naloxonazine has been researched along with naloxone in 196 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 33 (16.84) | 18.7374 |
1990's | 71 (36.22) | 18.2507 |
2000's | 59 (30.10) | 29.6817 |
2010's | 31 (15.82) | 24.3611 |
2020's | 2 (1.02) | 2.80 |
Authors | Studies |
---|---|
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
Briddon, SJ; Canals, M; Graham, B; Kellam, B; Scammells, PJ; Schembri, LS; Stoddart, LA | 1 |
Childers, SR; Nijssen, PC; Sexton, T | 1 |
Feuerstein, G; Paakkari, I; Paakkari, P; Sirén, AL | 2 |
Larson, AA; Mousseau, DD; Sun, X | 1 |
Cheng, PY; Cheng, Y; Decena, JA; Szeto, HH; Wu, DL | 1 |
Jang, Y; Yoburn, BC | 1 |
Baumann, MH; Rabii, J | 1 |
Pasternak, GW; Paul, D; Pick, CG | 1 |
Feuerstein, G; Paakkari, I; Paakkari, P | 1 |
Bridges, RS; Mann, PE; Pasternak, GW | 1 |
Goodman, RR; Hahn, EF; Nishimura, S; Pasternak, GW | 1 |
Liang, CS; Sakamoto, S | 1 |
Bodnar, RJ; Gistrak, MA; Pasternak, GW; Paul, D | 1 |
Heyman, JS; Jiang, Q; Mosberg, HI; Porreca, F; Rothman, RB | 1 |
Inturrisi, CE; Pasternak, GW; Paul, D; Standifer, KM | 1 |
Burks, TF; Heyman, JS; Mosberg, HI; Porreca, F; Williams, CL | 1 |
Pasternak, GW; Paul, D | 1 |
Pasternak, GW; Wood, PJ | 1 |
Arjune, D; Bodnar, RJ; Hahn, EF; Mann, PE; Pasternak, GW; Romero, MT | 1 |
Clark, JA; Houghten, R; Pasternak, GW | 1 |
Ling, GS; Lockhart, SH; Pasternak, GW; Spiegel, K | 1 |
Bodnar, RJ; Goldman, EJ; Pasternak, GW; Simone, DA | 1 |
Bodnar, RJ; Pasternak, GW; Portzline, T; Simone, DA | 1 |
Chang, JK; Huang, XH; Lu, WX; Mo, WY; Xu, SF; Xu, WM; Zhang, AZ; Zhou, KR | 1 |
Clark, JA; Ling, GS; Pasternak, GW; Simantov, R | 1 |
Itzhak, Y; Pasternak, GW | 1 |
Dray, A; Nunan, L; Wire, W | 1 |
Duffy, P; Kalivas, PW; Latimer, LG | 1 |
Cruciani, RA; Lutz, RA; Munson, PJ; Rodbard, D | 1 |
Bodnar, RJ; Curreri, G; Hahn, EF; Lubin, E; Mann, PE; Pasternak, GW | 1 |
Chang, JK; He, XP; Lu, WX; Niu, SF; Weber, E; Xu, SF; Xu, WM; Zhang, AZ; Zhou, KR | 1 |
Gmerek, DE; Woods, JH | 1 |
Itzhak, Y; Johnson, N; Pasternak, GW | 1 |
Houghten, RA; Johnson, N; Pasternak, GW | 1 |
Johnson, N; Pasternak, GW | 2 |
Dray, A; Nunan, L | 1 |
Rourke, JD; Shaw, JS | 1 |
Carroll-Buatti, M; Hahn, EF; Pasternak, GW | 1 |
Ling, GS; Nishimura, SL; Pasternak, GW; Spiegel, K | 1 |
Pasternak, GW; Wood, PL | 1 |
Gintzler, AR; Pasternak, GW | 1 |
Lee, S; Ling, GS; Lockhart, SH; MacLeod, JM; Pasternak, GW | 1 |
Garzón, J; Sánchez-Blázquez, P | 1 |
Kamei, J; Morita, K; Nagase, H; Saitoh, A | 2 |
Bodnar, RJ; Cole, JL; Kirkham, TC; Leventhal, L | 1 |
Bodnar, RJ; Bowen, WD; Cole, JL; Leventhal, L; Pasternak, GW | 1 |
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M; Saitoh, A; Suzuki, T | 1 |
Traynor, JR | 1 |
Bodnar, RJ; Glass, MJ; Koch, JE | 1 |
Kromer, W | 1 |
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T | 1 |
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M | 2 |
Elliott, J; Lambert, DG; Smart, D; Traynor, JR | 2 |
Bodnar, RJ; Glass, MJ; Hahn, B; Joseph, A | 1 |
Broccardo, M; Improta, G | 1 |
Búzás, B; Cox, BM; Izenwasser, S | 1 |
Kwok, YN; McIntosh, C; Yago, V | 1 |
Hitosugi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H | 1 |
Eisenberg, RM | 2 |
Imai, N; Kashiki, M; Liang, CS; Woolf, PD | 1 |
Randich, A; Robertson, JD; Willingham, T | 1 |
Callahan, P; Janik, J; Rabii, J | 1 |
Cheng, PY; Decena, J; McCabe, S; Soong, Y; Szeto, HH; Wu, D | 1 |
Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T | 1 |
Bodnar, RJ; Koch, JE | 1 |
Nejat, RJ; Pasternak, GW; Pick, CG | 1 |
Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Nagase, H; Suzuki, T | 1 |
Henriksen, SJ; Koob, GF; Mattox, A; Negus, SS; Pasternak, GW; Portoghese, PS; Takemori, AE; Weinger, MB | 1 |
Plotsky, PM; Rivest, S; Rivier, C | 1 |
Feuerstein, G; Paakkari, I; Paakkari, P; Sirén, AL; Vonhof, S | 1 |
Cheng, PY; Decena, JA; McCabe, S; Soong, Y; Szeto, HH; Wu, D | 1 |
Beczkowska, IW; Bodnar, RJ; Bostock, ME; Koch, JE; Leibowitz, SF | 1 |
Koob, GF; Negus, SS; Pasternak, GW; Weinger, MB | 1 |
Misawa, M; Mori, T; Nagase, H; Suzuki, T; Tsuji, M | 1 |
Negri, L; Noviello, L; Noviello, V | 1 |
Honkanen, A; Hyytiä, P; Korpi, ER; Sarviharju, M; Vilamo, L; Wegelius, K | 1 |
Bergman, J; Gatch, MB; Liguori, A; Liguori, T; Mello, NK; Negus, SS | 1 |
Bodnar, RJ; Cole, JL; Leventhal, L | 1 |
Ahtee, L; Piepponen, TP | 1 |
Beatty, MF; Chen, SW; Davies, MF; Loew, GH; Maguire, PA | 1 |
Bodnar, RJ; Leventhal, L | 1 |
Kamei, J; Nagase, H; Sodeyama, M; Suzuki, T; Tsuda, M | 1 |
Di Chiara, G; Pontieri, FE; Tanda, G | 1 |
Ahtee, L; Katajamäki, J; Kivastik, T; Piepponen, TP; Zharkovsky, A | 1 |
Bontempi, B; Sharp, FR | 1 |
Lysle, DT; Perez, L | 1 |
Aasmundstad, TA; Alkana, RL; Grung, M; Handal, M; Mørland, J; Skurtveit, S | 1 |
Aimi, N; Matsumoto, K; Sakai, S; Takayama, H; Thongpradichote, S; Tohda, M; Watanabe, H | 1 |
Lattanzi, R; Melchiorri, P; Negri, L; Tabacco, F | 1 |
Di Chiara, G; Tanda, G | 1 |
Franck, J; Lindholm, S; Raaschou, P | 1 |
Fujimoto, JM; Gorny, JM; Rady, JJ | 1 |
Arcaya, JL; Cano, G; Gómez, G; Maixner, W; Suárez-Roca, H | 1 |
Kisara, K; Sakurada, S; Sakurada, T; Sato, T; Takahashi, N; Tan-No, K; Wako, K | 1 |
Chen, YC; Cheng, JT; Chi, TC; Liu, IM; Lu, FH | 1 |
Fujimura, T; Kastin, AJ; Katsuyama, S; Murayama, K; Sakurada, S; Sakurada, T; Ueda, H; Yuki, M; Zadina, JE | 1 |
Aimi, N; Horie, S; Pang, PK; Ponglux, D; Sakai, S; Shan, J; Takayama, H; Watanabe, K; Yamamoto, LT; Yano, S | 1 |
Meert, TF; Verborgh, C | 1 |
Fujii, T; Goto, T; Motoyama, Y; Ochi, T | 1 |
Kamei, J; Nagase, H; Ohsawa, M; Zushida, K | 1 |
Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, S; Tadano, T; Takahashi, N; Tan-No, K; Yonezawa, A | 1 |
Hayashi, T; Kisara, K; Kutsuwa, M; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeda, S; Tan-No, K; Yuki, M | 1 |
Baumer, F; Bodnar, RJ; Pasternak, GW; Rossi, GC; Stein, JA; Znamensky, V | 1 |
Arakawa, K; Saito, N; Sasaki, T; Shimada, K | 1 |
Hirohashi, M; Kitano, Y; Komiyama, C; Makino, M; Takasuna, K | 1 |
Akil, H; Bonner, G; Meng, F | 1 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE | 1 |
