naloxonazine and naloxone

naloxonazine has been researched along with naloxone in 196 studies

Research

Studies (196)

TimeframeStudies, this research(%)All Research%
pre-199033 (16.84)18.7374
1990's71 (36.22)18.2507
2000's59 (30.10)29.6817
2010's31 (15.82)24.3611
2020's2 (1.02)2.80

Authors

AuthorsStudies
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L1
Briddon, SJ; Canals, M; Graham, B; Kellam, B; Scammells, PJ; Schembri, LS; Stoddart, LA1
Childers, SR; Nijssen, PC; Sexton, T1
Feuerstein, G; Paakkari, I; Paakkari, P; Sirén, AL2
Larson, AA; Mousseau, DD; Sun, X1
Cheng, PY; Cheng, Y; Decena, JA; Szeto, HH; Wu, DL1
Jang, Y; Yoburn, BC1
Baumann, MH; Rabii, J1
Pasternak, GW; Paul, D; Pick, CG1
Feuerstein, G; Paakkari, I; Paakkari, P1
Bridges, RS; Mann, PE; Pasternak, GW1
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW1
Liang, CS; Sakamoto, S1
Bodnar, RJ; Gistrak, MA; Pasternak, GW; Paul, D1
Heyman, JS; Jiang, Q; Mosberg, HI; Porreca, F; Rothman, RB1
Inturrisi, CE; Pasternak, GW; Paul, D; Standifer, KM1
Burks, TF; Heyman, JS; Mosberg, HI; Porreca, F; Williams, CL1
Pasternak, GW; Paul, D1
Pasternak, GW; Wood, PJ1
Arjune, D; Bodnar, RJ; Hahn, EF; Mann, PE; Pasternak, GW; Romero, MT1
Clark, JA; Houghten, R; Pasternak, GW1
Ling, GS; Lockhart, SH; Pasternak, GW; Spiegel, K1
Bodnar, RJ; Goldman, EJ; Pasternak, GW; Simone, DA1
Bodnar, RJ; Pasternak, GW; Portzline, T; Simone, DA1
Chang, JK; Huang, XH; Lu, WX; Mo, WY; Xu, SF; Xu, WM; Zhang, AZ; Zhou, KR1
Clark, JA; Ling, GS; Pasternak, GW; Simantov, R1
Itzhak, Y; Pasternak, GW1
Dray, A; Nunan, L; Wire, W1
Duffy, P; Kalivas, PW; Latimer, LG1
Cruciani, RA; Lutz, RA; Munson, PJ; Rodbard, D1
Bodnar, RJ; Curreri, G; Hahn, EF; Lubin, E; Mann, PE; Pasternak, GW1
Chang, JK; He, XP; Lu, WX; Niu, SF; Weber, E; Xu, SF; Xu, WM; Zhang, AZ; Zhou, KR1
Gmerek, DE; Woods, JH1
Itzhak, Y; Johnson, N; Pasternak, GW1
Houghten, RA; Johnson, N; Pasternak, GW1
Johnson, N; Pasternak, GW2
Dray, A; Nunan, L1
Rourke, JD; Shaw, JS1
Carroll-Buatti, M; Hahn, EF; Pasternak, GW1
Ling, GS; Nishimura, SL; Pasternak, GW; Spiegel, K1
Pasternak, GW; Wood, PL1
Gintzler, AR; Pasternak, GW1
Lee, S; Ling, GS; Lockhart, SH; MacLeod, JM; Pasternak, GW1
Garzón, J; Sánchez-Blázquez, P1
Kamei, J; Morita, K; Nagase, H; Saitoh, A2
Bodnar, RJ; Cole, JL; Kirkham, TC; Leventhal, L1
Bodnar, RJ; Bowen, WD; Cole, JL; Leventhal, L; Pasternak, GW1
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M; Saitoh, A; Suzuki, T1
Traynor, JR1
Bodnar, RJ; Glass, MJ; Koch, JE1
Kromer, W1
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T1
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M2
Elliott, J; Lambert, DG; Smart, D; Traynor, JR2
Bodnar, RJ; Glass, MJ; Hahn, B; Joseph, A1
Broccardo, M; Improta, G1
Búzás, B; Cox, BM; Izenwasser, S1
Kwok, YN; McIntosh, C; Yago, V1
Hitosugi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H1
Eisenberg, RM2
Imai, N; Kashiki, M; Liang, CS; Woolf, PD1
Randich, A; Robertson, JD; Willingham, T1
Callahan, P; Janik, J; Rabii, J1
Cheng, PY; Decena, J; McCabe, S; Soong, Y; Szeto, HH; Wu, D1
Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T1
Bodnar, RJ; Koch, JE1
Nejat, RJ; Pasternak, GW; Pick, CG1
Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Nagase, H; Suzuki, T1
Henriksen, SJ; Koob, GF; Mattox, A; Negus, SS; Pasternak, GW; Portoghese, PS; Takemori, AE; Weinger, MB1
Plotsky, PM; Rivest, S; Rivier, C1
Feuerstein, G; Paakkari, I; Paakkari, P; Sirén, AL; Vonhof, S1
Cheng, PY; Decena, JA; McCabe, S; Soong, Y; Szeto, HH; Wu, D1
Beczkowska, IW; Bodnar, RJ; Bostock, ME; Koch, JE; Leibowitz, SF1
Koob, GF; Negus, SS; Pasternak, GW; Weinger, MB1
Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M1
Negri, L; Noviello, L; Noviello, V1
Honkanen, A; Hyytiä, P; Korpi, ER; Sarviharju, M; Vilamo, L; Wegelius, K1
Bergman, J; Gatch, MB; Liguori, A; Liguori, T; Mello, NK; Negus, SS1
Bodnar, RJ; Cole, JL; Leventhal, L1
Ahtee, L; Piepponen, TP1
Beatty, MF; Chen, SW; Davies, MF; Loew, GH; Maguire, PA1
Bodnar, RJ; Leventhal, L1
Kamei, J; Nagase, H; Sodeyama, M; Suzuki, T; Tsuda, M1
Di Chiara, G; Pontieri, FE; Tanda, G1
Ahtee, L; Katajamäki, J; Kivastik, T; Piepponen, TP; Zharkovsky, A1
Bontempi, B; Sharp, FR1
Lysle, DT; Perez, L1
Aasmundstad, TA; Alkana, RL; Grung, M; Handal, M; Mørland, J; Skurtveit, S1
Aimi, N; Matsumoto, K; Sakai, S; Takayama, H; Thongpradichote, S; Tohda, M; Watanabe, H1
Lattanzi, R; Melchiorri, P; Negri, L; Tabacco, F1
Di Chiara, G; Tanda, G1
Franck, J; Lindholm, S; Raaschou, P1
Fujimoto, JM; Gorny, JM; Rady, JJ1
Arcaya, JL; Cano, G; Gómez, G; Maixner, W; Suárez-Roca, H1
Kisara, K; Sakurada, S; Sakurada, T; Sato, T; Takahashi, N; Tan-No, K; Wako, K1
Chen, YC; Cheng, JT; Chi, TC; Liu, IM; Lu, FH1
Fujimura, T; Kastin, AJ; Katsuyama, S; Murayama, K; Sakurada, S; Sakurada, T; Ueda, H; Yuki, M; Zadina, JE1
Aimi, N; Horie, S; Pang, PK; Ponglux, D; Sakai, S; Shan, J; Takayama, H; Watanabe, K; Yamamoto, LT; Yano, S1
Meert, TF; Verborgh, C1
Fujii, T; Goto, T; Motoyama, Y; Ochi, T1
Kamei, J; Nagase, H; Ohsawa, M; Zushida, K1
Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, S; Tadano, T; Takahashi, N; Tan-No, K; Yonezawa, A1
Hayashi, T; Kisara, K; Kutsuwa, M; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeda, S; Tan-No, K; Yuki, M1
Baumer, F; Bodnar, RJ; Pasternak, GW; Rossi, GC; Stein, JA; Znamensky, V1
