naltrexone and memantine

naltrexone has been researched along with memantine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's7 (63.64)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bespalov, A; Danysz, W; Kashkin, V; Malyshkin, A; Neznanova, O; Sukhotina, I; Zakharova, E1
Kuzmin, A; Liljequist, S; Stenback, T1
Bristow, RE; Grahame, NJ; Heighton, ME; Oberlin, BG1
Bisaga, A; Carpenter, KM; Cheng, WY; Levin, FR; Mariani, JJ; Nunes, EV; Raby, WN; Sullivan, MA1
Cavallo, DA; Franco, N; Gueorguieva, R; Krishnan-Sarin, S; Krystal, JH; O'Malley, SS; Pittman, B; Shi, J; Tetrault, JM1
Brown, JN; Elias, AM; Pepin, MJ1

Reviews

2 review(s) available for naltrexone and memantine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Adjunctive memantine for opioid use disorder treatment: A systematic review.
    Journal of substance abuse treatment, 2019, Volume: 107

    Topics: Analgesics, Opioid; Buprenorphine; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Humans; Memantine; Methadone; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Outcome Assessment, Health Care; Substance Withdrawal Syndrome

2019

Trials

2 trial(s) available for naltrexone and memantine

ArticleYear
A placebo controlled trial of memantine as an adjunct to oral naltrexone for opioid dependence.
    Drug and alcohol dependence, 2011, Dec-01, Volume: 119, Issue:1-2

    Topics: Adult; Disease Progression; Dopamine Agents; Double-Blind Method; Female; Humans; Male; Medication Adherence; Memantine; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Placebos; Receptors, N-Methyl-D-Aspartate; Secondary Prevention; Substance Abuse Detection; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome; Young Adult

2011
Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2020, Volume: 45, Issue:2

    Topics: Adult; Alcohol Drinking; Cross-Over Studies; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Humans; Male; Memantine; Naltrexone; Narcotic Antagonists; Young Adult

2020

Other Studies

7 other study(ies) available for naltrexone and memantine

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats.
    Behavioural pharmacology, 2004, Volume: 15, Issue:4

    Topics: Acamprosate; Animals; Choice Behavior; Ethanol; Male; Memantine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taurine

2004
Memantine enhances the inhibitory effects of naltrexone on ethanol consumption.
    European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3

    Topics: Alcohol Drinking; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Male; Memantine; Models, Animal; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Self Administration

2008
Pharmacologic dissociation between impulsivity and alcohol drinking in high alcohol preferring mice.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:8

    Topics: Alcohol Drinking; Alcoholism; Amphetamine; Animals; Behavior, Addictive; Choice Behavior; Female; Impulsive Behavior; Male; Memantine; Mice; Naltrexone; Reaction Time

2010