naltrexone and flumazenil

naltrexone has been researched along with flumazenil in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.33)	18.7374
1990's	12 (40.00)	18.2507
2000's	10 (33.33)	29.6817
2010's	6 (20.00)	24.3611
2020's	1 (3.33)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Carden, SE; Hofer, MA	3
Lenz, K; Loimer, N; Presslich, O; Schmid, R	1
Bilsky, EJ; Marglin, SH; Reid, LD	1
Insel, TR; Winslow, JT	1
Jackson, HC; Sewell, RD	1
Czech, DA	1
Fujimoto, JM; Holmes, BB; Rady, JJ	1
Brandt, MR; France, CP; Gerak, LR	1
Braselton, WE; Cook, RA; Dierenfeld, ES; House, C; Karesh, WB; Puche, H; Torres, A; Uhart, MM	1
Carson, RE; Endres, CJ	1
Courtière, A; Hardouin, J	1
Easterling, KW; Holtzman, SG; Plovnick, RM	1
Agrewala, JN; Kulkarni, SK; Raghavendra, V; Singh, V	1
Spelman, LH	1
Carai, MA; Colombo, G; Gessa, GL	1
McGregor, IS; van Nieuwenhuijzen, PS	1
Bienkowski, P; Kolaczkowski, M; Korkosz, A; Kostowski, W; Mierzejewski, P; Nowak, N; Samochowiec, J; Scinska, A; Sienkiewicz-Jarosz, H	1
Chen, Y; Fu, C; Hu, R; Huang, C; Jiang, H; Li, C; Sun, Y; Tang, D; Wang, H; Yan, J; Zhu, J	1
Arrazola, X; Gutiérrez-Fraile, M; Iraurgi, I; Jiménez-Lerma, JM; Landabaso, MA	1

Reviews

1 review(s) available for naltrexone and flumazenil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