Arakawa, K; Saito, N; Sasaki, T; Shimada, K1
Hirohashi, M; Kitano, Y; Komiyama, C; Makino, M; Takasuna, K1
Akil, H; Bonner, G; Meng, F1
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE1
Barone, FC; Feuerstein, GZ; Millison, JH; Paakkari, P; Price, WJ; Sirén, AK; Vonhof, S1
Pasternak, GW1
Colman, AS; Miller, JH3
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE1
Chang, CJ; Cheng, JT; Chi, TC; Liu, IM; Lu, FH; Tzeng, TF1
Katoh, T; Mamiya, T; Ukai, M1
Lin, HP; Ukai, M1
Browning, KN; Kalyuzhny, AE; Travagli, RA1
Chang, SL; Cheng, JT; Lin, JG1
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE1
Imai, S; Itou, Y; Narita, M; Suzuki, T; Yajima, Y1
Ciccocioppo, R; Martin-Fardon, R; Weiss, F1
Rademacher, DJ; Steinpreis, RE1
Cheng, JT; Lai, TY; Liu, IM; Tsai, CC; Tzeng, TF1
Bardo, MT; Gehrke, BJ; Rauhut, AS; Shortridge, BE1
Qian, X; Soong, Y; Szeto, HH; Wu, D; Zhao, GM1
Holloway, F; Mhatre, M1
Calvo, F; Carvalho, AD; Castellan-Baldan, L; Coimbra, NC; da Silva, LA; de Oliveira, R; Elias-Filho, DH; Felippotti, TT; Motta, V; Osaki, MY; Paschoalin-Maurin, T; Ubiali, WA1
Laurito, CE; Lu, Y; Sweitzer, SM; Yeomans, DC1
Hayashi, T; Mizoguchi, H; Sakurada, C; Sakurada, S; Sakurada, T; Watanabe, H; Yonezawa, A; Yuhki, M1
Chen, CM; Huang, EY; Tao, PL1
Chitravanshi, VC; Kasamatsu, K; Sapru, HN1
Gutkowska, J; Jankowski, M; Mukaddam-Daher, S; Schiller, PW1
Fujimura, T; Ito, K; Kawamura, S; Mizoguchi, H; Murayama, K; Nakayama, D; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H1
Ambo, A; Bryant, SD; Fujita, Y; Jinsmaa, Y; Lazarus, LH; Li, T; Miyazaki, A; Okada, Y; Sasaki, Y; Shiotani, K; Tsuda, Y1
Kasamatsu, K; Sapru, HN1
Coimbra, NC; Freitas, RL; Kishi, R; Morato, S; Rebouças, EC; Savoldi, M; Segato, EN1
Ahern, DG; Egan, JA; Filer, CN; Seguin, RJ1
Carvalho, AD; Castellan-Baldan, L; Ciscato, JG; Coimbra, NC; Corrêa, SA; D'Angelo-Dias, R; de Oliveira, R; de Oliveira, RC; Felippotti, TT; Hoffmann, A; Moreira, JE; Rebouças, EC; Ribeiro, SJ1
Aragon, CM; Pastor, R1
Koseki, M; Matsumura, E; Sakaguchi, M; Wakamatsu, M1
Chang, CJ; Cheng, JT; Huang, CC; Liu, IM; Tzeng, TF1
Cagniard, B; Cazala, P; Le Merrer, J1
Bagosi, Z; Bujdosó, E; Jászberényi, M; Szabó, G; Telegdy, G1
Fushiki, T; Inoue, K; Matsumura, S; Mizushige, T; Tsuzuki, S; Yoneda, T1
Kamei, J; Nozaki, C1
Banoub, J; Cohen, AM; El Essassi, M; Joly, N; Martin, P; Massoui, M; Vaillant, C1
Bergeson, SE; Gonzales, RA; Hall, FS; Job, MO; Sora, I; Tang, A; Uhl, GR1
Mizoguchi, H; Nakayama, D; Sakurada, S; Sakurada, T; Watanabe, C; Watanabe, H1
Chen, Q; Dong, L; Fu, CY; Ni, JM; Wang, R; Zhao, YL1
Andoh, T; Konno, M; Kuraishi, Y; Nemoto, H; Nojima, H; Takahata, H; Yageta, Y; Yamaguchi-Miyamoto, T1
Komatsu, T; Mizoguchi, H; Morimoto, M; Sakurada, S; Sakurada, T; Sato, T; Sawai, T; Watanabe, C; Watanabe, H; Yonezawa, A1
Aloyo, VJ; Chaijale, NN; Simansky, KJ1
Bagosi, Z; Jászberényi, M; Telegdy, G1
Achat-Mendes, C; Platt, DM; Rowlett, JK; Spealman, RD; Valdez, GR1
Fichna, J; Gach, K; Janecka, A; Piestrzeniewicz, M; Szemraj, J1
Morato, GS; Varaschin, RK1
Cheng, JT; Liu, IM; Wu, HT; Yang, TT1
Cooper, PD; Cowlings, A; Dennis, SR; Donnelly, C; Woodman, JD1
Górski, K; Misztal, T; Romanowicz, K; Tomaszewska-Zaremba, D1
Baiula, M; Bedini, A; De Marco, R; Gentilucci, L; Spampinato, S; Tolomelli, A1
Chen, IH; Cheng, JT; Tong, YC; Yu, BC1
Bicalho, Ude O; Coimbra, NC; do Carmo, DR; Felippotti, TT; Fraceto, LF; Grillo, R; Paim, LL; Parada, CA; Stradiotto, NR1
Chen, ZC; Cheng, JT; Chung, HH; Hung, CH; Lin, HJ; Shieh, JP1
Acquas, E; Fois, GR; Muggironi, G; Peana, AT; Vinci, S; Zinellu, M1
Ang, KK; Arkin, MR; Chen, S; De Muylder, G; Engel, JC; McKerrow, JH1
Bertini, S; Menozzi, A; Poli, E; Pozzoli, C; Serventi, P; Zullian, C1
Coimbra, NC; de Freitas, RL; Felippotti, TT1
Goyal, R; Kumar, K; Mohan, A; Mudgal, A; Pasha, S1
Dobek, E; Górski, K; Misztal, T; Molik, E; Romanowicz, K1
Chen, W; Cheng, JT; Chung, HH1
Chien, CC; Fan, LW; Ho, IK; Lee, YJ; Tien, LT1
Prado, WA; Reis, GM; Rossaneis, AC; Silveira, JW1
Arulselvan, P; Fakurazi, S; Hairuszah, I; Hidayat, MT; Moklas, MAM; Shamima, AR1
Bach-Rojecky, L; Drinovac, V; Lacković, Z; Matak, I1
Aoki, S; Inoue, K; Itoh, T; Komiya, S; Mori, T; Shibasaki, M; Suzuki, T; Uzawa, N1
Dobek, E; Górski, K; Misztal, T; Romanowicz, K1
Kon-No, T; Mizoguchi, H; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H; Yonezawa, A1
Adachi, S; Fushiki, T; Inoue, K; Matsumura, S; Okafuji, Y; Okahashi, T; Sakamoto, K; Tsuzuki, S1
Aranda-Fernández, PE; Chotro, MG; Gaztañaga, M1
Drdla-Schutting, R; Forsthuber, L; Gerhold, KJ; Honsek, SD; Sandkühler, J1
Bach-Rojecky, L; Drinovac Vlah, V; Lacković, Z1
Can, ÖD; Kasap, M1
Denton, DA; Lawrence, AJ; Leeboonngam, T; McKinley, MJ; Smith, CM; Walker, LL1
Caljon, G; De Muylder, G; Dujardin, JC; McKerrow, J; Vanhollebeke, B; Wolfe, AR1
da Luz, SC; Nogueira, CW; Pesarico, AP; Rosa, SG; Tagliapietra, CF1
Almada, RC; Bazaglia-de-Sousa, G; Calvo, F; Coimbra, NC; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Lobão-Soares, B; Medeiros, P; Paschoalin-Maurin, T; Silva, JAD1
Almada, RC; Calvo, F; Coimbra, NC; da Silva Soares, R; da Silva, JA; de Paiva, YB; Medeiros, P; Roncon, CM1
Liu, X; Ma, M; Wang, K; Wang, R; Wang, Y; Wei, S; Zhang, X; Zhao, L; Zhou, J1
Coimbra, NC; de Araújo Berber, RC; de Avila, DR; de Oliveira, RC; Maia Fernandes, BF; Oliveira, R; Pichinelli Maffei, TH; Santana, VC; Streg, RV; Vale, JS1

