naltrexone and codeine

naltrexone has been researched along with codeine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199010 (27.03)18.7374
1990's7 (18.92)18.2507
2000's11 (29.73)29.6817
2010's9 (24.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheney, BV1
Bousquet, AR; Howes, JF; Kotick, MP; Leland, DL; Polazzi, JO1
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Andricopulo, AD; Moda, TL; Montanari, CA1
Aceto, MD; Coop, A; Harris, LS; May, EL; Metcalf, MD; Traynor, JR; Woods, JH1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Dalvie, D; Loi, CM; Smith, DA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brockmöller, J; Friesacher, HR; Meyer, MJ; Neumann, VE; Tzvetkov, MV; Zdrazil, B1
Gehrmann, JE; Killam, KF1
Carino, MA; Horita, A; Yamawaki, S1
Carino, MA; Chinn, C; Horita, A1
Mansour, A; Valenstein, ES1
Ferreira, SH; Follenfant, RL; Smith, TW1
Coale, EH; Hein, DW; Herling, S; Valentino, RJ; Woods, JH1
Herling, S2
Erenberg, G; Fogelson, MH; McConville, BJ; Norman, AB1
Eccles, R; Hutchings, HA1
Barasch, A; Cooper, SA; Hersh, EV; MacAfee, K; Ochs, H; Quinn, P1
Cutler, R; Fishbain, DA; Rosomoff, HL1
Manfredi, B; Mantegazza, P; Panerai, AE; Sacerdote, P1
Hirtl, C; Pfab, R; Zilker, T1
Hensel, M; Kox, WJ1
Cook, DB; O'Connor, PJ; Ray, CA1
Ott, J1
Luger, P; Messerschmidt, M; Morgenroth, W; Paulmann, C; Scheins, S1
Burton, DD; Busciglio, I; Camilleri, M; Manabe, N; McKinzie, S; Rao, AS; Ryks, M; Wong, BS; Zinsmeister, AR1
Farré-Albaladejo, M; Fernández-Nieva, Z; Gascón-Crespí, I; Hernández, RM; Igartua, M; Moreno-Vicente, R; Navarro, A; Pedraz, JL1
Donnerstag, N; Lüthi, A; Mehlig, A; Raetz Bravo, A; Schneider, T; Taegtmeyer, A1
Jiang, GH; Lv, XF; Ma, XF; Qiu, YW; Su, HH; Tian, JZ; Zhuo, FZ1
Abdossalami Asl, Y; Karami, M; Rezazadeh, M; Yamini, Y1

Reviews

4 review(s) available for naltrexone and codeine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Opiate detoxification protocols. A clinical manual.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1993, Volume: 5, Issue:1

    Topics: Administration, Cutaneous; Clinical Protocols; Clonidine; Codeine; Female; Humans; Male; Methadone; Naloxone; Naltrexone; Opioid-Related Disorders; Psychiatric Status Rating Scales; Receptors, Opioid; Substance Withdrawal Syndrome

1993

Trials

5 trial(s) available for naltrexone and codeine

ArticleYear
The opioid agonist codeine and antagonist naltrexone do not affect voluntary suppression of capsaicin induced cough in healthy subjects.
    The European respiratory journal, 1994, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Capsaicin; Codeine; Cough; Endorphins; Female; Humans; Male; Middle Aged; Naltrexone

1994
Narcotic receptor blockade and its effect on the analgesic response to placebo and ibuprofen after oral surgery.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 75, Issue:5

    Topics: Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Double-Blind Method; Drug Synergism; Endorphins; Female; Humans; Ibuprofen; Male; Naltrexone; Pain Measurement; Pain, Postoperative; Placebo Effect; Preanesthetic Medication; Receptors, Opioid; Time Factors; Tooth Extraction

1993
Opiate detoxification under anesthesia: no apparent benefit but suppression of thyroid hormones and risk of pulmonary and renal failure.
    Journal of toxicology. Clinical toxicology, 1999, Volume: 37, Issue:1

    Topics: Acute Kidney Injury; Adult; Anesthesia; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Respiratory Insufficiency; Substance Withdrawal Syndrome; Thyroid Hormones

