naloxonazine and enkephalin, ala(2)-mephe(4)-gly(5)-

naloxonazine has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19908 (24.24)18.7374
1990's15 (45.45)18.2507
2000's9 (27.27)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L1
Briddon, SJ; Canals, M; Graham, B; Kellam, B; Scammells, PJ; Schembri, LS; Stoddart, LA1
Childers, SR; Nijssen, PC; Sexton, T1
Pasternak, GW; Paul, D; Pick, CG1
Bodnar, RJ; Gistrak, MA; Pasternak, GW; Paul, D1
Burks, TF; Heyman, JS; Mosberg, HI; Porreca, F; Williams, CL1
Clark, JA; Houghten, R; Pasternak, GW1
Itzhak, Y; Pasternak, GW1
Dray, A; Nunan, L; Wire, W1
Duffy, P; Kalivas, PW; Latimer, LG1
Cruciani, RA; Lutz, RA; Munson, PJ; Rodbard, D1
Dray, A; Nunan, L1
Garzón, J; Sánchez-Blázquez, P1
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Ohsawa, M; Saitoh, A; Suzuki, T1
Elliott, J; Lambert, DG; Smart, D; Traynor, JR2
Búzás, B; Cox, BM; Izenwasser, S1
Kwok, YN; McIntosh, C; Yago, V1
Eisenberg, RM2
Randich, A; Robertson, JD; Willingham, T1
Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Nagase, H; Suzuki, T1
Bontempi, B; Sharp, FR1
Fujimura, T; Kastin, AJ; Katsuyama, S; Murayama, K; Sakurada, S; Sakurada, T; Ueda, H; Yuki, M; Zadina, JE1
Esashi, A; Kisara, K; Nakagawasai, O; Niijima, F; Sakurada, S; Tadano, T; Takahashi, N; Tan-No, K; Yonezawa, A1
Hayashi, T; Kisara, K; Kutsuwa, M; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Takeda, S; Tan-No, K; Yuki, M1
Akil, H; Bonner, G; Meng, F1
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Sakurada, C; Sakurada, S; Sakurada, T; Takeshita, M; Yonezawa, A; Yuhki, M; Zadina, JE1
Fujimura, T; Hayashi, T; Kastin, AJ; Murayama, K; Narita, M; Orito, T; Sakurada, C; Sakurada, S; Sakurada, T; Suzuki, T; Tan-no, K; Tseng, LF; Yuhki, M; Zadina, JE1
Fujimura, T; Ito, K; Kawamura, S; Mizoguchi, H; Murayama, K; Nakayama, D; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H1
Mizoguchi, H; Nakayama, D; Sakurada, S; Sakurada, T; Watanabe, C; Watanabe, H1
Komatsu, T; Mizoguchi, H; Morimoto, M; Sakurada, S; Sakurada, T; Sato, T; Sawai, T; Watanabe, C; Watanabe, H; Yonezawa, A1
Aloyo, VJ; Chaijale, NN; Simansky, KJ1

Other Studies

33 other study(ies) available for naloxonazine and enkephalin, ala(2)-mephe(4)-gly(5)-

ArticleYear
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software

1994
Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting the μ-Opioid Receptor.
    Journal of medicinal chemistry, 2015, Dec-24, Volume: 58, Issue:24

    Topics: Animals; Binding, Competitive; Buprenorphine; CHO Cells; Cricetulus; Fluorescent Dyes; HEK293 Cells; Humans; Ligands; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Radioligand Assay; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship

2015
Opioid-inhibited adenylyl cyclase in rat brain membranes: lack of correlation with high-affinity opioid receptor binding sites.
    Journal of neurochemistry, 1992, Volume: 59, Issue:6

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding Sites; Brain; Cell Membrane; Colforsin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanosine Triphosphate; Male; Naloxone; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sodium; Sodium Chloride; Sodium Fluoride

1992
Comparison of naloxonazine and beta-funaltrexamine antagonism of mu 1 and mu 2 opioid actions.
    Life sciences, 1991, Volume: 48, Issue:21

    Topics: Animals; Drug Administration Schedule; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Subcutaneous; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu

1991
Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice.
    European journal of pharmacology, 1989, Sep-22, Volume: 168, Issue:3

    Topics: Analgesia; Anesthesia, Spinal; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1989
Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: studies with naloxonazine.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Gastrointestinal Motility; Injections, Intraventricular; Male; Mice; Morphine; Naloxone; Nociceptors; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1988
Opiate binding in calf thalamic membranes: a selective mu 1 binding assay.
    Molecular pharmacology, 1988, Volume: 34, Issue:3

    Topics: Animals; Cattle; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thalamus

1988
Interaction of [D-Ser2,Leu5]enkephalin-Thr6 (DSLET), a relatively selective delta ligand, with mu1 opioid binding sites.
    Life sciences, 1987, Jan-19, Volume: 40, Issue:3

    Topics: Animals; Binding Sites; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Kinetics; Male; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid

1987
Naloxonazine and opioid-induced inhibition of reflex urinary bladder contractions.
    Neuropharmacology, 1987, Volume: 26, Issue:1

    Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Male; Muscle Contraction; Naloxone; Rats; Receptors, Opioid; Reflex; Urinary Bladder

1987
Mu opioid receptor involvement in enkephalin activation of dopamine neurons in the ventral tegmental area.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Male; Motor Activity; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Tegmentum Mesencephali

1987
Naloxonazine effects on the interaction of enkephalin analogs with mu-1, mu and delta opioid binding sites in rat brain membranes.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1987
Evidence that naloxonazine produces prolonged antagonism of central delta opioid receptor activity in vivo.
    Brain research, 1984, Dec-03, Volume: 323, Issue:1