Reviews

3 review(s) available for naloxonazine and naloxone

ArticleYear
Multiple mu opiate receptors.
    Life sciences, 1986, May-26, Volume: 38, Issue:21

    Topics: Aging; Analgesia; Animals; Autoradiography; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylmaleimide; Morphine; Naloxone; Neurotransmitter Agents; Phylogeny; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Substance-Related Disorders; Tissue Distribution

1986
Opioid receptors and their subtypes: focus on peripheral isolated tissue preparations.
    Neurochemistry international, 1994, Volume: 24, Issue:5

    Topics: Animals; GTP-Binding Proteins; Guinea Pigs; Humans; Mice; Naloxone; Narcotic Antagonists; Narcotics; Organ Specificity; Peripheral Nerves; Receptors, Opioid; Signal Transduction

1994
Insights into mu opioid pharmacology the role of mu opioid receptor subtypes.
    Life sciences, 2001, Apr-06, Volume: 68, Issue:19-20

    Topics: Alternative Splicing; Analgesia; Animals; Cloning, Molecular; Down-Regulation; Humans; Morphine; Morphine Derivatives; Naloxone; Narcotics; Receptors, Opioid, mu; RNA, Messenger; Trans-Activators

2001

Other Studies

193 other study(ies) available for naloxonazine and naloxone

ArticleYear
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software

1994
Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor.
    Journal of medicinal chemistry, 2015, Dec-24, Volume: 58, Issue:24

    Topics: Animals; Binding, Competitive; Buprenorphine; CHO Cells; Cricetulus; Fluorescent Dyes; HEK293 Cells; Humans; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Radioligand Assay; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship

2015
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
    Journal of neurochemistry, 1992, Volume: 59, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride

1992
Evidence for differential opioid mu 1- and mu 2-receptor-mediated regulation of heart rate in the conscious rat.
    Neuropharmacology, 1992, Volume: 31, Issue:8

    Topics: Analgesics, Opioid; Animals; Blood Pressure; Heart Rate; Injections, Intraventricular; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1992
Identification of a novel receptor mediating substance P-induced behavior in the mouse.
    European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Binding Sites; Indoles; Injections, Spinal; Male; Mice; Morphinans; Naloxone; Naltrexone; Peptide Fragments; Substance P

1992
The effects of selective mu1 opiate receptor blockade on breathing patterns in the fetal lamb.
    Pediatric research, 1991, Volume: 30, Issue:2

    Topics: Animals; Electromyography; Fetus; Gestational Age; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Sheep

1991
Evaluation of receptor mechanism mediating fentanyl analgesia and toxicity.
    European journal of pharmacology, 1991, May-17, Volume: 197, Issue:2-3

    Topics: Analgesics; Animals; Brain; Drug Tolerance; Fentanyl; Lethal Dose 50; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid

1991
Inhibition of suckling-induced prolactin release by mu- and kappa-opioid antagonists.
    Brain research, 1991, Dec-20, Volume: 567, Issue:2

    Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Lactation; Luteinizing Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid, kappa; Receptors, Opioid, mu

1991
Comparison of naloxonazine and beta-funaltrexamine antagonism of mu 1 and mu 2 opioid actions.
    Life sciences, 1991, Volume: 48, Issue:21

    Topics: Animals; Drug Administration Schedule; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Subcutaneous; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu

1991
Respiratory and locomotor stimulation by low doses of dermorphin, a mu1 receptor-mediated effect.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: Analgesics, Opioid; Animals; Flumazenil; Male; Motor Activity; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration

1990
Dermorphin tetrapeptide analog induces naloxonazine-reversible respiratory stimulation.
    Progress in clinical and biological research, 1990, Volume: 328

    Topics: Analgesics; Animals; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Tidal Volume

1990
Mu 1 opioid receptor involvement in maternal behavior.
    Physiology & behavior, 1990, Volume: 47, Issue:1

    Topics: Animals; Behavior, Animal; Female; Maternal Behavior; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1990
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship

1985
Opiate receptor inhibition improves the blunted baroreflex function in conscious dogs with right-sided congestive heart failure.
    Circulation, 1989, Volume: 80, Issue:4

    Topics: Animals; Blood Pressure; Consciousness; Dogs; Electrocardiography; Enkephalin, Leucine; Heart Failure; Naloxone; Narcotic Antagonists; Oxymorphone; Phenylephrine; Pressoreceptors; Receptors, Opioid; Reflex

1989
Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice.
    European journal of pharmacology, 1989, Sep-22, Volume: 168, Issue:3

    Topics: Analgesia; Anesthesia, Spinal; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1989
Modulation of mu-mediated antinociception by delta agonists: characterization with antagonists.
    European journal of pharmacology, 1989, Oct-04, Volume: 169, Issue:1

    Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1989
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2

    Topics: Analgesia; Animals; Drug Tolerance; Gastrointestinal Motility; Male; Mice; Morphine; Morphine Derivatives; Naloxone

1989
Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Motility; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1988
Differential blockade by naloxonazine of two mu opiate actions: analgesia and inhibition of gastrointestinal transit.
    European journal of pharmacology, 1988, May-10, Volume: 149, Issue:3

    Topics: Analgesics; Animals; Gastrointestinal Transit; Male; Mice; Morphine; Naloxone; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu

1988
Differential sensitivity of opioid-induced feeding to naloxone and naloxonazine.
    Psychopharmacology, 1988, Volume: 94, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Eating; Electroshock; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains

1988
Opiate binding in calf thalamic membranes: a selective mu 1 binding assay.
    Molecular pharmacology, 1988, Volume: 34, Issue:3

    Topics: Animals; Cattle; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus

1988
Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Analgesia; Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration

1985
Involvement of opioid receptor subtypes in rat feeding behavior.
    Life sciences, 1985, Mar-04, Volume: 36, Issue:9

    Topics: Animals; Deoxyglucose; Feeding Behavior; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1985
Antagonism of morphine analgesia by intracerebroventricular naloxonazine.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6

    Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1986
[Analgesic effect of metorphamide on skin pain and visceral pain].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:1

    Topics: Analgesics; Animals; Enkephalin, Methionine; Female; Male; Mice; Morphine; Naloxone; Pain; Rabbits; Receptors, Opioid; Receptors, Opioid, mu; Sensory Thresholds

1986
Naloxonazine actions in vivo.
    European journal of pharmacology, 1986, Sep-23, Volume: 129, Issue:1-2

    Topics: Animals; Brain; Kinetics; Male; Mice; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid

1986
Interaction of [D-Ser2,Leu5]enkephalin-Thr6 (DSLET), a relatively selective delta ligand, with mu1 opioid binding sites.
    Life sciences, 1987, Jan-19, Volume: 40, Issue:3

    Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Male; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid

1987
Naloxonazine and opioid-induced inhibition of reflex urinary bladder contractions.
    Neuropharmacology, 1987, Volume: 26, Issue:1

    Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Male; Muscle Contraction; Naloxone; Rats; Receptors, Opioid; Reflex; Urinary Bladder

1987
Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Male; Motor Activity; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tegmentum Mesencephali

1987
Naloxonazine effects on the interaction of enkephalin analogs with mu-1, mu and delta opioid binding sites in rat brain membranes.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1987
Comparison of effects of chronic administration of naloxone and naloxonazine upon food intake and maintainance of body weight in rats.
    Neuropharmacology, 1988, Volume: 27, Issue:4

    Topics: Aging; Animals; Appetite Depressants; Body Weight; Feeding Behavior; Male; Naloxone; Rats; Rats, Inbred Strains

1988
The analgesic and respiratory depressant actions of metorphamide in mice and rabbits.
    Neuropeptides, 1985, Volume: 6, Issue:2

    Topics: Analgesics; Animals; Depression, Chemical; Enkephalin, Methionine; Female; Injections, Intraventricular; Male; Mice; Naloxone; Rabbits; Respiration; Sensory Thresholds

1985
Effects of beta-funaltrexamine in normal and morphine-dependent rhesus monkeys: observational studies.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Macaca mulatta; Morphine; Muscle Relaxation; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1985
Interaction of two phencyclidine opiate-like derivatives with 3H-opioid binding sites.
    European journal of pharmacology, 1984, Jun-01, Volume: 101, Issue:3-4

    Topics: Analgesics; Animals; Binding, Competitive; Dihydromorphine; Male; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu

1984
[3H]-beta-endorphin binding in rat brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1984, Volume: 4, Issue:10

    Topics: Animals; beta-Endorphin; Binding Sites; Binding, Competitive; Brain; Endorphins; Male; Naloxone; Rats; Rats, Inbred Strains; Tritium

1984
Binding of [3H]naloxonazine to rat brain membranes.
    Molecular pharmacology, 1984, Volume: 26, Issue:3

    Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Naloxone; Rats; Receptors, Opioid; Thermodynamics; Tissue Distribution

1984
Evidence that naloxonazine produces prolonged antagonism of central delta opioid receptor activity in vivo.
    Brain research, 1984, Dec-03, Volume: 323, Issue:1

    Topics: Animals; Central Nervous System; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Urinary Bladder

