naltrexone and ketamine

naltrexone has been researched along with ketamine in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (6.12)	18.7374
1990's	5 (10.20)	18.2507
2000's	10 (20.41)	29.6817
2010's	24 (48.98)	24.3611
2020's	7 (14.29)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bansinath, M; Puig, MM; Tang, CK; Turndorf, H; Warner, W	1
Gintautas, JG; Kraynack, BJ	1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH	1
Hein, DW; Herling, S; Woods, JH; Young, AM	1
Freye, E; Latasch, L	1
France, CP; Gerak, LR	1
Manara, AR; Merriman, RJ; Mills, IH; Park, GR	1
Bagley, JR; Brockunier, LL; France, CP; Gauthier, CA	1
Aguilar, R; Bailey, JE; Foerster, CR; Foerster, SH; Loria, DL	1
Brandt, MR; France, CP	1
Bush, M; Citino, SB; Grobler, D; Lance, W	1
Atkinson, MW; Blumer, ES; Gandolf, AR; Hull, B	1
Belger, A; Brush, L; D'Souza, DC; Gueorguieva, R; Krystal, JH; Madonick, S; Perry, E; Wray, Y	1
Freye, E; Latasch, L; Levy, JV	1
Bonney, I; Carr, DB; Klinowiecka, A; Kosson, D; Kosson, P; Lipkowski, AW; Mayzner-Zawadzka, E	1
Calle, PP; Georoff, TA; James, SB; Kalk, P; Martin-Flores, M	1
Chateauraynaud, J; Gavello-Baudy, S; Laboureyras, E; Laulin, JP; Le Roy, C; Simonnet, G	1
Hales, TG	1
Benedek, G; Farkas, I; Horvath, G; Joo, G; Kekesi, G; Petrovszki, Z; Tuboly, G	1
Kalk, P; Moore, RP; Rainwater, KL; Sykes, JM; Valitutto, MT	1
Duarte, ID; Pacheco, Dda F; Romero, TR	1
Garg, A; Kumar, P; Prakash, O; Sinha, P	1
Buck, RK; Fosgate, GT; Gerlach, C; Kästner, SBR; Kummrow, M; Meyer, LRC; Stegmann, GF; Zeiler, GE	1
Birnbaum, J; Blasey, C; Hawkins, J; Heifets, BD; Lyons, DM; Pankow, H; Pannu, J; Rodriguez, CI; Schatzberg, AF; Sudheimer, K; Williams, NR	1
Giancola, JB; Keighron, JD; Lin, SC; Newman, AH; Scaglione, A; Tanda, G; Zanettini, C	1
Hashimoto, K; Zhang, K	1
Krystal, JH; Petrakis, IL; Yoon, G	2
Amiaz, R	1
Blasey, C; Heifets, BD; Rodriguez, CI; Schatzberg, AF; Sudheimer, K; Williams, NR	1
Barnes, DE; Marton, T; Wallace, A; Woolley, JD	1
Aghaei, I; Bahramnejad, E; Dehpour, AR; Kazemi Roodsari, S; Rahimi, N	1
Kaplin, A; Wang, M	1
Bentzley, BS; Heifets, BD; Schatzberg, AF; Williams, NR	1
Bentzley, BS; Blasey, C; Hawkins, J; Heifets, BD; Lyons, DM; Schatzberg, AF; Sudheimer, KD; Williams, NR	1
Caliari, MV; de Almeida, DL; Duarte, IDG; Lima Romero, TR; Paiva-Lima, P; Petrocchi, JA; Queiroz-Junior, C	1
Chen, Y; Fu, C; Hu, R; Huang, C; Jiang, H; Li, C; Sun, Y; Tang, D; Wang, H; Yan, J; Zhu, J	1
Klein, ME; Malinow, R	1
Anderson, PM; Hillhouse, TM; Kegen, TN; Koppenhaver, PO; Lane, JT; Manicka, SG; Porter, JH; Pottanat, E; Rice, R; Van Fossen, M; Zhang, F	1
Browne, CA; Lucki, I; Wulf, HA; Zarate, CA	1
Anderson, NE; Delnatte, P; Dutton, C; Ferro, A; Larouche, CB; Milnes, EL; Skelding, AM	1
Cornell, A; Loh, R; Taub, J; Terasaki, D; Thurstone, C	1
Andale, T; Aruasa, WK; Gakinya, B; Jaguga, F; Kerema, J; Kinyanjui, D; Kirwa, P; Kwobah, C; Kwobah, EK; Manji, I; Mwangi, F; Songok, J; Temet, E; Werunga, K	1

Reviews

1 review(s) available for naltrexone and ketamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

7 trial(s) available for naltrexone and ketamine

Article	Year
Treatment of compulsive behaviour in eating disorders with intermittent ketamine infusions. QJM : monthly journal of the Association of Physicians, 1998, Volume: 91, Issue:7 Topics: Adult; Anesthetics, Dissociative; Anorexia; Chronic Disease; Compulsive Personality Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Ketamine; Memory; Naltrexone; Narcotic Antagonists; Treatment Outcome	1998
Potentiation of low dose ketamine effects by naltrexone: potential implications for the pharmacotherapy of alcoholism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:8 Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Double-Blind Method; Drug Synergism; Ethanol; Female; Humans; Ketamine; Male; Naltrexone; Receptors, N-Methyl-D-Aspartate	2006
