naltrexone has been researched along with loperamide in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Linseman, MA | 1 |
| Bansinath, M; Bhargava, HN | 1 |
| Bryant, HU; Kuta, CC; Story, JA; Yim, GK | 1 |
| Maas, CL; van Duin, CT; van Miert, AS | 1 |
| Kromer, W | 1 |
| Lê, AD; Linseman, MA | 1 |
| Pol, O; Puig, MM | 1 |
| Lutz, EA; Shannon, HE | 1 |
| Andoh, T; Kuraishi, Y; Nakashima, Y; Sasaki, A; Shiraki, K; Takasaki, I | 1 |
| Labuz, D; Machelska, H; Mousa, SA; Schäfer, M; Stein, C | 1 |
| Butelman, ER; Chait, BT; Kreek, MJ; Mandau, M; Reed, B; Yuferov, V | 1 |
| Butelman, ER; Kreek, MJ; Prisinzano, TE; Rus, S; Simpson, DS; Wolf, A | 1 |
| Bidlack, JM; Dean, RL; Deaver, DR; Eyerman, D; Todtenkopf, MS; Turncliff, RZ | 1 |
| Carteret, AF; Cheong, YK; Dong, X; Guan, Y; He, SQ; Perez, FM; Raja, SN; Shechter, R; Sweitzer, SM; Xu, Q; Yang, F | 1 |
| Kolbow, J; Maritz, MA; Modess, C; Oswald, S; Rey, H; Siegmund, W; Wegner, D; Weitschies, W | 1 |
| Kolbow, J; Siegmund, W; Weitschies, W | 1 |
| Heller, NM; Maher, DP; Walia, D | 1 |
| Barnett, BS; Suzuki, J; Ward, HB | 1 |
| Haigney, MCP; Kao, DP; Kleiman, RB; Klein, M; Krantz, MJ; Rudo, TJ; Stockbridge, N | 1 |
1 review(s) available for naltrexone and loperamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for naltrexone and loperamide
| Article | Year |
|---|---|
Extended-release but not immediate-release and subcutaneous methylnaltrexone antagonizes the loperamide-induced delay of whole-gut transit time in healthy subjects.
Topics: Adult; Antidiarrheals; Constipation; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Antagonism; Female; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Injections, Subcutaneous; Loperamide; Male; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Young Adult | 2016 |
21 other study(ies) available for naltrexone and loperamide
| Article | Year |
|---|---|
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Central vs. peripheral mediation of opioid effects on alcohol consumption in free-feeding rats.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Loperamide; Male; Morphine; Naltrexone; Narcotic Antagonists; Piperidines; Polysorbates; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Evidence for a peripheral action of thyrotropin releasing hormone on gastrointestinal transit in mice.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Drug Synergism; Gastrointestinal Transit; Loperamide; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Thiazolidines; Thyrotropin-Releasing Hormone | 1988 |
Stress- and morphine-induced elevations of plasma and tissue cholesterol in mice: reversal by naltrexone.
Topics: Animals; Aorta; Cholesterol; Female; Liver; Loperamide; Mice; Morphine; Naltrexone; Receptors, LDL; Stress, Physiological | 1988 |
Loperamide: evidence for a centrally mediated opioid effect on rumen motility in conscious goats and sheep.
Topics: Animals; Domperidone; Gastrointestinal Motility; Goats; Kinetics; Loperamide; Naltrexone; Narcotics; Piperidines; Rumen; Sheep | 1986 |
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline | 1995 |
Effects of opioids on the absorption of alcohol.
Topics: Analgesics, Opioid; Animals; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Gastrointestinal Agents; Injections, Intraperitoneal; Injections, Subcutaneous; Intestinal Absorption; Loperamide; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Wistar | 1997 |
Peripheral effects of opioids in a model of chronic intestinal inflammation in mice.
Topics: Animals; Antidiarrheals; Body Weight; Carbon Monoxide; Enteritis; Gastrointestinal Transit; Jejunum; Loperamide; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid | 1998 |
Comparison of the peripheral and central effects of the opioid agonists loperamide and morphine in the formalin test in rats.
Topics: Analgesics, Opioid; Animals; Antidiarrheals; Cisterna Magna; Dose-Response Relationship, Drug; Formaldehyde; Injections; Injections, Subcutaneous; Loperamide; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2002 |
Effects of loperamide on mechanical allodynia induced by herpes simplex virus type-1 in mice.
Topics: Analgesics, Opioid; Animals; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Tolerance; Female; Foot; Herpes Simplex; Herpesvirus 1, Human; Injections; Injections, Subcutaneous; Loperamide; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Physical Stimulation | 2007 |
Relative contribution of peripheral versus central opioid receptors to antinociception.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Gene Expression; Loperamide; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Pain; Receptors, Opioid | 2007 |
Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates.
Topics: Analgesics, Opioid; Animals; Antidiarrheals; beta-Endorphin; Biomarkers; Biotransformation; Dose-Response Relationship, Drug; Fentanyl; Injections, Intravenous; Loperamide; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Neurosecretory Systems; Polymorphism, Single Nucleotide; Receptors, Opioid, mu; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates.
Topics: Animals; Biomarkers; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Female; Furans; Loperamide; Macaca mulatta; Male; Naltrexone; Prolactin; Pyrones; Receptors, Opioid, mu | 2008 |
Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats.
Topics: Administration, Oral; Alcohol Deterrents; Alcohol Drinking; Animals; Animals, Outbred Strains; Baclofen; Behavior, Animal; Drug Synergism; Drug Therapy, Combination; GABA-B Receptor Agonists; Loperamide; Male; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2012 |
Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Blotting, Western; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Hyperalgesia; Immunohistochemistry; Ligation; Loperamide; Male; Naltrexone; Narcotic Antagonists; Phosphorylation; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord; Spinal Nerves | 2013 |
Rapid Tolerance to Constipating Effects of Loperamide in Healthy Subjects.
Topics: Constipation; Healthy Volunteers; Humans; Loperamide; Naltrexone | 2016 |
Suppression of Human Natural Killer Cells by Different Classes of Opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Anesthesia; Buprenorphine; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Fluoresceins; Humans; Immunosuppression Therapy; K562 Cells; Killer Cells, Natural; Loperamide; Methadone; Morphinans; Morphine; Naloxone; Naltrexone; Succinimides; Toll-Like Receptor 4; Tramadol | 2019 |
Rapid transition from methadone to buprenorphine using naltrexone-induced withdrawal: A case report.
Topics: Adult; Antidiarrheals; Antiemetics; Antipruritics; Buprenorphine; Clonidine; Deprescriptions; Drug Substitution; Female; Humans; Loperamide; Methadone; Methocarbamol; Muscle Relaxants, Central; Naltrexone; Narcotic Antagonists; Ondansetron; Opiate Substitution Treatment; Opioid-Related Disorders; Promethazine; Substance Withdrawal Syndrome; Sympatholytics | 2019 |
Ventricular Arrhythmias Associated With Over-the-Counter and Recreational Opioids.
Topics: Analgesics, Opioid; Arrhythmias, Cardiac; Buprenorphine; Diphenoxylate; Humans; Loperamide; Methadone; Naltrexone; Nonprescription Drugs | 2023 |