1984
Failure to demonstrate mu-isoreceptors.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Animals; Benzomorphans; Female; Mice; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, mu; Respiration

1984
Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1982, Volume: 2, Issue:5

    Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Drug Stability; Hydromorphone; Kinetics; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship

1982
Dissociation of morphine's analgesic and respiratory depressant actions.
    European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4

    Topics: Analgesia; Animals; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration

1983
The binding to rat brain homogenates of Mr2034, a universal opiate.
    Life sciences, 1983, Sep-05, Volume: 33, Issue:10

    Topics: Animals; Benzomorphans; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Male; Morphinans; Naloxone; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid

1983
Specific mu 2 opioid isoreceptor regulation of nigrostriatal neurons: in vivo evidence with naloxonazine.
    Neuroscience letters, 1983, Jun-30, Volume: 37, Issue:3

    Topics: Animals; Corpus Striatum; Dopamine; Male; Morphine; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu; Substantia Nigra

1983
Multiple mu receptors: evidence for mu2 sites in the guinea pig ileum.
    Neuroscience letters, 1983, Aug-19, Volume: 39, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Dihydromorphine; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Naloxone; Oxymorphone; Receptors, Opioid; Receptors, Opioid, mu

1983
Separation of morphine analgesia from physical dependence.
    Science (New York, N.Y.), 1984, Oct-26, Volume: 226, Issue:4673

    Topics: Analgesia; Animals; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders

1984
In vivo injection of antibodies directed against the cloned mu opioid receptor blocked supraspinal analgesia induced by mu-agonists in mice.
    Life sciences, 1995, Volume: 56, Issue:14

    Topics: Amino Acid Sequence; Analgesia; Animals; Antibodies; Benzeneacetamides; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immunization, Passive; Male; Mice; Molecular Sequence Data; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1995
Antagonistic effect of buprenorphine on the antitussive effect of morphine is mediated via the activation of mu 1-opioid receptors.
    Life sciences, 1995, Volume: 57, Issue:16

    Topics: Animals; Antitussive Agents; Buprenorphine; Capsaicin; Cough; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Opioid, mu; Time Factors

1995
Selective actions of central mu and kappa opioid antagonists upon sucrose intake in sham-fed rats.
    Brain research, 1995, Jul-10, Volume: 685, Issue:1-2

    Topics: Animals; Cerebral Ventricles; Eating; Enkephalin, Leucine-2-Alanine; Infusions, Parenteral; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sucrose

1995
Reductions in body weight following chronic central opioid receptor subtype antagonists during development of dietary obesity in rats.
    Brain research, 1995, Apr-24, Volume: 678, Issue:1-2

    Topics: Animals; Body Weight; Dietary Fats; Eating; Male; Naloxone; Naltrexone; Narcotic Antagonists; Obesity; Rats; Rats, Sprague-Dawley; Time Factors

1995
Modification of mu-opioid agonist-induced locomotor activity and development of morphine dependence by diabetes.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid, mu; Streptozocin

1995
Analysis of central opioid receptor subtype antagonism of hypotonic and hypertonic saline intake in water-deprived rats.
    Brain research bulletin, 1995, Volume: 36, Issue:3

    Topics: Animals; Enkephalin, Leucine-2-Alanine; Hypotonic Solutions; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saline Solution, Hypertonic; Water Deprivation

1995
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline

1995
Antinociceptive effect of dihydroetorphine in diabetic mice.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Binding, Competitive; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu

1995
Effect of diabetes on the morphine-induced inhibition of gastrointestinal transit.
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1995, Volume: 15, Issue:2

    Topics: Animals; Depression, Chemical; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gastrointestinal Transit; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone

1995
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
    European journal of pharmacology, 1994, Aug-16, Volume: 268, Issue:3

    Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured

1994
Effects of diabetes on the morphine-induced Straub tail reaction in mice.
    Neuroscience letters, 1994, Aug-29, Volume: 178, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Reference Values; Tail

1994
Central opioid receptor subtype mediation of isoproterenol-induced drinking in rats.
    Brain research, 1994, 09-19, Volume: 657, Issue:1-2

    Topics: Animals; Drinking; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu

1994
Effect of selective mu 1, mu 2 and delta 2 opioid receptor agonists on gastric functions in the rat.
    Neuropharmacology, 1994, Volume: 33, Issue:8

    Topics: Animals; Dose-Response Relationship, Drug; Gastric Acid; Gastric Emptying; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach

1994
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin

1993
Beta-funaltrexamine blockade of opioid-induced inhibition of somatostatin secretion from rat stomach.
    European journal of pharmacology, 1994, Jul-11, Volume: 259, Issue:3

    Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gastric Inhibitory Polypeptide; Gastric Mucosa; In Vitro Techniques; Male; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin

1994
Streptozotocin-induced diabetes selectively reduces antinociception mediated by mu 1-opioid receptors, but not that mediated by mu 2-opioid receptors.
    Neuroscience letters, 1994, Jan-03, Volume: 165, Issue:1-2

    Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid, mu; Spinal Cord

1994
TRIMU-5, a mu 2-opioid receptor agonist, stimulates the hypothalamo-pituitary-adrenal axis.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Kinetics; Male; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1994
Comparison of cardiovascular effects of mu- and delta-opioid receptor antagonists in dogs with congestive heart failure.
    The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2

    Topics: Animals; Blood Circulation; Cardiovascular System; Dogs; Enkephalin, Leucine; Heart Failure; Hemodynamics; Naloxone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, mu; Regional Blood Flow; Ventricular Function, Right

1994
The use of specific opioid agonists and antagonists to delineate the vagally mediated antinociceptive and cardiovascular effects of intravenous morphine.
    Brain research, 1993, Feb-19, Volume: 603, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analysis of Variance; Animals; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heart Rate; Hexamethonium; Hexamethonium Compounds; Indoles; Injections, Intravenous; Male; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors; Vagotomy; Vagus Nerve

1993
Characterization of the mu-opioid receptors on SH-SY5Y cells using beta-funaltrexamine (beta-FNA) and naloxonazine.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Analgesics; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid, mu; Tumor Cells, Cultured

1993
Morphine induced analgesia is attenuated in post-partum lactating rats.
    Life sciences, 1993, Volume: 52, Issue:3

    Topics: Analgesia; Animals; Diestrus; Female; Injections, Intravenous; Lactation; Male; Morphine; Naloxone; Postpartum Period; Rats; Rats, Sprague-Dawley; Receptors, Opioid

1993
Opioid-induced stimulation of fetal respiratory activity by [D-Ala2]deltorphin I.
    European journal of pharmacology, 1993, Jan-05, Volume: 230, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Electromyography; Female; Fetus; Indoles; Injections, Intraventricular; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pregnancy; Receptors, Opioid, delta; Respiration; Sheep

1993
Morphine-induced place preference in the CXBK mouse: characteristics of mu opioid receptor subtypes.
    Brain research, 1993, Jan-29, Volume: 602, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Appetitive Behavior; Benzazepines; Choice Behavior; Conditioning, Classical; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Morphine; Motivation; Naloxone; Pyrrolidines; Receptors, Dopamine D1; Receptors, Opioid, mu; Sodium Chloride

1993
Involvement of mu1 and mu2 opioid receptor subtypes in tail-pinch feeding in rats.
    Physiology & behavior, 1993, Volume: 53, Issue:3

    Topics: Animals; Arousal; Enkephalin, Leucine-2-Alanine; Feeding Behavior; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1993
Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1

    Topics: Analgesia; Animals; Brain Stem; Drug Administration Routes; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid, mu; Species Specificity; Spinal Cord

1993
Possible involvement of mu 2-mediated mechanisms in mu-mediated antitussive activity in the mouse.
    Neuroscience letters, 1993, Jan-12, Volume: 149, Issue:2

    Topics: Analgesics; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Reaction Time; Receptors, Opioid, mu

1993
Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

    Topics: Animals; Heroin; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration

1993
CRF alters the infundibular LHRH secretory system from the medial preoptic area of female rats: possible involvement of opioid receptors.
    Neuroendocrinology, 1993, Volume: 57, Issue:2

    Topics: Animals; Corticotropin-Releasing Hormone; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Luteinizing Hormone; Naloxone; Naltrexone; Ovariectomy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu

1993
Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors?
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Amino Acid Sequence; Analgesics; Animals; Catalepsy; Dose-Response Relationship, Drug; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Respiration

1993
DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Analgesics; Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Male; Naloxone; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1993
Role of mu 1- and delta-opioid receptors in modulation of fetal EEG and respiratory activity.
    The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 2