29 other study(ies) available for naltrexone and flumazenil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations	2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
The effects of opioid and benzodiazepine antagonists on dam-induced reductions in rat pup isolation distress. Developmental psychobiology, 1990, Volume: 23, Issue:8 Topics: Animals; Arousal; Brain; Dose-Response Relationship, Drug; Female; Flumazenil; Male; Maternal Deprivation; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Social Isolation; Vocalization, Animal	1990
Rapid transition from methadone maintenance to naltrexone. Lancet (London, England), 1990, Jan-13, Volume: 335, Issue:8681 Topics: Flumazenil; Humans; Methadone; Midazolam; Naltrexone; Substance Withdrawal Syndrome	1990
Using antagonists to assess neurochemical coding of a drug's ability to establish a conditioned place preference. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3 Topics: Analgesics; Animals; Brain Chemistry; Conditioning, Operant; Flumazenil; Habituation, Psychophysiologic; Male; Morphine; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Scopolamine	1990
Independence of benzodiazepine and opiate action in the suppression of isolation distress in rat pups. Behavioral neuroscience, 1990, Volume: 104, Issue:1 Topics: Animals; Arousal; Chlordiazepoxide; Dose-Response Relationship, Drug; Flumazenil; Morphine; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Social Isolation; Vocalization, Animal	1990
Serotonergic and catecholaminergic reuptake inhibitors have opposite effects on the ultrasonic isolation calls of rat pups. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:1 Topics: Animals; Body Temperature; Catecholamines; Citalopram; Clomipramine; Desipramine; Flumazenil; Mazindol; Motor Activity; Naltrexone; Nortriptyline; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stress, Psychological; Ultrasonics; Vocalization, Animal	1990
Socially mediated reduction of isolation distress in rat pups is blocked by naltrexone but not by Ro 15-1788. Behavioral neuroscience, 1990, Volume: 104, Issue:3 Topics: Animals; Animals, Newborn; Arousal; Brain; Dose-Response Relationship, Drug; Flumazenil; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Opioid; Social Environment; Social Isolation; Vocalization, Animal	1990
The role of opioid receptor sub-types in tifluadom-induced feeding. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:10 Topics: Animals; Benzodiazepines; Benzodiazepinones; Benzomorphans; Convulsants; Eating; Enkephalin, Leucine; Flumazenil; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereoisomerism	1984
Nitrous oxide induces feeding in the nondeprived rat that is antagonized by naltrexone. Physiology & behavior, 1995, Volume: 58, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Male; Naltrexone; Nitrous Oxide; Rats	1995
Supraspinal flumazenil inhibits the antianalgesic action of spinal dynorphin A (1-17). Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1 Topics: Analgesia; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Flumazenil; GABA Agonists; GABA-A Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Physostigmine	1998
Studies on benzodiazepines and opioids administered alone and in combination in rhesus monkeys: ventilation and drug discrimination. Psychopharmacology, 1998, Volume: 137, Issue:2 Topics: Animals; Benzodiazepines; Discrimination Learning; Dose-Response Relationship, Drug; Drug Synergism; Female; Flumazenil; Macaca mulatta; Male; Midazolam; Morphine; Naltrexone; Narcotics; Respiration	1998
Health evaluation of free-ranging guanaco (Lama guanicoe). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1998, Volume: 29, Issue:2 Topics: Analgesics, Opioid; Anesthetics; Animals; Animals, Domestic; Animals, Wild; Antibodies; Antidotes; Blood Chemical Analysis; Camelids, New World; Communicable Diseases; Drug Combinations; Enzymes; Female; Fentanyl; Flumazenil; Health Status; Immobilization; Male; Minerals; Naltrexone; Narcotic Antagonists; Physical Examination; Reference Values; Sheep; Tiletamine; Vitamins; Zolazepam	1998
Assessment of dynamic neurotransmitter changes with bolus or infusion delivery of neuroreceptor ligands. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1998, Volume: 18, Issue:11 Topics: Brain; Carbon Radioisotopes; Computer Simulation; Dopamine; Dopamine Antagonists; Flumazenil; Humans; Infusions, Parenteral; Injections; Kinetics; Microdialysis; Models, Neurological; Naltrexone; Narcotic Antagonists; Raclopride; Radioligand Assay; Receptors, Dopamine; Salicylamides; Sensitivity and Specificity; Tomography, Emission-Computed	1998
Behavioural effects induced by nitrous oxide in rats performing a vigilance task. Behavioural pharmacology, 1997, Volume: 8, Issue:5 Topics: Animals; Attention; Flumazenil; GABA Modulators; Male; Naltrexone; Nitrous Oxide; Psychomotor Performance; Rats; Rats, Long-Evans; Receptors, GABA-A; Receptors, Opioid	1997
Acute opioid but not benzodiazepine dependence in rats responding for intracranial self-stimulation. Psychopharmacology, 2000, Volume: 148, Issue:3 Topics: Animals; Benzodiazepines; Brain; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Morphine; Naltrexone; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Stimulation; Substance-Related Disorders	2000
Melatonin enhances Th2 cell mediated immune responses: lack of sensitivity to reversal by naltrexone or benzodiazepine receptor antagonists. Molecular and cellular biochemistry, 2001, Volume: 221, Issue:1-2 Topics: Animals; Cell Line; Central Nervous System Agents; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Flumazenil; GABA-A Receptor Antagonists; Hybridomas; Immunoglobulin G; Isoquinolines; Melatonin; Mice; Mice, Inbred BALB C; Naltrexone; Narcotic Antagonists; Ovalbumin; Peripheral Nervous System Agents; Receptors, Opioid, mu; Th2 Cells	2001
Reversible anesthesia of captive California sea lions (Zalophus californianus) with medetomidine, midazolam, butorphanol, and isoflurane. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2004, Volume: 35, Issue:1 Topics: Anesthetics, Combined; Anesthetics, Inhalation; Animals; Antidotes; Butorphanol; Dose-Response Relationship, Drug; Female; Flumazenil; Heart Rate; Hypnotics and Sedatives; Imidazoles; Immobilization; Isoflurane; Medetomidine; Midazolam; Naltrexone; Narcotic Antagonists; Narcotics; Respiration; Sea Lions; Time Factors	2004
Resuscitative effect of a gamma-aminobutyric acid B receptor antagonist on gamma-hydroxybutyric acid mortality in mice. Annals of emergency medicine, 2005, Volume: 45, Issue:6 Topics: Animals; Benzocycloheptenes; Bicuculline; Drug Overdose; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Morpholines; Naltrexone; Neuroprotective Agents; Neurotransmitter Agents; Survival Rate; Taurine	2005
Sedative and hypothermic effects of gamma-hydroxybutyrate (GHB) in rats alone and in combination with other drugs: assessment using biotelemetry. Drug and alcohol dependence, 2009, Aug-01, Volume: 103, Issue:3 Topics: Animals; Baclofen; Benzazepines; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Flumazenil; Hypothermia; Illicit Drugs; Male; Methamphetamine; Morpholines; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Rats; Rats, Wistar; Ritanserin; Sodium Oxybate; Telemetry	2009
Pharmacological characteristics of zolpidem-induced catalepsy in the rat. Neuroscience letters, 2013, Nov-27, Volume: 556 Topics: Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Male; Naltrexone; Narcotic Antagonists; Pyridines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Time Factors; Zolpidem	2013
GluN2A-selective positive allosteric modulator-nalmefene-flumazenil reverses ketamine-fentanyl-dexmedetomidine-induced anesthesia and analgesia in rats. Scientific reports, 2020, 03-24, Volume: 10, Issue:1 Topics: Adjuvants, Anesthesia; Allosteric Regulation; Analgesia; Anesthesia; Animals; Delayed Emergence from Anesthesia; Dexmedetomidine; Drug Combinations; Drug Evaluation, Preclinical; Female; Fentanyl; Flumazenil; GABA-A Receptor Antagonists; Ketamine; Male; Maze Learning; Naltrexone; Narcotic Antagonists; Nociception; Pain Measurement; Rats; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Rotarod Performance Test	2020
Gypsies and drug addictions. Study of the adherence to treatment. European addiction research, 2000, Volume: 6, Issue:1 Topics: Adult; Cohort Studies; Cross-Cultural Comparison; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Naltrexone; Narcotic Antagonists; Patient Compliance; Retrospective Studies; Roma; Spain	2000