naltrexone and indomethacin

naltrexone has been researched along with indomethacin in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's2 (8.33)18.2507
2000's13 (54.17)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Guglietta, A; Irons, BJ; Lazarus, LH; Sivam, SP1
Ferreira, SH; Follenfant, RL; Smith, TW1
Gallo, RV; Zhen, S1
Gannon, GA; Rhind, SG; Sabiston, BH; Shek, PN; Shephard, RJ; Suzui, M; Zamecnik, J1
Kagaya, A; Kouhata, S; Nakae, S; Nakata, Y; Yamawaki, S1
Kowalczyk, M; Lapo, I; Massi, M; Panocka, I; Sadowski, B; Swiderski, T1
Armstead, WM; Kulkarni, M1
Faletti, AG; Farina, M; Lomniczi, A; Mohn, C; Rettori, V1
Bakhle, YS; Duarte, ID; Ferreira-Alves, DL; França, DS; Francischi, JN; Rezende, RM; Ribeiro, MC1
Ceballos-Reyes, G; Granados-Soto, V; Jiménez-Andrade, GY; Reyes-García, G; Sereno, G; Vidal-Cantú, GC1
Beck, P; Bonacorso, HG; Drewes, C; Ferreira, J; Machado, P; Martins, MA; Mello, CF; Milano, J; Oliveira, SM; Rossato, MF; Rubin, MA; Zanatta, N1
Abdel-Salam, LO; Kamel, MM; Khattab, A; Osman, AS; Tawfik, DI; Tolba, HM1

Reviews

3 review(s) available for naltrexone and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for naltrexone and indomethacin

ArticleYear
beta-Endorphin and natural killer cell cytolytic activity during prolonged exercise. is there a connection?
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Adult; Antigens, CD; beta-Endorphin; Cell Adhesion Molecules; Double-Blind Method; Humans; Indomethacin; Killer Cells, Natural; Lymphocyte Count; Male; Monocytes; Naltrexone; Narcotic Antagonists; Neurosecretory Systems; Physical Exertion; Time Factors

1998

Other Studies

20 other study(ies) available for naltrexone and indomethacin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effects and mechanism of action of lithium chloride on gastric acid secretion in rats.
    Gastroenterology, 1988, Volume: 95, Issue:6

    Topics: Animals; Brain; Chlorides; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Gastric Acid; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Lithium; Lithium Chloride; Male; Naltrexone; Rats; Time Factors

1988
Antinociceptive models displaying peripheral opioid activity.
    International journal of tissue reactions, 1985, Volume: 7, Issue:1

    Topics: Analgesics; Animals; Carrageenan; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Epoprostenol; Female; Indomethacin; Mice; Morphine; Movement; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists

1985
The role of norepinephrine in mediating luteinizing hormone release in response to blockade of kappa-opioid receptors in the medial preoptic area.
    Brain research, 1995, Nov-06, Volume: 698, Issue:1-2

    Topics: Animals; Basal Metabolism; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Female; Indomethacin; Luteinizing Hormone; Naltrexone; Norepinephrine; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Secretory Rate

1995
Effect of acute lipopolysaccharide administration on (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2 aminopropane-induced wet dog shake behavior in rats: comparison with body weight change and locomotor activity.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:2

    Topics: Amphetamines; Animals; Body Weight; Drug Administration Schedule; Endotoxins; Indomethacin; Lipopolysaccharides; Male; Motor Activity; Naltrexone; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Salmonella typhimurium; Serotonin Receptor Agonists; Stereotyped Behavior; Tumor Necrosis Factor-alpha

2001
Antidepressant-type effect of the NK3 tachykinin receptor agonist aminosenktide in mouse lines differing in endogenous opioid system activity.
    Peptides, 2001, Volume: 22, Issue:7

    Topics: Analgesia; Animals; Antidepressive Agents; Behavior, Animal; Cell Line; Dose-Response Relationship, Drug; Female; Indomethacin; Male; Mice; Naltrexone; Narcotics; Peptide Fragments; Receptors, Tachykinin; Substance P; Swimming

2001
Relationship between NOC/oFQ, dynorphin, and COX-2 activation in impaired NMDA cerebrovasodilation after brain injury.
    Journal of neurotrauma, 2002, Volume: 19, Issue:8

    Topics: Animals; Animals, Newborn; Brain Injuries; Cyclooxygenase 2; Dynorphins; Enzyme Activation; Female; Glutamic Acid; Indomethacin; Isoenzymes; Male; N-Methylaspartate; Naltrexone; Nitrobenzenes; Nociceptin; Opioid Peptides; Pia Mater; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Superoxides; Swine; Vasodilation

2002
Interaction among beta-endorphin, nitric oxide and prostaglandins during ovulation in rats.
    Reproduction (Cambridge, England), 2003, Volume: 125, Issue:4

    Topics: Animals; beta-Endorphin; Blotting, Western; Chorionic Gonadotropin; Dinoprostone; Female; Indomethacin; Meloxicam; Models, Animal; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovary; Ovulation; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles

2003
Endogenous opioids mediate the hypoalgesia induced by selective inhibitors of cyclo-oxygenase 2 in rat paws treated with carrageenan.
    Neuropharmacology, 2006, Volume: 51, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Animals; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Tolerance; Edema; Endorphins; Foot; Hyperalgesia; Indomethacin; Injections; Injections, Subcutaneous; Male; Morphine; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Signal Transduction; Species Specificity

2006
Pyritinol reduces nociception and oxidative stress in diabetic rats.
    European journal of pharmacology, 2008, Aug-20, Volume: 590, Issue:1-3

    Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Female; Indomethacin; Naltrexone; Oxadiazoles; Oxidative Stress; Pyrithioxin; Quinoxalines; Rats; Rats, Wistar; Streptozocin

2008
Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice.
    Life sciences, 2008, Nov-21, Volume: 83, Issue:21-22

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dipyrone; Freund's Adjuvant; Indomethacin; Inflammation; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain, Postoperative; Postural Balance; Pyrazoles; Stomach Ulcer

2008
Evaluation of therapeutic effect of low dose naltrexone in experimentally-induced Crohn's disease in rats.
    Neuropeptides, 2016, Volume: 59

    Topics: Animals; Crohn Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ileum; Indomethacin; Intestinal Mucosa; Male; Naltrexone; Narcotic Antagonists; Rats; Sulfasalazine; Treatment Outcome

2016