    Topics: Animals; Electroencephalography; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fetal Movement; Fetus; Morphine; Naloxone; Naltrexone; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Sheep

1993
Central opioid receptor subtype antagonists differentially reduce intake of saccharin and maltose dextrin solutions in rats.
    Brain research, 1993, Aug-06, Volume: 618, Issue:2

    Topics: Animals; Drinking Behavior; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Saccharin

1993
Antagonist effects of beta-funaltrexamine and naloxonazine on alfentanil-induced antinociception and muscle rigidity in the rat.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Alfentanil; Analgesia; Animals; Electromyography; Male; Muscle Rigidity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar

1993
Discriminative stimulus properties of morphine mediated by mu 1-opioid receptors.
    European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred F344; Receptors, Opioid, mu

1995
Antinociceptive and behavioral effects of synthetic deltorphin analogs.
    European journal of pharmacology, 1996, Jan-18, Volume: 296, Issue:1

    Topics: Analysis of Variance; Animals; Catalepsy; Dose-Response Relationship, Drug; Injections, Intraventricular; Locomotion; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu

1996
Alcohol drinking is reduced by a mu 1- but not by a delta-opioid receptor antagonist in alcohol-preferring rats.
    European journal of pharmacology, 1996, May-23, Volume: 304, Issue:1-3

    Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking; Eating; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraperitoneal; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Receptors, Opioid, mu

1996
Naloxonazine antagonism of levorphanol-induced antinociception and respiratory depression in rhesus monkeys.
    European journal of pharmacology, 1996, Feb-29, Volume: 298, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Levorphanol; Macaca mulatta; Naloxone; Narcotic Antagonists; Respiration; Respiratory Insufficiency

1996
Reductions in locomotor activity following central opioid receptor subtype antagonists in rats.
    Physiology & behavior, 1996, Volume: 60, Issue:3

    Topics: Animals; Enkephalins; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley

1996
Effects of selective opioid receptor antagonists on morphine-induced changes in striatal and limbic dopamine metabolism.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu

1995
Evidence for mu1-opioid receptor involvement in fentanyl-mediated respiratory depression.
    European journal of pharmacology, 1996, Sep-26, Volume: 312, Issue:2

    Topics: Animals; Carbon Dioxide; Fentanyl; Naloxone; Oxygen; Rats; Receptors, Opioid, mu; Respiration; Respiratory Insufficiency

1996
Different central opioid receptor subtype antagonists modify maltose dextrin and deprivation-induced water intake in sham feeding and sham drinking rats.
    Brain research, 1996, Nov-25, Volume: 741, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Drinking; Eating; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Deprivation

1996
Antinociceptive effect of buprenorphine in mu1-opioid receptor deficient CXBK mice.
    Life sciences, 1997, Volume: 60, Issue:22

    Topics: Animals; Buprenorphine; Male; Mice; Mice, Inbred C57BL; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Species Specificity

1997
Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism.
    Science (New York, N.Y.), 1997, Jun-27, Volume: 276, Issue:5321

    Topics: Animals; Benzoxazines; Dopamine; Dronabinol; Heroin; Male; Microdialysis; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid, mu; Rimonabant

1997
Involvement of opioid mu 1 receptors in morphine-induced conditioned place preference in rats.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:1

    Topics: Analgesics, Opioid; Animals; Body Temperature; Catalepsy; Conditioning, Operant; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, mu

1997
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21

    Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali

1997
Conditioned immunomodulation: investigations of the role of endogenous activity at mu, kappa, and delta opioid receptor subtypes.
    Journal of neuroimmunology, 1997, Volume: 79, Issue:2

    Topics: Animals; Avoidance Learning; Cell Division; Conditioning, Classical; Electroshock; Immune System; Killer Cells, Natural; Lipopolysaccharides; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Lew; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spleen

1997
Morphine-6-glucuronide-induced locomotor stimulation in mice: role of opioid receptors.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:1

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Derivatives; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid

1998
Identification of opioid receptor subtypes in antinociceptive actions of supraspinally-administered mitragynine in mice.
    Life sciences, 1998, Volume: 62, Issue:16

    Topics: Analgesics; Animals; Drug Synergism; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Receptors, Opioid; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids

1998
Respiratory and cardiovascular effects of the mu-opioid receptor agonist [Lys7]dermorphin in awake rats.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: Analgesia; Animals; Blood Pressure; Hypercapnia; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Prosencephalon; Pulmonary Ventilation; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Opioid, mu; Ritanserin; Serotonin Antagonists; Tidal Volume

1998
A dopamine-mu1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse.
    The European journal of neuroscience, 1998, Volume: 10, Issue:3

    Topics: Animals; Dopamine; Food Preferences; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance-Related Disorders; Time Factors; Ventral Tegmental Area

1998
Modulation of volitional ethanol intake in the rat by central delta-opioid receptors.
    Alcoholism, clinical and experimental research, 1998, Volume: 22, Issue:6

    Topics: Alcohol Drinking; Animals; Enkephalin, Leucine; Male; Naloxone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta

1998
Heroin antinociception changed from mu to delta receptor in streptozotocin-treated mice.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:4

    Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heroin; Injections, Intraventricular; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu; Streptozocin; Time Factors

1998
Dynorphin A increases substance P release from trigeminal primary afferent C-fibers.
    European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1

    Topics: Animals; Animals, Newborn; Capsaicin; Dizocilpine Maleate; Dynorphins; Enkephalin, Leucine; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei

1999
Contribution of spinal mu1-opioid receptors to morphine-induced antinociception.
    European journal of pharmacology, 1999, Mar-19, Volume: 369, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Drug Interactions; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Pain Measurement; Receptors, Opioid, mu; Spinal Cord

1999
Activation of opioid mu-receptor by loperamide to lower plasma glucose in streptozotocin-induced diabetic rats.
    Neuroscience letters, 1999, Apr-23, Volume: 265, Issue:3

    Topics: Animals; Antidiarrheals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Hyperglycemia; Injections, Intravenous; Loperamide; Male; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu

1999
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception.
    European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain; Receptors, Opioid, mu; Time Factors

1999
Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa.
    General pharmacology, 1999, Volume: 33, Issue:1

    Topics: Analgesics; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Plants, Medicinal; Receptors, Opioid; Secologanin Tryptamine Alkaloids; Thailand; Vas Deferens

1999
Antagonistic effects of naloxone and naloxonazine on sufentanil-induced antinociception and respiratory depression in rats.
    Pain, 1999, Volume: 83, Issue:1

    Topics: Analgesics, Opioid; Anesthesia, Spinal; Animals; Hypercapnia; Hypoxia; Injections, Intravenous; Injections, Spinal; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiration; Sufentanil

1999
Antinociceptive properties of FR140423 mediated through spinal delta-, but not mu- and kappa-, opioid receptors.
    European journal of pharmacology, 1999, Sep-10, Volume: 380, Issue:2-3

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Binding, Competitive; Diarrhea; Injections, Intraventricular; Injections, Spinal; Male; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pyrazoles; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sulfoxides

1999
The antinociceptive effects of endomorphin-1 and endomorphin-2 in diabetic mice.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2000
Inhibitory effect of intracerebroventricularly-administered [D-Arg(2), beta-Ala(4)]-dermorphin (1-4) on gastrointestinal transit.
    Peptides, 2000, Volume: 21, Issue:2

    Topics: Analgesics; Animals; Charcoal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Gastrointestinal Transit; Injections, Intraventricular; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides

2000
Selective antagonism by naloxonazine of antinociception by Tyr-D-Arg-Phe-beta-Ala, a novel dermorphin analogue with high affinity at mu-opioid receptors.
    European journal of pharmacology, 2000, Apr-28, Volume: 395, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Drug Antagonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Pain Measurement; Receptors, Opioid, mu; Time Factors

2000
Mercaptoacetate induces feeding through central opioid-mediated mechanisms in rats.
    Brain research, 2000, May-12, Volume: 864, Issue:2

    Topics: Animals; Antisense Elements (Genetics); Cloning, Molecular; Eating; Exons; Feeding Behavior; Injections, Intraperitoneal; Injections, Intraventricular; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereotyped Behavior; Thioglycolates

2000
The effects of highly selective opioid receptor antagonists on the release of arginine vasotocin induced by hyperosmotic stimulation and angiotensin II injection.
    General and comparative endocrinology, 2000, Volume: 118, Issue:3

    Topics: Angiotensin II; Animals; Chickens; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saline Solution, Hypertonic; Vasotocin

