naltrexone and meperidine

naltrexone has been researched along with meperidine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's3 (17.65)18.2507
2000's6 (35.29)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Jolivette, LJ; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Cheney, DL; Costa, E; Racagni, G; Zsilla, G1
Barsan, WG; Bartlett, R; Bryan, C; Buncher, R; Danzl, DF; Ling, LJ; Seger, D1
Carino, MA; Horita, A; Yamawaki, S1
Herling, S; Solomon, RE; Valentino, RJ; Woods, JH1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH1
Cox, BM; Izenwasser, S; Katz, JL; Newman, AH1
Dykstra, LA; Hughes, CE1
Holtzman, SG1
Holtzman, SG; White, DA2

Reviews

2 review(s) available for naltrexone and meperidine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for naltrexone and meperidine

ArticleYear
Duration of antagonistic effects of nalmefene and naloxone in opiate-induced sedation for emergency department procedures.
    The American journal of emergency medicine, 1989, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Aged; Attention; Consciousness; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Male; Meperidine; Middle Aged; Multicenter Studies as Topic; Naloxone; Naltrexone; Random Allocation

1989

Other Studies

14 other study(ies) available for naltrexone and meperidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Correlation between analgesia and the decrease of acetylcholine turnover rate in cortex and hippocampus elicited by morphine, meperidine, viminol R2 and azidomorphine.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:3

    Topics: Acetylcholine; Analgesia; Animals; Cerebral Cortex; Corpus Striatum; Depression, Chemical; Ethanolamines; Hippocampus; Kinetics; Male; Meperidine; Morphine; Morphine Derivatives; Naltrexone; Rats

1976
Analeptic effect of opiate receptor agonists in rabbits.
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex

1985
Narcotic discrimination in pigeons: antagonism by naltrexone.
    European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2

    Topics: Animals; Columbidae; Cyclazocine; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethylketocyclazocine; Meperidine; Morphine; Naloxone; Naltrexone; Narcotics

1984
Narcotic discrimination in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity

1980
The cocaine-like behavioral effects of meperidine are mediated by activity at the dopamine transporter.
    European journal of pharmacology, 1996, Feb-15, Volume: 297, Issue:1-2

    Topics: Animals; Behavior, Animal; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Meperidine; Models, Molecular; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Saimiri

1996
Antagonism of the response rate-decreasing effects of meperidine and morphine by beta-funaltrexamine and naltrexone in squirrel monkeys.
    Drug and alcohol dependence, 1997, May-02, Volume: 45, Issue:3

    Topics: Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Feeding Behavior; Longitudinal Studies; Male; Meperidine; Morphine; Naltrexone; Narcotic Antagonists; Reinforcement, Psychology; Saimiri

1997
Antagonism of morphine-like discriminative effects by beta-funaltrexamine.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Cisterna Magna; Discrimination Learning; Fentanyl; Injections; Male; Meperidine; Morphine; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1997
Acute opioid pretreatment potentiates naltrexone-induced drinking suppression in water-deprived rats.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Analgesics, Opioid; Animals; Area Under Curve; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Fentanyl; Male; Meperidine; Morphine; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Water Deprivation

2001
Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey: a further characterization.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Diprenorphine; Discrimination, Psychological; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Generalization, Stimulus; Male; Meperidine; Mice; Morphine; Nalbuphine; Nalorphine; Naltrexone; Narcotic Antagonists; Saimiri; Water Deprivation

2005