naltrexone has been researched along with lactic acid in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, LH; Faden, AI; James, TL; Lemke, M; Shirane, R; Weinstein, PR | 1 |
| Metzger, DL; Rogol, AD; Thompson, DL; Veldhuis, JD; Weltman, A; Weltman, JY | 1 |
| Johnston, P; Keep, RF; Mertz, M; Schultz, CH; Stern, SA; Wang, X; Zink, BJ | 1 |
| He, GA; Hou, HM; Liu, XJ | 1 |
| Darmawati, MY; Suhaida, MG; Yahya, IB | 1 |
| Ehrich, EW; Garbutt, JC; Gastfriend, DR; Kranzler, HR; Loewy, JW; O'Malley, SS; Pettinati, HM; Silverman, BL | 1 |
| Liu, Y; O'Neil, AG; Sunderland, VB | 1 |
| Dong, Q; Dunbar, JL; Ehrich, EW; Lasseter, KC; Silverman, BL; Turncliff, RZ | 1 |
| Gao, YL; Li, G; Wu, XG | 1 |
| Siegel, S | 1 |
| Baud, FJ; Chevillard, L; Mégarbane, B; Risède, P | 1 |
| Cheng, K; Morrissey, EM; Negus, SS; Rice, KC; Rosenberg, M | 1 |
| Akala, EO; Pan, G; Wiriyacoonkasem, P | 1 |
| Pagar, KP; Vavia, PR | 1 |
| Banks, ML; Bowers, MS; Carlezon, WA; Cheng, K; Leitl, MD; Negus, SS; Onvani, S; Rice, KC | 1 |
| Chi, Q; Li, M; Li, Y; Li, Z; Lin, W; Xie, X; Xing, C; Yang, Y; Yang, Z; Zhang, H | 1 |
| Andhariya, JV; Burgess, DJ; Choi, S; Shen, J; Wang, Y; Zou, Y | 2 |
| Otte, A; Park, K; Sharifi, F; Yoon, G | 1 |
| Otte, A; Park, K | 1 |
| Behrouzi, M; Dinarvand, R; Ghareh Sheikhlou, M; Goodarzi, N; Rouini, MR; Saghafian Larijani, R; Shabani Ravari, N; Varshochian, R | 1 |
2 trial(s) available for naltrexone and lactic acid
| Article | Year |
|---|---|
Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial.
Topics: Adult; Alcoholism; Double-Blind Method; Drug Carriers; Female; Humans; Injections, Intramuscular; Lactic Acid; Male; Microspheres; Middle Aged; Naltrexone; Narcotic Antagonists; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Psychotherapy, Brief | 2005 |
Single- and multiple-dose pharmacokinetics of long-acting injectable naltrexone.
Topics: Administration, Oral; Adolescent; Adult; Alcohol Deterrents; Area Under Curve; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Female; Half-Life; Humans; Injections; Lactic Acid; Male; Microspheres; Middle Aged; Naltrexone; Narcotic Antagonists; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sex Characteristics | 2006 |
20 other study(ies) available for naltrexone and lactic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Opiate-receptor antagonist improves metabolic recovery and limits neurochemical alterations associated with reperfusion after global brain ischemia in rats.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Brain Chemistry; Brain Ischemia; Fatty Acids, Nonesterified; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Naltrexone; Narcotic Antagonists; Rats; Reperfusion | 1990 |
Cholinergic and opioid involvement in release of growth hormone during exercise and recovery.
Topics: Adult; Blood Glucose; Endorphins; Exercise; Growth Hormone; Humans; Lactates; Lactic Acid; Male; Naltrexone; Oxygen Consumption; Parasympathetic Nervous System; Presynaptic Terminals; Pulmonary Gas Exchange; Pyridostigmine Bromide | 1993 |
Effects of ethanol and naltrexone in a model of traumatic brain injury with hemorrhagic shock.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Cardiac Output; Ethanol; Hydrogen-Ion Concentration; Hypercapnia; Intracranial Pressure; Lactic Acid; Naltrexone; Narcotic Antagonists; Oxygen Consumption; Respiration; Shock, Hemorrhagic; Swine; Veins | 2001 |
Naltrexone microspheres: in vitro release and effect on morphine analgesia in mice.