1999
Muscle pain perception and sympathetic nerve activity to exercise during opioid modulation.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:5

    Topics: Adolescent; Adult; Blood Pressure; Codeine; Exercise; Hand Strength; Heart Rate; Humans; Male; Muscle, Skeletal; Naltrexone; Opioid Peptides; Pain; Pain Threshold; Perception; Placebos; Sympathetic Nervous System

2000
The effects of methylnaltrexone alone and in combination with acutely administered codeine on gastrointestinal and colonic transit in health.
    Alimentary pharmacology & therapeutics, 2010, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Combinations; Female; Gastrointestinal Tract; Gastrointestinal Transit; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Young Adult

2010

Other Studies

28 other study(ies) available for naltrexone and codeine

ArticleYear
Structure-activity relationships for drugs binding to the agonist and antagonist states of the primary morphine receptor.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Algorithms; Animals; Kinetics; Models, Molecular; Narcotic Antagonists; Narcotics; Protein Conformation; Rats; Receptors, Opioid; Structure-Activity Relationship

1988
Analgesic narcotic antagonists. 8. 7 alpha-Alkyl-4,5 alpha-epoxymorphinan-6-ones.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:12

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Codeine; Hydrocodone; In Vitro Techniques; Mice; Narcotic Antagonists; Rats; Reaction Time

1981
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
    NIDA research monograph, 1998, Volume: 178

    Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
The influence of esters and carboxylic acids as the N-substituent of opioids. Part 1: Benzomorphans.
    Bioorganic & medicinal chemistry, 2008, Jan-15, Volume: 16, Issue:2

    Topics: Analgesics, Opioid; Benzomorphans; Carboxylic Acids; Esters; Molecular Structure; Stereoisomerism; Structure-Activity Relationship

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
Opioids as Substrates and Inhibitors of the Genetically Highly Variable Organic Cation Transporter OCT1.
    Journal of medicinal chemistry, 2019, 11-14, Volume: 62, Issue:21

    Topics: Analgesics, Opioid; HEK293 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Organic Cation Transporter 1; Permeability; Protein Conformation

2019
Assessment of CNS drug activity in rhesus monkeys by analysis of the EEG.
    Federation proceedings, 1976, Volume: 35, Issue:11

    Topics: Amobarbital; Animals; Brain; Clorazepate Dipotassium; Codeine; Computers; Electroencephalography; Glutethimide; Haplorhini; Macaca mulatta; Morphine; Nalbuphine; Naloxone; Naltrexone

1976
Analeptic effect of opiate receptor agonists in rabbits.
    Neuroscience letters, 1985, Mar-22, Volume: 55, Issue:1

    Topics: Animals; Arousal; Brain; Central Nervous System Stimulants; Codeine; Cyclazocine; Dose-Response Relationship, Drug; Enkephalin, Methionine; Ethylketocyclazocine; Etorphine; Male; Meperidine; Methadone; Morphine; Naltrexone; Narcotics; Phenazocine; Rabbits; Receptors, Opioid; Reflex

1985
Codeine produces a cholinergically mediated analeptic effect in rats and rabbits.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1

    Topics: Animals; Brain; Central Nervous System Stimulants; Choline; Codeine; Diazepam; Drug Interactions; Male; Naltrexone; Pentobarbital; Rabbits; Rats; Rats, Inbred Strains; Synaptosomes

1988
Changes in responsiveness to mu and kappa opiates following a series of convulsions.
    Experimental neurology, 1985, Volume: 90, Issue:1

    Topics: Animals; Codeine; Dose-Response Relationship, Drug; Electroshock; Levorphanol; Mice; Mice, Inbred C57BL; Morphine; Naltrexone; Narcotics; Receptors, Opioid; Seizures

1985
Antinociceptive models displaying peripheral opioid activity.
    International journal of tissue reactions, 1985, Volume: 7, Issue:1

    Topics: Analgesics; Animals; Carrageenan; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Epoprostenol; Female; Indomethacin; Mice; Morphine; Movement; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists

1985
Narcotic discrimination in pigeons.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Clonidine; Codeine; Columbidae; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Ethylketocyclazocine; Ketamine; Meperidine; Morphine; Nalorphine; Naltrexone; Narcotics; Pentazocine; Pentobarbital; Species Specificity

1980
Effects of naltrexone dose and history of naltrexone exposure on food- and codeine-maintained responding in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:1

    Topics: Animals; Codeine; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Macaca mulatta; Naloxone; Naltrexone; Reaction Time

1981
Naltrexone effects on food-and codeine-maintained responding in rhesus monkeys.
    European journal of pharmacology, 1981, Jul-17, Volume: 73, Issue:1

    Topics: Animals; Behavior, Animal; Codeine; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Macaca mulatta; Naloxone; Naltrexone; Reinforcement, Psychology; Self Administration

1981
Sequential use of opioid antagonists and agonists in Tourette's syndrome.
    Lancet (London, England), 1994, Mar-05, Volume: 343, Issue:8897

    Topics: Adult; Codeine; Drug Administration Schedule; Female; Humans; Male; Naltrexone; Tourette Syndrome

1994
Antinociceptive and immunosuppressive effects of opiate drugs: a structure-related activity study.
    British journal of pharmacology, 1997, Volume: 121, Issue:4

    Topics: Animals; Cell Division; Codeine; Hydromorphone; Immune System; Immunosuppression Therapy; Interleukin-2; Male; Mice; Morphine; Nalorphine; Naloxone; Naltrexone; Narcotics; Oxycodone; Structure-Activity Relationship

1997
Safety, efficacy, and long-term results of a modified version of rapid opiate detoxification under general anaesthesia: a prospective study in methadone, heroin, codeine and morphine addicts.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:3

    Topics: Adult; Anesthesia, General; Codeine; Female; Heroin Dependence; Humans; Male; Methadone; Morphine Dependence; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Prospective Studies; Substance Withdrawal Syndrome

2000
Obviation of opioid withdrawal syndrome by concomitant administration of naltrexone in microgram doses: two psychonautic bioassays.
    Journal of psychoactive drugs, 2006, Volume: 38, Issue:1

    Topics: Codeine; Half-Life; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome

2006
Electron density analyses of opioids: a comparative study.
    The journal of physical chemistry. A, 2007, Jun-28, Volume: 111, Issue:25

    Topics: Analgesics, Opioid; Codeine; Cold Temperature; Dextromethorphan; Diprenorphine; Electrons; Models, Molecular; Morphine; Naltrexone; X-Ray Diffraction

2007
Development and validation of a bioanalytical method for the simultaneous determination of heroin, its main metabolites, naloxone and naltrexone by LC-MS/MS in human plasma samples: Application to a clinical trial of oral administration of a heroin/naloxo
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Administration, Oral; Calibration; Chromatography, Liquid; Codeine; Formates; Healthy Volunteers; Heroin; Humans; Hydrogen-Ion Concentration; Limit of Detection; Morphine; Naloxone; Naltrexone; Quality Control; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry

2015
Severe opioid withdrawal syndrome after a single dose of nalmefene.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:8

    Topics: Adult; Alcoholism; Analgesics, Opioid; Codeine; Contraindications; Drug Interactions; Humans; Male; Methadone; Middle Aged; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome

2015
Short-term UROD treatment on cerebral function in codeine-containing cough syrups dependent male individuals.
    European radiology, 2016, Volume: 26, Issue:9

    Topics: Adult; Anesthesia, General; Antitussive Agents; Brain; Brain Mapping; Codeine; Humans; Magnetic Resonance Imaging; Male; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Prospective Studies; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult

2016
On-chip pulsed electromembrane extraction as a new concept for analysis of biological fluids in a small device.
    Journal of chromatography. A, 2017, Dec-08, Volume: 1527

    Topics: Blood Chemical Analysis; Codeine; Electrochemistry; Electrodes; Humans; Limit of Detection; Liquid-Liquid Extraction; Membranes, Artificial; Naloxone; Naltrexone; Solvents; Urinalysis

2017