naltrexone has been researched along with 17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5'-guanidinyl-3,14-dihydroxyindolo(2',3'-6,7)morphinan in 5 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (40.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ferguson, DM; Metzger, TG; Paterlini, MG; Portoghese, PS | 1 |
Aschenbach, LC; He, H; Li, G; Selley, DE; Zhang, Y | 1 |
Burgman, M; Grinnell, S; Haselton, N; Majumdar, S; Ocampo, J; Pasternak, AR; Pasternak, GW | 1 |
Beletskaya, IO; Elbegdorj, O; Selley, DE; Yuan, Y; Zhang, Y | 1 |
Arnatt, CK; He, H; Kellogg, GE; Mosier, PD; Selley, DE; Zaidi, SA; Zhang, Y | 1 |
5 other study(ies) available for naltrexone and 17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5'-guanidinyl-3,14-dihydroxyindolo(2',3'-6,7)morphinan
Article | Year |
---|---|
Investigation of the selectivity of oxymorphone- and naltrexone-derived ligands via site-directed mutagenesis of opioid receptors: exploring the "address" recognition locus.
Topics: Amino Acid Sequence; Base Sequence; Binding, Competitive; Cell Line; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Naltrexone; Narcotic Antagonists; Oxymorphone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2001 |
14-O-Heterocyclic-substituted naltrexone derivatives as non-peptide mu opioid receptor selective antagonists: design, synthesis, and biological studies.
Topics: Binding, Competitive; Chemistry, Pharmaceutical; Drug Design; Humans; Kinetics; Ligands; Molecular Conformation; Molecular Structure; Naltrexone; Narcotic Antagonists; Nitrogen; Peptides; Protein Structure, Tertiary; Receptors, Opioid, mu | 2009 |
Generation of novel radiolabeled opiates through site-selective iodination.
Topics: Animals; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Iodine Radioisotopes; Molecular Structure; Neurotransmitter Agents; Oxymorphone; Radioligand Assay; Receptors, Opioid | 2011 |
Opioid receptor selectivity profile change via isosterism for 14-O-substituted naltrexone derivatives.
Topics: Molecular Conformation; Naltrexone; Narcotic Antagonists; Stereoisomerism; Structure-Activity Relationship | 2013 |
Binding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of mu opio
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Humans; Molecular Docking Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Naltrexone; Protein Binding; Protein Structure, Tertiary; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; Sequence Alignment | 2013 |