naltrexone and aspartic acid

naltrexone has been researched along with aspartic acid in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faden, AI; Yum, SW1
Faden, AI; Graham, SH; Newman, A; Shimizu, H; Weinstein, P1
Chen, C; de Riel, JK; DesJarlais, RL; Li, JG; Liu-Chen, LY; Matecka, D; Rice, K; Yin, J; Zhang, Y1
Lisi, TL; Sluka, KA; Vance, CG1
Anton, RF; Couper, D; Goldman, D; O'Malley, S; Oroszi, G; Pettinati, H; Swift, R1
Ashenhurst, JR; Hutchison, KE; Morrow, AL; Ray, LA1
Berrettini, W; Gordon, AJ; Leong, SH; Lynch, KG; O'Brien, CP; Oslin, DW; Rukstalis, M1
Kayashima, S; Nagase, H; Oka, JI; Saitoh, A; Soda, A; Yamada, M; Yoshizawa, K1

Trials

3 trial(s) available for naltrexone and aspartic acid

ArticleYear
An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study.
    Archives of general psychiatry, 2008, Volume: 65, Issue:2

    Topics: Acamprosate; Adult; Alcoholism; Alleles; Amino Acid Substitution; Asparagine; Aspartic Acid; Cognitive Behavioral Therapy; Combined Modality Therapy; Drug Therapy, Combination; Female; Genetic Carrier Screening; Genetic Markers; Genotype; Homozygote; Humans; Liver Function Tests; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Pharmacogenetics; Polymorphism, Genetic; Prognosis; Receptors, Opioid, mu; Taurine; Temperance; Treatment Outcome

2008
Naltrexone selectively elevates GABAergic neuroactive steroid levels in heavy drinkers with the Asp40 allele of the OPRM1 gene: a pilot investigation.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:8

    Topics: Adult; Alcohol Drinking; Alcoholism; Alleles; Amino Acid Substitution; Aspartic Acid; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Male; Naltrexone; Pilot Projects; Polymorphism, Single Nucleotide; Pregnanolone; Receptors, Opioid, mu; Young Adult

2010
Naltrexone vs Placebo for the Treatment of Alcohol Dependence: A Randomized Clinical Trial.
    JAMA psychiatry, 2015, Volume: 72, Issue:5

    Topics: Adult; Alcohol Drinking; Alcoholism; Alleles; Asparagine; Aspartic Acid; Double-Blind Method; Drug Administration Schedule; Female; Genotype; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Odds Ratio; Polymorphism, Single Nucleotide; Recurrence; Treatment Outcome

2015

Other Studies

5 other study(ies) available for naltrexone and aspartic acid

ArticleYear
Comparison of the neuroprotective effects of the N-methyl-D-aspartate antagonist MK-801 and the opiate-receptor antagonist nalmefene in experimental spinal cord ischemia.
    Archives of neurology, 1990, Volume: 47, Issue:3

    Topics: Animals; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Humans; Ischemia; Male; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Rabbits; Spinal Cord; Time Factors

1990
Opioid receptor antagonist nalmefene stereospecifically inhibits glutamate release during global cerebral ischemia.
    Brain research, 1993, Dec-31, Volume: 632, Issue:1-2

    Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ischemic Attack, Transient; Kinetics; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reperfusion; Stereoisomerism; Taurine; Time Factors

1993
ASP147 in the third transmembrane helix of the rat mu opioid receptor forms ion-pairing with morphine and naltrexone.
    Life sciences, 1999, Volume: 65, Issue:2

    Topics: Animals; Aspartic Acid; Carboxylic Acids; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Ligands; Morphine; Mutagenesis, Site-Directed; Naltrexone; Protein Binding; Rats; Receptors, Opioid, mu

1999
High-frequency, but not low-frequency, transcutaneous electrical nerve stimulation reduces aspartate and glutamate release in the spinal cord dorsal horn.
    Journal of neurochemistry, 2005, Volume: 95, Issue:6

    Topics: Animals; Arthritis, Experimental; Aspartic Acid; Carrageenan; Chromatography, High Pressure Liquid; Glutamic Acid; Joints; Microdialysis; Naltrexone; Narcotic Antagonists; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Transcutaneous Electric Nerve Stimulation

2005
A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice.
    Journal of pharmacological sciences, 2018, Volume: 138, Issue:3

    Topics: Amino Acid Transport System X-AG; Animals; Anti-Anxiety Agents; Anxiety; Aspartic Acid; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Microinjections; Morphinans; Naltrexone; Prefrontal Cortex; Receptors, Opioid, delta

2018