Evaluation of medetomidine-ketamine-butorphanol anesthesia with atipamezole-naltrexone antagonism in captive male guanacos (Lama guanicoe). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2010, Volume: 41, Issue:2 Topics: Adrenergic alpha-Antagonists; Anesthetics; Animals; Butorphanol; Camelids, New World; Imidazoles; Ketamine; Male; Medetomidine; Naltrexone; Narcotic Antagonists	2010
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism. The American journal of psychiatry, 2018, 12-01, Volume: 175, Issue:12 Topics: Adult; Antidepressive Agents; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ketamine; Male; Naltrexone; Narcotic Antagonists; Psychiatric Status Rating Scales	2018
Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder. JAMA psychiatry, 2019, 03-01, Volume: 76, Issue:3 Topics: Adult; Alcohol Drinking; Alcoholism; Craving; Depressive Disorder, Major; Drug Therapy, Combination; Female; Humans; Ketamine; Male; Middle Aged; Naltrexone; Pilot Projects	2019
A randomized clinical trial to compare ketamine-butorphanol-azaperone-medetomidine and detomidine-etorphine-acepromazine for anesthesia of captive Przewalski horses (Equus przewalskii). American journal of veterinary research, 2022, May-08, Volume: 83, Issue:6 Topics: Acepromazine; Anesthesia; Animals; Azaperone; Butorphanol; Etorphine; Heart Rate; Horses; Hypnotics and Sedatives; Hypoxia; Imidazoles; Immobilization; Ketamine; Medetomidine; Naltrexone; Oxygen; Prospective Studies	2022
Single-dose intravenous ketamine or intramuscular naltrexone for high-utilization inpatients with alcohol use disorder: pilot trial feasibility and readmission rates. Addiction science & clinical practice, 2022, 11-22, Volume: 17, Issue:1 Topics: Adolescent; Adult; Aged; Alcoholism; Feasibility Studies; Humans; Inpatients; Ketamine; Middle Aged; Naltrexone; Patient Readmission; Pilot Projects; Young Adult	2022

Other Studies

41 other study(ies) available for naltrexone and ketamine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations	2002
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
On the mechanism of the interaction of ketamine and halothane in vitro. General pharmacology, 1992, Volume: 23, Issue:6 Topics: Animals; Drug Interactions; GTP-Binding Proteins; Guinea Pigs; Halothane; Ileum; In Vitro Techniques; Ketamine; Muscle, Smooth; Muscle, Smooth, Vascular; Myenteric Plexus; Naloxone; Naltrexone; Pertussis Toxin; Receptors, Opioid; Virulence Factors, Bordetella	1992
Naloxone: analeptic action unrelated to opiate receptor antagonism? Anesthesiology, 1982, Volume: 56, Issue:4 Topics: Animals; Central Nervous System Stimulants; Halothane; Injections, Intraventricular; Ketamine; Male; Naloxone; Naltrexone; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Opioid; Sleep	1982
Narcotic discrimination in pigeons. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1 Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity	1980
Pharmacological analysis of the discriminative stimulus characteristics of ethylketazocine in the rhesus monkey. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:1 Topics: Animals; Cyclazocine; Dextrorphan; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Macaca mulatta; Naltrexone; Narcotic Antagonists; Narcotics; Phencyclidine; Prejudice; Stereoisomerism	1981
Opioid receptors-mediated respiratory effects and antinociception after S(+)-ketamine. Acta anaesthesiologica Belgica, 1993, Volume: 44, Issue:3 Topics: Animals; Dogs; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Somatosensory; Ketamine; Naltrexone; Narcotic Antagonists; Nociceptors; Receptors, Opioid; Respiration; Stereoisomerism; Wakefulness	1993