Barone, FC; Feuerstein, GZ; Millison, JH; Paakkari, P; Price, WJ; Sirén, AK; Vonhof, S | 1 |
Pasternak, GW | 1 |
Colman, AS; Miller, JH | 3 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE | 1 |
Chang, CJ; Cheng, JT; Chi, TC; Liu, IM; Lu, FH; Tzeng, TF | 1 |
Katoh, T; Mamiya, T; Ukai, M | 1 |
Lin, HP; Ukai, M | 1 |
Browning, KN; Kalyuzhny, AE; Travagli, RA | 1 |
Chang, SL; Cheng, JT; Lin, JG | 1 |
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE | 1 |
Imai, S; Itou, Y; Narita, M; Suzuki, T; Yajima, Y | 1 |
Ciccocioppo, R; Martin-Fardon, R; Weiss, F | 1 |
Rademacher, DJ; Steinpreis, RE | 1 |
Cheng, JT; Lai, TY; Liu, IM; Tsai, CC; Tzeng, TF | 1 |
Bardo, MT; Gehrke, BJ; Rauhut, AS; Shortridge, BE | 1 |
Qian, X; Soong, Y; Szeto, HH; Wu, D; Zhao, GM | 1 |
Holloway, F; Mhatre, M | 1 |
Calvo, F; Carvalho, AD; Castellan-Baldan, L; Coimbra, NC; da Silva, LA; de Oliveira, R; Elias-Filho, DH; Felippotti, TT; Motta, V; Osaki, MY; Paschoalin-Maurin, T; Ubiali, WA | 1 |
Laurito, CE; Lu, Y; Sweitzer, SM; Yeomans, DC | 1 |
Hayashi, T; Mizoguchi, H; Sakurada, C; Sakurada, S; Sakurada, T; Watanabe, H; Yonezawa, A; Yuhki, M | 1 |
Chen, CM; Huang, EY; Tao, PL | 1 |
Chitravanshi, VC; Kasamatsu, K; Sapru, HN | 1 |
Gutkowska, J; Jankowski, M; Mukaddam-Daher, S; Schiller, PW | 1 |
Fujimura, T; Ito, K; Kawamura, S; Mizoguchi, H; Murayama, K; Nakayama, D; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H | 1 |
Ambo, A; Bryant, SD; Fujita, Y; Jinsmaa, Y; Lazarus, LH; Li, T; Miyazaki, A; Okada, Y; Sasaki, Y; Shiotani, K; Tsuda, Y | 1 |
Kasamatsu, K; Sapru, HN | 1 |
Coimbra, NC; Freitas, RL; Kishi, R; Morato, S; Rebouças, EC; Savoldi, M; Segato, EN | 1 |
Ahern, DG; Egan, JA; Filer, CN; Seguin, RJ | 1 |
Carvalho, AD; Castellan-Baldan, L; Ciscato, JG; Coimbra, NC; Corrêa, SA; D'Angelo-Dias, R; de Oliveira, R; de Oliveira, RC; Felippotti, TT; Hoffmann, A; Moreira, JE; Rebouças, EC; Ribeiro, SJ | 1 |
Aragon, CM; Pastor, R | 1 |
Koseki, M; Matsumura, E; Sakaguchi, M; Wakamatsu, M | 1 |
Chang, CJ; Cheng, JT; Huang, CC; Liu, IM; Tzeng, TF | 1 |
Cagniard, B; Cazala, P; Le Merrer, J | 1 |
Bagosi, Z; Bujdosó, E; Jászberényi, M; Szabó, G; Telegdy, G | 1 |
Fushiki, T; Inoue, K; Matsumura, S; Mizushige, T; Tsuzuki, S; Yoneda, T | 1 |
Kamei, J; Nozaki, C | 1 |
Banoub, J; Cohen, AM; El Essassi, M; Joly, N; Martin, P; Massoui, M; Vaillant, C | 1 |
Bergeson, SE; Gonzales, RA; Hall, FS; Job, MO; Sora, I; Tang, A; Uhl, GR | 1 |
Mizoguchi, H; Nakayama, D; Sakurada, S; Sakurada, T; Watanabe, C; Watanabe, H | 1 |
Chen, Q; Dong, L; Fu, CY; Ni, JM; Wang, R; Zhao, YL | 1 |
Andoh, T; Konno, M; Kuraishi, Y; Nemoto, H; Nojima, H; Takahata, H; Yageta, Y; Yamaguchi-Miyamoto, T | 1 |
Komatsu, T; Mizoguchi, H; Morimoto, M; Sakurada, S; Sakurada, T; Sato, T; Sawai, T; Watanabe, C; Watanabe, H; Yonezawa, A | 1 |
Aloyo, VJ; Chaijale, NN; Simansky, KJ | 1 |
Bagosi, Z; Jászberényi, M; Telegdy, G | 1 |
Achat-Mendes, C; Platt, DM; Rowlett, JK; Spealman, RD; Valdez, GR | 1 |
Fichna, J; Gach, K; Janecka, A; Piestrzeniewicz, M; Szemraj, J | 1 |
Morato, GS; Varaschin, RK | 1 |
Cheng, JT; Liu, IM; Wu, HT; Yang, TT | 1 |
Cooper, PD; Cowlings, A; Dennis, SR; Donnelly, C; Woodman, JD | 1 |
Górski, K; Misztal, T; Romanowicz, K; Tomaszewska-Zaremba, D | 1 |
Baiula, M; Bedini, A; De Marco, R; Gentilucci, L; Spampinato, S; Tolomelli, A | 1 |
Chen, IH; Cheng, JT; Tong, YC; Yu, BC | 1 |
Bicalho, Ude O; Coimbra, NC; do Carmo, DR; Felippotti, TT; Fraceto, LF; Grillo, R; Paim, LL; Parada, CA; Stradiotto, NR | 1 |
Chen, ZC; Cheng, JT; Chung, HH; Hung, CH; Lin, HJ; Shieh, JP | 1 |
Acquas, E; Fois, GR; Muggironi, G; Peana, AT; Vinci, S; Zinellu, M | 1 |
Ang, KK; Arkin, MR; Chen, S; De Muylder, G; Engel, JC; McKerrow, JH | 1 |
Bertini, S; Menozzi, A; Poli, E; Pozzoli, C; Serventi, P; Zullian, C | 1 |
Coimbra, NC; de Freitas, RL; Felippotti, TT | 1 |
Goyal, R; Kumar, K; Mohan, A; Mudgal, A; Pasha, S | 1 |
Dobek, E; Górski, K; Misztal, T; Molik, E; Romanowicz, K | 1 |
Chen, W; Cheng, JT; Chung, HH | 1 |
Chien, CC; Fan, LW; Ho, IK; Lee, YJ; Tien, LT | 1 |
Prado, WA; Reis, GM; Rossaneis, AC; Silveira, JW | 1 |
Arulselvan, P; Fakurazi, S; Hairuszah, I; Hidayat, MT; Moklas, MAM; Shamima, AR | 1 |
Bach-Rojecky, L; Drinovac, V; Lacković, Z; Matak, I | 1 |
Aoki, S; Inoue, K; Itoh, T; Komiya, S; Mori, T; Shibasaki, M; Suzuki, T; Uzawa, N | 1 |
Dobek, E; Górski, K; Misztal, T; Romanowicz, K | 1 |
Kon-No, T; Mizoguchi, H; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H; Yonezawa, A | 1 |
Adachi, S; Fushiki, T; Inoue, K; Matsumura, S; Okafuji, Y; Okahashi, T; Sakamoto, K; Tsuzuki, S | 1 |
Aranda-Fernández, PE; Chotro, MG; Gaztañaga, M | 1 |
Drdla-Schutting, R; Forsthuber, L; Gerhold, KJ; Honsek, SD; Sandkühler, J | 1 |
Bach-Rojecky, L; Drinovac Vlah, V; Lacković, Z | 1 |
Can, ÖD; Kasap, M | 1 |
Denton, DA; Lawrence, AJ; Leeboonngam, T; McKinley, MJ; Smith, CM; Walker, LL | 1 |
Caljon, G; De Muylder, G; Dujardin, JC; McKerrow, J; Vanhollebeke, B; Wolfe, AR | 1 |
da Luz, SC; Nogueira, CW; Pesarico, AP; Rosa, SG; Tagliapietra, CF | 1 |
Almada, RC; Bazaglia-de-Sousa, G; Calvo, F; Coimbra, NC; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Lobão-Soares, B; Medeiros, P; Paschoalin-Maurin, T; Silva, JAD | 1 |
Almada, RC; Calvo, F; Coimbra, NC; da Silva Soares, R; da Silva, JA; de Paiva, YB; Medeiros, P; Roncon, CM | 1 |
Liu, X; Ma, M; Wang, K; Wang, R; Wang, Y; Wei, S; Zhang, X; Zhao, L; Zhou, J | 1 |
Coimbra, NC; de Araújo Berber, RC; de Avila, DR; de Oliveira, RC; Maia Fernandes, BF; Oliveira, R; Pichinelli Maffei, TH; Santana, VC; Streg, RV; Vale, JS | 1 |
3 review(s) available for naloxonazine and naloxone
Article | Year |
---|---|
Multiple mu opiate receptors.
Topics: Aging; Analgesia; Animals; Autoradiography; Binding, Competitive; Brain; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylmaleimide; Morphine; Naloxone; Neurotransmitter Agents; Phylogeny; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Substance-Related Disorders; Tissue Distribution | 1986 |
Opioid receptors and their subtypes: focus on peripheral isolated tissue preparations.