    Topics: Animals; Central Nervous System; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Urinary Bladder

1984
In vivo injection of antibodies directed against the cloned mu opioid receptor blocked supraspinal analgesia induced by mu-agonists in mice.
    Life sciences, 1995, Volume: 56, Issue:14

    Topics: Amino Acid Sequence; Analgesia; Animals; Antibodies; Benzeneacetamides; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immunization, Passive; Male; Mice; Molecular Sequence Data; Morphine; Naloxone; Peptide Fragments; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1995
Modification of mu-opioid agonist-induced locomotor activity and development of morphine dependence by diabetes.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Motor Activity; Naloxone; Naltrexone; Receptors, Opioid, mu; Streptozocin

1995
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
    European journal of pharmacology, 1994, Aug-16, Volume: 268, Issue:3

    Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured

1994
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin

1993
Beta-funaltrexamine blockade of opioid-induced inhibition of somatostatin secretion from rat stomach.
    European journal of pharmacology, 1994, Jul-11, Volume: 259, Issue:3

    Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gastric Inhibitory Polypeptide; Gastric Mucosa; In Vitro Techniques; Male; Molecular Sequence Data; Naloxone; Naltrexone; Narcotic Antagonists; Radioimmunoassay; Rats; Rats, Wistar; Somatostatin

1994
TRIMU-5, a mu 2-opioid receptor agonist, stimulates the hypothalamo-pituitary-adrenal axis.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Kinetics; Male; Naloxone; Naltrexone; Oligopeptides; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1994
The use of specific opioid agonists and antagonists to delineate the vagally mediated antinociceptive and cardiovascular effects of intravenous morphine.
    Brain research, 1993, Feb-19, Volume: 603, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analysis of Variance; Animals; Blood Pressure; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Heart Rate; Hexamethonium; Hexamethonium Compounds; Indoles; Injections, Intravenous; Male; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors; Vagotomy; Vagus Nerve

1993
Characterization of the mu-opioid receptors on SH-SY5Y cells using beta-funaltrexamine (beta-FNA) and naloxonazine.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Analgesics; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Kinetics; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid, mu; Tumor Cells, Cultured

1993
Possible involvement of mu 2-mediated mechanisms in mu-mediated antitussive activity in the mouse.
    Neuroscience letters, 1993, Jan-12, Volume: 149, Issue:2

    Topics: Analgesics; Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Reaction Time; Receptors, Opioid, mu

1993
DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:2

    Topics: Analgesics; Animals; Corticosterone; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hypothalamo-Hypophyseal System; Male; Naloxone; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

1993
Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21

    Topics: Afferent Pathways; Analgesics, Opioid; Animals; Behavior, Animal; Benzazepines; Bicuculline; Corpus Striatum; Dizocilpine Maleate; Dopamine Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Injections; Injections, Intraperitoneal; Interneurons; Morphine; Motor Activity; Naloxone; Nerve Tissue Proteins; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substantia Nigra; Tegmentum Mesencephali

1997
Differential involvement of mu-opioid receptor subtypes in endomorphin-1- and -2-induced antinociception.
    European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Oligopeptides; Pain; Receptors, Opioid, mu; Time Factors

1999
Inhibitory effect of intracerebroventricularly-administered [D-Arg(2), beta-Ala(4)]-dermorphin (1-4) on gastrointestinal transit.
    Peptides, 2000, Volume: 21, Issue:2

    Topics: Analgesics; Animals; Charcoal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Gastrointestinal Transit; Injections, Intraventricular; Mice; Mice, Inbred Strains; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides

2000
Selective antagonism by naloxonazine of antinociception by Tyr-D-Arg-Phe-beta-Ala, a novel dermorphin analogue with high affinity at mu-opioid receptors.
    European journal of pharmacology, 2000, Apr-28, Volume: 395, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Animals; Drug Antagonism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Pain Measurement; Receptors, Opioid, mu; Time Factors

2000
Selectivity of mu-opioid receptor determined by interfacial residues near third extracellular loop.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Amino Acid Substitution; Animals; Benzamides; Benzomorphans; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Ligands; Morphine; Mutation; Naloxone; Naltrexone; Narcotic Antagonists; Peptides; Piperazines; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, mu; Signal Transduction; Sulfur Radioisotopes

2000
Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone.
    Brain research, 2000, Oct-20, Volume: 881, Issue:1

    Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Heroin; Injections, Spinal; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Receptors, Opioid, mu

2000
Differential antinociceptive effects induced by intrathecally administered endomorphin-1 and endomorphin-2 in the mouse.
    European journal of pharmacology, 2001, Sep-21, Volume: 427, Issue:3

    Topics: Analgesics; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immune Sera; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Time Factors

2001
A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu

2005
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
    European journal of pharmacology, 2007, Jun-01, Volume: 563, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hot Temperature; Injections, Intraventricular; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Reaction Time; Receptors, Opioid, mu; Somatostatin; Time Factors

2007
Possible involvement of dynorphin A release via mu1-opioid receptor on supraspinal antinociception of endomorphin-2.
    Peptides, 2008, Volume: 29, Issue:9

    Topics: Analgesics; Animals; Dynorphins; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Immune Sera; Injections, Intraventricular; Male; Mice; Naloxone; Naltrexone; Oligopeptides; Protein Precursors; Receptors, Opioid, kappa; Receptors, Opioid, mu

2008
A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating.
    Brain research, 2008, Nov-13, Volume: 1240

    Topics: Analgesics, Opioid; Animals; Autoradiography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Feeding Behavior; Guanosine 5'-O-(3-Thiotriphosphate); Male; Naloxone; Pons; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu

2008