Changes in sensitivity to the rate-decreasing effects of opioids in pigeons treated acutely or chronically with l-alpha-acetylmethadol. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2 Topics: Analgesics, Opioid; Animals; Columbidae; Dose-Response Relationship, Drug; Drug Tolerance; Ketamine; Methadyl Acetate; Naltrexone	1997
Daily mirfentanil induces (cross-) tolerance to the rate-decreasing effects of morphine and not mirfentanil. Behavioural pharmacology, 1999, Volume: 10, Issue:5 Topics: Analgesics; Animals; Arousal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Fentanyl; Ketamine; Morphine; Naltrexone	1999
Butorphanol/xylazine/ketamine immobilization of free-ranging Baird's tapirs in Costa Rica. Journal of wildlife diseases, 2000, Volume: 36, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Animals, Wild; Blood Gas Analysis; Blood Pressure; Butorphanol; Costa Rica; Electrocardiography; Female; Heart Rate; Immobilization; Ketamine; Male; Naltrexone; Narcotic Antagonists; Oximetry; Perissodactyla; Respiration; Tolazoline; Xylazine; Yohimbine	2000
Chronic l-alpha-acetylmethadol (LAAM) in rhesus monkeys: tolerance and cross-tolerance to the antinociceptive, ventilatory, and rate-decreasing effects of opioids. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Analgesics, Opioid; Animals; Drug Tolerance; Dynorphins; Female; Ketamine; Macaca mulatta; Male; Methadyl Acetate; Nalbuphine; Naltrexone; Narcotics; Respiration	2000
Anesthesia of boma-captured Lichtenstein's hartebeest (Sigmoceros lichtensteinii) with a combination of thiafentanil, medetomidine, and ketamine. Journal of wildlife diseases, 2002, Volume: 38, Issue:2 Topics: Adrenergic alpha-Agonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Antelopes; Drug Synergism; Female; Fentanyl; Ketamine; Male; Medetomidine; Naltrexone; Narcotic Antagonists	2002
Repeated chemical immobilization of a captive greater one-horned rhinoceros (Rhinoceros unicornis), using combinations of etorphine, detomidine, and ketamine. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:2 Topics: Anesthetics, Dissociative; Animals; Body Temperature; Drug Combinations; Etorphine; Heart Rate; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Naltrexone; Narcotic Antagonists; Oximetry; Perissodactyla; Respiration; Time Factors	2002
S(+)-ketamine attenuates increase in electroencephalograph activity and amplitude height of sensory-evoked potentials during rapid opioid detoxification. Anesthesia and analgesia, 2006, Volume: 102, Issue:5 Topics: Adult; Electroencephalography; Evoked Potentials, Somatosensory; Female; Humans; Ketamine; Male; Middle Aged; Naltrexone; Opioid-Related Disorders	2006
Intrathecal antinociceptive interaction between the NMDA antagonist ketamine and the opioids, morphine and biphalin. European journal of pain (London, England), 2008, Volume: 12, Issue:5 Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Drug Synergism; Drug Therapy, Combination; Drug Tolerance; Enkephalins; Excitatory Amino Acid Antagonists; Hot Temperature; Injections, Spinal; Ketamine; Male; Morphine; Naltrexone; Narcotics; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Tail	2008
Endogenous opioids released during non-nociceptive environmental stress induce latent pain sensitization Via a NMDA-dependent process. The journal of pain, 2011, Volume: 12, Issue:10 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Carrageenan; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fentanyl; Hyperalgesia; Inflammation; Ketamine; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Swimming; Time Factors	2011