Topics: Animals; GTP-Binding Proteins; Guinea Pigs; Humans; Mice; Naloxone; Narcotic Antagonists; Narcotics; Organ Specificity; Peripheral Nerves; Receptors, Opioid; Signal Transduction | 1994 |
Insights into mu opioid pharmacology the role of mu opioid receptor subtypes.
Topics: Alternative Splicing; Analgesia; Animals; Cloning, Molecular; Down-Regulation; Humans; Morphine; Morphine Derivatives; Naloxone; Narcotics; Receptors, Opioid, mu; RNA, Messenger; Trans-Activators | 2001 |
193 other study(ies) available for naloxonazine and naloxone
Article | Year |
---|---|
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor.
Topics: Animals; Binding, Competitive; Buprenorphine; CHO Cells; Cricetulus; Fluorescent Dyes; HEK293 Cells; Humans; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Radioligand Assay; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2015 |
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride | 1992 |
Evidence for differential opioid mu 1- and mu 2-receptor-mediated regulation of heart rate in the conscious rat.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Heart Rate; Injections, Intraventricular; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1992 |
Identification of a novel receptor mediating substance P-induced behavior in the mouse.
Topics: Analysis of Variance; Animals; Behavior, Animal; Binding Sites; Indoles; Injections, Spinal; Male; Mice; Morphinans; Naloxone; Naltrexone; Peptide Fragments; Substance P | 1992 |
The effects of selective mu1 opiate receptor blockade on breathing patterns in the fetal lamb.
Topics: Animals; Electromyography; Fetus; Gestational Age; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Sheep | 1991 |
Evaluation of receptor mechanism mediating fentanyl analgesia and toxicity.
Topics: Analgesics; Animals; Brain; Drug Tolerance; Fentanyl; Lethal Dose 50; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid | 1991 |
Inhibition of suckling-induced prolactin release by mu- and kappa-opioid antagonists.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Lactation; Luteinizing Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Prolactin; Rats; Rats, Inbred Strains; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1991 |
Comparison of naloxonazine and beta-funaltrexamine antagonism of mu 1 and mu 2 opioid actions.
Topics: Animals; Drug Administration Schedule; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Subcutaneous; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Respiratory and locomotor stimulation by low doses of dermorphin, a mu1 receptor-mediated effect.
Topics: Analgesics, Opioid; Animals; Flumazenil; Male; Motor Activity; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration | 1990 |
Dermorphin tetrapeptide analog induces naloxonazine-reversible respiratory stimulation.
Topics: Analgesics; Animals; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Respiration; Tidal Volume | 1990 |
Mu 1 opioid receptor involvement in maternal behavior.
Topics: Animals; Behavior, Animal; Female; Maternal Behavior; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1990 |
Irreversible opiate agonists and antagonists. II. Evidence against a bivalent mechanism of action for opiate azines and diacylhydrazones.
Topics: Animals; Binding, Competitive; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hydromorphone; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship | 1985 |
Opiate receptor inhibition improves the blunted baroreflex function in conscious dogs with right-sided congestive heart failure.
Topics: Animals; Blood Pressure; Consciousness; Dogs; Electrocardiography; Enkephalin, Leucine; Heart Failure; Naloxone; Narcotic Antagonists; Oxymorphone; Phenylephrine; Pressoreceptors; Receptors, Opioid; Reflex | 1989 |
Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice.
Topics: Analgesia; Anesthesia, Spinal; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Modulation of mu-mediated antinociception by delta agonists: characterization with antagonists.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1989 |
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.
Topics: Analgesia; Animals; Drug Tolerance; Gastrointestinal Motility; Male; Mice; Morphine; Morphine Derivatives; Naloxone | 1989 |
Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Motility; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1988 |
Differential blockade by naloxonazine of two mu opiate actions: analgesia and inhibition of gastrointestinal transit.
Topics: Analgesics; Animals; Gastrointestinal Transit; Male; Mice; Morphine; Naloxone; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu | 1988 |
Differential sensitivity of opioid-induced feeding to naloxone and naloxonazine.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Eating; Electroshock; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains | 1988 |
Opiate binding in calf thalamic membranes: a selective mu 1 binding assay.
Topics: Animals; Cattle; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus | 1988 |
Separation of opioid analgesia from respiratory depression: evidence for different receptor mechanisms.
Topics: Analgesia; Animals; Blood Gas Analysis; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration | 1985 |
Involvement of opioid receptor subtypes in rat feeding behavior.
Topics: Animals; Deoxyglucose; Feeding Behavior; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1985 |
Antagonism of morphine analgesia by intracerebroventricular naloxonazine.
Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1986 |
[Analgesic effect of metorphamide on skin pain and visceral pain].
Topics: Analgesics; Animals; Enkephalin, Methionine; Female; Male; Mice; Morphine; Naloxone; Pain; Rabbits; Receptors, Opioid; Receptors, Opioid, mu; Sensory Thresholds | 1986 |
Naloxonazine actions in vivo.
Topics: Animals; Brain; Kinetics; Male; Mice; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1986 |
Interaction of [D-Ser2,Leu5]enkephalin-Thr6 (DSLET), a relatively selective delta ligand, with mu1 opioid binding sites.
Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Male; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid | 1987 |
Naloxonazine and opioid-induced inhibition of reflex urinary bladder contractions.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Male; Muscle Contraction; Naloxone; Rats; Receptors, Opioid; Reflex; Urinary Bladder | 1987 |
Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Male; Motor Activity; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tegmentum Mesencephali | 1987 |
Naloxonazine effects on the interaction of enkephalin analogs with mu-1, mu and delta opioid binding sites in rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Comparison of effects of chronic administration of naloxone and naloxonazine upon food intake and maintainance of body weight in rats.
Topics: Aging; Animals; Appetite Depressants; Body Weight; Feeding Behavior; Male; Naloxone; Rats; Rats, Inbred Strains | 1988 |
The analgesic and respiratory depressant actions of metorphamide in mice and rabbits.
Topics: Analgesics; Animals; Depression, Chemical; Enkephalin, Methionine; Female; Injections, Intraventricular; Male; Mice; Naloxone; Rabbits; Respiration; Sensory Thresholds | 1985 |
Effects of beta-funaltrexamine in normal and morphine-dependent rhesus monkeys: observational studies.
Topics: Animals; Azocines; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Macaca mulatta; Morphine; Muscle Relaxation; Naloxone; Naltrexone; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors | 1985 |
Interaction of two phencyclidine opiate-like derivatives with 3H-opioid binding sites.
Topics: Analgesics; Animals; Binding, Competitive; Dihydromorphine; Male; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1984 |
[3H]-beta-endorphin binding in rat brain.
Topics: Animals; beta-Endorphin; Binding Sites; Binding, Competitive; Brain; Endorphins; Male; Naloxone; Rats; Rats, Inbred Strains; Tritium | 1984 |
Binding of [3H]naloxonazine to rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Hydrogen-Ion Concentration; Kinetics; Naloxone; Rats; Receptors, Opioid; Thermodynamics; Tissue Distribution | 1984 |
Evidence that naloxonazine produces prolonged antagonism of central delta opioid receptor activity in vivo.
Topics: Animals; Central Nervous System; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Urinary Bladder | 1984 |
Failure to demonstrate mu-isoreceptors.
Topics: Animals; Benzomorphans; Female; Mice; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, mu; Respiration | 1984 |
Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines.
Topics: Animals; Brain; Cell Membrane; Dihydromorphine; Drug Stability; Hydromorphone; Kinetics; Naloxone; Naltrexone; Oxymorphone; Receptors, Opioid; Structure-Activity Relationship | 1982 |
Dissociation of morphine's analgesic and respiratory depressant actions.
Topics: Analgesia; Animals; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Respiration | 1983 |
The binding to rat brain homogenates of Mr2034, a universal opiate.
Topics: Animals; Benzomorphans; Brain; Cyclazocine; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Male; Morphinans; Naloxone; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid | 1983 |
Specific mu 2 opioid isoreceptor regulation of nigrostriatal neurons: in vivo evidence with naloxonazine.
Topics: Animals; Corpus Striatum; Dopamine; Male; Morphine; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, mu; Substantia Nigra | 1983 |
Multiple mu receptors: evidence for mu2 sites in the guinea pig ileum.
Topics: Animals; Brain; Brain Chemistry; Dihydromorphine; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Naloxone; Oxymorphone; Receptors, Opioid; Receptors, Opioid, mu | 1983 |
Separation of morphine analgesia from physical dependence.
Topics: Analgesia; Animals; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
In vivo injection of antibodies directed against the cloned mu opioid receptor blocked supraspinal analgesia induced by mu-agonists in mice.
Topics: Amino Acid Sequence; Analgesia; Animals; Antibodies; Benzeneacetamides; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immunization, Passive; Male; Mice; Molecular Sequence Data; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1995 |
Antagonistic effect of buprenorphine on the antitussive effect of morphine is mediated via the activation of mu 1-opioid receptors.
Topics: Animals; Antitussive Agents; Buprenorphine; Capsaicin; Cough; Injections, Intraperitoneal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Receptors, Opioid, mu; Time Factors | 1995 |
Selective actions of central mu and kappa opioid antagonists upon sucrose intake in sham-fed rats.
Topics: Animals; Cerebral Ventricles; Eating; Enkephalin, Leucine-2-Alanine; Infusions, Parenteral; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sucrose | 1995 |
Reductions in body weight following chronic central opioid receptor subtype antagonists during development of dietary obesity in rats.
Topics: Animals; Body Weight; Dietary Fats; Eating; Male; Naloxone; Naltrexone; Narcotic Antagonists; Obesity; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Modification of mu-opioid agonist-induced locomotor activity and development of morphine dependence by diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid, mu; Streptozocin | 1995 |
Analysis of central opioid receptor subtype antagonism of hypotonic and hypertonic saline intake in water-deprived rats.
Topics: Animals; Enkephalin, Leucine-2-Alanine; Hypotonic Solutions; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saline Solution, Hypertonic; Water Deprivation | 1995 |
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline | 1995 |
Antinociceptive effect of dihydroetorphine in diabetic mice.
Topics: Analgesia; Analgesics, Opioid; Animals; Binding, Competitive; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Effect of diabetes on the morphine-induced inhibition of gastrointestinal transit.
Topics: Animals; Depression, Chemical; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gastrointestinal Transit; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone | 1995 |
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured | 1994 |
Effects of diabetes on the morphine-induced Straub tail reaction in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Reference Values; Tail | 1994 |
Central opioid receptor subtype mediation of isoproterenol-induced drinking in rats.
Topics: Animals; Drinking; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, mu | 1994 |
Effect of selective mu 1, mu 2 and delta 2 opioid receptor agonists on gastric functions in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Acid; Gastric Emptying; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Naltrexone; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach | 1994 |
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin | 1993 |
Beta-funaltrexamine blockade of opioid-induced inhibition of somatostatin secretion from rat stomach.
Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gastric Inhibitory Polypeptide; Gastric Mucosa; In Vitro Techniques; Male; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin | 1994 |
Streptozotocin-induced diabetes selectively reduces antinociception mediated by mu 1-opioid receptors, but not that mediated by mu 2-opioid receptors.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid, mu; Spinal Cord | 1994 |
TRIMU-5, a mu 2-opioid receptor agonist, stimulates the hypothalamo-pituitary-adrenal axis.
Topics: Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Kinetics; Male; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1994 |
Comparison of cardiovascular effects of mu- and delta-opioid receptor antagonists in dogs with congestive heart failure.
Topics: Animals; Blood Circulation; Cardiovascular System; Dogs; Enkephalin, Leucine; Heart Failure; Hemodynamics; Naloxone; Narcotic Antagonists; Receptors, Opioid, delta; Receptors, Opioid, mu; Regional Blood Flow; Ventricular Function, Right | 1994 |
The use of specific opioid agonists and antagonists to delineate the vagally mediated antinociceptive and cardiovascular effects of intravenous morphine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analysis of Variance; Animals; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heart Rate; Hexamethonium; Hexamethonium Compounds; Indoles; Injections, Intravenous; Male; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors; Vagotomy; Vagus Nerve | 1993 |
Characterization of the mu-opioid receptors on SH-SY5Y cells using beta-funaltrexamine (beta-FNA) and naloxonazine.
Topics: Analgesics; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid, mu; Tumor Cells, Cultured | 1993 |
Morphine induced analgesia is attenuated in post-partum lactating rats.
Topics: Analgesia; Animals; Diestrus; Female; Injections, Intravenous; Lactation; Male; Morphine; Naloxone; Postpartum Period; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1993 |
Opioid-induced stimulation of fetal respiratory activity by [D-Ala2]deltorphin I.
Topics: Animals; Dose-Response Relationship, Drug; Electromyography; Female; Fetus; Indoles; Injections, Intraventricular; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pregnancy; Receptors, Opioid, delta; Respiration; Sheep | 1993 |
Morphine-induced place preference in the CXBK mouse: characteristics of mu opioid receptor subtypes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Appetitive Behavior; Benzazepines; Choice Behavior; Conditioning, Classical; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Morphine; Motivation; Naloxone; Pyrrolidines; Receptors, Dopamine D1; Receptors, Opioid, mu; Sodium Chloride | 1993 |
Involvement of mu1 and mu2 opioid receptor subtypes in tail-pinch feeding in rats.
