Compounds > naltrexone

naltrexone and methocinnamox

naltrexone has been researched along with methocinnamox in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Broadbear, J; Carrington, S; Husbands, SM; Lewis, JW; Moynihan, HA; Nieland, NP; Traynor, JR; Woods, JH1
Aschenbach, LC; Dewey, WL; Elbegdorj, O; Li, G; Scoggins, KL; Selley, DE; Stevens, DL; Yuan, Y; Zaidi, SA; Zhang, Y1
Broadbear, JH; Burke, TF; Husbands, SM; Lewis, JW; Sumpter, TL; Traynor, JR; Woods, JH1
Disney, A; France, CP; Gerak, LR; Husbands, SM; Maguire, DR; Woods, JH1
Disney, A; France, CP; Gerak, LR; Husbands, SM; Javors, MA; Maguire, DR; Sanchez, JJ1

Other Studies

5 other study(ies) available for naltrexone and methocinnamox

ArticleYear
Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effect of substitution in the aromatic ring of cinnamoylaminomorphinones and codeinones.
    Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17

    Topics: Cinnamates; Codeine; Drug Design; Ligands; Molecular Structure; Morphine Derivatives; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship

2006
Design, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivity.
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: Animals; Behavior, Animal; Chemistry Techniques, Synthetic; CHO Cells; Cricetinae; Cricetulus; Drug Design; Male; Mice; Models, Molecular; Naltrexone; Protein Conformation; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substrate Specificity

2013
Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Cerebral Cortex; Cinnamates; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Mice; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Pain Measurement; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2000
Long-Lasting Effects of Methocinnamox on Opioid Self-Administration in Rhesus Monkeys.
    The Journal of pharmacology and experimental therapeutics, 2019, Volume: 368, Issue:1

    Topics: Analgesics, Opioid; Animals; Cinnamates; Drug-Seeking Behavior; Female; Macaca mulatta; Male; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Self Administration; Time Factors

2019
Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:12

    Topics: Analgesics, Opioid; Animals; Cinnamates; Dose-Response Relationship, Drug; Fentanyl; Macaca mulatta; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Self Administration

2020