Arresting the development of morphine tolerance and dependence. British journal of anaesthesia, 2011, Volume: 107, Issue:5 Topics: Analgesics; Animals; Drug Tolerance; Humans; Ketamine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Ondansetron; Pain; Polypharmacy; Quaternary Ammonium Compounds; Serotonin Antagonists	2011
Inhibition of itch-related responses at spinal level in rats. Acta physiologica Hungarica, 2011, Volume: 98, Issue:4 Topics: 5-Methoxytryptamine; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Naltrexone; Narcotic Antagonists; Pruritus; Rats; Rats, Wistar; Spinal Cord	2011
Comparison of two injectable immobilization combinations in Himalayan tahr (Hemitragus jemlahicus): medetomidine, ketamine, and atipamezole versus carfentanil, xylazine, naltrexone, and atipamezole. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2013, Volume: 44, Issue:3 Topics: Animals; Fentanyl; Hypnotics and Sedatives; Imidazoles; Ketamine; Medetomidine; Naltrexone; Ruminants; Xylazine	2013
Central antinociception induced by ketamine is mediated by endogenous opioids and μ- and δ-opioid receptors. Brain research, 2014, May-08, Volume: 1562 Topics: Aminopeptidases; Analgesics; Animals; Brain; Cinnamates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hot Temperature; Ketamine; Leucine; Male; Mice; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptive Pain; Opioid Peptides; Pain Perception; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2014
Use of naltrexone in ketamine dependence. Addictive behaviors, 2014, Volume: 39, Issue:8 Topics: Adult; Craving; Humans; Ketamine; Male; Naltrexone; Narcotic Antagonists; Substance Abuse, Intravenous; Substance Withdrawal Syndrome; Treatment Outcome	2014
Propofol-medetomidine-ketamine total intravenous anaesthesia in thiafentanil-medetomidine-immobilized impala (Aepyceros melampus). Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Intravenous; Anesthetics, Combined; Animals; Antelopes; Female; Fentanyl; Heart Rate; Hypnotics and Sedatives; Imidazoles; Ketamine; Medetomidine; Naltrexone; Narcotic Antagonists; Propofol; Prospective Studies; Respiratory Rate	2017
Pharmacological classification of centrally acting drugs using EEG in freely moving rats: an old tool to identify new atypical dopamine uptake inhibitors. Neuropharmacology, 2019, 12-15, Volume: 161 Topics: Animals; Central Nervous System Agents; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Electroencephalography; Heroin; Ketamine; Male; Methylphenidate; Modafinil; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu	2019
Lack of Opioid System in the Antidepressant Actions of Ketamine. Biological psychiatry, 2019, 03-15, Volume: 85, Issue:6 Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Ketamine; Lipopolysaccharides; Male; Mice; Naltrexone; Stress, Psychological	2019
Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism: Is It a Ketamine-Specific Effect? The American journal of psychiatry, 2019, 03-01, Volume: 176, Issue:3 Topics: Antidepressive Agents; Ketamine; Naltrexone; Narcotic Antagonists; Receptors, Opioid	2019
Target Population, Dose, and Timing Considerations for Understanding Naltrexone's Subjective Effect: Response to Amiaz. The American journal of psychiatry, 2019, 03-01, Volume: 176, Issue:3 Topics: Alcohol Drinking; Alcoholism; Antidepressive Agents; Humans; Ketamine; Naltrexone; Narcotic Antagonists; Population; Receptors, Opioid	2019
Concurrent Use of Buprenorphine, Methadone, or Naltrexone Does Not Inhibit Ketamine's Antidepressant Activity. Biological psychiatry, 2019, 06-15, Volume: 85, Issue:12 Topics: Adult; Aged; Analgesics, Opioid; Antidepressive Agents; Buprenorphine; Depressive Disorder, Treatment-Resistant; Female; Humans; Ketamine; Male; Methadone; Middle Aged; Naltrexone; Treatment Outcome	2019
