naltrexone and acetaminophen

naltrexone has been researched along with acetaminophen in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's11 (50.00)29.6817
2010's10 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Murphy, DB; Murphy, MB; Prescott, LF; Sutton, JA1
Raffa, RB; Sterious, SN; Walker, EA1
Miranda, HF; Pinardi, G; Prieto, JC; Puig, MM1
Bakhle, YS; dos Reis, WG; França, DS; Francischi, JN; Menezes, GB; Rezende, RM1
Corley, G; Rawls, SM1
Hale, M; Katz, N; Morris, D; Stauffer, J1
Miranda, HF; Noriega, V; Prieto, JC1
Marjakangas, JM; Overheul, GJ; Thomassen, MC; van Cleef, KW; van Rij, RP1
Kokki, H; Kokki, M; Kuronen, M; Nyyssönen, T; Savolainen, S1
Bailey, CP; Cordery, SF; Delgado-Charro, MB; Guy, RH; Husbands, SM1

Reviews

3 review(s) available for naltrexone and acetaminophen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for naltrexone and acetaminophen

ArticleYear
Opioid-induced delay in gastric emptying: a peripheral mechanism in humans.
    Anesthesiology, 1997, Volume: 87, Issue:4

    Topics: Acetaminophen; Adult; Cross-Over Studies; Double-Blind Method; Female; Gastric Emptying; Humans; Male; Naltrexone; Narcotic Antagonists; Narcotics; Quaternary Ammonium Compounds

1997
Morphine sulfate and naltrexone hydrochloride extended release capsules in patients with chronic osteoarthritis pain.
    Postgraduate medicine, 2010, Volume: 122, Issue:4

    Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chronic Disease; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Naltrexone; Narcotic Antagonists; Osteoarthritis; Pain; Pain Measurement; Placebos; Treatment Outcome

2010
Life satisfaction and pain interference in spine surgery patients before and after surgery: comparison between on-opioid and opioid-naïve patients.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018, Volume: 27, Issue:11

    Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Drug Combinations; Elective Surgical Procedures; Female; Humans; Ketoprofen; Male; Meloxicam; Middle Aged; Naltrexone; Oxycodone; Pain; Pain Measurement; Personal Satisfaction; Prospective Studies; Quality of Life; Spine; Surveys and Questionnaires; Tromethamine; Young Adult

2018

Other Studies

16 other study(ies) available for naltrexone and acetaminophen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Opioid receptors and acetaminophen (paracetamol).
    European journal of pharmacology, 2004, Oct-25, Volume: 503, Issue:1-3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Dynorphins; Endorphins; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2004
Isobolographic analysis of multimodal analgesia in an animal model of visceral acute pain.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 88, Issue:4

    Topics: Acetaminophen; Acute Disease; Adrenergic alpha-Antagonists; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Ketoprofen; Male; Mice; Morphine; Muscarinic Antagonists; Naltrexone; Narcotic Antagonists; Pain; Prazosin

2008
Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain.
    British journal of pharmacology, 2008, Volume: 153, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carrageenan; Dipyrone; Disease Models, Animal; Hyperalgesia; Inflammation; Injections, Intralesional; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Rats, Wistar; Research Design; Time Factors

2008
Opioid, cannabinoid CB1 and NOP receptors do not mediate APAP-induced hypothermia in rats.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 92, Issue:3

    Topics: Acetaminophen; Aminoquinolines; Animals; Benzamides; Body Temperature; Hypothermia, Induced; Male; Naltrexone; Nociceptin Receptor; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Opioid; Rimonabant

2009
Previous administration of naltrexone did not change synergism between paracetamol and tramadol in mice.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 102, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Drug Synergism; Male; Mice; Naltrexone; Pain Measurement; Random Allocation; Tramadol

2012
Escape Mutations in NS4B Render Dengue Virus Insensitive to the Antiviral Activity of the Paracetamol Metabolite AM404.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4

    Topics: Acetaminophen; Antiviral Agents; Arachidonic Acids; Biotransformation; Dengue Virus; Drug Resistance, Multiple, Viral; Gene Expression; Genes, Reporter; HeLa Cells; Humans; Luciferases; Microbial Sensitivity Tests; Mutation; Naltrexone; Ribavirin; Viral Nonstructural Proteins; Virus Replication

2016
Simultaneous Transdermal Delivery of Buprenorphine Hydrochloride and Naltrexone Hydrochloride by Iontophoresis.
    Molecular pharmaceutics, 2019, 06-03, Volume: 16, Issue:6

    Topics: Acetaminophen; Buprenorphine; Drug Delivery Systems; Hydrogen-Ion Concentration; Iontophoresis; Naltrexone

2019