2000
Involvement of central opioid systems in human interferon-alpha induced immobility in the mouse forced swimming test.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Interferon-alpha; Interferon-beta; Interferon-gamma; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Swimming; Time Factors

2000
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Amino Acid Substitution; Animals; Benzamides; Benzomorphans; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes

2000
Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone.
    Brain research, 2000, Oct-20, Volume: 881, Issue:1

    Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heroin; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Receptors, Opioid, mu

2000
Receptor binding and biological activity of the dermorphin analog Tyr-D-Arg(2)-Phe-Sar (TAPS).
    European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2

    Topics: Analgesics; Animals; Binding, Competitive; Catalepsy; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Injections, Spinal; Male; Muscle Contraction; Naloxone; Nociceptors; Oligopeptides; Opioid Peptides; Pulmonary Ventilation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Time Factors

2001
Modulation of breathing by mu1 and mu2 opioid receptor stimulation in neonatal and adult rats.
    Respiration physiology, 2001, Volume: 127, Issue:2-3

    Topics: Age Factors; Analgesics, Opioid; Animals; Animals, Newborn; Female; Fentanyl; Lung; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiratory Mechanics; Tidal Volume

2001
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
    European journal of pharmacology, 2001, Sep-21, Volume: 427, Issue:3

    Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors

2001
Plasma glucose-lowering effect of tramadol in streptozotocin-induced diabetic rats.
    Diabetes, 2001, Volume: 50, Issue:12

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gluconeogenesis; Glucose; Glucose Transporter Type 4; Glycogen; Hypoglycemic Agents; Injections, Intravenous; Kinetics; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Narcotics; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Receptors, Opioid, mu; RNA, Messenger; Tramadol

2001
Endomorphin-1 improves scopolamine-induced impairment of short-term memory via mu1-opioid receptor in mice.
    Neuroreport, 2001, Dec-04, Volume: 12, Issue:17

    Topics: Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Receptors, Opioid, mu; Scopolamine

2001
Involvement of mu(1)-opioid receptors and cholinergic neurotransmission in the endomorphins-induced impairment of passive avoidance learning in mice.
    Behavioural brain research, 2002, Feb-01, Volume: 129, Issue:1-2

    Topics: Animals; Avoidance Learning; Cholinesterase Inhibitors; Injections, Intraventricular; Male; Memory; Mice; Naloxone; Narcotic Antagonists; Oligopeptides; Parasympathetic Nervous System; Physostigmine; Receptors, Opioid, mu; Synaptic Transmission

2002
Opioid peptides inhibit excitatory but not inhibitory synaptic transmission in the rat dorsal motor nucleus of the vagus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-15, Volume: 22, Issue:8

    Topics: Animals; Brain Stem; Digestive System; Electric Stimulation; Endorphins; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Motor Neurons; Naloxone; Narcotic Antagonists; Neural Inhibition; Opioid Peptides; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Receptors, Opioid, mu; Solitary Nucleus; Synaptic Transmission; Vagus Nerve

2002
mu-1 opioid receptor stimulation decreases body temperature in conscious, unrestrained neonatal rats.
    Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:6

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Body Temperature; Female; Fentanyl; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Temperature; Time Factors

2002
Release of beta-endorphin from adrenal gland to lower plasma glucose by the electroacupuncture at Zhongwan acupoint in rats.
    Neuroscience letters, 2002, Jun-21, Volume: 326, Issue:1

    Topics: Acupuncture Points; Adrenal Glands; Adrenalectomy; Animals; beta-Endorphin; Blood Glucose; Electroacupuncture; Hypoglycemia; Insulin; Male; Mice; Mice, Knockout; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu

2002
Differential antagonism of endomorphin-1 and endomorphin-2 supraspinal antinociception by naloxonazine and 3-methylnaltrexone.
    Peptides, 2002, Volume: 23, Issue:5

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Quaternary Ammonium Compounds; Reflex; Time Factors

2002
Lack of involvement of mu(1) opioid receptors in dermorphin-induced inhibition of hypoxic and hypercapnic ventilation in rat pups.
    Respiratory physiology & neurobiology, 2002, Aug-01, Volume: 131, Issue:3

    Topics: Age Factors; Analgesics, Opioid; Animals; Hypercapnia; Hypoxia; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Oxygen; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiratory Mechanics

2002
Possible involvement of mu1-opioid receptors in the fentanyl- or morphine-induced antinociception at supraspinal and spinal sites.
    Life sciences, 2002, Apr-05, Volume: 70, Issue:20

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, mu; Spinal Cord

2002
Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:3

    Topics: Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Cues; Discrimination, Psychological; Ethanol; Extinction, Psychological; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration

2002
Effects of the selective mu(1)-opioid receptor antagonist, naloxonazine, on cocaine-induced conditioned place preference and locomotor behavior in rats.
    Neuroscience letters, 2002, Nov-08, Volume: 332, Issue:3

    Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward

2002
Plasma glucose-lowering effect of beta-endorphin in streptozotocin-induced diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2002, Volume: 34, Issue:10

    Topics: Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose; Hepatocytes; In Vitro Techniques; Male; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu

2002
Effects of beta-funaltrexamine and naloxonazine on single-trial morphine-conditioned place preference and locomotor activity.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:3

    Topics: Animals; Conditioning, Psychological; Male; Morphine; Motor Activity; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2003
Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:2

    Topics: Analgesics, Opioid; Animals; Antibodies, Blocking; Cloning, Molecular; Dynorphins; Endorphins; Enkephalin, Methionine; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Radioligand Assay; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2003
The antitussive effects of endomorphin-1 and endomorphin-2 in mice.
    European journal of pharmacology, 2003, Apr-25, Volume: 467, Issue:1-3

    Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid, kappa; Receptors, Opioid, mu

2003
Micro1-opioid antagonist naloxonazine alters ethanol discrimination and consumption.
    Alcohol (Fayetteville, N.Y.), 2003, Volume: 29, Issue:2

    Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Discrimination, Psychological; Dose-Response Relationship, Drug; Eating; Ethanol; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2003
Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of mu(1)- and kappa-opioid receptor blockade on escape behavior induced by electrical stimulation of the inferior colliculus.
    Brain research, 2003, Dec-05, Volume: 992, Issue:2

    Topics: Animals; Biotin; Dextrans; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Fear; Inferior Colliculi; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Periaqueductal Gray; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu

2003
Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Analgesics, Opioid; Animals; Electric Stimulation; Female; Hot Temperature; Injections, Spinal; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Pathways; Nociceptors; Raphe Nuclei; Rats; Rats, Sprague-Dawley

2004
Differential involvement of mu 1-opioid receptors in dermorphin tetrapeptide analogues-induced antinociception.
    European journal of pharmacology, 2004, Feb-13, Volume: 486, Issue:1

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Male; Mice; Naloxone; Oligopeptides; Pain Measurement; Receptors, Opioid, mu

2004
Supraspinal anti-allodynic and rewarding effects of endomorphins in rats.
    Peptides, 2004, Volume: 25, Issue:4

    Topics: Analgesics, Opioid; Animals; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Compression Syndromes; Oligopeptides; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley

2004
Depressor and bradycardic responses to microinjections of endomorphin-2 into the NTS are mediated via ionotropic glutamate receptors.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:4

    Topics: Analgesics, Opioid; Animals; Blood Pressure; Dose-Response Relationship, Drug; GABA Antagonists; Heart Rate; Male; Microinjections; Naloxone; Narcotic Antagonists; Oligopeptides; Parasympathetic Nervous System; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Stereotaxic Techniques; Vagus Nerve

2004
The cardiovascular and renal effects of the potent and highly selective mu opioid agonist [Dmt1]DALDA.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:6

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Enzyme Inhibitors; Female; Gene Expression; Heart Rate; Hemodynamics; Homeostasis; Kidney; Myocardium; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Vasopressins

2004
A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu

2005
Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouse.
    European journal of pharmacology, 2005, Feb-10, Volume: 509, Issue:1

    Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hot Temperature; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Nociceptors; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu; Tail; Time Factors

2005
Attenuation of aortic baroreflex responses by microinjections of endomorphin-2 into the rostral ventrolateral medullary pressor area of the rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 289, Issue:1

    Topics: Animals; Aorta; Baroreflex; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Male; Medulla Oblongata; Microinjections; Naloxone; Nervous System Physiological Phenomena; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Vagus Nerve

2005
Effect of the blockade of mu1-opioid and 5HT2A-serotonergic/alpha1-noradrenergic receptors on sweet-substance-induced analgesia.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesia; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Methysergide; Naloxone; Naltrexone; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Serotonin Antagonists; Sucrose; Taste