Methadone's effects on pentylenetetrazole-induced seizure threshold in mice: NMDA/opioid receptors and nitric oxide signaling. Annals of the New York Academy of Sciences, 2019, Volume: 1449, Issue:1 Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Guanidines; Indazoles; Ketamine; Male; Methadone; Mice; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Seizures	2019
Explaining Naltrexone's Interference With Ketamine's Antidepressant Effect. The American journal of psychiatry, 2019, 05-01, Volume: 176, Issue:5 Topics: Antidepressive Agents; Ketamine; Naltrexone; Narcotic Antagonists; Receptors, Opioid	2019
Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect-Reply. JAMA psychiatry, 2019, 06-01, Volume: 76, Issue:6 Topics: Alcoholism; Antidepressive Agents; Depression; Humans; Ketamine; Naltrexone; Receptors, Opioid	2019
Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect. JAMA psychiatry, 2019, 06-01, Volume: 76, Issue:6 Topics: Alcoholism; Antidepressive Agents; Depression; Humans; Ketamine; Naltrexone; Receptors, Opioid	2019
Attenuation of antidepressant and antisuicidal effects of ketamine by opioid receptor antagonism. Molecular psychiatry, 2019, Volume: 24, Issue:12 Topics: Adult; Antidepressive Agents; Cross-Over Studies; Depressive Disorder, Treatment-Resistant; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Psychiatric Status Rating Scales; Receptors, Opioid; Suicidal Ideation; Suicide; Treatment Outcome	2019
Peripheral antinociception induced by ketamine is mediated by the endogenous opioid system. European journal of pharmacology, 2019, Dec-15, Volume: 865 Topics: Analgesics; Animals; Cinnamates; Dinoprostone; Ketamine; Male; Mice; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu	2019
GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats. Scientific reports, 2020, 03-24, Volume: 10, Issue:1 Topics: Adjuvants, Anesthesia; Allosteric Regulation; Analgesia; Anesthesia; Animals; Delayed Emergence from Anesthesia; Dexmedetomidine; Drug Combinations; Drug Evaluation, Preclinical; Female; Fentanyl; Flumazenil; GABA-A Receptor Antagonists; Ketamine; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nociception; Pain Measurement; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Rotarod Performance Test	2020
Reply to Hashimoto: Ketamine is not an opioid but requires opioid system for antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-26, Volume: 117, Issue:21 Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Ketamine; Naltrexone; Rodentia	2020
Opioid receptor system contributes to the acute and sustained antidepressant-like effects, but not the hyperactivity motor effects of ketamine in mice. Pharmacology, biochemistry, and behavior, 2021, Volume: 208 Topics: Anesthetics, Dissociative; Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Female; Hindlimb Suspension; Ketamine; Locomotion; Male; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Psychomotor Agitation; Receptors, Opioid	2021
Mediation of the behavioral effects of ketamine and (2R,6R)-hydroxynorketamine in mice by kappa opioid receptors. Psychopharmacology, 2022, Volume: 239, Issue:7 Topics: Animals; Behavior, Animal; Depressive Disorder, Major; Humans; Ketamine; Mice; Naltrexone; Receptors, Opioid, kappa	2022
Intravenous ketamine for severe alcohol use disorder at Moi Teaching & Referral Hospital, Kenya: a case report. Substance abuse treatment, prevention, and policy, 2023, 02-17, Volume: 18, Issue:1 Topics: Adult; Alcoholism; Hospitals; Humans; Kenya; Ketamine; Male; Naltrexone; Referral and Consultation; Smoking Cessation; Tobacco Use Cessation Devices	2023