Topics: Animals; Arousal; Enkephalin, Leucine-2-Alanine; Feeding Behavior; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1993 |
Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains.
Topics: Analgesia; Animals; Brain Stem; Drug Administration Routes; Male; Mice; Morphine; Naloxone; Naltrexone; Receptors, Opioid, mu; Species Specificity; Spinal Cord | 1993 |
Possible involvement of mu 2-mediated mechanisms in mu-mediated antitussive activity in the mouse.
Topics: Analgesics; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Reaction Time; Receptors, Opioid, mu | 1993 |
Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats.
Topics: Animals; Heroin; Male; Naloxone; Naltrexone; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration | 1993 |
CRF alters the infundibular LHRH secretory system from the medial preoptic area of female rats: possible involvement of opioid receptors.
Topics: Animals; Corticotropin-Releasing Hormone; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Luteinizing Hormone; Naloxone; Naltrexone; Ovariectomy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1993 |
Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors?
Topics: Amino Acid Sequence; Analgesics; Animals; Catalepsy; Dose-Response Relationship, Drug; Male; Molecular Sequence Data; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Respiration | 1993 |
DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.
Topics: Analgesics; Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Male; Naloxone; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 1993 |
Role of mu 1- and delta-opioid receptors in modulation of fetal EEG and respiratory activity.
Topics: Animals; Electroencephalography; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Fetal Movement; Fetus; Morphine; Naloxone; Naltrexone; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiration; Sheep | 1993 |
Central opioid receptor subtype antagonists differentially reduce intake of saccharin and maltose dextrin solutions in rats.
Topics: Animals; Drinking Behavior; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Saccharin | 1993 |
Antagonist effects of beta-funaltrexamine and naloxonazine on alfentanil-induced antinociception and muscle rigidity in the rat.
Topics: Alfentanil; Analgesia; Animals; Electromyography; Male; Muscle Rigidity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar | 1993 |
Discriminative stimulus properties of morphine mediated by mu 1-opioid receptors.
Topics: Analgesics, Opioid; Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred F344; Receptors, Opioid, mu | 1995 |
Antinociceptive and behavioral effects of synthetic deltorphin analogs.
Topics: Analysis of Variance; Animals; Catalepsy; Dose-Response Relationship, Drug; Injections, Intraventricular; Locomotion; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Alcohol drinking is reduced by a mu 1- but not by a delta-opioid receptor antagonist in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking; Eating; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Intraperitoneal; Male; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Receptors, Opioid, mu | 1996 |
Naloxonazine antagonism of levorphanol-induced antinociception and respiratory depression in rhesus monkeys.
Topics: Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Levorphanol; Macaca mulatta; Naloxone; Narcotic Antagonists; Respiration; Respiratory Insufficiency | 1996 |
Reductions in locomotor activity following central opioid receptor subtype antagonists in rats.
Topics: Animals; Enkephalins; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley | 1996 |
Effects of selective opioid receptor antagonists on morphine-induced changes in striatal and limbic dopamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Limbic System; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Evidence for mu1-opioid receptor involvement in fentanyl-mediated respiratory depression.
Topics: Animals; Carbon Dioxide; Fentanyl; Naloxone; Oxygen; Rats; Receptors, Opioid, mu; Respiration; Respiratory Insufficiency | 1996 |
Different central opioid receptor subtype antagonists modify maltose dextrin and deprivation-induced water intake in sham feeding and sham drinking rats.
Topics: Animals; Dose-Response Relationship, Drug; Drinking; Eating; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Deprivation | 1996 |
Antinociceptive effect of buprenorphine in mu1-opioid receptor deficient CXBK mice.
Topics: Animals; Buprenorphine; Male; Mice; Mice, Inbred C57BL; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Species Specificity | 1997 |
Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism.
Topics: Animals; Benzoxazines; Dopamine; Dronabinol; Heroin; Male; Microdialysis; Morpholines; Naloxone; Naphthalenes; Narcotic Antagonists; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid, mu; Rimonabant | 1997 |
Involvement of opioid mu 1 receptors in morphine-induced conditioned place preference in rats.
Topics: Analgesics, Opioid; Animals; Body Temperature; Catalepsy; Conditioning, Operant; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, mu | 1997 |
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali | 1997 |
Conditioned immunomodulation: investigations of the role of endogenous activity at mu, kappa, and delta opioid receptor subtypes.
Topics: Animals; Avoidance Learning; Cell Division; Conditioning, Classical; Electroshock; Immune System; Killer Cells, Natural; Lipopolysaccharides; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Lew; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spleen | 1997 |
Morphine-6-glucuronide-induced locomotor stimulation in mice: role of opioid receptors.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Derivatives; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid | 1998 |
Identification of opioid receptor subtypes in antinociceptive actions of supraspinally-administered mitragynine in mice.
Topics: Analgesics; Animals; Drug Synergism; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain Measurement; Receptors, Opioid; Receptors, Opioid, mu; Secologanin Tryptamine Alkaloids | 1998 |
Respiratory and cardiovascular effects of the mu-opioid receptor agonist [Lys7]dermorphin in awake rats.
Topics: Analgesia; Animals; Blood Pressure; Hypercapnia; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Oligopeptides; Prosencephalon; Pulmonary Ventilation; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, Opioid, mu; Ritanserin; Serotonin Antagonists; Tidal Volume | 1998 |
A dopamine-mu1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse.
Topics: Animals; Dopamine; Food Preferences; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance-Related Disorders; Time Factors; Ventral Tegmental Area | 1998 |
Modulation of volitional ethanol intake in the rat by central delta-opioid receptors.
Topics: Alcohol Drinking; Animals; Enkephalin, Leucine; Male; Naloxone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta | 1998 |
Heroin antinociception changed from mu to delta receptor in streptozotocin-treated mice.
Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Benzylidene Compounds; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heroin; Injections, Intraventricular; Male; Mice; Morphine; Morphine Derivatives; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Receptors, Opioid, delta; Receptors, Opioid, mu; Streptozocin; Time Factors | 1998 |
Dynorphin A increases substance P release from trigeminal primary afferent C-fibers.
Topics: Animals; Animals, Newborn; Capsaicin; Dizocilpine Maleate; Dynorphins; Enkephalin, Leucine; Excitatory Amino Acid Antagonists; In Vitro Techniques; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
Contribution of spinal mu1-opioid receptors to morphine-induced antinociception.
Topics: Analgesics; Analgesics, Opioid; Animals; Drug Interactions; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Pain Measurement; Receptors, Opioid, mu; Spinal Cord | 1999 |
Activation of opioid mu-receptor by loperamide to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Animals; Antidiarrheals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose; Hyperglycemia; Injections, Intravenous; Loperamide; Male; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu | 1999 |
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain; Receptors, Opioid, mu; Time Factors | 1999 |
Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa.
Topics: Analgesics; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Plants, Medicinal; Receptors, Opioid; Secologanin Tryptamine Alkaloids; Thailand; Vas Deferens | 1999 |
Antagonistic effects of naloxone and naloxonazine on sufentanil-induced antinociception and respiratory depression in rats.
Topics: Analgesics, Opioid; Anesthesia, Spinal; Animals; Hypercapnia; Hypoxia; Injections, Intravenous; Injections, Spinal; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiration; Sufentanil | 1999 |
Antinociceptive properties of FR140423 mediated through spinal delta-, but not mu- and kappa-, opioid receptors.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Binding, Competitive; Diarrhea; Injections, Intraventricular; Injections, Spinal; Male; Membranes; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pyrazoles; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Sulfoxides | 1999 |
The antinociceptive effects of endomorphin-1 and endomorphin-2 in diabetic mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Inhibitory effect of intracerebroventricularly-administered [D-Arg(2), beta-Ala(4)]-dermorphin (1-4) on gastrointestinal transit.