Topics: Analgesia; Animals; Delayed-Action Preparations; Female; Lactic Acid; Mice; Microspheres; Morphine; Naltrexone; Narcotic Antagonists; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2001 |
Preparation of naltrexone hydrochloride loaded poly (DL-lactide-co-glycolide) microspheres and the effect of polyvinyl alcohol (PVA) as surfactant on the characteristics of the microspheres.
Topics: Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Glycolates; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Naltrexone; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Structure-Activity Relationship; Surface-Active Agents | 2004 |
In vitro and in vivo release of naltrexone from biodegradable depot systems.
Topics: Animals; Biodegradation, Environmental; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactic Acid; Microspheres; Naltrexone; Particle Size; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Solubility; Technology, Pharmaceutical | 2006 |
Optimization of the preparation of nalmefene-loaded sustained-release microspheres using central composite design.
Topics: Delayed-Action Preparations; Drug Design; Forecasting; Glycolates; Lactic Acid; Microspheres; Models, Theoretical; Naltrexone; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2006 |
Extended-release intramuscular naltrexone: a viewpoint by Steven Siegel.
Topics: Alcoholism; Delayed-Action Preparations; Humans; Injections, Intramuscular; Lactic Acid; Microspheres; Naltrexone; Narcotic Antagonists; Patient Compliance; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Treatment Outcome | 2006 |
Characteristics and comparative severity of respiratory response to toxic doses of fentanyl, methadone, morphine, and buprenorphine in rats.
Topics: Animals; Blood Gas Analysis; Buprenorphine; Catheterization; Fentanyl; Lactic Acid; Male; Methadone; Morphine; Morphine Derivatives; Naltrexone; Narcotic Antagonists; Narcotics; Plethysmography, Whole Body; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Respiratory Insufficiency; Respiratory Mechanics | 2009 |
Effects of kappa opioids in an assay of pain-depressed intracranial self-stimulation in rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Benzeneacetamides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Lactic Acid; Male; Medial Forebrain Bundle; Morphine; Naltrexone; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Stimulation | 2010 |
Studies on in vitro availability, degradation, and thermal properties of naltrexone-loaded biodegradable microspheres.
Topics: Alcoholism; Chromatography, Gel; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Lactic Acid; Microspheres; Molecular Weight; Naltrexone; Narcotic Antagonists; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Temperature; Time Factors; Transition Temperature | 2011 |
Naltrexone-loaded poly[La-(Glc-Leu)] polymeric microspheres for the treatment of alcohol dependence: in vitro characterization and in vivo biocompatibility assessment.
Topics: Alcoholism; Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Emulsions; Lactic Acid; Leucine; Microspheres; Naltrexone; Particle Size; Polyglycolic Acid; Polymers; Rats; Rats, Wistar; Solvents | 2014 |
Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous κ-opioids.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Depression; Disease Models, Animal; Dopamine; Gene Expression Regulation; Ketoprofen; Lactic Acid; Male; Medial Forebrain Bundle; Morphine; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Self Stimulation; Time Factors | 2014 |
In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene.
Topics: Animals; Drug Carriers; Drug Liberation; Female; Guinea Pigs; Lactic Acid; Male; Materials Testing; Mice; Microspheres; Naltrexone; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2015 |
Accelerated in vitro release testing method for naltrexone loaded PLGA microspheres.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Drug Liberation; Drug Stability; Lactic Acid; Microspheres; Naltrexone; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reproducibility of Results; Temperature; Time Factors | 2017 |
Development of in vitro-in vivo correlation of parenteral naltrexone loaded polymeric microspheres.
Topics: Animals; Drug Carriers; Drug Liberation; Lactic Acid; Male; Microspheres; Models, Theoretical; Naltrexone; Narcotic Antagonists; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits | 2017 |
Continuous in-line homogenization process for scale-up production of naltrexone-loaded PLGA microparticles.
Topics: Lactic Acid; Microspheres; Naltrexone; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Transitioning from a lab-scale PLGA microparticle formulation to pilot-scale manufacturing.
Topics: Animals; Drug Carriers; Lactic Acid; Microspheres; Naltrexone; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2022 |
Engineered PLGA microspheres for extended-release of naltrexone:
Topics: Drug Carriers; Humans; Lactic Acid; Microspheres; Naltrexone; Particle Size; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |