naltrexone and beta-naltrexamine

naltrexone has been researched along with beta-naltrexamine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Larson, DL; Portoghese, PS; Takemori, AE; Yim, CB1
Larson, DL; Lipkowski, AW; Portoghese, PS; Rice, KC; Ronsisvalle, G; Sayre, LM; Takemori, AE; Tam, SW; Yim, CB1
Botros, S; Lipkowski, AW; Portoghese, PS; Takemori, AE1
Larson, DL; Portoghese, PS; Ronsisvalle, G; Takemori, AE1
Erez, M; Portoghese, PS; Takemori, AE1
Broadbear, J; Derrick, I; Lewis, JW; Moynihan, HA; Woods, JH1
Archer, S; Bidlack, JM; Hutchinson, I; Lawrence, DM; Seyed-Mozaffari, A1
Aceto, MD; Bradbury, FA; Cami-Kobeci, G; Harris, LS; Husbands, SM; Lewis, JW; Neal, AP; Purington, LC; Traynor, JR1
Azar, MR; Cashman, JR; Ghirmai, S1
Akbarali, HI; Bilsky, EJ; Braithwaite, A; Dewey, WL; Scoggins, KL; Stevens, DL; Yuan, Y; Zhang, Y1
Dewey, WL; Gerk, PM; He, H; Kozak, P; Li, G; Mitra, P; Scoggins, KL; Selley, DE; Stevens, DL; Yuan, Y; Zhang, Y1
Arttamangkul, S; Birdsong, WT; Cheng, K; Clark, MJ; Rice, KC; Traynor, JR; Williams, JT1

Other Studies

12 other study(ies) available for naltrexone and beta-naltrexamine

ArticleYear
Long-acting agonist and antagonist activities of naltrexamine bivalent ligands in mice.
    European journal of pharmacology, 1990, Sep-21, Volume: 186, Issue:2-3

    Topics: Analgesics; Animals; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Receptors, Opioid, mu

1990
Stereostructure-activity relationship of opioid agonist and antagonist bivalent ligands. Evidence for bridging between vicinal opioid receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Animals; Brain; Chemical Phenomena; Chemistry; Endorphins; Guinea Pigs; Ileum; Naltrexone; Oxymorphone; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship

1985
Investigation of the structural requirements for the kappa-selective opioid receptor antagonist, 6 beta,6 beta'-[ethylenebis(oxyethyleneimino)]bis[17-(cyclopropylmethyl)- 4,5 alpha-epoxymorphinan-3,14-diol] (TENA).
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:5

    Topics: Animals; Electric Stimulation; Guinea Pigs; Ileum; Morphine; Naltrexone; Receptors, Opioid; Structure-Activity Relationship

1986
Synthesis and opioid antagonist potencies of naltrexamine bivalent ligands with conformationally restricted spacers.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Biological Assay; Chemical Phenomena; Chemistry; Cyclazocine; Endorphins; Ethylketocyclazocine; Guinea Pigs; Ileum; Molecular Conformation; Morphine; Muscle Contraction; Naltrexone; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship

1986
Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:7

    Topics: Animals; Chemical Phenomena; Chemistry; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Ligands; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists

1982
Potential irreversible ligands for opioid receptors. Cinnamoyl derivatives of beta-naltrexamine.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Mice; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid; Vas Deferens

1996
Fluorescent staining of kappa opioid receptors using naltrexamine derivatives and phycoerythrin.
    Journal of immunological methods, 1997, Feb-28, Volume: 201, Issue:2

    Topics: Animals; Biotin; Fluorescein; Fluoresceins; Fluorescent Dyes; Leukocytes; Mice; Naltrexone; Phycoerythrin; Receptors, Opioid, kappa; Spectrometry, Fluorescence; Tumor Cells, Cultured

1997
Mixed kappa/mu opioid receptor agonists: the 6 beta-naltrexamines.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Naltrexone; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spectrometry, Mass, Electrospray Ionization

2009
Synthesis and pharmacological evaluation of 6-naltrexamine analogs for alcohol cessation.
    Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18

    Topics: Alcohol Deterrents; Alcoholism; Animals; Humans; Liver; Male; Mice; Naltrexone; Nociceptin Receptor; Protein Binding; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship

2009
6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists.
    Bioorganic & medicinal chemistry letters, 2012, Jul-15, Volume: 22, Issue:14

    Topics: Animals; CHO Cells; Cricetinae; Mice; Molecular Structure; Naltrexone; Rats; Receptors, Opioid, mu

2012
Characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives as novel leads to development of mu opioid receptor selective antagonists.
    ACS chemical neuroscience, 2011, Jul-20, Volume: 2, Issue:7

    Topics: Animals; Caco-2 Cells; CHO Cells; Cricetinae; Cricetulus; Drug Implants; Guanosine 5'-O-(3-Thiotriphosphate); Heterocyclic Compounds; Humans; Male; Membranes; Mice; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Thalamus

2011
Increased agonist affinity at the μ-opioid receptor induced by prolonged agonist exposure.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Feb-27, Volume: 33, Issue:9

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Arrestin; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fibroblasts; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Ligands; Mice; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Opioid Peptides; Organic Chemicals; Pertussis Toxin; Pharmacological Phenomena; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Opioid, mu; Substrate Specificity; Time Factors; Transfection; Tritium

2013