Topics: Analgesics; Animals; Charcoal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Gastrointestinal Transit; Injections, Intraventricular; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides | 2000 |
Selective antagonism by naloxonazine of antinociception by Tyr-D-Arg-Phe-beta-Ala, a novel dermorphin analogue with high affinity at mu-opioid receptors.
Topics: Analgesics; Analgesics, Opioid; Animals; Drug Antagonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Pain Measurement; Receptors, Opioid, mu; Time Factors | 2000 |
Mercaptoacetate induces feeding through central opioid-mediated mechanisms in rats.
Topics: Animals; Antisense Elements (Genetics); Cloning, Molecular; Eating; Exons; Feeding Behavior; Injections, Intraperitoneal; Injections, Intraventricular; Locomotion; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereotyped Behavior; Thioglycolates | 2000 |
The effects of highly selective opioid receptor antagonists on the release of arginine vasotocin induced by hyperosmotic stimulation and angiotensin II injection.
Topics: Angiotensin II; Animals; Chickens; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saline Solution, Hypertonic; Vasotocin | 2000 |
Involvement of central opioid systems in human interferon-alpha induced immobility in the mouse forced swimming test.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Interferon-alpha; Interferon-beta; Interferon-gamma; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Swimming; Time Factors | 2000 |
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
Topics: Amino Acid Substitution; Animals; Benzamides; Benzomorphans; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes | 2000 |
Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heroin; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Receptors, Opioid, mu | 2000 |
Receptor binding and biological activity of the dermorphin analog Tyr-D-Arg(2)-Phe-Sar (TAPS).
Topics: Analgesics; Animals; Binding, Competitive; Catalepsy; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Injections, Spinal; Male; Muscle Contraction; Naloxone; Nociceptors; Oligopeptides; Opioid Peptides; Pulmonary Ventilation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Time Factors | 2001 |
Modulation of breathing by mu1 and mu2 opioid receptor stimulation in neonatal and adult rats.
Topics: Age Factors; Analgesics, Opioid; Animals; Animals, Newborn; Female; Fentanyl; Lung; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiratory Mechanics; Tidal Volume | 2001 |
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors | 2001 |
Plasma glucose-lowering effect of tramadol in streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gluconeogenesis; Glucose; Glucose Transporter Type 4; Glycogen; Hypoglycemic Agents; Injections, Intravenous; Kinetics; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Narcotics; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Receptors, Opioid, mu; RNA, Messenger; Tramadol | 2001 |
Endomorphin-1 improves scopolamine-induced impairment of short-term memory via mu1-opioid receptor in mice.
Topics: Analgesics, Opioid; Animals; Brain; Dose-Response Relationship, Drug; Drug Interactions; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Receptors, Opioid, mu; Scopolamine | 2001 |
Involvement of mu(1)-opioid receptors and cholinergic neurotransmission in the endomorphins-induced impairment of passive avoidance learning in mice.
Topics: Animals; Avoidance Learning; Cholinesterase Inhibitors; Injections, Intraventricular; Male; Memory; Mice; Naloxone; Narcotic Antagonists; Oligopeptides; Parasympathetic Nervous System; Physostigmine; Receptors, Opioid, mu; Synaptic Transmission | 2002 |
Opioid peptides inhibit excitatory but not inhibitory synaptic transmission in the rat dorsal motor nucleus of the vagus.
Topics: Animals; Brain Stem; Digestive System; Electric Stimulation; Endorphins; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Motor Neurons; Naloxone; Narcotic Antagonists; Neural Inhibition; Opioid Peptides; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Receptors, Opioid, mu; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 2002 |
mu-1 opioid receptor stimulation decreases body temperature in conscious, unrestrained neonatal rats.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Body Temperature; Female; Fentanyl; Male; Naloxone; Oligopeptides; Opioid Peptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Temperature; Time Factors | 2002 |
Release of beta-endorphin from adrenal gland to lower plasma glucose by the electroacupuncture at Zhongwan acupoint in rats.
Topics: Acupuncture Points; Adrenal Glands; Adrenalectomy; Animals; beta-Endorphin; Blood Glucose; Electroacupuncture; Hypoglycemia; Insulin; Male; Mice; Mice, Knockout; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu | 2002 |
Differential antagonism of endomorphin-1 and endomorphin-2 supraspinal antinociception by naloxonazine and 3-methylnaltrexone.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain; Pain Measurement; Quaternary Ammonium Compounds; Reflex; Time Factors | 2002 |
Lack of involvement of mu(1) opioid receptors in dermorphin-induced inhibition of hypoxic and hypercapnic ventilation in rat pups.
Topics: Age Factors; Analgesics, Opioid; Animals; Hypercapnia; Hypoxia; Naloxone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Oxygen; Rats; Rats, Wistar; Receptors, Opioid, mu; Respiratory Mechanics | 2002 |
Possible involvement of mu1-opioid receptors in the fentanyl- or morphine-induced antinociception at supraspinal and spinal sites.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, mu; Spinal Cord | 2002 |
Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Cues; Discrimination, Psychological; Ethanol; Extinction, Psychological; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration | 2002 |
Effects of the selective mu(1)-opioid receptor antagonist, naloxonazine, on cocaine-induced conditioned place preference and locomotor behavior in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Reward | 2002 |
Plasma glucose-lowering effect of beta-endorphin in streptozotocin-induced diabetic rats.
Topics: Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose; Hepatocytes; In Vitro Techniques; Male; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid, mu | 2002 |
Effects of beta-funaltrexamine and naloxonazine on single-trial morphine-conditioned place preference and locomotor activity.
Topics: Animals; Conditioning, Psychological; Male; Morphine; Motor Activity; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2003 |
Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.
Topics: Analgesics, Opioid; Animals; Antibodies, Blocking; Cloning, Molecular; Dynorphins; Endorphins; Enkephalin, Methionine; Guanosine 5'-O-(3-Thiotriphosphate); Hot Temperature; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Radioligand Assay; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
The antitussive effects of endomorphin-1 and endomorphin-2 in mice.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oligopeptides; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
Micro1-opioid antagonist naloxonazine alters ethanol discrimination and consumption.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Discrimination, Psychological; Dose-Response Relationship, Drug; Eating; Ethanol; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2003 |
Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of mu(1)- and kappa-opioid receptor blockade on escape behavior induced by electrical stimulation of the inferior colliculus.
Topics: Animals; Biotin; Dextrans; Dose-Response Relationship, Drug; Electric Stimulation; Escape Reaction; Fear; Inferior Colliculi; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Periaqueductal Gray; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2003 |
Differential opioid inhibition of C- and A delta- fiber mediated thermonociception after stimulation of the nucleus raphe magnus.
Topics: Analgesics, Opioid; Animals; Electric Stimulation; Female; Hot Temperature; Injections, Spinal; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Pathways; Nociceptors; Raphe Nuclei; Rats; Rats, Sprague-Dawley | 2004 |
Differential involvement of mu 1-opioid receptors in dermorphin tetrapeptide analogues-induced antinociception.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Male; Mice; Naloxone; Oligopeptides; Pain Measurement; Receptors, Opioid, mu | 2004 |
Supraspinal anti-allodynic and rewarding effects of endomorphins in rats.
Topics: Analgesics, Opioid; Animals; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nerve Compression Syndromes; Oligopeptides; Pain; Pain Management; Pain Measurement; Rats; Rats, Sprague-Dawley | 2004 |
Depressor and bradycardic responses to microinjections of endomorphin-2 into the NTS are mediated via ionotropic glutamate receptors.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Dose-Response Relationship, Drug; GABA Antagonists; Heart Rate; Male; Microinjections; Naloxone; Narcotic Antagonists; Oligopeptides; Parasympathetic Nervous System; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Stereotaxic Techniques; Vagus Nerve | 2004 |
The cardiovascular and renal effects of the potent and highly selective mu opioid agonist [Dmt1]DALDA.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Enzyme Inhibitors; Female; Gene Expression; Heart Rate; Hemodynamics; Homeostasis; Kidney; Myocardium; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Vasopressins | 2004 |
A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu | 2005 |
Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouse.
