation of opiate receptors located in the nucleus tractus solitarii in the hypotension induced by alpha-methyldopa.
Topics: Animals; Endorphins; Hypotension; Immune Sera; Medulla Oblongata; Methyldopa; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1989 |
Antagonism by naltrexone of the hypotension and bradycardia induced by alpha-methyldopa in conscious normotensive rats.
Topics: Animals; beta-Endorphin; Bradycardia; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Immune Sera; Male; Methyldopa; Naloxone; Naltrexone; Rats; Rats, Inbred Strains | 1988 |
Is the hypothermic effect of alpha-methyldopa mediated by opioid peptides?
Topics: Animals; Body Temperature; Endorphins; Male; Methyldopa; Morphine; Naltrexone; Rats; Rats, Inbred Strains | 1984 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Heart Rate; Hypertension; Male; Methyldopa; Morphine; Naloxone; Naltrexone; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Opioid; Time Factors; Yohimbine | 1980 |
beta-endorphin acting on the brainstem is involved in the antihypertensive action of clonidine and alpha-methyldopa in rats.
Topics: Animals; beta-Endorphin; Blood Pressure; Clonidine; Desoxycorticosterone; Endorphins; Heart Rate; Hypertension; Hypertension, Renal; Immune Sera; Male; Methyldopa; Naltrexone; Rats; Rats, Inbred Strains; Rats, Mutant Strains | 1983 |
Do alpha-adrenergic mechanisms regulate spontaneous or opiate-modulated pulsatile luteinizing hormone secretion in man?
Topics: Adult; Humans; Luteinizing Hormone; Male; Methyldopa; Naltrexone; Phenoxybenzamine; Receptors, Adrenergic, alpha; Receptors, Opioid | 1983 |