2005
Mu opiate active substances trefentanil and naloxonazine: tritiation at high specific activity.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2005, Volume: 63, Issue:2

    Topics: Isotope Labeling; Magnetic Resonance Spectroscopy; Naloxone; Piperidines; Radiopharmaceuticals; Receptors, Opioid, mu; Tetrazoles; Tritium

2005
Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways: involvement of GABAA and mu1-opioid receptors in the modulation of panic-like reactions elicited b
    Journal of chemical neuroanatomy, 2005, Volume: 30, Issue:4

    Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; Male; Mesencephalon; Microscopy, Electron; Naloxone; Narcotic Antagonists; Neural Pathways; Neurons; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, mu; Substantia Nigra; Tectum Mesencephali

2005
The role of opioid receptor subtypes in the development of behavioral sensitization to ethanol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:7

    Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Somatostatin; Time Factors

2006
Effects of systemic administration of beta-casomorphin-5 on learning and memory in mice.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Analgesics; Animals; Avoidance Learning; Cattle; Dose-Response Relationship, Drug; Endorphins; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Memory; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid, mu; Scopolamine

2006
Novel mechanism for plasma glucose-lowering action of metformin in streptozotocin-induced diabetic rats.
    Diabetes, 2006, Volume: 55, Issue:3

    Topics: Adrenalectomy; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Hypoglycemic Agents; Male; Metformin; Mice; Naloxone; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Streptozocin

2006
Modulation of anxiety by mu-opioid receptors of the lateral septal region in mice.
    Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:3

    Topics: Animals; Anxiety; gamma-Aminobutyric Acid; Male; Maze Learning; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Septal Nuclei

2006
The effects of endomorphins and diprotin A on striatal dopamine release induced by electrical stimulation-an in vitro superfusion study in rats.
    Neurochemistry international, 2006, Volume: 49, Issue:7

    Topics: Animals; Corpus Striatum; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dopamine; Electric Stimulation; Infusion Pumps; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Oligopeptides; Organ Culture Techniques; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Wistar; Substantia Nigra; Synaptic Transmission

2006
Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway.
    Biomedical research (Tokyo, Japan), 2006, Volume: 27, Issue:6

    Topics: Animals; Appetite Regulation; Corn Oil; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides, Bacterial; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction

2006
Involvement of mu1-opioid receptor on oxycodone-induced antinociception in diabetic mice.
    European journal of pharmacology, 2007, Apr-10, Volume: 560, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oxycodone; Receptors, Opioid, mu; Streptozocin

2007
Structural determination of the novel fragmentation routes of zwitteronic morphine opiate antagonists naloxonazine and naloxone hydrochlorides using electrospray ionization tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:6

    Topics: Computer Simulation; Models, Chemical; Models, Molecular; Morphine; Naloxone; Opioid Peptides; Spectrometry, Mass, Electrospray Ionization

2007
Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis.
    Biological psychiatry, 2007, Sep-15, Volume: 62, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Animals; Basal Ganglia; Disease Models, Animal; Dopamine; Epistasis, Genetic; Ethanol; Genotype; Humans; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Naloxone; Nucleus Accumbens; Receptors, Opioid, mu; Reinforcement, Psychology; Sex Characteristics

2007
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
    European journal of pharmacology, 2007, Jun-01, Volume: 563, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hot Temperature; Injections, Intraventricular; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Reaction Time; Receptors, Opioid, mu; Somatostatin; Time Factors

2007
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4-11), mammalian tachykinin peptides, on the modulation of pain in mice.
    Brain, behavior, and immunity, 2008, Volume: 22, Issue:6

    Topics: Analgesics; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Humans; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Tachykinins; Tropanes

2008
Evidence for separate involvement of different mu-opioid receptor subtypes in itch and analgesia induced by supraspinal action of opioids.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Naloxone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Pruritus; Receptors, Opioid, mu; Time Factors

2008
Possible involvement of dynorphin A release via mu1-opioid receptor on supraspinal antinociception of endomorphin-2.
    Peptides, 2008, Volume: 29, Issue:9

    Topics: Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Immune Sera; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu

2008
A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating.
    Brain research, 2008, Nov-13, Volume: 1240

    Topics: Analgesics, Opioid; Animals; Autoradiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Feeding Behavior; Guanosine 5'-O-(3-Thiotriphosphate); Male; Naloxone; Pons; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2008
The effects of endomorphins on striatal [3H]GABA release induced by electrical stimulation: an in vitro superfusion study in rats.
    Neurochemical research, 2009, Volume: 34, Issue:5

    Topics: Animals; Corpus Striatum; Dipeptidyl-Peptidase IV Inhibitors; Electric Stimulation; gamma-Aminobutyric Acid; Male; Naloxone; Naltrexone; Oligopeptides; Perfusion; Rats; Rats, Wistar; Receptors, Opioid, mu; Tritium

2009
Intravenous self-administration of etonitazene alone and combined with cocaine in rhesus monkeys: comparison with heroin and antagonism by naltrexone and naloxonazine.
    Psychopharmacology, 2009, Volume: 204, Issue:3

    Topics: Animals; Benzimidazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Female; Heroin; Injections, Intravenous; Macaca mulatta; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Substance Abuse, Intravenous

2009
Opioid antagonist-induced regulation of the mu-opioid receptor expression in MCF-7 breast cancer cell line.
    Endocrine regulations, 2009, Volume: 43, Issue:1

    Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Estradiol; Humans; Naloxone; Narcotic Antagonists; Polymerase Chain Reaction; Receptors, Opioid, mu; RNA, Messenger; Up-Regulation

2009
Selective mu- and kappa-opioid receptor antagonists administered into the nucleus accumbens interfere with rapid tolerance to ethanol in rats.
    Psychopharmacology, 2009, Volume: 206, Issue:1

    Topics: Animals; Drug Tolerance; Ethanol; Male; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu

2009
Mediation of protein kinase C zeta in mu-opioid receptor activation for increase of glucose uptake into cultured myoblast C2C12 cells.
    Neuroscience letters, 2009, Nov-13, Volume: 465, Issue:2

    Topics: Animals; Blotting, Western; Carbon Radioisotopes; Cell Line; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Indoles; Loperamide; Maleimides; Mice; Myoblasts, Skeletal; Naloxone; Narcotic Antagonists; Phosphorylation; Protein Kinase C; Receptors, Opioid, mu

2009
Effect of opioid compounds on feeding and activity of the cockroach, Periplaneta americana.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2010, Volume: 151, Issue:3

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cockroaches; Eating; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Loss, Insensible

2010
Opioid-salsolinol relationship in the control of prolactin release during lactation.
    Neuroscience, 2010, Nov-10, Volume: 170, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Suckling; Brain; Dopamine; Female; Isoquinolines; Lactation; Naloxone; Narcotic Antagonists; Prolactin; Receptors, Opioid, mu; Sheep

2010
Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model.
    Peptides, 2010, Volume: 31, Issue:11

    Topics: Analgesics; Animals; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Peptides, Cyclic; Receptors, Opioid, mu

2010
Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors.
    Neurourology and urodynamics, 2011, Volume: 30, Issue:3

    Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Loperamide; Male; Muscle Relaxation; Naloxone; Narcotic Antagonists; Potassium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Prostate; Rats; Rats, Wistar; Receptors, Opioid, mu

2011
Effect of a nanostructured dendrimer-naloxonazine complex on endogenous opioid peptides μ1 receptor-mediated post-ictal antinociception.
    Nanomedicine : nanotechnology, biology, and medicine, 2011, Volume: 7, Issue:6

    Topics: Analgesia; Animals; Dendrimers; Drug Carriers; Male; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Polypropylenes; Rats; Rats, Wistar; Receptors, Opioid, mu; Seizures

2011
Activation of peripheral opioid µ-receptors in blood vessel may lower blood pressure in spontaneously hypertensive rats.
    Pharmacology, 2011, Volume: 87, Issue:5-6

    Topics: Animals; Arteries; Blood Pressure; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium; Glyburide; Hemodynamics; Intracellular Signaling Peptides and Proteins; KATP Channels; Loperamide; Male; Morphinans; Naloxone; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid, mu; Vasodilation

2011
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens.
    Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:8

    Topics: Acetaldehyde; Animals; Enzyme Activation; Ethanol; Extracellular Signal-Regulated MAP Kinases; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Wistar; Receptors, Opioid, mu; Reinforcement, Psychology; Saccharin; Self Administration