Topics: Analgesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hot Temperature; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Nociceptors; Oligopeptides; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu; Tail; Time Factors | 2005 |
Attenuation of aortic baroreflex responses by microinjections of endomorphin-2 into the rostral ventrolateral medullary pressor area of the rat.
Topics: Animals; Aorta; Baroreflex; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Male; Medulla Oblongata; Microinjections; Naloxone; Nervous System Physiological Phenomena; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, mu; Vagus Nerve | 2005 |
Effect of the blockade of mu1-opioid and 5HT2A-serotonergic/alpha1-noradrenergic receptors on sweet-substance-induced analgesia.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesia; Animals; Dose-Response Relationship, Drug; Ketanserin; Male; Methysergide; Naloxone; Naltrexone; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Serotonin Antagonists; Sucrose; Taste | 2005 |
Mu opiate active substances trefentanil and naloxonazine: tritiation at high specific activity.
Topics: Isotope Labeling; Magnetic Resonance Spectroscopy; Naloxone; Piperidines; Radiopharmaceuticals; Receptors, Opioid, mu; Tetrazoles; Tritium | 2005 |
Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways: involvement of GABAA and mu1-opioid receptors in the modulation of panic-like reactions elicited b
Topics: Animals; Bicuculline; Electric Stimulation; GABA Antagonists; Male; Mesencephalon; Microscopy, Electron; Naloxone; Narcotic Antagonists; Neural Pathways; Neurons; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, mu; Substantia Nigra; Tectum Mesencephali | 2005 |
The role of opioid receptor subtypes in the development of behavioral sensitization to ethanol.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Somatostatin; Time Factors | 2006 |
Effects of systemic administration of beta-casomorphin-5 on learning and memory in mice.
Topics: Analgesics; Animals; Avoidance Learning; Cattle; Dose-Response Relationship, Drug; Endorphins; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Memory; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid, mu; Scopolamine | 2006 |
Novel mechanism for plasma glucose-lowering action of metformin in streptozotocin-induced diabetic rats.
Topics: Adrenalectomy; Animals; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Hypoglycemic Agents; Male; Metformin; Mice; Naloxone; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Streptozocin | 2006 |
Modulation of anxiety by mu-opioid receptors of the lateral septal region in mice.
Topics: Animals; Anxiety; gamma-Aminobutyric Acid; Male; Maze Learning; Mice; Mice, Inbred BALB C; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Septal Nuclei | 2006 |
The effects of endomorphins and diprotin A on striatal dopamine release induced by electrical stimulation-an in vitro superfusion study in rats.
Topics: Animals; Corpus Striatum; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dopamine; Electric Stimulation; Infusion Pumps; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Oligopeptides; Organ Culture Techniques; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Wistar; Substantia Nigra; Synaptic Transmission | 2006 |
Daily increase of fat ingestion mediated via mu-opioid receptor signaling pathway.
Topics: Animals; Appetite Regulation; Corn Oil; Feeding Behavior; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides, Bacterial; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction | 2006 |
Involvement of mu1-opioid receptor on oxycodone-induced antinociception in diabetic mice.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Oxycodone; Receptors, Opioid, mu; Streptozocin | 2007 |
Structural determination of the novel fragmentation routes of zwitteronic morphine opiate antagonists naloxonazine and naloxone hydrochlorides using electrospray ionization tandem mass spectrometry.
Topics: Computer Simulation; Models, Chemical; Models, Molecular; Morphine; Naloxone; Opioid Peptides; Spectrometry, Mass, Electrospray Ionization | 2007 |
Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis.
Topics: Alcohol Drinking; Alcoholism; Animals; Basal Ganglia; Disease Models, Animal; Dopamine; Epistasis, Genetic; Ethanol; Genotype; Humans; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Naloxone; Nucleus Accumbens; Receptors, Opioid, mu; Reinforcement, Psychology; Sex Characteristics | 2007 |
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hot Temperature; Injections, Intraventricular; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Reaction Time; Receptors, Opioid, mu; Somatostatin; Time Factors | 2007 |
In vivo characterization of the effects of human hemokinin-1 and human hemokinin-1(4-11), mammalian tachykinin peptides, on the modulation of pain in mice.
Topics: Analgesics; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; Humans; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peptide Fragments; Piperidines; Receptors, Neurokinin-2; Tachykinins; Tropanes | 2008 |
Evidence for separate involvement of different mu-opioid receptor subtypes in itch and analgesia induced by supraspinal action of opioids.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Derivatives; Naloxone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Pruritus; Receptors, Opioid, mu; Time Factors | 2008 |
Possible involvement of dynorphin A release via mu1-opioid receptor on supraspinal antinociception of endomorphin-2.
Topics: Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Immune Sera; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating.
Topics: Analgesics, Opioid; Animals; Autoradiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Feeding Behavior; Guanosine 5'-O-(3-Thiotriphosphate); Male; Naloxone; Pons; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu | 2008 |
The effects of endomorphins on striatal [3H]GABA release induced by electrical stimulation: an in vitro superfusion study in rats.
Topics: Animals; Corpus Striatum; Dipeptidyl-Peptidase IV Inhibitors; Electric Stimulation; gamma-Aminobutyric Acid; Male; Naloxone; Naltrexone; Oligopeptides; Perfusion; Rats; Rats, Wistar; Receptors, Opioid, mu; Tritium | 2009 |
Intravenous self-administration of etonitazene alone and combined with cocaine in rhesus monkeys: comparison with heroin and antagonism by naltrexone and naloxonazine.
Topics: Animals; Benzimidazoles; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Female; Heroin; Injections, Intravenous; Macaca mulatta; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Substance Abuse, Intravenous | 2009 |
Opioid antagonist-induced regulation of the mu-opioid receptor expression in MCF-7 breast cancer cell line.
Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Estradiol; Humans; Naloxone; Narcotic Antagonists; Polymerase Chain Reaction; Receptors, Opioid, mu; RNA, Messenger; Up-Regulation | 2009 |
Selective mu- and kappa-opioid receptor antagonists administered into the nucleus accumbens interfere with rapid tolerance to ethanol in rats.
Topics: Animals; Drug Tolerance; Ethanol; Male; Microinjections; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2009 |
Mediation of protein kinase C zeta in mu-opioid receptor activation for increase of glucose uptake into cultured myoblast C2C12 cells.
Topics: Animals; Blotting, Western; Carbon Radioisotopes; Cell Line; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Indoles; Loperamide; Maleimides; Mice; Myoblasts, Skeletal; Naloxone; Narcotic Antagonists; Phosphorylation; Protein Kinase C; Receptors, Opioid, mu | 2009 |
Effect of opioid compounds on feeding and activity of the cockroach, Periplaneta americana.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Cockroaches; Eating; Female; Male; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, kappa; Receptors, Opioid, mu; Water Loss, Insensible | 2010 |
Opioid-salsolinol relationship in the control of prolactin release during lactation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Suckling; Brain; Dopamine; Female; Isoquinolines; Lactation; Naloxone; Narcotic Antagonists; Prolactin; Receptors, Opioid, mu; Sheep | 2010 |
Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model.
Topics: Analgesics; Animals; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Peptides, Cyclic; Receptors, Opioid, mu | 2010 |
Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors.
Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Loperamide; Male; Muscle Relaxation; Naloxone; Narcotic Antagonists; Potassium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Prostate; Rats; Rats, Wistar; Receptors, Opioid, mu | 2011 |
Effect of a nanostructured dendrimer-naloxonazine complex on endogenous opioid peptides μ1 receptor-mediated post-ictal antinociception.
Topics: Analgesia; Animals; Dendrimers; Drug Carriers; Male; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Polypropylenes; Rats; Rats, Wistar; Receptors, Opioid, mu; Seizures | 2011 |
Activation of peripheral opioid µ-receptors in blood vessel may lower blood pressure in spontaneously hypertensive rats.
Topics: Animals; Arteries; Blood Pressure; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium; Glyburide; Hemodynamics; Intracellular Signaling Peptides and Proteins; KATP Channels; Loperamide; Male; Morphinans; Naloxone; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid, mu; Vasodilation | 2011 |
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens.
