Compounds > nalidixic acid

nalidixic acid and probenecid

nalidixic acid has been researched along with probenecid in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (18.75)	18.7374
1990's	3 (18.75)	18.2507
2000's	2 (12.50)	29.6817
2010's	8 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Dash, H; Mills, J	1
Anderson, PG; Hekster, YA; Vree, TB	1
Buchle, AM; Fehr, B; Feldtrauer, JJ; Stoecklin, K; Waldmeier, PC	1
Irikura, T; Kusajima, H; Shimada, J; Uchida, H; Ueda, Y; Yamaji, T	1
Chiba, K; Hirano, T; Iwata, K; Miyazaki, S; Nakajima, Y; Oda, M; Sasaya, M; Takada, M	1
Hekster, YA; Van den Biggelaar-Martea, M; Van Ewijk-Beneken Kolmer, EW; Vree, TB	1

Reviews

2 review(s) available for nalidixic acid and probenecid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Contribution of the human kidney to the metabolic clearance of drugs. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:11 Topics: Glucuronates; Humans; Kidney; Liver; Metabolic Clearance Rate; Nalidixic Acid; Pharmacokinetics; Probenecid	1992

Other Studies

14 other study(ies) available for nalidixic acid and probenecid

Article	Year
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Letter: Severe metabolic acidosis associated with nalidixic acid overdose. Annals of internal medicine, 1976, Volume: 84, Issue:5 Topics: Acidosis; Adolescent; Drug Interactions; Humans; Male; Nalidixic Acid; Probenecid	1976
The effects of amfonelic acid on 5-HT metabolism in rat brain. Journal of neural transmission, 1983, Volume: 57, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Nalidixic Acid; Naphthyridines; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1983
Mechanism of renal excretion of AM-715, a new quinolonecarboxylic acid derivative, in rabbits, dogs, and humans. Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1 Topics: Adult; Animals; Anti-Infective Agents; Creatinine; Dogs; Humans; Kidney; Male; Metabolic Clearance Rate; Nalidixic Acid; Norfloxacin; Probenecid; Rabbits; Species Specificity	1983
[The uptake of nalidixic acid and enoxacin by rat renal cortical slices in rat]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1995, Volume: 115, Issue:5 Topics: Animals; Cimetidine; Enoxacin; In Vitro Techniques; Ion Transport; Kidney Cortex; Male; Nalidixic Acid; Probenecid; Rats; Rats, Wistar	1995
Probenecid inhibits the renal clearance and renal glucuronidation of nalidixic acid. A pilot experiment. Pharmacy world & science : PWS, 1993, Aug-20, Volume: 15, Issue:4 Topics: Depression, Chemical; Glucuronates; Half-Life; Humans; Kidney; Male; Middle Aged; Nalidixic Acid; Pilot Projects; Probenecid; Protein Binding	1993