2011
A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:7

    Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Drug Discovery; High-Throughput Screening Assays; Host-Parasite Interactions; Humans; Leishmania; Leishmaniasis; Life Cycle Stages; Macrophages; Naloxone; Small Molecule Libraries

2011
Inhibition of motility in isolated horse small intestine is mediated by κ but not µ opioid receptors.
    Equine veterinary journal, 2012, Volume: 44, Issue:3

    Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Dose-Response Relationship, Drug; Fentanyl; Gastrointestinal Motility; Horses; Intestine, Small; Male; Morphine; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu

2012
Endogenous opioid peptide-mediated neurotransmission in central and pericentral nuclei of the inferior colliculus recruits μ1-opioid receptor to modulate post-ictal antinociception.
    Neuropeptides, 2012, Volume: 46, Issue:1

    Topics: Animals; Inferior Colliculi; Male; Naloxone; Opioid Peptides; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Opioid, mu; Seizures; Synaptic Transmission

2012
YFa and analogs: investigation of opioid receptors in smooth muscle contraction.
    World journal of gastroenterology, 2011, Oct-28, Volume: 17, Issue:40

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Cholinergic Agonists; Dynorphins; Enkephalin, Methionine; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Oligopeptides; Receptors, Opioid; Vas Deferens

2011
Regulation of growth hormone secretion in nursing ewes: an involvement of μ-receptor subtype.
    Reproduction in domestic animals = Zuchthygiene, 2012, Volume: 47, Issue:5

    Topics: Animals; Female; Growth Hormone; Guanidines; Infusions, Intraventricular; Lactation; Morphinans; Naloxone; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep

2012
Opiate-induced constipation related to activation of small intestine opioid μ2-receptors.
    World journal of gastroenterology, 2012, Mar-28, Volume: 18, Issue:12

    Topics: Acetylcholine; Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gastrointestinal Transit; Glyburide; Humans; Intestine, Small; Loperamide; Male; Mice; Mice, Inbred BALB C; Morphinans; Muscle Relaxation; Naloxone; Receptors, Opioid, mu

2012
Naloxonazine, a specific mu-opioid receptor antagonist, attenuates the increment of locomotor activity induced by acute methamphetamine in mice.
    Toxicology letters, 2012, Jul-07, Volume: 212, Issue:1

    Topics: Animals; Blotting, Western; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Interactions; Male; Methamphetamine; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Narcotic Antagonists; Phosphorylation; Receptors, Opioid, mu; Video Recording

2012
μ1- and 5-HT1-dependent mechanisms in the anterior pretectal nucleus mediate the antinociceptive effects of retrosplenial cortex stimulation in rats.
    Life sciences, 2012, Jun-14, Volume: 90, Issue:23-24

    Topics: Animals; Atropine; Cerebral Cortex; Cobalt; Disease Models, Animal; Electric Stimulation Therapy; Male; Methiothepin; Naloxone; Pain Management; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT1

2012
Antinociceptive action of isolated mitragynine from Mitragyna Speciosa through activation of opioid receptor system.
    International journal of molecular sciences, 2012, Volume: 13, Issue:9

    Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Male; Mice; Mice, Inbred ICR; Mitragyna; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Opioid; Secologanin Tryptamine Alkaloids

2012
Involvement of μ-opioid receptors in antinociceptive action of botulinum toxin type A.
    Neuropharmacology, 2013, Volume: 70

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Naltrexone; Narcotic Antagonists; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Receptors, Opioid, mu

2013
Involvement of supraspinal and peripheral naloxonazine-insensitive opioid receptor sites in the expression of μ-opioid receptor agonist-induced physical dependence.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Animals; Free Radicals; Male; Mice; Naloxone; Peripheral Nervous System; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Substance-Related Disorders

2013
Different types of opioid receptors involved in the suppression of LH secretion in lactating sheep.
    Animal reproduction science, 2013, Volume: 141, Issue:1-2

    Topics: Animals; Female; Gene Expression Regulation; Guanidines; Lactation; Luteinizing Hormone; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Sheep

2013
Involvement of spinal release of α-neo-endorphin on the antinociceptive effect of TAPA.
    Peptides, 2013, Volume: 50

    Topics: Analgesia; Analgesics, Opioid; Animals; Endorphins; Gene Expression; Immune Sera; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Tail

2013
The opioid system majorly contributes to preference for fat emulsions but not sucrose solutions in mice.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:4

    Topics: Administration, Oral; Animals; Behavior, Animal; Choice Behavior; Dietary Fats; Eating; Emulsions; Food Preferences; Male; Mice; Mice, Inbred BALB C; Naloxone; Naltrexone; Narcotic Antagonists; Phospholipids; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Soybean Oil; Sucrose

2015
Prenatal exposure to vanilla or alcohol induces crawling after these odors in the neonate rat: The role of mu and kappa opioid receptor systems.
    Physiology & behavior, 2015, Sep-01, Volume: 148

    Topics: Analysis of Variance; Animals; Animals, Newborn; Drug-Seeking Behavior; Ethanol; Female; Locomotion; Maternal Exposure; Naloxone; Naltrexone; Odorants; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Vanilla

2015
Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jul-01, Volume: 35, Issue:26

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Astrocytes; Buprenorphine; Dose-Response Relationship, Drug; Hyperalgesia; In Vitro Techniques; Male; Naloxone; Nerve Fibers, Unmyelinated; Pain Measurement; Pain Threshold; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Spinal Nerve Roots; Synapses; Time Factors

2015
Antinociceptive action of botulinum toxin type A in carrageenan-induced mirror pain.
    Journal of neural transmission (Vienna, Austria : 1996), 2016, Volume: 123, Issue:12

    Topics: Analgesics; Animals; Bicuculline; Botulinum Toxins, Type A; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Functional Laterality; Hyperalgesia; Male; Naloxone; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Cord; Synaptosomal-Associated Protein 25

2016
Opioid system mediated anti-nociceptive effect of agomelatine in mice.
    Life sciences, 2016, Oct-15, Volume: 163

    Topics: Acetamides; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Naltrexone; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rotarod Performance Test

2016
Endogenous central amygdala mu-opioid receptor signaling promotes sodium appetite in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 11-29, Volume: 113, Issue:48

    Topics: Analgesics, Opioid; Animals; Appetite; Brain Mapping; Central Amygdaloid Nucleus; Mice; Naloxone; Neurons; Receptors, Opioid, mu; Signal Transduction; Sodium, Dietary

2016
Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:12

    Topics: Animals; Host-Parasite Interactions; Humans; Leishmania donovani; Leishmaniasis; Macrolides; Macrophages; Naloxone; RNA, Small Interfering; Tissue Array Analysis; Vacuolar Proton-Translocating ATPases; Vacuoles

2016
Opioid system contribution to the antidepressant-like action of m-trifluoromethyl-diphenyl diselenide in mice: A compound devoid of tolerance and withdrawal syndrome.
    Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:9

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Organosilicon Compounds; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Swimming

2017
Panicolytic-like effect of µ
    Journal of psychopharmacology (Oxford, England), 2019, Volume: 33, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Crotalus; Disease Models, Animal; Fear; Food Chain; Inferior Colliculi; Naloxone; Narcotic Antagonists; Panic Disorder; Rats; Rats, Wistar; Receptors, Opioid, mu; Signal Transduction

2019
The Blockade of µ1- and κ-Opioid Receptors in the Inferior Colliculus Decreases the Expression of Panic Attack-Like Behaviours Induced by Chemical Stimulation of the Dorsal Midbrain.
    Neuropsychobiology, 2019, Volume: 78, Issue:4

    Topics: Animals; Behavior, Animal; Bicuculline; Exploratory Behavior; GABA-A Receptor Antagonists; Inferior Colliculi; Male; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Panic; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu

2019
Contribution of the μ opioid receptor and enkephalin to the antinociceptive actions of endomorphin-1 analogs with unnatural amino acid modifications in the spinal cord.
    Peptides, 2021, Volume: 141

    Topics: Analgesics; Animals; Chronic Pain; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Mice; Naloxone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu; Spinal Cord

2021
The blockade of μ‑opioid receptors in the lateral hypothalamus enhances panic attack‑like behaviour and diminishes defensive antinociception.
    Acta neurobiologiae experimentalis, 2022, Volume: 82, Issue:2

    Topics: Animals; Behavior, Animal; Bicuculline; Fear; Hypothalamic Area, Lateral; Naloxone; Narcotic Antagonists; Nociception; Panic; Panic Disorder; Rats; Rats, Wistar; Receptors, Opioid, mu

2022