Topics: Acetaldehyde; Animals; Enzyme Activation; Ethanol; Extracellular Signal-Regulated MAP Kinases; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Wistar; Receptors, Opioid, mu; Reinforcement, Psychology; Saccharin; Self Administration | 2011 |
A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit.
Topics: Animals; Antiprotozoal Agents; Cell Line, Tumor; Drug Discovery; High-Throughput Screening Assays; Host-Parasite Interactions; Humans; Leishmania; Leishmaniasis; Life Cycle Stages; Macrophages; Naloxone; Small Molecule Libraries | 2011 |
Inhibition of motility in isolated horse small intestine is mediated by κ but not µ opioid receptors.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Dose-Response Relationship, Drug; Fentanyl; Gastrointestinal Motility; Horses; Intestine, Small; Male; Morphine; Naloxone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2012 |
Endogenous opioid peptide-mediated neurotransmission in central and pericentral nuclei of the inferior colliculus recruits μ1-opioid receptor to modulate post-ictal antinociception.
Topics: Animals; Inferior Colliculi; Male; Naloxone; Opioid Peptides; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Opioid, mu; Seizures; Synaptic Transmission | 2012 |
YFa and analogs: investigation of opioid receptors in smooth muscle contraction.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Cholinergic Agonists; Dynorphins; Enkephalin, Methionine; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Oligopeptides; Receptors, Opioid; Vas Deferens | 2011 |
Regulation of growth hormone secretion in nursing ewes: an involvement of μ-receptor subtype.
Topics: Animals; Female; Growth Hormone; Guanidines; Infusions, Intraventricular; Lactation; Morphinans; Naloxone; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sheep | 2012 |
Opiate-induced constipation related to activation of small intestine opioid μ2-receptors.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gastrointestinal Transit; Glyburide; Humans; Intestine, Small; Loperamide; Male; Mice; Mice, Inbred BALB C; Morphinans; Muscle Relaxation; Naloxone; Receptors, Opioid, mu | 2012 |
Naloxonazine, a specific mu-opioid receptor antagonist, attenuates the increment of locomotor activity induced by acute methamphetamine in mice.
Topics: Animals; Blotting, Western; Corpus Striatum; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Drug Interactions; Male; Methamphetamine; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Narcotic Antagonists; Phosphorylation; Receptors, Opioid, mu; Video Recording | 2012 |
μ1- and 5-HT1-dependent mechanisms in the anterior pretectal nucleus mediate the antinociceptive effects of retrosplenial cortex stimulation in rats.
Topics: Animals; Atropine; Cerebral Cortex; Cobalt; Disease Models, Animal; Electric Stimulation Therapy; Male; Methiothepin; Naloxone; Pain Management; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid, mu; Receptors, Serotonin, 5-HT1 | 2012 |
Antinociceptive action of isolated mitragynine from Mitragyna Speciosa through activation of opioid receptor system.
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Male; Mice; Mice, Inbred ICR; Mitragyna; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Opioid; Secologanin Tryptamine Alkaloids | 2012 |
Involvement of μ-opioid receptors in antinociceptive action of botulinum toxin type A.
Topics: Analgesics; Animals; Botulinum Toxins, Type A; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Naltrexone; Narcotic Antagonists; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Receptors, Opioid, mu | 2013 |
Involvement of supraspinal and peripheral naloxonazine-insensitive opioid receptor sites in the expression of μ-opioid receptor agonist-induced physical dependence.
Topics: Animals; Free Radicals; Male; Mice; Naloxone; Peripheral Nervous System; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Substance-Related Disorders | 2013 |
Different types of opioid receptors involved in the suppression of LH secretion in lactating sheep.
Topics: Animals; Female; Gene Expression Regulation; Guanidines; Lactation; Luteinizing Hormone; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Sheep | 2013 |
Involvement of spinal release of α-neo-endorphin on the antinociceptive effect of TAPA.
Topics: Analgesia; Analgesics, Opioid; Animals; Endorphins; Gene Expression; Immune Sera; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord; Tail | 2013 |
The opioid system majorly contributes to preference for fat emulsions but not sucrose solutions in mice.
Topics: Administration, Oral; Animals; Behavior, Animal; Choice Behavior; Dietary Fats; Eating; Emulsions; Food Preferences; Male; Mice; Mice, Inbred BALB C; Naloxone; Naltrexone; Narcotic Antagonists; Phospholipids; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Soybean Oil; Sucrose | 2015 |
Prenatal exposure to vanilla or alcohol induces crawling after these odors in the neonate rat: The role of mu and kappa opioid receptor systems.
Topics: Analysis of Variance; Animals; Animals, Newborn; Drug-Seeking Behavior; Ethanol; Female; Locomotion; Maternal Exposure; Naloxone; Naltrexone; Odorants; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Vanilla | 2015 |
Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Astrocytes; Buprenorphine; Dose-Response Relationship, Drug; Hyperalgesia; In Vitro Techniques; Male; Naloxone; Nerve Fibers, Unmyelinated; Pain Measurement; Pain Threshold; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Spinal Nerve Roots; Synapses; Time Factors | 2015 |
Antinociceptive action of botulinum toxin type A in carrageenan-induced mirror pain.
Topics: Analgesics; Animals; Bicuculline; Botulinum Toxins, Type A; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Functional Laterality; Hyperalgesia; Male; Naloxone; Pain; Pain Measurement; Rats; Rats, Wistar; Spinal Cord; Synaptosomal-Associated Protein 25 | 2016 |
Opioid system mediated anti-nociceptive effect of agomelatine in mice.
Topics: Acetamides; Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Naltrexone; Pain; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rotarod Performance Test | 2016 |
Endogenous central amygdala mu-opioid receptor signaling promotes sodium appetite in mice.
Topics: Analgesics, Opioid; Animals; Appetite; Brain Mapping; Central Amygdaloid Nucleus; Mice; Naloxone; Neurons; Receptors, Opioid, mu; Signal Transduction; Sodium, Dietary | 2016 |
Naloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded Functions.
Topics: Animals; Host-Parasite Interactions; Humans; Leishmania donovani; Leishmaniasis; Macrolides; Macrophages; Naloxone; RNA, Small Interfering; Tissue Array Analysis; Vacuolar Proton-Translocating ATPases; Vacuoles | 2016 |
Opioid system contribution to the antidepressant-like action of m-trifluoromethyl-diphenyl diselenide in mice: A compound devoid of tolerance and withdrawal syndrome.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Depression; Depressive Disorder; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Organosilicon Compounds; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Swimming | 2017 |
Panicolytic-like effect of µ
Topics: Animals; Anxiety; Behavior, Animal; Crotalus; Disease Models, Animal; Fear; Food Chain; Inferior Colliculi; Naloxone; Narcotic Antagonists; Panic Disorder; Rats; Rats, Wistar; Receptors, Opioid, mu; Signal Transduction | 2019 |
The Blockade of µ1- and κ-Opioid Receptors in the Inferior Colliculus Decreases the Expression of Panic Attack-Like Behaviours Induced by Chemical Stimulation of the Dorsal Midbrain.
Topics: Animals; Behavior, Animal; Bicuculline; Exploratory Behavior; GABA-A Receptor Antagonists; Inferior Colliculi; Male; Mesencephalon; Naloxone; Naltrexone; Narcotic Antagonists; Neurons; Panic; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2019 |
Contribution of the μ opioid receptor and enkephalin to the antinociceptive actions of endomorphin-1 analogs with unnatural amino acid modifications in the spinal cord.
Topics: Analgesics; Animals; Chronic Pain; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Methionine; Enkephalins; Injections, Intraventricular; Mice; Naloxone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu; Spinal Cord | 2021 |
The blockade of μ‑opioid receptors in the lateral hypothalamus enhances panic attack‑like behaviour and diminishes defensive antinociception.
Topics: Animals; Behavior, Animal; Bicuculline; Fear; Hypothalamic Area, Lateral; Naloxone; Narcotic Antagonists; Nociception; Panic; Panic Disorder; Rats; Rats, Wistar; Receptors, Opioid, mu | 2022 |